Harvard Catalyst Profiles

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Gonzalo Patricio Labarca Trucios, M.D.

Title
Institution
Department
Address
Phone
Profile Picture

Biography
Universidad del Desarrollo, ChileMD12/2012Medical Doctor
Pontificia Universidad Catolica, ChileResidency04/2016Internal Medicine
Harvard Medical School, Boston, USAPostdoctoral10/2022Sleep Medicine
2010
"Principles and values in Medical School" Award, Universidad Del Desarrollo
2015
Award For Best Scientific Research, 48 Chilean Congress Of Respiratory Diseases
2019
Awarded as Fellow of The American College of Physicians (ACP)
2020
Award For Best Scientific Research, 13 Latin American Association of Thorax (ALAT) Congress
2021
Award For Best Original Investigation in Chile During 2020, Medical Society of Santiago
2021
Award For Best Scientific Research, XLII Chilean Congress of Internal Medicine
2021
Honorable Mention,20th Sleep & Health Benefit Dinner, Sleep Medicine Division-Harvard Medical School
2022
Abstract Scholarship Award,Sleep and Respiratory Neurobiology (SRN)/ American Thoracic Society
2022
Small Research Grant, Sleep Research Society Foundation

Overview
Gonzalo Labarca MD, FACP, is an Instructor in Medicine at the Brigham and Women’s Hospital, Harvard Medical School. Dr. Labarca is a physician-scientist with a research focus on investigating pathways that modulate the relationship between Obstructive Sleep Apnea and worse health outcomes, as well as evidence-based medicine in Sleep Medicine.

He received his MD from the University of Desarrollo, Chile, in 2012 and performed Internal Medicine residency training at Pontificia Universidad Catolica de Chile. After five years of clinical practice and as academic coordinator of the Internal Medicine Residency at the University of Concepcion, Chile. He enrolled in a T32 Research training program in Sleep, circadian, and Respiratory Neurobiology at Sleep Medicine Division, Harvard Medical School.

Dr. Labarca serves as associate Editor for ARS Medical, Chilean Journal of Respiratory Diseases, Guest Editor for Frontiers in Medicine/ Respiratory Medicine, and a peer reviewer in several Q1 journals. He is also an active member of the Chilean society of respiratory diseases, the American College of Physicians, the American Thoracic Society, and the American Academy of Sleep Medicine. To facilitate professional development, he advocates for Latino/Hispanic representation in sleep medicine.

He has received numerous awards, including Best Medical student in 2010, the Chilean Society of Respiratory Medicine (SER Chile) award, Awarded as a fellow of the American College of Physicians (ACP), Latin American Association of thorax (ALAT) research scholar award, Medical Society of Santiago (SMS) Research Award, Best publication in Chile during 2020 award, Sleep and Respiratory Neurobiology assembly/American Thoracic Society scholarship award.

Dr. Labarca has over 100 publications, including the author of original investigations, reviews, Systematic Reviews and Meta-analyses, international consensus, editorials, and chapters in high-impact journals such as The Lancet of Respiratory Medicine, American Journal of Respiratory and Critical Care Medicine, Sleep Medicine Reviews, SLEEP, Chest, and European Respiratory Journal. He is involved in media relations to increase awareness of sleep disorders, has appeared on numerous national news broadcasts, and has been an invited lecturer on a national and international level.

Research
The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
  1. 7868 (Gonzalo Labarca) Oct 1, 2022 - Oct 31, 2023
    CHEST foundation
    Phenotyping Obstructive Sleep Apnea in Latin American women: The Latin American Sleep Network (LATAM Sleep Net)
    Role Description: In this project, we plan to quantitatively describe the clinical and novel OSA-driven phenotypes (hypoxic burden, delta heart rate) among women from different sleep clinics in Latin America. We also plan to test whether hypoxic burden or delta heart rate predicts CPAP response after one month of therapy.
    Role: Principal Investigator
  2. 1R21HL161766-01 (Ali Azarbarzin) Feb 1, 2022 - Jan 31, 2024
    NIH/NHLBI
    Novel physiologically-driven phenotypes for the prognosis of cardiovascular outcomes in sleep apnea: Toward precision medicine in sleep health
    Role Description: In this project, we plan to use two novel sleep apnea-specific metrics to predict the risk of incident hypertension, diabetes, and cardiovascular disease across multiple cohorts using an individual patient data (IPD) meta-analysis and examine the extent to which the effect varies by race, sex, and age. We also plan to test the predictive ability of these novel markers when added to an established 10-year CVD prediction model: the Pooled Cohort Equation to estimate 10-year atherosclerotic cardiovascular disease (ASCVD) risk.
    Role: Co-Investigator
  3. 254-FP-21 (Gonzalo Labarca) Nov 1, 2021 - Nov 1, 2022
    American Academy of Sleep Medicine (AASM)
    Association between the sleep apnea specific hypoxic burden (SASHB) with incident neurocognitive impairment
    Role Description: To determine if the SAHSB can identify individuals with OSA with an increased prevalence and incidence of irreversible neurocognitive impairment. We plan to determine the strength of association of SASHB with the prevalence and incidence of neurocognitive impairment in older men in the MrOS (training dataset) and determinate the consistency and reproducibility of the association of SASHB with incident NI in the ARIC study included in the SHHS (validation dataset).
    Role: Principal Investigator

Bibliographic
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Messineo L, Gell L, Calianese N, Sofer T, Vena D, Azarbarzin A, Labarca G, Taranto-Montemurro L, Yang HC, Wang TY, Kim M, Smith H, White D, Sands S, Wellman A. Effect of Pimavanserin on the Respiratory Arousal Threshold from Sleep: A Randomized Trial. Ann Am Thorac Soc. 2022 12; 19(12):2062-2069. PMID: 35947827; PMCID: PMC9743476.
