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Tsuyoshi Fukushima, Ph.D., M.D.


Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Hayashi Y, Kawabata KC, Tanaka Y, Uehara Y, Mabuchi Y, Murakami K, Nishiyama A, Kiryu S, Yoshioka Y, Ota Y, Sugiyama T, Mikami K, Tamura M, Fukushima T, Asada S, Takeda R, Kunisaki Y, Fukuyama T, Yokoyama K, Uchida T, Hagihara M, Ohno N, Usuki K, Tojo A, Katayama Y, Goyama S, Arai F, Tamura T, Nagasawa T, Ochiya T, Inoue D, Kitamura T. MDS cells impair osteolineage differentiation of MSCs via extracellular vesicles to suppress normal hematopoiesis. Cell Rep. 2022 05 10; 39(6):110805. PMID: 35545056.
    Citations:    Fields:    Translation:AnimalsCells
  2. Yamashita S, Takeshima H, Kadota Y, Azuma M, Fukushima T, Ogasawara N, Kawano T, Tamura M, Muta J, Saito K, Takeishi G, Mizuguchi A, Watanabe T, Ohta H, Yokogami K. T2-fluid-attenuated inversion recovery mismatch sign in lower grade gliomas: correlation with pathological and molecular findings. Brain Tumor Pathol. 2022 Apr; 39(2):88-98. PMID: 35482260.
    Citations:    Fields:    Translation:Humans
  3. Izumi A, Yamamoto K, Kawaguchi M, Yamashita F, Fukushima T, Kiwaki T, Tanaka H, Yamashita Y, Kataoka H. Insufficiency of hepatocyte growth factor activator inhibitor-1 confers lymphatic invasion of tongue carcinoma cells. Cancer Sci. 2022 Jun; 113(6):2179-2193. PMID: 35332604; PMCID: PMC9207362.
    Citations: 1     Fields:    Translation:HumansAnimals
  4. Yamashita F, Kaieda T, Shimomura T, Kawaguchi M, Lin CY, Johnson MD, Tanaka H, Kiwaki T, Fukushima T, Kataoka H. Role of the polycystic kidney disease domain in matriptase chaperone activity and localization of hepatocyte growth factor activator inhibitor-1. FEBS J. 2022 Jun; 289(12):3422-3439. PMID: 35020274.
    Citations: 1     Fields:    Translation:HumansCells
  5. Tanaka Y, Takeda R, Fukushima T, Mikami K, Tsuchiya S, Tamura M, Adachi K, Umemoto T, Asada S, Watanabe N, Morishita S, Imai M, Nagata M, Araki M, Takizawa H, Fukuyama T, Lamagna C, Masuda ES, Ito R, Goyama S, Komatsu N, Takaku T, Kitamura T. Eliminating chronic myeloid leukemia stem cells by IRAK1/4 inhibitors. Nat Commun. 2022 01 12; 13(1):271. PMID: 35022428; PMCID: PMC8755781.
    Citations: 2     Fields:    Translation:HumansAnimalsCells
  6. Kiwaki T, Nagayasu MA, Yamada N, Kodama Y, Umekita Y, Fukushima T, Kataoka H, Tanaka H. Congenital tracheo-esophageal transition: A previously undescribed tracheo-esophageal malformation that showed direct transition of the trachea to the esophagus. Pathol Int. 2022 Feb; 72(2):144-146. PMID: 34935244.
    Citations:    Fields:    Translation:Humans
  7. Wakizaka K, Khor LW, Annen K, Fukushima T, Furuya M, Taketomi A. Meckel's diverticulum with intraperitoneal hemorrhage in a child detected with screening laparoscopy: a case report. Surg Case Rep. 2021 Dec 20; 7(1):264. PMID: 34928454.
  8. Fukushima T, Tanaka Y, Adachi K, Masuyama N, Tsuchiya A, Asada S, Ishiguro S, Mori H, Seki M, Yachie N, Goyama S, Kitamura T. CRISPR/Cas9-mediated base-editing enables a chain reaction through sequential repair of sgRNA scaffold mutations. Sci Rep. 2021 12 13; 11(1):23889. PMID: 34903756; PMCID: PMC8668876.
