Harvard Catalyst Profiles

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Roosmarijn Jacolina Jutten, Ph.D.

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  1. Jutten RJ, Papp KV, Hendrix S, Ellison N, Langbaum JB, Donohue MC, Hassenstab J, Maruff P, Rentz DM, Harrison J, Cummings J, Scheltens P, Sikkes SAM. Why a clinical trial is as good as its outcome measure: A framework for the selection and use of cognitive outcome measures for clinical trials of Alzheimer's disease. Alzheimers Dement. 2023 02; 19(2):708-720. PMID: 36086926; PMCID: PMC9931632.
    Citations: 2     Fields:    Translation:Humans
  2. Dubbelman MA, Verrijp M, Terwee CB, Jutten RJ, Postema MC, Barkhof F, Berckel BNM, Gillissen F, Teeuwen V, Teunissen C, van de Flier WM, Scheltens P, Sikkes SAM. Determining the Minimal Important Change of Everyday Functioning in Dementia: Pursuing Clinical Meaningfulness. Neurology. 2022 08 30; 99(9):e954-e964. PMID: 35641309; PMCID: PMC9502738.
    Citations: 1     Fields:    Translation:Humans
  3. Vonk JMJ, Gross AL, Zammit AR, Bertola L, Avila JF, Jutten RJ, Gaynor LS, Suemoto CK, Kobayashi LC, O'Connell ME, Elugbadebo O, Amofa PA, Staffaroni AM, Arce Rentería M, Turney IC, Jones RN, Manly JJ, Lee J, Zahodne LB. Cross-national harmonization of cognitive measures across HRS HCAP (USA) and LASI-DAD (India). PLoS One. 2022; 17(2):e0264166. PMID: 35213581; PMCID: PMC8880818.
    Citations: 1     Fields:    Translation:Humans
  4. Jutten RJ, Rentz DM, Fu JF, Mayblyum DV, Amariglio RE, Buckley RF, Properzi MJ, Maruff P, Stark CE, Yassa MA, Johnson KA, Sperling RA, Papp KV. Monthly At-Home Computerized Cognitive Testing to Detect Diminished Practice Effects in Preclinical Alzheimer's Disease. Front Aging Neurosci. 2021; 13:800126. PMID: 35095476; PMCID: PMC8792465.
    Citations: 6     
  5. Verrijp M, Dubbelman MA, Visser LNC, Jutten RJ, Nijhuis EW, Zwan MD, van Hout HPJ, Scheltens P, van der Flier WM, Sikkes SAM. Everyday Functioning in a Community-Based Volunteer Population: Differences Between Participant- and Study Partner-Report. Front Aging Neurosci. 2021; 13:761932. PMID: 35069172; PMCID: PMC8767803.
    Citations:    
  6. Jutten RJ, Thompson L, Sikkes SAM, Maruff P, Molinuevo JL, Zetterberg H, Alber J, Faust D, Gauthier S, Gold M, Harrison J, Lee AKW, Snyder PJ. A Neuropsychological Perspective on Defining Cognitive Impairment in the Clinical Study of Alzheimer's Disease: Towards a More Continuous Approach. J Alzheimers Dis. 2022; 86(2):511-524. PMID: 35124638.
    Citations: 2     Fields:    Translation:Humans
  7. Ulugut H, Stek S, Wagemans LEE, Jutten RJ, Keulen MA, Bouwman FH, Prins ND, Lemstra AW, Krudop W, Teunissen CE, van Berckel BNM, Ossenkoppele R, Barkhof F, van der Flier WM, Scheltens P, Pijnenburg YAL. The natural history of primary progressive aphasia: beyond aphasia. J Neurol. 2022 Mar; 269(3):1375-1385. PMID: 34216263; PMCID: PMC8857134.
    Citations: 7     Fields:    Translation:Humans
  8. Jutten RJ, Sikkes SAM, Van der Flier WM, Scheltens P, Visser PJ, Tijms BM. Finding Treatment Effects in Alzheimer Trials in the Face of Disease Progression Heterogeneity. Neurology. 2021 06 01; 96(22):e2673-e2684. PMID: 34550903; PMCID: PMC8205463.
    Citations: 13     Fields:    Translation:Humans
  9. Zwan MD, van der Flier WM, Cleutjens S, Schouten TC, Vermunt L, Jutten RJ, van Maurik IS, Sikkes SAM, Flenniken D, Howell T, Weiner MW, Scheltens P, Prins ND. Dutch Brain Research Registry for study participant recruitment: Design and first results. Alzheimers Dement (N Y). 2021; 7(1):e12132. PMID: 33614897; PMCID: PMC7882519.
