Harvard Catalyst Profiles

Contact, publication, and social network information about Harvard faculty and fellows.

Towia Aron Libermann, Ph.D.

Title
Institution
Department
Address
Phone
Fax
Profile Picture

Mentoring
Available: 01/10/22, Expires: 07/01/23

My lab has a major focus on biomarker discovery and validation using multi-omics technologies, with a particular focus on proteomics data. We are generating large datasets of proteomics data for various precision medicine and diagnostic, predictive, and prognostic applications in human disease. The key challenge with these big data is the development of the most accurate predictor or risk stratification models and to define the pathophysiological pathways associated with these biomarkers. The goal of the project is to apply statistical, machine learning or AI approaches to these big data in order to develop the optimal multi-feature predictor or risk stratification models that eventually can be translated into clinical applications to improve patient management and outcome. Systems biology approaches will also be applied to generate novel insights into the pathophysiological pathways underlying disease development or progression or response to therapy. Larger datasets for various human diseases are available or being generated every week that are available for a student to further analyze. The student will be involved in all aspects of data analysis with the goal to develop the best models with regard to prediction and biological function. Prior skills should include knowledge in at least one of the listed computer languages such as R, Python, Matlab or SAS. Some statistical or machine learning skills would be preferred.

Available: 01/10/22, Expires: 01/01/23

This project is focused on identifying and validating protein biomarkers in blood from patients with various diseases such as postoperative delirium, endometriosis, inflammatory bowel disease, or hepatocellular cancer. We. are using the most comprehensive proteomics platform, the aptamer-based SomaScan, that allows us to measure expression levels of 7,000 proteins in any given sample to identify the discriminating protein biomarkers and fully automated multiplex immunoassays to further validate the biomarkers in larger sample numbers of independent patient cohorts. The goals are to define protein signatures, develop predictor models, generate new insights into the pathophysiological pathways, and identify novel therapeutic targets. The main anticipated outcomes are to predict risk of development of delirium in surgical patients or of endometriosis in premenopausal women, to detect cancers at early stages such as hepatocellular cancer prior to current diagnosis, and to predict and monitor therapeutic response in patients with inflammatory bowel disease. The students will be involved in all aspects of the project and participate in measuring protein expression as well as analysis of proteomic data for biomarker discovery and predictor model development. Students should have primary skills in lab work such as pipetting. Knowledge in statistical analysis or machine learning would be ideal, but not a necessary skill.


Research
The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
  1. R21CA218960 (LIBERMANN, TOWIA A.) Jul 17, 2018 - Jun 30, 2021
    NIH
    Identification of Plasma- and Exosome-Based Protein Biomarkers for Early Detection of Pancreatic Cancer Using SOMAscan Technology
    Role: Principal Investigator
  2. R01AG051658 (MARCANTONIO, EDWARD R) Jan 15, 2016 - Dec 31, 2020
    NIH
    Advancing the Understanding of Postoperative Delirium Mechanisms via Multi-Omics
    Role: Principal Investigator
  3. R21CA187843 (LIBERMANN, TOWIA A.) Jun 12, 2015 - May 31, 2017
    NIH
    Role of Axl in docetaxel resistance in prostate cancer
    Role: Principal Investigator
  4. R21CA176912 (LIBERMANN, TOWIA A.) Apr 15, 2013 - Jul 31, 2015
    NIH
    Novel treatment strategies for enhancing sunitinib response in renal cell cancer
    Role: Principal Investigator
  5. R21CA107352 (LIBERMANN, TOWIA A) May 1, 2005 - Apr 30, 2008
    NIH
    NOVEL APPROACHES TO GENE PROFILING IN OVARIAN CANCER
    Role: Principal Investigator

Bibliographic
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
Newest   |   Oldest   |   Most Cited   |   Most Discussed   |   Timeline   |   Field Summary   |   Plain Text
PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Ross JM, Santarnecchi E, Lian SJ, Fong TG, Touroutoglou A, Cavallari M, Travison TG, Marcantonio ER, Libermann TA, Schmitt EM, Inouye SK, Shafi MM, Pascual-Leone A. Neurophysiologic predictors of individual risk for post-operative delirium after elective surgery. J Am Geriatr Soc. 2022 Oct 13. PMID: 36226896.
