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Leonardo Riella, Ph.D., M.D.

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Biography
2010 - 2012
Basic Science Fellowship Grant in Transplantation
2010
Annual Scientific Exchange Young Innovator Award
2011
Harvard medical School Excellence in Tutoring Award
2011
ASE Young Innovator Award
2012
Fellow of the American Society of Nephrology
2012
John P. Merrill Career Development Grant in Transplantation
2012 - 2017
National FTF Transition Award
2016
AST Basic Science Career Development Award

Overview

Featured Content

Bibliographic
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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  1. Danesh MJ, Mulvaney PM, Murakami N, Riella LV, Silk AW, Hanna GJ, Schmults CD. Impact of corticosteroids on allograft protection in renal transplant patients receiving anti-PD-1 immunotherapy. Cancer Immunol Immunother. 2020 Jun 25. PMID: 32588077.
    Citations:    
  2. de Oliveira PGFP, Bonfante EA, Bergamo ETP, de Souza SLS, Riella L, Torroni A, Benalcazar Jalkh EB, Witek L, Lopez CD, Zambuzzi WF, Coelho PG. Obesity/Metabolic Syndrome and Diabetes Mellitus on Peri-implantitis. Trends Endocrinol Metab. 2020 Jun 23. PMID: 32591106.
    Citations:    
  3. Angeletti A, Trivelli A, Magnasco A, Drovandi S, Sanguineri F, Santaniello M, Ferrando G, Forno R, Cipresso G, Tripodi G, Riella LV, Cravedi P, Ghiggeri GM. Risk of COVID-19 in young kidney transplant recipients. Results from a single-center observational study. Clin Transplant. 2020 May 12; e13889. PMID: 32396985.
    Citations:    
  4. Zaza G, Benedetti C, Fribourg M, Maggiore U, Azzi J, Riella LV, Cravedi P. SARS-CoV-2 pandemic and the need for transplant-oriented trials. Transpl Int. 2020 Apr 25. PMID: 32333712.
    Citations:    
  5. Kaminski MM, Alcantar MA, Lape IT, Greensmith R, Huske AC, Valeri JA, Marty FM, Klämbt V, Azzi J, Akalin E, Riella LV, Collins JJ. A CRISPR-based assay for the detection of opportunistic infections post-transplantation and for the monitoring of transplant rejection. Nat Biomed Eng. 2020 Jun; 4(6):601-609. PMID: 32284553.
    Citations:    
  6. Gandolfini I, Delsante M, Fiaccadori E, Zaza G, Manenti L, Degli Antoni A, Peruzzi L, Riella LV, Cravedi P, Maggiore U. COVID-19 in kidney transplant recipients. Am J Transplant. 2020 Jul; 20(7):1941-1943. PMID: 32233067.
    Citations:    
  7. Kollar B, Rizzo NM, Borges TJ, Haug V, Abdulrazzak O, Kauke M, Safi AF, Lian CG, Marty FM, Rutherford AE, Mitchell RN, Murphy GF, Tullius SG, Riella LV, Pomahac B. Accelerated chronic skin changes without allograft vasculopathy: A 10-year outcome report after face transplantation. Surgery. 2020 06; 167(6):991-998. PMID: 32113580.
    Citations:    
  8. Uffing A, Pérez-Sáez MJ, Mazzali M, Manfro RC, Bauer AC, de Sottomaior Drumond F, O'Shaughnessy MM, Cheng XS, Chin KK, Ventura CG, Agena F, David-Neto E, Mansur JB, Kirsztajn GM, Tedesco-Silva H, Neto GMV, Arias-Cabrales C, Buxeda A, Bugnazet M, Jouve T, Malvezzi P, Akalin E, Alani O, Agrawal N, La Manna G, Comai G, Bini C, Muhsin SA, Riella MC, Hokazono SR, Farouk SS, Haverly M, Mothi SS, Berger SP, Cravedi P, Riella LV. Recurrence of FSGS after Kidney Transplantation in Adults. Clin J Am Soc Nephrol. 2020 Feb 07; 15(2):247-256. PMID: 31974287.
    Citations:    
  9. Murakami N, Riella LV. Response by Murakami and Riella to Letter Regarding Article, "Notch-1 Inhibition Promoted Immune Regulation in Transplantation Via Regulatory T Cell-Dependent Mechanisms". Circulation. 2020 01 21; 141(3):e37-e38. PMID: 31958243.
    Citations:    
  10. Shubin AV, Kollar B, Dillon ST, Pomahac B, Libermann TA, Riella LV. Blood proteome profiling using aptamer-based technology for rejection biomarker discovery in transplantation. Sci Data. 2019 12 09; 6(1):314. PMID: 31819064.
