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Iannis Adamopoulos, D.Phil.

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Biography
education and training
University Of Oxford, Oxford, UKD.Phil09/2006Immunology
Washington University of St LouisPost-doc09/2007Immunology
DNAX Research Institute, Palo Alto, CAPost-doc12/2010Immunology

Overview

Research
research activities and funding
The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
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  1. R01AR068974 (ADAMOPOULOS, IANNIS ELIAS) Jul 22, 2016 - Aug 31, 2022
    NIH
    Role of splicing factor SRSF1 in T cell function and autoimmunity
    Role: Principal investigator
  2. R01AR062173 (ADAMOPOULOS, IANNIS ELIAS) Apr 1, 2012 - Nov 30, 2024
    NIH
    The IL-23/IL-17 Axis in Inflammatory Arthritis
    Role: Principal Investigator

Bibliographic
selected publications
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Furuya H, Nguyen CT, Gu R, Hsieh SL, Maverakis E, Adamopoulos IE. IL-23 regulates inflammatory osteoclastogenesis via the activation of MDL-1+ osteoclast precursors. Arthritis Rheumatol. 2023 Feb 14. PMID: 36787107.
    Citations:    Fields:    
  2. Marusina AI, Ji-Xu A, Le ST, Toussi A, Tsoi LC, Li Q, Luxardi G, Nava J, Downing L, Leal AR, Kuzminykh NY, Kruglinskaya O, Brüggen MC, Adamopoulos IE, Merleev AA, Gudjonsson JE, Maverakis E. Cell-Specific, Disease-Associated and Variant-Linked Alterations In Expression Of ERAP1, ERAP2 and LNPEP Aminopeptidases. J Invest Dermatol. 2023 Jan 27. PMID: 36716917.
    Citations:    Fields:    
  3. Merleev A, Ji-Xu A, Toussi A, Tsoi LC, Le ST, Luxardi G, Xing X, Wasikowski R, Liakos W, Brüggen MC, Elder JT, Adamopoulos IE, Izumiya Y, Leal AR, Li Q, Kuzminykh NY, Kirane A, Marusina AI, Gudjonsson JE, Maverakis E. Proprotein convertase subtilisin/kexin type 9 is a psoriasis-susceptibility locus that is negatively related to IL36G. JCI Insight. 2022 08 22; 7(16). PMID: 35862195; PMCID: PMC9462487.
    Citations:    Fields:    
  4. Merleev AA, Le ST, Alexanian C, Toussi A, Xie Y, Marusina AI, Watkins SM, Patel F, Billi AC, Wiedemann J, Izumiya Y, Kumar A, Uppala R, Kahlenberg JM, Liu FT, Adamopoulos IE, Wang EA, Ma C, Cheng MY, Xiong H, Kirane A, Luxardi G, Andersen B, Tsoi LC, Lebrilla CB, Gudjonsson JE, Maverakis E. Biogeographic and disease-specific alterations in epidermal lipid composition and single-cell analysis of acral keratinocytes. JCI Insight. 2022 08 22; 7(16). PMID: 35900871; PMCID: PMC9462509.
    Citations:    Fields:    
  5. Nguyen CT, Furuya H, Das D, Marusina AI, Merleev AA, Ravindran R, Jalali Z, Khan IH, Maverakis E, Adamopoulos IE. Peripheral ?d T Cells Regulate Neutrophil Expansion and Recruitment in Experimental Psoriatic Arthritis. Arthritis Rheumatol. 2022 09; 74(9):1524-1534. PMID: 35320625; PMCID: PMC9427669.
    Citations:    Fields:    
  6. Su S, Katopodi XL, Pita-Juarez YH, Maverakis E, Vlachos IS, Adamopoulos IE. Serine and arginine rich splicing factor 1 deficiency alters pathways involved in IL-17A expression and is implicated in human psoriasis. Clin Immunol. 2022 07; 240:109041. PMID: 35613697.
    Citations:    Fields:    Translation:HumansAnimalsCells
  7. Li H, Tsokos MG, Bhargava R, Adamopoulos IE, Menn-Josephy H, Stillman IE, Rosenstiel P, Jordan J, Tsokos GC. IL-23 reshapes kidney resident cell metabolism and promotes local kidney inflammation. J Clin Invest. 2021 06 15; 131(12). PMID: 33956666; PMCID: PMC8203450.
