Harvard Catalyst Profiles

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Prashanth Rajarajan, M.D.


Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Chandrasekaran S, Espeso-Gil S, Loh YE, Javidfar B, Kassim B, Zhu Y, Zhang Y, Dong Y, Bicks LK, Li H, Rajarajan P, Peter CJ, Sun D, Agullo-Pascual E, Iskhakova M, Estill M, Lesch BJ, Shen L, Jiang Y, Akbarian S. Neuron-specific chromosomal megadomain organization is adaptive to recent retrotransposon expansions. Nat Commun. 2021 12 13; 12(1):7243. PMID: 34903713.
    Citations:    Fields:    Translation:AnimalsCells
  2. Ellis RJ, Bara A, Vargas CA, Frick AL, Loh E, Landry J, Uzamere TO, Callens JE, Martin Q, Rajarajan P, Brennand K, Ramakrishnan A, Shen L, Szutorisz H, Hurd YL. Prenatal ?9-Tetrahydrocannabinol Exposure in Males Leads to Motivational Disturbances Related to Striatal Epigenetic Dysregulation. Biol Psychiatry. 2021 Sep 27. PMID: 34895699.
    Citations:    Fields:    
  3. Sey NYA, Hu B, Mah W, Fauni H, McAfee JC, Rajarajan P, Brennand KJ, Akbarian S, Won H. A computational tool (H-MAGMA) for improved prediction of brain-disorder risk genes by incorporating brain chromatin interaction profiles. Nat Neurosci. 2020 04; 23(4):583-593. PMID: 32152537.
    Citations: 53     Fields:    Translation:HumansCells
  4. Espeso-Gil S, Halene T, Bendl J, Kassim B, Ben Hutta G, Iskhakova M, Shokrian N, Auluck P, Javidfar B, Rajarajan P, Chandrasekaran S, Peter CJ, Cote A, Birnbaum R, Liao W, Borrman T, Wiseman J, Bell A, Bannon MJ, Roussos P, Crary JF, Weng Z, Marenco S, Lipska B, Tsankova NM, Huckins L, Jiang Y, Akbarian S. A chromosomal connectome for psychiatric and metabolic risk variants in adult dopaminergic neurons. Genome Med. 2020 02 19; 12(1):19. PMID: 32075678.
    Citations: 11     Fields:    Translation:HumansAnimalsCells
  5. Rajarajan P, Akbarian S. Use of the epigenetic toolbox?to contextualize common variants associated with schizophrenia risk?. Dialogues Clin Neurosci. 2019 12; 21(4):407-416. PMID: 31949408.
    Citations: 1     Fields:    Translation:HumansCells
  6. Rajarajan P, Flaherty E, Akbarian S, Brennand KJ. CRISPR-based functional evaluation of schizophrenia risk variants. Schizophr Res. 2020 03; 217:26-36. PMID: 31277978.
    Citations: 2     Fields:    Translation:HumansCells
  7. Rajarajan P, Borrman T, Liao W, Espeso-Gil S, Chandrasekaran S, Jiang Y, Weng Z, Brennand KJ, Akbarian S. Spatial genome exploration in the context of cognitive and neurological disease. Curr Opin Neurobiol. 2019 12; 59:112-119. PMID: 31255842.
    Citations: 7     Fields:    Translation:HumansAnimalsCells
  8. Rajarajan P, Borrman T, Liao W, Schrode N, Flaherty E, Casiño C, Powell S, Yashaswini C, LaMarca EA, Kassim B, Javidfar B, Espeso-Gil S, Li A, Won H, Geschwind DH, Ho SM, MacDonald M, Hoffman GE, Roussos P, Zhang B, Hahn CG, Weng Z, Brennand KJ, Akbarian S. Neuron-specific signatures in the chromosomal connectome associated with schizophrenia risk. Science. 2018 12 14; 362(6420). PMID: 30545851.
    Citations: 61     Fields:    Translation:HumansCells
  9. Boks MP, Houtepen LC, Xu Z, He Y, Ursini G, Maihofer AX, Rajarajan P, Yu Q, Xu H, Wu Y, Wang S, Shi JP, Hulshoff Pol HE, Strengman E, Rutten BPF, Jaffe AE, Kleinman JE, Baker DG, Hol EM, Akbarian S, Nievergelt CM, De Witte LD, Vinkers CH, Weinberger DR, Yu J, Kahn RS. Genetic vulnerability to DUSP22 promoter hypermethylation is involved in the relation between in utero famine exposure and schizophrenia. NPJ Schizophr. 2018 Aug 21; 4(1):16. PMID: 30131491.
    Citations: 10     
  10. Rajarajan P, Jiang Y, Kassim BS, Akbarian S. Chromosomal Conformations and Epigenomic Regulation in Schizophrenia. Prog Mol Biol Transl Sci. 2018; 157:21-40. PMID: 29933951.
    Citations: 5     Fields:    Translation:HumansAnimalsCells
  11. Ho SM, Hartley BJ, Flaherty E, Rajarajan P, Abdelaal R, Obiorah I, Barretto N, Muhammad H, Phatnani HP, Akbarian S, Brennand KJ. Evaluating Synthetic Activation and Repression of Neuropsychiatric-Related Genes in hiPSC-Derived NPCs, Neurons, and Astrocytes. Stem Cell Reports. 2017 08 08; 9(2):615-628. PMID: 28757163.
    Citations: 27     Fields:    Translation:HumansCells
  12. Jiang Y, Loh YE, Rajarajan P, Hirayama T, Liao W, Kassim BS, Javidfar B, Hartley BJ, Kleofas L, Park RB, Labonte B, Ho SM, Chandrasekaran S, Do C, Ramirez BR, Peter CJ, C W JT, Safaie BM, Morishita H, Roussos P, Nestler EJ, Schaefer A, Tycko B, Brennand KJ, Yagi T, Shen L, Akbarian S. The methyltransferase SETDB1 regulates a large neuron-specific topological chromatin domain. Nat Genet. 2017 Aug; 49(8):1239-1250. PMID: 28671686.
    Citations: 54     Fields:    Translation:HumansAnimalsCells
  13. Rajarajan P, Gil SE, Brennand KJ, Akbarian S. Spatial genome organization and cognition. Nat Rev Neurosci. 2016 11; 17(11):681-691. PMID: 27708356.
    Citations: 39     Fields:    Translation:HumansAnimalsCells
  14. Diaz JE, Ekasumara N, Menon NR, Homan E, Rajarajan P, Zamudio AR, Kim AJ, Gruener J, Poliandro E, Thomas DC, Meah YS, Soriano RP. Interpreter training for medical students: pilot implementation and assessment in a student-run clinic. BMC Med Educ. 2016 Sep 29; 16(1):256. PMID: 27687285.
    Citations: 3     Fields:    
  15. Topol A, English JA, Flaherty E, Rajarajan P, Hartley BJ, Gupta S, Desland F, Zhu S, Goff T, Friedman L, Rapoport J, Felsenfeld D, Cagney G, Mackay-Sim A, Savas JN, Aronow B, Fang G, Zhang B, Cotter D, Brennand KJ. Increased abundance of translation machinery in stem cell-derived neural progenitor cells from four schizophrenia patients. Transl Psychiatry. 2015 Oct 20; 5:e662. PMID: 26485546.
    Citations: 20     Fields:    Translation:HumansCells
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.