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profileAltan Ercan, Ph.D.

TitleAssistant Professor of Medicine
InstitutionBrigham and Women's Hospital
DepartmentMedicine
AddressBrigham and Women's Hospital
Smith Bldg/Medicine- Rm 538D
1 Jimmy Fund Way
Boston MA 02115
Phone617/525-1084
Fax617/525-1010
vCardDownload vCard (login for email)

Collapse Biography 
Collapse awards and honors
1995 - 2002Scholarship for MS and PhD studies
2002 - 2002Publication award
2005 - 2005Travel award
2011 - 2013Kelly award
2012 - 2014K12
2012 - 2012Best Papers in Musculoskeletal Research

Collapse Bibliographic 
Collapse selected publications
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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  1. Ercan A, Kohrt WM, Cui J, Deane KD, Pezer M, Yu EW, Hausmann JS, Campbell H, Kaiser UB, Rudd PM, Lauc G, Wilson JF, Finkelstein JS, Nigrovic PA. Estrogens regulate glycosylation of IgG in women and men. JCI Insight. 2017 Feb 23; 2(4):e89703. PMID: 28239652.
    View in: PubMed
  2. Nguyen TK, Reinink P, El Messlaki C, Im JS, Ercan A, Porcelli SA, Van Rhijn I. Correction: Expression Patterns of Bovine CD1 In Vivo and Assessment of the Specificities of the Anti-Bovine CD1 Antibodies. PLoS One. 2015; 10(6):e0129755. PMID: 26046785; PMCID: PMC4457881.
  3. Nguyen TK, Reinink P, El Messlaki C, Im JS, Ercan A, Porcelli SA, Van Rhijn I. Expression patterns of bovine CD1 in vivo and assessment of the specificities of the anti-bovine CD1 antibodies. PLoS One. 2015; 10(3):e0121923. PMID: 25815476; PMCID: PMC4376853.
  4. Dauber A, Ercan A, Lee J, James P, Jacobs PP, Ashline DJ, Wang SR, Miller T, Hirschhorn JN, Nigrovic PA, Sackstein R. Congenital disorder of fucosylation type 2c (LADII) presenting with short stature and developmental delay with minimal adhesion defect. Hum Mol Genet. 2014 Jun 01; 23(11):2880-7. PMID: 24403049; PMCID: PMC4014190.
  5. Ackerman ME, Crispin M, Yu X, Baruah K, Boesch AW, Harvey DJ, Dugast AS, Heizen EL, Ercan A, Choi I, Streeck H, Nigrovic PA, Bailey-Kellogg C, Scanlan C, Alter G. Natural variation in Fc glycosylation of HIV-specific antibodies impacts antiviral activity. J Clin Invest. 2013 May; 123(5):2183-92. PMID: 23563315; PMCID: PMC3637034.
  6. Adamczyk B, Struwe WB, Ercan A, Nigrovic PA, Rudd PM. Characterization of fibrinogen glycosylation and its importance for serum/plasma N-glycome analysis. J Proteome Res. 2013 Jan 04; 12(1):444-54. PMID: 23151259.
    View in: PubMed
  7. Ercan A, Barnes MG, Hazen M, Tory H, Henderson L, Dedeoglu F, Fuhlbrigge RC, Grom A, Holm IA, Kellogg M, Kim S, Adamczyk B, Rudd PM, Son MB, Sundel RP, Foell D, Glass DN, Thompson SD, Nigrovic PA. Multiple juvenile idiopathic arthritis subtypes demonstrate proinflammatory IgG glycosylation. Arthritis Rheum. 2012 Sep; 64(9):3025-33. PMID: 22549726; PMCID: PMC3429730.
  8. Ercan A, Cui J, Hazen MM, Batliwalla F, Royle L, Rudd PM, Coblyn JS, Shadick N, Weinblatt ME, Gregersen P, Lee DM, Nigrovic PA. Hypogalactosylation of serum N-glycans fails to predict clinical response to methotrexate and TNF inhibition in rheumatoid arthritis. Arthritis Res Ther. 2012 Mar 05; 14(2):R43. PMID: 22390545; PMCID: PMC3446410.
  9. Ercan A, Cui J, Chatterton DE, Deane KD, Hazen MM, Brintnell W, O'Donnell CI, Derber LA, Weinblatt ME, Shadick NA, Bell DA, Cairns E, Solomon DH, Holers VM, Rudd PM, Lee DM. Aberrant IgG galactosylation precedes disease onset, correlates with disease activity, and is prevalent in autoantibodies in rheumatoid arthritis. Arthritis Rheum. 2010 Aug; 62(8):2239-48. PMID: 20506563; PMCID: PMC4118465.
  10. Ercan A, Tay WM, Grossman SH, Ming LJ. Mechanistic role of each metal ion in Streptomyces dinuclear aminopeptidase: PEPTIDE hydrolysis and 7x10(10)-fold rate enhancement of phosphodiester hydrolysis. J Inorg Biochem. 2010 Jan; 104(1):19-29. PMID: 19879003.
    View in: PubMed
  11. Ercan A, Park HI, Ming LJ. A "moonlighting" dizinc aminopeptidase from Streptomyces griseus: mechanisms for peptide hydrolysis and the 4 x 10(10)-fold acceleration of the alternative phosphodiester hydrolysis. Biochemistry. 2006 Nov 21; 45(46):13779-93. PMID: 17105197.
    View in: PubMed
  12. Ercan A, Panico M, Sutton-Smith M, Dell A, Morris HR, Matta KL, Gay DF, West CM. Molecular characterization of a novel UDP-galactose:fucoside alpha3-galactosyltransferase that modifies Skp1 in the cytoplasm of Dictyostelium. J Biol Chem. 2006 May 05; 281(18):12713-21. PMID: 16495217.
    View in: PubMed
  13. van der Wel H, Ercan A, West CM. The Skp1 prolyl hydroxylase from Dictyostelium is related to the hypoxia-inducible factor-alpha class of animal prolyl 4-hydroxylases. J Biol Chem. 2005 Apr 15; 280(15):14645-55. PMID: 15705570.
    View in: PubMed
  14. Ercan A, West CM. Kinetic analysis of a Golgi UDP-GlcNAc:polypeptide-Thr/Ser N-acetyl-alpha-glucosaminyltransferase from Dictyostelium. Glycobiology. 2005 May; 15(5):489-500. PMID: 15616122.
    View in: PubMed
  15. Ketcham C, Wang F, Fisher SZ, Ercan A, van der Wel H, Locke RD, Sirajud-Doulah K, Matta KL, West CM. Specificity of a soluble UDP-galactose: fucoside alpha1,3-galactosyltransferase that modifies the cytoplasmic glycoprotein Skp1 in Dictyostelium. J Biol Chem. 2004 Jul 09; 279(28):29050-9. PMID: 15123660.
    View in: PubMed
  16. Ercan A, Grossman SH. Proteolytic susceptibility of creatine kinase isozymes and arginine kinase. Biochem Biophys Res Commun. 2003 Jul 11; 306(4):1014-8. PMID: 12821144.
    View in: PubMed
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