    Citations:    
  11. Patel AB, Choi JY, Mutter WP, Weins A, Riella LV. Crystalline light chain proximal tubulopathy and podocytopathy: a case report. J Bras Nefrol. 2020 Mar; 42(1):99-105. PMID: 31799982.
    Citations:    
  12. Kollar B, Uffing A, Borges TJ, Shubin AV, Aoyama BT, Dagot C, Haug V, Kauke M, Safi AF, Talbot SG, Morelon E, Dakpe S, Pomahac B, Riella LV. MMP3 Is a Non-invasive Biomarker of Rejection in Skin-Bearing Vascularized Composite Allotransplantation: A Multicenter Validation Study. Front Immunol. 2019; 10:2771. PMID: 31849957.
    Citations:    
  13. Murakami N, Riella LV. Not transplanting kidney donors with acute kidney injury: a missed opportunity? J Bras Nefrol. 2019 Oct-Dec; 41(4):448-450. PMID: 31904762.
    Citations:    
  14. Leon J, Pérez-Sáez MJ, Batal I, Beck LH, Rennke HG, Canaud G, Legendre C, Pascual J, Riella LV. Membranous Nephropathy Posttransplantation: An Update of the Pathophysiology and Management. Transplantation. 2019 10; 103(10):1990-2002. PMID: 31568231.
    Citations:    
  15. Li GZ, Tio MC, Pak LM, Krier J, Seifter JL, Tullius SG, Riella LV, Malek SK, Stergachis AB. Noncirrhotic hyperammonemia after deceased donor kidney transplantation: A case report. Am J Transplant. 2019 11; 19(11):3197-3201. PMID: 31347272.
    Citations:    
  16. Magee CN, Murakami N, Borges TJ, Shimizu T, Safa K, Ohori S, Cai S, Uffing A, Azzi J, Elyaman W, Charbonnier LM, Liu K, Toprak D, Visner G, Chatila TA, Siebel CW, Najafian N, Riella LV. Notch-1 Inhibition Promotes Immune Regulation in Transplantation Via Regulatory T Cell-Dependent Mechanisms. Circulation. 2019 09 09; 140(10):846-863. PMID: 31266349.
    Citations:    
  17. Haug V, Kollar B, Obed D, Kiwanuka H, Turk M, Wo L, Tasigiorgos S, Kueckelhaus M, Riella LV, Pomahac B. The Evolving Clinical Presentation of Acute Rejection in Facial Transplantation. JAMA Facial Plast Surg. 2019 Jul 01; 21(4):278-285. PMID: 30998810.
    Citations:    
  18. Tasigiorgos S, Kollar B, Turk M, Perry B, Alhefzi M, Kiwanuka H, Nizzi MC, Marty FM, Chandraker A, Tullius SG, Riella LV, Pomahac B. Five-Year Follow-up after Face Transplantation. N Engl J Med. 2019 06 27; 380(26):2579-2581. PMID: 31141626.
    Citations:    
  19. Uffing A, Hidalgo LG, McMullan C, Perry J, Milford EL, Murakami N, Yeung MY, Guleria I, Wood IG, Akalin E, Azzi J, Chandraker AK, Riella LV. Preformed Donor-specific Antibodies Against HLA Class II and Graft Outcomes in Deceased-donor Kidney Transplantation. Transplant Direct. 2019 May; 5(5):e446. PMID: 31165081.
    Citations:    
  20. Leon J, Pérez-Sáez MJ, Batal I, Beck LH, Rennke HG, Canaud G, Legendre C, Pascual J, Riella LV. Membranous Nephropathy Post-Transplantation: An Update of the Pathophysiology and Management. Transplantation. 2019 Apr 10. PMID: 30985736.
    Citations:    
  21. Chong AS, Rothstein DM, Safa K, Riella LV. Outstanding questions in transplantation: B cells, alloantibodies, and humoral rejection. Am J Transplant. 2019 08; 19(8):2155-2163. PMID: 30803121.
    Citations:    
  22. Riella C, Siemens TA, Wang M, Campos RP, Moraes TP, Riella LV, Friedman DJ, Riella MC, Pollak MR. APOL1-Associated Kidney Disease in Brazil. Kidney Int Rep. 2019 Jul; 4(7):923-929. PMID: 31317114.
    Citations:    
  23. Kollar B, Pomahac B, Riella LV. Novel immunological and clinical insights in vascularized composite allotransplantation. Curr Opin Organ Transplant. 2019 02; 24(1):42-48. PMID: 30531538.
