Harvard Catalyst Profiles

Contact, publication, and social network information about Harvard faculty and fellows.

Layal Chaker, Ph.D.

Title
Institution
Department
Address

Biography
Erasmus University Medical Center, RotterdamMD
Erasmus University Medical Center, RotterdamPhD2017Epidemiology, Endocrinology

Bibliographic
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
Newest   |   Oldest   |   Most Cited   |   Most Discussed   |   Timeline   |   Field Summary   |   Plain Text
PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Basak EA, de Joode K, Uyl TJJ, van der Wal R, Schreurs MWJ, van den Berg SAA, Oomen-de Hoop E, van der Leest CH, Chaker L, Feelders RA, van der Veldt AAM, Joosse A, Koolen SLW, Aerts JGJV, Mathijssen RHJ, Bins S. The course of C-peptide levels in patients developing diabetes during anti-PD-1 therapy. Biomed Pharmacother. 2022 Dec; 156:113839. PMID: 36228374.
    Citations:    Fields:    
  2. Osinga JAJ, Derakhshan A, Palomaki GE, Ashoor G, Männistö T, Maraka S, Chen L, Bliddal S, Lu X, Taylor PN, Vrijkotte TGM, Tao FB, Brown SJ, Ghafoor F, Poppe K, Veltri F, Chatzi L, Vaidya B, Broeren MAC, Shields BM, Itoh S, Mosso L, Popova PV, Anopova AD, Kishi R, Aminorroaya A, Kianpour M, López-Bermejo A, Oken E, Pirzada A, Vafeiadi M, Bramer WM, Suvanto E, Yoshinaga J, Huang K, Bassols J, Boucai L, Feldt-Rasmussen U, Grineva EN, Pearce EN, Alexander EK, Pop VJM, Nelson SM, Walsh JP, Peeters RP, Chaker L, Nicolaides KH, D'Alton ME, Korevaar TIM. TSH and FT4 Reference Intervals in Pregnancy: A Systematic Review and Individual Participant Data Meta-Analysis. J Clin Endocrinol Metab. 2022 09 28; 107(10):2925-2933. PMID: 35861700; PMCID: PMC9516198.
    Citations:    Fields:    
  3. Khan SR, Yaqub A, Ikram MK, van Hagen PM, Peeters RP, Dalm VASH, Chaker L, Ikram MA. The association of serum immunoglobulins with cognition and dementia: the Rotterdam Study. J Neurol. 2022 Sep 19. PMID: 36123443.
    Citations:    Fields:    
  4. Bliddal S, Derakhshan A, Xiao Y, Chen LM, Männistö T, Ashoor G, Tao F, Brown SJ, Vafeiadi M, Itoh S, Grineva EN, Taylor P, Ghafoor F, Vaidya B, Hattersley A, Mosso L, Oken E, Kishi R, Alexander EK, Maraka S, Huang K, Chaker L, Bassols J, Pirzada A, López-Bermejo A, Boucai L, Peeters RP, Pearce EN, Nelson SM, Chatzi L, Vrijkotte TG, Popova PV, Walsh JP, Nicolaides KH, Suvanto E, Lu X, Pop VJM, Forman JL, Korevaar TIM, Feldt-Rasmussen U. Association of Thyroid Peroxidase Antibodies and Thyroglobulin Antibodies with Thyroid Function in Pregnancy: An Individual Participant Data Meta-Analysis. Thyroid. 2022 07; 32(7):828-840. PMID: 35596568.
    Citations: 1     Fields:    Translation:Humans
  5. Gorski M, Rasheed H, Teumer A, Thomas LF, Graham SE, Sveinbjornsson G, Winkler TW, Günther F, Stark KJ, Chai JF, Tayo BO, Wuttke M, Li Y, Tin A, Ahluwalia TS, Ärnlöv J, Åsvold BO, Bakker SJL, Banas B, Bansal N, Biggs ML, Biino G, Böhnke M, Boerwinkle E, Bottinger EP, Brenner H, Brumpton B, Carroll RJ, Chaker L, Chalmers J, Chee ML, Chee ML, Cheng CY, Chu AY, Ciullo M, Cocca M, Cook JP, Coresh J, Cusi D, de Borst MH, Degenhardt F, Eckardt KU, Endlich K, Evans MK, Feitosa MF, Franke A, Freitag-Wolf S, Fuchsberger C, Gampawar P, Gansevoort RT, Ghanbari M, Ghasemi S, Giedraitis V, Gieger C, Gudbjartsson DF, Hallan S, Hamet P, Hishida A, Ho K, Hofer E, Holleczek B, Holm H, Hoppmann A, Horn K, Hutri-Kähönen N, Hveem K, Hwang SJ, Ikram MA, Josyula NS, Jung B, Kähönen M, Karabegovic I, Khor CC, Koenig W, Kramer H, Krämer BK, Kühnel B, Kuusisto J, Laakso M, Lange LA, Lehtimäki T, Li M, Lieb W, Lind L, Lindgren CM, Loos RJF, Lukas MA, Lyytikäinen LP, Mahajan A, Matias-Garcia PR, Meisinger C, Meitinger T, Melander O, Milaneschi Y, Mishra PP, Mononen N, Morris AP, Mychaleckyj JC, Nadkarni GN, Naito M, Nakatochi M, Nalls MA, Nauck M, Nikus K, Ning B, Nolte IM, Nutile T, O'Donoghue ML, O'Connell J, Olafsson I, Orho-Melander M, Parsa A, Pendergrass SA, Penninx BWJH, Pirastu M, Preuss MH, Psaty BM, Raffield LM, Raitakari OT, Rheinberger M, Rice KM, Rizzi F, Rosenkranz AR, Rossing P, Rotter JI, Ruggiero D, Ryan KA, Sabanayagam C, Salvi E, Schmidt H, Schmidt R, Scholz M, Schöttker B, Schulz CA, Sedaghat S, Shaffer CM, Sieber KB, Sim X, Sims M, Snieder H, Stanzick KJ, Thorsteinsdottir U, Stocker H, Strauch K, Stringham HM, Sulem P, Szymczak S, Taylor KD, Thio CHL, Tremblay J, Vaccargiu S, van der Harst P, van der Most PJ, Verweij N, Völker U, Wakai K, Waldenberger M, Wallentin L, Wallner S, Wang J, Waterworth DM, White HD, Willer CJ, Wong TY, Woodward M, Yang Q, Yerges-Armstrong LM, Zimmermann M, Zonderman AB, Bergler T, Stefansson K, Böger CA, Pattaro C, Köttgen A, Kronenberg F, Heid IM. Genetic loci and prioritization of genes for kidney function decline derived from a meta-analysis of 62 longitudinal genome-wide association studies. Kidney Int. 2022 09; 102(3):624-639. PMID: 35716955.
    Citations:    Fields:    
  6. Chaker L, Razvi S, Bensenor IM, Azizi F, Pearce EN, Peeters RP. Publisher Correction: Hypothyroidism. Nat Rev Dis Primers. 2022 Jun 10; 8(1):39. PMID: 35688906.
    Citations:    Fields:    
  7. Khan SR, Vanoverschelde A, Lahousse L, Peeters RP, van Hagen PM, Brusselle G, Chaker L, Dalm VASH. Serum Immunoglobulins, Pneumonia Risk, and Lung Function in Middle-Aged and Older Individuals: A Population-Based Cohort Study. Front Immunol. 2022; 13:868973. PMID: 35757724; PMCID: PMC9215210.
