Harvard Catalyst Profiles

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Robert Layne Kruse, M.D.

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Johns Hopkins HospitalResidency2021Clinical Pathology
Baylor College of MedicineMD2018Medicine
Baylor College of MedicinePhD2016Translational Biology & Molecular Medicine
Yale UniversityBS2009Molecular Biophysics & Biochemistry

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Kruse RL, Albayda J, Vozniak SO, Lawrence CE, Goel R, Lokhandwala PM, Ness PM, Tobian AAR, Bloch EM, Crowe EP. Therapeutic plasma exchange for the treatment of refractory necrotizing autoimmune myopathy. J Clin Apher. 2022 Feb 04. PMID: 35119135.
    Citations:    Fields:    
  2. Kruse RL, Huang Y, Kumbhari V. How to Embrace Gene Therapy in Gastroenterology. Gastroenterology. 2022 Apr; 162(4):1019-1023. PMID: 35122741.
    Citations:    Fields:    
  3. Kruse RL, Huang Y, Lee A, Zhu X, Shrestha R, Laeyendecker O, Littlefield K, Pekosz A, Bloch EM, Tobian AAR, Wang ZZ. A Hemagglutination-Based Semiquantitative Test for Point-of-Care Determination of SARS-CoV-2 Antibody Levels. J Clin Microbiol. 2021 11 18; 59(12):e0118621. PMID: 34469185.
    Citations: 1     Fields:    Translation:HumansCellsPHPublic Health
  4. Kruse RL, Huang Y, Shum T, Bai L, Ding H, Wang ZZ, Selaru FM, Kumbhari V. Endoscopic-mediated, biliary hydrodynamic injection mediating clinically relevant levels of gene delivery in pig liver. Gastrointest Endosc. 2021 Dec; 94(6):1119-1130.e4. PMID: 34197834.
    Citations:    Fields:    Translation:Animals
  5. Kruse RL, Huang Y, Lee A, Zhu X, Shrestha R, Laeyendecker O, Littlefield K, Pekosz A, Bloch EM, Tobian AAR, Wang ZZ. A hemagglutination-based, semi-quantitative test for point-of-care determination of SARS-CoV-2 antibody levels. medRxiv. 2021 May 04. PMID: 33972952.
  6. Huang Y, Kruse RL, Ding H, Itani MI, Morrison J, Wang ZZ, Selaru FM, Kumbhari V. Parameters of biliary hydrodynamic injection during endoscopic retrograde cholangio-pancreatography in pigs for applications in gene delivery. PLoS One. 2021; 16(4):e0249931. PMID: 33909609.
    Citations: 1     Fields:    Translation:Animals
  7. Kruse RL, Huang Y, Smetana H, Gehrie EA, Amukele TK, Tobian AAR, Mostafa HH, Wang ZZ. A rapid, point-of-care red blood cell agglutination assay detecting antibodies against SARS-CoV-2. Biochem Biophys Res Commun. 2021 05 14; 553:165-171. PMID: 33773139.
    Citations: 6     Fields:    Translation:HumansCells
  8. Kruse RL, Barzi M, Legras X, Pankowicz FP, Furey N, Liao L, Xu J, Bissig-Choisat B, Slagle BL, Bissig KD. A hepatitis B virus transgenic mouse model with a conditional, recombinant, episomal genome. JHEP Rep. 2021 Apr; 3(2):100252. PMID: 33733079.
  9. Kruse RL, Legras X, Barzi M. Cre/LoxP-HBV plasmids generating recombinant covalently closed circular DNA genome upon transfection. Virus Res. 2021 01 15; 292:198224. PMID: 33166564.
    Citations: 2     Fields:    Translation:HumansCells
  10. Kruse RL, Neally M, Cho BC, Bloch EM, Lokhandwala PM, Ness PM, Frank SM, Tobian AAR, Gehrie EA. Cryoprecipitate Utilization Patterns Observed With a Required Prospective Approval Process vs Electronic Dosing Guidance. Am J Clin Pathol. 2020 08 05; 154(3):362-368. PMID: 32445461.
    Citations:    Fields:    Translation:Humans
  11. Kruse RL. Therapeutic strategies in an outbreak scenario to treat the novel coronavirus originating in Wuhan, China. F1000Res. 2020; 9:72. PMID: 32117569.