    Citations:    Fields:    
  24. Pérez-Sáez MJ, Yu B, Uffing A, Murakami N, Borges TJ, Azzi J, El Haji S, Gabardi S, Riella LV. Conversion from tacrolimus to belatacept improves renal function in kidney transplant patients with chronic vascular lesions in allograft biopsy. Clin Kidney J. 2019 Aug; 12(4):586-591. PMID: 31384452.
    Citations:    
  25. Krezdorn N, Lian CG, Wells M, Wo L, Tasigiorgos S, Xu S, Borges TJ, Frierson RM, Stanek E, Riella LV, Pomahac B, Murphy GF. Chronic rejection of human face allografts. Am J Transplant. 2019 04; 19(4):1168-1177. PMID: 30312535.
    Citations:    Fields:    
  26. Kollar B, Shubin A, Borges TJ, Tasigiorgos S, Win TS, Lian CG, Dillon ST, Gu X, Wyrobnik I, Murphy GF, Pomahac B, Libermann TA, Riella LV. Increased levels of circulating MMP3 correlate with severe rejection in face transplantation. Sci Rep. 2018 10 08; 8(1):14915. PMID: 30297859.
    Citations:    Fields:    
  27. Uffing A, Pérez-Sáez MJ, La Manna G, Comai G, Fischman C, Farouk S, Manfro RC, Bauer AC, Lichtenfels B, Mansur JB, Tedesco-Silva H, Kirsztajn GM, Manonelles A, Bestard O, Riella MC, Hokazono SR, Arias-Cabrales C, David-Neto E, Ventura CG, Akalin E, Mohammed O, Khankin EV, Safa K, Malvezzi P, O'Shaughnessy MM, Cheng XS, Cravedi P, Riella LV. A large, international study on post-transplant glomerular diseases: the TANGO project. BMC Nephrol. 2018 09 12; 19(1):229. PMID: 30208881.
    Citations:    Fields:    
  28. Borges TJ, Murakami N, Machado FD, Murshid A, Lang BJ, Lopes RL, Bellan LM, Uehara M, Antunes KH, Pérez-Saéz MJ, Birrane G, Vianna P, Gonçalves JIB, Zanin RF, Azzi J, Abdi R, Ishido S, Shin JS, Souza APD, Calderwood SK, Riella LV, Bonorino C. March1-dependent modulation of donor MHC II on CD103+ dendritic cells mitigates alloimmunity. Nat Commun. 2018 08 28; 9(1):3482. PMID: 30154416.
    Citations:    Fields:    Translation:AnimalsCells
  29. Riella LV. Understanding the causes of mortality post-transplantation - there is more than meets the eye. J Bras Nefrol. 2018 Apr-Jun; 40(2):102-104. PMID: 29944155.
    Citations:    Fields:    
  30. Krezdorn N, Tasigiorgos S, Wo L, Lopdrup R, Turk M, Kiwanuka H, Ahmed S, Petruzzo P, Bueno E, Pomahac B, Riella LV. Kidney Dysfunction After Vascularized Composite Allotransplantation. Transplant Direct. 2018 Jul; 4(7):e362. PMID: 30046652.
    Citations:    
  31. Leon J, Pérez-Sáez MJ, Uffing A, Murakami N, Watanabe A, Cureton P, Kenyon V, Keating L, Yee K, Fernandes Satiro CA, Yu B, Bonventre JV, Fasano A, Riella LV. Effect of Combined Gluten-Free, Dairy-Free Diet in Children With Steroid-Resistant Nephrotic Syndrome: An Open Pilot Trial. Kidney Int Rep. 2018 Jul; 3(4):851-860. PMID: 30116795.
    Citations:    
  32. Fallahian F, Molway D, Jadeja S, Clark R, Marty FM, Riella LV, Chandraker A, Talbot SG. Eponychial lesions following bilateral upper extremity vascular composite allotransplantation: a case report. Case Reports Plast Surg Hand Surg. 2018; 5(1):14-17. PMID: 29441355.
    Citations:    
  33. Riella LV, Alegre ML. Novel Role of Calcineurin Inhibitors in Curbing T Cells' Sweet Tooth. Am J Transplant. 2018 Jan; 18(1):3. PMID: 29267999.
    Citations:    Fields:    
  34. Sula Karreci E, Eskandari SK, Dotiwala F, Routray SK, Kurdi AT, Assaker JP, Luckyanchykov P, Mihali AB, Maarouf O, Borges TJ, Alkhudhayri A, Patel KR, Radwan A, Ghobrial I, McGrath M, Chandraker A, Riella LV, Elyaman W, Abdi R, Lieberman J, Azzi J. Human regulatory T cells undergo self-inflicted damage via granzyme pathways upon activation. JCI Insight. 2017 11 02; 2(21). PMID: 29093262.
