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Anton Lennikov, Ph.D., M.D.

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Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Saddala MS, Lennikov A, Mukwaya A, Yang X, Tang S, Huang H. Data mining and network analysis reveals C-X-C chemokine receptor type 5 is involved in the pathophysiology of age-related macular degeneration. J Biomol Struct Dyn. 2021 Jul 09; 1-10. PMID: 34243690.
    Citations:    Fields:    
  2. Lachota M, Lennikov A, Malmberg KJ, Zagozdzon R. Bioinformatic Analysis Reveals Central Role for Tumor-Infiltrating Immune Cells in Uveal Melanoma Progression. J Immunol Res. 2021; 2021:9920234. PMID: 34195299.
    Citations:    Fields:    
  3. Hikage F, Lennikov A, Mukwaya A, Lachota M, Ida Y, Utheim TP, Chen DF, Huang H, Ohguro H. NF-?B activation in retinal microglia is involved in the inflammatory and neovascularization signaling in laser-induced choroidal neovascularization in mice. Exp Cell Res. 2021 Jun 01; 403(1):112581. PMID: 33811906.
    Citations: 1     Fields:    
  4. Balt J, Uehara O, Abiko Y, Jamyanjav B, Jav S, Nagasawa T, Mori M, Horie Y, Fujita M, Lennikov A, Ohta T, Hiraoka M, Iwata D, Namba K, Ohno S, Kitaichi N. Alteration of oral flora in Mongolian patients with Behçet's disease: a multicentre study. Clin Exp Rheumatol. 2020 Sep-Oct; 38 Suppl 127(5):80-85. PMID: 33331270.
    Citations: 1     Fields:    Translation:HumansCells
  5. Lennikov A, Mukwaya A, Fan L, Saddala MS, De Falco S, Huang H. Synergistic interactions of PlGF and VEGF contribute to blood-retinal barrier breakdown through canonical NF?B activation. Exp Cell Res. 2020 12 15; 397(2):112347. PMID: 33130176.
    Citations: 1     Fields:    Translation:HumansAnimalsCells
  6. Xeroudaki M, Thangavelu M, Lennikov A, Ratnayake A, Bisevac J, Petrovski G, Fagerholm P, Rafat M, Lagali N. A porous collagen-based hydrogel and implantation method for corneal stromal regeneration and sustained local drug delivery. Sci Rep. 2020 10 09; 10(1):16936. PMID: 33037282.
    Citations: 1     Fields:    Translation:HumansAnimalsCells
  7. Lennikov A, Mukwaya A, Saddala MS, Huang H. Deficiency of C-X-C chemokine receptor type 5 (CXCR5) gene causes dysfunction of retinal pigment epithelium cells. Lab Invest. 2021 02; 101(2):228-244. PMID: 32994482.
    Citations:    Fields:    Translation:AnimalsCells
  8. Huang H, Saddala MS, Lennikov A, Mukwaya A, Fan L. RNA-Seq reveals placental growth factor regulates the human retinal endothelial cell barrier integrity by transforming growth factor (TGF-ß) signaling. Mol Cell Biochem. 2020 Dec; 475(1-2):93-106. PMID: 32813141.
    Citations: 1     Fields:    Translation:HumansCells
  9. Saddala MS, Lennikov A, Huang H. RNA-seq data from C-X-C chemokine receptor type 5 (CXCR5) gene knockout aged mice with retinal degeneration phenotype. Data Brief. 2020 Aug; 31:105915. PMID: 32642521.
    Citations: 1     
  10. Saddala MS, Lennikov A, Mukwaya A, Huang H. Transcriptome-Wide Analysis of CXCR5 Deficient Retinal Pigment Epithelial (RPE) Cells Reveals Molecular Signatures of RPE Homeostasis. Biomedicines. 2020 Jun 01; 8(6). PMID: 32492870.