    Citations:    Fields:    Translation:Humans
  8. van der Burgh AC, Khan SR, Neggers SJCMM, Hoorn EJ, Chaker L. The role of serum testosterone and dehydroepiandrosterone sulfate in kidney function and clinical outcomes in chronic kidney disease: a systematic review and meta-analysis. Endocr Connect. 2022 Jun 01; 11(6). PMID: 35551117; PMCID: PMC9254301.
    Citations:    
  9. Chaker L, Razvi S, Bensenor IM, Azizi F, Pearce EN, Peeters RP. Hypothyroidism. Nat Rev Dis Primers. 2022 05 19; 8(1):30. PMID: 35589725.
    Citations:    Fields:    Translation:Humans
  10. Roa Dueñas OH, Van der Burgh AC, Ittermann T, Ligthart S, Ikram MA, Peeters R, Chaker L. Thyroid Function and the Risk of Prediabetes and Type 2 Diabetes. J Clin Endocrinol Metab. 2022 05 17; 107(6):1789-1798. PMID: 35137143; PMCID: PMC9315162.
    Citations: 3     Fields:    Translation:Humans
  11. van der Burgh AC, Geurts S, Ikram MA, Hoorn EJ, Kavousi M, Chaker L. Bidirectional Association Between Kidney Function and Atrial Fibrillation: A Population-Based Cohort Study. J Am Heart Assoc. 2022 05 17; 11(10):e025303. PMID: 35579615; PMCID: PMC9238570.
    Citations:    Fields:    Translation:Humans
  12. Geurts S, van der Burgh AC, Bos MM, Ikram MA, Stricker BHC, Deckers JW, Hoorn EJ, Chaker L, Kavousi M. Disentangling the association between kidney function and atrial fibrillation: a bidirectional Mendelian randomization study. Int J Cardiol. 2022 05 15; 355:15-22. PMID: 35278573.
    Citations:    Fields:    Translation:Humans
  13. Toloza FJK, Derakhshan A, Männistö T, Bliddal S, Popova PV, Carty DM, Chen L, Taylor P, Mosso L, Oken E, Suvanto E, Itoh S, Kishi R, Bassols J, Auvinen J, López-Bermejo A, Brown SJ, Boucai L, Hisada A, Yoshinaga J, Shilova E, Grineva EN, Vrijkotte TGM, Sunyer J, Jiménez-Zabala A, Riaño-Galan I, Lopez-Espinosa MJ, Prokop LJ, Singh Ospina N, Brito JP, Rodriguez-Gutierrez R, Alexander EK, Chaker L, Pearce EN, Peeters RP, Feldt-Rasmussen U, Guxens M, Chatzi L, Delles C, Roeters van Lennep JE, Pop VJM, Lu X, Walsh JP, Nelson SM, Korevaar TIM, Maraka S. Association between maternal thyroid function and risk of gestational hypertension and pre-eclampsia: a systematic review and individual-participant data meta-analysis. Lancet Diabetes Endocrinol. 2022 04; 10(4):243-252. PMID: 35255260.
    Citations: 1     Fields:    Translation:Humans
  14. DiCorpo D, LeClair J, Cole JB, Sarnowski C, Ahmadizar F, Bielak LF, Blokstra A, Bottinger EP, Chaker L, Chen YI, Chen Y, de Vries PS, Faquih T, Ghanbari M, Gudmundsdottir V, Guo X, Hasbani NR, Ibi D, Ikram MA, Kavousi M, Leonard HL, Leong A, Mercader JM, Morrison AC, Nadkarni GN, Nalls MA, Noordam R, Preuss M, Smith JA, Trompet S, Vissink P, Yao J, Zhao W, Boerwinkle E, Goodarzi MO, Gudnason V, Jukema JW, Kardia SLR, Loos RJF, Liu CT, Manning AK, Mook-Kanamori D, Pankow JS, Picavet HSJ, Sattar N, Simonsick EM, Verschuren WMM, Willems van Dijk K, Florez JC, Rotter JI, Meigs JB, Dupuis J, Udler MS. Type 2 Diabetes Partitioned Polygenic Scores Associate With Disease Outcomes in 454,193 Individuals Across 13 Cohorts. Diabetes Care. 2022 03 01; 45(3):674-683. PMID: 35085396; PMCID: PMC8918228.
    Citations:    Fields:    Translation:Humans
  15. Syrogiannouli L, Wildisen L, Meuwese C, Bauer DC, Cappola AR, Gussekloo J, den Elzen WPJ, Trompet S, Westendorp RGJ, Jukema JW, Ferrucci L, Ceresini G, Åsvold BO, Chaker L, Peeters RP, Imaizumi M, Ohishi W, Vaes B, Völzke H, Sgarbi JA, Walsh JP, Dullaart RPF, Bakker SJL, Iacoviello M, Rodondi N, Del Giovane C. Incorporating Baseline Outcome Data in Individual Participant Data Meta-Analysis of Non-randomized Studies. Front Psychiatry. 2022; 13:774251. PMID: 35273528; PMCID: PMC8902696.
    Citations:    
  16. van der Burgh AC, Stricker BH, Rizopoulos D, Ikram MA, Hoorn EJ, Chaker L. Kidney function and the risk of sudden cardiac death in the general population. Clin Kidney J. 2022 Aug; 15(8):1524-1533. PMID: 35892020; PMCID: PMC9308098.
    Citations:    
  17. Fani L, Roa Dueñas O, Bos D, Vernooij MW, Klaver CCW, Ikram MK, Peeters RP, Ikram MA, Chaker L. Thyroid Status and Brain Circulation: The Rotterdam Study. J Clin Endocrinol Metab. 2022 02 17; 107(3):e1293-e1302. PMID: 34634119; PMCID: PMC8851919.
    Citations: 1     Fields:    Translation:Humans
  18. de Haan A, Ahmadizar F, van der Most PJ, Thio CHL, Kamali Z, Ani A, Ghanbari M, Chaker L, van Meurs J, Ikram MK, van Goor H, Bakker SJL, van der Harst P, Snieder H, Kavousi M, Pasch A, Eijgelsheim M, de Borst MH. Genetic Determinants of Serum Calcification Propensity and Cardiovascular Outcomes in the General Population. Front Cardiovasc Med. 2021; 8:809717. PMID: 35097025; PMCID: PMC8795369.
    Citations:    
  19. Khan SR, Peeters RP, van Hagen PM, Dalm V, Chaker L. Determinants and Clinical Implications of Thyroid Peroxidase Antibodies in Middle-Aged and Elderly Individuals: The Rotterdam Study. Thyroid. 2022 01; 32(1):78-89. PMID: 34779279.
    Citations:    Fields:    Translation:Humans
  20. Zhou W, Brumpton B, Kabil O, Gudmundsson J, Thorleifsson G, Weinstock J, Zawistowski M, Nielsen JB, Chaker L, Medici M, Teumer A, Naitza S, Sanna S, Schultheiss UT, Cappola A, Karjalainen J, Kurki M, Oneka M, Taylor P, Fritsche LG, Graham SE, Wolford BN, Overton W, Rasheed H, Haug EB, Gabrielsen ME, Skogholt AH, Surakka I, Davey Smith G, Pandit A, Roychowdhury T, Hornsby WE, Jonasson JG, Senter L, Liyanarachchi S, Ringel MD, Xu L, Kiemeney LA, He H, Netea-Maier RT, Mayordomo JI, Plantinga TS, Hrafnkelsson J, Hjartarson H, Sturgis EM, Palotie A, Daly M, Citterio CE, Arvan P, Brummett CM, Boehnke M, de la Chapelle A, Stefansson K, Hveem K, Willer CJ, Åsvold BO. Author Correction: GWAS of thyroid stimulating hormone highlights the pleiotropic effects and inverse association with thyroid cancer. Nat Commun. 2021 Dec 16; 12(1):7354. PMID: 34916535.