    Citations:    Fields:    
  35. Sprangers B, Nair V, Launay-Vacher V, Riella LV, Jhaveri KD. Risk factors associated with post-kidney transplant malignancies: an article from the Cancer-Kidney International Network. Clin Kidney J. 2018 Jun; 11(3):315-329. PMID: 29942495.
    Citations:    
  36. Park J, Lin HY, Assaker JP, Jeong S, Huang CH, Kurdi T, Lee K, Fraser K, Min C, Eskandari S, Routray S, Tannous B, Abdi R, Riella L, Chandraker A, Castro CM, Weissleder R, Lee H, Azzi JR. Integrated Kidney Exosome Analysis for the Detection of Kidney Transplant Rejection. ACS Nano. 2017 11 28; 11(11):11041-11046. PMID: 29053921.
    Citations: 2     Fields:    Translation:HumansCells
  37. Azzi J, Raimondi G, Mas V, Riella LV, Elfadawy N, Safa K, Wojciechowski D, Kanak M, Nog R, Maltzman JS, Ford ML, Pober JS, Luo XR, Rothstein D, Miller ML, Matthews D, Burlingham W, Levings M, Heeger P, Higdon L, Gill J, Gill RG, Alegre ML. The outstanding questions in transplantation: It's about time…. Am J Transplant. 2018 01; 18(1):271-272. PMID: 28758364.
    Citations:    Fields:    
  38. Win TS, Murakami N, Borges TJ, Chandraker A, Murphy G, Lian C, Barrera V, Ho Sui S, Schoenfeld D, Teague J, Bueno E, Tullius SG, Pomahac B, Clark RA, Riella LV. Longitudinal immunological characterization of the first presensitized recipient of a face transplant. JCI Insight. 2017 Jul 06; 2(13). PMID: 28679959.
    Citations:    Fields:    
  39. Madariaga HM, Riella LV. Chronic Allograft Injury: An Overview of Pathogenesis and Treatment Strategies. Contrib Nephrol. 2017; 190:168-180. PMID: 28535528.
    Citations:    Fields:    Translation:Humans
  40. Riella LV, Bagley J, Iacomini J, Alegre ML. Impact of environmental factors on alloimmunity and transplant fate. J Clin Invest. 2017 Jun 30; 127(7):2482-2491. PMID: 28481225.
    Citations: 1     Fields:    Translation:HumansAnimalsCells
  41. Kueckelhaus M, Dermietzel A, Alhefzi M, Aycart MA, Fischer S, Krezdorn N, Wo L, Maarouf OH, Riella LV, Abdi R, Bueno EM, Pomahac B. Acellular Hypothermic Extracorporeal Perfusion Extends Allowable Ischemia Time in a Porcine Whole Limb Replantation Model. Plast Reconstr Surg. 2017 Apr; 139(4):922e-932e. PMID: 28350667.
    Citations: 1     Fields:    Translation:Animals
  42. Siddiqui Z, Tedesco-Silva H, Riella LV. Belatacept in kidney transplantation - past and future perspectives. J Bras Nefrol. 2017 Apr-Jun; 39(2):205-212. PMID: 29069245.
    Citations:    Fields:    Translation:Humans
  43. Mendu ML, Ciociolo GR, McLaughlin SR, Graham DA, Ghazinouri R, Parmar S, Grossier A, Rosen R, Laskowski KR, Riella LV, Robinson ES, Charytan DM, Bonventre JV, Greenberg JO, Waikar SS. A Decision-Making Algorithm for Initiation and Discontinuation of RRT in Severe AKI. Clin J Am Soc Nephrol. 2017 02 07; 12(2):228-236. PMID: 28119408.
    Citations: 5     Fields:    Translation:Humans
  44. Murakami N, Motwani S, Riella LV. Renal complications of immune checkpoint blockade. Curr Probl Cancer. 2017 Mar - Apr; 41(2):100-110. PMID: 28189263.
    Citations: 6     Fields:    Translation:HumansAnimals
  45. Sula Karreci E, Fan H, Uehara M, Mihali AB, Singh PK, Kurdi AT, Solhjou Z, Riella LV, Ghobrial I, Laragione T, Routray S, Assaker JP, Wang R, Sukenick G, Shi L, Barrat FJ, Nathan CF, Lin G, Azzi J. Brief treatment with a highly selective immunoproteasome inhibitor promotes long-term cardiac allograft acceptance in mice. Proc Natl Acad Sci U S A. 2016 12 27; 113(52):E8425-E8432. PMID: 27956634.
