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Noriyuki Okonogi, Ph.D., M.D.


Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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  1. Onishi M, Kawamura H, Murata K, Inoue T, Murata H, Takakusagi Y, Okonogi N, Ohkubo Y, Okamoto M, Kaminuma T, Sekihara T, Nakano T, Ohno T. Intensity-Modulated Radiation Therapy with Simultaneous Integrated Boost for Clinically Node-Positive Prostate Cancer: A Single-Institutional Retrospective Study. Cancers (Basel). 2021 Jul 31; 13(15). PMID: 34359768.
  2. Murakami N, Ando K, Murata M, Murata K, Ohno T, Aoshika T, Kato S, Okonogi N, Saito AI, Kim JY, Kumai Y, Yoshioka Y, Sekii S, Tsujino K, Lowanichkiattikul C, Pattaranutaporn P, Kaneyasu Y, Nakagawa T, Watanabe M, Uno T, Umezawa R, Jingu K, Kanemoto A, Wakatsuki M, Shirai K, Igaki H, Itami J. Why not de-intensification for uterine cervical cancer? Gynecol Oncol. 2021 Jul 19. PMID: 34294413.
    Citations:    Fields:    
  3. Okonogi N, Ando K, Murata K, Wakatsuki M, Noda SE, Irie D, Tsuji H, Shozu M, Ohno T. Multi-Institutional Retrospective Analysis of Carbon-Ion Radiotherapy for Patients with Locally Advanced Adenocarcinoma of the Uterine Cervix. Cancers (Basel). 2021 May 31; 13(11). PMID: 34072676.
  4. Otani Y, Ohno T, Ando K, Murata K, Kato S, Noda SE, Murofushi K, Ushijima H, Yoshida D, Okonogi N, Isohashi F, Wakatsuki M, Nakano T. Dosimetric feasibility of computed tomography-based image-guided brachytherapy in locally advanced cervical cancer: a Japanese prospective multi-institutional study. J Radiat Res. 2021 May 12; 62(3):502-510. PMID: 33532828.
    Citations:    Fields:    
  5. Mori Y, Sato H, Kumazawa T, Permata TBM, Yoshimoto Y, Murata K, Noda SE, Kaminuma T, Ando K, Oike T, Okonogi N, Okada K, Kakoti S, Suzuki K, Ikota H, Yokoo H, Nakano T, Ohno T, Shibata A. Analysis of radiotherapy-induced alteration of CD8+ T cells and PD-L1 expression in patients with uterine cervical squamous cell carcinoma. Oncol Lett. 2021 Jun; 21(6):446. PMID: 33868484.
  6. Miyasaka Y, Okonogi N, Fukahori M, Furuichi W, Wakatsuki M, Kato S, Ohno T, Nakano T, Tsuji H. Pelvic insufficiency fractures following carbon-ion radiotherapy for uterine carcinomas. Radiother Oncol. 2021 03; 156:56-61. PMID: 33278405.
    Citations:    Fields:    Translation:Humans
  7. Matsumoto S, Lee SH, Imai R, Inaniwa T, Matsufuji N, Fukahori M, Kohno R, Yonai S, Okonogi N, Yamada S, Kanematsu N. Unresectable Chondrosarcomas Treated With Carbon Ion Radiotherapy: Relationship Between Dose-averaged Linear Energy Transfer and Local Recurrence. Anticancer Res. 2020 Nov; 40(11):6429-6435. PMID: 33109581.
    Citations:    Fields:    Translation:HumansCells
  8. Okonogi N, Matsumoto S, Fukahori M, Furuichi W, Inaniwa T, Matsufuji N, Imai R, Yamada S, Kanematsu N, Tsuji H. Dose-averaged linear energy transfer per se does not correlate with late rectal complications in carbon-ion radiotherapy. Radiother Oncol. 2020 12; 153:272-278. PMID: 32898559.
    Citations: 1     Fields:    Translation:HumansCells
  9. Okonogi N, Wakatsuki M, Mizuno H, Fukuda S, Cao J, Kodrat H, Lau FN, Calaguas MJ, de Los Reyes RH, Chansilpa Y, Uddin AFMK, Adylkhanov T, Cho CK, Tsegmed U, Hoang NC, Ohno T, Nakano T, Kato S. Preliminary survey of 3D image-guided brachytherapy for cervical cancer at representative hospitals in Asian countries. J Radiat Res. 2020 Jul 06; 61(4):608-615. PMID: 32367130.
