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Gary Steven Sachs, M.D.

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Research
The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
  1. N01MH080001 Sep 30, 1998 - Sep 30, 2003
    NIH/NIMH
    TREATMENT OF BIPOLAR DISORDER-278980001
    Role: Co-Principal Investigator
  2. N01MH060011 (SACHS, GARY S) Sep 30, 1996 - Sep 30, 1999
    NIH/NIMH
    PILOT STUDY OF A CALCIUM CHANNEL BLOCKER IN FEMALES
    Role: Principal Investigator

Bibliographic
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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  1. Rosenblat JD, Simon GE, Sachs GS, Deetz I, Doederlein A, DePeralta D, Dean MM, McIntyre RS. Frequency of use and perceived helpfulness of wellness strategies for bipolar and unipolar depression. Ann Clin Psychiatry. 2018 Nov; 30(4):296-304. PMID: 30372507.
    View in: PubMed
  2. Rosenblat JD, Simon GE, Sachs GS, Deetz I, Doederlein A, DePeralta D, Dean MM, McIntyre RS. Factors That Impact Treatment Decisions: Results From an Online Survey of Individuals With Bipolar and Unipolar Depression. Prim Care Companion CNS Disord. 2018 Nov 01; 20(6). PMID: 30444959.
    View in: PubMed
  3. Rosenblat JD, Simon GE, Sachs GS, Deetz I, Doederlein A, DePeralta D, Dean MM, McIntyre RS. Treatment effectiveness and tolerability outcomes that are most important to individuals with bipolar and unipolar depression. J Affect Disord. 2019 01 15; 243:116-120. PMID: 30241026.
    View in: PubMed
  4. Slyepchenko A, Frey BN, Lafer B, Nierenberg AA, Sachs GS, Dias RS. Increased illness burden in women with comorbid bipolar and premenstrual dysphoric disorder: data from 1 099 women from STEP-BD study. Acta Psychiatr Scand. 2017 11; 136(5):473-482. PMID: 28846801.
    View in: PubMed
  5. Ketter TA, Sachs GS, Durgam S, Lu K, Starace A, Laszlovszky I, Németh G. The safety and tolerability of cariprazine in patients with manic or mixed episodes associated with bipolar I disorder: A 16-week open-label study. J Affect Disord. 2018 01 01; 225:350-356. PMID: 28843918.
    View in: PubMed
  6. Mahableshwarkar AR, Calabrese JR, Macek TA, Budur K, Adefuye A, Dong X, Hanson E, Sachs GS. Efficacy and safety of sublingual ramelteon as an adjunctive therapy in the maintenance treatment of bipolar I disorder in adults: A phase 3, randomized controlled trial. J Affect Disord. 2017 10 15; 221:275-282. PMID: 28662460.
    View in: PubMed
  7. Calabrese JR, Gao K, Sachs G. Diagnosing Mania in the Age of DSM-5. Am J Psychiatry. 2017 01 01; 174(1):8-10. PMID: 28040998.
    View in: PubMed
  8. Ma Y, Gao H, Yu X, Si T, Wang G, Fang Y, Liu Z, Sun J, Yang H, Wang X, Li J, Zhang Y, Sachs G. Bipolar diagnosis in China: Evaluating diagnostic confidence using the Bipolarity Index. J Affect Disord. 2016 09 15; 202:247-53. PMID: 27286368.
    View in: PubMed
  9. Daniel D, Kalali A, West M, Walling D, Hilt D, Engelhardt N, Alphs L, Loebel A, Vanover K, Atkinson S, Opler M, Sachs G, Nations K, Brady C. Data Quality Monitoring in Clinical Trials: Has It Been Worth It? An Evaluation and Prediction of the Future by All Stakeholders. Innov Clin Neurosci. 2016 Jan-Feb; 13(1-2):27-33. PMID: 27413584; PMCID: PMC4896826.
  10. Szabo ST, Kinon BJ, Brannan SK, Krystal AK, van Gerven JM, Mahableshwarkar A, Sachs GS. Lessons Learned and Potentials for Improvement in CNS Drug Development: ISCTM Section on Designing the Right Series of Experiments. Innov Clin Neurosci. 2015 Mar-Apr; 12(3-4):11S-25S. PMID: 25977837; PMCID: PMC4571294.
  11. Nierenberg AA, McIntyre RS, Sachs GS. Improving outcomes in patients with bipolar depression: a comprehensive review. J Clin Psychiatry. 2015 Mar; 76(3):e10. PMID: 25830453.
    View in: PubMed
  12. Aiken CB, Weisler RH, Sachs GS. The Bipolarity Index: a clinician-rated measure of diagnostic confidence. J Affect Disord. 2015 May 15; 177:59-64. PMID: 25745836.
    View in: PubMed
  13. Sachs GS, Greenberg WM, Starace A, Lu K, Ruth A, Laszlovszky I, Németh G, Durgam S. Cariprazine in the treatment of acute mania in bipolar I disorder: a double-blind, placebo-controlled, phase III trial. J Affect Disord. 2015 Mar 15; 174:296-302. PMID: 25532076.
    View in: PubMed
  14. Sachs GS, Ketter TA. Update on best practices for managing bipolar depression. J Clin Psychiatry. 2014 May; 75(5):e413-6. PMID: 24922493.
    View in: PubMed
  15. Loebel A, Cucchiaro J, Silva R, Kroger H, Hsu J, Sarma K, Sachs G. Lurasidone monotherapy in the treatment of bipolar I depression: a randomized, double-blind, placebo-controlled study. Am J Psychiatry. 2014 Feb; 171(2):160-8. PMID: 24170180.
    View in: PubMed
  16. Pacchiarotti I, Bond DJ, Baldessarini RJ, Nolen WA, Grunze H, Licht RW, Post RM, Berk M, Goodwin GM, Sachs GS, Tondo L, Findling RL, Youngstrom EA, Tohen M, Undurraga J, González-Pinto A, Goldberg JF, Yildiz A, Altshuler LL, Calabrese JR, Mitchell PB, Thase ME, Koukopoulos A, Colom F, Frye MA, Malhi GS, Fountoulakis KN, Vázquez G, Perlis RH, Ketter TA, Cassidy F, Akiskal H, Azorin JM, Valentí M, Mazzei DH, Lafer B, Kato T, Mazzarini L, Martínez-Aran A, Parker G, Souery D, Ozerdem A, McElroy SL, Girardi P, Bauer M, Yatham LN, Zarate CA, Nierenberg AA, Birmaher B, Kanba S, El-Mallakh RS, Serretti A, Rihmer Z, Young AH, Kotzalidis GD, MacQueen GM, Bowden CL, Ghaemi SN, Lopez-Jaramillo C, Rybakowski J, Ha K, Perugi G, Kasper S, Amsterdam JD, Hirschfeld RM, Kapczinski F, Vieta E. The International Society for Bipolar Disorders (ISBD) task force report on antidepressant use in bipolar disorders. Am J Psychiatry. 2013 Nov; 170(11):1249-62. PMID: 24030475.
    View in: PubMed
  17. Sachs GS, Peters AT, Sylvia L, Grunze H. Polypharmacy and bipolar disorder: what's personality got to do with it? Int J Neuropsychopharmacol. 2014 Jul; 17(7):1053-61. PMID: 24067291.
    View in: PubMed
  18. Sachs GS. Unmet needs in the assessment and management of bipolar I depression. J Clin Psychiatry. 2013 Jun; 74(6):e11. PMID: 23842019.
    View in: PubMed
  19. Sylvia LG, Hay A, Ostacher MJ, Miklowitz DJ, Nierenberg AA, Thase ME, Sachs GS, Deckersbach T, Perlis RH. Association between therapeutic alliance, care satisfaction, and pharmacological adherence in bipolar disorder. J Clin Psychopharmacol. 2013 Jun; 33(3):343-50. PMID: 23609394; PMCID: PMC3873324.
  20. Sachs GS, Vanderburg DG, Karayal ON, Kolluri S, Bachinsky M, Cavus I. Adjunctive oral ziprasidone in patients with acute mania treated with lithium or divalproex, part 1: results of a randomized, double-blind, placebo-controlled trial. J Clin Psychiatry. 2012 Nov; 73(11):1412-9. PMID: 23218157.
    View in: PubMed
  21. Sachs GS, Vanderburg DG, Edman S, Karayal ON, Kolluri S, Bachinsky M, Cavus I. Adjunctive oral ziprasidone in patients with acute mania treated with lithium or divalproex, part 2: influence of protocol-specific eligibility criteria on signal detection. J Clin Psychiatry. 2012 Nov; 73(11):1420-5. PMID: 23218158.
