Harvard Catalyst Profiles

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Amit Meller, Ph.D.

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Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Alfaro JA, Bohländer P, Dai M, Filius M, Howard CJ, van Kooten XF, Ohayon S, Pomorski A, Schmid S, Aksimentiev A, Anslyn EV, Bedran G, Cao C, Chinappi M, Coyaud E, Dekker C, Dittmar G, Drachman N, Eelkema R, Goodlett D, Hentz S, Kalathiya U, Kelleher NL, Kelly RT, Kelman Z, Kim SH, Kuster B, Rodriguez-Larrea D, Lindsay S, Maglia G, Marcotte EM, Marino JP, Masselon C, Mayer M, Samaras P, Sarthak K, Sepiashvili L, Stein D, Wanunu M, Wilhelm M, Yin P, Meller A, Joo C. The emerging landscape of single-molecule protein sequencing technologies. Nat Methods. 2021 06; 18(6):604-617. PMID: 34099939.
    Citations: 3     Fields:    
  2. Burck N, Gilboa T, Gadi A, Patkin Nehrer M, Schneider RJ, Meller A. Nanopore Identification of Single Nucleotide Mutations in Circulating Tumor DNA by Multiplexed Ligation. Clin Chem. 2021 Apr 29; 67(5):753-762. PMID: 33496315.
    Citations: 2     Fields:    
  3. Rozevsky Y, Gilboa T, van Kooten XF, Kobelt D, Huttner D, Stein U, Meller A. Quantification of mRNA Expression Using Single-Molecule Nanopore Sensing. ACS Nano. 2020 10 27; 14(10):13964-13974. PMID: 32930583.
    Citations: 8     Fields:    Translation:HumansCells
  4. Spitzberg JD, van Kooten XF, Bercovici M, Meller A. Microfluidic device for coupling isotachophoretic sample focusing with nanopore single-molecule sensing. Nanoscale. 2020 Sep 14; 12(34):17805-17811. PMID: 32820758.
    Citations: 3     Fields:    
  5. Spitzberg JD, Zrehen A, van Kooten XF, Meller A. Plasmonic-Nanopore Biosensors for Superior Single-Molecule Detection. . 2019 Jun; 31(23):e1900422. PMID: 30941823.
    Citations: 13     
  6. Varongchayakul N, Song J, Meller A, Grinstaff MW. Single-molecule protein sensing in a nanopore: a tutorial. Chem Soc Rev. 2018 Nov 26; 47(23):8512-8524. PMID: 30328860.
    Citations: 31     Fields:    Translation:Humans
  7. Rudnizky S, Khamis H, Malik O, Squires AH, Meller A, Melamed P, Kaplan A. Single-molecule DNA unzipping reveals asymmetric modulation of a transcription factor by its binding site sequence and context. Nucleic Acids Res. 2018 02 16; 46(3):1513-1524. PMID: 29253225.
    Citations: 6     Fields:    Translation:HumansCells
  8. Assad ON, Gilboa T, Spitzberg J, Juhasz M, Weinhold E, Meller A. Light-Enhancing Plasmonic-Nanopore Biosensor for Superior Single-Molecule Detection. . 2017 Mar; 29(9). PMID: 28026129.
    Citations: 9     
  9. Squires A, Atas E, Meller A. Nanopore sensing of individual transcription factors bound to DNA. Sci Rep. 2015 Jun 25; 5:11643. PMID: 26109509.
    Citations: 19     Fields:    Translation:HumansAnimalsCells
  10. Nir I, Huttner D, Meller A. Direct Sensing and Discrimination among Ubiquitin and Ubiquitin Chains Using Solid-State Nanopores. Biophys J. 2015 May 05; 108(9):2340-9. PMID: 25954891.
    Citations: 24     Fields:    Translation:Cells
  11. Squires A, Meller A. DNA capture and translocation through nanoscale pores-a fine balance of electrophoresis and electroosmosis. Biophys J. 2013 Aug 06; 105(3):543-4. PMID: 23931300.
