Harvard Catalyst Profiles

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Isabel Graupera, Ph.D.

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Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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  1. Goncalves RLS, Wang ZB, Inouye KE, Lee GY, Fu X, Saksi J, Rosique C, Parlakgul G, Arruda AP, Hui ST, Loperena MC, Burgess SC, Graupera I, Hotamisligil GS. Ubiquinone deficiency drives reverse electron transport to disrupt hepatic metabolic homeostasis in obesity. bioRxiv. 2023 Feb 22. PMID: 36865319; PMCID: PMC9980148.
    Citations:    
  2. Carrión JA, Graupera I, Vergara M, Morillas RM, Pericàs JM, Poca M, Amador A, Fernández R, Monllor T, Muñoz L, Bartres MC, Genescà J, Ginés P, Forns X. Position paper of the Catalan Society of Gastroenterology about hepatic elastography 2022. Gastroenterol Hepatol. 2022 Nov 23. PMID: 36435378.
    Citations:    Fields:    
  3. Bassegoda O, Rivera-Esteban J, Serra I, Morillas R, Broquetas T, Vergara M, Rodriguez A, Aracil C, Virolés S, Carrión JA, Pardo A, Rodríguez-Tajes S, Serra-Burriel M, Pericàs JM, Augustin S, Ginès P, Graupera I. High frequency of acute decompensation and cancer in patients with compensated cirrhosis due to nonalcoholic fatty liver disease: A retrospective cohort study. Hepatol Commun. 2022 11; 6(11):3212-3222. PMID: 36073343; PMCID: PMC9592787.
    Citations: 1     Fields:    Translation:Humans
  4. Rivera-Esteban J, Manzano-Nuñez R, Broquetas T, Serra-Matamala I, Bassegoda O, Soriano-Varela A, Espín G, Castillo J, Bañares J, Carrión JA, Ginès P, Graupera I, Pericàs JM. Impact of the COVID-19 pandemic on the care and outcomes of people with NAFLD-related cirrhosis. JHEP Rep. 2022 Nov; 4(11):100574. PMID: 36061511; PMCID: PMC9419430.
    Citations:    
  5. Graupera I, Thiele M, Ma AT, Serra-Burriel M, Pich J, Fabrellas N, Caballeria L, de Knegt RJ, Grgurevic I, Reichert M, Roulot D, Schattenberg JM, Pericas JM, Angeli P, Tsochatzis EA, Guha IN, Garcia-Retortillo M, Morillas RM, Hernández R, Hoyo J, Fuentes M, Madir A, Juanola A, Soria A, Juan M, Carol M, Diaz A, Detlefsen S, Toran P, Fournier C, Llorca A, Newsome PN, Manns M, de Koning HJ, Serra-Burriel F, Cucchietti F, Arslanow A, Korenjak M, van Kleef L, Falcó JL, Kamath PS, Karlsen TH, Castera L, Lammert F, Krag A, Ginès P. LiverScreen project: study protocol for screening for liver fibrosis in the general population in European countries. BMC Public Health. 2022 07 19; 22(1):1385. PMID: 35854275; PMCID: PMC9295430.
    Citations: 3     Fields:    Translation:HumansPHPublic HealthCTClinical Trials
  6. Romero-Gómez M, Aller R, Ampuero J, Fernández Rodríguez C, Augustín S, Latorre R, Rivera-Esteban J, Martínez Urroz B, Gutiérrez García ML, López SA, Albillos A, Hernández M, Graupera I, Benlloch S, Olveira A, Crespo J, Calleja JL. AEEH «Consensus about detection and referral of hidden prevalent liver diseases». Gastroenterol Hepatol. 2023 Mar; 46(3):236-247. PMID: 35569541.
    Citations:    Fields:    
  7. Napoleone L, Solé C, Juanola A, Ma AT, Carol M, Pérez-Guasch M, Rubio AB, Cervera M, Avitabile E, Bassegoda O, Gratacós-Ginès J, Morales-Ruiz M, Fabrellas N, Graupera I, Pose E, Crespo G, Solà E, Ginès P. Patterns of kidney dysfunction in acute-on-chronic liver failure: Relationship with kidney and patients' outcome. Hepatol Commun. 2022 08; 6(8):2121-2131. PMID: 35535681; PMCID: PMC9315130.
    Citations: 2     Fields:    Translation:Humans
  8. Carol M, Pérez-Guasch M, Solà E, Cervera M, Martínez S, Juanola A, Ma AT, Avitabile E, Napoleone L, Pose E, Graupera I, Honrubia M, Korenjak M, Torres F, Ginès P, Fabrellas N. Stigmatization is common in patients with non-alcoholic fatty liver disease and correlates with quality of life. PLoS One. 2022; 17(4):e0265153. PMID: 35385510; PMCID: PMC8986095.
    Citations:    Fields:    Translation:Humans
  9. Graupera I, Isus L, Coll M, Pose E, Díaz A, Vallverdú J, Rubio-Tomás T, Martínez-Sánchez C, Huelin P, Llopis M, Solé C, Fondevila C, Lozano JJ, Sancho-Bru P, Ginès P, Aloy P. Molecular characterization of chronic liver disease dynamics: From liver fibrosis to acute-on-chronic liver failure. JHEP Rep. 2022 Jun; 4(6):100482. PMID: 35540106; PMCID: PMC9079303.
