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Niranjan Khadka, Ph.D.

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City University of New York, New YorkPhD06/2020Biomedical Engineering
City University of New York, New YorkMPhil06/2018Biomedical Engineering
City College of New York, New YorkBE05/2014Biomedical Engineering
2020 - 2021
Jake Zabara Young Investigator Award
2020 - 2020
Travel Award
2019 - 2020
Co- Investigator
2016 - 2017
Outstanding Researcher
2015 - 2015
Top 10 Finalist, Medical Device with commercial potential
2013 - 2014
Hersh Fellowship
2013 - 2014
Best Research and Academic Standing
2011 - 2011
New American Fellowship
2011 - 2011
MIT Honors in Circuits and Electronic Course

- Results-oriented biomedical engineer with 10+ years of hands-on experience in research and development of technologies utilized in brain/spinal cord electrical stimulation.
- Proven track record in computational FEM modeling of both MRI and CAD derived brain and spinal cord models, benchtop device fabrication and testing, signal and image processing, working with clinicians, manuscript publishing, grant writing, patent drafting, and knowledge of IRB and FDA documentation.

The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
  1. R01NS112996 (BIKSON, MAROM) May 1, 2020 - Apr 30, 2023
    kHz frequency Spinal Cord Stimulation: Novel Temperature-Based Mechanisms of Action
    Role: Co-Investigator

