Harvard Catalyst Profiles

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Amy Jordan Wisdom, M.D.

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UCLA, Los Angeles, CABS05/2013Neuroscience
Duke University School of Medicine, Durham, NCMD, PhD05/2021MD/PhD
Cambridge Health Alliance, Cambridge, MA06/2022Internship
Harvard Radiation Oncology Program, Boston, MAResidency

The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
  1. F30CA221268 (WISDOM, AMY JORDAN) Jul 1, 2017 - Jun 30, 2021
    Dissecting the role of the immune system in the radiation response of Kras-mutant tumors
    Role: Principal Investigator

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Borchmann S, Selenz C, Lohmann M, Ludwig H, Gassa A, Brägelmann J, Lohneis P, Meder L, Mattlener J, Breid S, Nill M, Fassunke J, Wisdom AJ, Compes A, Gathof B, Alakus H, Kirsch D, Hekmat K, Büttner R, Reinhardt HC, Hallek M, Ullrich RT. Tripartite antigen-agnostic combination immunotherapy cures established poorly immunogenic tumors. J Immunother Cancer. 2022 10; 10(10). PMID: 36223955; PMCID: PMC9562723.
    Citations:    Fields:    Translation:Animals
  2. Wisdom AJ, Mowery YM, Hong CS, Himes JE, Nabet BY, Qin X, Zhang D, Chen L, Fradin H, Patel R, Bassil AM, Muise ES, King DA, Xu ES, Carpenter DJ, Kent CL, Smythe KS, Williams NT, Luo L, Ma Y, Alizadeh AA, Owzar K, Diehn M, Bradley T, Kirsch DG. Single cell analysis reveals distinct immune landscapes in transplant and primary sarcomas that determine response or resistance to immunotherapy. Nat Commun. 2020 12 17; 11(1):6410. PMID: 33335088; PMCID: PMC7746723.
    Citations: 18     Fields:    Translation:HumansAnimalsCells
  3. Wisdom AJ, Kirsch DG. Dissecting the Functional Significance of DNA Polymerase Mutations in Cancer. Cancer Res. 2020 12 15; 80(24):5459-5461. PMID: 33323408.
    Citations:    Fields:    Translation:Animals
  4. Wisdom AJ, Hong CS, Lin AJ, Xiang Y, Cooper DE, Zhang J, Xu ES, Kuo HC, Mowery YM, Carpenter DJ, Kadakia KT, Himes JE, Luo L, Ma Y, Williams N, Cardona DM, Haldar M, Diao Y, Markovina S, Schwarz JK, Kirsch DG. Neutrophils promote tumor resistance to radiation therapy. Proc Natl Acad Sci U S A. 2019 09 10; 116(37):18584-18589. PMID: 31462499; PMCID: PMC6744874.
    Citations: 37     Fields:    Translation:HumansAnimalsCells
  5. Lee CL, Mowery YM, Daniel AR, Zhang D, Sibley AB, Delaney JR, Wisdom AJ, Qin X, Wang X, Caraballo I, Gresham J, Luo L, Van Mater D, Owzar K, Kirsch DG. Mutational landscape in genetically engineered, carcinogen-induced, and radiation-induced mouse sarcoma. JCI Insight. 2019 07 11; 4(13). PMID: 31112524.
    Citations: 18     Fields:    Translation:HumansAnimals
  6. Mowery YM, Patel K, Chowdhary M, Rushing CN, Roy Choudhury K, Lowe JR, Olson AC, Wisdom AJ, Salama JK, Hanks BA, Khan MK, Salama AKS. Retrospective analysis of safety and efficacy of anti-PD-1 therapy and radiation therapy in advanced melanoma: A bi-institutional study. Radiother Oncol. 2019 09; 138:114-120. PMID: 31252292.
    Citations: 5     Fields:    Translation:Humans
  7. Wisdom AJ, Kirsch DG. Functional assay to guide precision radiotherapy by assessing individual patient radiosensitivity. EBioMedicine. 2019 Mar; 41:26-27. PMID: 30852160; PMCID: PMC6443667.
    Citations:    Fields:    Translation:Humans
  8. Wisdom AJ, Mowery YM, Riedel RF, Kirsch DG. Rationale and emerging strategies for immune checkpoint blockade in soft tissue sarcoma. Cancer. 2018 10 01; 124(19):3819-3829. PMID: 29723407; PMCID: PMC6215523.
    Citations: 17     Fields:    Translation:Humans
  9. Carpenter DJ, Mowery YM, Broadwater G, Rodrigues A, Wisdom AJ, Dorth JA, Patel PR, Shortell CK, Clough R, Brizel DM. The risk of carotid stenosis in head and neck cancer patients after radiation therapy. Oral Oncol. 2018 05; 80:9-15. PMID: 29706194; PMCID: PMC6827433.
    Citations: 13     Fields:    Translation:Humans
  10. Brownstein JM, Wisdom AJ, Castle KD, Mowery YM, Guida P, Lee CL, Tommasino F, Tessa C, Scifoni E, Gao J, Luo L, Campos LDS, Ma Y, Williams N, Jung SH, Durante M, Kirsch DG. Characterizing the Potency and Impact of Carbon Ion Therapy in a Primary Mouse Model of Soft Tissue Sarcoma. Mol Cancer Ther. 2018 04; 17(4):858-868. PMID: 29437879; PMCID: PMC5912881.
    Citations: 7     Fields:    Translation:Animals
  11. Castle KD, Chen M, Wisdom AJ, Kirsch DG. Genetically engineered mouse models for studying radiation biology. Transl Cancer Res. 2017 Jul; 6(Suppl 5):S900-S913. PMID: 30733931; PMCID: PMC6363345.
    Citations: 11     
  12. Shammas RL, Fales AM, Crawford BM, Wisdom AJ, Devi GR, Brown DA, Vo-Dinh T, Hollenbeck ST. Human Adipose-Derived Stem Cells Labeled with Plasmonic Gold Nanostars for Cellular Tracking and Photothermal Cancer Cell Ablation. Plast Reconstr Surg. 2017 Apr; 139(4):900e-910e. PMID: 28350664; PMCID: PMC5373491.
    Citations: 5     Fields:    Translation:HumansCells
  13. Spence RD, Wisdom AJ, Cao Y, Hill HM, Mongerson CR, Stapornkul B, Itoh N, Sofroniew MV, Voskuhl RR. Estrogen mediates neuroprotection and anti-inflammatory effects during EAE through ERa signaling on astrocytes but not through ERß signaling on astrocytes or neurons. J Neurosci. 2013 Jun 26; 33(26):10924-33. PMID: 23804112.
    Citations: 74     Fields:    Translation:AnimalsCells
  14. Wisdom AJ, Cao Y, Itoh N, Spence RD, Voskuhl RR. Estrogen receptor-ß ligand treatment after disease onset is neuroprotective in the multiple sclerosis model. J Neurosci Res. 2013 Jul; 91(7):901-8. PMID: 23633287.
    Citations: 13     Fields:    Translation:AnimalsCells
  15. Spence RD, Hamby ME, Umeda E, Itoh N, Du S, Wisdom AJ, Cao Y, Bondar G, Lam J, Ao Y, Sandoval F, Suriany S, Sofroniew MV, Voskuhl RR. Neuroprotection mediated through estrogen receptor-alpha in astrocytes. Proc Natl Acad Sci U S A. 2011 May 24; 108(21):8867-72. PMID: 21555578.
    Citations: 97     Fields:    Translation:AnimalsCells
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.