    Citations: 5     Fields:    Translation:Cells
  12. Atas E, Singer A, Meller A. DNA sequencing and bar-coding using solid-state nanopores. Electrophoresis. 2012 Dec; 33(23):3437-47. PMID: 23109189.
    Citations: 8     Fields:    Translation:HumansCells
  13. Lin J, Fabian M, Sonenberg N, Meller A. Nanopore detachment kinetics of poly(A) binding proteins from RNA molecules reveals the critical role of C-terminus interactions. Biophys J. 2012 Mar 21; 102(6):1427-34. PMID: 22455926.
    Citations: 18     Fields:    Translation:HumansCells
  14. McNally B, Singer A, Yu Z, Sun Y, Weng Z, Meller A. Optical recognition of converted DNA nucleotides for single-molecule DNA sequencing using nanopore arrays. Nano Lett. 2010 Jun 09; 10(6):2237-44. PMID: 20459065.
    Citations: 56     Fields:    Translation:Cells
  15. Di Fiori N, Meller A. The Effect of dye-dye interactions on the spatial resolution of single-molecule FRET measurements in nucleic acids. Biophys J. 2010 May 19; 98(10):2265-72. PMID: 20483335.
    Citations: 21     Fields:    Translation:Cells
  16. Lin J, Kolomeisky A, Meller A. Helix-coil kinetics of individual polyadenylic acid molecules in a protein channel. Phys Rev Lett. 2010 Apr 16; 104(15):158101. PMID: 20482020.
    Citations: 12     Fields:    Translation:Cells
  17. Singer A, Wanunu M, Morrison W, Kuhn H, Frank-Kamenetskii M, Meller A. Nanopore based sequence specific detection of duplex DNA for genomic profiling. Nano Lett. 2010 Feb 10; 10(2):738-42. PMID: 20088590.
    Citations: 51     Fields:    Translation:HumansCells
  18. Dudko OK, Mathé J, Meller A. Nanopore force spectroscopy tools for analyzing single biomolecular complexes. Methods Enzymol. 2010; 475:565-89. PMID: 20627171.
    Citations: 8     Fields:    Translation:Cells
  19. Soni GV, Singer A, Yu Z, Sun Y, McNally B, Meller A. Synchronous optical and electrical detection of biomolecules traversing through solid-state nanopores. Rev Sci Instrum. 2010 Jan; 81(1):014301. PMID: 20113116.
    Citations: 23     Fields:    
  20. Wanunu M, Morrison W, Rabin Y, Grosberg AY, Meller A. Electrostatic focusing of unlabelled DNA into nanoscale pores using a salt gradient. Nat Nanotechnol. 2010 Feb; 5(2):160-5. PMID: 20023645.
    Citations: 159     Fields:    Translation:Cells
  21. Wanunu M, Sutin J, Meller A. DNA profiling using solid-state nanopores: detection of DNA-binding molecules. Nano Lett. 2009 Oct; 9(10):3498-502. PMID: 19585985.
    Citations: 23     Fields:    Translation:Cells
  22. Branton D, Deamer DW, Marziali A, Bayley H, Benner SA, Butler T, Di Ventra M, Garaj S, Hibbs A, Huang X, Jovanovich SB, Krstic PS, Lindsay S, Ling XS, Mastrangelo CH, Meller A, Oliver JS, Pershin YV, Ramsey JM, Riehn R, Soni GV, Tabard-Cossa V, Wanunu M, Wiggin M, Schloss JA. The potential and challenges of nanopore sequencing. Nat Biotechnol. 2008 Oct; 26(10):1146-53. PMID: 18846088.
    Citations: 585     Fields:    
  23. McNally B, Wanunu M, Meller A. Electromechanical unzipping of individual DNA molecules using synthetic sub-2 nm pores. Nano Lett. 2008 Oct; 8(10):3418-22. PMID: 18759490.
    Citations: 32     Fields:    Translation:Cells
  24. Wanunu M, Sutin J, McNally B, Chow A, Meller A. DNA translocation governed by interactions with solid-state nanopores. Biophys J. 2008 Nov 15; 95(10):4716-25. PMID: 18708467.