    Citations: 6     Fields:    Translation:HumansAnimalsCells
  8. Baeten D, Adamopoulos IE. IL-23 Inhibition in Ankylosing Spondylitis: Where Did It Go Wrong? Front Immunol. 2020; 11:623874. PMID: 33679714.
    Citations: 3     Fields:    Translation:HumansCells
  9. Klionsky DJ, Abdel-Aziz AK, Abdelfatah S, Abdellatif M, Abdoli A, Abel S, Abeliovich H, Abildgaard MH, Abudu YP, Acevedo-Arozena A, Adamopoulos IE, Adeli K, Adolph TE, Adornetto A, Aflaki E, Agam G, Agarwal A, Aggarwal BB, Agnello M, Agostinis P, Agrewala JN, Agrotis A, Aguilar PV, Ahmad ST, Ahmed ZM, Ahumada-Castro U, Aits S, Aizawa S, Akkoc Y, Akoumianaki T, Akpinar HA, Al-Abd AM, Al-Akra L, Al-Gharaibeh A, Alaoui-Jamali MA, Alberti S, Alcocer-Gómez E, Alessandri C, Ali M, Alim Al-Bari MA, Aliwaini S, Alizadeh J, Almacellas E, Almasan A, Alonso A, Alonso GD, Altan-Bonnet N, Altieri DC, Álvarez ÉMC, Alves S, Alves da Costa C, Alzaharna MM, Amadio M, Amantini C, Amaral C, Ambrosio S, Amer AO, Ammanathan V, An Z, Andersen SU, Andrabi SA, Andrade-Silva M, Andres AM, Angelini S, Ann D, Anozie UC, Ansari MY, Antas P, Antebi A, Antón Z, Anwar T, Apetoh L, Apostolova N, Araki T, Araki Y, Arasaki K, Araújo WL, Araya J, Arden C, Arévalo MA, Arguelles S, Arias E, Arikkath J, Arimoto H, Ariosa AR, Armstrong-James D, Arnauné-Pelloquin L, Aroca A, Arroyo DS, Arsov I, Artero R, Asaro DML, Aschner M, Ashrafizadeh M, Ashur-Fabian O, Atanasov AG, Au AK, Auberger P, Auner HW, Aurelian L, Autelli R, Avagliano L, Ávalos Y, Aveic S, Aveleira CA, Avin-Wittenberg T, Aydin Y, Ayton S, Ayyadevara S, Azzopardi M, Baba M, Backer JM, Backues SK, Bae DH, Bae ON, Bae SH, Baehrecke EH, Baek A, Baek SH, Baek SH, Bagetta G, Bagniewska-Zadworna A, Bai H, Bai J, Bai X, Bai Y, Bairagi N, Baksi S, Balbi T, Baldari CT, Balduini W, Ballabio A, Ballester M, Balazadeh S, Balzan R, Bandopadhyay R, Banerjee S, Banerjee S, Bánréti Á, Bao Y, Baptista MS, Baracca A, Barbati C, Bargiela A, Barilà D, Barlow PG, Barmada SJ, Barreiro E, Barreto GE, Bartek J, Bartel B, Bartolome A, Barve GR, Basagoudanavar SH, Bassham DC, Bast RC, Basu A, Batoko H, Batten I, Baulieu EE, Baumgarner BL, Bayry J, Beale R, Beau I, Beaumatin F, Bechara LRG, Beck GR, Beers MF, Begun J, Behrends C, Behrens GMN, Bei R, Bejarano E, Bel S, Behl C, Belaid A, Belgareh-Touzé N, Bellarosa C, Belleudi F, Belló Pérez M, Bello-Morales R, Beltran JSO, Beltran S, Benbrook DM, Bendorius M, Benitez BA, Benito-Cuesta I, Bensalem J, Berchtold MW, Berezowska S, Bergamaschi D, Bergami M, Bergmann A, Berliocchi L, Berlioz-Torrent C, Bernard A, Berthoux L, Besirli CG, Besteiro S, Betin VM, Beyaert R, Bezbradica JS, Bhaskar K, Bhatia-Kissova I, Bhattacharya R, Bhattacharya S, Bhattacharyya S, Bhuiyan MS, Bhutia SK, Bi L, Bi X, Biden TJ, Bijian K, Billes VA, Binart N, Bincoletto C, Birgisdottir AB, Bjorkoy G, Blanco G, Blas-Garcia A, Blasiak J, Blomgran R, Blomgren K, Blum JS, Boada-Romero E, Boban M, Boesze-Battaglia K, Boeuf P, Boland