Harvard Catalyst Profiles

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Layal Chaker, Ph.D.

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Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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  1. Wright K, Chaker L, Pacione D, Sam K, Feelders R, Xia Y, Agrawal N. Determinants of Surgical Remission in Prolactinomas: A Systematic Review and Meta-Analysis. World Neurosurg. 2021 Jul 26. PMID: 34325023.
    Citations:    Fields:    
  2. Kus A, Kjaergaard AD, Marouli E, Del Greco M F, Sterenborg RBTM, Chaker L, Peeters RP, Bednarczuk T, Åsvold BO, Burgess S, Deloukas P, Teumer A, Ellervik C, Medici M. Thyroid Function and Mood Disorders: A Mendelian Randomization Study. Thyroid. 2021 08; 31(8):1171-1181. PMID: 33899528.
    Citations:    Fields:    
  3. van der Burgh AC, Hoorn EJ, Chaker L. Removing Race From Kidney Function Estimates. JAMA. 2021 05 18; 325(19):2018. PMID: 34003230.
    Citations:    Fields:    
  4. Khan SR, van der Burgh AC, Peeters RP, van Hagen PM, Dalm VASH, Chaker L. Determinants of Serum Immunoglobulin Levels: A Systematic Review and Meta-Analysis. Front Immunol. 2021; 12:664526. PMID: 33897714.
    Citations:    Fields:    
  5. Roa Dueñas OH, Koolhaas C, Voortman T, Franco OH, Ikram MA, Peeters RP, Chaker L. Thyroid Function and Physical Activity: A Population-Based Cohort Study. Thyroid. 2021 06; 31(6):870-875. PMID: 33198599.
    Citations: 1     Fields:    
  6. Gorski M, Jung B, Li Y, Matias-Garcia PR, Wuttke M, Coassin S, Thio CHL, Kleber ME, Winkler TW, Wanner V, Chai JF, Chu AY, Cocca M, Feitosa MF, Ghasemi S, Hoppmann A, Horn K, Li M, Nutile T, Scholz M, Sieber KB, Teumer A, Tin A, Wang J, Tayo BO, Ahluwalia TS, Almgren P, Bakker SJL, Banas B, Bansal N, Biggs ML, Boerwinkle E, Bottinger EP, Brenner H, Carroll RJ, Chalmers J, Chee ML, Chee ML, Cheng CY, Coresh J, de Borst MH, Degenhardt F, Eckardt KU, Endlich K, Franke A, Freitag-Wolf S, Gampawar P, Gansevoort RT, Ghanbari M, Gieger C, Hamet P, Ho K, Hofer E, Holleczek B, Xian Foo VH, Hutri-Kähönen N, Hwang SJ, Ikram MA, Josyula NS, Kähönen M, Khor CC, Koenig W, Kramer H, Krämer BK, Kühnel B, Lange LA, Lehtimäki T, Lieb W, Loos RJF, Lukas MA, Lyytikäinen LP, Meisinger C, Meitinger T, Melander O, Milaneschi Y, Mishra PP, Mononen N, Mychaleckyj JC, Nadkarni GN, Nauck M, Nikus K, Ning B, Nolte IM, O'Donoghue ML, Orho-Melander M, Pendergrass SA, Penninx BWJH, Preuss MH, Psaty BM, Raffield LM, Raitakari OT, Rettig R, Rheinberger M, Rice KM, Rosenkranz AR, Rossing P, Rotter JI, Sabanayagam C, Schmidt H, Schmidt R, Schöttker B, Schulz CA, Sedaghat S, Shaffer CM, Strauch K, Szymczak S, Taylor KD, Tremblay J, Chaker L, van der Harst P, van der Most PJ, Verweij N, Völker U, Waldenberger M, Wallentin L, Waterworth DM, White HD, Wilson JG, Wong TY, Woodward M, Yang Q, Yasuda M, Yerges-Armstrong LM, Zhang Y, Snieder H, Wanner C, Böger CA, Köttgen A, Kronenberg F, Pattaro C, Heid IM. Meta-analysis uncovers genome-wide significant variants for rapid kidney function decline. Kidney Int. 2021 04; 99(4):926-939. PMID: 33137338.
    Citations: 2     Fields:    Translation:Humans
  7. Kus A, Marouli E, Del Greco M F, Chaker L, Bednarczuk T, Peeters RP, Teumer A, Medici M, Deloukas P. Variation in Normal Range Thyroid Function Affects Serum Cholesterol Levels, Blood Pressure, and Type 2 Diabetes Risk: A Mendelian Randomization Study. Thyroid. 2021 05; 31(5):721-731. PMID: 32746749.