    Citations: 8     
  10. Choi SE, Mukherjee S, Gibbons LE, Sanders RE, Jones RN, Tommet D, Mez J, Trittschuh EH, Saykin A, Lamar M, Rabin L, Foldi NS, Sikkes S, Jutten RJ, Grandoit E, Mac Donald C, Risacher S, Groot C, Ossenkoppele R, Crane PK. Development and validation of language and visuospatial composite scores in ADNI. Alzheimers Dement (N Y). 2020; 6(1):e12072. PMID: 33313380; PMCID: PMC7718716.
    Citations: 14     
  11. Sikkes SAM, Tang Y, Jutten RJ, Wesselman LMP, Turkstra LS, Brodaty H, Clare L, Cassidy-Eagle E, Cox KL, Chételat G, Dautricourt S, Dhana K, Dodge H, Dröes RM, Hampstead BM, Holland T, Lampit A, Laver K, Lutz A, Lautenschlager NT, McCurry SM, Meiland FJM, Morris MC, Mueller KD, Peters R, Ridel G, Spector A, van der Steen JT, Tamplin J, Thompson Z, Bahar-Fuchs A. Toward a theory-based specification of non-pharmacological treatments in aging and dementia: Focused reviews and methodological recommendations. Alzheimers Dement. 2021 02; 17(2):255-270. PMID: 33215876.
    Citations: 11     Fields:    Translation:Humans
  12. Dubbelman MA, Jutten RJ, Tomaszewski Farias SE, Amariglio RE, Buckley RF, Visser PJ, Rentz DM, Johnson KA, Properzi MJ, Schultz A, Donovan N, Gatchell JR, Teunissen CE, Van Berckel BNM, Van der Flier WM, Sperling RA, Papp KV, Scheltens P, Marshall GA, Sikkes SAM. Decline in cognitively complex everyday activities accelerates along the Alzheimer's disease continuum. Alzheimers Res Ther. 2020 10 29; 12(1):138. PMID: 33121534.
    Citations: 2     Fields:    Translation:Humans
  13. Jutten RJ, Sikkes SAM, Amariglio RE, Buckley RF, Properzi MJ, Marshall GA, Rentz DM, Johnson KA, Teunissen CE, Van Berckel BNM, Van der Flier WM, Scheltens P, Sperling RA, Papp KV. Identifying Sensitive Measures of Cognitive Decline at Different Clinical Stages of Alzheimer's Disease. J Int Neuropsychol Soc. 2021 05; 27(5):426-438. PMID: 33046162; PMCID: PMC8041916.
    Citations: 11     Fields:    Translation:Humans
  14. Bruderer-Hofstetter M, Dubbelman MA, Meichtry A, Koehn F, Münzer T, Jutten RJ, Scheltens P, Sikkes SAM, Niedermann K. Cross-cultural adaptation and validation of the Amsterdam Instrumental Activities of Daily Living questionnaire short version German for Switzerland. Health Qual Life Outcomes. 2020 Oct 02; 18(1):323. PMID: 33008394.
    Citations: 2     Fields:    Translation:Humans
  15. Ulugut Erkoyun H, Groot C, Heilbron R, Nelissen A, van Rossum J, Jutten R, Koene T, van der Flier WM, Wattjes MP, Scheltens P, Ossenkoppele R, Barkhof F, Pijnenburg Y. A clinical-radiological framework of the right temporal variant of frontotemporal dementia. Brain. 2020 09 01; 143(9):2831-2843. PMID: 32830218; PMCID: PMC9172625.
    Citations: 25     Fields:    Translation:Humans
  16. Jutten RJ, Grandoit E, Foldi NS, Sikkes SAM, Jones RN, Choi SE, Lamar ML, Louden DKN, Rich J, Tommet D, Crane PK, Rabin LA. Lower practice effects as a marker of cognitive performance and dementia risk: A literature review. Alzheimers Dement (Amst). 2020; 12(1):e12055. PMID: 32671181; PMCID: PMC7346865.
    Citations: 21     
  17. Jutten RJ, Harrison JE, Brunner AJ, Vreeswijk R, van Deelen RAJ, de Jong FJ, Opmeer EM, Ritchie CW, Aleman A, Scheltens P, Sikkes SAM. The Cognitive-Functional Composite is sensitive to clinical progression in early dementia: Longitudinal findings from the Catch-Cog study cohort. Alzheimers Dement (N Y). 2020; 6(1):e12020. PMID: 32313832; PMCID: PMC7164406.
