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Wei Chen, Ph.D.

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University of California Los Angeles, Los Angeles, CA, USAPhD09/2019Chemistry and Biochemistry
National Taiwan University, Taipei, TaiwanMS07/2011Chemistry
National Taiwan University, Taipei, TaiwanBS06/2009Chemistry
International Association of Advanced Materials (IAAM) Young Scientist Award & Medal
Inorganic Faculty Chemistry Dissertation Award (Outstanding Research Achievements in Chemistry) UCLA
Ralph & Charlene Bauer Award for research in Inorganic Chemistry, UCLA
Doctoral Student Travel Grant Award for Conference, UCLA
Mautner Graduate Award (For meritorious graduate students in UCLA)
Southern California Scholarship Award, Yin Chin Foundation USA and STUF United. Fund Inc.
Government Scholarship to Study Abroad, Ministry of Education, Taiwan
Dean’s Scholar Award, UCLA
Master Thesis Award, National Taiwan University
Dean's Award (For master students ranked within top 10% of the class), National Taiwan University
Travel Grant for International Conference, National Science Council, Taiwan
Mr. Kao Ying-Shih Research Scholarship. (For graduate students who ranked 1st of the class)
2010 - Now
Honorary Member, The Phi Tau Phi Scholastic Honor Society
Thesis Award in Nanomaterial Chemistry, The Chinese Chemical Society
Dean's Award, National Taiwan University
The Research Creativity Award, National Science Council, Taiwan
2008 - 2009
Research Proposals Grant for College-Level Students, National Science Council, Taiwan


Featured Content

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Jiang Ouyang, Wei Chen*, Wei Tao*. Matter (Cell Press). Design of application-optimized hydrogels based on a swollen polymer network model. 2022; 5(8):2471-2473. View Publication.
  2. Xiao Y, Tang Z, Huang X, Chen W, Zhou J, Liu H, Liu C, Kong N, Tao W. Emerging mRNA technologies: delivery strategies and biomedical applications. Chem Soc Rev. 2022 May 23; 51(10):3828-3845. PMID: 35437544.
    Citations:    Fields:    Translation:HumansPHPublic Health
  3. Ouyang J, Rao S, Liu R, Wang L, Chen W, Tao W, Kong N. 2D materials-based nanomedicine: From discovery to applications. Adv Drug Deliv Rev. 2022 06; 185:114268. PMID: 35398466.
    Citations: 1     Fields:    Translation:Humans
  4. Zhang D, Zhong D, Ouyang J, He J, Qi Y, Chen W, Zhang X, Tao W, Zhou M. Microalgae-based oral microcarriers for gut microbiota homeostasis and intestinal protection in cancer radiotherapy. Nat Commun. 2022 03 17; 13(1):1413. PMID: 35301299; PMCID: PMC8931093.
    Citations: 3     Fields:    Translation:Humans
  5. Ferdows BM, Patel DN, Chen W*, Huang X, Kong N, Tao W*. RNA Cancer Nanomedicine: Nanotechnology-mediated RNA Therapy. Nanoscale. 2022. View Publication.
  6. Chen W, Tao W. Precise control of the structure of synthetic hydrogel networks for precision medicine applications. Matter (Cell Press). 2022; 5(1):18-19. View Publication.
  7. Zhong D, Zhang D, Chen W, He J, Ren C, Zhang X, Kong N, Tao W, Zhou M. Orally deliverable strategy based on microalgal biomass for intestinal disease treatment. Sci Adv. 2021 Nov 26; 7(48):eabi9265. PMID: 34818040; PMCID: PMC8612690.
    Citations: 3     Fields:    
  8. Chen W, Schilperoort M, Cao Y, Shi J, Tabas I, Tao W. Macrophage-targeted nanomedicine for the diagnosis and treatment of atherosclerosis. Nat Rev Cardiol. 2022 Apr; 19(4):228-249. PMID: 34759324; PMCID: PMC8580169.
