Harvard Catalyst Profiles

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Farhad Nezami, Ph.D.

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Biography
MIT, Cambridge, MAPostdoc12/2020Medical Engineering
ETH Zurich, SwitzerlandPhD10/2013Mechanical Engineering
2021
Pillars of Excellence Award
2021
SPOT Award
2023 - 2024
IGNITE Award
2023 - 2025
Critical care & Resuscitation Award
2024 - 2025
Katelyn M. Caruso & Rapid AI Chairs of Research
2024
Mentorship Award
2024
Pillars of Excellence Award

Overview
Nezami Lab at Brigham and Women’s Hospital is where cutting-edge computational tools meet translational medicine to revolutionize cardiovascular care. Our team integrates mechanics, bioinformatics, and state-of-the-art engineering to uncover the mechanistic roots of critical valvular and vascular diseases while pioneering novel therapies. Combining in silico modeling with in vitro and in vivo experimentation, we advance precision medicine and medical device innovation. From optimizing prosthetic valves and life support systems to harnessing AI for surgery and diagnostics, our lab spans a dynamic spectrum of cardiovascular applications. Leveraging collaborations with BWH’s pioneering clinicians and unique access to clinical trials, we build robust data-driven tools for risk stratification, predictive modeling, and informed surgical decisions in cardiac surgery and intervention. At the Nezami Lab, we strive to bridge science and patient care, fostering collaboration with clinical experts and industry partners to translate discoveries into lifesaving outcomes.

Research
The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
  1. N660012424024 (Steve Keller) Sep 1, 2024 - Feb 28, 2027
    DARPA
    IRON MAN - Innovative Resuscitation and Optimized Novel Multi-organ support with Autonomous ecmo for Non-medical personnel and medics
    Role: Site PI
  2. R21HL173731 (RIKHTEGAR NEZAMI, FARHAD) Sep 1, 2024 - Aug 31, 2026
    NIH
    Leveraging Sexual Dimorphism to Predict Cardiac Remodeling and Enhance Treatment in Women with Severe Aortic Stenosis
    Role: Principal Investigator
  3. 5R01HL161069-02 (EDELMAN, ELAZER R) Jan 1, 2022 - Dec 31, 2025
    NIH
    Personalized lesion modification optimizes atherosclerosis intervention
    Role: Co-Investigator

Featured Content

Bibliographic
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.