    Citations: 3     
  11. Huang H, Lennikov A. CXCR5/NRF2 double knockout mice develop retinal degeneration phenotype at early adult age. Exp Eye Res. 2020 07; 196:108061. PMID: 32387618.
    Citations: 1     Fields:    Translation:AnimalsCells
  12. Saddala MS, Lennikov A, Mukwaya A, Yang Y, Hill MA, Lagali N, Huang H. Discovery of novel L-type voltage-gated calcium channel blockers and application for the prevention of inflammation and angiogenesis. J Neuroinflammation. 2020 Apr 25; 17(1):132. PMID: 32334630.
    Citations: 1     Fields:    Translation:AnimalsCells
  13. Balt J, Jamyanjav B, Jav S, Dandii Z, Ganbold C, Horie Y, Lennikov A, Uehara O, Ohno S, Kitaichi N. Clinical features of Behcet's disease in Mongolia: a multicenter study. Clin Rheumatol. 2020 Sep; 39(9):2697-2706. PMID: 32157471.
    Citations:    Fields:    Translation:Humans
  14. Saddala MS, Lennikov A, Huang H. Discovery of Small-Molecule Activators for Glucose-6-Phosphate Dehydrogenase (G6PD) Using Machine Learning Approaches. Int J Mol Sci. 2020 Feb 23; 21(4). PMID: 32102234.
    Citations: 2     Fields:    Translation:HumansAnimalsCells
  15. Saddala MS, Lennikov A, Huang H. Placental growth factor regulates the pentose phosphate pathway and antioxidant defense systems in human retinal endothelial cells. J Proteomics. 2020 04 15; 217:103682. PMID: 32058040.
    Citations: 3     Fields:    Translation:HumansCells
  16. Saddala MS, Lennikov A, Bouras A, Huang H. RNA-Seq reveals differential expression profiles and functional annotation of genes involved in retinal degeneration in Pde6c mutant Danio rerio. BMC Genomics. 2020 Feb 07; 21(1):132. PMID: 32033529.
    Citations: 4     Fields:    Translation:AnimalsCells
  17. Huang H, Lennikov A, Saddala MS, Gozal D, Grab DJ, Khalyfa A, Fan L. Placental growth factor negatively regulates retinal endothelial cell barrier function through suppression of glucose-6-phosphate dehydrogenase and antioxidant defense systems. FASEB J. 2019 12; 33(12):13695-13709. PMID: 31585507.
    Citations: 9     Fields:    Translation:HumansCells
  18. Mukwaya A, Mirabelli P, Lennikov A, Thangavelu M, Ntzouni M, Jensen L, Peebo B, Lagali N. Revascularization after angiogenesis inhibition favors new sprouting over abandoned vessel reuse. Angiogenesis. 2019 11; 22(4):553-567. PMID: 31486010.
    Citations: 6     Fields:    Translation:AnimalsCells
  19. Lennikov A, Saddala MS, Mukwaya A, Tang S, Huang H. Autoimmune-Mediated Retinopathy in CXCR5-Deficient Mice as the Result of Age-Related Macular Degeneration Associated Proteins Accumulation. Front Immunol. 2019; 10:1903. PMID: 31474986.
    Citations: 6     Fields:    Translation:AnimalsCells
  20. Mukwaya A, Mirabelli P, Lennikov A, Thangavelu M, Jensen L, Peebo B, Lagali N. Repeat Corneal Neovascularization is Characterized by More Aggressive Inflammation and Vessel Invasion Than in the Initial Phase. Invest Ophthalmol Vis Sci. 2019 07 01; 60(8):2990-3001. PMID: 31310656.
    Citations: 3     Fields:    Translation:AnimalsCells
  21. Ali Z, Mukwaya A, Biesemeier A, Ntzouni M, Ramsköld D, Giatrellis S, Mammadzada P, Cao R, Lennikov A, Marass M, Gerri C, Hildesjö C, Taylor M, Deng Q, Peebo B, Del Peso L, Kvanta A, Sandberg R, Schraermeyer U, Andre H, Steffensen JF, Lagali N, Cao Y, Kele J, Jensen LD. Intussusceptive Vascular Remodeling Precedes Pathological Neovascularization. Arterioscler Thromb Vasc Biol. 2019 07; 39(7):1402-1418. PMID: 31242036.