    Citations: 1     Fields:    
  8. Zhou W, Brumpton B, Kabil O, Gudmundsson J, Thorleifsson G, Weinstock J, Zawistowski M, Nielsen JB, Chaker L, Medici M, Teumer A, Naitza S, Sanna S, Schultheiss UT, Cappola A, Karjalainen J, Kurki M, Oneka M, Taylor P, Fritsche LG, Graham SE, Wolford BN, Overton W, Rasheed H, Haug EB, Gabrielsen ME, Skogholt AH, Surakka I, Davey Smith G, Pandit A, Roychowdhury T, Hornsby WE, Jonasson JG, Senter L, Liyanarachchi S, Ringel MD, Xu L, Kiemeney LA, He H, Netea-Maier RT, Mayordomo JI, Plantinga TS, Hrafnkelsson J, Hjartarson H, Sturgis EM, Palotie A, Daly M, Citterio CE, Arvan P, Brummett CM, Boehnke M, de la Chapelle A, Stefansson K, Hveem K, Willer CJ, Åsvold BO. GWAS of thyroid stimulating hormone highlights pleiotropic effects and inverse association with thyroid cancer. Nat Commun. 2020 08 07; 11(1):3981. PMID: 32769997.
    Citations: 2     Fields:    Translation:Humans
  9. Marouli E, Kus A, Del Greco M F, Chaker L, Peeters R, Teumer A, Deloukas P, Medici M. Thyroid Function Affects the Risk of Stroke via Atrial Fibrillation: A Mendelian Randomization Study. J Clin Endocrinol Metab. 2020 08 01; 105(8). PMID: 32374820.
    Citations: 3     Fields:    Translation:Humans
  10. Derakhshan A, Peeters RP, Taylor PN, Bliddal S, Carty DM, Meems M, Vaidya B, Chen L, Knight BA, Ghafoor F, Popova PV, Mosso L, Oken E, Suvanto E, Hisada A, Yoshinaga J, Brown SJ, Bassols J, Auvinen J, Bramer WM, López-Bermejo A, Dayan CM, French R, Boucai L, Vafeiadi M, Grineva EN, Pop VJM, Vrijkotte TG, Chatzi L, Sunyer J, Jiménez-Zabala A, Riaño I, Rebagliato M, Lu X, Pirzada A, Männistö T, Delles C, Feldt-Rasmussen U, Alexander EK, Nelson SM, Chaker L, Pearce EN, Guxens M, Steegers EAP, Walsh JP, Korevaar TIM. Association of maternal thyroid function with birthweight: a systematic review and individual-participant data meta-analysis. Lancet Diabetes Endocrinol. 2020 06; 8(6):501-510. PMID: 32445737.
    Citations: 10     Fields:    Translation:Humans
  11. Kus A, Chaker L, Teumer A, Peeters RP, Medici M. The Genetic Basis of Thyroid Function: Novel Findings and New Approaches. J Clin Endocrinol Metab. 2020 06 01; 105(6). PMID: 32271924.
    Citations: 6     Fields:    Translation:Humans
  12. Bano A, Chaker L, Muka T, Mattace-Raso FUS, Bally L, Franco OH, Peeters RP, Razvi S. Thyroid Function and the Risk of Fibrosis of the Liver, Heart, and Lung in Humans: A Systematic Review and Meta-Analysis. Thyroid. 2020 06; 30(6):806-820. PMID: 31910097.
    Citations: 5     Fields:    Translation:Humans
  13. Nelson RG, Grams ME, Ballew SH, Sang Y, Azizi F, Chadban SJ, Chaker L, Dunning SC, Fox C, Hirakawa Y, Iseki K, Ix J, Jafar TH, Köttgen A, Naimark DMJ, Ohkubo T, Prescott GJ, Rebholz CM, Sabanayagam C, Sairenchi T, Schöttker B, Shibagaki Y, Tonelli M, Zhang L, Gansevoort RT, Matsushita K, Woodward M, Coresh J, Shalev V. Development of Risk Prediction Equations for Incident Chronic Kidney Disease. JAMA. 2019 12 03; 322(21):2104-2114. PMID: 31703124.
    Citations: 9     Fields:    Translation:Humans
  14. Bano A, Chaker L, Mattace-Raso FUS, Terzikhan N, Kavousi M, Ikram MA, Peeters RP, Franco OH. Thyroid function and life expectancy with and without noncommunicable diseases: A population-based study. PLoS Med. 2019 10; 16(10):e1002957. PMID: 31652264.