    Citations:    Fields:    Translation:Humans
  2. García-Hidalgo MC, González J, Benítez ID, Carmona P, Santisteve S, Pérez-Pons M, Moncusí-Moix A, Gort-Paniello C, Rodríguez-Jara F, Molinero M, Belmonte T, Torres G, Labarca G, Nova-Lamperti E, Caballero J, Bermejo-Martin JF, Ceccato A, Fernández-Barat L, Ferrer R, Garcia-Gasulla D, Menéndez R, Motos A, Peñuelas O, Riera J, Torres A, Barbé F, de Gonzalo-Calvo D. Identification of circulating microRNA profiles associated with pulmonary function and radiologic features in survivors of SARS-CoV-2-induced ARDS. Emerg Microbes Infect. 2022 Dec; 11(1):1537-1549. PMID: 35603455; PMCID: PMC9176679.
    Citations: 3     Fields:    Translation:HumansCellsCTClinical Trials
  3. Labarca G, Montenegro R, Oscullo G, Henriquez-Beltran M, Uribe JP, Gómez-Olivas JD, Garcia-Ortega A, Martínez-García MÁ. Placebo response in objective and subjective measures of hypersomnia in randomized clinical trials on obstructive sleep apnea. A systematic review and meta-analysis. Sleep Med Rev. 2023 02; 67:101720. PMID: 36495752.
    Citations:    Fields:    Translation:Humans
  4. Targa ADS, Benítez ID, González J, Torres G, Santisteve S, Vaca R, Minguez O, Aguilà M, Carmona P, Moncusí-Moix A, Gort-Paniello C, Labarca G, Caballero J, Barberà C, Torres A, de Gonzalo-Calvo D, Barbé F. Sleep and circadian health 6?months after critical COVID-19 disease. Respirology. 2022 12; 27(12):1083-1088. PMID: 36210340; PMCID: PMC9874423.
    Citations: 1     Fields:    Translation:Humans
  5. Azarbarzin A, Zinchuk A, Wellman A, Labarca G, Vena D, Gell L, Messineo L, White DP, Gottlieb DJ, Redline S, Peker Y, Sands SA. Cardiovascular Benefit of Continuous Positive Airway Pressure in Adults with Coronary Artery Disease and Obstructive Sleep Apnea without Excessive Sleepiness. Am J Respir Crit Care Med. 2022 09 15; 206(6):767-774. PMID: 35579605; PMCID: PMC9799106.
    Citations: 6     Fields:    Translation:Humans
  6. Yu Lee-Mateus A, Reisenauer J, Garcia-Saucedo JC, Abia-Trujillo D, Buckarma EH, Edell ES, Grage RA, Bowman AW, Labarca G, Johnson MM, Patel NM, Fernandez-Bussy S. Robotic-assisted bronchoscopy versus CT-guided transthoracic biopsy for diagnosis of pulmonary nodules. Respirology. 2023 01; 28(1):66-73. PMID: 36104312.
    Citations: 1     Fields:    Translation:Humans
  7. Labarca G, Sanchez-de-la Torre M, Jorquera J. Editorial: Systemic involvement in obstructive sleep apnea: Personalized medicine to improve health outcomes. Front Med (Lausanne). 2022; 9:999977. PMID: 36052334.
    Citations:    
  8. González J, Zuil M, Benítez ID, de Gonzalo-Calvo D, Aguilar M, Santisteve S, Vaca R, Minguez O, Seck F, Torres G, de Batlle J, Gómez S, Barril S, Moncusí-Moix A, Monge A, Gort-Paniello C, Ferrer R, Ceccato A, Fernández L, Motos A, Riera J, Menéndez R, Garcia-Gasulla D, Peñuelas O, Labarca G, Caballero J, Barberà C, Torres A, Barbé F. One Year Overview and Follow-Up in a Post-COVID Consultation of Critically Ill Patients. Front Med (Lausanne). 2022; 9:897990. PMID: 35911414.
    Citations: 3     
  9. Messineo L, Taranto-Montemurro L, Calianese N, Gell LK, Azarbarzin A, Labarca G, Vena D, Yang HC, Wang TY, Wellman A, Sands SA. Atomoxetine and fesoterodine combination improves obstructive sleep apnoea severity in patients with milder upper airway collapsibility. Respirology. 2022 11; 27(11):975-982. PMID: 35811347.
    Citations:    Fields:    Translation:Humans
  10. Labarca G, Sands SA, Cohn V, Demko G, Vena D, Messineo L, Gell L, Hess L, White DP, Wellman A, Azarbarzin A. Mouth Closing to Improve the Efficacy of Mandibular Advancement Devices in Sleep Apnea. Ann Am Thorac Soc. 2022 07; 19(7):1185-1192. PMID: 35254967.
    Citations:    Fields:    Translation:Humans
  11. Labarca G, Henríquez-Beltrán M, Lamperti L, Nova-Lamperti E, Sanhueza S, Cabrera C, Quiroga R, Antilef B, Ormazábal V, Zúñiga F, Castillo D, Horta G, Enos D, Lastra J, Gonzalez J, Targa A, Barbe F. Impact of Obstructive Sleep Apnea (OSA) in COVID-19 Survivors, Symptoms Changes Between 4-Months and 1 Year After the COVID-19 Infection. Front Med (Lausanne). 2022; 9:884218. PMID: 35775008.
    Citations: 3     
  12. Henríquez-Beltrán M, Labarca G, Cigarroa I, Enos D, Lastra J, Nova-Lamperti E, Targa A, Barbe F. Sleep health and the circadian rest-activity pattern four months after COVID-19. J Bras Pneumol. 2022; 48(3):e20210398. PMID: 35508066; PMCID: PMC9064633.
    Citations: 4     Fields:    Translation:Humans
  13. Benítez ID, Moncusí-Moix A, Vaca R, Gort-Paniello C, Minguez O, Santisteve S, Carmona P, Torres G, Fagotti J, Labarca G, Torres A, González J, de Gonzalo-Calvo D, Barbé F, Targa ADS. Sleep and Circadian Health of Critical COVID-19 Survivors 3 Months After Hospital Discharge. Crit Care Med. 2022 06 01; 50(6):945-954. PMID: 35234413; PMCID: PMC9112507.
