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Omer Hidir Yilmaz, Ph.D., M.D.

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Research
The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
  1. R01CA257523 (CHAN, ANDREW T) Apr 5, 2021 - Mar 31, 2026
    NIH
    Effects of inflammaging on intestinal epithelial cells and aspirin chemoprevention.
    Role: Co-Principal Investigator
  2. R01CA245314 (YILMAZ, OMER) Sep 1, 2020 - May 31, 2025
    NIH
    Impact of fasting on intestinal stem cells and cancer
    Role: Principal Investigator
  3. U01CA250554 (LU, TIMOTHY) Jul 8, 2020 - Jun 30, 2023
    NIH
    Developing high-throughput genetic perturbation strategies for single cells in cancer organoids
    Role: Co-Principal Investigator
  4. R01DK126545 (KWON, DOUGLAS) Jul 1, 2020 - Jun 30, 2025
    NIH
    Mechanisms of HIV-associated epithelial intestinal stem cell (ISC) dysfunction
    Role: Co-Principal Investigator
  5. R01CA211184 (YILMAZ, OMER) Dec 23, 2016 - Nov 30, 2021
    NIH
    Dietary control of stem cells in physiology and cancer
    Role: Principal Investigator

Bibliographic
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Das Adhikari U, Eng G, Farcasanu M, Avena LE, Choudhary MC, Triant VA, Flagg M, Schiff AE, Gomez I, Froehle LM, Diefenbach TJ, Ronsard L, Lingwood D, Lee GC, Rabi SA, Erstad D, Velmahos G, Li JZ, Hodin R, Stone JR, Honko AN, Griffiths A, Yilmaz ÖH, Kwon DS. Fecal Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-Cov-2) RNA Is Associated With Decreased Coronavirus Disease 2019 (COVID-19) Survival. Clin Infect Dis. 2022 03 23; 74(6):1081-1084. PMID: 34245255.
    Citations: 2     Fields:    
  2. Freed-Pastor WA, Lambert LJ, Ely ZA, Pattada NB, Bhutkar A, Eng G, Mercer KL, Garcia AP, Lin L, Rideout WM, Hwang WL, Schenkel JM, Jaeger AM, Bronson RT, Westcott PMK, Hether TD, Divakar P, Reeves JW, Deshpande V, Delorey T, Phillips D, Yilmaz OH, Regev A, Jacks T. The CD155/TIGIT axis promotes and maintains immune evasion in neoantigen-expressing pancreatic cancer. Cancer Cell. 2021 10 11; 39(10):1342-1360.e14. PMID: 34358448.
    Citations: 8     Fields:    Translation:HumansAnimalsCells
  3. Neyaz A, Odze RD, Rickelt S, Nieman LT, Bledsoe JR, Mahadevan KK, Arora K, Jeck WR, Taylor MS, Gala M, Patil DT, Yilmaz OH, Rivera MN, Ting DT, Deshpande V. LGR5 in Barrett's Esophagus and its Utility in Predicting Patients at Increased Risk of Advanced Neoplasia. Clin Transl Gastroenterol. 2020 12 22; 12(1):e00272. PMID: 33464729.
    Citations:    Fields:    Translation:Humans
  4. Rickelt S, Condon C, Mana M, Whittaker C, Pfirschke C, Roper J, Patil DT, Brown I, Mattia AR, Zukerberg L, Zhao Q, Chetty R, Lauwers GY, Neyaz A, Leijssen LGJ, Boylan K, Yilmaz OH, Deshpande V, Hynes RO. Agrin in the Muscularis Mucosa Serves as a Biomarker Distinguishing Hyperplastic Polyps from Sessile Serrated Lesions. Clin Cancer Res. 2020 03 15; 26(6):1277-1287. PMID: 31852835.
    Citations: 3     Fields:    Translation:Humans
  5. Brackett DG, Neyaz A, Arora K, Masia R, Mattia A, Zukerberg L, Misdraji J, Goyal L, Zhu AX, Ferrone CR, Yilmaz OH, Deshpande V. Cholangiolar pattern and albumin in situ hybridisation enable a diagnosis of intrahepatic cholangiocarcinoma. J Clin Pathol. 2020 Jan; 73(1):23-29. PMID: 31422372.