    Citations: 2     Fields:    Translation:Humans
  15. Korevaar TIM, Derakhshan A, Taylor PN, Meima M, Chen L, Bliddal S, Carty DM, Meems M, Vaidya B, Shields B, Ghafoor F, Popova PV, Mosso L, Oken E, Suvanto E, Hisada A, Yoshinaga J, Brown SJ, Bassols J, Auvinen J, Bramer WM, López-Bermejo A, Dayan C, Boucai L, Vafeiadi M, Grineva EN, Tkachuck AS, Pop VJM, Vrijkotte TG, Guxens M, Chatzi L, Sunyer J, Jiménez-Zabala A, Riaño I, Murcia M, Lu X, Mukhtar S, Delles C, Feldt-Rasmussen U, Nelson SM, Alexander EK, Chaker L, Männistö T, Walsh JP, Pearce EN, Steegers EAP, Peeters RP. Association of Thyroid Function Test Abnormalities and Thyroid Autoimmunity With Preterm Birth: A Systematic Review and Meta-analysis. JAMA. 2019 08 20; 322(7):632-641. PMID: 31429897.
    Citations: 32     Fields:    Translation:Humans
  16. Bano A, Chaker L, de Maat MPM, Atiq F, Kavousi M, Franco OH, Mattace-Raso FUS, Leebeek FWG, Peeters RP. Thyroid Function and Cardiovascular Disease: The Mediating Role of Coagulation Factors. J Clin Endocrinol Metab. 2019 08 01; 104(8):3203-3212. PMID: 30938758.
    Citations: 4     Fields:    Translation:Humans
  17. Teumer A, Chaker L, Groeneweg S, Li Y, Di Munno C, Barbieri C, Schultheiss UT, Traglia M, Ahluwalia TS, Akiyama M, Appel EVR, Arking DE, Arnold A, Astrup A, Beekman M, Beilby JP, Bekaert S, Boerwinkle E, Brown SJ, De Buyzere M, Campbell PJ, Ceresini G, Cerqueira C, Cucca F, Deary IJ, Deelen J, Eckardt KU, Ekici AB, Eriksson JG, Ferrrucci L, Fiers T, Fiorillo E, Ford I, Fox CS, Fuchsberger C, Galesloot TE, Gieger C, Gögele M, De Grandi A, Grarup N, Greiser KH, Haljas K, Hansen T, Harris SE, van Heemst D, den Heijer M, Hicks AA, den Hollander W, Homuth G, Hui J, Ikram MA, Ittermann T, Jensen RA, Jing J, Jukema JW, Kajantie E, Kamatani Y, Kasbohm E, Kaufman JM, Kiemeney LA, Kloppenburg M, Kronenberg F, Kubo M, Lahti J, Lapauw B, Li S, Liewald DCM, Lim EM, Linneberg A, Marina M, Mascalzoni D, Matsuda K, Medenwald D, Meisinger C, Meulenbelt I, De Meyer T, Meyer Zu Schwabedissen HE, Mikolajczyk R, Moed M, Netea-Maier RT, Nolte IM, Okada Y, Pala M, Pattaro C, Pedersen O, Petersmann A, Porcu E, Postmus I, Pramstaller PP, Psaty BM, Ramos YFM, Rawal R, Redmond P, Richards JB, Rietzschel ER, Rivadeneira F, Roef G, Rotter JI, Sala CF, Schlessinger D, Selvin E, Slagboom PE, Soranzo N, Sørensen TIA, Spector TD, Starr JM, Stott DJ, Taes Y, Taliun D, Tanaka T, Thuesen B, Tiller D, Toniolo D, Uitterlinden AG, Visser WE, Walsh JP, Wilson SG, Wolffenbuttel BHR, Yang Q, Zheng HF, Cappola A, Peeters RP, Naitza S, Völzke H, Sanna S, Köttgen A, Visser TJ, Medici M. Genome-wide analyses identify a role for SLC17A4 and AADAT in thyroid hormone regulation. Nat Commun. 2018 10 26; 9(1):4455. PMID: 30367059.
    Citations: 24     Fields:    Translation:HumansAnimalsCells
  18. Chaker L, Cappola AR, Mooijaart SP, Peeters RP. Clinical aspects of thyroid function during ageing. Lancet Diabetes Endocrinol. 2018 09; 6(9):733-742. PMID: 30017801.
    Citations: 12     Fields:    Translation:Humans
  19. McAninch EA, Rajan KB, Evans DA, Jo S, Chaker L, Peeters RP, Bennett DA, Mash DC, Bianco AC. A Common DIO2 Polymorphism and Alzheimer Disease Dementia in African and European Americans. J Clin Endocrinol Metab. 2018 05 01; 103(5):1818-1826. PMID: 29481662.
    Citations: 9     Fields:    Translation:Humans
  20. Massolt ET, Chaker L, Visser TJ, Gillis AJM, Dorssers LCJ, Beukhof CM, Kam BLR, Franssen GJ, Brigante G, van Ginhoven TM, Visser WE, Looijenga LHJ, Peeters RP. Serum microRNA profiles in athyroid patients on and off levothyroxine therapy. PLoS One. 2018; 13(4):e0194259. PMID: 29649216.