    Citations: 6     Fields:    Translation:HumansAnimals
  22. Saddala MS, Lennikov A, Mukwaya A, Fan L, Hu Z, Huang H. Transcriptome-wide analysis of differentially expressed chemokine receptors, SNPs, and SSRs in the age-related macular degeneration. Hum Genomics. 2019 03 20; 13(1):15. PMID: 30894217.
    Citations: 7     Fields:    Translation:HumansCells
  23. Saddala MS, Lennikov A, Grab DJ, Liu GS, Tang S, Huang H. Proteomics reveals ablation of PlGF increases antioxidant and neuroprotective proteins in the diabetic mouse retina. Sci Rep. 2018 11 13; 8(1):16728. PMID: 30425286.
    Citations: 10     Fields:    Translation:Animals
  24. Mukwaya A, Lennikov A, Xeroudaki M, Mirabelli P, Lachota M, Jensen L, Peebo B, Lagali N. Time-dependent LXR/RXR pathway modulation characterizes capillary remodeling in inflammatory corneal neovascularization. Angiogenesis. 2018 05; 21(2):395-413. PMID: 29445990.
    Citations: 11     Fields:    Translation:AnimalsCells
  25. Lennikov A, Mirabelli P, Mukwaya A, Schaupper M, Thangavelu M, Lachota M, Ali Z, Jensen L, Lagali N. Selective IKK2 inhibitor IMD0354 disrupts NF-?B signaling to suppress corneal inflammation and angiogenesis. Angiogenesis. 2018 05; 21(2):267-285. PMID: 29332242.
    Citations: 15     Fields:    Translation:HumansAnimalsCells
  26. Harada F, Morikawa T, Lennikov A, Mukwaya A, Schaupper M, Uehara O, Takai R, Yoshida K, Sato J, Horie Y, Sakaguchi H, Wu CZ, Abiko Y, Lagali N, Kitaichi N. Protective Effects of Oral Astaxanthin Nanopowder against Ultraviolet-Induced Photokeratitis in Mice. Oxid Med Cell Longev. 2017; 2017:1956104. PMID: 29104724.
    Citations: 2     Fields:    Translation:Animals
  27. Mirabelli P, Mukwaya A, Lennikov A, Xeroudaki M, Peebo B, Schaupper M, Lagali N. Genome-wide expression differences in anti-Vegf and dexamethasone treatment of inflammatory angiogenesis in the rat cornea. Sci Rep. 2017 08 15; 7(1):7616. PMID: 28811496.
    Citations: 5     Fields:    Translation:AnimalsCells
  28. Mukwaya A, Mirabelli P, Lennikov A, Xeroudaki M, Schaupper M, Peebo B, Lagali N. Genome-wide expression datasets of anti-VEGF and dexamethasone treatment of angiogenesis in the rat cornea. Sci Data. 2017 08 15; 4:170111. PMID: 28809847.
    Citations: 2     Fields:    Translation:Animals
  29. Mukwaya A, Lindvall JM, Xeroudaki M, Peebo B, Ali Z, Lennikov A, Jensen LD, Lagali N. A microarray whole-genome gene expression dataset in a rat model of inflammatory corneal angiogenesis. Sci Data. 2016 11 22; 3:160103. PMID: 27874850.
    Citations: 5     Fields:    Translation:Animals
  30. Mukwaya A, Peebo B, Xeroudaki M, Ali Z, Lennikov A, Jensen L, Lagali N. Factors regulating capillary remodeling in a reversible model of inflammatory corneal angiogenesis. Sci Rep. 2016 08 26; 6:32137. PMID: 27561355.