    Citations: 2     Fields:    Translation:HumansCells
  6. Biton M, Haber AL, Rogel N, Burgin G, Beyaz S, Schnell A, Ashenberg O, Su CW, Smillie C, Shekhar K, Chen Z, Wu C, Ordovas-Montanes J, Alvarez D, Herbst RH, Zhang M, Tirosh I, Dionne D, Nguyen LT, Xifaras ME, Shalek AK, von Andrian UH, Graham DB, Rozenblatt-Rosen O, Shi HN, Kuchroo V, Yilmaz OH, Regev A, Xavier RJ. T Helper Cell Cytokines Modulate Intestinal Stem Cell Renewal and Differentiation. Cell. 2018 11 15; 175(5):1307-1320.e22. PMID: 30392957.
    Citations: 126     Fields:    Translation:AnimalsCells
  7. Haber AL, Biton M, Rogel N, Herbst RH, Shekhar K, Smillie C, Burgin G, Delorey TM, Howitt MR, Katz Y, Tirosh I, Beyaz S, Dionne D, Zhang M, Raychowdhury R, Garrett WS, Rozenblatt-Rosen O, Shi HN, Yilmaz O, Xavier RJ, Regev A. A single-cell survey of the small intestinal epithelium. Nature. 2017 11 16; 551(7680):333-339. PMID: 29144463.
    Citations: 411     Fields:    Translation:AnimalsCells
  8. Kedrin D, Gandhi SC, Wolf M, Roper J, Yilmaz O, Corey K, Khalili H, Stanford FC, Gala M. Bariatric Surgery Prior to Index Screening Colonoscopy Is Associated With a Decreased Rate of Colorectal Adenomas in Obese Individuals. Clin Transl Gastroenterol. 2017 Feb 09; 8(2):e73. PMID: 28181993.
    Citations: 4     Fields:    
  9. Strijbis K, Yilmaz OH, Dougan SK, Esteban A, Gröne A, Kumamoto CA, Ploegh HL. Intestinal colonization by Candida albicans alters inflammatory responses in Bruton's tyrosine kinase-deficient mice. PLoS One. 2014; 9(11):e112472. PMID: 25379804.
    Citations: 4     Fields:    Translation:HumansAnimalsCells
  10. Lamming DW, Mihaylova MM, Katajisto P, Baar EL, Yilmaz OH, Hutchins A, Gultekin Y, Gaither R, Sabatini DM. Depletion of Rictor, an essential protein component of mTORC2, decreases male lifespan. Aging Cell. 2014 Oct; 13(5):911-7. PMID: 25059582.
    Citations: 58     Fields:    Translation:AnimalsCells
  11. Lassen KG, Kuballa P, Conway KL, Patel KK, Becker CE, Peloquin JM, Villablanca EJ, Norman JM, Liu TC, Heath RJ, Becker ML, Fagbami L, Horn H, Mercer J, Yilmaz OH, Jaffe JD, Shamji AF, Bhan AK, Carr SA, Daly MJ, Virgin HW, Schreiber SL, Stappenbeck TS, Xavier RJ. Atg16L1 T300A variant decreases selective autophagy resulting in altered cytokine signaling and decreased antibacterial defense. Proc Natl Acad Sci U S A. 2014 May 27; 111(21):7741-6. PMID: 24821797.
    Citations: 156     Fields:    Translation:AnimalsCells
  12. Chudnovsky Y, Kim D, Zheng S, Whyte WA, Bansal M, Bray MA, Gopal S, Theisen MA, Bilodeau S, Thiru P, Muffat J, Yilmaz OH, Mitalipova M, Woolard K, Lee J, Nishimura R, Sakata N, Fine HA, Carpenter AE, Silver SJ, Verhaak RG, Califano A, Young RA, Ligon KL, Mellinghoff IK, Root DE, Sabatini DM, Hahn WC, Chheda MG. ZFHX4 interacts with the NuRD core member CHD4 and regulates the glioblastoma tumor-initiating cell state. Cell Rep. 2014 Jan 30; 6(2):313-24. PMID: 24440720.