    Citations:    Fields:    Translation:Humans
  10. Sato H, Okonogi N, Nakano T. Rationale of combination of anti-PD-1/PD-L1 antibody therapy and radiotherapy for cancer treatment. Int J Clin Oncol. 2020 May; 25(5):801-809. PMID: 32246277.
    Citations: 20     Fields:    Translation:HumansAnimals
  11. Miyasaka Y, Yoshimoto Y, Murata K, Noda SE, Ando K, Ebara T, Okonogi N, Kaminuma T, Yamada S, Ikota H, Yokoo H, Ohno T, Nakano T. Treatment outcomes of patients with adenocarcinoma of the uterine cervix after definitive radiotherapy and the prognostic impact of tumor-infiltrating CD8+ lymphocytes in pre-treatment biopsy specimens: a multi-institutional retrospective study. J Radiat Res. 2020 Mar 23; 61(2):275-284. PMID: 32052042.
    Citations: 7     Fields:    Translation:HumansCells
  12. Applegate KE, Rühm W, Wojcik A, Bourguignon M, Brenner A, Hamasaki K, Imai T, Imaizumi M, Imaoka T, Kakinuma S, Kamada T, Nishimura N, Okonogi N, Ozasa K, Rübe CE, Sadakane A, Sakata R, Shimada Y, Yoshida K, Bouffler S. Individual response of humans to ionising radiation: governing factors and importance for radiological protection. Radiat Environ Biophys. 2020 05; 59(2):185-209. PMID: 32146555.
    Citations: 1     Fields:    Translation:HumansAnimals
  13. Okonogi N, Wakatsuki M, Kato S, Murata H, Kiyohara H, Karasawa K, Ohno T, Tsuji H, Nakano T, Shozu M. Significance of concurrent use of weekly cisplatin in carbon-ion radiotherapy for locally advanced adenocarcinoma of the uterine cervix: A propensity score-matched analysis. Cancer Med. 2020 02; 9(4):1400-1408. PMID: 31891228.
    Citations: 2     Fields:    Translation:Humans
  14. Iijima M, Okonogi N, Nakajima NI, Morokoshi Y, Kanda H, Yamada T, Kobayashi Y, Banno K, Wakatsuki M, Yamada S, Kamada T, Aoki D, Hasegawa S. Significance of PD-L1 expression in carbon-ion radiotherapy for uterine cervical adeno/adenosquamous carcinoma. J Gynecol Oncol. 2020 Mar; 31(2):e19. PMID: 31912675.
    Citations: 9     Fields:    Translation:HumansCells
  15. Darwis NDM, Nachankar A, Sasaki Y, Matsui T, Noda SE, Murata K, Tamaki T, Ando K, Okonogi N, Shiba S, Irie D, Kaminuma T, Kumazawa T, Anakura M, Yamashita S, Hirakawa T, Kakoti S, Hirota Y, Tokino T, Iwase A, Ohno T, Shibata A, Oike T, Nakano T. FGFR Signaling as a Candidate Therapeutic Target for Cancers Resistant to Carbon Ion Radiotherapy. Int J Mol Sci. 2019 Sep 14; 20(18). PMID: 31540114.
    Citations: 4     Fields:    Translation:HumansCells
  16. Kobayashi D, Okonogi N, Wakatsuki M, Miyasaka Y, Kiyohara H, Ohno T, Kato S, Nakano T, Kamada T. Impact of CT-based brachytherapy in elderly patients with cervical cancer. Brachytherapy. 2019 Nov - Dec; 18(6):771-779. PMID: 31506225.
    Citations: 2     Fields:    Translation:Humans
  17. Wakatsuki M, Kato S, Ohno T, Banu PA, Hoang NC, Yadamsuren E, Supriana N, Cao J, Devi CRB, Calaguas MJ, Chansilpa Y, Cho CK, Adylkhanov T, Okonogi N, Nakano T, Tsujii H. Multi-institutional Observational Study of Prophylactic Extended-Field Concurrent Chemoradiation Therapy Using Weekly Cisplatin for Patients With Pelvic Node-Positive Cervical Cancer in East and Southeast Asia. Int J Radiat Oncol Biol Phys. 2019 09 01; 105(1):183-189. PMID: 31125594.
