Harvard Catalyst Profiles

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Keisuke Sako, M.D.

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Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Mori Y, Fink C, Ichimura T, Sako K, Mori M, Lee NN, Aschauer P, Padmanabha Das KM, Hong S, Song M, Padera RF, Weins A, Lee LP, Nasr ML, Dekaban GA, Dikeakos JD, Bonventre JV. KIM-1/TIM-1 is a Receptor for SARS-CoV-2 in Lung and Kidney. medRxiv. 2022 Jan 11. PMID: 32995803.
    Citations: 1     
  2. Pradhan SJ, Reddy PC, Smutny M, Sharma A, Sako K, Oak MS, Shah R, Pal M, Deshpande O, Dsilva G, Tang Y, Mishra R, Deshpande G, Giraldez AJ, Sonawane M, Heisenberg CP, Galande S. Satb2 acts as a gatekeeper for major developmental transitions during early vertebrate embryogenesis. Nat Commun. 2021 10 19; 12(1):6094. PMID: 34667153.
    Citations:    Fields:    Translation:AnimalsCells
  3. Tsujita K, Satow R, Asada S, Nakamura Y, Arnes L, Sako K, Fujita Y, Fukami K, Itoh T. Homeostatic membrane tension constrains cancer cell dissemination by counteracting BAR protein assembly. Nat Commun. 2021 10 11; 12(1):5930. PMID: 34635648.
    Citations:    Fields:    Translation:HumansCells
  4. Watanabe-Takano H, Ochi H, Chiba A, Matsuo A, Kanai Y, Fukuhara S, Ito N, Sako K, Miyazaki T, Tainaka K, Harada I, Sato S, Sawada Y, Minamino N, Takeda S, Ueda HR, Yasoda A, Mochizuki N. Mechanical load regulates bone growth via periosteal Osteocrin. Cell Rep. 2021 07 13; 36(2):109380. PMID: 34260913.
    Citations: 5     Fields:    Translation:AnimalsCells
  5. Makiishi S, Furuichi K, Yamamura Y, Sako K, Shinozaki Y, Toyama T, Kitajima S, Iwata Y, Sakai N, Shimizu M, Hirose-Sugiura T, Kaneko S, Kato Y, Wada T. Carnitine/organic cation transporter 1 precipitates the progression of interstitial fibrosis through oxidative stress in diabetic nephropathy in mice. Sci Rep. 2021 04 27; 11(1):9093. PMID: 33907247.
    Citations: 1     Fields:    Translation:Animals
  6. Yamamura Y, Furuichi K, Murakawa Y, Hirabayashi S, Yoshihara M, Sako K, Kitajima S, Toyama T, Iwata Y, Sakai N, Hosomichi K, Murphy PM, Tajima A, Okita K, Osafune K, Kaneko S, Wada T. Identification of candidate PAX2-regulated genes implicated in human kidney development. Sci Rep. 2021 04 27; 11(1):9123. PMID: 33907292.
    Citations:    Fields:    Translation:HumansAnimalsCells
  7. Sako K, Furuichi K, Yamamura Y, Oshima M, Toyama T, Kaneko S, Wada T. Association between the recurrence period of acute kidney injury and mortality: a single-centre retrospective observational study in Japan. BMJ Open. 2019 06 16; 9(6):e023259. PMID: 31209081.
    Citations: 2     Fields:    Translation:Humans
  8. Barone V, Lang M, Krens SFG, Pradhan SJ, Shamipour S, Sako K, Sikora M, Guet CC, Heisenberg CP. An Effective Feedback Loop between Cell-Cell Contact Duration and Morphogen Signaling Determines Cell Fate. Dev Cell. 2017 10 23; 43(2):198-211.e12. PMID: 29033362.
    Citations: 14     Fields:    Translation:AnimalsCells
  9. Sako K, Pradhan SJ, Barone V, Inglés-Prieto Á, Müller P, Ruprecht V, Capek D, Galande S, Janovjak H, Heisenberg CP. Optogenetic Control of Nodal Signaling Reveals a Temporal Pattern of Nodal Signaling Regulating Cell Fate Specification during Gastrulation. Cell Rep. 2016 07 19; 16(3):866-77. PMID: 27396324.