B, Bomont P, Bonaldo P, Bonam SR, Bonfili L, Bonifacino JS, Boone BA, Bootman MD, Bordi M, Borner C, Bornhauser BC, Borthakur G, Bosch J, Bose S, Botana LM, Botas J, Boulanger CM, Boulton ME, Bourdenx M, Bourgeois B, Bourke NM, Bousquet G, Boya P, Bozhkov PV, Bozi LHM, Bozkurt TO, Brackney DE, Brandts CH, Braun RJ, Braus GH, Bravo-Sagua R, Bravo-San Pedro JM, Brest P, Bringer MA, Briones-Herrera A, Broaddus VC, Brodersen P, Brodsky JL, Brody SL, Bronson PG, Bronstein JM, Brown CN, Brown RE, Brum PC, Brumell JH, Brunetti-Pierri N, Bruno D, Bryson-Richardson RJ, Bucci C, Buchrieser C, Bueno M, Buitrago-Molina LE, Buraschi S, Buch S, Buchan JR, Buckingham EM, Budak H, Budini M, Bultynck G, Burada F, Burgoyne JR, Burón MI, Bustos V, Büttner S, Butturini E, Byrd A, Cabas I, Cabrera-Benitez S, Cadwell K, Cai J, Cai L, Cai Q, Cairó M, Calbet JA, Caldwell GA, Caldwell KA, Call JA, Calvani R, Calvo AC, Calvo-Rubio Barrera M, Camara NO, Camonis JH, Camougrand N, Campanella M, Campbell EM, Campbell-Valois FX, Campello S, Campesi I, Campos JC, Camuzard O, Cancino J, Candido de Almeida D, Canesi L, Caniggia I, Canonico B, Cantí C, Cao B, Caraglia M, Caramés B, Carchman EH, Cardenal-Muñoz E, Cardenas C, Cardenas L, Cardoso SM, Carew JS, Carle GF, Carleton G, Carloni S, et al. Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1. Autophagy. 2021 Jan; 17(1):1-382. PMID: 33634751; PMCID: PMC7996087.
    Citations: 357     Fields:    Translation:HumansAnimalsCells
  10. Menter A, Krueger GG, Paek SY, Kivelevitch D, Adamopoulos IE, Langley RG. Interleukin-17 and Interleukin-23: A Narrative Review of Mechanisms of Action in Psoriasis and Associated Comorbidities. Dermatol Ther (Heidelb). 2021 Apr; 11(2):385-400. PMID: 33512665; PMCID: PMC8019008.
    Citations: 5     
  11. Ritchlin C, Adamopoulos IE. Axial spondyloarthritis: new advances in diagnosis and management. BMJ. 2021 01 04; 372:m4447. PMID: 33397652.
    Citations: 16     Fields:    Translation:Humans
  12. Fukui T, Yik JHN, Doyran B, Davis J, Haudenschild AK, Adamopoulos IE, Han L, Haudenschild DR. Bromodomain-containing-protein-4 and cyclin-dependent-kinase-9 inhibitors interact synergistically in vitro and combined treatment reduces post-traumatic osteoarthritis severity in mice. Osteoarthritis Cartilage. 2021 01; 29(1):68-77. PMID: 33164842.
    Citations: 3     Fields:    Translation:HumansAnimalsCells
  13. Merleev AA, Park D, Xie Y, Kailemia MJ, Xu G, Ruhaak LR, Kim K, Hong Q, Li Q, Patel F, Wan YY, Marusina AI, Adamopoulos IE, Lal NN, Mitra A, Le ST, Shimoda M, Luxardi G, Lebrilla CB, Maverakis E. A site-specific map of the human plasma glycome and its age and gender-associated alterations. Sci Rep. 2020 10 15; 10(1):17505. PMID: 33060657.
    Citations: 5     Fields:    Translation:HumansCells
  14. Bell S, Nahle Z, Adamopoulos IE. Psoriatic arthritis; overcoming the challenges by creating opportunities. Clin Immunol. 2020 09; 218:108519. PMID: 32621978.