    Citations: 5     Fields:    Translation:Humans
  14. González J, Benítez ID, de Gonzalo-Calvo D, Torres G, de Batlle J, Gómez S, Moncusí-Moix A, Carmona P, Santisteve S, Monge A, Gort-Paniello C, Zuil M, Cabo-Gambín R, Manzano Senra C, Vengoechea Aragoncillo JJ, Vaca R, Minguez O, Aguilar M, Ferrer R, Ceccato A, Fernández L, Motos A, Riera J, Menéndez R, Garcia-Gasulla D, Peñuelas O, Labarca G, Caballero J, Barberà C, Torres A, Barbé F. Impact of time to intubation on mortality and pulmonary sequelae in critically ill patients with COVID-19: a prospective cohort study. Crit Care. 2022 01 10; 26(1):18. PMID: 35012662.
    Citations: 13     Fields:    Translation:HumansCells
  15. Martínez-García MÁ, Labarca G. Obstructive sleep apnea in women: scientific evidence is urgently needed. J Clin Sleep Med. 2022 01 01; 18(1):1-2. PMID: 34648424; PMCID: PMC8807894.
    Citations: 1     Fields:    Translation:Humans
  16. Martínez-García MÁ, Labarca G. Corrigendum to: Sleep apnea phenotypes: do not forget the external validation. Sleep. 2021 Dec 10; 44(12). PMID: 34673979.
    Citations:    Fields:    
  17. Martínez-García MÁ, Labarca G. Sleep apnea phenotypes: do not forget the external validation. Sleep. 2021 12 10; 44(12). PMID: 34432066.
    Citations:    Fields:    Translation:Humans
  18. Hernandez PM, Enos BD, Labarca TG, Vanderstelt AG. From the Old, the Best: Parathyroidectomy in the Management of Soft-Tissue and Vascular Calcification in Patients with Chronic Renal Disease. Case Rep Nephrol. 2021; 2021:9985308. PMID: 34796031.
    Citations:    
  19. Valdivia G, Schmidt A, Schmidt B, Rivera F, Oñate A, Navarrete C, Campos J, Labarca G. Association between cardiovascular mortality and STOP-Bang questionnaire scores in a cohort of hospitalized patients: a prospective study. J Bras Pneumol. 2021; 47(4):e20210039. PMID: 34495174; PMCID: PMC8979666.
    Citations: 1     Fields:    Translation:Humans
  20. Simian D, Martínez M, Dreyse J, Chomali M, Retamal M, Labarca G. Clinical characteristics and predictors of hospitalization among 7,108 ambulatory patients with positive RT-PCR for SARS-CoV-2 during the acute pandemic period. J Bras Pneumol. 2021; 47(4):e20210131. PMID: 34495176; PMCID: PMC8979667.
    Citations: 2     Fields:    Translation:HumansCellsPHPublic Health
  21. Labarca G, Schmidt A, Dreyse J, Jorquera J, Barbe F. Telemedicine interventions for CPAP adherence in obstructive sleep apnea patients: Systematic review and meta-analysis. Sleep Med Rev. 2021 12; 60:101543. PMID: 34537668.
    Citations: 11     Fields:    Translation:Humans
  22. Yu Lee-Mateus A, Garcia-Saucedo JC, Abia-Trujillo D, Labarca G, Patel NM, Pascual JM, Fernandez-Bussy S. Comparing diagnostic sensitivity of different needle sizes for lymph nodes suspected of lung cancer in endobronchial ultrasound transbronchial needle aspiration: Systematic review and meta-analysis. Clin Respir J. 2021 Dec; 15(12):1328-1336. PMID: 34402194.
    Citations:    Fields:    Translation:Humans
  23. Labarca G, Letelier LM. Is the Systematic Review and Meta-Analysis the Gold Standard for Scientific Evidence? Arch Bronconeumol. 2022 10; 58(10):679-680. PMID: 35312600.
    Citations:    Fields:    Translation:Humans
  24. Fernandez-Bussy S, Kornafeld A, Labarca G, Abia-Trujillo D, Patel NM, Johnson MM, Reisenauer JS, Herth FJ. Risk of complications rise with coronary artery disease and diabetes mellitus after endobronchial valve placement in severe heterogeneous emphysema. Clin Respir J. 2021 Nov; 15(11):1194-1200. PMID: 34302313.
    Citations:    Fields:    Translation:Humans
  25. Labarca G, Dreyse J, Salas C, Letelier F, Jorquera J. A Validation Study of Four Different Cluster Analyses of OSA and the Incidence of Cardiovascular Mortality in a Hispanic Population. Chest. 2021 12; 160(6):2266-2274. PMID: 34217682.
    Citations: 7     Fields:    Translation:Humans
  26. Labarca G, Henríquez-Beltrán M, Lastra J, Enos D, Llerena F, Cigarroa I, Lamperti L, Ormazabal V, Ramirez C, Espejo E, Canales N, Fuentes F, Horta G, Fernandez-Bussy S, Nova-Lamperti E. Analysis of clinical symptoms, radiological changes and pulmonary function data 4 months after COVID-19. Clin Respir J. 2021 Sep; 15(9):992-1002. PMID: 34086416; PMCID: PMC8239617.
    Citations: 9     Fields:    Translation:HumansCells
  27. Fraga M, Yáñez M, Sherman M, Llerena F, Hernandez M, Nourdin G, Álvarez F, Urrizola J, Rivera C, Lamperti L, Nova L, Castro S, Zambrano O, Cifuentes A, Campos L, Moya S, Pastor J, Nuñez M, Gatica J, Figueroa J, Zúñiga F, Salomón C, Cerda G, Puentes R, Labarca G, Vidal M, McGregor R, Nova-Lamperti E. Immunomodulation of T Helper Cells by Tumor Microenvironment in Oral Cancer Is Associated With CCR8 Expression and Rapid Membrane Vitamin D Signaling Pathway. Front Immunol. 2021; 12:643298. PMID: 34025655.
    Citations: 5     Fields:    Translation:HumansCells
  28. González J, Benítez ID, Carmona P, Santisteve S, Monge A, Moncusí-Moix A, Gort-Paniello C, Pinilla L, Carratalá A, Zuil M, Ferrer R, Ceccato A, Fernández L, Motos A, Riera J, Menéndez R, Garcia-Gasulla D, Peñuelas O, Bermejo-Martin JF, Labarca G, Caballero J, Torres G, de Gonzalo-Calvo D, Torres A, Barbé F. Pulmonary Function and Radiologic Features in Survivors of Critical COVID-19: A 3-Month Prospective Cohort. Chest. 2021 07; 160(1):187-198. PMID: 33676998; PMCID: PMC7930807.