    View in: PubMed
  22. Lombardo I, Sachs G, Kolluri S, Kremer C, Yang R. Two 6-week, randomized, double-blind, placebo-controlled studies of ziprasidone in outpatients with bipolar I depression: did baseline characteristics impact trial outcome? J Clin Psychopharmacol. 2012 Aug; 32(4):470-8. PMID: 22722504.
    View in: PubMed
  23. Sachs G, Winklbaur B, Jagsch R, Lasser I, Kryspin-Exner I, Frommann N, Wölwer W. Training of affect recognition (TAR) in schizophrenia--impact on functional outcome. Schizophr Res. 2012 Jul; 138(2-3):262-7. PMID: 22464728.
    View in: PubMed
  24. Sachs GS, Ice KS, Chappell PB, Schwartz JH, Gurtovaya O, Vanderburg DG, Kasuba B. Efficacy and safety of adjunctive oral ziprasidone for acute treatment of depression in patients with bipolar I disorder: a randomized, double-blind, placebo-controlled trial. J Clin Psychiatry. 2011 Oct; 72(10):1413-22. PMID: 21672493.
    View in: PubMed
  25. Sylvia LG, Dupuy JM, Ostacher MJ, Cowperthwait CM, Hay AC, Sachs GS, Nierenberg AA, Perlis RH. Sleep disturbance in euthymic bipolar patients. J Psychopharmacol. 2012 Aug; 26(8):1108-12. PMID: 21965189; PMCID: PMC3787715.
  26. Kemp DE, Karayal ON, Calabrese JR, Sachs GS, Pappadopulos E, Ice KS, Siu CO, Vieta E. Ziprasidone with adjunctive mood stabilizer in the maintenance treatment of bipolar I disorder: long-term changes in weight and metabolic profiles. Eur Neuropsychopharmacol. 2012 Feb; 22(2):123-31. PMID: 21798721; PMCID: PMC3225596.
  27. Gruber J, Miklowitz DJ, Harvey AG, Frank E, Kupfer D, Thase ME, Sachs GS, Ketter TA. Sleep matters: sleep functioning and course of illness in bipolar disorder. J Affect Disord. 2011 Nov; 134(1-3):416-20. PMID: 21683450; PMCID: PMC3387668.
  28. Bowden CL, Perlis RH, Thase ME, Ketter TA, Ostacher MM, Calabrese JR, Reilly-Harrington NA, Gonzalez JM, Singh V, Nierenberg AA, Sachs GS. Aims and results of the NIMH systematic treatment enhancement program for bipolar disorder (STEP-BD). CNS Neurosci Ther. 2012 Mar; 18(3):243-9. PMID: 22070541.
    View in: PubMed
  29. Sachs GS, Dupuy JM, Wittmann CW. The pharmacologic treatment of bipolar disorder. J Clin Psychiatry. 2011 May; 72(5):704-15. PMID: 21658351.
    View in: PubMed
  30. Dias RS, Lafer B, Russo C, Del Debbio A, Nierenberg AA, Sachs GS, Joffe H. Longitudinal follow-up of bipolar disorder in women with premenstrual exacerbation: findings from STEP-BD. Am J Psychiatry. 2011 Apr; 168(4):386-94. PMID: 21324951.
    View in: PubMed
  31. Barnett JH, Huang J, Perlis RH, Young MM, Rosenbaum JF, Nierenberg AA, Sachs G, Nimgaonkar VL, Miklowitz DJ, Smoller JW. Personality and bipolar disorder: dissecting state and trait associations between mood and personality. Psychol Med. 2011 Aug; 41(8):1593-604. PMID: 21134316.
    View in: PubMed
  32. Deckersbach T, Nierenberg AA, Kessler R, Lund HG, Ametrano RM, Sachs G, Rauch SL, Dougherty D. RESEARCH: Cognitive rehabilitation for bipolar disorder: An open trial for employed patients with residual depressive symptoms. CNS Neurosci Ther. 2010 Oct; 16(5):298-307. PMID: 19895584; PMCID: PMC2888654.
  33. Perlis RH, Ostacher MJ, Goldberg JF, Miklowitz DJ, Friedman E, Calabrese J, Thase ME, Sachs GS. Transition to mania during treatment of bipolar depression. Neuropsychopharmacology. 2010 Dec; 35(13):2545-52. PMID: 20827274; PMCID: PMC3055576.
  34. Huang J, Perlis RH, Lee PH, Rush AJ, Fava M, Sachs GS, Lieberman J, Hamilton SP, Sullivan P, Sklar P, Purcell S, Smoller JW. Cross-disorder genomewide analysis of schizophrenia, bipolar disorder, and depression. Am J Psychiatry. 2010 Oct; 167(10):1254-63. PMID: 20713499.
    View in: PubMed
  35. Reilly-Harrington NA, DeBonis D, Leon AC, Sylvia L, Perlis R, Lewis D, Sachs GS. The interactive computer interview for mania. Bipolar Disord. 2010 Aug; 12(5):521-7. PMID: 20712753; PMCID: PMC2925290.
  36. Sachs G, Winklbaur B, Jagsch R, Keefe RS. Validation of the German version of the brief assessment of cognition in Schizophrenia (BACS) - preliminary results. Eur Psychiatry. 2011 Mar; 26(2):74-7. PMID: 20427153.
    View in: PubMed
  37. Ghaemi SN, Ostacher MM, El-Mallakh RS, Borrelli D, Baldassano CF, Kelley ME, Filkowski MM, Hennen J, Sachs GS, Goodwin FK, Baldessarini RJ. Antidepressant discontinuation in bipolar depression: a Systematic Treatment Enhancement Program for Bipolar Disorder (STEP-BD) randomized clinical trial of long-term effectiveness and safety. J Clin Psychiatry. 2010 Apr; 71(4):372-80. PMID: 20409444.
    View in: PubMed
  38. Perlis RH, Ostacher MJ, Miklowitz DJ, Hay A, Nierenberg AA, Thase ME, Sachs GS. Clinical features associated with poor pharmacologic adherence in bipolar disorder: results from the STEP-BD study. J Clin Psychiatry. 2010 Mar; 71(3):296-303. PMID: 20331931.
    View in: PubMed
  39. Perlis RH, Ostacher M, Fava M, Nierenberg AA, Sachs GS, Rosenbaum JF. Assuring that double-blind is blind. Am J Psychiatry. 2010 Mar; 167(3):250-2. PMID: 20194487.
    View in: PubMed
  40. Perlis RH, Ostacher MJ, Miklowitz DJ, Smoller JW, Dennehy EB, Cowperthwait C, Nierenberg AA, Thase ME, Sachs GS. Benzodiazepine use and risk of recurrence in bipolar disorder: a STEP-BD report. J Clin Psychiatry. 2010 Feb; 71(2):194-200. PMID: 20193647.
    View in: PubMed
  41. Furtner J, Prayer D, Sachs G. [Functional MRI in schizophrenia. Diagnostics and therapy monitoring of cognitive deficits of schizophrenic patients by functional MRI]. Radiologe. 2010 Feb; 50(2):131-5. PMID: 20076939.
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  42. Casamassima F, Huang J, Fava M, Sachs GS, Smoller JW, Cassano GB, Lattanzi L, Fagerness J, Stange JP, Perlis RH. Phenotypic effects of a bipolar liability gene among individuals with major depressive disorder. Am J Med Genet B Neuropsychiatr Genet. 2010 Jan 05; 153B(1):303-9. PMID: 19388002.
    View in: PubMed
  43. Fan J, Ionita-Laza I, McQueen MB, Devlin B, Purcell S, Faraone SV, Allen MH, Bowden CL, Calabrese JR, Fossey MD, Friedman ES, Gyulai L, Hauser P, Ketter TB, Marangell LB, Miklowitz DJ, Nierenberg AA, Patel JK, Sachs GS, Thase ME, Molay FB, Escamilla MA, Nimgaonkar VL, Sklar P, Laird NM, Smoller JW. Linkage disequilibrium mapping of the chromosome 6q21-22.31 bipolar I disorder susceptibility locus. Am J Med Genet B Neuropsychiatr Genet. 2010 Jan 05; 153B(1):29-37. PMID: 19308960; PMCID: PMC4067321.
  44. Ostacher MJ, Perlis RH, Nierenberg AA, Calabrese J, Stange JP, Salloum I, Weiss RD, Sachs GS. Impact of substance use disorders on recovery from episodes of depression in bipolar disorder patients: prospective data from the Systematic Treatment Enhancement Program for Bipolar Disorder (STEP-BD). Am J Psychiatry. 2010 Mar; 167(3):289-97. PMID: 20008948; PMCID: PMC2918249.