    Citations:    Fields:    
  21. Tin A, Schlosser P, Matias-Garcia PR, Thio CHL, Joehanes R, Liu H, Yu Z, Weihs A, Hoppmann A, Grundner-Culemann F, Min JL, Kuhns VLH, Adeyemo AA, Agyemang C, Ärnlöv J, Aziz NA, Baccarelli A, Bochud M, Brenner H, Bressler J, Breteler MMB, Carmeli C, Chaker L, Coresh J, Corre T, Correa A, Cox SR, Delgado GE, Eckardt KU, Ekici AB, Endlich K, Floyd JS, Fraszczyk E, Gao X, Gào X, Gelber AC, Ghanbari M, Ghasemi S, Gieger C, Greenland P, Grove ML, Harris SE, Hemani G, Henneman P, Herder C, Horvath S, Hou L, Hurme MA, Hwang SJ, Kardia SLR, Kasela S, Kleber ME, Koenig W, Kooner JS, Kronenberg F, Kühnel B, Ladd-Acosta C, Lehtimäki T, Lind L, Liu D, Lloyd-Jones DM, Lorkowski S, Lu AT, Marioni RE, März W, McCartney DL, Meeks KAC, Milani L, Mishra PP, Nauck M, Nowak C, Peters A, Prokisch H, Psaty BM, Raitakari OT, Ratliff SM, Reiner AP, Schöttker B, Schwartz J, Sedaghat S, Smith JA, Sotoodehnia N, Stocker HR, Stringhini S, Sundström J, Swenson BR, van Meurs JBJ, van Vliet-Ostaptchouk JV, Venema A, Völker U, Winkelmann J, Wolffenbuttel BHR, Zhao W, Zheng Y, Loh M, Snieder H, Waldenberger M, Levy D, Akilesh S, Woodward OM, Susztak K, Teumer A, Köttgen A. Epigenome-wide association study of serum urate reveals insights into urate co-regulation and the SLC2A9 locus. Nat Commun. 2021 12 09; 12(1):7173. PMID: 34887389; PMCID: PMC8660809.
    Citations:    Fields:    Translation:HumansCells
  22. Schlosser P, Tin A, Matias-Garcia PR, Thio CHL, Joehanes R, Liu H, Weihs A, Yu Z, Hoppmann A, Grundner-Culemann F, Min JL, Adeyemo AA, Agyemang C, Ärnlöv J, Aziz NA, Baccarelli A, Bochud M, Brenner H, Breteler MMB, Carmeli C, Chaker L, Chambers JC, Cole SA, Coresh J, Corre T, Correa A, Cox SR, de Klein N, Delgado GE, Domingo-Relloso A, Eckardt KU, Ekici AB, Endlich K, Evans KL, Floyd JS, Fornage M, Franke L, Fraszczyk E, Gao X, Gào X, Ghanbari M, Ghasemi S, Gieger C, Greenland P, Grove ML, Harris SE, Hemani G, Henneman P, Herder C, Horvath S, Hou L, Hurme MA, Hwang SJ, Jarvelin MR, Kardia SLR, Kasela S, Kleber ME, Koenig W, Kooner JS, Kramer H, Kronenberg F, Kühnel B, Lehtimäki T, Lind L, Liu D, Liu Y, Lloyd-Jones DM, Lohman K, Lorkowski S, Lu AT, Marioni RE, März W, McCartney DL, Meeks KAC, Milani L, Mishra PP, Nauck M, Navas-Acien A, Nowak C, Peters A, Prokisch H, Psaty BM, Raitakari OT, Ratliff SM, Reiner AP, Rosas SE, Schöttker B, Schwartz J, Sedaghat S, Smith JA, Sotoodehnia N, Stocker HR, Stringhini S, Sundström J, Swenson BR, Tellez-Plaza M, van Meurs JBJ, van Vliet-Ostaptchouk JV, Venema A, Verweij N, Walker RM, Wielscher M, Winkelmann J, Wolffenbuttel BHR, Zhao W, Zheng Y, Loh M, Snieder H, Levy D, Waldenberger M, Susztak K, Köttgen A, Teumer A. Meta-analyses identify DNA methylation associated with kidney function and damage. Nat Commun. 2021 12 09; 12(1):7174. PMID: 34887417; PMCID: PMC8660832.
    Citations: 1     Fields:    Translation:HumansCells
  23. van Vliet NA, Bos MM, Thesing CS, Chaker L, Pietzner M, Houtman E, Neville MJ, Li-Gao R, Trompet S, Mustafa R, Ahmadizar F, Beekman M, Bot M, Budde K, Christodoulides C, Dehghan A, Delles C, Elliott P, Evangelou M, Gao H, Ghanbari M, van Herwaarden AE, Ikram MA, Jaeger M, Jukema JW, Karaman I, Karpe F, Kloppenburg M, Meessen JMTA, Meulenbelt I, Milaneschi Y, Mooijaart SP, Mook-Kanamori DO, Netea MG, Netea-Maier RT, Peeters RP, Penninx BWJH, Sattar N, Slagboom PE, Suchiman HED, Völzke H, Willems van Dijk K, Noordam R, van Heemst D. Higher thyrotropin leads to unfavorable lipid profile and somewhat higher cardiovascular disease risk: evidence from multi-cohort Mendelian randomization and metabolomic profiling. BMC Med. 2021 11 03; 19(1):266. PMID: 34727949; PMCID: PMC8565073.
    Citations: 4     Fields:    Translation:Humans
  24. van der Burgh AC, Rizopoulos D, Ikram MA, Hoorn EJ, Chaker L. Determinants of the Evolution of Kidney Function With Age. Kidney Int Rep. 2021 Dec; 6(12):3054-3063. PMID: 34901574; PMCID: PMC8640542.
    Citations: 2     
  25. Khan SR, Chaker L, Ikram MA, Peeters RP, van Hagen PM, Dalm VASH. Determinants and Reference Ranges of Serum Immunoglobulins in Middle-Aged and Elderly Individuals: a Population-Based Study. J Clin Immunol. 2021 11; 41(8):1902-1914. PMID: 34505230; PMCID: PMC8604889.
    Citations: 4     Fields:    Translation:Humans
  26. Wright K, Chaker L, Pacione D, Sam K, Feelders R, Xia Y, Agrawal N. Determinants of Surgical Remission in Prolactinomas: A Systematic Review and Meta-Analysis. World Neurosurg. 2021 10; 154:e349-e369. PMID: 34325023.
    Citations: 1     Fields:    Translation:Humans
  27. Kus A, Kjaergaard AD, Marouli E, Del Greco M F, Sterenborg RBTM, Chaker L, Peeters RP, Bednarczuk T, Åsvold BO, Burgess S, Deloukas P, Teumer A, Ellervik C, Medici M. Thyroid Function and Mood Disorders: A Mendelian Randomization Study. Thyroid. 2021 08; 31(8):1171-1181. PMID: 33899528; PMCID: PMC7612998.
    Citations: 1     Fields:    Translation:Humans
  28. van der Burgh AC, Hoorn EJ, Chaker L. Removing Race From Kidney Function Estimates. JAMA. 2021 05 18; 325(19):2018. PMID: 34003230.