    Citations: 126     Fields:    Translation:Cells
  25. Wanunu M, Chakrabarti B, Mathé J, Nelson DR, Meller A. Orientation-dependent interactions of DNA with an alpha-hemolysin channel. Phys Rev E Stat Nonlin Soft Matter Phys. 2008 Mar; 77(3 Pt 1):031904. PMID: 18517419.
    Citations: 11     Fields:    Translation:Cells
  26. Soni GV, Meller A. Progress toward ultrafast DNA sequencing using solid-state nanopores. Clin Chem. 2007 Nov; 53(11):1996-2001. PMID: 17890440.
    Citations: 21     Fields:    Translation:HumansCells
  27. Wanunu M, Meller A. Chemically modified solid-state nanopores. . 2007 Jun; 7(6):1580-5. PMID: 17503868.
    Citations: 76     Translation:Cells
  28. Dudko OK, Mathé J, Szabo A, Meller A, Hummer G. Extracting kinetics from single-molecule force spectroscopy: nanopore unzipping of DNA hairpins. Biophys J. 2007 Jun 15; 92(12):4188-95. PMID: 17384066.
    Citations: 59     Fields:    Translation:Cells
  29. Hornblower B, Coombs A, Whitaker RD, Kolomeisky A, Picone SJ, Meller A, Akeson M. Single-molecule analysis of DNA-protein complexes using nanopores. Nat Methods. 2007 Apr; 4(4):315-7. PMID: 17339846.
    Citations: 98     Fields:    Translation:Cells
  30. Edel JB, Eid JS, Meller A. Accurate single molecule FRET efficiency determination for surface immobilized DNA using maximum likelihood calculated lifetimes. J Phys Chem B. 2007 Mar 22; 111(11):2986-90. PMID: 17388421.
    Citations: 9     Fields:    Translation:Cells
  31. Bonthuis DJ, Zhang J, Hornblower B, Mathé J, Shklovskii BI, Meller A. Self-energy-limited ion transport in subnanometer channels. Phys Rev Lett. 2006 Sep 22; 97(12):128104. PMID: 17026003.
    Citations: 15     Fields:    Translation:Cells
  32. Viasnoff V, Meller A, Isambert H. DNA nanomechanical switches under folding kinetics control. . 2006 Jan; 6(1):101-4. PMID: 16402795.
    Citations: 8     Translation:Cells
  33. Sabanayagam CR, Eid JS, Meller A. Long time scale blinking kinetics of cyanine fluorophores conjugated to DNA and its effect on Förster resonance energy transfer. J Chem Phys. 2005 Dec 08; 123(22):224708. PMID: 16375496.
    Citations: 26     Fields:    Translation:Cells
  34. Mathé J, Aksimentiev A, Nelson DR, Schulten K, Meller A. Orientation discrimination of single-stranded DNA inside the alpha-hemolysin membrane channel. Proc Natl Acad Sci U S A. 2005 Aug 30; 102(35):12377-82. PMID: 16113083.
    Citations: 100     Fields:    Translation:Cells
  35. Sabanayagam CR, Eid JS, Meller A. Using fluorescence resonance energy transfer to measure distances along individual DNA molecules: corrections due to nonideal transfer. J Chem Phys. 2005 Feb 08; 122(6):061103. PMID: 15740360.
    Citations: 32     Fields:    Translation:Cells
  36. Mathé J, Visram H, Viasnoff V, Rabin Y, Meller A. Nanopore unzipping of individual DNA hairpin molecules. Biophys J. 2004 Nov; 87(5):3205-12. PMID: 15347593.
    Citations: 91     Fields:    Translation:Cells
  37. Bates M, Burns M, Meller A. Dynamics of DNA molecules in a membrane channel probed by active control techniques. Biophys J. 2003 Apr; 84(4):2366-72. PMID: 12668445.
    Citations: 38     Fields:    Translation:Cells
  38. Meller A, Branton D. Single molecule measurements of DNA transport through a nanopore. Electrophoresis. 2002 Aug; 23(16):2583-91. PMID: 12210161.
    Citations: 82     Fields:    Translation:Cells
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.