    Citations: 1     
  10. Thiele M, Serra-Burriel M, Graupera I, Krag A. Reply. Clin Gastroenterol Hepatol. 2023 Jan; 21(1):239-240. PMID: 35381383.
    Citations:    Fields:    
  11. Gallego-Durán R, Albillos A, Ampuero J, Arechederra M, Bañares R, Blas-García A, Berná G, Caparrós E, Delgado TC, Falcón-Pérez JM, Francés R, Fernández-Barrena MG, Graupera I, Iruzubieta P, Nevzorova YA, Nogueiras R, Macías RIR, Martín F, Sabio G, Soriano G, Vaquero J, Cubero FJ, Gracia-Sancho J. Metabolic-associated fatty liver disease: From simple steatosis toward liver cirrhosis and potential complications. Proceedings of the Third Translational Hepatology Meeting, organized by the Spanish Association for the Study of the Liver (AEEH). Gastroenterol Hepatol. 2022 Nov; 45(9):724-734. PMID: 35248669.
    Citations:    Fields:    Translation:Humans
  12. Graupera I, Thiele M, Serra-Burriel M, Caballeria L, Roulot D, Wong GL, Fabrellas N, Guha IN, Arslanow A, Expósito C, Hernández R, Aithal GP, Galle PR, Pera G, Wong VW, Lammert F, Ginès P, Castera L, Krag A. Low Accuracy of FIB-4 and NAFLD Fibrosis Scores for Screening for Liver Fibrosis in the Population. Clin Gastroenterol Hepatol. 2022 Nov; 20(11):2567-2576.e6. PMID: 34971806.
    Citations: 20     Fields:    Translation:Humans
  13. Bassegoda O, Olivas P, Graupera I, Hernández-Gea V. Reply. Clin Gastroenterol Hepatol. 2022 Oct; 20(10):2416. PMID: 34971810.
    Citations:    Fields:    
  14. Coll M, Ariño S, Martínez-Sánchez C, Garcia-Pras E, Gallego J, Moles A, Aguilar-Bravo B, Blaya D, Vallverdú J, Rubio-Tomás T, Lozano JJ, Pose E, Graupera I, Fernández-Vidal A, Pol A, Bataller R, Geng JG, Ginès P, Fernandez M, Sancho-Bru P. Ductular reaction promotes intrahepatic angiogenesis through Slit2-Roundabout 1 signaling. Hepatology. 2022 02; 75(2):353-368. PMID: 34490644; PMCID: PMC8766889.
    Citations: 3     Fields:    Translation:HumansAnimalsCells
  15. Ginès P, Castera L, Lammert F, Graupera I, Serra-Burriel M, Allen AM, Wong VW, Hartmann P, Thiele M, Caballeria L, de Knegt RJ, Grgurevic I, Augustin S, Tsochatzis EA, Schattenberg JM, Guha IN, Martini A, Morillas RM, Garcia-Retortillo M, de Koning HJ, Fabrellas N, Pich J, Ma AT, Diaz MA, Roulot D, Newsome PN, Manns M, Kamath PS, Krag A. Population screening for liver fibrosis: Toward early diagnosis and intervention for chronic liver diseases. Hepatology. 2022 01; 75(1):219-228. PMID: 34537988.
    Citations: 27     Fields:    Translation:HumansPHPublic Health
  16. Bassegoda O, Olivas P, Graupera I, Hernández-Gea V. Reply. Clin Gastroenterol Hepatol. 2022 Sep; 20(9):2155. PMID: 34883276.
    Citations:    Fields:    
  17. Taubert R, Engel B, Diestelhorst J, Hupa-Breier KL, Behrendt P, Baerlecken NT, Sühs KW, Janik MK, Zachou K, Sebode M, Schramm C, Londoño MC, Habes S, Oo YH, Lalanne C, Pape S, Schubert M, Hust M, Dübel S, Thevis M, Jonigk D, Beimdiek J, Buettner FFR, Drenth JPH, Muratori L, Adams DH, Dyson JK, Renand A, Graupera I, Lohse AW, Dalekos GN, Milkiewicz P, Stangel M, Maasoumy B, Witte T, Wedemeyer H, Manns MP, Jaeckel E. Quantification of polyreactive immunoglobulin G facilitates the diagnosis of autoimmune hepatitis. Hepatology. 2022 01; 75(1):13-27. PMID: 34473365.
    Citations: 2     Fields:    Translation:Humans
  18. Karlsen TH, Sheron N, Zelber-Sagi S, Carrieri P, Dusheiko G, Bugianesi E, Pryke R, Hutchinson SJ, Sangro B, Martin NK, Cecchini M, Dirac MA, Belloni A, Serra-Burriel M, Ponsioen CY, Sheena B, Lerouge A, Devaux M, Scott N, Hellard M, Verkade HJ, Sturm E, Marchesini G, Yki-Järvinen H, Byrne CD, Targher G, Tur-Sinai A, Barrett D, Ninburg M, Reic T, Taylor A, Rhodes T, Treloar C, Petersen C, Schramm C, Flisiak R, Simonova MY, Pares A, Johnson P, Cucchetti A, Graupera I, Lionis C, Pose E, Fabrellas N, Ma AT, Mendive JM, Mazzaferro V, Rutter H, Cortez-Pinto H, Kelly D, Burton R, Lazarus JV, Ginès P, Buti M, Newsome PN, Burra P, Manns MP. The EASL-Lancet Liver Commission: protecting the next generation of Europeans against liver disease complications and premature mortality. Lancet. 2022 01 01; 399(10319):61-116. PMID: 34863359.