    Citations:    Fields:    
  2. Hshieh TT, Schmitt EM, Fong TG, Arnold S, Cavallari M, Dickerson BC, Dillon ST, Jones RN, Libermann TA, Marcantonio ER, Pascual-Leone A, Shafi MM, Touroutoglou A, Travison TG, Gou RY, Tommet D, Abdeen A, Earp B, Kunze L, Lange J, Vlassakov K, Inouye SK. Successful aging after elective surgery II: Study design and methods. J Am Geriatr Soc. 2022 Oct 10. PMID: 36214228.
    Citations:    Fields:    
  3. Sasamoto N, Ngo L, Vitonis AF, Dillon ST, Missmer SA, Libermann TA, Terry KL. Circulating proteomic profiles associated with endometriosis in adolescents and young adults. Hum Reprod. 2022 08 25; 37(9):2042-2053. PMID: 35770801.
    Citations:    Fields:    
  4. Katsumi Y, Wong B, Cavallari M, Fong TG, Alsop DC, Andreano JM, Carvalho N, Brickhouse M, Jones R, Libermann TA, Marcantonio ER, Schmitt E, Shafi MM, Pascual-Leone A, Travison T, Barrett LF, Inouye SK, Dickerson BC, Touroutoglou A. Structural integrity of the anterior mid-cingulate cortex contributes to resilience to delirium in SuperAging. Brain Commun. 2022; 4(4):fcac163. PMID: 35822100; PMCID: PMC9272062.
    Citations: 1     
  5. Pollard JA, Furutani E, Liu S, Esrick E, Cohen LE, Bledsoe J, Liu CW, Lu K, de Haro MJR, Surrallés J, Malsch M, Kuniholm A, Galvin A, Armant M, Kim AS, Ballotti K, Moreau L, Zhou Y, Babushok D, Boulad F, Carroll C, Hartung H, Hont A, Nakano T, Olson T, Sze SG, Thompson AA, Wlodarski MW, Gu X, Libermann TA, D'Andrea A, Grompe M, Weller E, Shimamura A. Metformin for treatment of cytopenias in children and young adults with Fanconi anemia. Blood Adv. 2022 06 28; 6(12):3803-3811. PMID: 35500223; PMCID: PMC9631552.
    Citations:    Fields:    Translation:HumansCTClinical Trials
  6. Haslam DE, Li J, Dillon ST, Gu X, Cao Y, Zeleznik OA, Sasamoto N, Zhang X, Eliassen AH, Liang L, Stampfer MJ, Mora S, Chen ZZ, Terry KL, Gerszten RE, Hu FB, Chan AT, Libermann TA, Bhupathiraju SN. Stability and reproducibility of proteomic profiles in epidemiological studies: comparing the Olink and SOMAscan platforms. Proteomics. 2022 07; 22(13-14):e2100170. PMID: 35598103.
    Citations:    Fields:    Translation:Humans
  7. Rashid A, Zeng C, Motta-Ribeiro G, Dillon ST, Libermann TA, Lessa MA, Bagchi A, Hutchinson J, Vidal Melo MF. Proteomics of lung tissue reveals differences in inflammation and alveolar-capillary barrier response between atelectasis and aerated regions. Sci Rep. 2022 04 29; 12(1):7065. PMID: 35487970; PMCID: PMC9053128.
