Harvard Catalyst Profiles

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Erik Klontz, M.D.


Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Klontz EH. Chop-Chop: The Future of Bacterial Enzymes in Transfusion Medicine. Transfus Med Rev. 2022 Aug 28. PMID: 36150947.
    Citations:    Fields:    
  2. Trastoy B, Du JJ, García-Alija M, Li C, Klontz EH, Wang LX, Sundberg EJ, Guerin ME. Sculpting therapeutic monoclonal antibody N-glycans using endoglycosidases. Curr Opin Struct Biol. 2022 02; 72:248-259. PMID: 34998123; PMCID: PMC8860878.
    Citations: 1     Fields:    Translation:HumansCells
  3. Fields JK, Kihn K, Birkedal GS, Klontz EH, Sjöström K, Günther S, Beadenkopf R, Forsberg G, Liberg D, Snyder GA, Deredge D, Sundberg EJ. Molecular Basis of Selective Cytokine Signaling Inhibition by Antibodies Targeting a Shared Receptor. Front Immunol. 2021; 12:779100. PMID: 35003094; PMCID: PMC8740070.
    Citations: 2     Fields:    Translation:HumansCells
  4. Aytenfisu AH, Deredge D, Klontz EH, Du J, Sundberg EJ, MacKerell AD. Insights into substrate recognition and specificity for IgG by Endoglycosidase S2. PLoS Comput Biol. 2021 07; 17(7):e1009103. PMID: 34310592; PMCID: PMC8354483.
    Citations: 1     Fields:    Translation:HumansCells
  5. Trastoy B, Du JJ, Li C, García-Alija M, Klontz EH, Roberts BR, Donahue TC, Wang LX, Sundberg EJ, Guerin ME. GH18 endo-ß-N-acetylglucosaminidases use distinct mechanisms to process hybrid-type N-linked glycans. J Biol Chem. 2021 08; 297(2):101011. PMID: 34324829; PMCID: PMC8374693.
    Citations: 1     Fields:    Translation:Cells
  6. Klontz EH, Li C, Kihn K, Fields JK, Beckett D, Snyder GA, Wintrode PL, Deredge D, Wang LX, Sundberg EJ. Structure and dynamics of an a-fucosidase reveal a mechanism for highly efficient IgG transfucosylation. Nat Commun. 2020 12 04; 11(1):6204. PMID: 33277506.
    Citations: 2     Fields:    Translation:HumansCells
  7. Du JJ, Klontz EH, Guerin ME, Trastoy B, Sundberg EJ. Structural insights into the mechanisms and specificities of IgG-active endoglycosidases. Glycobiology. 2020 03 20; 30(4):268-279. PMID: 31172182.
    Citations: 6     Fields:    Translation:HumansAnimalsCells
  8. Trastoy B, Du JJ, Klontz EH, Li C, Cifuente JO, Wang LX, Sundberg EJ, Guerin ME. Structural basis of mammalian high-mannose N-glycan processing by human gut Bacteroides. Nat Commun. 2020 02 14; 11(1):899. PMID: 32060313.
    Citations: 11     Fields:    Translation:HumansCells
  9. Tomich AD, Klontz EH, Deredge D, Barnard JP, McElheny CL, Eshbach ML, Weisz OA, Wintrode P, Doi Y, Sundberg EJ, Sluis-Cremer N. Small-Molecule Inhibitor of FosA Expands Fosfomycin Activity to Multidrug-Resistant Gram-Negative Pathogens. Antimicrob Agents Chemother. 2019 03; 63(3). PMID: 30642934; PMCID: PMC6395921.
    Citations: 7     Fields:    Translation:HumansCells
  10. Klontz EH, Trastoy B, Deredge D, Fields JK, Li C, Orwenyo J, Marina A, Beadenkopf R, Günther S, Flores J, Wintrode PL, Wang LX, Guerin ME, Sundberg EJ. Molecular Basis of Broad Spectrum N-Glycan Specificity and Processing of Therapeutic IgG Monoclonal Antibodies by Endoglycosidase S2. ACS Cent Sci. 2019 Mar 27; 5(3):524-538. PMID: 30937380; PMCID: PMC6439443.
    Citations: 12     
  11. Trastoy B, Klontz E, Orwenyo J, Marina A, Wang LX, Sundberg EJ, Guerin ME. Structural basis for the recognition of complex-type N-glycans by Endoglycosidase S. Nat Commun. 2018 05 14; 9(1):1874. PMID: 29760474.
    Citations: 15     Fields:    Translation:AnimalsCells
  12. Klontz EH, Tomich AD, Günther S, Lemkul JA, Deredge D, Silverstein Z, Shaw JF, McElheny C, Doi Y, Wintrode PL, MacKerell AD, Sluis-Cremer N, Sundberg EJ. Structure and Dynamics of FosA-Mediated Fosfomycin Resistance in Klebsiella pneumoniae and Escherichia coli. Antimicrob Agents Chemother. 2017 11; 61(11). PMID: 28874374; PMCID: PMC5655077.
    Citations: 14     Fields:    Translation:Cells
  13. Klontz EH, Sundberg EJ. Getting oriented with antibodies. Biochem J. 2017 02 15; 474(4):517-519. PMID: 28159897.
    Citations: 1     Fields:    Translation:Cells
  14. Klontz EH, Das SK, Ahmed D, Ahmed S, Chisti MJ, Malek MA, Faruque AS, Klontz KC. Long-term comparison of antibiotic resistance in Vibrio cholerae O1 and Shigella species between urban and rural Bangladesh. Clin Infect Dis. 2014 May; 58(9):e133-6. PMID: 24457344.
    Citations: 10     Fields:    Translation:HumansCells
  15. Das SK, Klontz EH, Azmi IJ, Ud-Din AI, Chisti MJ, Afrad MH, Malek MA, Ahmed S, Das J, Talukder KA, Salam MA, Bardhan PK, Faruque AS, Klontz KC. Characteristics of Multidrug Resistant Shigella and Vibrio cholerae O1 Infections in Patients Treated at an Urban and a Rural Hospital in Bangladesh. ISRN Microbiol. 2013 Dec 22; 2013:213915. PMID: 24455398.
    Citations: 7     
  16. Klontz EH, Faruque AS, Das SK, Malek MA, Islam Z, Luby SP, Klontz KC. Clinical and Epidemiologic Features of Diarrheal Disease due to Aeromonas hydrophila and Plesiomonas shigelloides Infections Compared with Those due to Vibrio cholerae Non-O1 and Vibrio parahaemolyticus in Bangladesh. ISRN Microbiol. 2012; 2012:654819. PMID: 23762755.
    Citations: 6     
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.