    Citations: 14     Fields:    Translation:HumansCells
  9. Huang X, Wu G, Liu C, Hua X, Tang Z, Xiao Y, Chen W, Zhou J, Kong N, Huang P, Shi J, Tao W. Intercalation-Driven Formation of siRNA Nanogels for Cancer Therapy. Nano Lett. 2021 11 24; 21(22):9706-9714. PMID: 34723546.
    Citations: 2     Fields:    Translation:Humans
  10. Zhou J, Zhang Z, Joseph J, Zhang X, Ferdows B, Patel D, Chen W, Banfi G, Molinaro R, Cosco D, Kong N, Joshi N, Farokhzad O, Corbo C, Tao W. Biomaterials and nanomedicine for bone regeneration: Progress and future prospects. Exploration. 2021; 1:20210011.
  11. Xiao Y, Tang Z, Huang X, Joseph J, Chen W, Liu C, Zhou J, Kong N, Joshi N, Du J, Tao W. Glucose-responsive oral insulin delivery platform for one treatment a day in diabetes. Matter (Cell Press). 2021; 4(10):3269-3285.
  12. Liu C, Sun S, Feng Q, Wu G, Wu Y, Kong N, Yu Z, Yao J, Zhang X, Chen W, Tang Z, Xiao Y, Huang X, Lv A, Yao C, Cheng H, Wu A, Xie T, Tao W. Arsenene Nanodots with Selective Killing Effects and their Low-Dose Combination with ß-Elemene for Cancer Therapy. Adv Mater. 2021 Sep; 33(37):e2102054. PMID: 34309925.
    Citations: 15     Fields:    Translation:HumansAnimalsCells
  13. Tang Z, Xiao Y, Kong N, Liu C, Chen W, Huang X, Xu D, Ouyang J, Feng C, Wang C, Wang J, Zhang H, Tao W. Nano-bio interfaces effect of two-dimensional nanomaterials and their applications in cancer immunotherapy. Acta Pharm Sin B. 2021 Nov; 11(11):3447-3464. PMID: 34900529.
    Citations: 5     
  14. Chen W, Cheng CA, Xiang D, Zink JI. Expanding nanoparticle multifunctionality: size-selected cargo release and multiple logic operations. Nanoscale. 2021 Mar 18; 13(10):5497-5506. PMID: 33687426.
    Citations: 1     Fields:    
  15. Ouyang J, Zhang L, Li L, Chen W, Tang Z, Ji X, Feng C, Tao N, Kong N, Chen T, Liu YN, Tao W. Cryogenic Exfoliation of 2D Stanene Nanosheets for Cancer Theranostics. Nanomicro Lett. 2021 Mar 10; 13(1):90. PMID: 34138343; PMCID: PMC8006518.
    Citations: 4     
  16. Chen W, Liu C, Ji X, Joseph J, Tang Z, Ouyang J, Xiao Y, Kong N, Joshi N, Farokhzad OC, Tao W, Xie T. Stanene-Based Nanosheets for ß-Elemene Delivery and Ultrasound-Mediated Combination Cancer Therapy. Angew Chem Int Ed Engl. 2021 03 22; 60(13):7155-7164. PMID: 33434327.
    Citations: 13     Fields:    Translation:HumansCells
  17. Ji X, Ge L, Liu C, Tang Z, Xiao Y, Chen W, Lei Z, Gao W, Blake S, De D, Shi B, Zeng X, Kong N, Zhang X, Tao W. Capturing functional two-dimensional nanosheets from sandwich-structure vermiculite for cancer theranostics. Nat Commun. 2021 02 18; 12(1):1124. PMID: 33602928; PMCID: PMC7892577.
    Citations: 33     Fields:    Translation:HumansAnimalsCells
  18. Cheng CA, Chen W, Zhang L, Wu HH, Zink JI. Magnetic resonance imaging of high-intensity focused ultrasound-stimulated drug release from a self-reporting core@shell nanoparticle platform. Chem Commun (Camb). 2020 Sep 14; 56(71):10297-10300. PMID: 32756711.