    Citations:    Fields:    Translation:HumansCells
  9. Shinkawa N, Horinouchi H, Shinkawa N, Imamura N, Fukushima T. Carbohydrate antigen 19-9-producing splenic cyst: a case report. Radiol Case Rep. 2022 Jan; 17(1):19-22. PMID: 34760035.
  10. Wakizaka K, Homma S, Ichikawa N, Yoshida T, Matsui H, Khor LW, Annen K, Fukushima T, Taketomi A. Lateral lymph node recurrence of rectal cancer with a pathological complete response to chemotherapy confirmed by laparoscopic lateral lymph node dissection: A case report. Asian J Endosc Surg. 2022 Jan; 15(1):216-219. PMID: 34374205.
    Citations:    Fields:    Translation:Humans
  11. Otsuka I, Ueno T, Terada N, Mukai S, Fukushima T, Kiwaki T, Nagano M. Cutaneous metastasis emerging during chemotherapy and progressing during immunotherapy for urothelial carcinoma. IJU Case Rep. 2021 Nov; 4(6):363-366. PMID: 34755057; PMCID: PMC8560435.
  12. Yamamoto K, Yamashita F, Kawaguchi M, Izumi A, Kiwaki T, Kataoka H, Kaneuji T, Yamashita Y, Fukushima T. Decreased prostasin expression is associated with aggressiveness of oral squamous cell carcinoma. Hum Cell. 2021 Sep; 34(5):1434-1445. PMID: 34250582.
    Citations:    Fields:    Translation:HumansCells
  13. Yamamoto K, Maki Y, Sato Y, Tanaka H, Fukushima T, Ushijima J, Furukawa S, Sameshima H, Kataoka H. Multiple cardiac rhabdomyomas not associated with tuberous sclerosis in a dizygotic twins: a case report. J Med Case Rep. 2021 Jul 05; 15(1):334. PMID: 34218815.
    Citations:    Fields:    Translation:Humans
  14. Iwao K, Kawaguchi T, Kimura M, Iwao C, Rikitake M, Aizawa A, Kariya Y, Matsuda M, Miyauchi S, Takajo I, Kiwaki T, Fukushima T, Kataoka H, Suzuki T, Okayama A, Umekita K. Severe Fever with Thrombocytopenia Syndrome Accompanied by Invasive Pulmonary Aspergillosis: An Autopsy Case. Viruses. 2021 06 07; 13(6). PMID: 34200385; PMCID: PMC8226712.
    Citations: 3     Fields:    Translation:HumansAnimalsCells
  15. Fujino T, Goyama S, Sugiura Y, Inoue D, Asada S, Yamasaki S, Matsumoto A, Yamaguchi K, Isobe Y, Tsuchiya A, Shikata S, Sato N, Morinaga H, Fukuyama T, Tanaka Y, Fukushima T, Takeda R, Yamamoto K, Honda H, Nishimura EK, Furukawa Y, Shibata T, Abdel-Wahab O, Suematsu M, Kitamura T. Mutant ASXL1 induces age-related expansion of phenotypic hematopoietic stem cells through activation of Akt/mTOR pathway. Nat Commun. 2021 03 23; 12(1):1826. PMID: 33758188; PMCID: PMC7988019.
    Citations: 13     Fields:    Translation:HumansAnimalsCells
  16. Takeda R, Asada S, Park SJ, Yokoyama A, Becker HJ, Kanai A, Visconte V, Hershberger C, Hayashi Y, Yonezawa T, Tamura M, Fukushima T, Tanaka Y, Fukuyama T, Matsumoto A, Yamasaki S, Nakai K, Yamazaki S, Inaba T, Shibata T, Inoue D, Honda H, Goyama S, Maciejewski JP, Kitamura T. HHEX promotes myeloid transformation in cooperation with mutant ASXL1. Blood. 2020 10 01; 136(14):1670-1684. PMID: 32492700.