    Citations: 1     Fields:    Translation:Humans
  18. Okonogi N, Suzuki Y, Sato H, Oike T, Yoshimoto Y, Mimura K, Noda SE, Okamoto M, Tamaki T, Morokoshi Y, Hasegawa S, Ohgaki H, Yokoo H, Nakano T. In Reply to Minhas and Tran. Int J Radiat Oncol Biol Phys. 2019 05 01; 104(1):223-224. PMID: 30967232.
    Citations:    Fields:    Translation:AnimalsCells
  19. Sato H, Okonogi N, Yoshimoto Y, Tamaki T, Suzuki Y. [Radiotherapy and PD-L1 Expression]. Gan To Kagaku Ryoho. 2019 May; 46(5):845-849. PMID: 31189801.
    Citations: 3     Fields:    Translation:HumansCells
  20. Okonogi N, Kaminuma T, Okimoto T, Shinoto M, Yamamoto N, Yamada S, Murata K, Ohno T, Shioyama Y, Tsuji H, Nakano T, Kamada T. Carbon-ion radiotherapy for lymph node oligo-recurrence: a multi-institutional study by the Japan Carbon-Ion Radiation Oncology Study Group (J-CROS). Int J Clin Oncol. 2019 Sep; 24(9):1143-1150. PMID: 30968270.
    Citations: 1     Fields:    Translation:HumansCTClinical Trials
  21. Murata H, Okonogi N, Wakatsuki M, Kato S, Kiyohara H, Karasawa K, Ohno T, Nakano T, Kamada T, Shozu M, The Working Group Of Gynecological Tumors TWGOG. Long-Term Outcomes of Carbon-Ion Radiotherapy for Malignant Gynecological Melanoma. Cancers (Basel). 2019 Apr 04; 11(4). PMID: 30987391.
    Citations: 4     
  22. Kubota Y, Ohno T, Kawashima M, Murata K, Okonogi N, Noda SE, Tsuda K, Sakai M, Tashiro M, Nakano T. Development of a Vaginal Immobilization Device: A Treatment-planning Study of Carbon-ion Radiotherapy and Intensity-modulated Radiation Therapy for Uterine Cervical Cancer. Anticancer Res. 2019 Apr; 39(4):1915-1921. PMID: 30952733.
    Citations: 3     Fields:    Translation:HumansPHPublic Health
  23. Okonogi N, Wakatsuki M, Kato S, Karasawa K, Miyasaka Y, Murata H, Nakano T, Kamada T, Shozu M. A Phase 1/2 Study of Carbon Ion Radiation Therapy With Concurrent Chemotherapy for Locally Advanced Uterine Cervical Squamous Cell Carcinoma (Protocol 1302). Int J Radiat Oncol Biol Phys. 2019 07 01; 104(3):631-639. PMID: 30825494.
    Citations: 1     Fields:    Translation:HumansCTClinical Trials
  24. Murata H, Okamoto M, Takahashi T, Motegi M, Ogoshi K, Shoji H, Onishi M, Takakusagi Y, Okonogi N, Kawamura H, Okazaki A, Asao T, Kuwano H, Nakano T. SUVmax-based Parameters of FDG-PET/CT Reliably Predict Pathologic Complete Response After Preoperative Hyperthermo-chemoradiotherapy in Rectal Cancer. Anticancer Res. 2018 Oct; 38(10):5909-5916. PMID: 30275218.
    Citations: 1     Fields:    Translation:Humans
  25. Ohno T, Noda SE, Murata K, Yoshimoto Y, Okonogi N, Ando K, Tamaki T, Kato S, Hirakawa T, Kanuma T, Minegishi T, Nakano T. Phase I Study of Carbon Ion Radiotherapy and Image-Guided Brachytherapy for Locally Advanced Cervical Cancer. Cancers (Basel). 2018 Sep 18; 10(9). PMID: 30231543.