    Citations: 1     Fields:    Translation:Humans
  15. Dai H, Adamopoulos IE. Psoriatic arthritis under the influence of IFN?. Clin Immunol. 2020 09; 218:108513. PMID: 32574710.
    Citations: 3     Fields:    Translation:HumansAnimals
  16. Li H, Adamopoulos IE, Moulton VR, Stillman IE, Herbert Z, Moon JJ, Sharabi A, Krishfield S, Tsokos MG, Tsokos GC. Systemic lupus erythematosus favors the generation of IL-17 producing double negative T cells. Nat Commun. 2020 06 05; 11(1):2859. PMID: 32503973.
    Citations: 25     Fields:    Translation:HumansAnimalsCells
  17. Toussi A, Merleev A, Barton VR, Le ST, Marusina A, Luxardi G, Kirma J, Xing X, Adamopoulos IE, Fung MA, Raychaudhuri SP, Shimoda M, Gudjonsson JE, Maverakis E. Transcriptome mining and B cell depletion support a role for B cells in psoriasis pathophysiology. J Dermatol Sci. 2019 Dec; 96(3):181-184. PMID: 31780313.
    Citations: 1     Fields:    Translation:HumansCells
  18. Nguyen CT, Maverakis E, Eberl M, Adamopoulos IE. ?d T cells in rheumatic diseases: from fundamental mechanisms to autoimmunity. Semin Immunopathol. 2019 09; 41(5):595-605. PMID: 31506867.
    Citations: 5     Fields:    Translation:HumansAnimalsCells
  19. Le ST, Merleev AA, Luxardi G, Shimoda M, Adamopoulos IE, Tsoi LC, Wang JZ, Alexanian C, Raychaudhuri SP, Hwang ST, Gudjonsson J, Marusina AI, Maverakis E. 2D Visualization of the Psoriasis Transcriptome Fails to Support the Existence of Dual-Secreting IL-17A/IL-22 Th17 T Cells. Front Immunol. 2019; 10:589. PMID: 31019502.
    Citations: 5     Fields:    Translation:HumansCells
  20. Kim KJ, Kim M, Adamopoulos IE, Tagkopoulos I. Compendium of synovial signatures identifies pathologic characteristics for predicting treatment response in rheumatoid arthritis patients. Clin Immunol. 2019 05; 202:1-10. PMID: 30831253.
    Citations: 8     Fields:    Translation:HumansCells
  21. Adamopoulos IE. Interleukin-17A and Pathologic New Bone Formation: The Myth of Prometheus Revisited. Arthritis Rheumatol. 2019 04; 71(4):483-485. PMID: 30663867; PMCID: PMC6438746.
    Citations:    Fields:    Translation:Humans
  22. Ritchlin C, Adamopoulos IE. Go with the flow-hidden vascular passages in bone. Nat Metab. 2019 Feb; 1(2):173-174. PMID: 31693001; PMCID: PMC6831092.
    Citations: 1     Fields:    
  23. Nguyen CT, Bloch Y, Skladanowska K, Savvides SN, Adamopoulos IE. Pathophysiology and inhibition of IL-23 signaling in psoriatic arthritis: A molecular insight. Clin Immunol. 2019 09; 206:15-22. PMID: 30196070; PMCID: PMC6401348.
    Citations: 7     Fields:    Translation:HumansCells
  24. Merleev AA, Marusina AI, Ma C, Elder JT, Tsoi LC, Raychaudhuri SP, Weidinger S, Wang EA, Adamopoulos IE, Luxardi G, Gudjonsson JE, Shimoda M, Maverakis E. Meta-analysis of RNA sequencing datasets reveals an association between TRAJ23, psoriasis, and IL-17A. JCI Insight. 2018 07 12; 3(13). PMID: 29997305.
    Citations: 10     Fields:    Translation:HumansAnimals
  25. Bouchareychas L, Grössinger EM, Kang M, Adamopoulos IE. ?dTCR regulates production of interleukin-27 by neutrophils and attenuates inflammatory arthritis. Sci Rep. 2018 05 15; 8(1):7590. PMID: 29765156; PMCID: PMC5954154.
    Citations: 7     Fields:    Translation:AnimalsCells
  26. Adamopoulos IE. Inflammation in bone physiology and pathology. Curr Opin Rheumatol. 2018 Jan; 30(1):59-64. PMID: 29016371.