    Citations: 4     Fields:    Translation:HumansAnimalsCells
  17. Tanaka Y, Fukushima T, Mikami K, Adachi K, Fukuyama T, Goyama S, Kitamura T. Efficacy of tyrosine kinase inhibitors on a mouse chronic myeloid leukemia model and chronic myeloid leukemia stem cells. Exp Hematol. 2020 10; 90:46-51.e2. PMID: 32910995.
    Citations: 1     Fields:    Translation:HumansAnimalsCells
  18. Fukushima T, Ueda T, Hirato J, Kataoka H. RELA fusion-positive ependymoma accompanied by extensive desmoplasia: a case report. Brain Tumor Pathol. 2020 Oct; 37(4):159-164. PMID: 32754892.
    Citations:    Fields:    Translation:Humans
  19. Kawaguchi M, Yamamoto K, Kataoka H, Izumi A, Yamashita F, Kiwaki T, Nishida T, Camerer E, Fukushima T. Protease-activated receptor-2 accelerates intestinal tumor formation through activation of nuclear factor-?B signaling and tumor angiogenesis in ApcMin/+ mice. Cancer Sci. 2020 Apr; 111(4):1193-1202. PMID: 31997435; PMCID: PMC7156842.
    Citations: 4     Fields:    Translation:HumansAnimalsCells
  20. Fukushima T, Tanaka Y, Hamey FK, Chang CH, Oki T, Asada S, Hayashi Y, Fujino T, Yonezawa T, Takeda R, Kawabata KC, Fukuyama T, Umemoto T, Takubo K, Takizawa H, Goyama S, Ishihama Y, Honda H, Göttgens B, Kitamura T. Discrimination of Dormant and Active Hematopoietic Stem Cells by G0 Marker Reveals Dormancy Regulation by Cytoplasmic Calcium. Cell Rep. 2019 12 17; 29(12):4144-4158.e7. PMID: 31851939.
    Citations: 9     Fields:    Translation:AnimalsCells
  21. Yamashita S, Takeshima H, Matsumoto F, Yamasaki K, Fukushima T, Sakoda H, Nakazato M, Saito K, Mizuguchi A, Watanabe T, Ohta H, Yokogami K. Detection of the KIAA1549-BRAF fusion gene in cells forming microvascular proliferations in pilocytic astrocytoma. PLoS One. 2019; 14(7):e0220146. PMID: 31329636; PMCID: PMC6645544.
    Citations: 3     Fields:    Translation:HumansCells
  22. Kawaguchi M, Yamamoto K, Takeda N, Fukushima T, Yamashita F, Sato K, Kitamura K, Hippo Y, Janetka JW, Kataoka H. Hepatocyte growth factor activator inhibitor-2 stabilizes Epcam and maintains epithelial organization in the mouse intestine. Commun Biol. 2019; 2:11. PMID: 30623107.
    Citations: 7     Translation:Animals
  23. Fukushima T, Uchiyama S, Tanaka H, Kataoka H. Hepatocyte Growth Factor Activator: A Proteinase Linking Tissue Injury with Repair. Int J Mol Sci. 2018 Nov 01; 19(11). PMID: 30388869.
    Citations: 21     Fields:    Translation:HumansAnimals
  24. Fukushima T, Kawaguchi M, Yamamoto K, Yamashita F, Izumi A, Kaieda T, Takezaki Y, Itoh H, Takeshima H, Kataoka H. Aberrant methylation and silencing of the SPINT2 gene in high-grade gliomas. Cancer Sci. 2018 Sep; 109(9):2970-2979. PMID: 29987920.