    Citations: 44     Fields:    Translation:Humans
  19. Campreciós G, Ruart M, Anton A, Suárez-Herrera N, Montironi C, Martínez C, Jiménez N, Lafoz E, García-Calderó H, Vilaseca M, Magaz M, Coll M, Graupera I, Friedman SL, García-Pagán JC, Hernández-Gea V. Spermidine Supplementation Protects the Liver Endothelium from Liver Damage in Mice. Nutrients. 2021 Oct 21; 13(11). PMID: 34835956.
    Citations:    Fields:    Translation:AnimalsCells
  20. Bassegoda O, Olivas P, Turco L, Mandorfer M, Serra-Burriel M, Tellez L, Kwanten W, Laroyenne A, Farcau O, Alvarado E, Moga L, Vuille-Lessard E, Fortea JI, Ibañez L, Tosetti G, Vanwolleghem T, Larrue H, Burgos-Santamaría D, Stefanescu H, Paternostro R, Cippitelli A, Lens S, Augustin S, Llop E, Laleman W, Trebicka J, Chang J, Masnou H, Zipprich A, Miceli F, Semmler G, Forns X, Primignani M, Bañares R, Puente A, Berzigotti A, Rautou PE, Villanueva C, Ginès P, Garcia-Pagan JC, Procopet B, Bureau C, Albillos A, Francque S, Reiberger T, Schepis F, Graupera I, Hernandez-Gea V. Decompensation in Advanced Nonalcoholic Fatty Liver Disease May Occur at Lower Hepatic Venous Pressure Gradient Levels Than in Patients With Viral Disease. Clin Gastroenterol Hepatol. 2022 10; 20(10):2276-2286.e6. PMID: 34688952.
    Citations: 7     Fields:    Translation:Humans
  21. Solé C, Ma AT, Solà E, Carol M, Fabrellas N, Juanola A, Napoleone L, Gratacós-Ginès J, Bassegoda O, Cervera M, Pérez M, Rubio AB, Avitabile E, Morales-Ruiz M, Graupera I, Pose E, Kamath PS, Ginès P. Sequential changes in urinary biomarker levels in patients with cirrhosis and severe hepatorenal syndrome. Liver Int. 2021 11; 41(11):2729-2732. PMID: 34569697.
    Citations:    Fields:    Translation:Humans
  22. Osorio-Conles Ó, Vega-Beyhart A, Ibarzabal A, Balibrea JM, Graupera I, Rimola J, Vidal J, de Hollanda A. A Distinctive NAFLD Signature in Adipose Tissue from Women with Severe Obesity. Int J Mol Sci. 2021 Sep 29; 22(19). PMID: 34638880.
    Citations: 4     Fields:    Translation:HumansCTClinical Trials
  23. Juanola A, Graupera I, Elia C, Piano S, Solé C, Carol M, Pérez-Guasch M, Bassegoda O, Escudé L, Rubio AB, Cervera M, Napoleone L, Avitabile E, Ma AT, Fabrellas N, Pose E, Morales-Ruiz M, Jiménez W, Torres F, Crespo G, Solà E, Ginès P. Urinary L-FABP is a promising prognostic biomarker of ACLF and mortality in patients with decompensated cirrhosis. J Hepatol. 2022 01; 76(1):107-114. PMID: 34530063.
    Citations: 2     Fields:    Translation:Humans
  24. Pose E, Coll M, Martínez-Sánchez C, Zeng Z, Surewaard BGJ, Català C, Velasco-de Andrés M, Lozano JJ, Ariño S, Fuster D, Niñerola-Bazán A, Graupera I, Muñoz É, Lozano F, Sancho-Bru P, Kubes P, Ginès P. Programmed Death Ligand 1 Is Overexpressed in Liver Macrophages in Chronic Liver Diseases, and Its Blockade Improves the Antibacterial Activity Against Infections. Hepatology. 2021 07; 74(1):296-311. PMID: 33219516.
    Citations: 7     Fields:    Translation:HumansAnimalsCells
  25. Pose E, Pera G, Torán P, Gratacós-Ginès J, Avitabile E, Expósito C, Díaz A, Graupera I, Rubio AB, Ginès P, Fabrellas N, Caballeria L. Interaction between metabolic syndrome and alcohol consumption, risk factors of liver fibrosis: A population-based study. Liver Int. 2021 07; 41(7):1556-1564. PMID: 33595176.
    Citations: 3     Fields:    Translation:Humans
  26. Blaya D, Pose E, Coll M, Lozano JJ, Graupera I, Schierwagen R, Jansen C, Castro P, Fernandez S, Sidorova J, Vasa-Nicotera M, Solà E, Caballería J, Trebicka J, Ginès P, Sancho-Bru P. Profiling circulating microRNAs in patients with cirrhosis and acute-on-chronic liver failure. JHEP Rep. 2021 Apr; 3(2):100233. PMID: 33665588; PMCID: PMC7902550.
    Citations: 4     
  27. Mezzano G, Juanola A, Cardenas A, Mezey E, Hamilton JP, Pose E, Graupera I, Ginès P, Solà E, Hernaez R. Global burden of disease: acute-on-chronic liver failure, a systematic review and meta-analysis. Gut. 2022 01; 71(1):148-155. PMID: 33436495.