    Citations: 8     
  18. Jutten RJ, Harrison JE, Lee Meeuw Kjoe PR, Ingala S, Vreeswijk R, van Deelen RAJ, de Jong FJ, Opmeer EM, Aleman A, Ritchie CW, Scheltens P, Sikkes SAM. Assessing cognition and daily function in early dementia using the cognitive-functional composite: findings from the Catch-Cog study cohort. Alzheimers Res Ther. 2019 05 15; 11(1):45. PMID: 31092277.
    Citations: 10     Fields:    Translation:Humans
  19. Babulal GM, Quiroz YT, Albensi BC, Arenaza-Urquijo E, Astell AJ, Babiloni C, Bahar-Fuchs A, Bell J, Bowman GL, Brickman AM, Chételat G, Ciro C, Cohen AD, Dilworth-Anderson P, Dodge HH, Dreux S, Edland S, Esbensen A, Evered L, Ewers M, Fargo KN, Fortea J, Gonzalez H, Gustafson DR, Head E, Hendrix JA, Hofer SM, Johnson LA, Jutten R, Kilborn K, Lanctôt KL, Manly JJ, Martins RN, Mielke MM, Morris MC, Murray ME, Oh ES, Parra MA, Rissman RA, Roe CM, Santos OA, Scarmeas N, Schneider LS, Schupf N, Sikkes S, Snyder HM, Sohrabi HR, Stern Y, Strydom A, Tang Y, Terrera GM, Teunissen C, Melo van Lent D, Weinborn M, Wesselman L, Wilcock DM, Zetterberg H, O'Bryant SE. Perspectives on ethnic and racial disparities in Alzheimer's disease and related dementias: Update and areas of immediate need. Alzheimers Dement. 2019 02; 15(2):292-312. PMID: 30555031; PMCID: PMC6368893.
    Citations: 156     Fields:    Translation:Humans
  20. Jutten RJ, Dicks E, Vermaat L, Barkhof F, Scheltens P, Tijms BM, Sikkes SAM. Impairment in complex activities of daily living is related to neurodegeneration in Alzheimer's disease-specific regions. Neurobiol Aging. 2019 03; 75:109-116. PMID: 30557769.
    Citations: 9     Fields:    Translation:HumansCells
  21. Yilmaz T, Jutten RJ, Santos CY, Hernandez KA, Snyder PJ. Discontinuation and nonpublication of interventional clinical trials conducted in patients with mild cognitive impairment and Alzheimer's disease. Alzheimers Dement (N Y). 2018; 4:161-164. PMID: 29955660; PMCID: PMC6021544.
    Citations: 5     
  22. Facal D, Carabias MAR, Pereiro AX, Lojo-Seoane C, Campos-Magdaleno M, Jutten RJ, Sikkes SAM, Juncos-Rabadán O. Assessing Everyday Activities Across the Dementia Spectrum with the Amsterdam IADL Questionnaire. Curr Alzheimer Res. 2018; 15(13):1261-1266. PMID: 30251604.
    Citations: 5     Fields:    Translation:Humans
  23. Jutten RJ, Harrison J, Lee Meeuw Kjoe PR, Opmeer EM, Schoonenboom NSM, de Jong FJ, Ritchie CW, Scheltens P, Sikkes SAM. A novel cognitive-functional composite measure to detect changes in early Alzheimer's disease: Test-retest reliability and feasibility. Alzheimers Dement (Amst). 2018; 10:153-160. PMID: 29780863; PMCID: PMC5956799.
    Citations: 11     
  24. Jutten RJ, Peeters CFW, Leijdesdorff SMJ, Visser PJ, Maier AB, Terwee CB, Scheltens P, Sikkes SAM. Detecting functional decline from normal aging to dementia: Development and validation of a short version of the Amsterdam IADL Questionnaire. Alzheimers Dement (Amst). 2017; 8:26-35. PMID: 28462387; PMCID: PMC5403784.
    Citations: 33     
  25. Jutten RJ, Harrison J, de Jong FJ, Aleman A, Ritchie CW, Scheltens P, Sikkes SAM. A composite measure of cognitive and functional progression in Alzheimer's disease: Design of the Capturing Changes in Cognition study. Alzheimers Dement (N Y). 2017 Jan; 3(1):130-138. PMID: 29067324; PMCID: PMC5651369.
    Citations: 17     
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.