    Citations: 8     
  26. Ando K, Suzuki Y, Kaminuma T, Yoshimoto Y, Oike T, Okonogi N, Sato H, Tamaki T, Noda SE, Mimura K, Nakano T. Tumor-specific CD8-positive T cell-mediated antitumor immunity is implicated in the antitumor effect of local hyperthermia. Int J Hyperthermia. 2018; 35(1):226-231. PMID: 30221574.
    Citations: 1     Fields:    Translation:HumansAnimalsCells
  27. Onishi M, Okonogi N, Oike T, Yoshimoto Y, Sato H, Suzuki Y, Kamada T, Nakano T. High linear energy transfer carbon-ion irradiation increases the release of the immune mediator high mobility group box 1 from human cancer cells. J Radiat Res. 2018 Sep 01; 59(5):541-546. PMID: 29947767.
    Citations: 11     Fields:    Translation:HumansCells
  28. Nuryadi E, Sasaki Y, Hagiwara Y, Permata TBM, Sato H, Komatsu S, Yoshimoto Y, Murata K, Ando K, Kubo N, Okonogi N, Takakusagi Y, Adachi A, Iwanaga M, Tsuchida K, Tamaki T, Noda SE, Hirota Y, Shibata A, Ohno T, Tokino T, Oike T, Nakano T. Mutational analysis of uterine cervical cancer that survived multiple rounds of radiotherapy. Oncotarget. 2018 Aug 24; 9(66):32642-32652. PMID: 30220971.
    Citations: 3     Fields:    
  29. Okonogi N, Fukahori M, Wakatsuki M, Ohkubo Y, Kato S, Miyasaka Y, Tsuji H, Nakano T, Kamada T. Dose constraints in the rectum and bladder following carbon-ion radiotherapy for uterus carcinoma: a retrospective pooled analysis. Radiat Oncol. 2018 Jun 25; 13(1):119. PMID: 29941040.
    Citations: 3     Fields:    Translation:HumansPHPublic Health
  30. Okonogi N, Suzuki Y, Sato H, Oike T, Yoshimoto Y, Mimura K, Noda SE, Okamoto M, Tamaki T, Morokoshi Y, Hasegawa S, Ohgaki H, Yokoo H, Nakano T. Combination Therapy of Intravenously Injected Microglia and Radiation Therapy Prolongs Survival in a Rat Model of Spontaneous Malignant Glioma. Int J Radiat Oncol Biol Phys. 2018 11 01; 102(3):601-608. PMID: 29928947.
    Citations: 1     Fields:    Translation:HumansAnimalsCells
  31. Irie D, Okonogi N, Wakatsuki M, Kato S, Ohno T, Karasawa K, Kiyohara H, Kobayashi D, Tsuji H, Nakano T, Kamada T, Shozu M. Carbon-ion radiotherapy for inoperable endometrial carcinoma. J Radiat Res. 2018 May 01; 59(3):309-315. PMID: 29528414.
    Citations: 5     Fields:    Translation:Humans
  32. Okonogi N, Wakatsuki M, Kato S, Karasawa K, Kiyohara H, Shiba S, Kobayashi D, Nakano T, Kamada T, Shozu M. Clinical outcomes of carbon ion radiotherapy with concurrent chemotherapy for locally advanced uterine cervical adenocarcinoma in a phase 1/2 clinical trial (Protocol 1001). Cancer Med. 2018 02; 7(2):351-359. PMID: 29341491.
    Citations: 7     Fields:    Translation:HumansCTClinical Trials
  33. Okonogi N, Wakatsuki M, Kato S, Shiba S, Kobayashi D, Kiyohara H, Karasawa K, Ohno T, Nakano T, Kamada T, Shozu M. Long-term Outcomes of Carbon-ion Radiotherapy for Locally Advanced Squamous Cell Carcinoma of the Uterine Cervix. Anticancer Res. 2018 01; 38(1):457-463. PMID: 29277809.
    Citations: 1     Fields:    Translation:HumansCTClinical Trials
  34. Okonogi N, Kobayashi D, Suga T, Imai T, Wakatsuki M, Ohno T, Kato S, Nakano T, Kamada T. Human papillomavirus genotype affects metastatic rate following radiotherapy in patients with uterine cervical cancer. Oncol Lett. 2018 Jan; 15(1):459-466. PMID: 29387229.