    Citations: 24     Fields:    Translation:Humans
  28. Mezzano G, Cárdenas A, Aguilar F, Pavesi M, Solé C, Napoleone L, Graupera I, Juanola A, Carol M, Pose E, Fabrellas N, Hernaez R, Martínez J, Saliba F, Arroyo V, Sola E, Gines P. Hyperkalemia influences the outcome of patients with cirrhosis with acute decompensation (AD) and acute-on-chronic liver failure (ACLF). Dig Liver Dis. 2021 06; 53(6):738-745. PMID: 33446445.
    Citations: 1     Fields:    Translation:Humans
  29. Ferrusquía-Acosta J, Bassegoda O, Turco L, Reverter E, Pellone M, Bianchini M, Pérez-Campuzano V, Ripoll E, García-Criado Á, Graupera I, García-Pagán JC, Schepis F, Senzolo M, Hernández-Gea V. Agreement between wedged hepatic venous pressure and portal pressure in non-alcoholic steatohepatitis-related cirrhosis. J Hepatol. 2021 04; 74(4):811-818. PMID: 33068638.
    Citations: 10     Fields:    Translation:Humans
  30. Solé C, Guilly S, Da Silva K, Llopis M, Le-Chatelier E, Huelin P, Carol M, Moreira R, Fabrellas N, De Prada G, Napoleone L, Graupera I, Pose E, Juanola A, Borruel N, Berland M, Toapanta D, Casellas F, Guarner F, Doré J, Solà E, Ehrlich SD, Ginès P. Alterations in Gut Microbiome in Cirrhosis as Assessed by Quantitative Metagenomics: Relationship With Acute-on-Chronic Liver Failure and Prognosis. Gastroenterology. 2021 01; 160(1):206-218.e13. PMID: 32941879.
    Citations: 30     Fields:    Translation:Humans
  31. Grønbaek H, Møller HJ, Saliba F, Zeuzem S, Albillos A, Ariza X, Graupera I, Solà E, Amoros A, Pavesi M, Bossen L, Jalan R, Gines P, Arroyo V. Improved prediction of mortality by combinations of inflammatory markers and standard clinical scores in patients with acute-on-chronic liver failure and acute decompensation. J Gastroenterol Hepatol. 2021 Jan; 36(1):240-248. PMID: 32478437.
    Citations: 6     Fields:    Translation:Humans
  32. Ardevol A, Alvarado-Tapias E, Garcia-Guix M, Brujats A, Gonzalez L, Hernández-Gea V, Aracil C, Pavel O, Cuyas B, Graupera I, Colomo A, Poca M, Torras X, Concepción M, Villanueva C. Early rebleeding increases mortality of variecal bleeders on secondary prophylaxis with ß-blockers and ligation. Dig Liver Dis. 2020 09; 52(9):1017-1025. PMID: 32653417.
    Citations: 2     Fields:    Translation:HumansPHPublic Health
  33. Alvarado-Tapias E, Ardevol A, Garcia-Guix M, Montañés R, Pavel O, Cuyas B, Graupera I, Brujats A, Vilades D, Colomo A, Poca M, Torras X, Guarner C, Concepción M, Aracil C, Torres F, Villanueva C. Short-term hemodynamic effects of ß-blockers influence survival of patients with decompensated cirrhosis. J Hepatol. 2020 10; 73(4):829-841. PMID: 32298768.
    Citations: 5     Fields:    Translation:Humans
  34. Fabrellas N, Moreira R, Carol M, Cervera M, de Prada G, Perez M, Vazquez E, Sola M, Sancho R, Juanola A, Pose E, Solé C, Graupera I, Solà E, Kamath PS, Ginès P. Psychological Burden of Hepatic Encephalopathy on Patients and Caregivers. Clin Transl Gastroenterol. 2020 04; 11(4):e00159. PMID: 32352686; PMCID: PMC7263656.
    Citations: 12     Fields:    Translation:Humans
  35. Bassegoda O, Huelin P, Ariza X, Solé C, Juanola A, Gratacós-Ginès J, Carol M, Graupera I, Pose E, Napoleone L, Albertos S, de Prada G, Cervera M, Fernández J, Fabrellas N, Poch E, Solà E, Ginès P. Development of chronic kidney disease after acute kidney injury in patients with cirrhosis is common and impairs clinical outcomes. J Hepatol. 2020 06; 72(6):1132-1139. PMID: 31953138.
    Citations: 16     Fields:    Translation:Humans
  36. Younossi ZM, Ratziu V, Loomba R, Rinella M, Anstee QM, Goodman Z, Bedossa P, Geier A, Beckebaum S, Newsome PN, Sheridan D, Sheikh MY, Trotter J, Knapple W, Lawitz E, Abdelmalek MF, Kowdley KV, Montano-Loza AJ, Boursier J, Mathurin P, Bugianesi E, Mazzella G, Olveira A, Cortez-Pinto H, Graupera I, Orr D, Gluud LL, Dufour JF, Shapiro D, Campagna J, Zaru L, MacConell L, Shringarpure R, Harrison S, Sanyal AJ. Obeticholic acid for the treatment of non-alcoholic steatohepatitis: interim analysis from a multicentre, randomised, placebo-controlled phase 3 trial. Lancet. 2019 12 14; 394(10215):2184-2196. PMID: 31813633.