    Citations: 85     Fields:    Translation:HumansCells
  29. Enos D, Labarca G, Hernandez M, Mendez GP. Takayasu's arteritis and secondary membranous nephropathy: an exceptional association. BMJ Case Rep. 2021 Mar 01; 14(3). PMID: 33649037; PMCID: PMC7929856.
    Citations:    Fields:    Translation:Humans
  30. Horta G, Soto S, Labarca G. [Vitamin D levels in patients with inflammatory bowel disease]. Rev Med Chil. 2021 Mar; 149(3):393-398. PMID: 34479318.
    Citations: 1     Fields:    Translation:Humans
  31. Labarca G, Henriquez-Beltran M, Llerena F, Erices G, Lastra J, Enos D, Castillo D, Fraga M, Lamperti L, Ormazabal V, Riffo B, Rubilar D, Sanhueza R, Vasquez J, Villanueva C, Horta G, Sanhueza F, Melo P, Dreyse J, Jorquera J, Fernandez-Bussy S, Gonzalez J, Barbe F, Nova-Lamperti E. Undiagnosed sleep disorder breathing as a risk factor for critical COVID-19 and pulmonary consequences at the midterm follow-up. Sleep Med. 2022 03; 91:196-204. PMID: 33678579; PMCID: PMC7892300.
    Citations: 10     Fields:    Translation:HumansCells
  32. Labarca G, Schmidt A, Dreyse J, Jorquera J, Enos D, Torres G, Barbe F. Efficacy of continuous positive airway pressure (CPAP) in patients with obstructive sleep apnea (OSA) and resistant hypertension (RH): Systematic review and meta-analysis. Sleep Med Rev. 2021 08; 58:101446. PMID: 33607443.
    Citations: 9     Fields:    Translation:Humans
  33. Labarca G, Dreyse J, Salas C, Schmidt A, Rivera F, Letelier F, Jorquera J. Risk of mortality among patients with moderate to severe obstructive sleep apnea and diabetes mellitus: results from the SantOSA cohort. Sleep Breath. 2021 Sep; 25(3):1467-1475. PMID: 33394326.
    Citations: 7     Fields:    Translation:Humans
  34. Labarca G, Dreyse J, Salas C, Letelier F, Schmidt A, Rivera F, Jorquera J. Clinical utility of oximetric parameters to identify a high-risk phenotype of moderate-severe Obstructive Sleep Apnea (OSA). Clin Respir J. 2020 Dec; 14(12):1166-1175. PMID: 32780496.
    Citations: 2     Fields:    Translation:Humans
  35. Fernandez-Bussy S, Kornafeld A, Labarca G, Abia-Trujillo D, Patel NM, Herth FJF. Endoscopic Lung Volume Reduction in Relation to Body Mass Index in Patients with Severe Heterogeneous Emphysema. Respiration. 2020; 99(6):477-483. PMID: 32492686.
    Citations: 1     Fields:    Translation:Humans
  36. Folch EE, Labarca G, Ospina-Delgado D, Kheir F, Majid A, Khandhar SJ, Mehta HJ, Jantz MA, Fernandez-Bussy S. Sensitivity and Safety of Electromagnetic Navigation Bronchoscopy for Lung Cancer Diagnosis: Systematic Review and Meta-analysis. Chest. 2020 10; 158(4):1753-1769. PMID: 32450240.
    Citations: 36     Fields:    Translation:Humans
  37. Labarca G, Horta G. Obstructive sleep apnea and nonalcoholic fatty liver disease: do we need to consider this association in current clinical practice? Sleep Med. 2021 01; 77:355-356. PMID: 32564917.
    Citations: 2     Fields:    Translation:Humans
  38. Fernández-Bussy S, Sánchez O, Parikh M, Paton A, Kheir F, Chee A, Martínez R, Gando S, Lanza M, Canias A, Labarca G, Garcia MA, Dure R, Abia-Trujillo D, García AO, Rubinstein P, Oliveira H, Flandes J, Folch E, Majid A. [Recommendations for performing interventions during the COVID-19 pandemic]. Rev Med Chil. 2020 May; 148(5):689-696. PMID: 33399763.
    Citations:    Fields:    Translation:HumansPHPublic Health
  39. Labarca G, Saavedra D, Dreyse J, Jorquera J, Barbe F. Efficacy of CPAP for Improvements in Sleepiness, Cognition, Mood, and Quality of Life in Elderly Patients With OSA: Systematic Review and Meta-analysis of Randomized Controlled Trials. Chest. 2020 08; 158(2):751-764. PMID: 32289311.
    Citations: 20     Fields:    Translation:Humans
  40. Labarca G, Dreyse J, Salas C, Schmidt A, Rivera F, Letelier F, Jorquera J, Barbe F. A clinic-based cluster analysis in patients with moderate-severe obstructive sleep apnea (OSA) in Chile. Sleep Med. 2020 09; 73:16-22. PMID: 32771926.
    Citations: 3     Fields:    Translation:Humans
  41. Gower J, Labarca G, Enos D, Nova-Lamperti E. Rapid development of severe acute respiratory distress syndrome after abatacept treatment in a patient with rheumatoid arthritis. BMJ Case Rep. 2020 Apr 06; 13(4). PMID: 32265206; PMCID: PMC7244282.
    Citations:    Fields:    Translation:Humans
  42. Labarca G, Jorquera J, Dreyse J, Salas C, Letelier F. Hypoxemic features of obstructive sleep apnea and the risk of mortality: a cluster analysis. Sleep Breath. 2021 03; 25(1):95-103. PMID: 32232718.
    Citations: 5     Fields:    Translation:Humans
  43. Labarca G, Dreyse J, Drake L, Jorquera J, Barbe F. Efficacy of continuous positive airway pressure (CPAP) in the prevention of cardiovascular events in patients with obstructive sleep apnea: Systematic review and meta-analysis. Sleep Med Rev. 2020 08; 52:101312. PMID: 32248026.