    Citations: 2     Fields:    Translation:Humans
  21. Bos D, Bano A, Hofman A, VanderWeele TJ, Kavousi M, Franco OH, Vernooij MW, Peeters RP, Ikram MA, Chaker L. Thyroid function and atrial fibrillation: Is there a mediating role for epicardial adipose tissue? Clin Epidemiol. 2018; 10:225-234. PMID: 29535556.
    Citations:    
  22. Korevaar TIM, Pop VJ, Chaker L, Goddijn M, de Rijke YB, Bisschop PH, Broeren MA, Jaddoe VWV, Medici M, Visser TJ, Steegers EAP, Vrijkotte TG, Peeters RP. Dose Dependency and a Functional Cutoff for TPO-Antibody Positivity During Pregnancy. J Clin Endocrinol Metab. 2018 02 01; 103(2):778-789. PMID: 29240902.
    Citations: 11     Fields:    Translation:Humans
  23. Chaker L, Bianco AC, Jonklaas J, Peeters RP. Hypothyroidism and hypertension: fact or myth? - Authors' reply. Lancet. 2018 01 06; 391(10115):30. PMID: 29323655.
    Citations: 2     Fields:    Translation:Humans
  24. Bano A, Chaker L, Schoufour J, Ikram MA, Kavousi M, Franco OH, Peeters RP, Mattace-Raso FUS. High Circulating Free Thyroxine Levels May Increase the Risk of Frailty: The Rotterdam Study. J Clin Endocrinol Metab. 2018 01 01; 103(1):328-335. PMID: 29126162.
    Citations: 6     Fields:    Translation:Humans
  25. Bano A, Dhana K, Chaker L, Kavousi M, Ikram MA, Mattace-Raso FUS, Peeters RP, Franco OH. Association of Thyroid Function With Life Expectancy With and Without Cardiovascular Disease: The Rotterdam Study. JAMA Intern Med. 2017 11 01; 177(11):1650-1657. PMID: 28975207.
    Citations: 12     Fields:    Translation:Humans
  26. Bano A, Chaker L, Mattace-Raso FUS, van der Lugt A, Ikram MA, Franco OH, Peeters RP, Kavousi M. Thyroid Function and the Risk of Atherosclerotic Cardiovascular Morbidity and Mortality: The Rotterdam Study. Circ Res. 2017 Dec 08; 121(12):1392-1400. PMID: 29089349.
    Citations: 16     Fields:    Translation:Humans
  27. Önsesveren I, Barjaktarovic M, Chaker L, de Rijke YB, Jaddoe VWV, van Santen HM, Visser TJ, Peeters RP, Korevaar TIM. Childhood Thyroid Function Reference Ranges and Determinants: A Literature Overview and a Prospective Cohort Study. Thyroid. 2017 11; 27(11):1360-1369. PMID: 28942709.
    Citations: 4     Fields:    Translation:Humans
  28. Korevaar TIM, Chaker L, Peeters RP. Improving the clinical impact of randomised trials in thyroidology. Lancet Diabetes Endocrinol. 2018 07; 6(7):523-525. PMID: 29030202.
    Citations: 5     Fields:    Translation:Humans
  29. Chaker L, Cremers LGM, Korevaar TIM, de Groot M, Dehghan A, Franco OH, Niessen WJ, Ikram MA, Peeters RP, Vernooij MW. Age-dependent association of thyroid function with brain morphology and microstructural organization: evidence from brain imaging. Neurobiol Aging. 2018 01; 61:44-51. PMID: 29032192.
    Citations: 2     Fields:    Translation:Humans
  30. Korevaar TIM, Steegers EAP, Chaker L, Medici M, Jaddoe VWV, Visser TJ, de Rijke YB, Peeters RP. Thyroid Function and Premature Delivery in TPO Antibody-Negative Women: The Added Value of hCG. J Clin Endocrinol Metab. 2017 09 01; 102(9):3360-3367. PMID: 28911134.
    Citations: 4     Fields:    Translation:Humans
  31. Beukhof CM, van Doorn L, Visser TJ, Bins S, Visser WE, van Heerebeek R, van Kemenade FJ, de Rijke YB, de Herder WW, Chaker L, Mathijssen RH, Peeters RP. Sorafenib-Induced Changes in Thyroid Hormone Levels in Patients Treated for Hepatocellular Carcinoma. J Clin Endocrinol Metab. 2017 08 01; 102(8):2922-2929. PMID: 28575418.
    Citations: 2     Fields:    Translation:HumansAnimalsCells
  32. Chaker L, Korevaar TIM, Rizopoulos D, Collet TH, Völzke H, Hofman A, Rodondi N, Cappola AR, Peeters RP, Franco OH. Defining Optimal Health Range for Thyroid Function Based on the Risk of Cardiovascular Disease. J Clin Endocrinol Metab. 2017 08 01; 102(8):2853-2861. PMID: 28520952.