    Citations:    Fields:    
  29. Khan SR, van der Burgh AC, Peeters RP, van Hagen PM, Dalm VASH, Chaker L. Determinants of Serum Immunoglobulin Levels: A Systematic Review and Meta-Analysis. Front Immunol. 2021; 12:664526. PMID: 33897714.
    Citations: 4     Fields:    Translation:Humans
  30. Roa Dueñas OH, Koolhaas C, Voortman T, Franco OH, Ikram MA, Peeters RP, Chaker L. Thyroid Function and Physical Activity: A Population-Based Cohort Study. Thyroid. 2021 06; 31(6):870-875. PMID: 33198599.
    Citations: 2     Fields:    Translation:Humans
  31. Gorski M, Jung B, Li Y, Matias-Garcia PR, Wuttke M, Coassin S, Thio CHL, Kleber ME, Winkler TW, Wanner V, Chai JF, Chu AY, Cocca M, Feitosa MF, Ghasemi S, Hoppmann A, Horn K, Li M, Nutile T, Scholz M, Sieber KB, Teumer A, Tin A, Wang J, Tayo BO, Ahluwalia TS, Almgren P, Bakker SJL, Banas B, Bansal N, Biggs ML, Boerwinkle E, Bottinger EP, Brenner H, Carroll RJ, Chalmers J, Chee ML, Chee ML, Cheng CY, Coresh J, de Borst MH, Degenhardt F, Eckardt KU, Endlich K, Franke A, Freitag-Wolf S, Gampawar P, Gansevoort RT, Ghanbari M, Gieger C, Hamet P, Ho K, Hofer E, Holleczek B, Xian Foo VH, Hutri-Kähönen N, Hwang SJ, Ikram MA, Josyula NS, Kähönen M, Khor CC, Koenig W, Kramer H, Krämer BK, Kühnel B, Lange LA, Lehtimäki T, Lieb W, Loos RJF, Lukas MA, Lyytikäinen LP, Meisinger C, Meitinger T, Melander O, Milaneschi Y, Mishra PP, Mononen N, Mychaleckyj JC, Nadkarni GN, Nauck M, Nikus K, Ning B, Nolte IM, O'Donoghue ML, Orho-Melander M, Pendergrass SA, Penninx BWJH, Preuss MH, Psaty BM, Raffield LM, Raitakari OT, Rettig R, Rheinberger M, Rice KM, Rosenkranz AR, Rossing P, Rotter JI, Sabanayagam C, Schmidt H, Schmidt R, Schöttker B, Schulz CA, Sedaghat S, Shaffer CM, Strauch K, Szymczak S, Taylor KD, Tremblay J, Chaker L, van der Harst P, van der Most PJ, Verweij N, Völker U, Waldenberger M, Wallentin L, Waterworth DM, White HD, Wilson JG, Wong TY, Woodward M, Yang Q, Yasuda M, Yerges-Armstrong LM, Zhang Y, Snieder H, Wanner C, Böger CA, Köttgen A, Kronenberg F, Pattaro C, Heid IM. Meta-analysis uncovers genome-wide significant variants for rapid kidney function decline. Kidney Int. 2021 04; 99(4):926-939. PMID: 33137338; PMCID: PMC8010357.
    Citations: 8     Fields:    Translation:Humans
  32. Kus A, Marouli E, Del Greco M F, Chaker L, Bednarczuk T, Peeters RP, Teumer A, Medici M, Deloukas P. Variation in Normal Range Thyroid Function Affects Serum Cholesterol Levels, Blood Pressure, and Type 2 Diabetes Risk: A Mendelian Randomization Study. Thyroid. 2021 05; 31(5):721-731. PMID: 32746749.
    Citations: 10     Fields:    Translation:Humans
  33. Zhou W, Brumpton B, Kabil O, Gudmundsson J, Thorleifsson G, Weinstock J, Zawistowski M, Nielsen JB, Chaker L, Medici M, Teumer A, Naitza S, Sanna S, Schultheiss UT, Cappola A, Karjalainen J, Kurki M, Oneka M, Taylor P, Fritsche LG, Graham SE, Wolford BN, Overton W, Rasheed H, Haug EB, Gabrielsen ME, Skogholt AH, Surakka I, Davey Smith G, Pandit A, Roychowdhury T, Hornsby WE, Jonasson JG, Senter L, Liyanarachchi S, Ringel MD, Xu L, Kiemeney LA, He H, Netea-Maier RT, Mayordomo JI, Plantinga TS, Hrafnkelsson J, Hjartarson H, Sturgis EM, Palotie A, Daly M, Citterio CE, Arvan P, Brummett CM, Boehnke M, de la Chapelle A, Stefansson K, Hveem K, Willer CJ, Åsvold BO. GWAS of thyroid stimulating hormone highlights pleiotropic effects and inverse association with thyroid cancer. Nat Commun. 2020 08 07; 11(1):3981. PMID: 32769997.
    Citations: 12     Fields:    Translation:Humans
  34. Marouli E, Kus A, Del Greco M F, Chaker L, Peeters R, Teumer A, Deloukas P, Medici M. Thyroid Function Affects the Risk of Stroke via Atrial Fibrillation: A Mendelian Randomization Study. J Clin Endocrinol Metab. 2020 08 01; 105(8). PMID: 32374820; PMCID: PMC7316221.
    Citations: 15     Fields:    Translation:Humans
  35. Kus A, Chaker L, Teumer A, Peeters RP, Medici M. The Genetic Basis of Thyroid Function: Novel Findings and New Approaches. J Clin Endocrinol Metab. 2020 06 01; 105(6). PMID: 32271924.
    Citations: 14     Fields:    Translation:Humans
  36. Derakhshan A, Peeters RP, Taylor PN, Bliddal S, Carty DM, Meems M, Vaidya B, Chen L, Knight BA, Ghafoor F, Popova PV, Mosso L, Oken E, Suvanto E, Hisada A, Yoshinaga J, Brown SJ, Bassols J, Auvinen J, Bramer WM, López-Bermejo A, Dayan CM, French R, Boucai L, Vafeiadi M, Grineva EN, Pop VJM, Vrijkotte TG, Chatzi L, Sunyer J, Jiménez-Zabala A, Riaño I, Rebagliato M, Lu X, Pirzada A, Männistö T, Delles C, Feldt-Rasmussen U, Alexander EK, Nelson SM, Chaker L, Pearce EN, Guxens M, Steegers EAP, Walsh JP, Korevaar TIM. Association of maternal thyroid function with birthweight: a systematic review and individual-participant data meta-analysis. Lancet Diabetes Endocrinol. 2020 06; 8(6):501-510. PMID: 32445737; PMCID: PMC8168324.
    Citations: 28     Fields:    Translation:Humans
  37. Bano A, Chaker L, Muka T, Mattace-Raso FUS, Bally L, Franco OH, Peeters RP, Razvi S. Thyroid Function and the Risk of Fibrosis of the Liver, Heart, and Lung in Humans: A Systematic Review and Meta-Analysis. Thyroid. 2020 06; 30(6):806-820. PMID: 31910097.
    Citations: 7     Fields:    Translation:Humans
  38. Nelson RG, Grams ME, Ballew SH, Sang Y, Azizi F, Chadban SJ, Chaker L, Dunning SC, Fox C, Hirakawa Y, Iseki K, Ix J, Jafar TH, Köttgen A, Naimark DMJ, Ohkubo T, Prescott GJ, Rebholz CM, Sabanayagam C, Sairenchi T, Schöttker B, Shibagaki Y, Tonelli M, Zhang L, Gansevoort RT, Matsushita K, Woodward M, Coresh J, Shalev V. Development of Risk Prediction Equations for Incident Chronic Kidney Disease. JAMA. 2019 12 03; 322(21):2104-2114. PMID: 31703124; PMCID: PMC6865298.
