Harvard Catalyst Profiles

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Taylor A. Burke, Ph.D.

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Biography
Alpert Medical School of Brown University, Providence, RIClinical Psychology Postdoctoral Fellowship03/2021Child Clinical Psychology
Alpert Medical School of Brown University, Providence, RIClinical Psychology Internship07/2019Child Clinical Psychology
Temple University, Philadelphia, PAPhD08/2019Clinical Psychology
Duke University, Durham,NCBA05/2011Psychology & Philosophy

Overview

Research
The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
  1. R21MH127231 (BURKE, TAYLOR A) Sep 1, 2021 - Aug 31, 2023
    NIH
    Leveraging Computer Vision to Augment Suicide Risk Prediction
    Role: Principal Investigator
  2. K23MH126168 (BURKE, TAYLOR A) Apr 1, 2021 - Mar 31, 2026
    NIH
    Passive Assessment of Behavioral Warning Signs for Suicide Risk in Adolescents: An Idiographic Approach
    Role: Principal Investigator

Bibliographic
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Nesi J, Burke TA, Caltabiano A, Spirito A, Wolff JC. Digital media-related precursors to psychiatric hospitalization among youth. J Affect Disord. 2022 May 06; 310:235-240. PMID: 35533775.
    Citations:    Fields:    
  2. Burke TA, Hamilton JL, Seigel D, Kautz M, Liu RT, Alloy LB, Barker DH. Sleep Irregularity and Nonsuicidal Self-injurious Urges and Behaviors. Sleep. 2022 Apr 09. PMID: 35397476.
    Citations:    Fields:    
  3. Allen KJD, Johnson SL, Burke TA, Sammon MM, Wu C, Kramer MA, Wu J, Schatten HT, Armey MF, Hooley JM. Validation of an emotional stop-signal task to probe individual differences in emotional response inhibition: Relationships with positive and negative urgency. Brain Neurosci Adv. 2021 Jan-Dec; 5:23982128211058269. PMID: 34841088.
    Citations: 1     
  4. Fox KR, Bettis AH, Burke TA, Hart EA, Wang SB. Exploring Adolescent Experiences with Disclosing Self-Injurious Thoughts and Behaviors Across Settings. Res Child Adolesc Psychopathol. 2022 May; 50(5):669-681. PMID: 34705197.
    Citations:    Fields:    Translation:Humans
  5. Nesi J, Burke TA, Extein J, Kudinova AY, Fox KA, Hunt J, Wolff JC. Social media use, sleep, and psychopathology in psychiatrically hospitalized adolescents. J Psychiatr Res. 2021 12; 144:296-303. PMID: 34710666.
    Citations:    Fields:    Translation:Humans
  6. Lawrence HR, Burke TA, Sheehan AE, Pastro B, Levin RY, Walsh RFL, Bettis AH, Liu RT. Prevalence and correlates of suicidal ideation and suicide attempts in preadolescent children: A US population-based study. Transl Psychiatry. 2021 09 22; 11(1):489. PMID: 34552053.
    Citations:    Fields:    Translation:Humans
  7. Burke TA, Shao S, Jacobucci R, Kautz M, Alloy LB, Ammerman BA. Examining momentary associations between behavioral approach system indices and nonsuicidal self-injury urges. J Affect Disord. 2022 01 01; 296:244-249. PMID: 34619451.
    Citations:    Fields:    Translation:Humans
  8. Ammerman BA, Burke TA, Jacobucci R, McClure K. How we ask matters: The impact of question wording in single-item measurement of suicidal thoughts and behaviors. Prev Med. 2021 11; 152(Pt 1):106472. PMID: 34538365.
    Citations: 1     Fields:    Translation:Humans
  9. Burke TA, Bettis AH, Barnicle SC, Wang SB, Fox KR. Disclosure of Self-Injurious Thoughts and Behaviors Across Sexual and Gender Identities. Pediatrics. 2021 10; 148(4). PMID: 34521728.