Featured Content

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Unal G, Swami JK, Canela C, Cohen SL, Khadka N, FallahRad M, Short B, Argyelan M, Sackeim HA, Bikson M. Adaptive current-flow models of ECT: Explaining individual static impedance, dynamic impedance, and brain current density. Brain Stimul. 2021 Jul 28; 14(5):1154-1168. PMID: 34332156.
    Citations:    Fields:    
  2. Truong DQ, Khadka N, Bikson, M. Transcranial Electrical Stimulation. 2021; 271-292. View Publication.
  3. Unal G, Swami J, Canela C, Cohen SL, Khadka N, Rad M, Short B, Argyelan M, Sackeim HA, Bikson M. Adaptive current-flow models of ECT: Explaining individual static impedance, dynamic impedance, and brain current density. 2021. View Publication.
  4. Khadka N, Woods AJ, Bikson M. Transcranial direct current stimulation electrodes. 2021; 263-291. View Publication.
  5. Khadka N, Seibt O, Patel V, Thomas C, Mokrejs A, Guleyupoglu B, Truong DQ, Bikson M. Factors Influencing Current Flow Through the Skin during Transcranial Electrical Stimulation: Role of Waveform, Tissue Properties, and Macro-Pores. 2021; 10(1):e16. View Publication.
  6. Khadka N, Bikson M. Neurocapillary-Modulation. Neuromodulation. 2020 Dec 19. PMID: 33340187.
    Citations: 1     Fields:    
  7. Khadka N, Bikson M. Role of skin tissue layers and ultra-structure in transcutaneous electrical stimulation including tDCS. Phys Med Biol. 2020 11 24; 65(22):225018. PMID: 32916670.
    Citations: 1     Fields:    Translation:Humans
  8. Khadka N. Influence of Transdermal Current Flow in TDCS-Induced Cutaneous Adverse Events. 2020. View Publication.
  9. Khadka N, Liu X, Zander H, Swami J, Rogers E, Lempka SF, Bikson M. Realistic anatomically detailed open-source spinal cord stimulation (RADO-SCS) model. J Neural Eng. 2020 04 23; 17(2):026033. PMID: 32209741.
    Citations: 1     Fields:    Translation:Humans
  10. Dressler K, Zannou AL, Khadka N, FallahRad M, Truong D, Bikson M. Advanced anatomically-realistic SCS heat Phantom for verifying Temperature Increases by kHz Spinal Cord Stimulation System. 2020; 23(3). View Publication.
  11. Khadka N, Harmsen IE, Lozano AM, Bikson M. Bio-Heat Model of Kilohertz-Frequency Deep Brain Stimulation Increases Brain Tissue Temperature. Neuromodulation. 2020 Jun; 23(4):489-495. PMID: 32058634.
    Citations: 4     Fields:    Translation:Humans
  12. Shin DW, Fan J, Luu E, Khalid W, Xia Y, Khadka N, Bikson M, Fu BM. In Vivo Modulation of the Blood-Brain Barrier Permeability by Transcranial Direct Current Stimulation (tDCS). Ann Biomed Eng. 2020 Apr; 48(4):1256-1270. PMID: 31916126.
    Citations: 5     Fields:    Translation:Animals
  13. Khadka N, Bikson M. Response to the Letter to the Editor by Caraway et al. on "Tissue Temperature Increases by a 10 kHz Spinal Cord Stimulation System: Phantom and Bioheat Model". Neuromodulation. 2019 12; 22(8):988. PMID: 31846544.
    Citations: 2     Fields:    Translation:Humans
  14. Khadka N, Truong DQ, Williams P, Martin JH, Bikson M. The Quasi-uniform assumption for Spinal Cord Stimulation translational research. J Neurosci Methods. 2019 12 01; 328:108446. PMID: 31589892.
    Citations: 3     Fields:    Translation:HumansAnimals
  15. Khadka N, Borges H, Paneri B, Kaufman T, Nassis E, Zannou AL, Shin Y, Choi H, Kim S, Lee K, Bikson M. Adaptive current tDCS up to 4?mA. Brain Stimul. 2020 Jan - Feb; 13(1):69-79. PMID: 31427272.
    Citations: 7     Fields:    Translation:Humans
  16. Zannou AL, Khadka N, FallahRad M, Truong DQ, Kopell BH, Bikson M. Tissue Temperature Increases by a 10 kHz Spinal Cord Stimulation System: Phantom and Bioheat Model. Neuromodulation. 2019 Jun 21. PMID: 31225695.
    Citations: 7     Fields:    
  17. FallahRad M, Zannou AL, Khadka N, Prescott SA, Ratté S, Zhang T, Esteller R, Hershey B, Bikson M. Electrophysiology equipment for reliable study of kHz electrical stimulation. J Physiol. 2019 04; 597(8):2131-2137. PMID: 30816558.
    Citations: 3     Fields:    
  18. Khadka N, Zannou A, Truong D, Zhang T, Esteller R, Hersey B, Bikson M. Generation 2 kilohertz spinal cord stimulation (kHz-SCS) bioheat multi-physics model. 2019; 12(2):566. View Publication.
  19. Tarbell J, Bikson M, Cancel LM, Khadka N. Direct current stimulation of endothelial monolayers induces an increase in transport by the electroosmotic effect. 2019; 12(2):e12. View Publication.
  20. Hadar R, Winter R, Edemann-Callesen H, Wieske F, Habelt B, Khadka N, Felgel-Farnholz V, Barroeta-Hlusicka E, Reis J, Tatarau CA, Funke K, Fritsch B, Bernhardt N, Bikson M, Nitsche MA, Winter C. Prevention of schizophrenia deficits via non-invasive adolescent frontal cortex stimulation in rats. Mol Psychiatry. 2020 04; 25(4):896-905. PMID: 30692610.
    Citations: 7     Fields:    Translation:Animals
