Harvard Catalyst Profiles

Contact, publication, and social network information about Harvard faculty and fellows.

Hushan Yuan, Ph.D.

Title
Institution
Department
Address
Phone

Bibliographic
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
Newest   |   Oldest   |   Most Cited   |   Most Discussed   |   Timeline   |   Field Summary   |   Plain Text
PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Gholami YH, Yuan H, Wilks MQ, Maschmeyer R, Normandin MD, Josephson L, El Fakhri G, Kuncic Z. A Radio-Nano-Platform for T1/T2 Dual-Mode PET-MR Imaging. Int J Nanomedicine. 2020; 15:1253-1266. PMID: 32161456.
    Citations:    
  2. Gholami YH, Josephson L, Akam EA, Caravan P, Wilks MQ, Pan XZ, Maschmeyer R, Kolnick A, El Fakhri G, Normandin MD, Kuncic Z, Yuan H. A Chelate-Free Nano-Platform for Incorporation of Diagnostic and Therapeutic Isotopes. Int J Nanomedicine. 2020; 15:31-47. PMID: 32021163.
    Citations:    
  3. Yuan H, Wilks MQ, Normandin MD, El Fakhri G, Kaittanis C, Josephson L. Heat-induced radiolabeling and fluorescence labeling of Feraheme nanoparticles for PET/SPECT imaging and flow cytometry. Nat Protoc. 2018 02; 13(2):392-412. PMID: 29370158.
    Citations: 1     Fields:    
  4. Sîrbulescu RF, Boehm CK, Soon E, Wilks MQ, Ilies I, Yuan H, Maxner B, Chronos N, Kaittanis C, Normandin MD, El Fakhri G, Orgill DP, Sluder AE, Poznansky MC. Mature B cells accelerate wound healing after acute and chronic diabetic skin lesions. Wound Repair Regen. 2017 09; 25(5):774-791. PMID: 28922523.
    Citations: 2     Fields:    Translation:AnimalsCells
  5. Klein OJ, Yuan H, Nowell NH, Kaittanis C, Josephson L, Evans CL. An Integrin-Targeted, Highly Diffusive Construct for Photodynamic Therapy. Sci Rep. 2017 10 17; 7(1):13375. PMID: 29042620.
    Citations:    Fields:    
  6. Yuan H, Wilks MQ, El Fakhri G, Normandin MD, Kaittanis C, Josephson L. Heat-induced-radiolabeling and click chemistry: A powerful combination for generating multifunctional nanomaterials. PLoS One. 2017; 12(2):e0172722. PMID: 28225818.
    Citations: 4     Fields:    
  7. Chen HH, Yuan H, Cho H, Feng Y, Ngoy S, Kumar AT, Liao R, Chao W, Josephson L, Sosnovik DE. Theranostic Nucleic Acid Binding Nanoprobe Exerts Anti-inflammatory and Cytoprotective Effects in Ischemic Injury. Theranostics. 2017; 7(4):814-825. PMID: 28382156.
    Citations:    Fields:    Translation:Animals
  8. Normandin MD, Yuan H, Wilks MQ, Chen HH, Kinsella JM, Cho H, Guehl NJ, Absi-Halabi N, Hosseini SM, El Fakhri G, Sosnovik DE, Josephson L. Heat-Induced Radiolabeling of Nanoparticles for Monocyte Tracking by PET. Angew Chem Int Ed Engl. 2015 Oct 26; 54(44):13002-6. PMID: 26368132.
    Citations: 4     Fields:    Translation:AnimalsCells
  9. Wilks MQ, Normandin MD, Yuan H, Cho H, Guo Y, Herisson F, Ayata C, Wooten DW, El Fakhri G, Josephson L. Imaging PEG-like nanoprobes in tumor, transient ischemia, and inflammatory disease models. Bioconjug Chem. 2015 Jun 17; 26(6):1061-9. PMID: 25971846.
    Citations: 1     Fields:    Translation:AnimalsCells
  10. Chen HH, Yuan H, Cho H, Sosnovik DE, Josephson L. Cytoprotective nanoparticles by conjugation of a polyhis tagged annexin V to a nanoparticle drug. Nanoscale. 2015 Feb 14; 7(6):2255-9. PMID: 25572921.
    Citations:    Fields:    Translation:HumansAnimalsCells
  11. Guo Y, Yuan H, Claudio NM, Kura S, Shakerdge N, Mempel TR, Bacskai BJ, Josephson L. PEG-like nanoprobes: multimodal, pharmacokinetically and optically tunable nanomaterials. PLoS One. 2014; 9(4):e95406. PMID: 24781778.