    Citations: 58     Fields:    Translation:HumansAnimalsCells
  13. Gupta NK, Yilmaz O, Fisher M, Yajnik V. Abatacept: a new treatment option for refractory adult autoimmune enteropathy. J Clin Gastroenterol. 2014 Jan; 48(1):55-8. PMID: 24045285.
    Citations: 5     Fields:    Translation:HumansCells
  14. Conway KL, Kuballa P, Song JH, Patel KK, Castoreno AB, Yilmaz OH, Jijon HB, Zhang M, Aldrich LN, Villablanca EJ, Peloquin JM, Goel G, Lee IA, Mizoguchi E, Shi HN, Bhan AK, Shaw SY, Schreiber SL, Virgin HW, Shamji AF, Stappenbeck TS, Reinecker HC, Xavier RJ. Atg16l1 is required for autophagy in intestinal epithelial cells and protection of mice from Salmonella infection. Gastroenterology. 2013 Dec; 145(6):1347-57. PMID: 23973919.
    Citations: 117     Fields:    Translation:HumansAnimalsCells
  15. Arnason T, Pino MS, Yilmaz O, Kirley SD, Rueda BR, Chung DC, Zukerberg LR. Cables1 is a tumor suppressor gene that regulates intestinal tumor progression in Apc(Min) mice. Cancer Biol Ther. 2013 Jul; 14(7):672-8. PMID: 23792637.
    Citations: 14     Fields:    Translation:HumansAnimalsCells
  16. Curry NL, Mino-Kenudson M, Oliver TG, Yilmaz OH, Yilmaz VO, Moon JY, Jacks T, Sabatini DM, Kalaany NY. Pten-null tumors cohabiting the same lung display differential AKT activation and sensitivity to dietary restriction. Cancer Discov. 2013 Aug; 3(8):908-21. PMID: 23719831.
    Citations: 20     Fields:    Translation:HumansAnimalsCells
  17. Tse JY, Wu S, Shinagare SA, Lauwers GY, Yilmaz O, Wu CL, Deshpande V. Peutz-Jeghers syndrome: a critical look at colonic Peutz-Jeghers polyps. Mod Pathol. 2013 Sep; 26(9):1235-40. PMID: 23599156.
    Citations: 8     Fields:    Translation:Humans
  18. Birsoy K, Wang T, Possemato R, Yilmaz OH, Koch CE, Chen WW, Hutchins AW, Gultekin Y, Peterson TR, Carette JE, Brummelkamp TR, Clish CB, Sabatini DM. MCT1-mediated transport of a toxic molecule is an effective strategy for targeting glycolytic tumors. Nat Genet. 2013 Jan; 45(1):104-8. PMID: 23202129.
    Citations: 99     Fields:    Translation:HumansAnimalsCells
  19. Yilmaz OH, Deshpande V. Pathology and Genetics of Pancreatic Neoplasms. Surg Pathol Clin. 2012 Dec; 5(4):941-59. PMID: 26838509.
    Citations:    Fields:    
  20. Wang H, Chen Y, Fernandez-Del Castillo C, Yilmaz O, Deshpande V. Heterogeneity in signaling pathways of gastroenteropancreatic neuroendocrine tumors: a critical look at notch signaling pathway. Mod Pathol. 2013 Jan; 26(1):139-47. PMID: 22918166.
    Citations: 21     Fields:    Translation:HumansCells
  21. Kelly PJ, Shinagare S, Sainani N, Hong X, Ferrone C, Yilmaz O, Fernández-del Castillo C, Lauwers GY, Deshpande V. Cystic papillary pattern in pancreatic ductal adenocarcinoma: a heretofore undescribed morphologic pattern that mimics intraductal papillary mucinous carcinoma. Am J Surg Pathol. 2012 May; 36(5):696-701. PMID: 22367300.
    Citations: 7     Fields:    Translation:Humans
  22. Lee JY, Nakada D, Yilmaz OH, Tothova Z, Joseph NM, Lim MS, Gilliland DG, Morrison SJ. mTOR activation induces tumor suppressors that inhibit leukemogenesis and deplete hematopoietic stem cells after Pten deletion. Cell Stem Cell. 2010 Nov 05; 7(5):593-605. PMID: 21040901.