  45. Kane JM, Barnes TR, Correll CU, Sachs G, Buckley P, Eudicone J, McQuade R, Tran QV, Pikalov A, Assunção-Talbott S. Evaluation of akathisia in patients with schizophrenia, schizoaffective disorder, or bipolar I disorder: a post hoc analysis of pooled data from short- and long-term aripiprazole trials. J Psychopharmacol. 2010 Jul; 24(7):1019-29. PMID: 20008446.
    View in: PubMed
  46. Perlis RH, Ostacher MJ, Uher R, Nierenberg AA, Casamassima F, Kansky C, Calabrese JR, Thase M, Sachs GS. Stability of symptoms across major depressive episodes in bipolar disorder. Bipolar Disord. 2009 Dec; 11(8):867-75. PMID: 19922555; PMCID: PMC3566555.
  47. Mansour HA, Talkowski ME, Wood J, Chowdari KV, McClain L, Prasad K, Montrose D, Fagiolini A, Friedman ES, Allen MH, Bowden CL, Calabrese J, El-Mallakh RS, Escamilla M, Faraone SV, Fossey MD, Gyulai L, Loftis JM, Hauser P, Ketter TA, Marangell LB, Miklowitz DJ, Nierenberg AA, Patel J, Sachs GS, Sklar P, Smoller JW, Laird N, Keshavan M, Thase ME, Axelson D, Birmaher B, Lewis D, Monk T, Frank E, Kupfer DJ, Devlin B, Nimgaonkar VL. Association study of 21 circadian genes with bipolar I disorder, schizoaffective disorder, and schizophrenia. Bipolar Disord. 2009 Nov; 11(7):701-10. PMID: 19839995; PMCID: PMC3401899.
  48. Ostacher MJ, Lebeau RT, Perlis RH, Nierenberg AA, Lund HG, Moshier SJ, Sachs GS, Simon NM. Cigarette smoking is associated with suicidality in bipolar disorder. Bipolar Disord. 2009 Nov; 11(7):766-71. PMID: 19840000; PMCID: PMC2918237.
  49. Klein M, Gauggel S, Sachs G, Pohl W. Impact of chronic obstructive pulmonary disease (COPD) on attention functions. Respir Med. 2010 Jan; 104(1):52-60. PMID: 19748260.
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  50. Ng F, Mammen OK, Wilting I, Sachs GS, Ferrier IN, Cassidy F, Beaulieu S, Yatham LN, Berk M. The International Society for Bipolar Disorders (ISBD) consensus guidelines for the safety monitoring of bipolar disorder treatments. Bipolar Disord. 2009 Sep; 11(6):559-95. PMID: 19689501.
    View in: PubMed
  51. Tohen M, Frank E, Bowden CL, Colom F, Ghaemi SN, Yatham LN, Malhi GS, Calabrese JR, Nolen WA, Vieta E, Kapczinski F, Goodwin GM, Suppes T, Sachs GS, Chengappa KR, Grunze H, Mitchell PB, Kanba S, Berk M. The International Society for Bipolar Disorders (ISBD) Task Force report on the nomenclature of course and outcome in bipolar disorders. Bipolar Disord. 2009 Aug; 11(5):453-73. PMID: 19624385.
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  52. Kogan JN, Bauer MS, Dennehy EB, Miklowitz DJ, Gonzalez JM, Thompson PM, Sachs GS. Increasing minority research participation through collaboration with community outpatient clinics: the STEP-BD Community Partners Experience. Clin Trials. 2009 Aug; 6(4):344-54. PMID: 19587069.
    View in: PubMed
  53. Perlis RH, Dennehy EB, Miklowitz DJ, Delbello MP, Ostacher M, Calabrese JR, Ametrano RM, Wisniewski SR, Bowden CL, Thase ME, Nierenberg AA, Sachs G. Retrospective age at onset of bipolar disorder and outcome during two-year follow-up: results from the STEP-BD study. Bipolar Disord. 2009 Jun; 11(4):391-400. PMID: 19500092; PMCID: PMC3992980.
  54. Hlubocky FJ, Larson E, Ratain MJ, Sachs G, Daugherty CK. Cognitive function (CF) and prognostic information understanding in advanced cancer patients (ACP). J Clin Oncol. 2009 May 20; 27(15_suppl):9516. PMID: 27964487.
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  55. Perlis RH, Smoller JW, Ferreira MA, McQuillin A, Bass N, Lawrence J, Sachs GS, Nimgaonkar V, Scolnick EM, Gurling H, Sklar P, Purcell S. A genomewide association study of response to lithium for prevention of recurrence in bipolar disorder. Am J Psychiatry. 2009 Jun; 166(6):718-25. PMID: 19448189; PMCID: PMC3908470.
  56. Goldberg JF, Brooks JO, Kurita K, Hoblyn JC, Ghaemi SN, Perlis RH, Miklowitz DJ, Ketter TA, Sachs GS, Thase ME. Depressive illness burden associated with complex polypharmacy in patients with bipolar disorder: findings from the STEP-BD. J Clin Psychiatry. 2009 Feb; 70(2):155-62. PMID: 19210946.
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  57. Kaufman RE, Ostacher MJ, Marks EH, Simon NM, Sachs GS, Jensen JE, Renshaw PF, Pollack MH. Brain GABA levels in patients with bipolar disorder. Prog Neuropsychopharmacol Biol Psychiatry. 2009 Apr 30; 33(3):427-34. PMID: 19171176.
    View in: PubMed
  58. Goldberg JF, Perlis RH, Bowden CL, Thase ME, Miklowitz DJ, Marangell LB, Calabrese JR, Nierenberg AA, Sachs GS. Manic symptoms during depressive episodes in 1,380 patients with bipolar disorder: findings from the STEP-BD. Am J Psychiatry. 2009 Feb; 166(2):173-81. PMID: 19122008.
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  59. Busch AB, Frank RG, Sachs G, Normand SL. Bipolar-I patient characteristics associated with differences in antimanic medication prescribing. Psychopharmacol Bull. 2009; 42(1):35-49. PMID: 19204650; PMCID: PMC2648065.
  60. Iosifescu DV, Moore CM, Deckersbach T, Tilley CA, Ostacher MJ, Sachs GS, Nierenberg AA. Galantamine-ER for cognitive dysfunction in bipolar disorder and correlation with hippocampal neuronal viability: a proof-of-concept study. CNS Neurosci Ther. 2009; 15(4):309-19. PMID: 19889129.
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  61. Tohen M, Sutton VK, Calabrese JR, Sachs GS, Bowden CL. Maintenance of response following stabilization of mixed index episodes with olanzapine monotherapy in a randomized, double-blind, placebo-controlled study of bipolar 1 disorder. J Affect Disord. 2009 Jul; 116(1-2):43-50. PMID: 19054570.
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  62. Deckersbach T, Rauch SL, Buhlmann U, Ostacher MJ, Beucke JC, Nierenberg AA, Sachs G, Dougherty DD. An fMRI investigation of working memory and sadness in females with bipolar disorder: a brief report. Bipolar Disord. 2008 Dec; 10(8):928-42. PMID: 19594508.
    View in: PubMed
  63. Ferreira MA, O'Donovan MC, Meng YA, Jones IR, Ruderfer DM, Jones L, Fan J, Kirov G, Perlis RH, Green EK, Smoller JW, Grozeva D, Stone J, Nikolov I, Chambert K, Hamshere ML, Nimgaonkar VL, Moskvina V, Thase ME, Caesar S, Sachs GS, Franklin J, Gordon-Smith K, Ardlie KG, Gabriel SB, Fraser C, Blumenstiel B, Defelice M, Breen G, Gill M, Morris DW, Elkin A, Muir WJ, McGhee KA, Williamson R, MacIntyre DJ, MacLean AW, St CD, Robinson M, Van Beck M, Pereira AC, Kandaswamy R, McQuillin A, Collier DA, Bass NJ, Young AH, Lawrence J, Ferrier IN, Anjorin A, Farmer A, Curtis D, Scolnick EM, McGuffin P, Daly MJ, Corvin AP, Holmans PA, Blackwood DH, Gurling HM, Owen MJ, Purcell SM, Sklar P, Craddock N. Collaborative genome-wide association analysis supports a role for ANK3 and CACNA1C in bipolar disorder. Nat Genet. 2008 Sep; 40(9):1056-8. PMID: 18711365.