    Citations: 36     Fields:    Translation:Humans
  39. Bano A, Chaker L, Mattace-Raso FUS, Terzikhan N, Kavousi M, Ikram MA, Peeters RP, Franco OH. Thyroid function and life expectancy with and without noncommunicable diseases: A population-based study. PLoS Med. 2019 10; 16(10):e1002957. PMID: 31652264; PMCID: PMC6814213.
    Citations: 2     Fields:    Translation:Humans
  40. Korevaar TIM, Derakhshan A, Taylor PN, Meima M, Chen L, Bliddal S, Carty DM, Meems M, Vaidya B, Shields B, Ghafoor F, Popova PV, Mosso L, Oken E, Suvanto E, Hisada A, Yoshinaga J, Brown SJ, Bassols J, Auvinen J, Bramer WM, López-Bermejo A, Dayan C, Boucai L, Vafeiadi M, Grineva EN, Tkachuck AS, Pop VJM, Vrijkotte TG, Guxens M, Chatzi L, Sunyer J, Jiménez-Zabala A, Riaño I, Murcia M, Lu X, Mukhtar S, Delles C, Feldt-Rasmussen U, Nelson SM, Alexander EK, Chaker L, Männistö T, Walsh JP, Pearce EN, Steegers EAP, Peeters RP. Association of Thyroid Function Test Abnormalities and Thyroid Autoimmunity With Preterm Birth: A Systematic Review and Meta-analysis. JAMA. 2019 08 20; 322(7):632-641. PMID: 31429897; PMCID: PMC6704759.
    Citations: 55     Fields:    Translation:Humans
  41. Bano A, Chaker L, de Maat MPM, Atiq F, Kavousi M, Franco OH, Mattace-Raso FUS, Leebeek FWG, Peeters RP. Thyroid Function and Cardiovascular Disease: The Mediating Role of Coagulation Factors. J Clin Endocrinol Metab. 2019 08 01; 104(8):3203-3212. PMID: 30938758.
    Citations: 9     Fields:    Translation:Humans
  42. Teumer A, Chaker L, Groeneweg S, Li Y, Di Munno C, Barbieri C, Schultheiss UT, Traglia M, Ahluwalia TS, Akiyama M, Appel EVR, Arking DE, Arnold A, Astrup A, Beekman M, Beilby JP, Bekaert S, Boerwinkle E, Brown SJ, De Buyzere M, Campbell PJ, Ceresini G, Cerqueira C, Cucca F, Deary IJ, Deelen J, Eckardt KU, Ekici AB, Eriksson JG, Ferrrucci L, Fiers T, Fiorillo E, Ford I, Fox CS, Fuchsberger C, Galesloot TE, Gieger C, Gögele M, De Grandi A, Grarup N, Greiser KH, Haljas K, Hansen T, Harris SE, van Heemst D, den Heijer M, Hicks AA, den Hollander W, Homuth G, Hui J, Ikram MA, Ittermann T, Jensen RA, Jing J, Jukema JW, Kajantie E, Kamatani Y, Kasbohm E, Kaufman JM, Kiemeney LA, Kloppenburg M, Kronenberg F, Kubo M, Lahti J, Lapauw B, Li S, Liewald DCM, Lim EM, Linneberg A, Marina M, Mascalzoni D, Matsuda K, Medenwald D, Meisinger C, Meulenbelt I, De Meyer T, Meyer Zu Schwabedissen HE, Mikolajczyk R, Moed M, Netea-Maier RT, Nolte IM, Okada Y, Pala M, Pattaro C, Pedersen O, Petersmann A, Porcu E, Postmus I, Pramstaller PP, Psaty BM, Ramos YFM, Rawal R, Redmond P, Richards JB, Rietzschel ER, Rivadeneira F, Roef G, Rotter JI, Sala CF, Schlessinger D, Selvin E, Slagboom PE, Soranzo N, Sørensen TIA, Spector TD, Starr JM, Stott DJ, Taes Y, Taliun D, Tanaka T, Thuesen B, Tiller D, Toniolo D, Uitterlinden AG, Visser WE, Walsh JP, Wilson SG, Wolffenbuttel BHR, Yang Q, Zheng HF, Cappola A, Peeters RP, Naitza S, Völzke H, Sanna S, Köttgen A, Visser TJ, Medici M. Genome-wide analyses identify a role for SLC17A4 and AADAT in thyroid hormone regulation. Nat Commun. 2018 10 26; 9(1):4455. PMID: 30367059; PMCID: PMC6203810.
    Citations: 46     Fields:    Translation:HumansAnimalsCells
  43. Chaker L, Cappola AR, Mooijaart SP, Peeters RP. Clinical aspects of thyroid function during ageing. Lancet Diabetes Endocrinol. 2018 09; 6(9):733-742. PMID: 30017801.
    Citations: 20     Fields:    Translation:Humans
  44. McAninch EA, Rajan KB, Evans DA, Jo S, Chaker L, Peeters RP, Bennett DA, Mash DC, Bianco AC. A Common DIO2 Polymorphism and Alzheimer Disease Dementia in African and European Americans. J Clin Endocrinol Metab. 2018 05 01; 103(5):1818-1826. PMID: 29481662; PMCID: PMC6276710.
    Citations: 18     Fields:    Translation:Humans
  45. Massolt ET, Chaker L, Visser TJ, Gillis AJM, Dorssers LCJ, Beukhof CM, Kam BLR, Franssen GJ, Brigante G, van Ginhoven TM, Visser WE, Looijenga LHJ, Peeters RP. Serum microRNA profiles in athyroid patients on and off levothyroxine therapy. PLoS One. 2018; 13(4):e0194259. PMID: 29649216.
    Citations: 3     Fields:    Translation:Humans
  46. Bos D, Bano A, Hofman A, VanderWeele TJ, Kavousi M, Franco OH, Vernooij MW, Peeters RP, Ikram MA, Chaker L. Thyroid function and atrial fibrillation: Is there a mediating role for epicardial adipose tissue? Clin Epidemiol. 2018; 10:225-234. PMID: 29535556; PMCID: PMC5841949.
    Citations:    
  47. Korevaar TIM, Pop VJ, Chaker L, Goddijn M, de Rijke YB, Bisschop PH, Broeren MA, Jaddoe VWV, Medici M, Visser TJ, Steegers EAP, Vrijkotte TG, Peeters RP. Dose Dependency and a Functional Cutoff for TPO-Antibody Positivity During Pregnancy. J Clin Endocrinol Metab. 2018 02 01; 103(2):778-789. PMID: 29240902.
    Citations: 17     Fields:    Translation:Humans
  48. Chaker L, Bianco AC, Jonklaas J, Peeters RP. Hypothyroidism and hypertension: fact or myth? - Authors' reply. Lancet. 2018 01 06; 391(10115):30. PMID: 29323655.
    Citations: 2     Fields:    Translation:Humans
  49. Bano A, Chaker L, Schoufour J, Ikram MA, Kavousi M, Franco OH, Peeters RP, Mattace-Raso FUS. High Circulating Free Thyroxine Levels May Increase the Risk of Frailty: The Rotterdam Study. J Clin Endocrinol Metab. 2018 01 01; 103(1):328-335. PMID: 29126162.