    Citations: 4     Fields:    Translation:Cells
  19. Sun DL, Poddar S, Pan RD, Rosser EW, Abt ER, Van Valkenburgh J, Le TM, Lok V, Hernandez SP, Song J, Li J, Turlik A, Chen X, Cheng CA, Chen W, Mona CE, Stuparu AD, Vergnes L, Reue K, Damoiseaux R, Zink JI, Czernin J, Donahue TR, Houk KN, Jung ME, Radu CG. Isoquinoline thiosemicarbazone displays potent anticancer activity with in vivo efficacy against aggressive leukemias. RSC Med Chem. 2020 Mar 01; 11(3):392-410. PMID: 33479645.
    Citations: 1     
  20. Ruan L, Chen W, Wang R, Lu J, Zink JI. Magnetically Stimulated Drug Release Using Nanoparticles Capped by Self-Assembling Peptides. ACS Appl Mater Interfaces. 2019 Nov 27; 11(47):43835-43842. PMID: 31661236.
    Citations: 7     Fields:    Translation:HumansCells
  21. Cheng CA, Chen W, Zhang L, Wu HH, Zink JI. A Responsive Mesoporous Silica Nanoparticle Platform for Magnetic Resonance Imaging-Guided High-Intensity Focused Ultrasound-Stimulated Cargo Delivery with Controllable Location, Time, and Dose. J Am Chem Soc. 2019 11 06; 141(44):17670-17684. PMID: 31604010.
    Citations: 16     Fields:    Translation:AnimalsCells
  22. Chen W. Design and Synthesis of Multifunctional Mesoporous Silica Nanoparticles for Drug Delivery and Bioimaging Applications. 2019.
  23. Chen W, Cheng CA, Cosco ED, Ramakrishnan S, Lingg JGP, Bruns OT, Zink JI, Sletten EM. Shortwave Infrared Imaging with J-Aggregates Stabilized in Hollow Mesoporous Silica Nanoparticles. J Am Chem Soc. 2019 08 14; 141(32):12475-12480. PMID: 31353894.
    Citations: 15     Fields:    Translation:Animals
  24. Tsai PH, Wang ML, Chang JH, Yarmishyn AA, Nhi Nguyen PN, Chen W, Chien Y, Huo TI, Mou CY, Chiou SH. Dual Delivery of HNF4a and Cisplatin by Mesoporous Silica Nanoparticles Inhibits Cancer Pluripotency and Tumorigenicity in Hepatoma-Derived CD133-Expressing Stem Cells. ACS Appl Mater Interfaces. 2019 Jun 05; 11(22):19808-19818. PMID: 31066542.
    Citations: 11     Fields:    Translation:HumansAnimalsCells
  25. Chen W, Glackin CA, Horwitz MA, Zink JI. Nanomachines and Other Caps on Mesoporous Silica Nanoparticles for Drug Delivery. Acc Chem Res. 2019 06 18; 52(6):1531-1542. PMID: 31082188.
    Citations: 25     Fields:    Translation:HumansAnimalsCells
  26. Ray S, Cheng CA, Chen W, Li Z, Zink JI, Lin YY. Magnetic Heating Stimulated Cargo Release with Dose Control using Multifunctional MR and Thermosensitive Liposome. Nanotheranostics. 2019; 3(2):166-178. PMID: 31183312.
    Citations: 8     Fields:    Translation:Humans
  27. Chen W, Cheng CA, Zink JI. Spatial, Temporal, and Dose Control of Drug Delivery using Noninvasive Magnetic Stimulation. ACS Nano. 2019 02 26; 13(2):1292-1308. PMID: 30633500.
    Citations: 27     Fields:    Translation:HumansCells
  28. Kumar N, Chen W, Cheng CA, Deng T, Wang R, Zink JI. Stimuli-Responsive Nanomachines and Caps for Drug Delivery. Enzymes. 2018; 43:31-65. PMID: 30244808.