    Citations: 2     Fields:    Translation:AnimalsCells
  12. Yuan H, Cho H, Chen HH, Panagia M, Sosnovik DE, Josephson L. Fluorescent and radiolabeled triphenylphosphonium probes for imaging mitochondria. Chem Commun (Camb). 2013 Nov 14; 49(88):10361-3. PMID: 24072060.
    Citations: 7     Fields:    
  13. Guo Y, Yuan H, Cho H, Kuruppu D, Jokivarsi K, Agarwal A, Shah K, Josephson L. High efficiency diffusion molecular retention tumor targeting. PLoS One. 2013; 8(3):e58290. PMID: 23505478.
    Citations: 5     Fields:    Translation:HumansAnimalsCells
  14. Cho H, Alcantara D, Yuan H, Sheth RA, Chen HH, Huang P, Andersson SB, Sosnovik DE, Mahmood U, Josephson L. Fluorochrome-functionalized nanoparticles for imaging DNA in biological systems. ACS Nano. 2013 Mar 26; 7(3):2032-41. PMID: 23373524.
    Citations: 4     Fields:    Translation:HumansAnimalsCells
  15. Buckle T, Kuil J, van den Berg NS, Bunschoten A, Lamb HJ, Yuan H, Josephson L, Jonkers J, Borowsky AD, van Leeuwen FW. Use of a single hybrid imaging agent for integration of target validation with in vivo and ex vivo imaging of mouse tumor lesions resembling human DCIS. PLoS One. 2013; 8(1):e48324. PMID: 23326303.
    Citations: 6     Fields:    Translation:HumansAnimalsCells
  16. Guo Y, Yuan H, Rice WL, Kumar AT, Goergen CJ, Jokivarsi K, Josephson L. The PEG-fluorochrome shielding approach for targeted probe design. J Am Chem Soc. 2012 Nov 28; 134(47):19338-41. PMID: 23137147.
    Citations: 7     Fields:    Translation:HumansAnimalsCells
  17. Alcantara D, Guo Y, Yuan H, Goergen CJ, Chen HH, Cho H, Sosnovik DE, Josephson L. Fluorochrome-functionalized magnetic nanoparticles for high-sensitivity monitoring of the polymerase chain reaction by magnetic resonance. Angew Chem Int Ed Engl. 2012 Jul 09; 51(28):6904-7. PMID: 22684680.
    Citations: 3     Fields:    
  18. Bunschoten A, Buckle T, Visser NL, Kuil J, Yuan H, Josephson L, Vahrmeijer AL, van Leeuwen FW. Multimodal interventional molecular imaging of tumor margins and distant metastases by targeting avß3 integrin. Chembiochem. 2012 May 07; 13(7):1039-45. PMID: 22505018.
    Citations: 9     Fields:    Translation:Animals
  19. Chen HH, Yuan H, Josephson L, Sosnovik DE. Theranostic Imaging of the Kinases and Proteases that Modulate Cell Death and Survival. Theranostics. 2012; 2(2):148-55. PMID: 22400062.
    Citations: 3     Fields:    
  20. Kuil J, Buckle T, Oldenburg J, Yuan H, Borowsky AD, Josephson L, van Leeuwen FW. Hybrid peptide dendrimers for imaging of chemokine receptor 4 (CXCR4) expression. Mol Pharm. 2011 Dec 05; 8(6):2444-53. PMID: 22085282.
    Citations: 14     Fields:    Translation:HumansCells
  21. Huang S, Chen HH, Yuan H, Dai G, Schuhle DT, Mekkaoui C, Ngoy S, Liao R, Caravan P, Josephson L, Sosnovik DE. Molecular MRI of acute necrosis with a novel DNA-binding gadolinium chelate: kinetics of cell death and clearance in infarcted myocardium. Circ Cardiovasc Imaging. 2011 Nov; 4(6):729-37. PMID: 21836081.
    Citations: 17     Fields:    Translation:AnimalsCells
  22. Kuil J, Buckle T, Yuan H, van den Berg NS, Oishi S, Fujii N, Josephson L, van Leeuwen FW. Synthesis and evaluation of a bimodal CXCR4 antagonistic peptide. Bioconjug Chem. 2011 May 18; 22(5):859-64. PMID: 21480671.
    Citations: 19     Fields:    Translation:HumansAnimalsCells
  23. Shao F, Yuan H, Josephson L, Weissleder R, Hilderbrand SA. Facile Synthesis of Monofunctional Pentamethine Carbocyanine Fluorophores. Dyes Pigm. 2011 Apr 01; 90(2):119-122. PMID: 21475610.
