Harvard Catalyst Profiles

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Karan Joshua Abraham, M.D.

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Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Patel PS, Abraham KJ, Guturi KKN, Halaby MJ, Khan Z, Palomero L, Ho B, Duan S, St-Germain J, Algouneh A, Mateo F, El Ghamrasni S, Barbour H, Barnes DR, Beesley J, Sanchez O, Berman HK, Brown GW, Affar EB, Chenevix-Trench G, Antoniou AC, Arrowsmith CH, Raught B, Pujana MA, Mekhail K, Hakem A, Hakem R. RNF168 regulates R-loop resolution and genomic stability in BRCA1/2-deficient tumors. J Clin Invest. 2021 02 01; 131(3). PMID: 33529165.
    Citations: 3     Fields:    
  2. Abraham KJ, Khosraviani N, Chan JNY, Gorthi A, Samman A, Zhao DY, Wang M, Bokros M, Vidya E, Ostrowski LA, Oshidari R, Pietrobon V, Patel PS, Algouneh A, Singhania R, Liu Y, Yerlici VT, De Carvalho DD, Ohh M, Dickson BC, Hakem R, Greenblatt JF, Lee S, Bishop AJR, Mekhail K. Nucleolar RNA polymerase II drives ribosome biogenesis. Nature. 2020 09; 585(7824):298-302. PMID: 32669707.
    Citations: 19     Fields:    Translation:HumansCells
  3. Abraham KJ, Casey J, Subotic A, Tarzi C, Zhu A, Cusimano MD. Medical assessment of potential concussion in elite football: video analysis of the 2016 UEFA European championship. BMJ Open. 2019 05 30; 9(5):e024607. PMID: 31147360.
    Citations: 3     Fields:    Translation:Humans
  4. Ostrowski LA, Hall AC, Szafranski KJ, Oshidari R, Abraham KJ, Chan JNY, Krustev C, Zhang K, Wang A, Liu Y, Guo R, Mekhail K. Conserved Pbp1/Ataxin-2 regulates retrotransposon activity and connects polyglutamine expansion-driven protein aggregation to lifespan-controlling rDNA repeats. Commun Biol. 2018; 1:187. PMID: 30417124.
    Citations: 4     
  5. Abraham KJ. On mindset, mental preparation and chasing breakthroughs: A physician-scientist trainee's perspective. Clin Invest Med. 2018 11 03; 41:11-13. PMID: 30394272.
    Citations:    Fields:    Translation:Humans
  6. Oshidari R, Strecker J, Chung DKC, Abraham KJ, Chan JNY, Damaren CJ, Mekhail K. Nuclear microtubule filaments mediate non-linear directional motion of chromatin and promote DNA repair. Nat Commun. 2018 07 02; 9(1):2567. PMID: 29967403.
    Citations: 18     Fields:    Translation:AnimalsCells
  7. Zhou TE, Barton KI, Cook E, Benesch MGK, Jette N, Moderie C, Ondrusova K, Lees C, Steadman PE, Marvasti TB, Mirali S, Liu PJ, Babadagli EM, Abraham KJ, Zaslavsky KJ. Scientific Overview on CSCI-CITAC Annual General Meeting and 2016 Young Investigators' Forum. Clin Invest Med. 2017 10 19; 40(5):E211-E217. PMID: 29061226.
    Citations:    Fields:    Translation:Humans
  8. Lau A, Bourkas M, Lu YQQ, Ostrowski LA, Weber-Adrian D, Figueiredo C, Arshad H, Shoaei SZS, Morrone CD, Matan-Lithwick S, Abraham KJ, Wang H, Schmitt-Ulms G. Functional Amyloids and their Possible Influence on Alzheimer Disease. Discoveries (Craiova). 2017 Oct 16; 5(4):e79. PMID: 32309597.
    Citations:    
  9. Abraham KJ, Chan JN, Salvi JS, Ho B, Hall A, Vidya E, Guo R, Killackey SA, Liu N, Lee JE, Brown GW, Mekhail K. Intersection of calorie restriction and magnesium in the suppression of genome-destabilizing RNA-DNA hybrids. Nucleic Acids Res. 2016 Oct 14; 44(18):8870-8884. PMID: 27574117.
    Citations: 12     Fields:    Translation:HumansAnimalsCells
  10. Abraham KJ, Ostrowski LA, Mekhail K. Non-Coding RNA Molecules Connect Calorie Restriction and Lifespan. J Mol Biol. 2017 10 27; 429(21):3196-3214. PMID: 27561708.
    Citations: 5     Fields:    Translation:HumansAnimals
  11. Chung DK, Chan JN, Strecker J, Zhang W, Ebrahimi-Ardebili S, Lu T, Abraham KJ, Durocher D, Mekhail K. Perinuclear tethers license telomeric DSBs for a broad kinesin- and NPC-dependent DNA repair process. Nat Commun. 2015 Jul 24; 6:7742. PMID: 26205667.
    Citations: 34     Fields:    Translation:AnimalsCells
  12. Szafranski K, Abraham KJ, Mekhail K. Non-coding RNA in neural function, disease, and aging. Front Genet. 2015; 6:87. PMID: 25806046.
    Citations: 30     
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.