    Citations:    Fields:    Translation:Humans
  10. Liu RT, Lawrence HR, Burke TA, Sanzari CM, Levin RY, Maitlin C, Paszek C, Zhu X. Passive and active suicidal ideation among left-behind children in rural China: An evaluation of intrapersonal and interpersonal vulnerability and resilience. Suicide Life Threat Behav. 2021 12; 51(6):1213-1223. PMID: 34514644.
    Citations:    Fields:    Translation:Humans
  11. Burke TA, Bettis AH, Kudinova A, Thomas SA, Nesi J, Erguder L, MacPherson HA, Thompson E, Ammerman BA, Wolff JC. COVID-19-Specific Suicidal Thoughts and Behaviors in Psychiatrically Hospitalized Adolescents. Child Psychiatry Hum Dev. 2021 Aug 06. PMID: 34357502.
    Citations:    Fields:    
  12. Lawrence HR, Nesi J, Burke TA, Liu RT, Spirito A, Hunt J, Wolff JC. Correction to: Suicidal Mental Imagery in Psychiatrically Hospitalized Adolescents. Res Child Adolesc Psychopathol. 2021 Aug; 49(8):1111. PMID: 34043131.
    Citations:    Fields:    
  13. Kudinova AY, Bettis AH, Thompson EC, Thomas SA, Nesi J, Erguder L, MacPherson HA, Burke TA, Wolff JC. COVID-19 Related Daily Stressors, Coping, and Suicidal Ideation in Psychiatrically Hospitalized Youth. Child Youth Care Forum. 2022; 51(3):579-592. PMID: 34305371.
    Citations: 1     
  14. Ammerman BA, Burke TA, McClure K, Jacobucci R, Liu RT. A prospective examination of COVID-19-related social distancing practices on suicidal ideation. Suicide Life Threat Behav. 2021 10; 51(5):969-977. PMID: 34184290.
    Citations: 1     Fields:    Translation:HumansCellsPHPublic Health
  15. Bettis AH, Burke TA, Nesi J, Liu RT. Digital Technologies for Emotion-Regulation Assessment and Intervention: A Conceptual Review. Clin Psychol Sci. 2022 Jan; 10(1):3-26. PMID: 35174006.
    Citations:    
  16. Burke TA, Kutok ER, Dunsiger S, Nugent NR, Patena JV, Riese A, Ranney ML. A national snapshot of U.S. adolescents' mental health and changing technology use during COVID-19. Gen Hosp Psychiatry. 2021 Jul-Aug; 71:147-148. PMID: 34090695.
    Citations: 1     Fields:    Translation:HumansCells
  17. Nesi J, Burke TA, Bettis AH, Kudinova AY, Thompson EC, MacPherson HA, Fox KA, Lawrence HR, Thomas SA, Wolff JC, Altemus MK, Soriano S, Liu RT. Social media use and self-injurious thoughts and behaviors: A systematic review and meta-analysis. Clin Psychol Rev. 2021 07; 87:102038. PMID: 34034038.
    Citations: 1     Fields:    Translation:Humans
  18. Burke TA, Allen KJD, Carpenter RW, Siegel DM, Kautz MM, Liu RT, Alloy LB. Emotional response inhibition to self-harm stimuli interacts with momentary negative affect to predict nonsuicidal self-injury urges. Behav Res Ther. 2021 07; 142:103865. PMID: 33940222.
    Citations: 3     Fields:    Translation:Humans
  19. Thompson EC, Thomas SA, Burke TA, Nesi J, MacPherson HA, Bettis AH, Kudinova AY, Affleck K, Hunt J, Wolff JC. Suicidal thoughts and behaviors in psychiatrically hospitalized adolescents pre- and post- COVID-19: A historical chart review and examination of contextual correlates. J Affect Disord Rep. 2021 Apr; 4:100100. PMID: 33558865.
    Citations: 11     
  20. Nesi J, Burke TA, Lawrence HR, MacPherson HA, Spirito A, Wolff JC. Online Self-Injury Activities among Psychiatrically Hospitalized Adolescents: Prevalence, Functions, and Perceived Consequences. Res Child Adolesc Psychopathol. 2021 04; 49(4):519-531. PMID: 33404950.