    Citations: 12     
  24. Smith RA, Yuan H, Weissleder R, Cantley LC, Josephson L. A wortmannin-cetuximab as a double drug. Bioconjug Chem. 2009 Nov; 20(11):2185-9. PMID: 19883074.
    Citations:    Fields:    Translation:HumansCells
  25. Stangenberg L, Ellson C, Cortez-Retamozo V, Ortiz-Lopez A, Yuan H, Blois J, Smith RA, Yaffe MB, Weissleder R, Benoist C, Mathis D, Josephson L, Mahmood U. Abrogation of antibody-induced arthritis in mice by a self-activating viridin prodrug and association with impaired neutrophil and endothelial cell function. Arthritis Rheum. 2009 Aug; 60(8):2314-24. PMID: 19644878.
    Citations: 7     Fields:    Translation:AnimalsCells
  26. Smith A, Blois J, Yuan H, Aikawa E, Ellson C, Figueiredo JL, Weissleder R, Kohler R, Yaffe MB, Cantley LC, Josephson L. The antiproliferative cytostatic effects of a self-activating viridin prodrug. Mol Cancer Ther. 2009 Jun; 8(6):1666-75. PMID: 19509266.
    Citations: 8     Fields:    Translation:HumansAnimalsCells
  27. Yuan H, Pupo MT, Blois J, Smith A, Weissleder R, Clardy J, Josephson L. A stabilized demethoxyviridin derivative inhibits PI3 kinase. Bioorg Med Chem Lett. 2009 Aug 01; 19(15):4223-7. PMID: 19523825.
    Citations: 3     Fields:    Translation:Animals
  28. Cortez-Retamozo V, Swirski FK, Waterman P, Yuan H, Figueiredo JL, Newton AP, Upadhyay R, Vinegoni C, Kohler R, Blois J, Smith A, Nahrendorf M, Josephson L, Weissleder R, Pittet MJ. Real-time assessment of inflammation and treatment response in a mouse model of allergic airway inflammation. J Clin Invest. 2008 Dec; 118(12):4058-66. PMID: 19033674.
    Citations: 34     Fields:    Translation:AnimalsCells
  29. Blois J, Yuan H, Smith A, Pacold ME, Weissleder R, Cantley LC, Josephson L. Slow self-activation enhances the potency of viridin prodrugs. J Med Chem. 2008 Aug 14; 51(15):4699-707. PMID: 18630894.
    Citations: 7     Fields:    Translation:HumansCells
  30. Barnes KR, Blois J, Smith A, Yuan H, Reynolds F, Weissleder R, Cantley LC, Josephson L. Fate of a bioactive fluorescent wortmannin derivative in cells. Bioconjug Chem. 2008 Jan; 19(1):130-7. PMID: 17988080.
    Citations: 9     Fields:    Translation:HumansCells
  31. Yuan H, Barnes KR, Weissleder R, Cantley L, Josephson L. Covalent reactions of wortmannin under physiological conditions. Chem Biol. 2007 Mar; 14(3):321-8. PMID: 17379147.
    Citations: 14     Fields:    Translation:Cells
  32. Montet X, Yuan H, Weissleder R, Josephson L. Enzyme-based visualization of receptor-ligand binding in tissues. Lab Invest. 2006 May; 86(5):517-25. PMID: 16568109.
    Citations: 7     Fields:    Translation:HumansAnimalsCells
  33. Yuan H, Luo J, Weissleder R, Cantley L, Josephson L. Wortmannin-C20 conjugates generate wortmannin. J Med Chem. 2006 Jan 26; 49(2):740-7. PMID: 16420059.
    Citations: 11     Fields:    
  34. Yuan H, Luo J, Field S, Weissleder R, Cantley L, Josephson L. Synthesis and activity of C11-modified wortmannin probes for PI3 kinase. Bioconjug Chem. 2005 May-Jun; 16(3):669-75. PMID: 15898736.
    Citations: 5     Fields:    Translation:Cells
Local representatives can answer questions about the Profiles website or help with editing a profile or issues with profile data. For assistance with this profile: HMS/HSDM faculty should contact feedbackcatalyst.harvard.edu. For faculty or fellow appointment updates and changes, please ask your appointing department to contact HMS. For fellow personal and demographic information, contact HMS Human Resources at human_resourceshms.harvard.edu. For faculty personal and demographic information, contact HMS Office for Faculty Affairs at facappthms.harvard.edu.
Yuan's Networks
Click the
Explore
buttons for more information and interactive visualizations!
Concepts (213)
Explore
_
Co-Authors (33)
Explore
_
Similar People (59)
Explore
_
Same Department 
Explore
_
Physical Neighbors
_
Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.