    Citations: 9     Fields:    Translation:Humans
  50. Bano A, Dhana K, Chaker L, Kavousi M, Ikram MA, Mattace-Raso FUS, Peeters RP, Franco OH. Association of Thyroid Function With Life Expectancy With and Without Cardiovascular Disease: The Rotterdam Study. JAMA Intern Med. 2017 11 01; 177(11):1650-1657. PMID: 28975207; PMCID: PMC5710266.
    Citations: 20     Fields:    Translation:Humans
  51. Bano A, Chaker L, Mattace-Raso FUS, van der Lugt A, Ikram MA, Franco OH, Peeters RP, Kavousi M. Thyroid Function and the Risk of Atherosclerotic Cardiovascular Morbidity and Mortality: The Rotterdam Study. Circ Res. 2017 Dec 08; 121(12):1392-1400. PMID: 29089349.
    Citations: 26     Fields:    Translation:Humans
  52. Önsesveren I, Barjaktarovic M, Chaker L, de Rijke YB, Jaddoe VWV, van Santen HM, Visser TJ, Peeters RP, Korevaar TIM. Childhood Thyroid Function Reference Ranges and Determinants: A Literature Overview and a Prospective Cohort Study. Thyroid. 2017 11; 27(11):1360-1369. PMID: 28942709.
    Citations: 12     Fields:    Translation:Humans
  53. Korevaar TIM, Chaker L, Peeters RP. Improving the clinical impact of randomised trials in thyroidology. Lancet Diabetes Endocrinol. 2018 07; 6(7):523-525. PMID: 29030202.
    Citations: 6     Fields:    Translation:Humans
  54. Chaker L, Cremers LGM, Korevaar TIM, de Groot M, Dehghan A, Franco OH, Niessen WJ, Ikram MA, Peeters RP, Vernooij MW. Age-dependent association of thyroid function with brain morphology and microstructural organization: evidence from brain imaging. Neurobiol Aging. 2018 01; 61:44-51. PMID: 29032192.
    Citations: 3     Fields:    Translation:Humans
  55. Korevaar TIM, Steegers EAP, Chaker L, Medici M, Jaddoe VWV, Visser TJ, de Rijke YB, Peeters RP. Thyroid Function and Premature Delivery in TPO Antibody-Negative Women: The Added Value of hCG. J Clin Endocrinol Metab. 2017 09 01; 102(9):3360-3367. PMID: 28911134.
    Citations: 6     Fields:    Translation:Humans
  56. Chaker L, Korevaar TIM, Rizopoulos D, Collet TH, Völzke H, Hofman A, Rodondi N, Cappola AR, Peeters RP, Franco OH. Defining Optimal Health Range for Thyroid Function Based on the Risk of Cardiovascular Disease. J Clin Endocrinol Metab. 2017 08 01; 102(8):2853-2861. PMID: 28520952.
    Citations: 12     Fields:    Translation:Humans
  57. Beukhof CM, van Doorn L, Visser TJ, Bins S, Visser WE, van Heerebeek R, van Kemenade FJ, de Rijke YB, de Herder WW, Chaker L, Mathijssen RH, Peeters RP. Sorafenib-Induced Changes in Thyroid Hormone Levels in Patients Treated for Hepatocellular Carcinoma. J Clin Endocrinol Metab. 2017 08 01; 102(8):2922-2929. PMID: 28575418.
    Citations: 2     Fields:    Translation:HumansAnimalsCells
  58. Khan SR, Bano A, Wakkee M, Korevaar TIM, Franco OH, Nijsten TEC, Peeters RP, Chaker L. The association of autoimmune thyroid disease (AITD) with psoriatic disease: a prospective cohort study, systematic review and meta-analysis. Eur J Endocrinol. 2017 Oct; 177(4):347-359. PMID: 28747386.
    Citations: 9     Fields:    Translation:Humans
  59. Medici M, Chaker L, Peeters RP. A Step Forward in Understanding the Relevance of Genetic Variation in Type 2 Deiodinase. J Clin Endocrinol Metab. 2017 05 01; 102(5):1775-1778. PMID: 28482082.
    Citations: 5     Fields:    Translation:Humans
  60. Chaker L, Cappola AR, Rodondi N, Peeters RP. Response to the Letter by Choy. J Clin Endocrinol Metab. 2017 04 01; 102(4):1409-1410. PMID: 28388731.
    Citations:    Fields:    Translation:Humans
  61. Chaker L, Bianco AC, Jonklaas J, Peeters RP. Hypothyroidism. Lancet. 2017 Sep 23; 390(10101):1550-1562. PMID: 28336049; PMCID: PMC6619426.
    Citations: 195     Fields:    
  62. Barjaktarovic M, Korevaar TI, Chaker L, Jaddoe VW, de Rijke YB, Visser TJ, Steegers EA, Peeters RP. The association of maternal thyroid function with placental hemodynamics. Hum Reprod. 2017 03 01; 32(3):653-661. PMID: 28130433.
    Citations: 14     Fields:    Translation:Humans
  63. Chaker L, van den Berg M, Stricker BH, Peeters RP. Response by Chaker et al to Letter Regarding Article, "Thyroid Function and Sudden Cardiac Death: A Prospective Population-Based Cohort Study". Circulation. 2017 02 21; 135(8):e90-e91. PMID: 28223331.
    Citations:    Fields:    Translation:Humans
  64. Korevaar TI, de Rijke YB, Chaker L, Medici M, Jaddoe VW, Steegers EA, Visser TJ, Peeters RP. Stimulation of Thyroid Function by Human Chorionic Gonadotropin During Pregnancy: A Risk Factor for Thyroid Disease and a Mechanism for Known Risk Factors. Thyroid. 2017 03; 27(3):440-450. PMID: 28049387.
    Citations: 14     Fields:    Translation:Humans
  65. Chaker L, Peeters RP. [What is a normal thyroid function?] Ned Tijdschr Geneeskd. 2017; 161:D926. PMID: 28351434.
    Citations: 1     Fields:    Translation:Humans
  66. Korevaar TI, Steegers EA, Pop VJ, Broeren MA, Chaker L, de Rijke YB, Jaddoe VW, Medici M, Visser TJ, Tiemeier H, Peeters RP. Thyroid Autoimmunity Impairs the Thyroidal Response to Human Chorionic Gonadotropin: Two Population-Based Prospective Cohort Studies. J Clin Endocrinol Metab. 2017 01 01; 102(1):69-77. PMID: 27754809.
    Citations: 27     Fields:    Translation:Humans
  67. Bano A, Chaker L, Darweesh SK, Korevaar TI, Mattace-Raso FU, Dehghan A, Franco OH, van der Geest JN, Ikram MA, Peeters RP. Gait patterns associated with thyroid function: The Rotterdam Study. Sci Rep. 2016 12 14; 6:38912. PMID: 27966590.
    Citations: 3     Fields:    Translation:HumansCTClinical Trials
  68. Chaker L, Sedaghat S, Hoorn EJ, Elzen WP, Gussekloo J, Hofman A, Ikram MA, Franco OH, Dehghan A, Peeters RP. The association of thyroid function and the risk of kidney function decline: a population-based cohort study. Eur J Endocrinol. 2016 Dec; 175(6):653-660. PMID: 27926474.
    Citations: 9     Fields:    Translation:HumansPHPublic Health
  69. Chaker L, Ligthart S, Korevaar TI, Hofman A, Franco OH, Peeters RP, Dehghan A. Thyroid function and risk of type 2 diabetes: a population-based prospective cohort study. BMC Med. 2016 Sep 30; 14(1):150. PMID: 27686165.