    Citations: 1     Fields:    Translation:Humans
  21. Lawrence HR, Nesi J, Burke TA, Liu RT, Spirito A, Hunt J, Wolff JC. Suicidal Mental Imagery in Psychiatrically Hospitalized Adolescents. Res Child Adolesc Psychopathol. 2021 03; 49(3):393-399. PMID: 33403495.
    Citations:    Fields:    Translation:Humans
  22. Ammerman BA, Burke TA, Jacobucci R, McClure K. Preliminary investigation of the association between COVID-19 and suicidal thoughts and behaviors in the U.S. J Psychiatr Res. 2021 02; 134:32-38. PMID: 33360222.
    Citations: 33     Fields:    Translation:HumansCellsPHPublic Health
  23. Burke TA, Fox K, Kautz M, Siegel DM, Kleiman E, Alloy LB. Real-time monitoring of the associations between self-critical and self-punishment cognitions and nonsuicidal self-injury. Behav Res Ther. 2021 02; 137:103775. PMID: 33421892.
    Citations: 2     Fields:    Translation:Humans
  24. Kautz MM, Burke TA, Siegel DM, Case J, Alloy LB. The role of reward sensitivity and childhood maltreatment in predicting nonsuicidal self-injury. Suicide Life Threat Behav. 2020 12; 50(6):1250-1263. PMID: 33135809.
    Citations: 1     Fields:    Translation:Humans
  25. Burke TA, Fox K, Kautz MM, Rodriguez-Seijas C, Bettis AH, Alloy LB. Self-Critical and Self-Punishment Cognitions Differentiate Those With and Without a History of Nonsuicidal Self-Injury: An Ecological Momentary Assessment Study. Behav Ther. 2021 05; 52(3):686-697. PMID: 33990242.
    Citations: 1     Fields:    Translation:Humans
  26. O'Loughlin C, Burke TA, Ammerman BA. Examining the Time to Transition From Nonsuicidal Self-Injury to Suicide Attempt. Crisis. 2021 Mar; 42(2):157-161. PMID: 32845177.
    Citations: 1     Fields:    Translation:Humans
  27. Bettis AH, Thompson EC, Burke TA, Nesi J, Kudinova AY, Hunt JI, Liu RT, Wolff JC. Prevalence and clinical indices of risk for sexual and gender minority youth in an adolescent inpatient sample. J Psychiatr Res. 2020 11; 130:327-332. PMID: 32877826.
    Citations: 4     Fields:    Translation:Humans
  28. Titone MK, McArthur BA, Ng TH, Burke TA, McLaughlin LE, MacMullen LE, Goel N, Alloy LB. Sex and race influence objective and self-report sleep and circadian measures in emerging adults independently of risk for bipolar spectrum disorder. Sci Rep. 2020 08 13; 10(1):13731. PMID: 32792642.
    Citations: 3     Fields:    Translation:Humans
  29. Liu RT, Steele SJ, Hamilton JL, Do QBP, Furbish K, Burke TA, Martinez AP, Gerlus N. Sleep and suicide: A systematic review and meta-analysis of longitudinal studies. Clin Psychol Rev. 2020 11; 81:101895. PMID: 32801085.
    Citations: 6     Fields:    Translation:Humans
  30. Burke TA, Ammerman BA, Hamilton JL, Stange JP, Piccirillo M. Nonsuicidal self-injury scar concealment from the self and others. J Psychiatr Res. 2020 11; 130:313-320. PMID: 32871456.
    Citations: 1     Fields:    Translation:Humans
  31. Burke TA, Nesi J, Domoff SE, Romanowicz M, Croarkin PE. Titrating Social Media Use During Adolescent Inpatient Psychiatric Hospitalization. J Am Acad Child Adolesc Psychiatry. 2020 09; 59(9):1007-1009. PMID: 32615152.
    Citations: 1     Fields:    Translation:Humans
  32. Piccirillo ML, Burke TA, Moore-Berg SL, Alloy LB, Heimberg RG. Self-Stigma Toward Nonsuicidal Self-Injury: An Examination of Implicit and Explicit Attitudes. Suicide Life Threat Behav. 2020 10; 50(5):1007-1024. PMID: 32462657.