    Citations: 39     Fields:    Translation:HumansAnimalsCells
  27. Bloch Y, Bouchareychas L, Merceron R, Skladanowska K, Van den Bossche L, Detry S, Govindarajan S, Elewaut D, Haerynck F, Dullaers M, Adamopoulos IE, Savvides SN. Structural Activation of Pro-inflammatory Human Cytokine IL-23 by Cognate IL-23 Receptor Enables Recruitment of the Shared Receptor IL-12Rß1. Immunity. 2018 01 16; 48(1):45-58.e6. PMID: 29287995.
    Citations: 47     Fields:    Translation:HumansAnimalsCells
  28. Grössinger EM, Kang M, Bouchareychas L, Sarin R, Haudenschild DR, Borodinsky LN, Adamopoulos IE. Ca2+-Dependent Regulation of NFATc1 via KCa3.1 in Inflammatory Osteoclastogenesis. J Immunol. 2018 01 15; 200(2):749-757. PMID: 29246953; PMCID: PMC5815326.
    Citations: 12     Fields:    Translation:AnimalsCells
  29. Wang EA, Suzuki E, Maverakis E, Adamopoulos IE. Targeting IL-17 in psoriatic arthritis. Eur J Rheumatol. 2017 Dec; 4(4):272-277. PMID: 29308283; PMCID: PMC5741341.
    Citations: 14     
  30. Wu DJ, Gu R, Sarin R, Zavodovskaya R, Chen CP, Christiansen BA, Zarbalis KS, Adamopoulos IE. Corrigendum to "Autophagy-linked FYVE containing protein WDFY3 interacts with TRAF6 and modulates RANKL-induced osteoclastogenesis" [J. Autoimmun. 73C (2016) 73-84]. J Autoimmun. 2017 11; 84:132. PMID: 28757133.
    Citations:    Fields:    
  31. Fierro FA, Nolta JA, Adamopoulos IE. Concise Review: Stem Cells in Osteoimmunology. Stem Cells. 2017 06; 35(6):1461-1467. PMID: 28390147.
    Citations: 20     Fields:    Translation:HumansAnimalsCells
  32. Wu DJ, Adamopoulos IE. Loss of WDFY3 ameliorates severity of serum transfer-induced arthritis independently of autophagy. Cell Immunol. 2017 06; 316:61-69. PMID: 28449847; PMCID: PMC5515728.
    Citations: 1     Fields:    Translation:AnimalsCells
  33. Wu DJ, Adamopoulos IE. Autophagy and autoimmunity. Clin Immunol. 2017 03; 176:55-62. PMID: 28095319; PMCID: PMC5346336.
    Citations: 35     Fields:    Translation:HumansAnimals
  34. Bouchareychas L, Grössinger EM, Kang M, Qiu H, Adamopoulos IE. Critical Role of LTB4/BLT1 in IL-23-Induced Synovial Inflammation and Osteoclastogenesis via NF-?B. J Immunol. 2017 01 01; 198(1):452-460. PMID: 27895169; PMCID: PMC5173389.
    Citations: 20     Fields:    Translation:AnimalsCells
  35. Marusina AI, Ono Y, Merleev AA, Shimoda M, Ogawa H, Wang EA, Kondo K, Olney L, Luxardi G, Miyamura Y, Yilma TD, Villalobos IB, Bergstrom JW, Kronenberg DG, Soulika AM, Adamopoulos IE, Maverakis E. CD4+ virtual memory: Antigen-inexperienced T cells reside in the naïve, regulatory, and memory T cell compartments at similar frequencies, implications for autoimmunity. J Autoimmun. 2017 02; 77:76-88. PMID: 27894837; PMCID: PMC6066671.
    Citations: 12     Fields:    Translation:AnimalsCells
  36. Suzuki E, Maverakis E, Sarin R, Bouchareychas L, Kuchroo VK, Nestle FO, Adamopoulos IE. T Cell-Independent Mechanisms Associated with Neutrophil Extracellular Trap Formation and Selective Autophagy in IL-17A-Mediated Epidermal Hyperplasia. J Immunol. 2016 12 01; 197(11):4403-4412. PMID: 27798153; PMCID: PMC5123839.