    Citations: 106     Fields:    Translation:AnimalsCells
  23. Oravecz-Wilson KI, Philips ST, Yilmaz OH, Ames HM, Li L, Crawford BD, Gauvin AM, Lucas PC, Sitwala K, Downing JR, Morrison SJ, Ross TS. Persistence of leukemia-initiating cells in a conditional knockin model of an imatinib-responsive myeloproliferative disorder. Cancer Cell. 2009 Aug 04; 16(2):137-48. PMID: 19647224.
    Citations: 36     Fields:    Translation:HumansAnimalsCells
  24. Levi BP, Yilmaz OH, Duester G, Morrison SJ. Aldehyde dehydrogenase 1a1 is dispensable for stem cell function in the mouse hematopoietic and nervous systems. Blood. 2009 Feb 19; 113(8):1670-80. PMID: 18971422.
    Citations: 46     Fields:    Translation:AnimalsCells
  25. Eser I, Kapran Z, Altan T, Ozel Karatas M, Aydin D, Okaygun E, Yilmaz OF. Isolates and antibiotic sensitivity of eighty culture-proven endophthalmitis cases from Istanbul. Ophthalmologica. 2008; 222(3):157-60. PMID: 18497523.
    Citations: 4     Fields:    Translation:HumansAnimalsCells
  26. Kiel MJ, Yilmaz OH, Morrison SJ. CD150- cells are transiently reconstituting multipotent progenitors with little or no stem cell activity. Blood. 2008 Apr 15; 111(8):4413-4; author reply 4414-5. PMID: 18398056.
    Citations: 32     Fields:    Translation:AnimalsCells
  27. Yilmaz OH, Morrison SJ. The PI-3kinase pathway in hematopoietic stem cells and leukemia-initiating cells: a mechanistic difference between normal and cancer stem cells. Blood Cells Mol Dis. 2008 Jul-Aug; 41(1):73-6. PMID: 18387833.
    Citations: 15     Fields:    Translation:AnimalsCells
  28. Yilmaz OH, Valdez R, Theisen BK, Guo W, Ferguson DO, Wu H, Morrison SJ. Pten dependence distinguishes haematopoietic stem cells from leukaemia-initiating cells. Nature. 2006 May 25; 441(7092):475-82. PMID: 16598206.
    Citations: 598     Fields:    Translation:AnimalsCells
  29. Kim I, He S, Yilmaz OH, Kiel MJ, Morrison SJ. Enhanced purification of fetal liver hematopoietic stem cells using SLAM family receptors. Blood. 2006 Jul 15; 108(2):737-44. PMID: 16569764.
    Citations: 101     Fields:    Translation:AnimalsCells
  30. Yilmaz OH, Kiel MJ, Morrison SJ. SLAM family markers are conserved among hematopoietic stem cells from old and reconstituted mice and markedly increase their purity. Blood. 2006 Feb 01; 107(3):924-30. PMID: 16219798.
    Citations: 111     Fields:    Translation:AnimalsCells
  31. Kiel MJ, Yilmaz OH, Iwashita T, Yilmaz OH, Terhorst C, Morrison SJ. SLAM family receptors distinguish hematopoietic stem and progenitor cells and reveal endothelial niches for stem cells. Cell. 2005 Jul 01; 121(7):1109-21. PMID: 15989959.
    Citations: 1347     Fields:    Translation:AnimalsCells
  32. Kiel MJ, Iwashita T, Yilmaz OH, Morrison SJ. Spatial differences in hematopoiesis but not in stem cells indicate a lack of regional patterning in definitive hematopoietic stem cells. Dev Biol. 2005 Jul 01; 283(1):29-39. PMID: 15913595.
    Citations: 25     Fields:    Translation:AnimalsCells
  33. Kim I, Yilmaz OH, Morrison SJ. CD144 (VE-cadherin) is transiently expressed by fetal liver hematopoietic stem cells. Blood. 2005 Aug 01; 106(3):903-5. PMID: 15831702.
    Citations: 39     Fields:    Translation:AnimalsCells
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.