    Citations: 9     Fields:    Translation:HumansAnimalsCells
  25. Asada S, Goyama S, Inoue D, Shikata S, Takeda R, Fukushima T, Yonezawa T, Fujino T, Hayashi Y, Kawabata KC, Fukuyama T, Tanaka Y, Yokoyama A, Yamazaki S, Kozuka-Hata H, Oyama M, Kojima S, Kawazu M, Mano H, Kitamura T. Mutant ASXL1 cooperates with BAP1 to promote myeloid leukaemogenesis. Nat Commun. 2018 07 16; 9(1):2733. PMID: 30013160.
    Citations: 43     Fields:    Translation:HumansAnimalsCells
  26. Kataoka H, Kawaguchi M, Fukushima T, Shimomura T. Hepatocyte growth factor activator inhibitors (HAI-1 and HAI-2): Emerging key players in epithelial integrity and cancer. Pathol Int. 2018 Mar; 68(3):145-158. PMID: 29431273.
    Citations: 30     Fields:    Translation:HumansAnimalsCells
  27. Yamamoto K, Kawaguchi M, Shimomura T, Izumi A, Konari K, Honda A, Lin CY, Johnson MD, Yamashita Y, Fukushima T, Kataoka H. Hepatocyte growth factor activator inhibitor type-2 (HAI-2)/SPINT2 contributes to invasive growth of oral squamous cell carcinoma cells. Oncotarget. 2018 Feb 20; 9(14):11691-11706. PMID: 29545930.
    Citations: 11     Fields:    
  28. Sakugawa C, Haruyama Y, Tanaka H, Fukushima T, Kawaguchi M, Kataoka H. Prognostic significance of hepatocyte growth factor activator inhibitor type 1 (HAI-1) immunoreactivity in pancreatic ductal adenocarcinoma. BMC Res Notes. 2017 Dec 04; 10(1):674. PMID: 29202869.
    Citations: 3     Fields:    Translation:Humans
  29. Tokumitsu T, Sato Y, Fukushima T, Takeshima H, Sato S, Asada Y. Squash cytology findings of subependymomas: A report of three cases and differential diagnosis. Diagn Cytopathol. 2018 Mar; 46(3):258-262. PMID: 29024543.
    Citations:    Fields:    Translation:Humans
  30. Yonezawa T, Takahashi H, Shikata S, Liu X, Tamura M, Asada S, Fukushima T, Fukuyama T, Tanaka Y, Sawasaki T, Kitamura T, Goyama S. The ubiquitin ligase STUB1 regulates stability and activity of RUNX1 and RUNX1-RUNX1T1. J Biol Chem. 2017 07 28; 292(30):12528-12541. PMID: 28536267.
    Citations: 4     Fields:    Translation:Humans
  31. Kawaguchi M, Yamamoto K, Kanemaru A, Tanaka H, Umezawa K, Fukushima T, Kataoka H. Inhibition of nuclear factor-?B signaling suppresses Spint1-deletion-induced tumor susceptibility in the ApcMin/+ model. Oncotarget. 2016 Oct 18; 7(42):68614-68622. PMID: 27612426; PMCID: PMC5356577.
    Citations: 3     Fields:    Translation:HumansAnimalsCells
  32. Kanemaru A, Yamamoto K, Kawaguchi M, Fukushima T, Lin CY, Johnson MD, Camerer E, Kataoka H. Deregulated matriptase activity in oral squamous cell carcinoma promotes the infiltration of cancer-associated fibroblasts by paracrine activation of protease-activated receptor 2. Int J Cancer. 2017 Jan 01; 140(1):130-141. PMID: 27615543.
    Citations: 14     Fields:    Translation:HumansCells
  33. Kitamura T, Watanabe-Okochi N, Enomoto Y, Nakahara F, Oki T, Komeno Y, Kato N, Doki N, Uchida T, Kagiyama Y, Togami K, Kawabata KC, Nishimura K, Hayashi Y, Nagase R, Saika M, Fukushima T, Asada S, Fujino T, Izawa Y, Horikawa S, Fukuyama T, Tanaka Y, Ono R, Goyama S, Nosaka T, Kitaura J, Inoue D. Novel working hypothesis for pathogenesis of hematological malignancies: combination of mutations-induced cellular phenotypes determines the disease (cMIP-DD). J Biochem. 2016 Jan; 159(1):17-25. PMID: 26590301; PMCID: PMC4882650.