    Citations: 8     
  35. Shiba S, Okonogi N, Kato S, Wakatsuki M, Kobayashi D, Kiyohara H, Ohno T, Karasawa K, Nakano T, Kamada T. Clinical Impact of Re-irradiation with Carbon-ion Radiotherapy for Lymph Node Recurrence of Gynecological Cancers. Anticancer Res. 2017 10; 37(10):5577-5583. PMID: 28982873.
    Citations: 2     Fields:    Translation:Humans
  36. Kawashima M, Kawamura H, Onishi M, Takakusagi Y, Okonogi N, Okazaki A, Sekihara T, Ando Y, Nakano T. The Impact of the Grid Size on TomoTherapy for Prostate Cancer. J Med Phys. 2017 Jul-Sep; 42(3):144-150. PMID: 28974860.
  37. Ohno T, Noda SE, Okonogi N, Murata K, Shibuya K, Kiyohara H, Tamaki T, Ando K, Oike T, Ohkubo Y, Wakatsuki M, Saitoh JI, Nakano T. In-room computed tomography-based brachytherapy for uterine cervical cancer: results of a 5-year retrospective study. J Radiat Res. 2017 Jul 01; 58(4):543-551. PMID: 27986859.
    Citations: 17     Fields:    Translation:Humans
  38. Shiba S, Wakatsuki M, Kato S, Ohno T, Okonogi N, Karasawa K, Kiyohara H, Tsujii H, Nakano T, Kamada T, Shozu M. Carbon-ion radiotherapy for locally advanced cervical cancer with bladder invasion. J Radiat Res. 2016 Nov; 57(6):684-690. PMID: 27422932.
    Citations: 4     Fields:    Translation:Humans
  39. Shoji H, Motegi M, Osawa K, Okonogi N, Okazaki A, Andou Y, Asao T, Kuwano H, Takahashi T, Ogoshi K. Radiofrequency thermal treatment with chemoradiotherapy for advanced rectal cancer. Oncol Rep. 2016 May; 35(5):2569-75. PMID: 26985914.
    Citations: 2     Fields:    Translation:Humans
  40. Oike T, Niimi A, Okonogi N, Murata K, Matsumura A, Noda SE, Kobayashi D, Iwanaga M, Tsuchida K, Kanai T, Ohno T, Shibata A, Nakano T. Visualization of complex DNA double-strand breaks in a tumor treated with carbon ion radiotherapy. Sci Rep. 2016 Mar 01; 6:22275. PMID: 26925533.
    Citations: 16     Fields:    Translation:HumansCells
  41. Shoji H, Motegi M, Osawa K, Okonogi N, Okazaki A, Andou Y, Asao T, Kuwano H, Takahashi T, Ogoshi K. Output-limiting symptoms induced by radiofrequency hyperthermia. Are they predictable? Int J Hyperthermia. 2016; 32(2):199-203. PMID: 26644170.
    Citations: 2     Fields:    Translation:HumansCTClinical Trials
  42. Okonogi N, Katoh H, Kawamura H, Tamaki T, Kaminuma T, Murata K, Ohkubo Y, Takakusagi Y, Onishi M, Sekihara T, Okazaki A, Nakano T. Clinical outcomes of helical tomotherapy for super-elderly patients with localized and locally advanced prostate cancer: comparison with patients under 80 years of age. J Radiat Res. 2015 Nov; 56(6):889-96. PMID: 26320208.
    Citations: 3     Fields:    Translation:Humans
  43. Ushijima H, Suzuki Y, Oike T, Komachi M, Yoshimoto Y, Ando K, Okonogi N, Sato H, Noda SE, Saito J, Nakano T. Radio-sensitization effect of an mTOR inhibitor, temsirolimus, on lung adenocarcinoma A549 cells under normoxic and hypoxic conditions. J Radiat Res. 2015 Jul; 56(4):663-8. PMID: 25887043.
    Citations: 9     Fields:    Translation:HumansCells
  44. Yoshimoto Y, Oike T, Okonogi N, Suzuki Y, Ando K, Sato H, Noda SE, Isono M, Mimura K, Kono K, Nakano T. Carbon-ion beams induce production of an immune mediator protein, high mobility group box 1, at levels comparable with X-ray irradiation. J Radiat Res. 2015 May; 56(3):509-14. PMID: 25755254.