    Citations: 15     Fields:    Translation:AnimalsCells
  37. Sukhov A, Adamopoulos IE, Maverakis E. Interactions of the Immune System with Skin and Bone Tissue in Psoriatic Arthritis: A Comprehensive Review. Clin Rev Allergy Immunol. 2016 Aug; 51(1):87-99. PMID: 26780035.
    Citations: 12     Fields:    Translation:HumansAnimals
  38. Wu DJ, Gu R, Sarin R, Zavodovskaya R, Chen CP, Christiansen BA, Adamopoulos IE. Autophagy-linked FYVE containing protein WDFY3 interacts with TRAF6 and modulates RANKL-induced osteoclastogenesis. J Autoimmun. 2016 09; 73:73-84. PMID: 27330028; PMCID: PMC5003737.
    Citations: 10     Fields:    Translation:AnimalsCells
  39. Jiménez-Dalmaroni MJ, Gerswhin ME, Adamopoulos IE. The critical role of toll-like receptors--From microbial recognition to autoimmunity: A comprehensive review. Autoimmun Rev. 2016 Jan; 15(1):1-8. PMID: 26299984.
    Citations: 95     Fields:    Translation:HumansAnimalsCells
  40. Adamopoulos IE. Autoimmune or Autoiflammatory? Bad to the Bone. Int J Clin Rheumtol. 2015; 10(1):5-7. PMID: 26388947; PMCID: PMC4570489.
    Citations: 2     
  41. Dixit N, Wu DJ, Belgacem YH, Borodinsky LN, Gershwin ME, Adamopoulos IE. Leukotriene B4 activates intracellular calcium and augments human osteoclastogenesis. Arthritis Res Ther. 2014 Dec 02; 16(6):496. PMID: 25443625; PMCID: PMC4276054.
    Citations: 7     Fields:    Translation:HumansCells
  42. Shin HS, Sarin R, Dixit N, Wu J, Gershwin E, Bowman EP, Adamopoulos IE. Crosstalk among IL-23 and DNAX activating protein of 12 kDa-dependent pathways promotes osteoclastogenesis. J Immunol. 2015 Jan 01; 194(1):316-24. PMID: 25452564; PMCID: PMC4272876.
    Citations: 17     Fields:    Translation:HumansCells
  43. Adamopoulos IE, Mellins ED. Alternative pathways of osteoclastogenesis in inflammatory arthritis. Nat Rev Rheumatol. 2015 Mar; 11(3):189-94. PMID: 25422000.
    Citations: 47     Fields:    Translation:HumansAnimalsCells
  44. Norman GL, Yang CY, Ostendorff HP, Shums Z, Lim MJ, Wang J, Awad A, Hirschfield GM, Milkiewicz P, Bloch DB, Rothschild KJ, Bowlus CL, Adamopoulos IE, Leung PS, Janssen HJ, Cheung AC, Coltescu C, Gershwin ME. Anti-kelch-like 12 and anti-hexokinase 1: novel autoantibodies in primary biliary cirrhosis. Liver Int. 2015 Feb; 35(2):642-51. PMID: 25243383.
    Citations: 27     Fields:    Translation:HumansCTClinical Trials
  45. Orosco LA, Ross AP, Cates SL, Scott SE, Wu D, Sohn J, Pleasure D, Pleasure SJ, Adamopoulos IE, Zarbalis KS. Loss of Wdfy3 in mice alters cerebral cortical neurogenesis reflecting aspects of the autism pathology. Nat Commun. 2014 Sep 08; 5:4692. PMID: 25198012.
    Citations: 44     Fields:    Translation:Animals
  46. Wu DJ, Dixit N, Suzuki E, Nguyen T, Shin HS, Davis J, Maverakis E, Adamopoulos IE. A novel in vivo gene transfer technique and in vitro cell based assays for the study of bone loss in musculoskeletal disorders. J Vis Exp. 2014 Jun 08; (88). PMID: 24961167.
    Citations: 3     Fields:    Translation:HumansAnimalsCells
  47. Adamopoulos IE, Suzuki E, Chao CC, Gorman D, Adda S, Maverakis E, Zarbalis K, Geissler R, Asio A, Blumenschein WM, Mcclanahan T, De Waal Malefyt R, Gershwin ME, Bowman EP. IL-17A gene transfer induces bone loss and epidermal hyperplasia associated with psoriatic arthritis. Ann Rheum Dis. 2015 Jun; 74(6):1284-92. PMID: 24567524.