    Citations: 9     Fields:    Translation:Humans
  33. Khan SR, Bano A, Wakkee M, Korevaar TIM, Franco OH, Nijsten TEC, Peeters RP, Chaker L. The association of autoimmune thyroid disease (AITD) with psoriatic disease: a prospective cohort study, systematic review and meta-analysis. Eur J Endocrinol. 2017 Oct; 177(4):347-359. PMID: 28747386.
    Citations: 4     Fields:    Translation:Humans
  34. Medici M, Chaker L, Peeters RP. A Step Forward in Understanding the Relevance of Genetic Variation in Type 2 Deiodinase. J Clin Endocrinol Metab. 2017 05 01; 102(5):1775-1778. PMID: 28482082.
    Citations: 3     Fields:    Translation:Humans
  35. Chaker L, Cappola AR, Rodondi N, Peeters RP. Response to the Letter by Choy. J Clin Endocrinol Metab. 2017 04 01; 102(4):1409-1410. PMID: 28388731.
    Citations:    Fields:    Translation:Humans
  36. Chaker L, Bianco AC, Jonklaas J, Peeters RP. Hypothyroidism. Lancet. 2017 Sep 23; 390(10101):1550-1562. PMID: 28336049.
    Citations: 117     Fields:    
  37. Barjaktarovic M, Korevaar TI, Chaker L, Jaddoe VW, de Rijke YB, Visser TJ, Steegers EA, Peeters RP. The association of maternal thyroid function with placental hemodynamics. Hum Reprod. 2017 03 01; 32(3):653-661. PMID: 28130433.
    Citations: 7     Fields:    Translation:Humans
  38. Chaker L, van den Berg M, Stricker BH, Peeters RP. Response by Chaker et al to Letter Regarding Article, "Thyroid Function and Sudden Cardiac Death: A Prospective Population-Based Cohort Study". Circulation. 2017 02 21; 135(8):e90-e91. PMID: 28223331.
    Citations:    Fields:    Translation:Humans
  39. Korevaar TI, de Rijke YB, Chaker L, Medici M, Jaddoe VW, Steegers EA, Visser TJ, Peeters RP. Stimulation of Thyroid Function by Human Chorionic Gonadotropin During Pregnancy: A Risk Factor for Thyroid Disease and a Mechanism for Known Risk Factors. Thyroid. 2017 03; 27(3):440-450. PMID: 28049387.
    Citations: 7     Fields:    Translation:Humans
  40. Chaker L, Peeters RP. [What is a normal thyroid function?] Ned Tijdschr Geneeskd. 2017; 161:D926. PMID: 28351434.
    Citations:    Fields:    Translation:Humans
  41. Korevaar TI, Steegers EA, Pop VJ, Broeren MA, Chaker L, de Rijke YB, Jaddoe VW, Medici M, Visser TJ, Tiemeier H, Peeters RP. Thyroid Autoimmunity Impairs the Thyroidal Response to Human Chorionic Gonadotropin: Two Population-Based Prospective Cohort Studies. J Clin Endocrinol Metab. 2017 01 01; 102(1):69-77. PMID: 27754809.
    Citations: 16     Fields:    Translation:Humans
  42. Bano A, Chaker L, Darweesh SK, Korevaar TI, Mattace-Raso FU, Dehghan A, Franco OH, van der Geest JN, Ikram MA, Peeters RP. Gait patterns associated with thyroid function: The Rotterdam Study. Sci Rep. 2016 12 14; 6:38912. PMID: 27966590.
    Citations: 2     Fields:    Translation:HumansCTClinical Trials
  43. Chaker L, Sedaghat S, Hoorn EJ, Elzen WP, Gussekloo J, Hofman A, Ikram MA, Franco OH, Dehghan A, Peeters RP. The association of thyroid function and the risk of kidney function decline: a population-based cohort study. Eur J Endocrinol. 2016 Dec; 175(6):653-660. PMID: 27926474.
    Citations: 8     Fields:    Translation:HumansPHPublic Health
  44. Rieben C, Segna D, da Costa BR, Collet TH, Chaker L, Aubert CE, Baumgartner C, Almeida OP, Hogervorst E, Trompet S, Masaki K, Mooijaart SP, Gussekloo J, Peeters RP, Bauer DC, Aujesky D, Rodondi N. Subclinical Thyroid Dysfunction and the Risk of Cognitive Decline: a Meta-Analysis of Prospective Cohort Studies. J Clin Endocrinol Metab. 2016 12; 101(12):4945-4954. PMID: 27689250.
