Harvard Catalyst Profiles

Peking University, Beijing, China	BS	06/2006	Biological Sciences
Harvard University, Cambridge, MA	PhD	06/2013	Biochemistry
Yale School of Medicine, New Haven, CT	Postdoc	12/2020	Immunobiology

Xu Zhou is a Principal Investigator in the Division of Gastroenterology, Hepatology and Nutrition, at the department of Pediatrics of Boston Childrens Hospital, and a member of faculty at Harvard Medical School. Dr. Zhou earned a B.S. from Peking University studying viral capsule protein of Hepatitis virus B. He obtained a Ph.D. with Dr. Erin OShea in the Department of Molecular and Cellular Biology at Harvard University, studying systems biology and transcriptional regulation. He then completed his postdoctoral training with Dr. Ruslan Medzhitov in the Department of Immunobiology at Yale University School of Medicine, investigating the mechanisms of tissue homeostasis and inflammation. The Zhou lab opened its door at Boston Childrens Hospital in 2021. The long-term goal of the Zhou lab is to decipher molecular and cellular mechanisms regulating tissue homeostasis and inflammation, and to understand how dysregulation of these processes leads to inflammatory disorders. To achieve this goal, they apply interdisciplinary approaches across immunology, systems biology, molecular and cellular biology, with a focus on the communication between immune and non-immune cell types and between cells and their microenvironment.

• Inflammation
• Tissue homeostasis
• Systems immunology
• Macrophage
• Stromal Cell
• Cell-cell communication
• microenvironment