    Citations: 4     Fields:    Translation:Cells
  29. Chen W, Cheng CA, Lee BY, Clemens DL, Huang WY, Horwitz MA, Zink JI. Facile Strategy Enabling Both High Loading and High Release Amounts of the Water-Insoluble Drug Clofazimine Using Mesoporous Silica Nanoparticles. ACS Appl Mater Interfaces. 2018 Sep 26; 10(38):31870-31881. PMID: 30160469.
    Citations: 16     Fields:    
  30. Chou CC, Chen W, Hung Y, Mou CY. Molecular Elucidation of Biological Response to Mesoporous Silica Nanoparticles in Vitro and in Vivo. ACS Appl Mater Interfaces. 2017 Jul 12; 9(27):22235-22251. PMID: 28608695.
    Citations: 23     Fields:    Translation:HumansAnimals
  31. Chang JH, Tsai PH, Chen W, Chiou SH, Mou CY. Dual delivery of siRNA and plasmid DNA using mesoporous silica nanoparticles to differentiate induced pluripotent stem cells into dopaminergic neurons. J Mater Chem B. 2017 Apr 28; 5(16):3012-3023. PMID: 32263993.
    Citations: 9     Fields:    
  32. Guardado-Alvarez TM, Chen W, Norton AE, Russell MM, Connick WB, Zink JI. Analyte-responsive gated hollow mesoporous silica nanoparticles exhibiting inverse functionality and an AND logic response. Nanoscale. 2016 Nov 03; 8(43):18296-18300. PMID: 27779267.
    Citations: 3     Fields:    
  33. Chen JY, Ho CY, Lu ML, Chu LJ, Chen KC, Chu SW, Chen W, Mou CY, Chen YF. Efficient spin-light emitting diodes based on InGaN/GaN quantum disks at room temperature: a new self-polarized paradigm. Nano Lett. 2014 Jun 11; 14(6):3130-7. PMID: 24807793.
    Citations: 3     Fields:    
  34. Chen W, Tsai PH, Hung Y, Chiou SH, Mou CY. Nonviral cell labeling and differentiation agent for induced pluripotent stem cells based on mesoporous silica nanoparticles. ACS Nano. 2013 Oct 22; 7(10):8423-40. PMID: 24063246.
    Citations: 19     Fields:    Translation:AnimalsCells
  35. Wu P, Yuan SS, Ho CC, Hsieh WY, Hong QS, Yu SL, Chen W, Chen HY, Wang CD, Li KC, Yang PC, Chen HW. Focal amplification of HOXD-harboring chromosome region is implicated in multiple-walled carbon nanotubes-induced carcinogenicity. Nano Lett. 2013 Oct 09; 13(10):4632-41. PMID: 23984819.
    Citations: 4     Fields:    Translation:HumansCells
  36. Li LH, Yen MY, Ho CC, Wu P, Wang CC, Maurya PK, Chen PS, Chen W, Hsieh WY, Chen HW. Non-cytotoxic nanomaterials enhance antimicrobial activities of cefmetazole against multidrug-resistant Neisseria gonorrhoeae. PLoS One. 2013; 8(5):e64794. PMID: 23705013.
    Citations: 13     Fields:    Translation:HumansCells
  37. Chen W, Lu F, Chen CC, Mo KC, Hung Y, Guo ZX, Lin CH, Lin MH, Lin YH, Chang C, Mou CY. Manganese-enhanced MRI of rat brain based on slow cerebral delivery of manganese(II) with silica-encapsulated Mn x Fe(1-x) O nanoparticles. NMR Biomed. 2013 Sep; 26(9):1176-85. PMID: 23526743.
    Citations: 4     Fields:    Translation:AnimalsCells
  38. Wu SH, Lin CY, Hung Y, Chen W, Chang C, Mou CY. PEGylated silica nanoparticles encapsulating multiple magnetite nanocrystals for high-performance microscopic magnetic resonance angiography. J Biomed Mater Res B Appl Biomater. 2011 Oct; 99(1):81-8. PMID: 21800422.
    Citations: 7     Fields:    Translation:HumansAnimalsCells
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.