    Citations: 4     Fields:    Translation:HumansAnimalsCells
  46. Cardarelli F, Bijol V, Chandraker A, Varga C, Riella LV. Acute myeloid leukemia after kidney transplantation: a case report and literature review. J Bras Nefrol. 2016 Dec; 38(4):455-461. PMID: 28001189.
    Citations:    Fields:    Translation:Humans
  47. Borges TJ, Murakami N, Riella LV. Current status of alloimmunity. Curr Opin Nephrol Hypertens. 2016 11; 25(6):556-562. PMID: 27584931.
    Citations:    Fields:    Translation:Humans
  48. Riella LV, Djamali A, Pascual J. Chronic allograft injury: Mechanisms and potential treatment targets. Transplant Rev (Orlando). 2017 01; 31(1):1-9. PMID: 27847221.
    Citations: 4     Fields:    Translation:Humans
  49. Murakami N, Maillard I, Riella LV. Notch Signaling and Immune Regulation in Alloimmunity. Curr Transplant Rep. 2016 Dec; 3(4):294-302. PMID: 29977738.
    Citations:    
  50. Camirand G, Riella LV. Treg-Centric View of Immunosuppressive Drugs in Transplantation: A Balancing Act. Am J Transplant. 2017 03; 17(3):601-610. PMID: 27581661.
    Citations: 2     Fields:    Translation:HumansAnimalsCells
  51. Krezdorn N, Murakami N, Pomahac B, Riella LV. Immunological Characteristics of a Patient With Belatacept-Resistant Acute Rejection After Face Transplantation. Am J Transplant. 2016 11; 16(11):3305-3307. PMID: 27457067.
    Citations: 1     Fields:    Translation:HumansCells
  52. Lin MV, Sise ME, Pavlakis M, Amundsen BM, Chute D, Rutherford AE, Chung RT, Curry MP, Hanifi JM, Gabardi S, Chandraker A, Heher EC, Elias N, Riella LV. Efficacy and Safety of Direct Acting Antivirals in Kidney Transplant Recipients with Chronic Hepatitis C Virus Infection. PLoS One. 2016; 11(7):e0158431. PMID: 27415632.
    Citations: 12     Fields:    Translation:Humans
  53. Laws LH, Parker CE, Cherala G, Koguchi Y, Waisman A, Slifka MK, Oberbarnscheidt MH, Obhrai JS, Yeung MY, Riella LV. Inflammation Causes Resistance to Anti-CD20-Mediated B Cell Depletion. Am J Transplant. 2016 11; 16(11):3139-3149. PMID: 27265023.
    Citations: 1     Fields:    Translation:AnimalsCells
  54. Riella LV, Gabardi S, Azzi J. Belatacept and Long-Term Outcomes in Kidney Transplantation. N Engl J Med. 2016 06 30; 374(26):2599-600. PMID: 27355545.
    Citations: 1     Fields:    Translation:Humans
  55. Murakami N, Borges TJ, Yamashita M, Riella LV. Erratum: Severe acute interstitial nephritis after combination immune-checkpoint inhibitor therapy for metastatic melanoma. Clin Kidney J. 2016 Aug; 9(4):649. PMID: 27478613.
    Citations:    
  56. Bittencourt MS, Riella LV. Coronary artery calcium density for the prediction of mortality in CKD patients: One size does not fit all. Atherosclerosis. 2016 07; 250:180-2. PMID: 27180644.
    Citations:    Fields:    Translation:Humans
  57. Chung J, Riella LV, Maillard I. Targeting the Notch Pathway to Prevent Rejection. Am J Transplant. 2016 11; 16(11):3079-3085. PMID: 27037759.
    Citations: 2     Fields:    Translation:HumansAnimalsCells
  58. Murakami N, Borges TJ, Yamashita M, Riella LV. Severe acute interstitial nephritis after combination immune-checkpoint inhibitor therapy for metastatic melanoma. Clin Kidney J. 2016 Jun; 9(3):411-7. PMID: 27274826.
    Citations: 9     
  59. Borges TJ, O'Malley JT, Wo L, Murakami N, Smith B, Azzi J, Tripathi S, Lane JD, Bueno EM, Clark RA, Tullius SG, Chandraker A, Lian CG, Murphy GF, Strom TB, Pomahac B, Najafian N, Riella LV. Codominant Role of Interferon-?- and Interleukin-17-Producing T Cells During Rejection in Full Facial Transplant Recipients. Am J Transplant. 2016 07; 16(7):2158-71. PMID: 26749226.