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  64. Gruber J, Harvey AG, Wang PW, Brooks JO, Thase ME, Sachs GS, Ketter TA. Sleep functioning in relation to mood, function, and quality of life at entry to the Systematic Treatment Enhancement Program for Bipolar Disorder (STEP-BD). J Affect Disord. 2009 Apr; 114(1-3):41-9. PMID: 18707765; PMCID: PMC2677624.
  65. Ostacher MJ, Nierenberg AA, Iosifescu DV, Eidelman P, Lund HG, Ametrano RM, Kaczynski R, Calabrese J, Miklowitz DJ, Sachs GS, Perlick DA. Correlates of subjective and objective burden among caregivers of patients with bipolar disorder. Acta Psychiatr Scand. 2008 Jul; 118(1):49-56. PMID: 18582347.
    View in: PubMed
  66. El-Mallakh RS, Ghaemi SN, Sagduyu K, Thase ME, Wisniewski SR, Nierenberg AA, Zhang HW, Pardo TA, Sachs G. Antidepressant-associated chronic irritable dysphoria (ACID) in STEP-BD patients. J Affect Disord. 2008 Dec; 111(2-3):372-7. PMID: 18565592.
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  67. Perlick DA, Rosenheck RA, Miklowitz DJ, Kaczynski R, Link B, Ketter T, Wisniewski S, Wolff N, Sachs G. Caregiver burden and health in bipolar disorder: a cluster analytic approach. J Nerv Ment Dis. 2008 Jun; 196(6):484-91. PMID: 18552626; PMCID: PMC4006696.
  68. Sachs GS. Psychosocial interventions as adjunctive therapy for bipolar disorder. J Psychiatr Pract. 2008 May; 14 Suppl 2:39-44. PMID: 18677198.
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  69. Nowakowska C, Sachs GS, Zarate CA, Marangell LB, Calabrese JR, Goldberg JF, Ketter TA. Increased rate of non-right-handedness in patients with bipolar disorder. J Clin Psychiatry. 2008 May; 69(5):866-7. PMID: 18681768.
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  70. Sklar P, Smoller JW, Fan J, Ferreira MA, Perlis RH, Chambert K, Nimgaonkar VL, McQueen MB, Faraone SV, Kirby A, de Bakker PI, Ogdie MN, Thase ME, Sachs GS, Todd-Brown K, Gabriel SB, Sougnez C, Gates C, Blumenstiel B, Defelice M, Ardlie KG, Franklin J, Muir WJ, McGhee KA, MacIntyre DJ, McLean A, VanBeck M, McQuillin A, Bass NJ, Robinson M, Lawrence J, Anjorin A, Curtis D, Scolnick EM, Daly MJ, Blackwood DH, Gurling HM, Purcell SM. Whole-genome association study of bipolar disorder. Mol Psychiatry. 2008 Jun; 13(6):558-69. PMID: 18317468.
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  71. Schneck CD, Miklowitz DJ, Miyahara S, Araga M, Wisniewski S, Gyulai L, Allen MH, Thase ME, Sachs GS. The prospective course of rapid-cycling bipolar disorder: findings from the STEP-BD. Am J Psychiatry. 2008 Mar; 165(3):370-7; quiz 410. PMID: 18198271.
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  72. Gyulai L, Bauer MS, Marangell LB, Dennehy EB, Thase ME, Otto MW, Zhang H, Wisniewski SR, Miklowitz DJ, Rapaport MH, Baldassano CF, Sachs GS. Correlates of functioning in bipolar disorder. Psychopharmacol Bull. 2008; 41(4):51-64. PMID: 19015629.
    View in: PubMed
  73. Busch AB, Frank RG, Sachs G. Bipolar-I depression outpatient treatment quality and costs in usual care practice. Psychopharmacol Bull. 2008; 41(2):24-39. PMID: 18668015; PMCID: PMC2789767.
  74. Truman CJ, Goldberg JF, Ghaemi SN, Baldassano CF, Wisniewski SR, Dennehy EB, Thase ME, Sachs GS. Self-reported history of manic/hypomanic switch associated with antidepressant use: data from the Systematic Treatment Enhancement Program for Bipolar Disorder (STEP-BD). J Clin Psychiatry. 2007 Oct; 68(10):1472-9. PMID: 17960960.
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  75. Sachs GS, Gaulin BD, Gutierrez-Esteinou R, McQuade RD, Pikalov A, Pultz JA, Sanchez R, Marcus RN, Crandall DT. Antimanic response to aripiprazole in bipolar I disorder patients is independent of the agitation level at baseline. J Clin Psychiatry. 2007 Sep; 68(9):1377-83. PMID: 17915976.
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  76. Reilly-Harrington NA, Deckersbach T, Knauz R, Wu Y, Tran T, Eidelman P, Lund HG, Sachs G, Nierenberg AA. Cognitive behavioral therapy for rapid-cycling bipolar disorder: a pilot study. J Psychiatr Pract. 2007 Sep; 13(5):291-7. PMID: 17890977.
    View in: PubMed
  77. Goldberg JF, Perlis RH, Ghaemi SN, Calabrese JR, Bowden CL, Wisniewski S, Miklowitz DJ, Sachs GS, Thase ME. Adjunctive antidepressant use and symptomatic recovery among bipolar depressed patients with concomitant manic symptoms: findings from the STEP-BD. Am J Psychiatry. 2007 Sep; 164(9):1348-55. PMID: 17728419.
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  163. Sachs GS, Rush AJ. Response, remission, and recovery in bipolar disorders: what are the realistic treatment goals? J Clin Psychiatry. 2003; 64 Suppl 6:18-22; discussion 28. PMID: 12720476.
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  164. Otto MW, Reilly-Harrington N, Sachs GS. Psychoeducational and cognitive-behavioral strategies in the management of bipolar disorder. J Affect Disord. 2003 Jan; 73(1-2):171-81. PMID: 12507750.
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  165. Carlson GA, Jensen PS, Findling RL, Meyer RE, Calabrese J, DelBello MP, Emslie G, Flynn L, Goodwin F, Hellander M, Kowatch R, Kusumakar V, Laughren T, Leibenluft E, McCracken J, Nottelmann E, Pine D, Sachs G, Shaffer D, Simar R, Strober M, Weller EB, Wozniak J, Youngstrom EA. Methodological issues and controversies in clinical trials with child and adolescent patients with bipolar disorder: report of a consensus conference. J Child Adolesc Psychopharmacol. 2003; 13(1):13-27. PMID: 12804123.
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  166. Sachs GS. Decision tree for the treatment of bipolar disorder. J Clin Psychiatry. 2003; 64 Suppl 8:35-40. PMID: 12892540.
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  167. Hallén S, Björquist A, Ostlund-Lindqvist AM, Sachs G. Identification of a region of the ileal-type sodium/bile acid cotransporter interacting with a competitive bile acid transport inhibitor. Biochemistry. 2002 Dec 17; 41(50):14916-24. PMID: 12475240.
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  168. Zajecka JM, Weisler R, Sachs G, Swann AC, Wozniak P, Sommerville KW. A comparison of the efficacy, safety, and tolerability of divalproex sodium and olanzapine in the treatment of bipolar disorder. J Clin Psychiatry. 2002 Dec; 63(12):1148-55. PMID: 12523875.
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  169. Calabrese JR, Sullivan JR, Bowden CL, Suppes T, Goldberg JF, Sachs GS, Shelton MD, Goodwin FK, Frye MA, Kusumakar V. Rash in multicenter trials of lamotrigine in mood disorders: clinical relevance and management. J Clin Psychiatry. 2002 Nov; 63(11):1012-9. PMID: 12444815.
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  170. Frankle WG, Perlis RH, Deckersbach T, Grandin LD, Gray SM, Sachs GS, Nierenberg AA. Bipolar depression: relationship between episode length and antidepressant treatment. Psychol Med. 2002 Nov; 32(8):1417-23. PMID: 12455940.
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  171. Guille C, Sachs G. Clinical outcome of adjunctive topiramate treatment in a sample of refractory bipolar patients with comorbid conditions. Prog Neuropsychopharmacol Biol Psychiatry. 2002 Oct; 26(6):1035-9. PMID: 12452523.
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  172. Sachs GS, Guille C, McMurrich SL. A clinical monitoring form for mood disorders. Bipolar Disord. 2002 Oct; 4(5):323-7. PMID: 12479665.
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  173. Wagner KD, Weller EB, Carlson GA, Sachs G, Biederman J, Frazier JA, Wozniak P, Tracy K, Weller RA, Bowden C. An open-label trial of divalproex in children and adolescents with bipolar disorder. J Am Acad Child Adolesc Psychiatry. 2002 Oct; 41(10):1224-30. PMID: 12364844.