    Citations: 4     Fields:    Translation:HumansAnimalsCells
  34. Kawaguchi M, Kanemaru A, Fukushima T, Yamamoto K, Tanaka H, Haruyama Y, Itoh H, Matsumoto N, Kangawa K, Nakazato M, Kataoka H. Ghrelin administration suppresses inflammation-associated colorectal carcinogenesis in mice. Cancer Sci. 2015 Sep; 106(9):1130-6. PMID: 26094822; PMCID: PMC4582981.
    Citations: 13     Fields:    Translation:Animals
  35. Kawaguchi M, Kanemaru A, Sawaguchi A, Yamamoto K, Baba T, Lin CY, Johnson MD, Fukushima T, Kataoka H. Hepatocyte growth factor activator inhibitor type 1 maintains the assembly of keratin into desmosomes in keratinocytes by regulating protease-activated receptor 2-dependent p38 signaling. Am J Pathol. 2015 Jun; 185(6):1610-23. PMID: 25842366; PMCID: PMC5707200.
    Citations: 11     Fields:    Translation:HumansAnimalsCells
  36. Kawasoe T, Takeshima H, Yamashita S, Mizuguchi S, Fukushima T, Yokogami K, Yamasaki K. Detection of p53 mutations in proliferating vascular cells in glioblastoma multiforme. J Neurosurg. 2015 Feb; 122(2):317-23. PMID: 25415071.
    Citations: 6     Fields:    Translation:Humans
  37. Yorita K, Yonei A, Ayabe T, Nakada H, Nakashima K, Fukushima T, Kataoka H. Posterior mediastinal ganglioneuroma with peripheral replacement by white and brown adipocytes resulting in diagnostic fallacy from a false-positive 18F-2-fluoro-2-deoxyglucose-positron emission tomography finding: a case report. J Med Case Rep. 2014 Oct 15; 8:345. PMID: 25319096.
    Citations: 5     Fields:    Translation:HumansCells
  38. Fukushima T, Annen K, Kawamukai Y, Onuma N, Kawashima M. [Value of the palliative prognostic index, controlling nutritional status, and prognostic nutritional index for objective evaluation during transition from chemotherapy to palliative care in cases of advanced or recurrent gastrointestinal cancer]. Gan To Kagaku Ryoho. 2014 Jul; 41(7):853-6. PMID: 25131871.
    Citations: 1     Fields:    Translation:Humans
  39. Ye J, Kawaguchi M, Haruyama Y, Kanemaru A, Fukushima T, Yamamoto K, Lin CY, Kataoka H. Loss of hepatocyte growth factor activator inhibitor type 1 participates in metastatic spreading of human pancreatic cancer cells in a mouse orthotopic transplantation model. Cancer Sci. 2014 Jan; 105(1):44-51. PMID: 24147538.
    Citations: 22     Fields:    Translation:HumansAnimalsCells
  40. Hoshiko S, Kawaguchi M, Fukushima T, Haruyama Y, Yorita K, Tanaka H, Seiki M, Inatsu H, Kitamura K, Kataoka H. Hepatocyte growth factor activator inhibitor type 1 is a suppressor of intestinal tumorigenesis. Cancer Res. 2013 Apr 15; 73(8):2659-70. PMID: 23447577.
    Citations: 25     Fields:    Translation:AnimalsCells
  41. Kohama K, Kawaguchi M, Fukushima T, Lin CY, Kataoka H. Regulation of pericellular proteolysis by hepatocyte growth factor activator inhibitor type 1 (HAI-1) in trophoblast cells. Hum Cell. 2012 Dec; 25(4):100-10. PMID: 23248048.