    Citations: 4     Fields:    Translation:HumansCells
  60. Riella LV. Digital Learning in Transplantation. Transplantation. 2016 Apr; 100(4):701-2. PMID: 26998849.
    Citations:    Fields:    Translation:Humans
  61. Murakami N, Riella LV. CD4+ CD28-Negative Cells: Armed and Dangerous. Am J Transplant. 2016 Apr; 16(4):1045-6. PMID: 26613671.
    Citations: 1     Fields:    Translation:HumansCells
  62. Magee CN, Riella LV. Notch and its ligands in alloimmunity and rejection. Curr Opin Organ Transplant. 2016 Feb; 21(1):15-21. PMID: 26626420.
    Citations: 2     Fields:    Translation:HumansAnimalsCells
  63. Hod T, Riella LV, Chandraker A. Recombinant PTH therapy for severe hypoparathyroidism after kidney transplantation in pre-transplant parathyroidectomized patients: review of the literature and a case report. Clin Transplant. 2015 Nov; 29(11):951-7. PMID: 26331695.
    Citations: 1     Fields:    Translation:Humans
  64. Riella LV, Sheridan AM. Testing for High-Risk APOL1 Alleles in Potential Living Kidney Donors. Am J Kidney Dis. 2015 Sep; 66(3):396-401. PMID: 26049628.
    Citations: 11     Fields:    Translation:Humans
  65. Safa K, Ohori S, Borges TJ, Uehara M, Batal I, Shimizu T, Magee CN, Belizaire R, Abdi R, Wu C, Chandraker A, Riella LV. Salt Accelerates Allograft Rejection through Serum- and Glucocorticoid-Regulated Kinase-1-Dependent Inhibition of Regulatory T Cells. J Am Soc Nephrol. 2015 Oct; 26(10):2341-7. PMID: 25833841.
    Citations: 10     Fields:    Translation:AnimalsCells
  66. Bittencourt MS, Hulten EA, Ghoshhajra B, Abbara S, Murthy VL, Divakaran S, Nasir K, Gowdak LH, Riella LV, Chiumiento M, Hoffmann U, Di Carli MF, Blankstein R. Incremental prognostic value of kidney function decline over coronary artery disease for cardiovascular event prediction after coronary computed tomography. Kidney Int. 2015 Jul; 88(1):152-9. PMID: 25629550.
    Citations: 1     Fields:    Translation:Humans
  67. Fischer S, Lian CG, Kueckelhaus M, Strom TB, Edelman ER, Clark RA, Murphy GF, Chandraker AK, Riella LV, Tullius SG, Pomahac B. Acute rejection in vascularized composite allotransplantation. Curr Opin Organ Transplant. 2014 Dec; 19(6):531-44. PMID: 25333831.
    Citations: 10     Fields:    Translation:HumansAnimals
  68. Allegretti AS, Yeung MY, Riella LV. Counseling potential donors to the risk of ESRD after kidney donation: glass half-full or half-empty? Am J Transplant. 2014 Oct; 14(10):2434-5. PMID: 25167951.
    Citations:    Fields:    Translation:Humans
  69. Murakami N, Riella LV, Funakoshi T. Risk of metabolic complications in kidney transplantation after conversion to mTOR inhibitor: a systematic review and meta-analysis. Am J Transplant. 2014 Oct; 14(10):2317-27. PMID: 25146383.
    Citations: 16     Fields:    Translation:Humans
  70. Grafals M, Smith B, Murakami N, Trabucco A, Hamill K, Marangos E, Gilligan H, Pomfret EA, Pomposelli JJ, Simpson MA, Azzi J, Najafian N, Riella LV. Immunophenotyping and efficacy of low dose ATG in non-sensitized kidney recipients undergoing early steroid withdrawal: a randomized pilot study. PLoS One. 2014; 9(8):e104408. PMID: 25111080.
    Citations: 6     Fields:    Translation:HumansAnimalsCells
  71. Murakami N, Riella LV. Co-inhibitory pathways and their importance in immune regulation. Transplantation. 2014 Jul 15; 98(1):3-14. PMID: 24978034.
    Citations: 15     Fields:    Translation:HumansAnimalsCells
  72. Riella LV, Safa K, Yagan J, Lee B, Azzi J, Najafian N, Abdi R, Milford E, Mah H, Gabardi S, Malek S, Tullius SG, Magee C, Chandraker A. Long-term outcomes of kidney transplantation across a positive complement-dependent cytotoxicity crossmatch. Transplantation. 2014 Jun 27; 97(12):1247-52. PMID: 24854670.