    Citations: 333     Fields:    Translation:HumansCTClinical Trials
  37. Tutusaus A, de Gregorio E, Cucarull B, Cristóbal H, Aresté C, Graupera I, Coll M, Colell A, Gausdal G, Lorens JB, García de Frutos P, Morales A, Marí M. A Functional Role of GAS6/TAM in Nonalcoholic Steatohepatitis Progression Implicates AXL as Therapeutic Target. Cell Mol Gastroenterol Hepatol. 2020; 9(3):349-368. PMID: 31689560.
    Citations: 22     Fields:    Translation:HumansAnimalsCells
  38. Abu Dayyeh BK, Bazerbachi F, Graupera I, Cardenas A. Endoscopic bariatric and metabolic therapies for non-alcoholic fatty liver disease. J Hepatol. 2019 12; 71(6):1246-1248. PMID: 31570275.
    Citations: 8     Fields:    Translation:HumansCells
  39. Serra-Burriel M, Graupera I, Torán P, Thiele M, Roulot D, Wai-Sun Wong V, Neil Guha I, Fabrellas N, Arslanow A, Expósito C, Hernández R, Lai-Hung Wong G, Harman D, Darwish Murad S, Krag A, Pera G, Angeli P, Galle P, Aithal GP, Caballeria L, Castera L, Ginès P, Lammert F. Transient elastography for screening of liver fibrosis: Cost-effectiveness analysis from six prospective cohorts in Europe and Asia. J Hepatol. 2019 12; 71(6):1141-1151. PMID: 31470067.
    Citations: 39     Fields:    Translation:HumansPHPublic Health
  40. Caballeria L, Augustin S, Broquetas T, Morillas RM, Vergara M, Virolés S, Hernández MR, Serra I, Goday A, Vila L, Siso-Almirall A, Solans R, Fernández-Real JM, Carrión JA, Graupera I, Ginès P. Recommendations for the detection, diagnosis and follow-up of patients with non-alcoholic fatty liver disease in primary and hospital care. Med Clin (Barc). 2019 08 16; 153(4):169-177. PMID: 31178295.
    Citations: 6     Fields:    Translation:Humans
  41. Huelin P, Solà E, Elia C, Solé C, Risso A, Moreira R, Carol M, Fabrellas N, Bassegoda O, Juanola A, de Prada G, Albertos S, Piano S, Graupera I, Ariza X, Napoleone L, Pose E, Filella X, Morales-Ruiz M, Rios J, Fernández J, Jiménez W, Poch E, Torres F, Ginès P. Neutrophil Gelatinase-Associated Lipocalin for Assessment of Acute Kidney Injury in Cirrhosis: A Prospective Study. Hepatology. 2019 07; 70(1):319-333. PMID: 30810244.
    Citations: 24     Fields:    Translation:Humans
  42. Aguilar-Bravo B, Rodrigo-Torres D, Ariño S, Coll M, Pose E, Blaya D, Graupera I, Perea L, Vallverdú J, Rubio-Tomás T, Dubuquoy L, Armengol C, Lo Nigro A, Stärkel P, Mathurin P, Bataller R, Caballería J, José Lozano J, Ginès P, Sancho-Bru P. Ductular Reaction Cells Display an Inflammatory Profile and Recruit Neutrophils in Alcoholic Hepatitis. Hepatology. 2019 05; 69(5):2180-2195. PMID: 30565271; PMCID: PMC9189898.
    Citations: 16     Fields:    Translation:HumansCells
  43. Solé C, Solà E, Huelin P, Carol M, Moreira R, Cereijo U, Mas JM, Graupera I, Pose E, Napoleone L, dePrada G, Juanola A, Fabrellas N, Torres F, Morales-Ruiz M, Farrés J, Jiménez W, Ginès P. Characterization of inflammatory response in hepatorenal syndrome: Relationship with kidney outcome and survival. Liver Int. 2019 07; 39(7):1246-1255. PMID: 30597709.
    Citations: 22     Fields:    Translation:Humans
  44. Fabrellas N, Hernández R, Graupera I, Solà E, Ramos P, Martín N, Sáez G, Simón C, Pérez A, Graell T, Larrañaga A, Garcia M, de la Arada A, Juanola A, Coiduras A, Duaso I, Casado A, Martin J, Ginès M, Moreno N, Gema Perez A, Marti L, Bernat M, Sola M, Olivé C, Solé C, Ginès P. Prevalence of hepatic steatosis as assessed by controlled attenuation parameter (CAP) in subjects with metabolic risk factors in primary care. A population-based study. PLoS One. 2018; 13(9):e0200656. PMID: 30226889.
    Citations: 6     Fields:    Translation:Humans
  45. Solà E, Solé C, Simón-Talero M, Martín-Llahí M, Castellote J, Garcia-Martínez R, Moreira R, Torrens M, Márquez F, Fabrellas N, de Prada G, Huelin P, Lopez Benaiges E, Ventura M, Manríquez M, Nazar A, Ariza X, Suñé P, Graupera I, Pose E, Colmenero J, Pavesi M, Guevara M, Navasa M, Xiol X, Córdoba J, Vargas V, Ginès P. Midodrine and albumin for prevention of complications in patients with cirrhosis awaiting liver transplantation. A randomized placebo-controlled trial. J Hepatol. 2018 12; 69(6):1250-1259. PMID: 30138685.
