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Joost Michiel Riphagen, Ph.D.


Erasmus University, Rotterdam, The NetherlandsMD2006medicine
Maastricht university, Maastricht, The NetherlandsPhD2020Neuroscience
St Willibrord Spital, Emmerich Am Rhein, NRW Germany2015Anesthesia

I am a physician researcher (MD, Erasmus University Rotterdam, The Netherlands) with a background in Anesthesia and Critical care
(Residencies in The Netherlands (medicine, critical care) and Germany (anesthesia & critical care) with an interest in aging and dementia.
From 2015 to 2020 I was part of the Brain Aging aNd Dementia lab (Dr.David Salat) researching vascular contributions to dementias and
received my PhD in Neuroscience from the School for Mental Health and Neuroscience of Maastricht university (The Netherlands) in 2020.
I am currently part of the MGH Gordon Center for medical imaging (Dr. Georges El Fakhri), The Harvard Aging Brain Study (HABS) and the Bluespot/Heidi Jacobs Lab.(Dr. Heidi Jacobs)

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Riphagen JM, Suresh MB, Salat DH. The canonical pattern of Alzheimer's disease atrophy is linked to white matter hyperintensities in normal controls, differently in normal controls compared to in AD. Neurobiol Aging. 2022 06; 114:105-112. PMID: 35414420; PMCID: PMC9387174.
    Citations:    Fields:    Translation:Humans
  2. Jang I, Li B, Riphagen JM, Dickerson BC, Salat DH. Multiscale structural mapping of Alzheimer's disease neurodegeneration. Neuroimage Clin. 2022; 33:102948. PMID: 35121307; PMCID: PMC8814667.
    Citations:    Fields:    Translation:Humans
  3. Riphagen JM, van Hooren RWE, Kenis G, Verhey FRJ, Jacobs HIL. Distinct Patterns Link the BDNF Val66Met Polymorphism to Alzheimer's Disease Pathology. J Alzheimers Dis. 2022; 88(2):447-453. PMID: 35662115.
    Citations:    Fields:    Translation:Humans
  4. Li B, Jang I, Riphagen J, Almaktoum R, Yochim KM, Ances BM, Bookheimer SY, Salat DH. Identifying individuals with Alzheimer's disease-like brains based on structural imaging in the Human Connectome Project Aging cohort. Hum Brain Mapp. 2021 12 01; 42(17):5535-5546. PMID: 34582057; PMCID: PMC8559490.
    Citations: 1     Fields:    Translation:Humans
  5. Jung KH, Stephens KA, Yochim KM, Riphagen JM, Kim CM, Buckner RL, Salat DH. Heterogeneity of Cerebral White Matter Lesions and Clinical Correlates in Older Adults. Stroke. 2021 01; 52(2):620-630. PMID: 33406867; PMCID: PMC9477514.
    Citations: 4     Fields:    Translation:HumansCells
  6. Riphagen JM, van Egroo M, Jacobs HIL. Elevated Norepinephrine Metabolism Gauges Alzheimer's Disease-Related Pathology and Memory Decline. J Alzheimers Dis. 2021; 80(2):521-526. PMID: 33554915.
    Citations: 4     Fields:    Translation:Humans
  7. Li B, Zhang M, Riphagen J, Morrison Yochim K, Li B, Liu J, Salat DH. Prediction of clinical and biomarker conformed Alzheimer's disease and mild cognitive impairment from multi-feature brain structural MRI using age-correction from a large independent lifespan sample. Neuroimage Clin. 2020; 28:102387. PMID: 32871388; PMCID: PMC7476071.
    Citations: 1     Fields:    Translation:Humans
  8. Riphagen JM, Schmiedek L, Gronenschild EHBM, Yassa MA, Priovoulos N, Sack AT, Verhey FRJ, Jacobs HIL. Associations between pattern separation and hippocampal subfield structure and function vary along the lifespan: A 7?T imaging study. Sci Rep. 2020 05 05; 10(1):7572. PMID: 32371923.
    Citations: 2     Fields:    Translation:Humans
  9. Riphagen JM, Ramakers IHGM, Freeze WM, Pagen LHG, Hanseeuw BJ, Verbeek MM, Verhey FRJ, Jacobs HIL. Linking APOE-e4, blood-brain barrier dysfunction, and inflammation to Alzheimer's pathology. Neurobiol Aging. 2020 01; 85:96-103. PMID: 31733942.
    Citations: 15     Fields:    Translation:Humans
  10. Jacobs HIL, Riphagen JM, Ramakers IHGB, Verhey FRJ. Alzheimer's disease pathology: pathways between central norepinephrine activity, memory, and neuropsychiatric symptoms. Mol Psychiatry. 2021 03; 26(3):897-906. PMID: 31138892.
    Citations: 23     Fields:    Translation:Animals
  11. Van Hooren RWE, Riphagen JM, Jacobs HIL. Inter-network connectivity and amyloid-beta linked to cognitive decline in preclinical Alzheimer's disease: a longitudinal cohort study. Alzheimers Res Ther. 2018 08 28; 10(1):88. PMID: 30153858.
    Citations: 6     Fields:    Translation:Humans
  12. Riphagen JM, Gronenschild EHBM, Salat DH, Freeze WM, Ivanov D, Clerx L, Verhey FRJ, Aalten P, Jacobs HIL. Shades of white: diffusion properties of T1- and FLAIR-defined white matter signal abnormalities differ in stages from cognitively normal to dementia. Neurobiol Aging. 2018 08; 68:48-58. PMID: 29704648.
    Citations: 4     Fields:    Translation:Humans
  13. Müller-Ehrenberg L, Riphagen JM, Verhey FRJ, Sack AT, Jacobs HIL. Alzheimer's Disease Biomarkers Have Distinct Associations with Specific Hippocampal Subfield Volumes. J Alzheimers Dis. 2018; 66(2):811-823. PMID: 30320590.
    Citations: 3     Fields:    Translation:Humans
  14. Jacobs HI, Riphagen JM, Razat CM, Wiese S, Sack AT. Transcutaneous vagus nerve stimulation boosts associative memory in older individuals. Neurobiol Aging. 2015 May; 36(5):1860-7. PMID: 25805212.
    Citations: 53     Fields:    Translation:Humans
  15. Riphagen JM, van Neck JW, van Adrichem LN. 3D surface imaging in medicine: a review of working principles and implications for imaging the unsedated child. J Craniofac Surg. 2008 Mar; 19(2):517-24. PMID: 18362736.
    Citations: 1     Fields:    Translation:Humans
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.