    Citations:    Fields:    Translation:Humans
  8. Muruve DA, Debiec H, Dillon ST, Gu X, Plaisier E, Can H, Otu HH, Libermann TA, Ronco P. Serum Protein Signatures Using Aptamer-Based Proteomics for Minimal Change Disease and Membranous Nephropathy. Kidney Int Rep. 2022 Jul; 7(7):1539-1556. PMID: 35812291; PMCID: PMC9263421.
    Citations:    
  9. Dillon ST, Otu HH, Ngo LH, Fong TG, Vasunilashorn SM, Xie Z, Kunze LJ, Vlassakov KV, Abdeen A, Lange JK, Earp BE, Cooper ZR, Schmitt EM, Arnold SE, Hshieh TT, Jones RN, Inouye SK, Marcantonio ER, Libermann TA. Patterns and Persistence of Perioperative Plasma and Cerebrospinal Fluid Neuroinflammatory Protein Biomarkers After Elective Orthopedic Surgery Using SOMAscan. Anesth Analg. 2022 Apr 07. PMID: 35389379; PMCID: PMC9537343.
    Citations:    Fields:    
  10. Cavallari M, Fong TG, Touroutoglou A, Dickerson BC, Schmitt E, Travison TG, Marcantonio ER, Ngo LH, Libermann T, Pascual-Leone A, Shafi MM, Inouye SK, Jones RN. Assessment of potential selection bias in neuroimaging studies of postoperative delirium and cognitive decline: lessons from the SAGES study. Brain Imaging Behav. 2022 Aug; 16(4):1732-1740. PMID: 35278158; PMCID: PMC9283208.
    Citations:    Fields:    Translation:Humans
  11. Vasunilashorn SM, Dillon ST, Chan NY, Fong TG, Joseph M, Tripp B, Xie Z, Ngo LH, Lee CG, Elias JA, Otu HH, Inouye SK, Marcantonio ER, Libermann TA. Proteome-Wide Analysis Using SOMAscan Identifies and Validates Chitinase-3-Like Protein 1 as a Risk and Disease Marker of Delirium Among Older Adults Undergoing Major Elective Surgery. J Gerontol A Biol Sci Med Sci. 2022 03 03; 77(3):484-493. PMID: 35239952; PMCID: PMC8893174.
    Citations: 2     Fields:    Translation:Humans
  12. Vasunilashorn SM, Dillon ST, Chan NY, Fong TG, Joseph M, Tripp B, Xie Z, Ngo LH, Lee CG, Elias JA, Otu HH, Inouye SK, Marcantonio ER, Libermann TA. Proteome-Wide Analysis Using SOMAscan Identifies and Validates Chitinase-3-Like Protein 1 as a Risk and Disease Marker of Delirium Among Older Adults Undergoing Major Elective Surgery. J Gerontol A Biol Sci Med Sci. 2022 Mar 03; 77(3):482-491. PMID: 33539520.
    Citations:    Fields:    
  13. Karumanchi SA, Libermann T. Discovery of antiangiogenic factors in the pathogenesis of preeclampsia. Am J Obstet Gynecol. 2022 02; 226(2S):S1035-S1036.e5. PMID: 35177215.
    Citations:    Fields:    Translation:HumansCells
  14. Pérez-Sáez MJ, Uffing A, Leon J, Murakami N, Watanabe A, Borges TJ, Sabbisetti VS, Cureton P, Kenyon V, Keating L, Yee K, Fernandes Satiro CA, Serena G, Hildebrandt F, Riella CV, Libermann TA, Wang M, Pascual J, Bonventre JV, Cravedi P, Fasano A, Riella LV. Corrigendum: Immunological Impact of a Gluten-Free Dairy-Free Diet in Children With Kidney Disease: A Feasibility Study. Front Immunol. 2021; 12:798560. PMID: 34795679; PMCID: PMC8594461.