    Citations: 6     Fields:    Translation:HumansAnimalsCells
  42. Yamagata Y, Aikou S, Fukushima T, Kataoka H, Seto Y, Esumi H, Kaminishi M, Goldenring JR, Nomura S. Loss of HGF activator inhibits foveolar hyperplasia induced by oxyntic atrophy without altering gastrin levels. Am J Physiol Gastrointest Liver Physiol. 2012 Dec 01; 303(11):G1254-61. PMID: 23064758.
    Citations:    Fields:    Translation:AnimalsCells
  43. Baba T, Kawaguchi M, Fukushima T, Sato Y, Orikawa H, Yorita K, Tanaka H, Lin CY, Sakoda S, Kataoka H. Loss of membrane-bound serine protease inhibitor HAI-1 induces oral squamous cell carcinoma cells' invasiveness. J Pathol. 2012 Oct; 228(2):181-92. PMID: 22262311.
    Citations: 18     Fields:    Translation:HumansAnimalsCells
  44. Fukushima T, Kawaguchi M, Yorita K, Tanaka H, Takeshima H, Umezawa K, Kataoka H. Antitumor effect of dehydroxymethylepoxyquinomicin, a small molecule inhibitor of nuclear factor-?B, on glioblastoma. Neuro Oncol. 2012 Jan; 14(1):19-28. PMID: 21968049.
    Citations: 18     Fields:    Translation:HumansAnimalsCells
  45. Kawaguchi M, Takeda N, Hoshiko S, Yorita K, Baba T, Sawaguchi A, Nezu Y, Yoshikawa T, Fukushima T, Kataoka H. Membrane-bound serine protease inhibitor HAI-1 is required for maintenance of intestinal epithelial integrity. Am J Pathol. 2011 Oct; 179(4):1815-26. PMID: 21840293; PMCID: PMC3181355.
    Citations: 26     Fields:    Translation:HumansAnimalsCells
  46. Yamashita S, Yokogami K, Niibo T, Takeishi G, Ikeda T, Miyata S, Uehara H, Fukushima T, Nakazato Y, Takeshima H. Oligodendroglial ganglioglioma. Brain Tumor Pathol. 2011 Oct; 28(4):311-6. PMID: 21725645.
    Citations: 2     Fields:    Translation:HumansCells
  47. Takeishi G, Moroki K, Kawasoe T, Fukushima T, Yokogami K, Nabeshima K, Takeshima H. Spontaneous regression and regrowth of central nervous system lymphomatoid granulomatosis: case report. Neurol Med Chir (Tokyo). 2011; 51(11):801-4. PMID: 22123487.
    Citations: 2     Fields:    Translation:Humans
  48. Fukushima T, Kawaguchi M, Yamasaki M, Tanaka H, Yorita K, Kataoka H. Hepatocyte growth factor activator inhibitor type 1 suppresses metastatic pulmonary colonization of pancreatic carcinoma cells. Cancer Sci. 2011 Feb; 102(2):407-13. PMID: 21166957.
    Citations: 14     Fields:    Translation:HumansAnimalsCells
  49. Takahashi N, Fukushima T, Yorita K, Tanaka H, Chijiiwa K, Kataoka H. Dickkopf-1 is overexpressed in human pancreatic ductal adenocarcinoma cells and is involved in invasive growth. Int J Cancer. 2010 Apr 01; 126(7):1611-20. PMID: 19711349.
    Citations: 30     Fields:    Translation:HumansAnimalsCells
  50. Fukushima T, Takeshima H, Kataoka H. Anti-glioma therapy with temozolomide and status of the DNA-repair gene MGMT. Anticancer Res. 2009 Nov; 29(11):4845-54. PMID: 20032445.
    Citations: 39     Fields:    Translation:HumansAnimalsCells
  51. Kawaguchi M, Orikawa H, Baba T, Fukushima T, Kataoka H. Hepatocyte growth factor activator is a serum activator of single-chain precursor macrophage-stimulating protein. FEBS J. 2009 Jul; 276(13):3481-90. PMID: 19456860.
