Harvard Catalyst Profiles

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Meghan O'Melia, Ph.D.


Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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  1. Manspeaker MP, O'Melia MJ, Thomas SN. Elicitation of stem-like CD8+ T cell responses via lymph node-targeted chemoimmunotherapy evokes systemic tumor control. J Immunother Cancer. 2022 09; 10(9). PMID: 36100312; PMCID: PMC9472119.
    Citations: 1     Fields:    Translation:HumansAnimalsCells
  2. O'Melia MJ, Rohner NA, Thomas SN. Tumor Vascular Remodeling Affects Molecular Dissemination to Lymph Node and Systemic Leukocytes. Tissue Eng Part A. 2022 09; 28(17-18):781-794. PMID: 35442085; PMCID: PMC9508451.
    Citations:    Fields:    
  3. Kim J, Francis DM, Sestito LF, Archer PA, Manspeaker MP, O'Melia MJ, Thomas SN. Thermosensitive hydrogel releasing nitric oxide donor and anti-CTLA-4 micelles for anti-tumor immunotherapy. Nat Commun. 2022 03 18; 13(1):1479. PMID: 35304456; PMCID: PMC8933465.
    Citations: 2     Fields:    Translation:Humans
  4. O'Melia MJ, Mulero-Russe A, Kim J, Pybus A, DeRyckere D, Wood L, Graham DK, Botchwey E, García AJ, Thomas SN. Synthetic Matrix Scaffolds Engineer the In Vivo Tumor Immune Microenvironment for Immunotherapy Screening. Adv Mater. 2022 Mar; 34(10):e2108084. PMID: 34989049; PMCID: PMC8917077.
    Citations:    Fields:    Translation:HumansAnimals
  5. Archer PA, Sestito LF, Manspeaker MP, O'Melia MJ, Rohner NA, Schudel A, Mei Y, Thomas SN. Quantitation of lymphatic transport mechanism and barrier influences on lymph node-resident leukocyte access to lymph-borne macromolecules and drug delivery systems. Drug Deliv Transl Res. 2021 12; 11(6):2328-2343. PMID: 34165731; PMCID: PMC8571034.
    Citations: 1     Fields:    Translation:Cells
  6. O'Melia MJ, Manspeaker MP, Thomas SN. Tumor-draining lymph nodes are survival niches that support T cell priming against lymphatic transported tumor antigen and effects of immune checkpoint blockade in TNBC. Cancer Immunol Immunother. 2021 Aug; 70(8):2179-2195. PMID: 33459842; PMCID: PMC8286278.
    Citations: 4     Fields:    Translation:AnimalsCells
  7. O'Melia MJ, Rohner NA, Manspeaker MP, Francis DM, Kissick HT, Thomas SN. Quality of CD8+ T cell immunity evoked in lymph nodes is compartmentalized by route of antigen transport and functional in tumor context. Sci Adv. 2020 12; 6(50). PMID: 33310857; PMCID: PMC7732197.
    Citations: 6     Fields:    Translation:HumansCells
  8. Birmingham KG, O'Melia MJ, Bordy S, Reyes Aguilar D, El-Reyas B, Lesinski G, Thomas SN. Lymph Node Subcapsular Sinus Microenvironment-On-A-Chip Modeling Shear Flow Relevant to Lymphatic Metastasis and Immune Cell Homing. iScience. 2020 Nov 20; 23(11):101751. PMID: 33241198.
    Citations: 4     
  9. Francis DM, Manspeaker MP, Schudel A, Sestito LF, O'Melia MJ, Kissick HT, Pollack BP, Waller EK, Thomas SN. Blockade of immune checkpoints in lymph nodes through locoregional delivery augments cancer immunotherapy. Sci Transl Med. 2020 09 30; 12(563). PMID: 32998971.
    Citations: 41     Fields:    Translation:AnimalsCells
  10. Cermeño EA, O'Melia MJ, Han WM, Veith A, Barber G, Huang EH, Thomas SN, García AJ. Hydrodynamic shear-based purification of cancer cells with enhanced tumorigenic potential. Integr Biol (Camb). 2020 02 22; 12(1):1-11. PMID: 31965190.
    Citations:    Fields:    Translation:HumansAnimalsCells
  11. O'Melia MJ, Lund AW, Thomas SN. The Biophysics of Lymphatic Transport: Engineering Tools and Immunological Consequences. iScience. 2019 Dec 20; 22:28-43. PMID: 31739172.
    Citations: 9     
  12. Birmingham KG, O'Melia MJ, Ban D, Mouw J, Edwards EE, Marcus AI, McDonald J, Thomas SN. Analyzing Mechanisms of Metastatic Cancer Cell Adhesive Phenotype Leveraging Preparative Adhesion Chromatography Microfluidic. Adv Biosyst. 2019 03; 3(3):e1800328. PMID: 32627398.
    Citations: 2     Fields:    Translation:HumansAnimalsCells
  13. Edwards EE, Birmingham KG, O'Melia MJ, Oh J, Thomas SN. Fluorometric Quantification of Single-Cell Velocities to Investigate Cancer Metastasis. Cell Syst. 2018 11 28; 7(5):496-509.e6. PMID: 30414924.
    Citations: 7     Fields:    Translation:HumansCells
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.