    Citations:    Fields:    Translation:Humans
  33. Burke TA, Jacobucci R, Ammerman BA, Alloy LB, Diamond G. Using machine learning to classify suicide attempt history among youth in medical care settings. J Affect Disord. 2020 05 01; 268:206-214. PMID: 32174479.
    Citations: 1     Fields:    Translation:Humans
  34. Liu RT, Bettis AH, Burke TA. Characterizing the phenomenology of passive suicidal ideation: a systematic review and meta-analysis of its prevalence, psychiatric comorbidity, correlates, and comparisons with active suicidal ideation. Psychol Med. 2020 02; 50(3):367-383. PMID: 31907085.
    Citations: 12     Fields:    Translation:Humans
  35. Hamilton JL, Stange JP, Burke TA, Franzen PL, Alloy LB. Sleep disturbance and physiological regulation among young adults with prior depression. J Psychiatr Res. 2019 08; 115:75-81. PMID: 31121395.
    Citations: 4     Fields:    Translation:Humans
  36. Case JAC, Burke TA, Siegel DM, Piccirillo ML, Alloy LB, Olino TM. Functions of Non-Suicidal Self-Injury in Late Adolescence: A Latent Class Analysis. Arch Suicide Res. 2020; 24(sup2):S165-S186. PMID: 30856362.
    Citations: 4     Fields:    Translation:Humans
  37. McArthur BA, Burke TA, Connolly SL, Olino TM, Lumley MN, Abramson LY, Alloy LB. A Longitudinal Investigation of Cognitive Self-schemas across Adolescent Development. J Youth Adolesc. 2019 Mar; 48(3):635-647. PMID: 30612293.
    Citations: 3     Fields:    Translation:Humans
  38. Liu RT, McArthur BA, Burke TA, Hamilton JL, Mac Giollabhui N, Stange JP, Hamlat EJ, Abramson LY, Alloy LB. A Latent Structure Analysis of Cognitive Vulnerability to Depression in Adolescence. Behav Ther. 2019 07; 50(4):755-764. PMID: 31208685.
    Citations: 2     Fields:    Translation:Humans
  39. Burke TA, Fox K, Zelkowitz RL, Smith DMY, Alloy LB, Hooley JM, Cole DA. Does nonsuicidal self-injury prospectively predict change in depression and self-criticism? Cognit Ther Res. 2019 Apr; 43(2):345-353. PMID: 33162625.
    Citations: 1     
  40. Burke TA, Ammerman BA, Jacobucci R. The use of machine learning in the study of suicidal and non-suicidal self-injurious thoughts and behaviors: A systematic review. J Affect Disord. 2019 02 15; 245:869-884. PMID: 30699872.
    Citations: 25     Fields:    Translation:Humans
  41. Burke TA, Piccirillo ML, Moore-Berg SL, Alloy LB, Heimberg RG. The stigmatization of nonsuicidal self-injury. J Clin Psychol. 2019 03; 75(3):481-498. PMID: 30368804.
    Citations: 9     Fields:    Translation:Humans
  42. Ammerman BA, Serang S, Jacobucci R, Burke TA, Alloy LB, McCloskey MS. Exploratory analysis of mediators of the relationship between childhood maltreatment and suicidal behavior. J Adolesc. 2018 12; 69:103-112. PMID: 30286328.
    Citations: 1     Fields:    Translation:Humans
  43. Liu RT, Burke TA, Abramson LY, Alloy LB. The Behavioral Approach System (BAS) Model of Vulnerability to Bipolar Disorder: Evidence of a Continuum in BAS Sensitivity across Adolescence. J Abnorm Child Psychol. 2018 08; 46(6):1333-1349. PMID: 29101589.
    Citations: 1     Fields:    Translation:Humans
  44. Crawford EA, Burke TA, Siegel D, Jager-Hyman S, Alloy LB, Kendall PC. Somatic Symptoms of Anxiety and Suicide Ideation Among Treatment-Seeking Youth With Anxiety Disorders. Suicide Life Threat Behav. 2019 06; 49(3):811-825. PMID: 29900567.