    Citations: 24     Fields:    Translation:Humans
  44. Folch EE, Mahajan AK, Oberg CL, Maldonado F, Toloza E, Krimsky WS, Oh S, Bowling MR, Benzaquen S, Kinsey CM, Mehta AC, Fernandez-Bussy S, Flandes J, Lau K, Krishna G, Nead MA, Herth F, Aragaki-Nakahodo AA, Barisione E, Bansal S, Zanchi D, Zgoda M, Lutz PO, Lentz RJ, Parks C, Salio M, Perret K, Keyes C, LeMense GP, Hinze JD, Majid A, Christensen M, Kazakov J, Labarca G, Waller E, Studnicka M, Teba CV, Khandhar SJ. Standardized Definitions of Bleeding After Transbronchial Lung Biopsy: A Delphi Consensus Statement From the Nashville Working Group. Chest. 2020 07; 158(1):393-400. PMID: 32067944; PMCID: PMC7403751.
    Citations: 16     Fields:    Translation:Humans
  45. Labarca G, Uribe JP, Majid A, Folch E, Fernandez-Bussy S. [How to interpret systematic reviews with multiple comparisons or network meta-analysis]. Rev Med Chil. 2020 Jan; 148(1):109-117. PMID: 32730443.
    Citations: 1     Fields:    
  46. Valdivia G, Navarrete C, Oñate A, Schmidt B, Fuentes R, Espejo E, Enos D, Fernandez-Bussy I, Labarca G. [Association between high vitamin B12 levels and one year mortality in older people admitted to the hospital]. Rev Med Chil. 2020 Jan; 148(1):46-53. PMID: 32730435.
    Citations:    Fields:    Translation:Humans
  47. Labarca G, Dreyse J, Salas C, Gaete MI, Jorquera J. Performance of instruments aimed at detecting obstructive sleep apnea syndrome among individuals in Chile. J Bras Pneumol. 2019 12 13; 46(1):e20190015. PMID: 31851221.
    Citations: 3     Fields:    Translation:Humans
  48. Majid A, Labarca G, Uribe JP, Kheir F, Pacheco C, Folch E, Jantz MA, Mehta HJ, Patel NM, Herth FJF, Fernandez-Bussy S. Efficacy of the Spiration Valve System in Patients with Severe Heterogeneous Emphysema: A Systematic Review and Meta-Analysis. Respiration. 2020; 99(1):62-72. PMID: 31760389.
    Citations: 3     Fields:    Translation:Humans
  49. Labarca G, Gower J, Lamperti L, Dreyse J, Jorquera J. Chronic intermittent hypoxia in obstructive sleep apnea: a narrative review from pathophysiological pathways to a precision clinical approach. Sleep Breath. 2020 Jun; 24(2):751-760. PMID: 31758436.
    Citations: 29     Fields:    Translation:Humans
  50. Labarca G, Abud R. Impact of continuous positive airway pressure on glucose metabolism. Sleep Med. 2020 01; 65:149. PMID: 31862155.
    Citations: 1     Fields:    Translation:Humans
  51. Labarca G, Sierra-Ruiz M, Kheir F, Folch E, Majid A, Mehta HJ, Jantz MA, Fernandez-Bussy S. Diagnostic Accuracy of Endobronchial Ultrasound Transbronchial Needle Aspiration in Lymphoma. A Systematic Review and Meta-Analysis. Ann Am Thorac Soc. 2019 11; 16(11):1432-1439. PMID: 31291126.
    Citations: 12     Fields:    Translation:Humans
  52. Labarca G, Drake L, Horta G, Jantz MA, Mehta HJ, Fernandez-Bussy S, Folch E, Majid A, Picco M. Association between inflammatory bowel disease and chronic obstructive pulmonary disease: a systematic review and meta-analysis. BMC Pulm Med. 2019 Oct 28; 19(1):186. PMID: 31660921; PMCID: PMC6819559.
    Citations: 13     Fields:    Translation:Humans
  53. Salas C, Dreyse J, Contreras A, Nazar G, Astorquiza C, Cabezon R, Labarca G, Jorquera J. Differences in patients derived from otolaryngology and other specialties with sleep apnea. J Otolaryngol Head Neck Surg. 2019 Oct 22; 48(1):53. PMID: 31640800; PMCID: PMC6805651.
    Citations: 2     Fields:    Translation:Humans
  54. Gando S, Labarca G, Majid A, Folch E, Mehta HJ, Jantz M, Fernandez-Bussy S. [Airway tridimensional printing]. Rev Med Chil. 2019 Oct; 147(10):1315-1322. PMID: 32186640.
    Citations:    Fields:    Translation:Humans
  55. Fernandez-Bussy S, Biswas A, Labarca G, Jantz MA, Mehta HJ. Comparison of Endobronchial Ultrasound-guided Transbronchial Needle Aspiration With Stylet Retracted Partially Versus Completely for Molecular Testing. J Bronchology Interv Pulmonol. 2019 Jul; 26(3):222-224. PMID: 31107296.
    Citations: 1     Fields:    Translation:Humans
  56. Labarca G, Uribe JP, Pacheco C, Folch E, Kheir F, Majid A, Jantz MA, Mehta HJ, Patel N, Herth FJF, Fernandez-Bussy S. Bronchoscopic Lung Volume Reduction with Endobronchial Zephyr Valves for Severe Emphysema: A Systematic Review and Meta-Analysis. Respiration. 2019; 98(3):268-278. PMID: 31117102.
    Citations: 9     Fields:    Translation:Humans
  57. Labarca G, Campos J, Thibaut K, Dreyse J, Jorquera J. Do T90 and SaO2 nadir identify a different phenotype in obstructive sleep apnea? Sleep Breath. 2019 Sep; 23(3):1007-1010. PMID: 31081538.
    Citations: 11     Fields:    Translation:Humans
  58. Labarca G, Valdivia G, Oñate A, Navarrete C, Araya J, Fernandez-Bussy I, Dreyse J, Jorquera J. Prevalence of STOP BANG questionnaire and association with major cardiovascular events in hospitalized population: is it enough with currently used cardiovascular risk measurements? Sleep Med. 2019 09; 61:82-87. PMID: 31416696.