    Citations: 44     Fields:    Translation:Humans
  46. Graupera I, Lammert F. Screening is caring: Community-based non-invasive diagnosis and treatment strategies for hepatitis C to reduce liver disease burden. J Hepatol. 2018 09; 69(3):562-563. PMID: 29983202.
    Citations:    Fields:    Translation:HumansCells
  47. Coll M, Perea L, Boon R, Leite SB, Vallverdú J, Mannaerts I, Smout A, El Taghdouini A, Blaya D, Rodrigo-Torres D, Graupera I, Aguilar-Bravo B, Chesne C, Najimi M, Sokal E, Lozano JJ, van Grunsven LA, Verfaillie CM, Sancho-Bru P. Generation of Hepatic Stellate Cells from Human Pluripotent Stem Cells Enables In Vitro Modeling of Liver Fibrosis. Cell Stem Cell. 2018 Jul 05; 23(1):101-113.e7. PMID: 30049452.
    Citations: 66     Fields:    Translation:HumansCells
  48. Blaya D, Aguilar-Bravo B, Hao F, Casacuberta-Serra S, Coll M, Perea L, Vallverdú J, Graupera I, Pose E, Llovet L, Barquinero J, Cubero FJ, Caballería J, Ginès P, Sancho-Bru P. Expression of microRNA-155 in inflammatory cells modulates liver injury. Hepatology. 2018 08; 68(2):691-706. PMID: 29420849.
    Citations: 25     Fields:    Translation:HumansAnimalsCells
  49. Caballería L, Pera G, Arteaga I, Rodríguez L, Alumà A, Morillas RM, de la Ossa N, Díaz A, Expósito C, Miranda D, Sánchez C, Prats RM, Urquizu M, Salgado A, Alemany M, Martinez A, Majeed I, Fabrellas N, Graupera I, Planas R, Ojanguren I, Serra M, Torán P, Caballería J, Ginès P. High Prevalence of Liver Fibrosis Among European Adults With Unknown Liver Disease: A Population-Based Study. Clin Gastroenterol Hepatol. 2018 07; 16(7):1138-1145.e5. PMID: 29452268.
    Citations: 67     Fields:    Translation:Humans
  50. Villanueva C, Graupera I, Alvarado E. Reply. Hepatology. 2017 10; 66(4):1363-1364. PMID: 28741289.
    Citations: 1     Fields:    
  51. Augustin S, Graupera I, Caballeria J. Non-alcoholic fatty liver disease: A poorly known pandemic. Med Clin (Barc). 2017 Dec 20; 149(12):542-548. PMID: 28751080.
    Citations: 8     Fields:    Translation:HumansPHPublic Health
  52. Perea L, Coll M, Sanjurjo L, Blaya D, Taghdouini AE, Rodrigo-Torres D, Altamirano J, Graupera I, Aguilar-Bravo B, Llopis M, Vallverdú J, Caballeria J, van Grunsven LA, Sarrias MR, Ginès P, Sancho-Bru P. Pentraxin-3 modulates lipopolysaccharide-induced inflammatory response and attenuates liver injury. Hepatology. 2017 09; 66(3):953-968. PMID: 28422322.
    Citations: 21     Fields:    Translation:HumansAnimalsCells
  53. Graupera I, Coll M, Pose E, Elia C, Piano S, Solà E, Blaya D, Huelin P, Solé C, Moreira R, de Prada G, Fabrellas N, Juanola A, Morales-Ruiz M, Sancho-Bru P, Villanueva C, Ginès P. Adipocyte Fatty-Acid Binding Protein is Overexpressed in Cirrhosis and Correlates with Clinical Outcomes. Sci Rep. 2017 05 12; 7(1):1829. PMID: 28500294.
    Citations: 14     Fields:    Translation:HumansCells
  54. Villanueva C, Graupera I, Aracil C, Alvarado E, Miñana J, Puente Á, Hernandez-Gea V, Ardevol A, Pavel O, Colomo A, Concepción M, Poca M, Torras X, Reñe JM, Guarner C. A randomized trial to assess whether portal pressure guided therapy to prevent variceal rebleeding improves survival in cirrhosis. Hepatology. 2017 May; 65(5):1693-1707. PMID: 28100019.
    Citations: 22     Fields:    Translation:Humans
  55. Ginès P, Graupera I, Lammert F, Angeli P, Caballeria L, Krag A, Guha IN, Murad SD, Castera L. Screening studies of transient elastography and FibroTest in the general population - Authors' reply. Lancet Gastroenterol Hepatol. 2017 04; 2(4):246-247. PMID: 28404149.
    Citations:    Fields:    Translation:Humans
  56. Puthumana J, Ariza X, Belcher JM, Graupera I, Ginès P, Parikh CR. Urine Interleukin 18 and Lipocalin 2 Are Biomarkers of Acute Tubular Necrosis in Patients With Cirrhosis: A Systematic Review and Meta-analysis. Clin Gastroenterol Hepatol. 2017 Jul; 15(7):1003-1013.e3. PMID: 28013112.
    Citations: 21     Fields:    Translation:Humans
  57. Pose E, Solà E, Piano S, Gola E, Graupera I, Guevara M, Cárdenas A, Angeli P, Ginès P. Limited Efficacy of Tolvaptan in Patients with Cirrhosis and Severe Hyponatremia: Real-Life Experience. Am J Med. 2017 Mar; 130(3):372-375. PMID: 27746291.