    Citations:    Fields:    
  15. Oh B, Boyle F, Pavlakis N, Clarke S, Eade T, Hruby G, Lamoury G, Carroll S, Morgia M, Kneebone A, Stevens M, Liu W, Corless B, Molloy M, Kong B, Libermann T, Rosenthal D, Back M. The Gut Microbiome and Cancer Immunotherapy: Can We Use the Gut Microbiome as a Predictive Biomarker for Clinical Response in Cancer Immunotherapy? Cancers (Basel). 2021 Sep 27; 13(19). PMID: 34638308.
    Citations: 3     
  16. Oh B, Boyle F, Pavlakis N, Clarke S, Guminski A, Eade T, Lamoury G, Carroll S, Morgia M, Kneebone A, Hruby G, Stevens M, Liu W, Corless B, Molloy M, Libermann T, Rosenthal D, Back M. Emerging Evidence of the Gut Microbiome in Chemotherapy: A Clinical Review. Front Oncol. 2021; 11:706331. PMID: 34604043.
    Citations:    
  17. Cacciatore S, Wium M, Licari C, Ajayi-Smith A, Masieri L, Anderson C, Salukazana AS, Kaestner L, Carini M, Carbone GM, Catapano CV, Loda M, Libermann TA, Zerbini LF. Inflammatory metabolic profile of South African patients with prostate cancer. Cancer Metab. 2021 Aug 03; 9(1):29. PMID: 34344464.
    Citations: 6     
  18. Md Dom ZI, Satake E, Skupien J, Krolewski B, O'Neil K, Willency JA, Dillon ST, Wilson JM, Kobayashi H, Ihara K, Libermann TA, Pragnell M, Duffin KL, Krolewski AS. Circulating proteins protect against renal decline and progression to end-stage renal disease in patients with diabetes. Sci Transl Med. 2021 06 30; 13(600). PMID: 34193611; PMCID: PMC9022453.
    Citations: 3     Fields:    Translation:Humans
  19. Pérez-Sáez MJ, Uffing A, Leon J, Murakami N, Watanabe A, Borges TJ, Sabbisetti VS, Cureton P, Kenyon V, Keating L, Yee K, Fernandes Satiro CA, Serena G, Hildebrandt F, Riella CV, Libermann TA, Wang M, Pascual J, Bonventre JV, Cravedil P, Fasano A, Riella LV. Immunological Impact of a Gluten-Free Dairy-Free Diet in Children With Kidney Disease: A Feasibility Study. Front Immunol. 2021; 12:624821. PMID: 34149688.
    Citations: 1     Fields:    Translation:HumansCellsCTClinical Trials
  20. Vasunilashorn SM, Ngo LH, Dillon ST, Fong TG, Carlyle BC, Kivisäkk P, Trombetta BA, Vlassakov KV, Kunze LJ, Arnold SE, Xie Z, Inouye SK, Libermann TA, Marcantonio ER. Plasma and cerebrospinal fluid inflammation and the blood-brain barrier in older surgical patients: the Role of Inflammation after Surgery for Elders (RISE) study. J Neuroinflammation. 2021 Apr 30; 18(1):103. PMID: 33931093; PMCID: PMC8088047.
    Citations: 2     Fields:    Translation:Humans
  21. Fong TG, Chan NY, Dillon ST, Zhou W, Tripp B, Ngo LH, Otu HH, Inouye SK, Vasunilashorn SM, Cooper Z, Xie Z, Marcantonio ER, Libermann TA. Identification of Plasma Proteome Signatures Associated With Surgery Using SOMAscan. Ann Surg. 2021 04 01; 273(4):732-742. PMID: 30946084; PMCID: PMC6832727.
    Citations: 12     Fields:    Translation:Humans
  22. Fong TG, Vasunilashorn SM, Gou Y, Libermann TA, Dillon S, Schmitt E, Arnold SE, Kivisäkk P, Carlyle B, Oh ES, Vlassakov K, Kunze L, Hshieh T, Jones RN, Marcantonio ER, Inouye SK. Association of CSF Alzheimer's disease biomarkers with postoperative delirium in older adults. Alzheimers Dement (N Y). 2021; 7(1):e12125. PMID: 33748398; PMCID: PMC7968120.