    Citations: 3     Fields:    Translation:Humans
  59. Caviedes I, Labarca G, Silva CF, Fernandez-Bussy S. Marijuana Use, Respiratory Symptoms, and Pulmonary Function. Ann Intern Med. 2019 01 15; 170(2):142. PMID: 30641566.
    Citations:    Fields:    Translation:Humans
  60. Fernandez-Bussy S, Labarca G, Herth FJF. Bronchoscopic Lung Volume Reduction in Patients with Severe Emphysema. Semin Respir Crit Care Med. 2018 Dec; 39(6):685-692. PMID: 30641586.
    Citations:    Fields:    Translation:Humans
  61. Abud R, Salgueiro M, Drake L, Reyes T, Jorquera J, Labarca G. Efficacy of continuous positive airway pressure (CPAP) preventing type 2 diabetes mellitus in patients with obstructive sleep apnea hypopnea syndrome (OSAHS) and insulin resistance: a systematic review and meta-analysis. Sleep Med. 2019 10; 62:14-21. PMID: 31518943.
    Citations: 13     Fields:    Translation:Humans
  62. Fernandez-Bussy S, Labarca G, Folch E. "Needle Aspiration" as an Occupational Injury. Arch Bronconeumol (Engl Ed). 2019 Mar; 55(3):156. PMID: 30314691.
    Citations:    Fields:    Translation:Humans
  63. Labarca G, Folch E, Jantz M, Mehta HJ, Majid A, Fernandez-Bussy S. Adequacy of Samples Obtained by Endobronchial Ultrasound with Transbronchial Needle Aspiration for Molecular Analysis in Patients with Non-Small Cell Lung Cancer. Systematic Review and Meta-Analysis. Ann Am Thorac Soc. 2018 10; 15(10):1205-1216. PMID: 30011388.
    Citations: 15     Fields:    Translation:Humans
  64. Montufar F, Moral LD, Labarca G, Folch E, Majid A, Fernandez-Bussy S. [Transbronchial cryobiopsies and cryotherapy in lung diseases]. Rev Med Chil. 2018 Sep; 146(9):1033-1040. PMID: 30725025.
    Citations: 1     Fields:    Translation:Humans
  65. Labarca G, Reyes T, Jorquera J, Dreyse J, Drake L. CPAP in patients with obstructive sleep apnea and type 2 diabetes mellitus: Systematic review and meta-analysis. Clin Respir J. 2018 Aug; 12(8):2361-2368. PMID: 30073792.
    Citations: 28     Fields:    Translation:Humans
  66. Fernandez-Bussy S, Labarca G, Majid A. Dark Airway Pigmentation in a Copper Miner. Arch Bronconeumol (Engl Ed). 2018 Dec; 54(12):628. PMID: 30049556.
    Citations:    Fields:    Translation:Humans
  67. Labarca G, Dreyse J, Salas C, Contreras A, Nazar G, Gaete MI, Jorquera J. Differences between manual and automatic analysis in determining the severity of obstructive sleep apnea using home sleep apnea testing. Sleep Med. 2018 07; 47:66-71. PMID: 29772418.
    Citations: 2     Fields:    Translation:Humans
  68. Fernandez-Bussy S, Inaty H, Caviedes I, Labarca G, Vial MR, Majid A. Unusual diagnoses made by convex-probe endobronchial ultrasound-guided transbronchial needle aspiration. Pulmonology. 2018 Sep - Oct; 24(5):300-306. PMID: 29627400.
    Citations:    Fields:    Translation:Humans
  69. Fernandez-Bussy S, Labarca G, Vial MR, Soto R, Mehta HJ, Jantz M, Majid A, Burotto M. Recurrent Respiratory Papillomatosis and Bevacizumab Treatment. Am J Respir Crit Care Med. 2018 02 15; 197(4):539-541. PMID: 28968150.
    Citations: 2     Fields:    Translation:Humans
  70. Caviedes IR, Labarca G, de Oliveira HG, Herth FJF, Fernandez-Bussy S. Non-Answered Questions in Patients with Endobronchial Valve Placement for Lung Volume Reduction. Respiration. 2018; 95(4):269-272. PMID: 29444521.
    Citations: 1     Fields:    Translation:Humans
  71. Labarca G, Cruz R, Jorquera J. Continuous Positive Airway Pressure in Patients With Obstructive Sleep Apnea and Non-Alcoholic Steatohepatitis: A Systematic Review and Meta-Analysis. J Clin Sleep Med. 2018 01 15; 14(1):133-139. PMID: 29151428.
    Citations: 10     Fields:    Translation:Humans
  72. Fernandez-Bussy S, Labarca G, de Oliveira H. Endobronchial Valve Migration Secondary to Changes in Bronchial Diameter After the Initial Treatment. J Bronchology Interv Pulmonol. 2018 01; 25(1):e7-e9. PMID: 29261587.
    Citations: 1     Fields:    Translation:Humans
  73. Fernandez-Bussy S, Labarca G, Majid A. Endoscopic Lung Volume Reduction by Endobronchial Coils: First Report From Latin America. J Bronchology Interv Pulmonol. 2018 01; 25(1):e4-e6. PMID: 29261584.
    Citations:    Fields:    Translation:Humans
  74. Fernandez-Bussy S, Pires Y, Labarca G, Vial MR. PD-L1 Expression in a Non-Small Cell Lung Cancer Specimen Obtained by EBUS-TBNA. Arch Bronconeumol (Engl Ed). 2018 May; 54(5):290-292. PMID: 29223638.
    Citations: 7     Fields:    Translation:Humans
  75. Gando S, Duré R, Violi D, Vazquez B, Labarca G, Fernandez-Bussy S. Bilateral lung disease, extensive and diffuse. Diagnosis of pulmonary alveolar proteinosis by bronchoscopic cryobiopsy. Respir Med Case Rep. 2017; 22:260-262. PMID: 29021953; PMCID: PMC5633158.
    Citations: 2     
  76. Labarca G, Caviedes I, Folch E, Majid A, Fernández-Bussy S. [Endobronchial ultrasound-guided transbronchial needle aspiration]. Rev Med Chil. 2017 Sep; 145(9):1165-1171. PMID: 29424404.