    Citations: 17     Fields:    Translation:HumansCells
  45. Okonogi N, Shirai K, Oike T, Murata K, Noda SE, Suzuki Y, Nakano T. Topics in chemotherapy, molecular-targeted therapy, and immunotherapy for newly-diagnosed glioblastoma multiforme. Anticancer Res. 2015 Mar; 35(3):1229-35. PMID: 25750269.
    Citations: 9     Fields:    Translation:HumansAnimals
  46. Shoji H, Motegi M, Osawa K, Okonogi N, Okazaki A, Andou Y, Asao T, Kuwano H, Takahashi T, Ogoshi K. A novel strategy of radiofrequency hyperthermia (neothermia) in combination with preoperative chemoradiotherapy for the treatment of advanced rectal cancer: a pilot study. Cancer Med. 2015 Jun; 4(6):834-43. PMID: 25664976.
    Citations: 6     Fields:    Translation:Humans
  47. Sato H, Suzuki Y, Ide M, Katoh T, Noda SE, Ando K, Oike T, Yoshimoto Y, Okonogi N, Mimura K, Asao T, Kuwano H, Nakano T. HLA class I expression and its alteration by preoperative hyperthermo-chemoradiotherapy in patients with rectal cancer. PLoS One. 2014; 9(9):e108122. PMID: 25259797.
    Citations: 7     Fields:    Translation:Humans
  48. Okonogi N, Nakamura K, Suzuki Y, Suto N, Suzue K, Kaminuma T, Nakano T, Hirai H. Cranial irradiation induces bone marrow-derived microglia in adult mouse brain tissue. J Radiat Res. 2014 Jul; 55(4):713-9. PMID: 24706998.
    Citations: 10     Fields:    Translation:AnimalsCells
  49. Yoshimoto Y, Suzuki Y, Mimura K, Ando K, Oike T, Sato H, Okonogi N, Maruyama T, Izawa S, Noda SE, Fujii H, Kono K, Nakano T. Radiotherapy-induced anti-tumor immunity contributes to the therapeutic efficacy of irradiation and can be augmented by CTLA-4 blockade in a mouse model. PLoS One. 2014; 9(3):e92572. PMID: 24686897.
    Citations: 36     Fields:    Translation:AnimalsCells
  50. Okonogi N, Saitoh J, Suzuki Y, Noda SE, Ohno T, Oike T, Ohkubo Y, Ando K, Sato H, Nakano T. Changes in bone mineral density in uterine cervical cancer patients after radiation therapy. Int J Radiat Oncol Biol Phys. 2013 Dec 01; 87(5):968-74. PMID: 24139516.
    Citations: 2     Fields:    Translation:Humans
  51. Okonogi N, Ebara T, Ishikawa H, Yoshida D, Ueno M, Maeno T, Suga T, Nakano T. A seven-year disease-free survivor of malignant pleural mesothelioma treated with hyperthermia and chemotherapy: a case report. J Med Case Rep. 2012 Dec 28; 6:427. PMID: 23272646.
    Citations: 2     Fields:    
  52. Okonogi N, Hashimoto T, Ishida M, Ohno T, Terunuma T, Okumura T, Sakae T, Sakurai H. Designed-seamless irradiation technique for extended whole mediastinal proton-beam irradiation for esophageal cancer. Radiat Oncol. 2012 Oct 19; 7:173. PMID: 23078998.
    Citations: 6     Fields:    Translation:HumansCTClinical Trials
  53. Oike T, Ohno T, Wakatsuki M, Noda SE, Saitoh J, Mizukami T, Yoshimoto Y, Okonogi N, Katoh H, Shibuya K, Suzuki Y, Ishikawa H, Ebara T, Takahashi T, Nakano T. The benefit of small bowel and pelvic bone sparing in excluding common iliac lymph node region from conventional radiation fields in patients with uterine cervical cancer: a dosimetric study. J Radiat Res. 2010; 51(6):715-21. PMID: 20972366.
    Citations: 3     Fields:    Translation:HumansPHPublic Health
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.