    Citations: 31     Fields:    Translation:AnimalsCells
  10. Ruprecht V, Wieser S, Callan-Jones A, Smutny M, Morita H, Sako K, Barone V, Ritsch-Marte M, Sixt M, Voituriez R, Heisenberg CP. Cortical contractility triggers a stochastic switch to fast amoeboid cell motility. Cell. 2015 Feb 12; 160(4):673-685. PMID: 25679761.
    Citations: 127     Fields:    Translation:AnimalsCells
  11. Zhang J, Fukuhara S, Sako K, Takenouchi T, Kitani H, Kume T, Koh GY, Mochizuki N. Angiopoietin-1/Tie2 signal augments basal Notch signal controlling vascular quiescence by inducing delta-like 4 expression through AKT-mediated activation of beta-catenin. J Biol Chem. 2011 Mar 11; 286(10):8055-8066. PMID: 21212269.
    Citations: 48     Fields:    Translation:Cells
  12. Fukuhara S, Sako K, Noda K, Zhang J, Minami M, Mochizuki N. Angiopoietin-1/Tie2 receptor signaling in vascular quiescence and angiogenesis. Histol Histopathol. 2010 03; 25(3):387-96. PMID: 20054809.
    Citations: 66     Fields:    Translation:HumansAnimalsCells
  13. Fukuhara S, Sako K, Noda K, Nagao K, Miura K, Mochizuki N. Tie2 is tied at the cell-cell contacts and to extracellular matrix by angiopoietin-1. Exp Mol Med. 2009 Mar 31; 41(3):133-9. PMID: 19293632.
    Citations: 31     Fields:    Translation:HumansAnimalsCells
  14. Sako K, Fukuhara S, Minami T, Hamakubo T, Song H, Kodama T, Fukamizu A, Gutkind JS, Koh GY, Mochizuki N. Angiopoietin-1 induces Kruppel-like factor 2 expression through a phosphoinositide 3-kinase/AKT-dependent activation of myocyte enhancer factor 2. J Biol Chem. 2009 Feb 27; 284(9):5592-601. PMID: 19106103.
    Citations: 25     Fields:    Translation:HumansCells
  15. Fukuhara S, Sako K, Minami T, Noda K, Kim HZ, Kodama T, Shibuya M, Takakura N, Koh GY, Mochizuki N. Differential function of Tie2 at cell-cell contacts and cell-substratum contacts regulated by angiopoietin-1. Nat Cell Biol. 2008 May; 10(5):513-26. PMID: 18425120.
    Citations: 157     Fields:    Translation:HumansAnimalsCells
  16. Fukuhra S, Sakurai A, Yamagishi A, Sako K, Mochizuki N. Vascular endothelial cadherin-mediated cell-cell adhesion regulated by a small GTPase, Rap1. J Biochem Mol Biol. 2006 Mar 31; 39(2):132-9. PMID: 16584626.
    Citations: 16     Fields:    Translation:HumansAnimals
  17. Sakurai A, Fukuhara S, Yamagishi A, Sako K, Kamioka Y, Masuda M, Nakaoka Y, Mochizuki N. MAGI-1 is required for Rap1 activation upon cell-cell contact and for enhancement of vascular endothelial cadherin-mediated cell adhesion. Mol Biol Cell. 2006 Feb; 17(2):966-76. PMID: 16339077.
    Citations: 65     Fields:    Translation:HumansAnimalsCells
  18. Sako K, Okuma Y, Hosoi T, Nomura Y. STAT3 activation and c-FOS expression in the brain following peripheral administration of bacterial DNA. J Neuroimmunol. 2005 Jan; 158(1-2):40-9. PMID: 15589036.
    Citations: 3     Fields:    Translation:AnimalsCells
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.