    Citations: 49     Fields:    
  70. Rieben C, Segna D, da Costa BR, Collet TH, Chaker L, Aubert CE, Baumgartner C, Almeida OP, Hogervorst E, Trompet S, Masaki K, Mooijaart SP, Gussekloo J, Peeters RP, Bauer DC, Aujesky D, Rodondi N. Subclinical Thyroid Dysfunction and the Risk of Cognitive Decline: a Meta-Analysis of Prospective Cohort Studies. J Clin Endocrinol Metab. 2016 12; 101(12):4945-4954. PMID: 27689250; PMCID: PMC6287525.
    Citations: 36     Fields:    Translation:Humans
  71. Korevaar TI, Steegers EA, Chaker L, Medici M, Jaddoe VW, Visser TJ, de Rijke YB, Peeters RP. The Risk of Preeclampsia According to High Thyroid Function in Pregnancy Differs by hCG Concentration. J Clin Endocrinol Metab. 2016 12; 101(12):5037-5043. PMID: 27648965.
    Citations: 5     Fields:    Translation:Humans
  72. Khan SR, Chaker L, Ruiter R, Aerts JG, Hofman A, Dehghan A, Franco OH, Stricker BH, Peeters RP. Thyroid Function and Cancer Risk: The Rotterdam Study. J Clin Endocrinol Metab. 2016 12; 101(12):5030-5036. PMID: 27648963.
    Citations: 30     Fields:    Translation:Humans
  73. Chaker L, Wolters FJ, Bos D, Korevaar TI, Hofman A, van der Lugt A, Koudstaal PJ, Franco OH, Dehghan A, Vernooij MW, Peeters RP, Ikram MA. Thyroid function and the risk of dementia: The Rotterdam Study. Neurology. 2016 Oct 18; 87(16):1688-1695. PMID: 27638924.
    Citations: 25     Fields:    Translation:Humans
  74. Chaker L, Baumgartner C, den Elzen WP, Collet TH, Ikram MA, Blum MR, Dehghan A, Drechsler C, Luben RN, Portegies ML, Iervasi G, Medici M, Stott DJ, Dullaart RP, Ford I, Bremner A, Newman AB, Wanner C, Sgarbi JA, Dörr M, Longstreth WT, Psaty BM, Ferrucci L, Maciel RM, Westendorp RG, Jukema JW, Ceresini G, Imaizumi M, Hofman A, Bakker SJ, Franklyn JA, Khaw KT, Bauer DC, Walsh JP, Razvi S, Gussekloo J, Völzke H, Franco OH, Cappola AR, Rodondi N, Peeters RP. Thyroid Function Within the Reference Range and the Risk of Stroke: An Individual Participant Data Analysis. J Clin Endocrinol Metab. 2016 11; 101(11):4270-4282. PMID: 27603906; PMCID: PMC5095234.
    Citations: 20     Fields:    Translation:Humans
  75. Chaker L, van den Berg ME, Niemeijer MN, Franco OH, Dehghan A, Hofman A, Rijnbeek PR, Deckers JW, Eijgelsheim M, Stricker BH, Peeters RP. Thyroid Function and Sudden Cardiac Death: A Prospective Population-Based Cohort Study. Circulation. 2016 Sep 06; 134(10):713-22. PMID: 27601558.
    Citations: 26     Fields:    Translation:HumansPHPublic Health
  76. Chaker L, Korevaar TI, Medici M, Uitterlinden AG, Hofman A, Dehghan A, Franco OH, Peeters RP. Thyroid Function Characteristics and Determinants: The Rotterdam Study. Thyroid. 2016 09; 26(9):1195-204. PMID: 27484151.
    Citations: 24     Fields:    Translation:Humans
  77. Korevaar TI, Nieboer D, Bisschop PH, Goddijn M, Medici M, Chaker L, de Rijke YB, Jaddoe VW, Visser TJ, Steyerberg EW, Tiemeier H, Vrijkotte TG, Peeters RP. Risk factors and a clinical prediction model for low maternal thyroid function during early pregnancy: two population-based prospective cohort studies. Clin Endocrinol (Oxf). 2016 Dec; 85(6):902-909. PMID: 27384268; PMCID: PMC5495157.
    Citations: 8     Fields:    Translation:Humans
  78. Amin N, Jovanova O, Adams HH, Dehghan A, Kavousi M, Vernooij MW, Peeters RP, de Vrij FM, van der Lee SJ, van Rooij JG, van Leeuwen EM, Chaker L, Demirkan A, Hofman A, Brouwer RW, Kraaij R, Willems van Dijk K, Hankemeier T, van Ijcken WF, Uitterlinden AG, Niessen WJ, Franco OH, Kushner SA, Ikram MA, Tiemeier H, van Duijn CM. Exome-sequencing in a large population-based study reveals a rare Asn396Ser variant in the LIPG gene associated with depressive symptoms. Mol Psychiatry. 2017 04; 22(4):634. PMID: 27502476.
    Citations: 3     Fields:    
  79. Amin N, Jovanova O, Adams HH, Dehghan A, Kavousi M, Vernooij MW, Peeters RP, de Vrij FM, van der Lee SJ, van Rooij JG, van Leeuwen EM, Chaker L, Demirkan A, Hofman A, Brouwer RW, Kraaij R, Willems van Dijk K, Hankemeier T, van Ijcken WF, Uitterlinden AG, Niessen WJ, Franco OH, Kushner SA, Ikram MA, Tiemeier H, van Duijn CM. Exome-sequencing in a large population-based study reveals a rare Asn396Ser variant in the LIPG gene associated with depressive symptoms. Mol Psychiatry. 2017 04; 22(4):537-543. PMID: 27431295.
    Citations: 17     Fields:    Translation:Humans
  80. Korevaar TI, Chaker L, Medici M, de Rijke YB, Jaddoe VW, Steegers EA, Tiemeier H, Visser TJ, Peeters RP. Maternal total T4 during the first half of pregnancy: physiologic aspects and the risk of adverse outcomes in comparison with free T4. Clin Endocrinol (Oxf). 2016 Nov; 85(5):757-763. PMID: 27187054.
    Citations: 14     Fields:    Translation:Humans
  81. Bano A, Chaker L, Plompen EP, Hofman A, Dehghan A, Franco OH, Janssen HL, Darwish Murad S, Peeters RP. Thyroid Function and the Risk of Nonalcoholic Fatty Liver Disease: The Rotterdam Study. J Clin Endocrinol Metab. 2016 08; 101(8):3204-11. PMID: 27270473.
    Citations: 50     Fields:    Translation:Humans
  82. Chaker L, Visser TJ. Thyroid function: Thyroid dysfunction and breast cancer risk - an unfinished story. Nat Rev Endocrinol. 2016 06; 12(6):313-4. PMID: 27020258.
    Citations: 4     Fields:    Translation:Humans
  83. Korevaar TI, Chaker L, Jaddoe VW, Visser TJ, Medici M, Peeters RP. Maternal and Birth Characteristics Are Determinants of Offspring Thyroid Function. J Clin Endocrinol Metab. 2016 Jan; 101(1):206-13. PMID: 26583586.
    Citations: 19     Fields:    Translation:Humans
  84. Korevaar TI, Muetzel R, Medici M, Chaker L, Jaddoe VW, de Rijke YB, Steegers EA, Visser TJ, White T, Tiemeier H, Peeters RP. Association of maternal thyroid function during early pregnancy with offspring IQ and brain morphology in childhood: a population-based prospective cohort study. Lancet Diabetes Endocrinol. 2016 Jan; 4(1):35-43. PMID: 26497402.