    Citations: 14     Fields:    Translation:HumansAnimalsCells
  52. Cheng H, Fukushima T, Takahashi N, Tanaka H, Kataoka H. Hepatocyte growth factor activator inhibitor type 1 regulates epithelial to mesenchymal transition through membrane-bound serine proteinases. Cancer Res. 2009 Mar 01; 69(5):1828-35. PMID: 19223533.
    Citations: 43     Fields:    Translation:HumansAnimalsCells
  53. Tanaka H, Fukushima T, Yorita K, Kawaguchi M, Kataoka H. Tissue injury alters the site of expression of hepatocyte growth factor activator inhibitor type 1 in bronchial epithelial cells. Hum Cell. 2009 Feb; 22(1):11-7. PMID: 19222607.
    Citations: 3     Fields:    Translation:HumansCells
  54. Okura T, Marutsuka K, Hamada H, Sekimoto T, Fukushima T, Asada Y, Kitamura K, Chosa E. Therapeutic efficacy of intra-articular adrenomedullin injection in antigen-induced arthritis in rabbits. Arthritis Res Ther. 2008; 10(6):R133. PMID: 19014513.
    Citations: 8     Fields:    Translation:Animals
  55. Nagaike K, Kawaguchi M, Takeda N, Fukushima T, Sawaguchi A, Kohama K, Setoyama M, Kataoka H. Defect of hepatocyte growth factor activator inhibitor type 1/serine protease inhibitor, Kunitz type 1 (Hai-1/Spint1) leads to ichthyosis-like condition and abnormal hair development in mice. Am J Pathol. 2008 Nov; 173(5):1464-75. PMID: 18832587; PMCID: PMC2570136.
    Citations: 35     Fields:    Translation:AnimalsCells
  56. Komaki W, Fukushima T, Tanaka H, Itoh H, Chosa E, Kataoka H. Expression of hepatocyte growth factor activator inhibitor type 1 on the epithelial cell surface is regulated by hypoxic and oxidative stresses. Virchows Arch. 2008 Oct; 453(4):347-57. PMID: 18769935.
    Citations: 5     Fields:    Translation:HumansCells
  57. Uehara H, Yamasaki K, Fukushima T, Yamashita A, Marutsuka K, Nakano S, Asada Y, Takeshima H. Intraneural synovial sarcoma originating from the median nerve. Neurol Med Chir (Tokyo). 2008 Feb; 48(2):77-82. PMID: 18296877.
    Citations: 3     Fields:    Translation:Humans
  58. Mukai S, Fukushima T, Naka D, Tanaka H, Osada Y, Kataoka H. Activation of hepatocyte growth factor activator zymogen (pro-HGFA) by human kallikrein 1-related peptidases. FEBS J. 2008 Mar; 275(5):1003-17. PMID: 18221492.
    Citations: 24     Fields:    Translation:HumansCells
  59. Fukushima T, Kataoka H. Roles of insulin-like growth factor binding protein-2 (IGFBP-2) in glioblastoma. Anticancer Res. 2007 Nov-Dec; 27(6A):3685-92. PMID: 17970029.
    Citations: 25     Fields:    Translation:HumansCells
  60. Miyata S, Fukushima T, Kohama K, Tanaka H, Takeshima H, Kataoka H. Roles of Kunitz domains in the anti-invasive effect of hepatocyte growth factor activator inhibitor type 1 in human glioblastoma cells. Hum Cell. 2007 Nov; 20(4):100-6. PMID: 17949349.
    Citations: 7     Fields:    Translation:HumansCells
  61. Kohashi S, Sato Y, Fukushima T, Shomura H, Oshima T, Bairun S, Kondo M, Une Y, Nishihira J, Todo S. Interferon-beta inhibits liver metastases from murine colon 26 carcinoma and its highly metastatic variant. Surg Today. 2007; 37(6):474-81. PMID: 17522764.