    Citations: 7     Fields:    Translation:Humans
  73. Safa K, Riella LV, Chandraker A. Beyond calcineurin inhibitors: emerging agents in kidney transplantation. Curr Opin Nephrol Hypertens. 2013 Nov; 22(6):689-97. PMID: 24100221.
    Citations: 4     Fields:    Translation:HumansCells
  74. Riella LV, Sayegh MH. T-cell co-stimulatory blockade in transplantation: two steps forward one step back! Expert Opin Biol Ther. 2013 Nov; 13(11):1557-68. PMID: 24083381.
    Citations: 8     Fields:    Translation:HumansAnimalsCells
  75. Azzi J, Skartsis N, Mounayar M, Magee CN, Batal I, Ting C, Moore R, Riella LV, Ohori S, Abdoli R, Smith B, Fiorina P, Heathcote D, Bakhos T, Ashton-Rickardt PG, Abdi R. Serine protease inhibitor 6 plays a critical role in protecting murine granzyme B-producing regulatory T cells. J Immunol. 2013 Sep 01; 191(5):2319-27. PMID: 23913965.
    Citations: 10     Fields:    Translation:AnimalsCells
  76. Riella LV, Yang J, Chock S, Safa K, Magee CN, Vanguri V, Elyaman W, Lahoud Y, Yagita H, Abdi R, Najafian N, Medina-Pestana JO, Chandraker A. Jagged2-signaling promotes IL-6-dependent transplant rejection. Eur J Immunol. 2013 Jun; 43(6):1449-58. PMID: 23526606.
    Citations: 10     Fields:    Translation:AnimalsCells
  77. Riella LV, Dada S, Chabtini L, Smith B, Huang L, Dakle P, Mfarrej B, D'Addio F, Adams LT, Kochupurakkal N, Vergani A, Fiorina P, Mellor AL, Sharpe AH, Yagita H, Guleria I. B7h (ICOS-L) maintains tolerance at the fetomaternal interface. Am J Pathol. 2013 Jun; 182(6):2204-13. PMID: 23578385.
    Citations: 10     Fields:    Translation:AnimalsCells
  78. Batal I, Bijol V, Riella LV, Rennke HG. Fever, dysuria and elevated serum creatinine in a kidney transplant recipient. Am J Transplant. 2013 Mar; 13(3):817-8. PMID: 23437883.
    Citations:    Fields:    Translation:Humans
  79. Riella L, Bromberg JS. LITERATURE Watch: implications for transplantation. Am J Transplant. 2013 Jan; 13(1):3. PMID: 23279677.
    Citations:    Fields:    
  80. Riella LV, Paterson AM, Sharpe AH, Chandraker A. Role of the PD-1 pathway in the immune response. Am J Transplant. 2012 Oct; 12(10):2575-87. PMID: 22900886.
    Citations: 70     Fields:    Translation:HumansCells
  81. Riella LV, Chandraker A. Stem cell therapy in kidney transplantation. JAMA. 2012 Jul 11; 308(2):130; author reply 130-1. PMID: 22782400.
    Citations: 5     Fields:    Translation:Humans
  82. Riella LV, Gabardi S, Chandraker A. Dyslipidemia and its therapeutic challenges in renal transplantation. Am J Transplant. 2012 Aug; 12(8):1975-82. PMID: 22578270.
    Citations: 11     Fields:    Translation:Humans
  83. De Serres SA, Mfarrej BG, Grafals M, Riella LV, Magee CN, Yeung MY, Dyer C, Ahmad U, Chandraker A, Najafian N. Derivation and validation of a cytokine-based assay to screen for acute rejection in renal transplant recipients. Clin J Am Soc Nephrol. 2012 Jun; 7(6):1018-25. PMID: 22498498.
    Citations: 5     Fields:    Translation:HumansCells
  84. Riella LV, Liu T, Yang J, Chock S, Shimizu T, Mfarrej B, Batal I, Xiao X, Sayegh MH, Chandraker A. Deleterious effect of CTLA4-Ig on a Treg-dependent transplant model. Am J Transplant. 2012 Apr; 12(4):846-55. PMID: 22300534.
    Citations: 40     Fields:    Translation:AnimalsCells
  85. D'Addio F, Riella LV, Mfarrej BG, Chabtini L, Adams LT, Yeung M, Yagita H, Azuma M, Sayegh MH, Guleria I. The link between the PDL1 costimulatory pathway and Th17 in fetomaternal tolerance. J Immunol. 2011 Nov 01; 187(9):4530-41. PMID: 21949023.