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  174. Sachs GS, Grossman F, Ghaemi SN, Okamoto A, Bowden CL. Combination of a mood stabilizer with risperidone or haloperidol for treatment of acute mania: a double-blind, placebo-controlled comparison of efficacy and safety. Am J Psychiatry. 2002 Jul; 159(7):1146-54. PMID: 12091192.
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  175. Perlis RH, Sachs GS, Lafer B, Otto MW, Faraone SV, Kane JM, Rosenbaum JF. Effect of abrupt change from standard to low serum levels of lithium: a reanalysis of double-blind lithium maintenance data. Am J Psychiatry. 2002 Jul; 159(7):1155-9. PMID: 12091193.
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  176. Hallén S, Mareninova O, Brändén M, Sachs G. Organization of the membrane domain of the human liver sodium/bile acid cotransporter. Biochemistry. 2002 Jun 11; 41(23):7253-66. PMID: 12044156.
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  177. Suppes T, Dennehy EB, Swann AC, Bowden CL, Calabrese JR, Hirschfeld RM, Keck PE, Sachs GS, Crismon ML, Toprac MG, Shon SP. Report of the Texas Consensus Conference Panel on medication treatment of bipolar disorder 2000. J Clin Psychiatry. 2002 Apr; 63(4):288-99. PMID: 12004801.
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  178. Charney DS, Nemeroff CB, Lewis L, Laden SK, Gorman JM, Laska EM, Borenstein M, Bowden CL, Caplan A, Emslie GJ, Evans DL, Geller B, Grabowski LE, Herson J, Kalin NH, Keck PE, Kirsch I, Krishnan KR, Kupfer DJ, Makuch RW, Miller FG, Pardes H, Post R, Reynolds MM, Roberts L, Rosenbaum JF, Rosenstein DL, Rubinow DR, Rush AJ, Ryan ND, Sachs GS, Schatzberg AF, Solomon S. National Depressive and Manic-Depressive Association consensus statement on the use of placebo in clinical trials of mood disorders. Arch Gen Psychiatry. 2002 Mar; 59(3):262-70. PMID: 11879164.
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  179. Tohen M, Chengappa KN, Suppes T, Zarate CA, Calabrese JR, Bowden CL, Sachs GS, Kupfer DJ, Baker RW, Risser RC, Keeter EL, Feldman PD, Tollefson GD, Breier A. Efficacy of olanzapine in combination with valproate or lithium in the treatment of mania in patients partially nonresponsive to valproate or lithium monotherapy. Arch Gen Psychiatry. 2002 Jan; 59(1):62-9. PMID: 11779284.
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  180. Kupfer DJ, Chengappa KN, Gelenberg AJ, Hirschfeld RM, Goldberg JF, Sachs GS, Grochocinski VJ, Houck PR, Kolar AB. Citalopram as adjunctive therapy in bipolar depression. J Clin Psychiatry. 2001 Dec; 62(12):985-90. PMID: 11780881.
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  181. Yýldýz A, Sachs GS. Administration of antidepressants. Single versus split dosing: a meta-analysis. J Affect Disord. 2001 Oct; 66(2-3):199-206. PMID: 11578673.
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  182. Kraut JA, Helander KG, Helander HF, Iroezi ND, Marcus EA, Sachs G. Detection and localization of H+-K+-ATPase isoforms in human kidney. Am J Physiol Renal Physiol. 2001 Oct; 281(4):F763-8. PMID: 11553523.
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  183. Yildiz A, Demopulos CM, Moore CM, Renshaw PF, Sachs GS. Effect of lithium on phosphoinositide metabolism in human brain: a proton decoupled (31)P magnetic resonance spectroscopy study. Biol Psychiatry. 2001 Jul 01; 50(1):3-7. PMID: 11457417.
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  184. Nemeroff CB, Evans DL, Gyulai L, Sachs GS, Bowden CL, Gergel IP, Oakes R, Pitts CD. Double-blind, placebo-controlled comparison of imipramine and paroxetine in the treatment of bipolar depression. Am J Psychiatry. 2001 Jun; 158(6):906-12. PMID: 11384898.
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  185. Yildiz A, Sachs GS, Dorer DJ, Renshaw PF. 31P Nuclear magnetic resonance spectroscopy findings in bipolar illness: a meta-analysis. Psychiatry Res. 2001 May 30; 106(3):181-91. PMID: 11382540.
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  186. Sachs G, Katschnig H. [Cognitive dysfunction in schizophrenic psychoses. Drug and psychological treatment choices]. Psychiatr Prax. 2001 Mar; 28(2):60-8. PMID: 11305160.
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  187. Sachs GS. A 25-year-old woman with bipolar disorder. JAMA. 2001 Jan 24-31; 285(4):454-62. PMID: 11242431.
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  188. Sachs GS, Yan LJ, Swann AC, Allen MH. Integration of suicide prevention into outpatient management of bipolar disorder. J Clin Psychiatry. 2001; 62 Suppl 25:3-11. PMID: 11765093.
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  189. Grandin LD, Yan LJ, Gray SM, Jamison KR, Sachs GS. Suicide prevention: increasing education and awareness. J Clin Psychiatry. 2001; 62 Suppl 25:12-6. PMID: 11765090.
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  190. Hirschfeld RM, Williams JB, Spitzer RL, Calabrese JR, Flynn L, Keck PE, Lewis L, McElroy SL, Post RM, Rapport DJ, Russell JM, Sachs GS, Zajecka J. Development and validation of a screening instrument for bipolar spectrum disorder: the Mood Disorder Questionnaire. Am J Psychiatry. 2000 Nov; 157(11):1873-5. PMID: 11058490.
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  191. Calabrese JR, Suppes T, Bowden CL, Sachs GS, Swann AC, McElroy SL, Kusumakar V, Ascher JA, Earl NL, Greene PL, Monaghan ET. A double-blind, placebo-controlled, prophylaxis study of lamotrigine in rapid-cycling bipolar disorder. Lamictal 614 Study Group. J Clin Psychiatry. 2000 Nov; 61(11):841-50. PMID: 11105737.
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  192. Thase ME, Sachs GS. Bipolar depression: pharmacotherapy and related therapeutic strategies. Biol Psychiatry. 2000 Sep 15; 48(6):558-72. PMID: 11018227.
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  193. Sachs GS, Thase ME. Bipolar disorder therapeutics: maintenance treatment. Biol Psychiatry. 2000 Sep 15; 48(6):573-81. PMID: 11018228.
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  194. Sporn J, Ghaemi SN, Sambur MR, Rankin MA, Recht J, Sachs GS, Rosenbaum JF, Fava M. Pramipexole augmentation in the treatment of unipolar and bipolar depression: a retrospective chart review. Ann Clin Psychiatry. 2000 Sep; 12(3):137-40. PMID: 10984002.
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  195. Bowden CL, Lecrubier Y, Bauer M, Goodwin G, Greil W, Sachs G. Maintenance therapies for classic and other forms of bipolar disorder. J Affect Disord. 2000 Sep; 59 Suppl 1:S57-S67. PMID: 11121827.
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  196. Sachs GS, Koslow CL, Ghaemi SN. The treatment of bipolar depression. Bipolar Disord. 2000 Sep; 2(3 Pt 2):256-60. PMID: 11249803.
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  197. Guille C, Sachs GS, Ghaemi SN. A naturalistic comparison of clozapine, risperidone, and olanzapine in the treatment of bipolar disorder. J Clin Psychiatry. 2000 Sep; 61(9):638-42. PMID: 11030483.
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  198. Kahn DA, Sachs GS, Printz DJ, Carpenter D, Docherty JP, Ross R. Medication treatment of bipolar disorder 2000: a summary of the expert consensus guidelines. J Psychiatr Pract. 2000 Jul; 6(4):197-211. PMID: 15990485.
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  199. Hallén S, Fryklund J, Sachs G. Inhibition of the human sodium/bile acid cotransporters by side-specific methanethiosulfonate sulfhydryl reagents: substrate-controlled accessibility of site of inactivation. Biochemistry. 2000 Jun 06; 39(22):6743-50. PMID: 10828993.
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  200. Wancata J, Meise U, Sachs G. [Prevalence of psychiatric disorders in elderly inpatients of medical and surgical departments]. Psychiatr Prax. 2000 May; 27(4):170-5. PMID: 17195509.
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  201. Ghaemi N, Sachs GS, Goodwin FK. What is to be done? Controversies in the diagnosis and treatment of manic-depressive illness. World J Biol Psychiatry. 2000 Apr; 1(2):65-74. PMID: 12607202.