    Citations: 133     Fields:    Translation:HumansCellsPHPublic Health
  12. Lally K, Kruse RL, Smetana H, Davis R, Roots A, Marshall C, Ness PM, DeZern AE, Gladstone DE, Brennan DC, Desai NM, Tobian AAR, Bloch EM, Gehrie EA. Isohemagglutinin titering performed on an automated solid-phase and hemagglutinin-based analyzer is comparable to results obtained by manual gel testing. Transfusion. 2020 03; 60(3):628-636. PMID: 31957889.
    Citations:    Fields:    Translation:Humans
  13. Yang K, Kruse RL, Lin WV, Musher DM. Corynebacteria as a cause of pulmonary infection: a case series and literature review. Pneumonia (Nathan). 2018; 10:10. PMID: 30324081.
    Citations: 13     
  14. Shum T, Kruse RL, Rooney CM. Strategies for enhancing adoptive T-cell immunotherapy against solid tumors using engineered cytokine signaling and other modalities. Expert Opin Biol Ther. 2018 06; 18(6):653-664. PMID: 29727246.
    Citations: 11     Fields:    Translation:HumansAnimalsCells
  15. Kruse RL, Shum T, Tashiro H, Barzi M, Yi Z, Whitten-Bauer C, Legras X, Bissig-Choisat B, Garaigorta U, Gottschalk S, Bissig KD. HBsAg-redirected T cells exhibit antiviral activity in HBV-infected human liver chimeric mice. Cytotherapy. 2018 05; 20(5):697-705. PMID: 29631939.
    Citations: 18     Fields:    Translation:HumansAnimalsCells
  16. Kruse RL, Vanijcharoenkarn K. Drug repurposing to treat asthma and allergic disorders: Progress and prospects. Allergy. 2018 Feb; 73(2):313-322. PMID: 28880396.
    Citations: 6     Fields:    Translation:Humans
  17. Kruse RL, Shum T, Legras X, Barzi M, Pankowicz FP, Gottschalk S, Bissig KD. In Situ Liver Expression of HBsAg/CD3-Bispecific Antibodies for HBV Immunotherapy. Mol Ther Methods Clin Dev. 2017 Dec 15; 7:32-41. PMID: 29018834.
    Citations: 5     
  18. Shum T, Omer B, Tashiro H, Kruse RL, Wagner DL, Parikh K, Yi Z, Sauer T, Liu D, Parihar R, Castillo P, Liu H, Brenner MK, Metelitsa LS, Gottschalk S, Rooney CM. Constitutive Signaling from an Engineered IL7 Receptor Promotes Durable Tumor Elimination by Tumor-Redirected T Cells. Cancer Discov. 2017 11; 7(11):1238-1247. PMID: 28830878.
    Citations: 84     Fields:    Translation:HumansAnimalsCells
  19. Billioud G, Kruse RL, Carrillo M, Whitten-Bauer C, Gao D, Kim A, Chen L, McCaleb ML, Crosby JR, Hamatake R, Hong Z, Garaigorta U, Swayze E, Bissig KD, Wieland S. In vivo reduction of hepatitis B virus antigenemia and viremia by antisense oligonucleotides. J Hepatol. 2016 Apr; 64(4):781-9. PMID: 26658683.
    Citations: 19     Fields:    Translation:HumansAnimalsCells
  20. Bissig-Choisat B, Wang L, Legras X, Saha PK, Chen L, Bell P, Pankowicz FP, Hill MC, Barzi M, Leyton CK, Leung HE, Kruse RL, Himes RW, Goss JA, Wilson JM, Chan L, Lagor WR, Bissig KD. Development and rescue of human familial hypercholesterolaemia in a xenograft mouse model. Nat Commun. 2015 Jun 17; 6:7339. PMID: 26081744.
    Citations: 32     Fields:    Translation:HumansAnimalsCells
  21. Kruse RL, Kramer JR, Tyson GL, Duan Z, Chen L, El-Serag HB, Kanwal F. Clinical outcomes of hepatitis B virus coinfection in a United States cohort of hepatitis C virus-infected patients. Hepatology. 2014 Dec; 60(6):1871-8. PMID: 25065513.
    Citations: 21     Fields:    Translation:Humans
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.