    Citations: 21     Fields:    Translation:Humans
  45. Chaker L, Ligthart S, Korevaar TI, Hofman A, Franco OH, Peeters RP, Dehghan A. Thyroid function and risk of type 2 diabetes: a population-based prospective cohort study. BMC Med. 2016 Sep 30; 14(1):150. PMID: 27686165.
    Citations: 29     Fields:    
  46. Korevaar TI, Steegers EA, Chaker L, Medici M, Jaddoe VW, Visser TJ, de Rijke YB, Peeters RP. The Risk of Preeclampsia According to High Thyroid Function in Pregnancy Differs by hCG Concentration. J Clin Endocrinol Metab. 2016 12; 101(12):5037-5043. PMID: 27648965.
    Citations: 2     Fields:    Translation:Humans
  47. Khan SR, Chaker L, Ruiter R, Aerts JG, Hofman A, Dehghan A, Franco OH, Stricker BH, Peeters RP. Thyroid Function and Cancer Risk: The Rotterdam Study. J Clin Endocrinol Metab. 2016 12; 101(12):5030-5036. PMID: 27648963.
    Citations: 21     Fields:    Translation:Humans
  48. Chaker L, Wolters FJ, Bos D, Korevaar TI, Hofman A, van der Lugt A, Koudstaal PJ, Franco OH, Dehghan A, Vernooij MW, Peeters RP, Ikram MA. Thyroid function and the risk of dementia: The Rotterdam Study. Neurology. 2016 Oct 18; 87(16):1688-1695. PMID: 27638924.
    Citations: 17     Fields:    Translation:Humans
  49. Chaker L, Baumgartner C, den Elzen WP, Collet TH, Ikram MA, Blum MR, Dehghan A, Drechsler C, Luben RN, Portegies ML, Iervasi G, Medici M, Stott DJ, Dullaart RP, Ford I, Bremner A, Newman AB, Wanner C, Sgarbi JA, Dörr M, Longstreth WT, Psaty BM, Ferrucci L, Maciel RM, Westendorp RG, Jukema JW, Ceresini G, Imaizumi M, Hofman A, Bakker SJ, Franklyn JA, Khaw KT, Bauer DC, Walsh JP, Razvi S, Gussekloo J, Völzke H, Franco OH, Cappola AR, Rodondi N, Peeters RP. Thyroid Function Within the Reference Range and the Risk of Stroke: An Individual Participant Data Analysis. J Clin Endocrinol Metab. 2016 11; 101(11):4270-4282. PMID: 27603906.
    Citations: 16     Fields:    Translation:Humans
  50. Chaker L, van den Berg ME, Niemeijer MN, Franco OH, Dehghan A, Hofman A, Rijnbeek PR, Deckers JW, Eijgelsheim M, Stricker BH, Peeters RP. Thyroid Function and Sudden Cardiac Death: A Prospective Population-Based Cohort Study. Circulation. 2016 Sep 06; 134(10):713-22. PMID: 27601558.
    Citations: 17     Fields:    Translation:HumansPHPublic Health
  51. Chaker L, Korevaar TI, Medici M, Uitterlinden AG, Hofman A, Dehghan A, Franco OH, Peeters RP. Thyroid Function Characteristics and Determinants: The Rotterdam Study. Thyroid. 2016 09; 26(9):1195-204. PMID: 27484151.
    Citations: 13     Fields:    Translation:Humans
  52. Korevaar TI, Nieboer D, Bisschop PH, Goddijn M, Medici M, Chaker L, de Rijke YB, Jaddoe VW, Visser TJ, Steyerberg EW, Tiemeier H, Vrijkotte TG, Peeters RP. Risk factors and a clinical prediction model for low maternal thyroid function during early pregnancy: two population-based prospective cohort studies. Clin Endocrinol (Oxf). 2016 Dec; 85(6):902-909. PMID: 27384268.
    Citations: 3     Fields:    Translation:Humans
  53. Amin N, Jovanova O, Adams HH, Dehghan A, Kavousi M, Vernooij MW, Peeters RP, de Vrij FM, van der Lee SJ, van Rooij JG, van Leeuwen EM, Chaker L, Demirkan A, Hofman A, Brouwer RW, Kraaij R, Willems van Dijk K, Hankemeier T, van Ijcken WF, Uitterlinden AG, Niessen WJ, Franco OH, Kushner SA, Ikram MA, Tiemeier H, van Duijn CM. Exome-sequencing in a large population-based study reveals a rare Asn396Ser variant in the LIPG gene associated with depressive symptoms. Mol Psychiatry. 2017 04; 22(4):634. PMID: 27502476.