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  202. Sachs GS, Printz DJ, Kahn DA, Carpenter D, Docherty JP. The Expert Consensus Guideline Series: Medication Treatment of Bipolar Disorder 2000. Postgrad Med. 2000 Apr; Spec No:1-104. PMID: 10895797.
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  203. Munson KB, Lambrecht N, Sachs G. Effects of mutations in M4 of the gastric H+,K+-ATPase on inhibition kinetics of SCH28080. Biochemistry. 2000 Mar 21; 39(11):2997-3004. PMID: 10715120.
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  204. Sachs GS, Baldassano CF, Truman CJ, Guille C. Comorbidity of attention deficit hyperactivity disorder with early- and late-onset bipolar disorder. Am J Psychiatry. 2000 Mar; 157(3):466-8. PMID: 10698829.
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  205. Lambrecht N, Munson K, Vagin O, Sachs G. Comparison of covalent with reversible inhibitor binding sites of the gastric H,K-ATPase by site-directed mutagenesis. J Biol Chem. 2000 Feb 11; 275(6):4041-8. PMID: 10660561.
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  206. Wolfe MM, Sachs G. Acid suppression: optimizing therapy for gastroduodenal ulcer healing, gastroesophageal reflux disease, and stress-related erosive syndrome. Gastroenterology. 2000 Feb; 118(2 Suppl 1):S9-31. PMID: 10868896.
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  207. Dar P, Sachs GS, Strassburger D, Bukovsky I, Arieli S. Ovarian function before and after salpingectomy in artificial reproductive technology patients. Hum Reprod. 2000 Jan; 15(1):142-4. PMID: 10611204.
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  208. Zeng N, Athmann C, Kang T, Lyu RM, Walsh JH, Ohning GV, Sachs G, Pisegna JR. PACAP type I receptor activation regulates ECL cells and gastric acid secretion. J Clin Invest. 1999 Nov; 104(10):1383-91. PMID: 10562300; PMCID: PMC409843.
  209. Goldstein LE, Sporn J, Brown S, Kim H, Finkelstein J, Gaffey GK, Sachs G, Stern TA. New-onset diabetes mellitus and diabetic ketoacidosis associated with olanzapine treatment. Psychosomatics. 1999 Sep-Oct; 40(5):438-43. PMID: 10479950.
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  210. Jain U, Blais MA, Otto MW, Hirshfeld DR, Sachs GS. Five-factor personality traits in patients with seasonal depression: treatment effects and comparisons with bipolar patients. J Affect Disord. 1999 Sep; 55(1):51-4. PMID: 10512606.
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  211. Burt T, Sachs GS, Demopulos C. Donepezil in treatment-resistant bipolar disorder. Biol Psychiatry. 1999 Apr 15; 45(8):959-64. PMID: 10386177.
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  212. Calabrese JR, Bowden CL, Sachs GS, Ascher JA, Monaghan E, Rudd GD. A double-blind placebo-controlled study of lamotrigine monotherapy in outpatients with bipolar I depression. Lamictal 602 Study Group. J Clin Psychiatry. 1999 Feb; 60(2):79-88. PMID: 10084633.
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  213. Ghaemi SN, Sachs GS, Chiou AM, Pandurangi AK, Goodwin K. Is bipolar disorder still underdiagnosed? Are antidepressants overutilized? J Affect Disord. 1999 Jan-Mar; 52(1-3):135-44. PMID: 10357026.
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  214. Sachs GS, Guille C. Weight gain associated with use of psychotropic medications. J Clin Psychiatry. 1999; 60 Suppl 21:16-9. PMID: 10548137.
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  215. Sachs GS, Gaughan S. Clinical practice guidelines: praise and problems. J Clin Psychiatry. 1999 Jan; 60(1):7-8. PMID: 10074871.
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  216. Zeng N, Kang T, Lyu RM, Wong H, Wen Y, Walsh JH, Sachs G, Pisegna JR. The pituitary adenylate cyclase activating polypeptide type 1 receptor (PAC1-R) is expressed on gastric ECL cells: evidence by immunocytochemistry and RT-PCR. Ann N Y Acad Sci. 1998 Dec 11; 865:147-56. PMID: 9928007.
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  217. Bauer MS, McBride L, Chase C, Sachs G, Shea N. Manual-based group psychotherapy for bipolar disorder: a feasibility study. J Clin Psychiatry. 1998 Sep; 59(9):449-55. PMID: 9771814.
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  218. Lambrecht N, Corbett Z, Bayle D, Karlish SJ, Sachs G. Identification of the site of inhibition by omeprazole of a alpha-beta fusion protein of the H,K-ATPase using site-directed mutagenesis. J Biol Chem. 1998 May 29; 273(22):13719-28. PMID: 9593713.
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  219. Melle-Milovanovic D, Milovanovic M, Nagpal S, Sachs G, Shin JM. Regions of association between the alpha and the beta subunit of the gastric H,K-ATPase. J Biol Chem. 1998 May 01; 273(18):11075-81. PMID: 9556592.
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  220. Kraut JA, Hiura J, Shin JM, Smolka A, Sachs G, Scott D. The Na(+)-K(+)-ATPase beta 1 subunit is associated with the HK alpha 2 protein in the rat kidney. Kidney Int. 1998 Apr; 53(4):958-62. PMID: 9551404.
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  221. Bayle D, Wängler S, Weitzenegger T, Steinhilber W, Volz J, Przybylski M, Schäfer KP, Sachs G, Melchers K. Properties of the P-type ATPases encoded by the copAP operons of Helicobacter pylori and Helicobacter felis. J Bacteriol. 1998 Jan; 180(2):317-29. PMID: 9440521; PMCID: PMC106887.
  222. Sachs GS, Cosgrove VE. Bipolar disorder: current treatments and new strategies. Cleve Clin J Med. 1998; 65 Suppl 1:SI31-7; discussion SI45-7. PMID: 12033204.
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  223. Vasile RG, Sachs G, Anderson JL, Lafer B, Matthews E, Hill T. Changes in regional cerebral blood flow following light treatment for seasonal affective disorder: responders versus nonresponders. Biol Psychiatry. 1997 Dec 01; 42(11):1000-5. PMID: 9386851.
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  224. Lafer B, Renshaw PF, Sachs GS. Major depression and the basal ganglia. Psychiatr Clin North Am. 1997 Dec; 20(4):885-96. PMID: 9443355.
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  225. Ghaemi SN, Sachs GS, Baldassano CF, Truman CJ. Insight in seasonal affective disorder. Compr Psychiatry. 1997 Nov-Dec; 38(6):345-8. PMID: 9406741.
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  226. Ghaemi SN, Sachs GS. Long-term risperidone treatment in bipolar disorder: 6-month follow up. Int Clin Psychopharmacol. 1997 Nov; 12(6):333-8. PMID: 9547135.
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  227. Bayle D, Weeks D, Sachs G. Identification of membrane insertion sequences of the rabbit gastric cholecystokinin-A receptor by in vitro translation. J Biol Chem. 1997 Aug 08; 272(32):19697-707. PMID: 9242625.
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  228. Sporn J, Sachs G. The anticonvulsant lamotrigine in treatment-resistant manic-depressive illness. J Clin Psychopharmacol. 1997 Jun; 17(3):185-9. PMID: 9169963.
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  229. Kraut JA, Hiura J, Besancon M, Smolka A, Sachs G, Scott D. Effect of hypokalemia on the abundance of HK alpha 1 and HK alpha 2 protein in the rat kidney. Am J Physiol. 1997 Jun; 272(6 Pt 2):F744-50. PMID: 9227635.
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  230. Ghaemi SN, Sachs GS, Baldassano CF, Truman CJ. Acute treatment of bipolar disorder with adjunctive risperidone in outpatients. Can J Psychiatry. 1997 Mar; 42(2):196-9. PMID: 9067070.
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  231. Fishman SM, Catarau EM, Sachs G, Stojanovic M, Borsook D. Corticosteroid-induced mania after single regional application at the celiac plexus. Anesthesiology. 1996 Nov; 85(5):1194-6. PMID: 8916839.
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  232. Stoll AL, Sachs GS, Cohen BM, Lafer B, Christensen JD, Renshaw PF. Choline in the treatment of rapid-cycling bipolar disorder: clinical and neurochemical findings in lithium-treated patients. Biol Psychiatry. 1996 Sep 01; 40(5):382-8. PMID: 8874839.
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  233. Sachs GS. Treatment-resistant bipolar depression. Psychiatr Clin North Am. 1996 Jun; 19(2):215-36. PMID: 8827187.
