Harvard Catalyst Profiles

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Patricia Louise Brazee, Ph.D.


The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
  1. F31HL132454 (BRAZEE, PATRICIA LOUISE) Sep 1, 2016 - Aug 31, 2019
    LUBAC Mediated Epithelial Signaling During Influenza A Infection
    Role: Principal Investigator

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Dada LA, Welch LC, Magnani ND, Ren Z, Han H, Brazee PL, Celli D, Flozak AS, Weng A, Herrerias MM, Kryvenko V, Vadász I, Runyan CE, Abdala-Valencia H, Shigemura M, Casalino-Matsuda SM, Misharin AV, Budinger GRS, Gottardi CJ, Sznajder JI. Hypercapnia alters stroma-derived Wnt production to limit ß-catenin signaling and proliferation in AT2 cells. JCI Insight. 2023 Feb 22; 8(4). PMID: 36626234; PMCID: PMC9977495.
    Citations:    Fields:    Translation:HumansCells
  2. Knipe RS, Nurunnabi M, Probst CK, Spinney JJ, Abe E, Bose RJC, Ha K, Logue A, Nguyen T, Servis R, Drummond M, Haring A, Brazee PL, Medoff BD, McCarthy JR. Myofibroblast-specific inhibition of the Rho kinase-MRTF-SRF pathway using nanotechnology for the prevention of pulmonary fibrosis. Am J Physiol Lung Cell Mol Physiol. 2023 02 01; 324(2):L190-L198. PMID: 36625494; PMCID: PMC9925159.
    Citations:    Fields:    Translation:HumansAnimalsCells
  3. Knipe RS, Spinney JJ, Abe EA, Probst CK, Franklin A, Logue A, Giacona F, Drummond M, Griffith J, Brazee PL, Hariri LP, Montesi SB, Black KE, Hla T, Kuo A, Cartier A, Engelbrecht E, Christoffersen C, Shea BS, Tager AM, Medoff BD. Endothelial-Specific Loss of Sphingosine-1-Phosphate Receptor 1 Increases Vascular Permeability and Exacerbates Bleomycin-induced Pulmonary Fibrosis. Am J Respir Cell Mol Biol. 2022 01; 66(1):38-52. PMID: 34343038; PMCID: PMC8803357.
    Citations: 1     Fields:    Translation:AnimalsCells
  4. Brazee PL, Sznajder JI. Targeting the Linear Ubiquitin Assembly Complex to Modulate the Host Response and Improve Influenza A Virus Induced Lung Injury. Arch Bronconeumol (Engl Ed). 2020 09; 56(9):586-591. PMID: 33994643; PMCID: PMC7489339.
    Citations:    Fields:    Translation:HumansAnimalsCells
  5. Brazee PL, Sznajder JI. Targeting the Linear Ubiquitin Assembly Complex to Modulate the Host Response and Improve Influenza A Virus Induced Lung Injury. Arch Bronconeumol (Engl Ed). 2020 Sep; 56(9):586-591. PMID: 32405132; PMCID: PMC7218391.
    Citations:    Fields:    Translation:HumansAnimalsCells
  6. Brazee PL, Morales-Nebreda L, Magnani ND, Garcia JG, Misharin AV, Ridge KM, Budinger GRS, Iwai K, Dada LA, Sznajder JI. Linear ubiquitin assembly complex regulates lung epithelial-driven responses during influenza infection. J Clin Invest. 2020 03 02; 130(3):1301-1314. PMID: 31714898; PMCID: PMC7269564.
    Citations: 6     Fields:    Translation:HumansAnimalsCells
  7. Brazee PL, Dada LA. Splice Wars: The Role of MLCK Isoforms in Ventilation-induced Lung Injury. Am J Respir Cell Mol Biol. 2018 05; 58(5):549-550. PMID: 29714632; PMCID: PMC5946334.
    Citations:    Fields:    Translation:HumansCells
  8. Knipe RS, Probst CK, Lagares D, Franklin A, Spinney JJ, Brazee PL, Grasberger P, Zhang L, Black KE, Sakai N, Shea BS, Liao JK, Medoff BD, Tager AM. The Rho Kinase Isoforms ROCK1 and ROCK2 Each Contribute to the Development of Experimental Pulmonary Fibrosis. Am J Respir Cell Mol Biol. 2018 04; 58(4):471-481. PMID: 29211497; PMCID: PMC5894496.
    Citations: 29     Fields:    Translation:HumansAnimalsCells
  9. Magnani ND, Dada LA, Queisser MA, Brazee PL, Welch LC, Anekalla KR, Zhou G, Vagin O, Misharin AV, Budinger GRS, Iwai K, Ciechanover AJ, Sznajder JI. HIF and HOIL-1L-mediated PKC? degradation stabilizes plasma membrane Na,K-ATPase to protect against hypoxia-induced lung injury. Proc Natl Acad Sci U S A. 2017 11 21; 114(47):E10178-E10186. PMID: 29109255; PMCID: PMC5703319.
    Citations: 14     Fields:    Translation:HumansAnimalsCells
  10. Brazee PL, Soni PN, Tokhtaeva E, Magnani N, Yemelyanov A, Perlman HR, Ridge KM, Sznajder JI, Vagin O, Dada LA. FXYD5 Is an Essential Mediator of the Inflammatory Response during Lung Injury. Front Immunol. 2017; 8:623. PMID: 28620381.
    Citations: 14     Fields:    
  11. Shea BS, Probst CK, Brazee PL, Rotile NJ, Blasi F, Weinreb PH, Black KE, Sosnovik DE, Van Cott EM, Violette SM, Caravan P, Tager AM. Uncoupling of the profibrotic and hemostatic effects of thrombin in lung fibrosis. JCI Insight. 2017 May 04; 2(9). PMID: 28469072.
    Citations: 26     Fields:    
  12. Brazee P, Dada LA, Sznajder JI. Role of Linear Ubiquitination in Health and Disease. Am J Respir Cell Mol Biol. 2016 06; 54(6):761-8. PMID: 26848516; PMCID: PMC4942223.
    Citations: 11     Fields:    Translation:HumansAnimalsCells
  13. King GD, Chen C, Huang MM, Zeldich E, Brazee PL, Schuman ER, Robin M, Cuny GD, Glicksman MA, Abraham CR. Identification of novel small molecules that elevate Klotho expression. Biochem J. 2012 Jan 01; 441(1):453-61. PMID: 21939436; PMCID: PMC3677209.
    Citations: 31     Fields:    Translation:AnimalsCells
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.