    Citations: 4     
  23. Larson A, Libermann TA, Bowditch H, Das G, Diakos N, Huggins GS, Rastegar H, Chen FY, Rowin EJ, Maron MS, Chin MT. Plasma Proteomic Profiling in Hypertrophic Cardiomyopathy Patients before and after Surgical Myectomy Reveals Post-Procedural Reduction in Systemic Inflammation. Int J Mol Sci. 2021 Mar 01; 22(5). PMID: 33804404.
    Citations: 4     Fields:    Translation:Humans
  24. Tripp BA, Dillon ST, Yuan M, Asara JM, Vasunilashorn SM, Fong TG, Metzger ED, Inouye SK, Xie Z, Ngo LH, Marcantonio ER, Libermann TA, Otu HH. Targeted metabolomics analysis of postoperative delirium. Sci Rep. 2021 01 15; 11(1):1521. PMID: 33452279.
    Citations: 1     Fields:    Translation:Humans
  25. Ngo LH, Austin Argentieri M, Dillon ST, Kent BV, Kanaya AM, Shields AE, Libermann TA. Plasma protein expression profiles, cardiovascular disease, and religious struggles among South Asians in the MASALA study. Sci Rep. 2021 01 13; 11(1):961. PMID: 33441605.
    Citations: 2     Fields:    Translation:Humans
  26. Yakah W, Singh P, Brown J, Stoll B, Burrin D, Premkumar MH, Otu HH, Gu X, Dillon ST, Libermann TA, Freedman SD, Martin CR. Parenteral lipid emulsions induce unique ileal fatty acid and metabolomic profiles but do not increase the risk of necrotizing enterocolitis in preterm pigs. Am J Physiol Gastrointest Liver Physiol. 2021 02 01; 320(2):G227-G239. PMID: 33236951; PMCID: PMC7948117.
    Citations: 2     Fields:    Translation:HumansAnimals
  27. Fong TG, Vasunilashorn SM, Ngo L, Libermann TA, Dillon ST, Schmitt EM, Pascual-Leone A, Arnold SE, Jones RN, Marcantonio ER, Inouye SK. Association of Plasma Neurofilament Light with Postoperative Delirium. Ann Neurol. 2020 11; 88(5):984-994. PMID: 32881052.
    Citations: 14     Fields:    Translation:Humans
  28. Katsumi Y, Racine AM, Torrado-Carvajal A, Loggia ML, Hooker JM, Greve DN, Hightower BG, Catana C, Cavallari M, Arnold SE, Fong TG, Vasunilashorn SM, Marcantonio ER, Schmitt EM, Xu G, Libermann TA, Barrett LF, Inouye SK, Dickerson BC, Touroutoglou A, Collins JA. The Role of Inflammation after Surgery for Elders (RISE) study: Examination of [11C]PBR28 binding and exploration of its link to post-operative delirium. Neuroimage Clin. 2020; 27:102346. PMID: 32712451.
    Citations: 5     Fields:    Translation:Humans
  29. Morad G, Daisy CC, Otu HH, Libermann TA, Dillon ST, Moses MA. Cdc42-Dependent Transfer of mir301 from Breast Cancer-Derived Extracellular Vesicles Regulates the Matrix Modulating Ability of Astrocytes at the Blood-Brain Barrier. Int J Mol Sci. 2020 May 28; 21(11). PMID: 32481745.
    Citations: 6     Fields:    Translation:HumansAnimalsCells
  30. Furutani E, Shah AS, Zhao Y, Andorsky D, Dedeoglu F, Geddis A, Zhou Y, Libermann TA, Myers KC, Shimamura A. Inflammatory manifestations in patients with Shwachman-Diamond syndrome: A novel phenotype. Am J Med Genet A. 2020 07; 182(7):1754-1760. PMID: 32293785.