    Citations: 2     Fields:    Translation:Humans
  45. McArthur BA, Haas LM, Burke TA, Johnson LE, Olino TM, Abramson LY, Alloy LB. Understanding the Constellation of Adolescent Emotional Clarity and Cognitive Response Styles when Predicting Depression: A Latent Class Analysis. Cognit Ther Res. 2018; 42:803-812. PMID: 33223584.
    Citations: 1     
  46. Siegel DM, Burke TA, Hamilton JL, Piccirillo ML, Scharff A, Alloy LB. Social anxiety and interpersonal stress generation: the moderating role of interpersonal distress. Anxiety Stress Coping. 2018 Sep; 31(5):526-538. PMID: 29855206.
    Citations: 2     Fields:    Translation:Humans
  47. Haas LM, McArthur BA, Burke TA, Olino TM, Abramson LY, Alloy LB. Emotional clarity development and psychosocial outcomes during adolescence. Emotion. 2019 Jun; 19(4):563-572. PMID: 29781646.
    Citations: 4     Fields:    Translation:Humans
  48. Burke TA, Jacobucci R, Ammerman BA, Piccirillo M, McCloskey MS, Heimberg RG, Alloy LB. Identifying the relative importance of non-suicidal self-injury features in classifying suicidal ideation, plans, and behavior using exploratory data mining. Psychiatry Res. 2018 04; 262:175-183. PMID: 29453036.
    Citations: 12     Fields:    Translation:Humans
  49. Burke TA, Anne McArthur B, Daryanani I, Abramson LY, Alloy LB. Latent classes of trait affect and cognitive affective regulation strategies are associated with depression, non-suicidal self-injury, and well-being. J Affect Disord. 2018 01 01; 225:180-187. PMID: 28837951.
    Citations: 6     Fields:    Translation:Humans
  50. Ng TH, Burke TA, Stange JP, Walshaw PD, Weiss RB, Urosevic S, Abramson LY, Alloy LB. Personality disorder symptom severity predicts onset of mood episodes and conversion to bipolar I disorder in individuals with bipolar spectrum disorder. J Abnorm Psychol. 2017 Apr; 126(3):271-284. PMID: 28368159.
    Citations: 1     Fields:    Translation:Humans
  51. Burke TA, Ammerman BA, Knorr AC, Alloy LB, McCloskey MS. Measuring Acquired Capability for Suicide within an Ideation-to-Action Framework. Psychol Violence. 2018 Mar; 8(2):277-286. PMID: 29732237.
    Citations: 6     
  52. Burke TA, Olino TM, Alloy LB. Initial Psychometric Validation of the Non-Suicidal Self-Injury Scar Cognition Scale. J Psychopathol Behav Assess. 2017 Sep; 39(3):546-562. PMID: 28824225.
    Citations: 2     
  53. Hamilton JL, Burke TA, Stange JP, Kleiman EM, Rubenstein LM, Scopelliti KA, Abramson LY, Alloy LB. Trait Affect, Emotion Regulation, and the Generation of Negative and Positive Interpersonal Events. Behav Ther. 2017 07; 48(4):435-447. PMID: 28577581.
    Citations: 7     Fields:    Translation:Humans
  54. Shapero BG, Weiss RB, Burke TA, Boland EM, Abramson LY, Alloy LB. Kindling of Life Stress in Bipolar Disorder: Effects of Early Adversity. Behav Ther. 2017 05; 48(3):322-334. PMID: 28390496.
    Citations: 7     Fields:    Translation:Humans
  55. Burke TA, Ammerman BA, Hamilton JL, Alloy LB. Impact of Non-Suicidal Self-Injury Scale: Initial Psychometric Validation. Cognit Ther Res. 2017 Feb; 41(1):130-142. PMID: 28824214.
    Citations: 2     
  56. Burke TA, Connolly SL, Hamilton JL, Stange JP, Abramson LY, Alloy LB. Cognitive Risk and Protective Factors for Suicidal Ideation: A Two Year Longitudinal Study in Adolescence. J Abnorm Child Psychol. 2016 08; 44(6):1145-60. PMID: 26597963.
    Citations: 24     Fields:    Translation:Humans
  57. Burke TA, Hamilton JL, Ammerman BA, Stange JP, Alloy LB. Suicide risk characteristics among aborted, interrupted, and actual suicide attempters. Psychiatry Res. 2016 Aug 30; 242:357-364. PMID: 27344029.