    Citations: 38     Fields:    Translation:AnimalsCells
  48. Suzuki E, Mellins ED, Gershwin ME, Nestle FO, Adamopoulos IE. The IL-23/IL-17 axis in psoriatic arthritis. Autoimmun Rev. 2014 Apr-May; 13(4-5):496-502. PMID: 24424175; PMCID: PMC3995976.
    Citations: 40     Fields:    Translation:HumansAnimalsCells
  49. Patel F, Marusina AI, Duong C, Adamopoulos IE, Maverakis E. NKG2C, HLA-E and their association with psoriasis. Exp Dermatol. 2013 Dec; 22(12):797-9. PMID: 24279916.
    Citations: 7     Fields:    Translation:HumansCells
  50. Yang CY, Leung PS, Adamopoulos IE, Gershwin ME. The implication of vitamin D and autoimmunity: a comprehensive review. Clin Rev Allergy Immunol. 2013 Oct; 45(2):217-26. PMID: 23359064.
    Citations: 93     Fields:    Translation:HumansAnimalsCells
  51. Ross AP, Mansilla MA, Choe Y, Helminski S, Sturm R, Maute RL, May SR, Hozyasz KK, Wójcicki P, Mostowska A, Davidson B, Adamopoulos IE, Pleasure SJ, Murray JC, Zarbalis KS. A mutation in mouse Pak1ip1 causes orofacial clefting while human PAK1IP1 maps to 6p24 translocation breaking points associated with orofacial clefting. PLoS One. 2013; 8(7):e69333. PMID: 23935987.
    Citations: 6     Fields:    Translation:HumansAnimalsCells
  52. Adamopoulos IE, Pflanz S. The emerging role of Interleukin 27 in inflammatory arthritis and bone destruction. Cytokine Growth Factor Rev. 2013 Apr; 24(2):115-21. PMID: 23165310.
    Citations: 11     Fields:    Translation:HumansAnimalsCells
  53. Dickerson TJ, Suzuki E, Stanecki C, Shin HS, Qui H, Adamopoulos IE. Rheumatoid and pyrophosphate arthritis synovial fibroblasts induce osteoclastogenesis independently of RANKL, TNF and IL-6. J Autoimmun. 2012 Dec; 39(4):369-76. PMID: 22867712.
    Citations: 11     Fields:    Translation:HumansCells
  54. Adamopoulos IE, Tessmer M, Chao CC, Adda S, Gorman D, Petro M, Chou CC, Pierce RH, Yao W, Lane NE, Laface D, Bowman EP. IL-23 is critical for induction of arthritis, osteoclast formation, and maintenance of bone mass. J Immunol. 2011 Jul 15; 187(2):951-9. PMID: 21670317; PMCID: PMC3896980.
    Citations: 66     Fields:    Translation:HumansAnimalsCells
  55. Chao CC, Chen SJ, Adamopoulos IE, Davis N, Hong K, Vu A, Kwan S, Fayadat-Dilman L, Asio A, Bowman EP. Anti-IL-17A therapy protects against bone erosion in experimental models of rheumatoid arthritis. Autoimmunity. 2011 May; 44(3):243-52. PMID: 20925596.
    Citations: 21     Fields:    Translation:Animals
  56. Chao CC, Chen SJ, Adamopoulos IE, Judo M, Asio A, Ayanoglu G, Bowman EP. Structural, cellular, and molecular evaluation of bone erosion in experimental models of rheumatoid arthritis: assessment by µCT, histology, and serum biomarkers. Autoimmunity. 2010 Dec; 43(8):642-53. PMID: 20380588.
    Citations: 5     Fields:    Translation:Animals
  57. Joyce-Shaikh B, Bigler ME, Chao CC, Murphy EE, Blumenschein WM, Adamopoulos IE, Heyworth PG, Antonenko S, Bowman EP, McClanahan TK, Phillips JH, Cua DJ. Myeloid DAP12-associating lectin (MDL)-1 regulates synovial inflammation and bone erosion associated with autoimmune arthritis. J Exp Med. 2010 Mar 15; 207(3):579-89. PMID: 20212065; PMCID: PMC2839155.