    Citations: 1     Fields:    Translation:Humans
  31. Shainker SA, Silver RM, Modest AM, Hacker MR, Hecht JL, Salahuddin S, Dillon ST, Ciampa EJ, D'Alton ME, Otu HH, Abuhamad AZ, Einerson BD, Branch DW, Wylie BJ, Libermann TA, Karumanchi SA. Placenta accreta spectrum: biomarker discovery using plasma proteomics. Am J Obstet Gynecol. 2020 09; 223(3):433.e1-433.e14. PMID: 32199927.
    Citations: 8     Fields:    Translation:Humans
  32. Workman AD, Miyake MM, Nocera AL, Mueller SK, Finn K, Otu HH, Libermann TA, Bleier BS. Unexpected effects of systemic steroids on the CRSwNP proteome: is protein upregulation more important than inhibition? Int Forum Allergy Rhinol. 2020 03; 10(3):334-342. PMID: 32022468.
    Citations: 2     Fields:    Translation:HumansCells
  33. Mueller SK, Nocera AL, Workman A, Libermann T, Dillon ST, Stegmann A, Wurm J, Iro H, Wendler O, Bleier BS. Significant polyomic and functional upregulation of the PAPP-A/IGFBP-4/5/IGF-1 axis in chronic rhinosinusitis with nasal polyps. Int Forum Allergy Rhinol. 2020 04; 10(4):546-555. PMID: 31930684.
    Citations: 2     Fields:    Translation:HumansCells
  34. Vasunilashorn SM, Ngo LH, Inouye SK, Fong TG, Jones RN, Dillon ST, Libermann TA, O'Connor M, Arnold SE, Xie Z, Marcantonio ER. Apolipoprotein E genotype and the association between C-reactive protein and postoperative delirium: Importance of gene-protein interactions. Alzheimers Dement. 2020 03; 16(3):572-580. PMID: 31761478.
    Citations: 5     Fields:    Translation:Humans
  35. Shubin AV, Kollar B, Dillon ST, Pomahac B, Libermann TA, Riella LV. Blood proteome profiling using aptamer-based technology for rejection biomarker discovery in transplantation. Sci Data. 2019 12 09; 6(1):314. PMID: 31819064.
    Citations: 3     Fields:    Translation:Humans
  36. Hshieh TT, Vasunilashorn SM, D'Aquila ML, Arnold SE, Dickerson BC, Fong TG, Jones RN, Marcantonio ER, Schmitt EM, Xu G, Gou Y, Chen F, Kunze LJ, Vlassakov KV, Abdeen AR, Lange JK, Earp BE, Touroutoglou A, Carlyle BC, Kivisakk-Webb P, Travison TG, Dillon ST, Libermann TA, Inouye SK. The Role of Inflammation after Surgery for Elders (RISE) study: Study design, procedures, and cohort profile. Alzheimers Dement (Amst). 2019 Dec; 11:752-762. PMID: 31737775; PMCID: PMC6849121.