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  234. Matthew E, Vasile RG, Sachs G, Anderson J, Lafer B, Hill T. Regional cerebral blood flow changes after light therapy in seasonal affective disorder. Nucl Med Commun. 1996 Jun; 17(6):475-9. PMID: 8822744.
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  235. Moser G, Tillinger W, Sachs G, Maier-Dobersberger T, Wyatt J, Vogelsang H, Lochs H, Gangl A. Relationship between the use of unconventional therapies and disease-related concerns: a study of patients with inflammatory bowel disease. J Psychosom Res. 1996 May; 40(5):503-9. PMID: 8803859.
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  236. Sachs GS. Bipolar mood disorder: practical strategies for acute and maintenance phase treatment. J Clin Psychopharmacol. 1996 Apr; 16(2 Suppl 1):32S-47S. PMID: 8707998.
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  237. Baldassano CF, Truman CJ, Nierenberg A, Ghaemi SN, Sachs GS. Akathisia: a review and case report following paroxetine treatment. Compr Psychiatry. 1996 Mar-Apr; 37(2):122-4. PMID: 8654061.
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  238. Labbate LA, Lafer B, Thibault A, Rosenbaum JF, Sachs GS. Influence of phototherapy treatment duration for seasonal affective disorder: outcome at one vs. two weeks. Biol Psychiatry. 1995 Dec 01; 38(11):747-50. PMID: 8580228.
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  239. Sachs GS, Renshaw PF, Lafer B, Stoll AL, Guimarães AR, Rosenbaum JF, Gonzalez RG. Variability of brain lithium levels during maintenance treatment: a magnetic resonance spectroscopy study. Biol Psychiatry. 1995 Oct 01; 38(7):422-8. PMID: 8672602.
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  240. Moser G, Tillinger W, Sachs G, Genser D, Maier-Dobersberger T, Spiess K, Wyatt J, Vogelsang H, Lochs H, Gangl A. Disease-related worries and concerns: a study on out-patients with inflammatory bowel disease. Eur J Gastroenterol Hepatol. 1995 Sep; 7(9):853-8. PMID: 8574717.
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  241. Weilburg JB, Schachter S, Worth J, Pollack MH, Sachs GS, Ives JR, Schomer DL. EEG abnormalities in patients with atypical panic attacks. J Clin Psychiatry. 1995 Aug; 56(8):358-62. PMID: 7635852.
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  242. Sachs G, Rasoul-Rockenschaub S, Aschauer H, Spiess K, Göber I, Staffen A, Zielinski C. Lytic effector cell activity and major depressive disorder in patients with breast cancer: a prospective study. J Neuroimmunol. 1995 Jun; 59(1-2):83-9. PMID: 7797623.
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  243. Kraut JA, Starr F, Sachs G, Reuben M. Expression of gastric and colonic H(+)-K(+)-ATPase in the rat kidney. Am J Physiol. 1995 Apr; 268(4 Pt 2):F581-7. PMID: 7733314.
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  244. Sachs GS, Lafer B, Stoll AL, Banov M, Thibault AB, Tohen M, Rosenbaum JF. A double-blind trial of bupropion versus desipramine for bipolar depression. J Clin Psychiatry. 1994 Sep; 55(9):391-3. PMID: 7929019.
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  245. Lafer B, Sachs GS, Labbate LA, Thibault A, Rosenbaum JF. Phototherapy for seasonal affective disorder: a blind comparison of three different schedules. Am J Psychiatry. 1994 Jul; 151(7):1081-3. PMID: 8010369.
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  246. Labbate LA, Lafer B, Thibault A, Sachs GS. Side effects induced by bright light treatment for seasonal affective disorder. J Clin Psychiatry. 1994 May; 55(5):189-91. PMID: 8071268.
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  247. Spiess K, Sachs G, Moser G, Pietschmann P, Schernthaner G, Prager R. Psychological moderator variables and metabolic control in recent onset type 1 diabetic patients--a two year longitudinal study. J Psychosom Res. 1994 Apr; 38(3):249-58. PMID: 8027964.
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  248. Pollack MH, Otto MW, Sachs GS, Leon A, Shear MK, Deltito JA, Keller MB, Rosenbaum JF. Anxiety psychopathology predictive of outcome in patients with panic disorder and depression treated with imipramine, alprazolam and placebo. J Affect Disord. 1994 Apr; 30(4):273-81. PMID: 8014326.
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  249. Labbate LA, Sachs GS. Phototherapy-induced hot flushes. J Clin Psychopharmacol. 1994 Apr; 14(2):151. PMID: 8195461.
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  250. Otto MW, Pollack MH, Rosenbaum JF, Sachs GS, Asher RH. Childhood history of anxiety in adults with panic disorder: association with anxiety sensitivity and comorbidity. Harv Rev Psychiatry. 1994 Jan-Feb; 1(5):288-93. PMID: 9384860.
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  251. Spiess K, Sachs G, Frischenschlager O, Moser G, Prager R. [Phase-specific function of denial in type 1 diabetic patients after disease onset]. Z Psychosom Med Psychoanal. 1994; 40(1):52-67. PMID: 8147141.
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  252. Sachs G, Spiess K, Moser G, Kautzky A, Luger A, Pietschmann P, Schernthaner GS, Prager R. Hormonal and blood glucose responsiveness as an indicator of specific emotional arousal in type 1 diabetics. J Psychosom Res. 1993 Dec; 37(8):831-41. PMID: 8301623.
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  253. Otto MW, Pollack MH, Sachs GS, Reiter SR, Meltzer-Brody S, Rosenbaum JF. Discontinuation of benzodiazepine treatment: efficacy of cognitive-behavioral therapy for patients with panic disorder. Am J Psychiatry. 1993 Oct; 150(10):1485-90. PMID: 8379551.
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  254. González RG, Guimaraes AR, Sachs GS, Rosenbaum JF, Garwood M, Renshaw PF. Measurement of human brain lithium in vivo by MR spectroscopy. AJNR Am J Neuroradiol. 1993 Sep-Oct; 14(5):1027-37. PMID: 8237676.
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  255. Keller MB, Lavori PW, Goldenberg IM, Baker LA, Pollack MH, Sachs GS, Rosenbaum JF, Deltito JA, Leon A, Shear K, et al. Influence of depression on the treatment of panic disorder with imipramine, alprazolam and placebo. J Affect Disord. 1993 May; 28(1):27-38. PMID: 8326078.
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  256. Moser G, Koppensteiner R, Eckersberger F, Klepetko W, Sachs G, Schlick W. Postoperative complication rate of thoracotomy in patients with normal and abnormal pulmonary function. Wien Klin Wochenschr. 1993; 105(3):71-5. PMID: 8447123.
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  257. Weilburg JB, Schachter S, Sachs GS, Worth J, Pollack MH, Ives JR, Schomer DL. Focal paroxysmal EEG changes during atypical panic attacks. J Neuropsychiatry Clin Neurosci. 1993; 5(1):50-5. PMID: 8428135.
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  258. Stoll AL, Renshaw PF, Sachs GS, Guimaraes AR, Miller C, Cohen BM, Lafer B, Gonzalez RG. The human brain resonance of choline-containing compounds is similar in patients receiving lithium treatment and controls: an in vivo proton magnetic resonance spectroscopy study. Biol Psychiatry. 1992 Nov 15; 32(10):944-9. PMID: 1467379.
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  259. Kajimura M, Reuben MA, Sachs G. The muscarinic receptor gene expressed in rabbit parietal cells is the m3 subtype. Gastroenterology. 1992 Sep; 103(3):870-5. PMID: 1499937.
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  260. Pollack MH, Otto MW, Rosenbaum JF, Sachs GS. Personality disorders in patients with panic disorder: association with childhood anxiety disorders, early trauma, comorbidity, and chronicity. Compr Psychiatry. 1992 Mar-Apr; 33(2):78-83. PMID: 1544300.
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  261. Otto MW, Pollack MH, Sachs GS, O'Neil CA, Rosenbaum JF. Alcohol dependence in panic disorder patients. J Psychiatr Res. 1992 Jan; 26(1):29-38. PMID: 1560407.
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  262. Muallem S, Loessberg P, Sachs G, Wheeler LA. Agonist-sensitive and -insensitive intracellular Ca2+ pools. Separate Ca(2+)-releasing mechanisms revealed by manoalide and benzohydroquinone. Biochem J. 1991 Oct 15; 279 ( Pt 2):367-75. PMID: 1659378; PMCID: PMC1151615.