    Citations: 35     Fields:    Translation:HumansAnimalsCells
  58. Adamopoulos IE, Chao CC, Geissler R, Laface D, Blumenschein W, Iwakura Y, McClanahan T, Bowman EP. Interleukin-17A upregulates receptor activator of NF-kappaB on osteoclast precursors. Arthritis Res Ther. 2010; 12(1):R29. PMID: 20167120.
    Citations: 115     Fields:    Translation:HumansAnimalsCells
  59. Adamopoulos IE, Bowman EP. Immune regulation of bone loss by Th17 cells. Arthritis Res Ther. 2008; 10(5):225. PMID: 18983698; PMCID: PMC2592787.
    Citations: 31     Fields:    Translation:HumansAnimalsCells
  60. Harney SM, Vilariño-Güell C, Adamopoulos IE, Sims AM, Lawrence RW, Cardon LR, Newton JL, Meisel C, Pointon JJ, Darke C, Athanasou N, Wordsworth BP, Brown MA. Fine mapping of the MHC Class III region demonstrates association of AIF1 and rheumatoid arthritis. Rheumatology (Oxford). 2008 Dec; 47(12):1761-7. PMID: 18835879.
    Citations: 18     Fields:    Translation:Humans
  61. Lau YS, Adamopoulos IE, Sabokbar A, Giele H, Gibbons CL, Athanasou NA. Cellular and humoral mechanisms of osteoclast formation in Ewing's sarcoma. Br J Cancer. 2007 Jun 04; 96(11):1716-22. PMID: 17533390.
    Citations: 16     Fields:    Translation:HumansCells
  62. Xia Z, Huang Y, Adamopoulos IE, Walpole A, Triffitt JT, Cui Z. Macrophage-mediated biodegradation of poly(DL-lactide-co-glycolide) in vitro. J Biomed Mater Res A. 2006 Dec 01; 79(3):582-90. PMID: 16817218.
    Citations: 5     Fields:    Translation:AnimalsCells
  63. Adamopoulos IE, Xia Z, Lau YS, Athanasou NA. Hepatocyte growth factor can substitute for M-CSF to support osteoclastogenesis. Biochem Biophys Res Commun. 2006 Nov 17; 350(2):478-83. PMID: 17022947.
    Citations: 18     Fields:    Translation:HumansCells
  64. Adamopoulos IE, Wordsworth PB, Edwards JR, Ferguson DJ, Athanasou NA. Osteoclast differentiation and bone resorption in multicentric reticulohistiocytosis. Hum Pathol. 2006 Sep; 37(9):1176-85. PMID: 16938523.
    Citations: 8     Fields:    Translation:HumansCells
  65. Xia Z, Grover LM, Huang Y, Adamopoulos IE, Gbureck U, Triffitt JT, Shelton RM, Barralet JE. In vitro biodegradation of three brushite calcium phosphate cements by a macrophage cell-line. Biomaterials. 2006 Sep; 27(26):4557-65. PMID: 16720039.
    Citations: 15     Fields:    Translation:AnimalsCellsPHPublic Health
  66. Edwards JR, Sun SG, Locklin R, Shipman CM, Adamopoulos IE, Athanasou NA, Sabokbar A. LIGHT (TNFSF14), a novel mediator of bone resorption, is elevated in rheumatoid arthritis. Arthritis Rheum. 2006 May; 54(5):1451-62. PMID: 16649193.
    Citations: 32     Fields:    Translation:HumansAnimalsCells
  67. Adamopoulos IE, Danks L, Itonaga I, Locklin RM, Sabokbar A, Ferguson DJ, Athanasou NA. Stimulation of osteoclast formation by inflammatory synovial fluid. Virchows Arch. 2006 Jul; 449(1):69-77. PMID: 16642388.
    Citations: 7     Fields:    Translation:HumansCells
  68. Adamopoulos IE, Athanasou NA. Hepatocyte growth factor in normal and diseased bone and joint tissues. Curr Rheumatol Rev. 2006; 2(1):1-7. PMID: 25312908.
    Citations: 3     Fields:    
  69. Adamopoulos IE, Sabokbar A, Wordsworth BP, Carr A, Ferguson DJ, Athanasou NA. Synovial fluid macrophages are capable of osteoclast formation and resorption. J Pathol. 2006 Jan; 208(1):35-43. PMID: 16278818.
    Citations: 33     Fields:    Translation:HumansCells
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.