    Citations: 13     Fields:    Translation:Animals
  31. Lennikov A, Hiraoka M, Abe A, Ohno S, Fujikawa T, Itai A, Ohguro H. I?B kinase-ß inhibitor IMD-0354 beneficially suppresses retinal vascular permeability in streptozotocin-induced diabetic mice. Invest Ophthalmol Vis Sci. 2014 Sep 09; 55(10):6365-73. PMID: 25205865.
    Citations: 9     Fields:    Translation:Animals
  32. Dong Z, Iwata D, Kitaichi N, Takeuchi M, Sato M, Endo N, Iwabuchi K, Ando R, Fukuhara J, Kinoshita S, Lennikov A, Kitamura M, Mizuuchi K, Kanda A, Noda K, Namba K, Yamagishi S, Ohno S, Ishida S. Amelioration of experimental autoimmune uveoretinitis by inhibition of glyceraldehyde-derived advanced glycation end-product formation. J Leukoc Biol. 2014 Dec; 96(6):1077-85. PMID: 25201803.
    Citations: 5     Fields:    Translation:HumansAnimalsCells
  33. Lennikov A, Kitaichi N, Noda K, Mizuuchi K, Ando R, Dong Z, Fukuhara J, Kinoshita S, Namba K, Ohno S, Ishida S. Amelioration of endotoxin-induced uveitis treated with the sea urchin pigment echinochrome in rats. Mol Vis. 2014; 20:171-7. PMID: 24520186.
    Citations: 15     Fields:    Translation:AnimalsCells
  34. Lennikov A, Alekberova Z, Goloeva R, Kitaichi N, Denisov L, Namba K, Takeno M, Ishigatsubo Y, Mizuki N, Nasonov E, Ishida S, Ohno S. Single center study on ethnic and clinical features of Behcet's disease in Moscow, Russia. Clin Rheumatol. 2015 Feb; 34(2):321-7. PMID: 24322831.
    Citations: 4     Fields:    Translation:Humans
  35. Hiraoka M, Abe A, Lennikov A, Kitaichi N, Ishida S, Ohguro H. Increase of lysosomal phospholipase A2 in aqueous humor by uveitis. Exp Eye Res. 2014 Jan; 118:13-9. PMID: 24161624.
    Citations:    Fields:    Translation:HumansAnimalsCells
  36. Lennikov A, Kitaichi N, Kase S, Noda K, Horie Y, Nakai A, Ohno S, Ishida S. Induction of heat shock protein 70 ameliorates ultraviolet-induced photokeratitis in mice. Int J Mol Sci. 2013 Jan 22; 14(1):2175-89. PMID: 23340653.
    Citations: 7     Fields:    Translation:Animals
  37. Fukuhara J, Noda K, Murata M, Namba S, Kinoshita S, Dong Z, Ando R, Lennikov A, Kanda A, Ishida S. Tissue kallikrein attenuates choroidal neovascularization via cleavage of vascular endothelial growth factor. Invest Ophthalmol Vis Sci. 2013 Jan 09; 54(1):274-9. PMID: 23233257.
    Citations: 5     Fields:    Translation:Animals
  38. Lennikov A, Kitaichi N, Noda K, Ando R, Dong Z, Fukuhara J, Kinoshita S, Namba K, Mizutani M, Fujikawa T, Itai A, Ohno S, Ishida S. Amelioration of endotoxin-induced uveitis treated with an I?B kinase ß inhibitor in rats. Mol Vis. 2012; 18:2586-97. PMID: 23112571.
    Citations: 11     Fields:    Translation:AnimalsCells
  39. Lennikov A, Kitaichi N, Fukase R, Murata M, Noda K, Ando R, Ohguchi T, Kawakita T, Ohno S, Ishida S. Amelioration of ultraviolet-induced photokeratitis in mice treated with astaxanthin eye drops. Mol Vis. 2012; 18:455-64. PMID: 22393271.
    Citations: 14     Fields:    Translation:AnimalsCells
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.