    Citations: 1     Fields:    Translation:Humans
  77. Caviedes I, Fernandez-Bussy S, Labarca G, Herth FJF. Clinical screening of oropharyngeal dysphagia: standard of care. Eur Respir J. 2017 08; 50(2). PMID: 28860270.
    Citations:    Fields:    Translation:Humans
  78. Labarca G, Bustamante A, Valdivia G, Díaz R, Huete Á, Mac Nab P, Mendoza L, Leppe J, Lisboa C, Saldías F, Díaz O. The boundaries of mild chronic obstructive pulmonary disease (COPD): design of the searching clinical COPD onset (SOON) study. BMJ Open. 2017 Aug 11; 7(8):e015731. PMID: 28801407; PMCID: PMC5724156.
    Citations: 2     Fields:    Translation:Humans
  79. Labarca G, Caviedes I, Vial MR, Pires Y, Folch E, Majid A, Fernandez-Bussy S. Airway fibroepithelial polyposis. Respir Med Case Rep. 2017; 22:154-157. PMID: 28831375; PMCID: PMC5554959.
    Citations: 1     
  80. Labarca G, Ortega F, Arenas A, Reyes T, Rada G, Jorquera J. Extrapulmonary effects of continuous airway pressure on patients with obstructive sleep apnoea: protocol for an overview of systematic reviews. BMJ Open. 2017 06 30; 7(6):e015315. PMID: 28667213.
    Citations: 1     Fields:    Translation:Humans
  81. Fernández-Bussy S, Labarca G, Caviedes I, Mehta HJ, Jantz M, Majid A. [Endoscopic lung volume reduction in advanced pulmonary emphysema: initial experience in Chile]. Rev Med Chil. 2017 May; 145(5):667-672. PMID: 28898345.
    Citations:    Fields:    Translation:Humans
  82. Jeldres A, Labarca G. Is nintedanib effective for idiopathic pulmonary fibrosis? Medwave. 2017 Apr 10; 17(Suppl2):e6918. PMID: 28430774.
    Citations: 1     Fields:    Translation:Humans
  83. Fernandez-Bussy S, Labarca G, Majid A. In reply: Biodegradable stent for vanishing bronchus syndrome after lung transplantation. J Heart Lung Transplant. 2017 05; 36(5):592. PMID: 28262439.
    Citations:    Fields:    
  84. Labarca G, Jantz MA, Mehta HJ, Folch E, Majid A, Fernandez-Bussy S. Is there added value in adding EUS to EBUS? Lancet Respir Med. 2017 02; 5(2):e8. PMID: 28145236.
    Citations:    Fields:    Translation:Humans
  85. Jeldres A, Labarca G. Is pirfenidone effective for idiopathic pulmonary fibrosis? Medwave. 2017 Jan 17; 17(Suppl1):e6843. PMID: 28112713.
    Citations: 1     Fields:    Translation:Humans
  86. Fernandez-Bussy S, Labarca G, Pires Y, Caviedes I, Burotto M. Molecular Testing of EGFR, EGFR Resistance Mutation, ALK and ROS1 Achieved by EBUS-TBNA in Chile. Arch Bronconeumol. 2017 Mar; 53(3):172-174. PMID: 27825731.
    Citations: 8     Fields:    Translation:Humans
  87. Labarca G, Aravena C, Ortega F, Arenas A, Majid A, Folch E, Mehta HJ, Jantz MA, Fernandez-Bussy S. Minimally Invasive Methods for Staging in Lung Cancer: Systematic Review and Meta-Analysis. Pulm Med. 2016; 2016:1024709. PMID: 27818796.
    Citations: 10     Fields:    Translation:Humans
  88. Fernandez-Bussy S, Labarca G, Majid A. Biodegradable stent for vanishing bronchus syndrome after lung transplantation. J Heart Lung Transplant. 2016 11; 35(11):1378-1379. PMID: 27836025.
    Citations: 1     Fields:    Translation:Humans
  89. Jeldres Pulgar A, Labarca G. Is N-acetylcysteine effective in the treatment of pulmonary fibrosis? Medwave. 2016 Sep 29; 16(Suppl3):e6555. PMID: 27689534.
    Citations: 1     Fields:    
  90. Labarca G, Ramirez R, Monsalve X, Mira-Avendano I. Dementia, gait disturbance, and urinary incontinence in a patient with pulmonary sarcoidosis. Respirol Case Rep. 2016 Sep; 4(5):e00182. PMID: 28127435.
    Citations: 4     
  91. Fernández-Bussy S, Labarca G, Lanza M, Folch E, Majid A. [A review on thoracic ultrasound]. Rev Med Chil. 2016 Jul; 144(7):903-9. PMID: 27661554.
    Citations:    Fields:    Translation:Humans
  92. Fernández-Bussy S, Labarca G, Caviedes I, Folch E, Majid A. [Endobronchial ultrasound and fine needle aspiration for central airway lesions]. Rev Med Chil. 2016 Mar; 144(3):341-6. PMID: 27299820.
    Citations:    Fields:    Translation:Humans
  93. Gando S, García A, Labarca G, Fernandez-Bussy S. A 37-Year-Old Woman with Dyspnea and Stridor. Ann Am Thorac Soc. 2016 Mar; 13(3):428-31. PMID: 26963354.
    Citations: 1     Fields:    Translation:Humans
  94. Fernández-Bussy S, Campos F, Ogueta I, Labarca G, Cabello H. [Chronic eosinophilic pneumonia: Report of one case]. Rev Med Chil. 2016 Feb; 144(2):262-6. PMID: 27092683.
    Citations:    Fields:    Translation:Humans
  95. Fernandez-Bussy S, Labarca G, Castro A, Caviedes I. Primary mediastinal small cell melanoma achieved by EBUS-TBNA. Thorax. 2016 Apr; 71(4):387. PMID: 26719227.
    Citations: 1     Fields:    Translation:Humans
  96. Aravena C, Labarca G, Venegas C, Arenas A, Rada G. Correction: Pirfenidone for Idiopathic Pulmonary Fibrosis: A Systematic Review and Meta-Analysis. PLoS One. 2015; 10(10):e0140288. PMID: 26439742.