    Citations: 1     Fields:    Translation:AnimalsCells
  62. Fukushima T, Tezuka T, Shimomura T, Nakano S, Kataoka H. Silencing of insulin-like growth factor-binding protein-2 in human glioblastoma cells reduces both invasiveness and expression of progression-associated gene CD24. J Biol Chem. 2007 Jun 22; 282(25):18634-18644. PMID: 17475624.
    Citations: 46     Fields:    Translation:HumansCells
  63. Betsunoh H, Mukai S, Akiyama Y, Fukushima T, Minamiguchi N, Hasui Y, Osada Y, Kataoka H. Clinical relevance of hepsin and hepatocyte growth factor activator inhibitor type 2 expression in renal cell carcinoma. Cancer Sci. 2007 Apr; 98(4):491-8. PMID: 17309599.
    Citations: 24     Fields:    Translation:HumansCells
  64. Uchinokura S, Miyata S, Fukushima T, Itoh H, Nakano S, Wakisaka S, Kataoka H. Role of hepatocyte growth factor activator (HGF activator) in invasive growth of human glioblastoma cells in vivo. Int J Cancer. 2006 Feb 01; 118(3):583-92. PMID: 16106403.
    Citations: 15     Fields:    Translation:HumansAnimalsCells
  65. Miyata S, Uchinokura S, Fukushima T, Hamasuna R, Itoh H, Akiyama Y, Nakano S, Wakisaka S, Kataoka H. Diverse roles of hepatocyte growth factor activator inhibitor type 1 (HAI-1) in the growth of glioblastoma cells in vivo. Cancer Lett. 2005 Sep 08; 227(1):83-93. PMID: 16051034.
    Citations: 4     Fields:    Translation:HumansAnimalsCells
  66. Tanaka H, Nagaike K, Takeda N, Itoh H, Kohama K, Fukushima T, Miyata S, Uchiyama S, Uchinokura S, Shimomura T, Miyazawa K, Kitamura N, Yamada G, Kataoka H. Hepatocyte growth factor activator inhibitor type 1 (HAI-1) is required for branching morphogenesis in the chorioallantoic placenta. Mol Cell Biol. 2005 Jul; 25(13):5687-98. PMID: 15964823; PMCID: PMC1157006.
    Citations: 42     Fields:    Translation:Animals
  67. Fukushima T, Nishihira J, Yoshiki T, Iwabuchi K, Iwabuchi C, Yamasaki Y, Kondo M, Sun B, Sato Y, Todo S. Evidence of dual function of macrophage migration inhibitory factor relevant to tumor progression and regression. Int J Mol Med. 2005 Jul; 16(1):119-26. PMID: 15942688.
    Citations: 1     Fields:    Translation:AnimalsCells
  68. Itoh H, Naganuma S, Takeda N, Miyata S, Uchinokura S, Fukushima T, Uchiyama S, Tanaka H, Nagaike K, Shimomura T, Miyazawa K, Yamada G, Kitamura N, Koono M, Kataoka H. Regeneration of injured intestinal mucosa is impaired in hepatocyte growth factor activator-deficient mice. Gastroenterology. 2004 Nov; 127(5):1423-35. PMID: 15521012.
    Citations: 26     Fields:    Translation:AnimalsCells
  69. Nuki Y, Uchinokura S, Miyata S, Fukushima T, Hamasuna R, Nakano S, Wakisaka S, Akiyama Y, Itoh H, Kataoka H. Establishment and characterization of a new human glioblastoma cell line, NYGM. Hum Cell. 2004 Sep; 17(3):145-50. PMID: 15859160.
    Citations: 4     Fields:    Translation:HumansAnimalsCells
  70. Nishihira J, Ishibashi T, Fukushima T, Sun B, Sato Y, Todo S. Macrophage migration inhibitory factor (MIF): Its potential role in tumor growth and tumor-associated angiogenesis. Ann N Y Acad Sci. 2003 May; 995:171-82. PMID: 12814949.
    Citations: 47     Fields:    Translation:HumansAnimals
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.