    Citations: 3     Fields:    
  54. Amin N, Jovanova O, Adams HH, Dehghan A, Kavousi M, Vernooij MW, Peeters RP, de Vrij FM, van der Lee SJ, van Rooij JG, van Leeuwen EM, Chaker L, Demirkan A, Hofman A, Brouwer RW, Kraaij R, Willems van Dijk K, Hankemeier T, van Ijcken WF, Uitterlinden AG, Niessen WJ, Franco OH, Kushner SA, Ikram MA, Tiemeier H, van Duijn CM. Exome-sequencing in a large population-based study reveals a rare Asn396Ser variant in the LIPG gene associated with depressive symptoms. Mol Psychiatry. 2017 04; 22(4):537-543. PMID: 27431295.
    Citations: 15     Fields:    Translation:Humans
  55. Korevaar TI, Chaker L, Medici M, de Rijke YB, Jaddoe VW, Steegers EA, Tiemeier H, Visser TJ, Peeters RP. Maternal total T4 during the first half of pregnancy: physiologic aspects and the risk of adverse outcomes in comparison with free T4. Clin Endocrinol (Oxf). 2016 Nov; 85(5):757-763. PMID: 27187054.
    Citations: 8     Fields:    Translation:Humans
  56. Bano A, Chaker L, Plompen EP, Hofman A, Dehghan A, Franco OH, Janssen HL, Darwish Murad S, Peeters RP. Thyroid Function and the Risk of Nonalcoholic Fatty Liver Disease: The Rotterdam Study. J Clin Endocrinol Metab. 2016 08; 101(8):3204-11. PMID: 27270473.
    Citations: 30     Fields:    Translation:Humans
  57. Chaker L, Visser TJ. Thyroid function: Thyroid dysfunction and breast cancer risk - an unfinished story. Nat Rev Endocrinol. 2016 06; 12(6):313-4. PMID: 27020258.
    Citations: 3     Fields:    Translation:Humans
  58. Korevaar TI, Chaker L, Jaddoe VW, Visser TJ, Medici M, Peeters RP. Maternal and Birth Characteristics Are Determinants of Offspring Thyroid Function. J Clin Endocrinol Metab. 2016 Jan; 101(1):206-13. PMID: 26583586.
    Citations: 14     Fields:    Translation:Humans
  59. Korevaar TI, Muetzel R, Medici M, Chaker L, Jaddoe VW, de Rijke YB, Steegers EA, Visser TJ, White T, Tiemeier H, Peeters RP. Association of maternal thyroid function during early pregnancy with offspring IQ and brain morphology in childhood: a population-based prospective cohort study. Lancet Diabetes Endocrinol. 2016 Jan; 4(1):35-43. PMID: 26497402.
    Citations: 74     Fields:    Translation:Humans
  60. Chaker L, Heeringa J, Dehghan A, Medici M, Visser WE, Baumgartner C, Hofman A, Rodondi N, Peeters RP, Franco OH. Normal Thyroid Function and the Risk of Atrial Fibrillation: the Rotterdam Study. J Clin Endocrinol Metab. 2015 Oct; 100(10):3718-24. PMID: 26262438.
    Citations: 30     Fields:    Translation:Humans
  61. Chaker L, Buitendijk GH, Dehghan A, Medici M, Hofman A, Vingerling JR, Franco OH, Klaver CC, Peeters RP. Thyroid function and age-related macular degeneration: a prospective population-based cohort study--the Rotterdam Study. BMC Med. 2015 Apr 23; 13:94. PMID: 25903050.
    Citations: 12     Fields:    Translation:Humans
  62. Chaker L, Baumgartner C, den Elzen WP, Ikram MA, Blum MR, Collet TH, Bakker SJ, Dehghan A, Drechsler C, Luben RN, Hofman A, Portegies ML, Medici M, Iervasi G, Stott DJ, Ford I, Bremner A, Wanner C, Ferrucci L, Newman AB, Dullaart RP, Sgarbi JA, Ceresini G, Maciel RM, Westendorp RG, Jukema JW, Imaizumi M, Franklyn JA, Bauer DC, Walsh JP, Razvi S, Khaw KT, Cappola AR, Völzke H, Franco OH, Gussekloo J, Rodondi N, Peeters RP. Subclinical Hypothyroidism and the Risk of Stroke Events and Fatal Stroke: An Individual Participant Data Analysis. J Clin Endocrinol Metab. 2015 Jun; 100(6):2181-91. PMID: 25856213.
    Citations: 37     Fields:    Translation:Humans
  63. Chaker L, Falla A, van der Lee SJ, Muka T, Imo D, Jaspers L, Colpani V, Mendis S, Chowdhury R, Bramer WM, Pazoki R, Franco OH. The global impact of non-communicable diseases on macro-economic productivity: a systematic review. Eur J Epidemiol. 2015 May; 30(5):357-95. PMID: 25837965.