    Citations: 4     Fields:    
  97. Fernandez-Bussy S, Antunez M, Pires Y, Labarca G. Endobronchial Involvement in Idiopathic Hypereosinophilic Syndrome. J Bronchology Interv Pulmonol. 2015 Oct; 22(4):329-31. PMID: 26492606.
    Citations:    Fields:    Translation:Humans
  98. Aravena C, Labarca G, Venegas C, Arenas A, Rada G. Pirfenidone for Idiopathic Pulmonary Fibrosis: A Systematic Review and Meta-Analysis. PLoS One. 2015; 10(8):e0136160. PMID: 26308723.
    Citations: 16     Fields:    Translation:Humans
  99. Fernandez-Bussy S, Labarca G, Rodriguez M, Mehta HJ, Jantz M. Concomitant tracheal and subcutaneous glomus tumor: Case report and review of the literature. Respir Med Case Rep. 2015; 16:81-5. PMID: 26744663; PMCID: PMC4681967.
    Citations: 7     
  100. Fernández-Bussy S, Labarca G, Canals S, Caviedes I, Folch E, Majid A. Diagnostic yield of endobronchial ultrasound-guided transbronchial needle aspiration for mediastinal staging in lung cancer. J Bras Pneumol. 2015 May-Jun; 41(3):219-24. PMID: 26176519.
    Citations: 10     Fields:    Translation:Humans
  101. Fernández-Bussy S, Labarca G, Canals S, Zagollin M, Oyonarte MM, Isamit D, Jalilie A, Guerra C, Chernilo S. [Bronchoscopy with transbronchial biopsy for the diagnosis of potentially malignant pulmonary lesions: experience in 261 patients]. Rev Med Chil. 2015 Apr; 143(4):433-8. PMID: 26204533.
    Citations: 1     Fields:    Translation:Humans
  102. Labarca G, Monsalve X. Supraclavicular mass in a patient with chronic kidney disease. BMJ Case Rep. 2014 Nov 28; 2014. PMID: 25432912.
    Citations:    Fields:    Translation:Humans
  103. Labarca G, de Grazia R, Turrillas P. [Groove sign and thickened fascia in eosinophilic fasciitis]. Med Clin (Barc). 2015 Feb 02; 144(3):143. PMID: 25441021.
    Citations:    Fields:    Translation:Humans
  104. Fernández-Bussy S, Labarca G, Caviedes I, Folch E, Majid A. Bronchial thermoplasty for severe asthma: Initial experience in Chile. Arch Bronconeumol. 2016 Jan; 52(1):52. PMID: 25446869.
    Citations: 2     Fields:    Translation:Humans
  105. Fernández-Bussy S, Labarca G, Pires Y, Díaz JC, Caviedes I. Dendriform pulmonary ossification. Respir Care. 2015 Apr; 60(4):e64-7. PMID: 25316886.
    Citations: 13     Fields:    Translation:Humans
  106. Rey D, Labarca G, Caviedes I, Fernandez-Bussy S. Intracardiac metastasis of lung adenocarcinoma diagnosed by convex-probe EBUS. BMJ Case Rep. 2014 Sep 29; 2014. PMID: 25267811.
    Citations: 1     Fields:    Translation:Humans
  107. Fernandez-Bussy S, Labarca G, Descalzi F, Pires Y, Santos M, Folch E, Majid A. Endobronchial chondromas. Respir Care. 2014 Dec; 59(12):e193-6. PMID: 25233382.
    Citations: 6     Fields:    Translation:Humans
  108. Labarca G, Cruz N R, Descalzi F. [Multisystemic involvement in obstructive sleep apnea]. Rev Med Chil. 2014 Jun; 142(6):748-57. PMID: 25327320.
    Citations: 8     Fields:    Translation:Humans
  109. Fernández-Bussy S, Labarca G, Zagolin M, Oyonarte M, Isamit D, Jalilie A, Guerra C, Chernilo S. [Immediate complications following flexible bronchoscopy: retrospective analysis of 1079 procedures]. Rev Med Chil. 2014 Mar; 142(3):299-304. PMID: 25052266.
    Citations: 6     Fields:    Translation:Humans
  110. Cabello H, Labarca G, Fernández-Bussy S, Cabello F, Pires Y, Soto R, Thompson L. [Treatment failure in community-acquired pneumonia: coccidioidomycosis in a traveler patient]. Rev Chilena Infectol. 2013 Dec; 30(6):669-72. PMID: 24522314.
    Citations:    Fields:    Translation:Humans
  111. Labarca G, Cabello H, Fernández Bussy S, Cabello F, Díaz JC. A case of interstitial lung disease with apical pleural thickening: idiopathic pleuroparenchymal fibroelastosis. Arch Bronconeumol. 2014 Jan; 50(1):48-9. PMID: 24139332.
    Citations: 1     Fields:    Translation:Humans
  112. Fernández-Bussy S, Labarca G, Folch E, Majid A. Extramedullary endobronchial plasmacytoma. BMJ Case Rep. 2013 Jan 09; 2013. PMID: 23307453.
    Citations: 1     Fields:    Translation:Humans
  113. Fernandez-Bussy S, Labarca G, Cabello F, Cabello H, Folch E, Majid A. Sweet's syndrome with pulmonary involvement: Case report and literature review. Respir Med Case Rep. 2012; 6:16-9. PMID: 26029596; PMCID: PMC3920571.
    Citations: 7     
  114. Fernández P, Labarca G. [Cystic fibrosis in adults: experience of a national reference center]. Rev Med Chil. 2012 Jul; 140(7):841-6. PMID: 23282694.
    Citations:    Fields:    Translation:Humans
  115. Ortiz C, Wagner E, Mocoçain P, Labarca G, Keller A, Del Buono A, Maffulli N. Biomechanical comparison of four methods of repair of the Achilles tendon: a laboratory study with bovine tendons. J Bone Joint Surg Br. 2012 May; 94(5):663-7. PMID: 22529088.
    Citations: 12     Fields:    Translation:Animals
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.