  263. Sachs G, Spiess K, Moser G, Prager R, Kunz A, Schernthaner G. [Glycosylated hemoglobin and diabetes--self monitoring (compliance) in depressed and non-depressed type I diabetic patients]. Psychother Psychosom Med Psychol. 1991 Aug; 41(8):306-12. PMID: 1946902.
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  264. Rabon E, Sachs G, Bassilian S, Leach C, Keeling D. A K(+)-competitive fluorescent inhibitor of the H,K-ATPase. J Biol Chem. 1991 Jul 05; 266(19):12395-401. PMID: 1648097.
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  265. Hall K, Perez G, Sachs G, Rabon E. Identification of H+/K(+)-ATPase alpha,beta-heterodimers. Biochim Biophys Acta. 1991 Apr 08; 1077(2):173-9. PMID: 1849747.
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  266. Pollack MH, Sachs GS, Tesar GE, Shushtari J, Herman JB, Otto MW, Rosenbaum JF. Pilot outreach services to homebound agoraphobic patients. Hosp Community Psychiatry. 1991 Mar; 42(3):315-7. PMID: 2030018.
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  267. Tesar GE, Rosenbaum JF, Pollack MH, Otto MW, Sachs GS, Herman JB, Cohen LS, Spier SA. Double-blind, placebo-controlled comparison of clonazepam and alprazolam for panic disorder. J Clin Psychiatry. 1991 Feb; 52(2):69-76. PMID: 1993639.
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  268. Zhao H, Loessberg PA, Sachs G, Muallem S. Regulation of intracellular Ca2+ oscillation in AR42J cells. J Biol Chem. 1990 Dec 05; 265(34):20856-62. PMID: 1701171.
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  269. Pollack MH, Otto MW, Rosenbaum JF, Sachs GS, O'Neil C, Asher R, Meltzer-Brody S. Longitudinal course of panic disorder: findings from the Massachusetts General Hospital Naturalistic Study. J Clin Psychiatry. 1990 Dec; 51 Suppl A:12-6. PMID: 2258371.
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  270. Rabon EC, Bassilian S, Sachs G, Karlish SJ. Conformational transitions of the H,K-ATPase studied with sodium ions as surrogates for protons. J Biol Chem. 1990 Nov 15; 265(32):19594-9. PMID: 2174045.
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  271. Reuben MA, Lasater LS, Sachs G. Characterization of a beta subunit of the gastric H+/K(+)-transporting ATPase. Proc Natl Acad Sci U S A. 1990 Sep; 87(17):6767-71. PMID: 2168558; PMCID: PMC54618.
  272. Muallem S, Zhao H, Mayer E, Sachs G. Regulation of intracellular calcium in epithelial cells. Semin Cell Biol. 1990 Aug; 1(4):305-10. PMID: 2103515.
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  273. Sachs GS. Use of clonazepam for bipolar affective disorder. J Clin Psychiatry. 1990 May; 51 Suppl:31-4; discussion 50-3. PMID: 1970815.
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  274. Muallem S, Khademazad M, Sachs G. The route of Ca2+ entry during reloading of the intracellular Ca2+ pool in pancreatic acini. J Biol Chem. 1990 Feb 05; 265(4):2011-6. PMID: 2105314.
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  275. Sachs GS, Rosenbaum JF, Jones L. Adjunctive clonazepam for maintenance treatment of bipolar affective disorder. J Clin Psychopharmacol. 1990 Feb; 10(1):42-7. PMID: 2106533.
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  276. Sachs GS, Weilburg JB, Rosenbaum JF. Clonazepam vs. neuroleptics as adjuncts to lithium maintenance. Psychopharmacol Bull. 1990; 26(1):137-43. PMID: 1973545.
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  277. Weilburg JB, Rosenbaum JF, Biederman J, Sachs GS, Pollack MH, Kelly K. Fluoxetine added to non-MAOI antidepressants converts nonresponders to responders: a preliminary report. J Clin Psychiatry. 1989 Dec; 50(12):447-9. PMID: 2600061.
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  278. Sachs GS. Adjuncts and alternatives to lithium therapy for bipolar affective disorder. J Clin Psychiatry. 1989 Dec; 50 Suppl:31-9; discussion 45-7. PMID: 2689435.
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  279. Demarest JR, Loo DD, Sachs G. Activation of apical chloride channels in the gastric oxyntic cell. Science. 1989 Jul 28; 245(4916):402-4. PMID: 2474200.
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  280. Moser G, Kiss A, Sachs G, Spiess K, Schwarzmeier J. [The significance of psychosocial complaints in the initial interview--a study of unselected patients of an internal medicine/polyclinic university ambulatory service]. Psychother Psychosom Med Psychol. 1989 May; 39(5):161-7. PMID: 2734431.
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  281. Sachs GS, Gelenberg AJ, Bellinghausen B, Wojcik J, Falk WE, Farhadi AM, Jenike M. Ergoloid mesylates and ECT. J Clin Psychiatry. 1989 Mar; 50(3):87-90. PMID: 2647711.
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  282. Hoge SK, Sachs G, Appelbaum PS, Greer A, Gordon C. Limitations on psychiatrists' discretionary civil commitment authority by the Stone and dangerousness criteria. Arch Gen Psychiatry. 1988 Aug; 45(8):764-9. PMID: 3395207.
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  283. Gelenberg AJ, Bellinghausen B, Wojcik JD, Falk WE, Sachs GS. A prospective survey of neuroleptic malignant syndrome in a short-term psychiatric hospital. Am J Psychiatry. 1988 Apr; 145(4):517-8. PMID: 2894782.
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  284. Weilburg JB, Sachs G, Falk WE. Triazolam-induced brief episodes of secondary mania in a depressed patient. J Clin Psychiatry. 1987 Dec; 48(12):492-3. PMID: 3693336.
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  285. Tesar GE, Rosenbaum JF, Pollack MH, Herman JB, Sachs GS, Mahoney EM, Cohen LS, McNamara M, Goldstein S. Clonazepam versus alprazolam in the treatment of panic disorder: interim analysis of data from a prospective, double-blind, placebo-controlled trial. J Clin Psychiatry. 1987 Oct; 48 Suppl:16-21. PMID: 3312179.
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  286. Chitayat D, Hahm SY, Marion RW, Sachs GS, Goldman D, Hutcheon RG, Weiss R, Cho S, Nitowsky HM. Further delineation of the McKusick-Kaufman hydrometrocolpos-polydactyly syndrome. Am J Dis Child. 1987 Oct; 141(10):1133-6. PMID: 3631003.
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  287. Weilburg JB, Bear DM, Sachs G. Three patients with concomitant panic attacks and seizure disorder: possible clues to the neurology of anxiety. Am J Psychiatry. 1987 Aug; 144(8):1053-6. PMID: 3605426.
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  288. Pollack MH, Rosenbaum JF, Tesar GE, Herman JB, Sachs GS. Clonazepam in the treatment of panic disorder and agoraphobia. Psychopharmacol Bull. 1987; 23(1):141-4. PMID: 3110854.
    View in: PubMed
  289. Sachs GS, Pollack MH, Brotman AW, Farhadi AM, Gelenberg AJ. Enhancement of ECT benefit by yohimbine. J Clin Psychiatry. 1986 Oct; 47(10):508-10. PMID: 3020009.
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  290. Nutzinger DO, Cayiroglu S, Sachs G, Zapotoczky HG. Emotional problems during weight reduction: advantages of a combined behavior therapy and antidepressive drug therapy for obesity. J Behav Ther Exp Psychiatry. 1985 Sep; 16(3):217-21. PMID: 4066968.
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  291. Sachs G. Pump blockers and ulcer disease. N Engl J Med. 1984 Mar 22; 310(12):785-6. PMID: 6230536.
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  292. Nutzinger DO, Cayiroglu S, Sachs G, Stellamor M, Zapotoczky HG. [A behaviorally oriented group therapy concept for the treatment of a risk group of obese patients]. Psychother Psychosom Med Psychol. 1983 Sep; 33 Suppl 2:102-9. PMID: 6635142.
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  293. Sachs G, Nutzinger D, Zapotoczky HG. [Diet triggered depression as well as its treatment: a behaviorally oriented group therapy concept]. Psychiatr Clin (Basel). 1982; 15(3):160-72. PMID: 7134487.
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Funded by the NIH/NCATS Clinical and Translational Science Award (CTSA) program, grant number UL1TR001102, and through institutional support from Harvard University, Harvard Medical School, Harvard T.H. Chan School of Public Health, Beth Israel Deaconess Medical Center, Boston Children's Hospital, Brigham and Women's Hospital, Massachusetts General Hospital and the Dana Farber Cancer Institute.