    Citations: 35     Fields:    Translation:Humans
  64. Schultheiss UT, Teumer A, Medici M, Li Y, Daya N, Chaker L, Homuth G, Uitterlinden AG, Nauck M, Hofman A, Selvin E, Völzke H, Peeters RP, Köttgen A. A genetic risk score for thyroid peroxidase antibodies associates with clinical thyroid disease in community-based populations. J Clin Endocrinol Metab. 2015 May; 100(5):E799-807. PMID: 25719932.
    Citations: 13     Fields:    Translation:Humans
  65. Muka T, Imo D, Jaspers L, Colpani V, Chaker L, van der Lee SJ, Mendis S, Chowdhury R, Bramer WM, Falla A, Pazoki R, Franco OH. The global impact of non-communicable diseases on healthcare spending and national income: a systematic review. Eur J Epidemiol. 2015 Apr; 30(4):251-77. PMID: 25595318.
    Citations: 70     Fields:    Translation:Humans
  66. Jaspers L, Colpani V, Chaker L, van der Lee SJ, Muka T, Imo D, Mendis S, Chowdhury R, Bramer WM, Falla A, Pazoki R, Franco OH. The global impact of non-communicable diseases on households and impoverishment: a systematic review. Eur J Epidemiol. 2015 Mar; 30(3):163-88. PMID: 25527371.
    Citations: 42     Fields:    Translation:Humans
  67. Chaker L, Baumgartner C, Ikram MA, Dehghan A, Medici M, Visser WE, Hofman A, Rodondi N, Peeters RP, Franco OH. Subclinical thyroid dysfunction and the risk of stroke: a systematic review and meta-analysis. Eur J Epidemiol. 2014 Nov; 29(11):791-800. PMID: 25179793.
    Citations: 9     Fields:    Translation:Humans
  68. Medici M, Porcu E, Pistis G, Teumer A, Brown SJ, Jensen RA, Rawal R, Roef GL, Plantinga TS, Vermeulen SH, Lahti J, Simmonds MJ, Husemoen LL, Freathy RM, Shields BM, Pietzner D, Nagy R, Broer L, Chaker L, Korevaar TI, Plia MG, Sala C, Völker U, Richards JB, Sweep FC, Gieger C, Corre T, Kajantie E, Thuesen B, Taes YE, Visser WE, Hattersley AT, Kratzsch J, Hamilton A, Li W, Homuth G, Lobina M, Mariotti S, Soranzo N, Cocca M, Nauck M, Spielhagen C, Ross A, Arnold A, van de Bunt M, Liyanarachchi S, Heier M, Grabe HJ, Masciullo C, Galesloot TE, Lim EM, Reischl E, Leedman PJ, Lai S, Delitala A, Bremner AP, Philips DI, Beilby JP, Mulas A, Vocale M, Abecasis G, Forsen T, James A, Widen E, Hui J, Prokisch H, Rietzschel EE, Palotie A, Feddema P, Fletcher SJ, Schramm K, Rotter JI, Kluttig A, Radke D, Traglia M, Surdulescu GL, He H, Franklyn JA, Tiller D, Vaidya B, de Meyer T, Jørgensen T, Eriksson JG, O'Leary PC, Wichmann E, Hermus AR, Psaty BM, Ittermann T, Hofman A, Bosi E, Schlessinger D, Wallaschofski H, Pirastu N, Aulchenko YS, de la Chapelle A, Netea-Maier RT, Gough SC, Meyer Zu Schwabedissen H, Frayling TM, Kaufman JM, Linneberg A, Räikkönen K, Smit JW, Kiemeney LA, Rivadeneira F, Uitterlinden AG, Walsh JP, Meisinger C, den Heijer M, Visser TJ, Spector TD, Wilson SG, Völzke H, Cappola A, Toniolo D, Sanna S, Naitza S, Peeters RP. Identification of novel genetic Loci associated with thyroid peroxidase antibodies and clinical thyroid disease. PLoS Genet. 2014 Feb; 10(2):e1004123. PMID: 24586183.
    Citations: 47     Fields:    Translation:Humans
  69. Chaker L, Segeren CM, Bot FJ, Maartense E. Haemophagocytic syndrome and Hodgkin's disease variant of Richter's syndrome after fludarabine for CLL. Eur J Haematol. 2010 Jul; 85(1):91-2. PMID: 20331737.
    Citations: 4     Fields:    Translation:Humans
  70. Loudon SE, Passchier J, Chaker L, de Vos S, Fronius M, Harrad RA, Looman CW, Simonsz B, Simonsz HJ. Psychological causes of non-compliance with electronically monitored occlusion therapy for amblyopia. Br J Ophthalmol. 2009 Nov; 93(11):1499-503. PMID: 19661070.
    Citations: 11     Fields:    Translation:Humans
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.