    Citations: 13     Fields:    Translation:HumansCTClinical Trials
  58. Ginès P, Graupera I, Lammert F, Angeli P, Caballeria L, Krag A, Guha IN, Murad SD, Castera L. Screening for liver fibrosis in the general population: a call for action. Lancet Gastroenterol Hepatol. 2016 11; 1(3):256-260. PMID: 28404098.
    Citations: 42     Fields:    Translation:HumansPHPublic Health
  59. Huelin P, Piano S, Solà E, Stanco M, Solé C, Moreira R, Pose E, Fasolato S, Fabrellas N, de Prada G, Pilutti C, Graupera I, Ariza X, Romano A, Elia C, Cárdenas A, Fernández J, Angeli P, Ginès P. Validation of a Staging System for Acute Kidney Injury in Patients With Cirrhosis and Association With Acute-on-Chronic Liver Failure. Clin Gastroenterol Hepatol. 2017 03; 15(3):438-445.e5. PMID: 27720915.
    Citations: 31     Fields:    Translation:Humans
  60. Solé C, Solà E, Morales-Ruiz M, Fernàndez G, Huelin P, Graupera I, Moreira R, de Prada G, Ariza X, Pose E, Fabrellas N, Kalko SG, Jiménez W, Ginès P. Characterization of Inflammatory Response in Acute-on-Chronic Liver Failure and Relationship with Prognosis. Sci Rep. 2016 08 31; 6:32341. PMID: 27578545.
    Citations: 39     Fields:    Translation:Humans
  61. Solà E, Kerbert AJ, Verspaget HW, Moreira R, Pose E, Ruiz P, Cela R, Morales-Ruiz M, López E, Graupera I, Solé C, Huelin P, Navarro AA, Ariza X, Jalan R, Fabrellas N, Benten D, de Prada G, Durand F, Jimenez W, van der Reijden JJ, Fernandez J, van Hoek B, Coenraad MJ, Ginès P. Plasma copeptin as biomarker of disease progression and prognosis in cirrhosis. J Hepatol. 2016 11; 65(5):914-920. PMID: 27422752.
    Citations: 10     Fields:    Translation:Humans
  62. Graupera I, Solà E, Fabrellas N, Moreira R, Solé C, Huelin P, de la Prada G, Pose E, Ariza X, Risso A, Albertos S, Morales-Ruiz M, Jiménez W, Ginès P. Urine Monocyte Chemoattractant Protein-1 Is an Independent Predictive Factor of Hospital Readmission and Survival in Cirrhosis. PLoS One. 2016; 11(6):e0157371. PMID: 27359339.
    Citations: 13     Fields:    Translation:Humans
  63. Blaya D, Coll M, Rodrigo-Torres D, Vila-Casadesús M, Altamirano J, Llopis M, Graupera I, Perea L, Aguilar-Bravo B, Díaz A, Banales JM, Clària J, Lozano JJ, Bataller R, Caballería J, Ginès P, Sancho-Bru P. Integrative microRNA profiling in alcoholic hepatitis reveals a role for microRNA-182 in liver injury and inflammation. Gut. 2016 09; 65(9):1535-45. PMID: 27196584.
    Citations: 45     Fields:    Translation:HumansAnimals
  64. Durand F, Graupera I, Ginès P, Olson JC, Nadim MK. Pathogenesis of Hepatorenal Syndrome: Implications for Therapy. Am J Kidney Dis. 2016 Feb; 67(2):318-28. PMID: 26500178.
    Citations: 20     Fields:    Translation:Humans
  65. Coll M, El Taghdouini A, Perea L, Mannaerts I, Vila-Casadesús M, Blaya D, Rodrigo-Torres D, Affò S, Morales-Ibanez O, Graupera I, Lozano JJ, Najimi M, Sokal E, Lambrecht J, Ginès P, van Grunsven LA, Sancho-Bru P. Integrative miRNA and Gene Expression Profiling Analysis of Human Quiescent Hepatic Stellate Cells. Sci Rep. 2015 Jun 22; 5:11549. PMID: 26096707.
    Citations: 47     Fields:    Translation:HumansAnimalsCells
  66. Ariza X, Solà E, Elia C, Barreto R, Moreira R, Morales-Ruiz M, Graupera I, Rodríguez E, Huelin P, Solé C, Fernández J, Jiménez W, Arroyo V, Ginès P. Analysis of a urinary biomarker panel for clinical outcomes assessment in cirrhosis. PLoS One. 2015; 10(6):e0128145. PMID: 26042740.
    Citations: 22     Fields:    Translation:Humans
  67. Graupera I, Ginès P. Hepatorenal syndrome: The last pieces of the puzzle or not yet? Hepatology. 2015 Aug; 62(2):352-4. PMID: 25846649.
    Citations:    Fields:    Translation:Humans
  68. Elia C, Graupera I, Barreto R, Solà E, Moreira R, Huelin P, Ariza X, Solé C, Pose E, Baiges A, Fabrellas N, Poch E, Fernández J, Arroyo V, Ginès P. Severe acute kidney injury associated with non-steroidal anti-inflammatory drugs in cirrhosis: A case-control study. J Hepatol. 2015 Sep; 63(3):593-600. PMID: 25872166.
    Citations: 15     Fields:    Translation:Humans
  69. Graupera I, Pavel O, Hernandez-Gea V, Ardevol A, Webb S, Urgell E, Colomo A, Llaó J, Concepción M, Villanueva C. Relative adrenal insufficiency in severe acute variceal and non-variceal bleeding: influence on outcomes. Liver Int. 2015 Aug; 35(8):1964-73. PMID: 25644679.