    Citations: 7     
  37. Daiello LA, Racine AM, Yun Gou R, Marcantonio ER, Xie Z, Kunze LJ, Vlassakov KV, Inouye SK, Jones RN, Alsop D, Travison T, Arnold S, Cooper Z, Dickerson B, Fong T, Metzger E, Pascual-Leone A, Schmitt EM, Shafi M, Cavallari M, Dai W, Dillon ST, McElhaney J, Guttmann C, Hshieh T, Kuchel G, Libermann T, Ngo L, Press D, Saczynski J, Vasunilashorn S, O'Connor M, Kimchi E, Strauss J, Wong B, Belkin M, Ayres D, Callery M, Pomposelli F, Wright J, Schermerhorn M, Abrantes T, Albuquerque A, Bertrand S, Brown A, Callahan A, D'Aquila M, Dowal S, Fox M, Gallagher J, Anna Gersten R, Hodara A, Helfand B, Inloes J, Kettell J, Kuczmarska A, Nee J, Nemeth E, Ochsner L, Palihnich K, Parisi K, Puelle M, Rastegar S, Vella M, Xu G, Bryan M, Guess J, Enghorn D, Gross A, Gou Y, Habtemariam D, Isaza I, Kosar C, Rockett C, Tommet D, Gruen T, Ross M, Tasker K, Gee J, Kolanowski A, Pisani M, de Rooij S, Rogers S, Studenski S, Stern Y, Whittemore A, Gottlieb G, Orav J, Sperling R. Postoperative Delirium and Postoperative Cognitive Dysfunction: Overlap and Divergence. Anesthesiology. 2019 09; 131(3):477-491. PMID: 31166241; PMCID: PMC6692220.
    Citations: 55     Fields:    Translation:Humans
  38. Xie Z, Kuhns DB, Gu X, Otu HH, Libermann TA, Gallin JI, Parikh SM, Druey KM. Neutrophil activation in systemic capillary leak syndrome (Clarkson disease). J Cell Mol Med. 2019 08; 23(8):5119-5127. PMID: 31210423.
    Citations: 4     Fields:    Translation:HumansCells
  39. Joyce CE, Saadatpour A, Ruiz-Gutierrez M, Bolukbasi OV, Jiang L, Thomas DD, Young S, Hofmann I, Sieff CA, Myers KC, Whangbo J, Libermann TA, Nusbaum C, Yuan GC, Shimamura A, Novina CD. TGFß signaling underlies hematopoietic dysfunction and bone marrow failure in Shwachman-Diamond Syndrome. J Clin Invest. 2019 06 18; 129(9):3821-3826. PMID: 31211692; PMCID: PMC6715362.
    Citations: 12     Fields:    Translation:HumansCells
  40. Fong TG, Vasunilashorn SM, Libermann T, Marcantonio ER, Inouye SK. Delirium and Alzheimer disease: A proposed model for shared pathophysiology. Int J Geriatr Psychiatry. 2019 06; 34(6):781-789. PMID: 30773695; PMCID: PMC6830540.
    Citations: 19     Fields:    
  41. Mueller SK, Nocera AL, Dillon ST, Libermann TA, Wendler O, Bleier BS. Tissue and Exosomal Serine Protease Inhibitors Are Significantly Overexpressed in Chronic Rhinosinusitis With Nasal Polyps. Am J Rhinol Allergy. 2019 Jul; 33(4):359-368. PMID: 30810048.
    Citations: 6     Fields:    Translation:HumansCells
  42. Paccez JD, Duncan K, Sekar D, Correa RG, Wang Y, Gu X, Bashin M, Chibale K, Libermann TA, Zerbini LF. Dihydroartemisinin inhibits prostate cancer via JARID2/miR-7/miR-34a-dependent downregulation of Axl. Oncogenesis. 2019 Feb 19; 8(3):14. PMID: 30783079; PMCID: PMC6381097.
    Citations: 32     
  43. Workman AD, Nocera AL, Mueller SK, Otu HH, Libermann TA, Bleier BS. Translating transcription: proteomics in chronic rhinosinusitis with nasal polyps reveals significant discordance with messenger RNA expression. Int Forum Allergy Rhinol. 2019 07; 9(7):776-786. PMID: 30775848.
    Citations: 3     Fields:    Translation:HumansCells
  44. Vasunilashorn SM, Ngo LH, Chan NY, Zhou W, Dillon ST, Otu HH, Inouye SK, Wyrobnik I, Kuchel GA, McElhaney JE, Xie Z, Alsop DC, Jones RN, Libermann TA, Marcantonio ER. Development of a Dynamic Multi-Protein Signature of Postoperative Delirium. J Gerontol A Biol Sci Med Sci. 2019 01 16; 74(2):261-268. PMID: 29529166; PMCID: PMC6333936.