    Citations: 109     Fields:    Translation:Humans
  85. Chaker L, Heeringa J, Dehghan A, Medici M, Visser WE, Baumgartner C, Hofman A, Rodondi N, Peeters RP, Franco OH. Normal Thyroid Function and the Risk of Atrial Fibrillation: the Rotterdam Study. J Clin Endocrinol Metab. 2015 Oct; 100(10):3718-24. PMID: 26262438.
    Citations: 38     Fields:    Translation:Humans
  86. Chaker L, Buitendijk GH, Dehghan A, Medici M, Hofman A, Vingerling JR, Franco OH, Klaver CC, Peeters RP. Thyroid function and age-related macular degeneration: a prospective population-based cohort study--the Rotterdam Study. BMC Med. 2015 Apr 23; 13:94. PMID: 25903050.
    Citations: 18     Fields:    Translation:Humans
  87. Chaker L, Baumgartner C, den Elzen WP, Ikram MA, Blum MR, Collet TH, Bakker SJ, Dehghan A, Drechsler C, Luben RN, Hofman A, Portegies ML, Medici M, Iervasi G, Stott DJ, Ford I, Bremner A, Wanner C, Ferrucci L, Newman AB, Dullaart RP, Sgarbi JA, Ceresini G, Maciel RM, Westendorp RG, Jukema JW, Imaizumi M, Franklyn JA, Bauer DC, Walsh JP, Razvi S, Khaw KT, Cappola AR, Völzke H, Franco OH, Gussekloo J, Rodondi N, Peeters RP. Subclinical Hypothyroidism and the Risk of Stroke Events and Fatal Stroke: An Individual Participant Data Analysis. J Clin Endocrinol Metab. 2015 Jun; 100(6):2181-91. PMID: 25856213; PMCID: PMC4454799.
    Citations: 57     Fields:    Translation:Humans
  88. Chaker L, Falla A, van der Lee SJ, Muka T, Imo D, Jaspers L, Colpani V, Mendis S, Chowdhury R, Bramer WM, Pazoki R, Franco OH. The global impact of non-communicable diseases on macro-economic productivity: a systematic review. Eur J Epidemiol. 2015 May; 30(5):357-95. PMID: 25837965; PMCID: PMC4457808.
    Citations: 40     Fields:    Translation:Humans
  89. Schultheiss UT, Teumer A, Medici M, Li Y, Daya N, Chaker L, Homuth G, Uitterlinden AG, Nauck M, Hofman A, Selvin E, Völzke H, Peeters RP, Köttgen A. A genetic risk score for thyroid peroxidase antibodies associates with clinical thyroid disease in community-based populations. J Clin Endocrinol Metab. 2015 May; 100(5):E799-807. PMID: 25719932; PMCID: PMC4422885.
    Citations: 18     Fields:    Translation:Humans
  90. Muka T, Imo D, Jaspers L, Colpani V, Chaker L, van der Lee SJ, Mendis S, Chowdhury R, Bramer WM, Falla A, Pazoki R, Franco OH. The global impact of non-communicable diseases on healthcare spending and national income: a systematic review. Eur J Epidemiol. 2015 Apr; 30(4):251-77. PMID: 25595318.
    Citations: 93     Fields:    Translation:Humans
  91. Jaspers L, Colpani V, Chaker L, van der Lee SJ, Muka T, Imo D, Mendis S, Chowdhury R, Bramer WM, Falla A, Pazoki R, Franco OH. The global impact of non-communicable diseases on households and impoverishment: a systematic review. Eur J Epidemiol. 2015 Mar; 30(3):163-88. PMID: 25527371.
    Citations: 57     Fields:    Translation:Humans
  92. Chaker L, Baumgartner C, Ikram MA, Dehghan A, Medici M, Visser WE, Hofman A, Rodondi N, Peeters RP, Franco OH. Subclinical thyroid dysfunction and the risk of stroke: a systematic review and meta-analysis. Eur J Epidemiol. 2014 Nov; 29(11):791-800. PMID: 25179793.
    Citations: 14     Fields:    Translation:Humans
  93. Medici M, Porcu E, Pistis G, Teumer A, Brown SJ, Jensen RA, Rawal R, Roef GL, Plantinga TS, Vermeulen SH, Lahti J, Simmonds MJ, Husemoen LL, Freathy RM, Shields BM, Pietzner D, Nagy R, Broer L, Chaker L, Korevaar TI, Plia MG, Sala C, Völker U, Richards JB, Sweep FC, Gieger C, Corre T, Kajantie E, Thuesen B, Taes YE, Visser WE, Hattersley AT, Kratzsch J, Hamilton A, Li W, Homuth G, Lobina M, Mariotti S, Soranzo N, Cocca M, Nauck M, Spielhagen C, Ross A, Arnold A, van de Bunt M, Liyanarachchi S, Heier M, Grabe HJ, Masciullo C, Galesloot TE, Lim EM, Reischl E, Leedman PJ, Lai S, Delitala A, Bremner AP, Philips DI, Beilby JP, Mulas A, Vocale M, Abecasis G, Forsen T, James A, Widen E, Hui J, Prokisch H, Rietzschel EE, Palotie A, Feddema P, Fletcher SJ, Schramm K, Rotter JI, Kluttig A, Radke D, Traglia M, Surdulescu GL, He H, Franklyn JA, Tiller D, Vaidya B, de Meyer T, Jørgensen T, Eriksson JG, O'Leary PC, Wichmann E, Hermus AR, Psaty BM, Ittermann T, Hofman A, Bosi E, Schlessinger D, Wallaschofski H, Pirastu N, Aulchenko YS, de la Chapelle A, Netea-Maier RT, Gough SC, Meyer Zu Schwabedissen H, Frayling TM, Kaufman JM, Linneberg A, Räikkönen K, Smit JW, Kiemeney LA, Rivadeneira F, Uitterlinden AG, Walsh JP, Meisinger C, den Heijer M, Visser TJ, Spector TD, Wilson SG, Völzke H, Cappola A, Toniolo D, Sanna S, Naitza S, Peeters RP. Identification of novel genetic Loci associated with thyroid peroxidase antibodies and clinical thyroid disease. PLoS Genet. 2014 Feb; 10(2):e1004123. PMID: 24586183.
    Citations: 55     Fields:    Translation:Humans
  94. Chaker L, Segeren CM, Bot FJ, Maartense E. Haemophagocytic syndrome and Hodgkin's disease variant of Richter's syndrome after fludarabine for CLL. Eur J Haematol. 2010 Jul; 85(1):91-2. PMID: 20331737.
    Citations: 4     Fields:    Translation:Humans
  95. Loudon SE, Passchier J, Chaker L, de Vos S, Fronius M, Harrad RA, Looman CW, Simonsz B, Simonsz HJ. Psychological causes of non-compliance with electronically monitored occlusion therapy for amblyopia. Br J Ophthalmol. 2009 Nov; 93(11):1499-503. PMID: 19661070.
    Citations: 18     Fields:    Translation:Humans
Local representatives can answer questions about the Profiles website or help with editing a profile or issues with profile data. For assistance with this profile: SPH faculty should contact Faculty Affairs at facultyaffairshsph.harvard.edu).
Chaker's Networks
Click the
Explore
buttons for more information and interactive visualizations!
Concepts (246)
Explore
_
Co-Authors (20)
Explore
_
Similar People (60)
Explore
_
Same Department 
Explore
_
Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.