    Citations: 2     Fields:    Translation:Humans
  70. Cárdenas A, Solà E, Rodríguez E, Barreto R, Graupera I, Pavesi M, Saliba F, Welzel TM, Martinez-Gonzalez J, Gustot T, Bernardi M, Arroyo V, Ginès P. Hyponatremia influences the outcome of patients with acute-on-chronic liver failure: an analysis of the CANONIC study. Crit Care. 2014 Dec 13; 18(6):700. PMID: 25643318.
    Citations: 15     Fields:    Translation:Humans
  71. Fagundes C, Barreto R, Rodríguez E, Graupera I, Poch E, Solà E, Fernández J, Ginès P. Reply to: "A cut-off serum creatinine value of 1.5 mg/dl for AKI--to be or not to be". J Hepatol. 2015 Mar; 62(3):743-4. PMID: 25485797.
    Citations: 2     Fields:    Translation:Humans
  72. Barreto R, Elia C, Solà E, Moreira R, Ariza X, Rodríguez E, Graupera I, Alfaro I, Morales-Ruiz M, Poch E, Guevara M, Fernández J, Jiménez W, Arroyo V, Ginès P. Urinary neutrophil gelatinase-associated lipocalin predicts kidney outcome and death in patients with cirrhosis and bacterial infections. J Hepatol. 2014 Jul; 61(1):35-42. PMID: 24613364.
    Citations: 41     Fields:    Translation:Humans
  73. Barreto R, Fagundes C, Guevara M, Solà E, Pereira G, Rodríguez E, Graupera I, Martín-Llahí M, Ariza X, Cárdenas A, Fernández J, Rodés J, Arroyo V, Ginès P. Type-1 hepatorenal syndrome associated with infections in cirrhosis: natural history, outcome of kidney function, and survival. Hepatology. 2014 Apr; 59(4):1505-13. PMID: 24037970.
    Citations: 27     Fields:    Translation:Humans
  74. Puente A, Hernández-Gea V, Graupera I, Roque M, Colomo A, Poca M, Aracil C, Gich I, Guarner C, Villanueva C. Drugs plus ligation to prevent rebleeding in cirrhosis: an updated systematic review. Liver Int. 2014 Jul; 34(6):823-33. PMID: 24373180.
    Citations: 30     Fields:    Translation:HumansAnimals
  75. Rodríguez E, Elia C, Solà E, Barreto R, Graupera I, Andrealli A, Pereira G, Poca M, Sánchez J, Guevara M, Soriano G, Alessandria C, Fernández J, Arroyo V, Ginès P. Terlipressin and albumin for type-1 hepatorenal syndrome associated with sepsis. J Hepatol. 2014 May; 60(5):955-61. PMID: 24447876.
    Citations: 31     Fields:    Translation:Humans
  76. Ripoll C, Genescà J, Araujo IK, Graupera I, Augustin S, Tejedor M, Cirera I, Aracil C, Sala M, Hernandez-Guerra M, Llop E, Escorsell A, Catalina MV, Cañete N, Albillos A, Villanueva C, Abraldes JG, Bañares R, Bosch J. Rebleeding prophylaxis improves outcomes in patients with hepatocellular carcinoma. A multicenter case-control study. Hepatology. 2013 Dec; 58(6):2079-88. PMID: 23908019.
    Citations: 12     Fields:    Translation:Humans
  77. Graupera I, Cardenas A. Diagnostic approach to renal failure in cirrhosis. Clin Liver Dis (Hoboken). 2013 Jun; 2(3):128-131. PMID: 30992844; PMCID: PMC6448636.
    Citations: 1     
  78. Fagundes C, Barreto R, Guevara M, Garcia E, Solà E, Rodríguez E, Graupera I, Ariza X, Pereira G, Alfaro I, Cárdenas A, Fernández J, Poch E, Ginès P. A modified acute kidney injury classification for diagnosis and risk stratification of impairment of kidney function in cirrhosis. J Hepatol. 2013 Sep; 59(3):474-81. PMID: 23669284.
    Citations: 77     Fields:    Translation:Humans
  79. Villanueva C, Colomo A, Bosch A, Concepción M, Hernandez-Gea V, Aracil C, Graupera I, Poca M, Alvarez-Urturi C, Gordillo J, Guarner-Argente C, Santaló M, Muñiz E, Guarner C. Transfusion strategies for acute upper gastrointestinal bleeding. N Engl J Med. 2013 Jan 03; 368(1):11-21. PMID: 23281973.
    Citations: 351     Fields:    Translation:Humans
  80. Solà E, Watson H, Graupera I, Turón F, Barreto R, Rodríguez E, Pavesi M, Arroyo V, Guevara M, Ginès P. Factors related to quality of life in patients with cirrhosis and ascites: relevance of serum sodium concentration and leg edema. J Hepatol. 2012 Dec; 57(6):1199-206. PMID: 22824819.
    Citations: 43     Fields:    Translation:Humans
  81. Poca M, Puente A, Graupera I, Villanueva C. Prognostic markers in patients with cirrhosis and portal hypertension who have not bled. Dis Markers. 2011; 31(3):147-54. PMID: 22045400.
    Citations: 7     Fields:    Translation:Humans
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.