    Citations: 13     Fields:    Translation:Humans
  45. Wu D, Nocera AL, Mueller SK, Finn K, Libermann TA, Bleier BS. Osteitis is associated with dysregulated pro-osteoblastic activity in patients with nasal polyps. Laryngoscope. 2019 03; 129(3):E102-E109. PMID: 30537181.
    Citations: 3     Fields:    Translation:HumansCells
  46. Mueller SK, Nocera AL, Dillon ST, Gu X, Wendler O, Otu HH, Libermann TA, Bleier BS. Noninvasive exosomal proteomic biosignatures, including cystatin SN, peroxiredoxin-5, and glycoprotein VI, accurately predict chronic rhinosinusitis with nasal polyps. Int Forum Allergy Rhinol. 2019 02; 9(2):177-186. PMID: 30485711.
    Citations: 10     Fields:    Translation:HumansCells
  47. Nocera AL, Mueller SK, Stephan JR, Hing L, Seifert P, Han X, Lin DT, Amiji MM, Libermann T, Bleier BS. Exosome swarms eliminate airway pathogens and provide passive epithelial immunoprotection through nitric oxide. J Allergy Clin Immunol. 2019 04; 143(4):1525-1535.e1. PMID: 30442371.
    Citations: 18     Fields:    Translation:HumansCells
  48. Kollar B, Shubin A, Borges TJ, Tasigiorgos S, Win TS, Lian CG, Dillon ST, Gu X, Wyrobnik I, Murphy GF, Pomahac B, Libermann TA, Riella LV. Increased levels of circulating MMP3 correlate with severe rejection in face transplantation. Sci Rep. 2018 10 08; 8(1):14915. PMID: 30297859; PMCID: PMC6175842.
    Citations: 8     Fields:    Translation:HumansCells
  49. Sircar M, Rosales IA, Selig MK, Xu D, Zsengeller ZK, Stillman IE, Libermann TA, Karumanchi SA, Thadhani RI. Complement 7 Is Up-Regulated in Human Early Diabetic Kidney Disease. Am J Pathol. 2018 10; 188(10):2147-2154. PMID: 30253844; PMCID: PMC6180251.
    Citations: 17     Fields:    Translation:HumansCells
  50. Vasunilashorn SM, Ngo LH, Jones RN, Inouye SK, Hall KT, Gallagher J, Dillon ST, Xie Z, Libermann TA, Marcantonio ER. The Association Between C-Reactive Protein and Postoperative Delirium Differs by Catechol-O-Methyltransferase Genotype. Am J Geriatr Psychiatry. 2019 01; 27(1):1-8. PMID: 30424994.
    Citations: 7     Fields:    Translation:Humans
  51. Mueller SK, Nocera AL, Dillon ST, Wu D, Libermann TA, Bleier BS. Highly multiplexed proteomic analysis reveals significant tissue and exosomal coagulation pathway derangement in chronic rhinosinusitis with nasal polyps. Int Forum Allergy Rhinol. 2018 12; 8(12):1438-1444. PMID: 30091854.
    Citations: 10     Fields:    Translation:HumansCells
  52. Wu D, Mueller SK, Nocera AL, Finn K, Libermann TA, Bleier BS. TREM-1 Neutrophil Activation Pathway Is Suppressed in Eosinophilic Nasal Polyps. Am J Rhinol Allergy. 2018 Sep; 32(5):359-368. PMID: 29961347.
    Citations: 3     Fields:    Translation:HumansCells
  53. Kim CH, Tworoger SS, Stampfer MJ, Dillon ST, Gu X, Sawyer SJ, Chan AT, Libermann TA, Eliassen AH. Stability and reproducibility of proteomic profiles measured with an aptamer-based platform. Sci Rep. 2018 05 30; 8(1):8382. PMID: 29849057.