    Citations: 36     Fields:    Translation:AnimalsCells
  86. Riella LV, Ueno T, Batal I, De Serres SA, Bassil R, Elyaman W, Yagita H, Medina-Pestana JO, Chandraker A, Najafian N. Blockade of Notch ligand d1 promotes allograft survival by inhibiting alloreactive Th1 cells and cytotoxic T cell generation. J Immunol. 2011 Nov 01; 187(9):4629-38. PMID: 21949024.
    Citations: 10     Fields:    Translation:AnimalsCells
  87. Bassil R, Zhu B, Lahoud Y, Riella LV, Yagita H, Elyaman W, Khoury SJ. Notch ligand delta-like 4 blockade alleviates experimental autoimmune encephalomyelitis by promoting regulatory T cell development. J Immunol. 2011 Sep 01; 187(5):2322-8. PMID: 21813770.
    Citations: 24     Fields:    Translation:AnimalsCells
  88. Riella LV, Sayegh MH. T-cell co-stimulatory blockade in kidney transplantation: back to the bench. Kidney Int Suppl (2011). 2011 Aug; 1(2):25-30. PMID: 25018899.
    Citations: 2     
  89. Batal I, Azzi J, El-Haddad N, Riella LV, Lunz JG, Zeevi A, Sasatomi E, Basu A, Tan H, Shapiro R, Randhawa P. Immunohistochemical markers of tissue injury in biopsies with transplant glomerulitis. Hum Pathol. 2012 Jan; 43(1):69-80. PMID: 21777946.
    Citations: 3     Fields:    Translation:Humans
  90. Yang J, Riella LV, Chock S, Liu T, Zhao X, Yuan X, Paterson AM, Watanabe T, Vanguri V, Yagita H, Azuma M, Blazar BR, Freeman GJ, Rodig SJ, Sharpe AH, Chandraker A, Sayegh MH. The novel costimulatory programmed death ligand 1/B7.1 pathway is functional in inhibiting alloimmune responses in vivo. J Immunol. 2011 Aug 01; 187(3):1113-9. PMID: 21697455.
    Citations: 42     Fields:    Translation:AnimalsCells
  91. Paterson AM, Brown KE, Keir ME, Vanguri VK, Riella LV, Chandraker A, Sayegh MH, Blazar BR, Freeman GJ, Sharpe AH. The programmed death-1 ligand 1:B7-1 pathway restrains diabetogenic effector T cells in vivo. J Immunol. 2011 Aug 01; 187(3):1097-105. PMID: 21697456.
    Citations: 49     Fields:    Translation:AnimalsCells
  92. Riella LV, Watanabe T, Sage PT, Yang J, Yeung M, Azzi J, Vanguri V, Chandraker A, Sharpe AH, Sayegh MH, Najafian N. Essential role of PDL1 expression on nonhematopoietic donor cells in acquired tolerance to vascularized cardiac allografts. Am J Transplant. 2011 Apr; 11(4):832-40. PMID: 21401869.
    Citations: 10     Fields:    Translation:AnimalsCells
  93. Riella LV, Rennke HG, Grafals M, Chandraker A. Hypophosphatemia in kidney transplant recipients: report of acute phosphate nephropathy as a complication of therapy. Am J Kidney Dis. 2011 Apr; 57(4):641-5. PMID: 21333424.
    Citations: 3     Fields:    Translation:Humans
  94. Bedi DS, Riella LV, Tullius SG, Chandraker A. Animal models of chronic allograft injury: contributions and limitations to understanding the mechanism of long-term graft dysfunction. Transplantation. 2010 Nov 15; 90(9):935-44. PMID: 20703180.
    Citations: 5     Fields:    Translation:HumansAnimals
  95. Yang J, Riella LV, Boenisch O, Popoola J, Robles S, Watanabe T, Vanguri V, Yuan X, Guleria I, Turka LA, Sayegh MH, Chandraker A. Paradoxical functions of B7: CD28 costimulation in a MHC class II-mismatched cardiac transplant model. Am J Transplant. 2009 Dec; 9(12):2837-44. PMID: 19845593.
    Citations: 12     Fields:    Translation:AnimalsCells
  96. Riella LV, Golla S, Dogaru G, Rennke HG, Christopher K. Renal cortical necrosis complicating laundry detergent ingestion. NDT Plus. 2009 Feb; 2(1):40-2. PMID: 25949283.
    Citations:    
  97. Surana SP, Riella LV, Keithi-Reddy SR, Charytan DM, Singh AK. Acute coronary syndrome in ESRD patients. Kidney Int. 2009 Mar; 75(5):558-62. PMID: 18509314.
    Citations: 3     Fields:    Translation:Humans
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.