    Citations: 4     Fields:    Translation:Humans
  58. Stange JP, Connolly SL, Burke TA, Hamilton JL, Hamlat EJ, Abramson LY, Alloy LB. INFLEXIBLE COGNITION PREDICTS FIRST ONSET OF MAJOR DEPRESSIVE EPISODES IN ADOLESCENCE. Depress Anxiety. 2016 Nov; 33(11):1005-1012. PMID: 27093215.
    Citations: 29     Fields:    
  59. Burke TA, Alloy LB. Moving Toward an Ideation-to-Action Framework in Suicide Research: A Commentary on. Clin Psychol (New York). 2016 Mar; 23(1):26-30. PMID: 28111500.
    Citations: 5     Fields:    
  60. Ammerman BA, Burke TA, Alloy LB, McCloskey MS. Subjective pain during NSSI as an active agent in suicide risk. Psychiatry Res. 2016 Feb 28; 236:80-85. PMID: 26747213.
    Citations: 7     Fields:    Translation:Humans
  61. Burke TA, Hamilton JL, Cohen JN, Stange JP, Alloy LB. Identifying a physical indicator of suicide risk: Non-suicidal self-injury scars predict suicidal ideation and suicide attempts. Compr Psychiatry. 2016 Feb; 65:79-87. PMID: 26773994.
    Citations: 6     Fields:    Translation:Humans
  62. Burke TA, Hamilton JL, Abramson LY, Alloy LB. Non-suicidal self-injury prospectively predicts interpersonal stressful life events and depressive symptoms among adolescent girls. Psychiatry Res. 2015 Aug 30; 228(3):416-24. PMID: 26165966.
    Citations: 21     Fields:    Translation:Humans
  63. Stange JP, Hamilton JL, Burke TA, Kleiman EM, O'Garro-Moore JK, Seligman ND, Abramson LY, Alloy LB. Negative cognitive styles synergistically predict suicidal ideation in bipolar spectrum disorders: a 3-year prospective study. Psychiatry Res. 2015 Mar 30; 226(1):162-8. PMID: 25660736.
    Citations: 10     Fields:    Translation:Humans
  64. Daryanani I, Hamilton JL, Shapero BG, Burke TA, Abramson LY, Alloy LB. Differential Reporting of Adolescent Stress as a Function of Maternal Depression History. Cognit Ther Res. 2015; 39(2):110-119. PMID: 25798018.
    Citations: 4     
  65. Burke TA, Stange JP, Hamilton JL, Cohen JN, O'Garro-Moore J, Daryanani I, Abramson LY, Alloy LB. Cognitive and Emotion-Regulatory Mediators of the Relationship Between Behavioral Approach System Sensitivity and Nonsuicidal Self-Injury Frequency. Suicide Life Threat Behav. 2015 Aug; 45(4):495-504. PMID: 25443691.
    Citations: 14     Fields:    Translation:Humans
  66. Cohen JN, Stange JP, Hamilton JL, Burke TA, Jenkins A, Ong ML, Heimberg RG, Abramson LY, Alloy LB. The interaction of affective states and cognitive vulnerabilities in the prediction of non-suicidal self-injury. Cogn Emot. 2015; 29(3):539-47. PMID: 24853872.
    Citations: 7     Fields:    Translation:Humans
  67. Wolff JC, Frazier EA, Esposito-Smythers C, Becker SJ, Burke TA, Cataldo A, Spirito A. Negative cognitive style and perceived social support mediate the relationship between aggression and NSSI in hospitalized adolescents. J Adolesc. 2014 Jun; 37(4):483-91. PMID: 24793396.
    Citations: 6     Fields:    Translation:Humans
  68. Wolff J, Frazier EA, Esposito-Smythers C, Burke T, Sloan E, Spirito A. Cognitive and social factors associated with NSSI and suicide attempts in psychiatrically hospitalized adolescents. J Abnorm Child Psychol. 2013 Aug; 41(6):1005-13. PMID: 23588400.
    Citations: 11     Fields:    Translation:Humans
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.