  21. Seibt O, Truong D, Khadka N, Huang Y, Bikson M. Computational Finite Element Method (FEM) forward modeling workflow for transcranial Direct Current Stimulation (tDCS) current flow on MRI-derived head: Simpleware and COMSOL Multiphysics tutorial. 2019. View Publication.
  22. Bikson M, Datta A, Khadka N. Electrode Assemblies for Delivering Therapeutic Electrostimulation. 2018. View Publication.
  23. Zannou AL, Khadka N, Truong DQ, Zhang T, Esteller R, Hershey B, Bikson M. Temperature increases by kilohertz frequency spinal cord stimulation. Brain Stimul. 2019 Jan - Feb; 12(1):62-72. PMID: 30482674.
    Citations: 9     Fields:    Translation:Humans
  24. Khadka N, Borges H, Zannou AL, Jang J, Kim B, Lee K, Bikson M. Dry tDCS: Tolerability of a novel multilayer hydrogel composite non-adhesive electrode for transcranial direct current stimulation. Brain Stimul. 2018 Sep - Oct; 11(5):1044-1053. PMID: 30072144.
    Citations: 2     Fields:    Translation:Humans
  25. Fu BM, Shin DW, Fan J, Khadka N, Luu E, Khalid W, Xia Y, Bikson M. Inhibition of Nitric Oxide Synthase (NOS) by NG-monomethyl-L-arginine (L-NMMA) Reduces Transient Increase in the Blood-Brain Barrier Solute Permeability. 2018; 32:922.2-922.2. View Publication.
  26. Edemann-Callesen H, Habelt B, Wieske F, Jackson M, Khadka N, Mattei D, Bernhardt N, Heinz A, Liebetanz D, Bikson M, Padberg F, Hadar R, Nitsche MA, Winter C. Non-invasive modulation reduces repetitive behavior in a rat model through the sensorimotor cortico-striatal circuit. Transl Psychiatry. 2018 01 10; 8(1):11. PMID: 29317605.
    Citations: 4     Fields:    Translation:Animals
  27. Leite J, Gonçalves ÓF, Pereira P, Khadka N, Bikson M, Fregni F, Carvalho S. The differential effects of unihemispheric and bihemispheric tDCS over the inferior frontal gyrus on proactive control. Neurosci Res. 2018 May; 130:39-46. PMID: 28842243.
    Citations: 4     Fields:    Translation:Humans
  28. Esmaeilpour Z, Milosevic M, Azevedo K, Khadka N, Navarro J, Brunoni A, Popovic MR, Bikson M, Fonoff ET. Intracranial voltage recording during transcranial direct current stimulation (tDCS) in human subjects with validation of a standard model. 2017; 10(4):E72-E75. View Publication.
  29. Chen CF, Bikson M, Chou LW, Shan C, Khadka N, Chen WS, Fregni F. Higher-order power harmonics of pulsed electrical stimulation modulates corticospinal contribution of peripheral nerve stimulation. Sci Rep. 2017 03 03; 7:43619. PMID: 28256638.
    Citations: 2     Fields:    Translation:Animals
  30. Khadka N, Zannou AL, Zunara F, Truong DQ, Dmochowski J, Bikson M. Minimal Heating at the Skin Surface During Transcranial Direct Current Stimulation. Neuromodulation. 2018 Jun; 21(4):334-339. PMID: 28111832.
    Citations: 4     Fields:    Translation:Humans
  31. Ezquerro F, Moffa AH, Bikson M, Khadka N, Aparicio LV, de Sampaio-Junior B, Fregni F, Bensenor IM, Lotufo PA, Pereira AC, Brunoni AR. The Influence of Skin Redness on Blinding in Transcranial Direct Current Stimulation Studies: A Crossover Trial. Neuromodulation. 2017 Apr; 20(3):248-255. PMID: 27704654.
    Citations: 7     Fields:    Translation:Humans
  32. Alam M, Truong DQ, Khadka N, Bikson M. Spatial and polarity precision of concentric high-definition transcranial direct current stimulation (HD-tDCS). Phys Med Biol. 2016 06 21; 61(12):4506-21. PMID: 27223853.
    Citations: 36     Fields:    Translation:Humans
  33. Paneri B, Adair D, Thomas C, Khadka N, Patel V, Tyler WJ, Parra L, Bikson M. Tolerability of Repeated Application of Transcranial Electrical Stimulation with Limited Outputs to Healthy Subjects. Brain Stimul. 2016 Sep-Oct; 9(5):740-754. PMID: 27372844.
    Citations: 13     Fields:    Translation:Humans
  34. Bikson M, Parra L, Datta A, Khadka N, Macuff SA. System and method for conducting multi-electrode electrical stimulation. 2016. View Publication.
  35. Shin DW, Khadka N, Fan J, Bikson M, Fu BM. Transcranial direct current stimulation transiently increases the blood-brain barrier solute permeability in vivo. 2016; 9788. View Publication.
  36. Bikson M, Truong DQ, Mourdoukoutas AP, Aboseria M, Khadka N, Adair D, Rahman A. Modeling sequence and quasi-uniform assumption in computational neurostimulation. Prog Brain Res. 2015; 222:1-23. PMID: 26541374.
    Citations: 18     Fields:    Translation:HumansAnimals
  37. Sarantos C, Bekritsky J, Khadka N, Bikson M, Adusumilli P. Design of Wireless Intra-Operative Pulse Oximeter With Reticulated Pressure-Sensitive Head. 2015; 9(3). View Publication.
  38. Paneri B, Khadka N, Patel V, Thomas C, Tyler W, Parra L, Bikson M. The tolerability of transcranial electrical stimulation used across extended periods in a naturalistic context by healthy individuals. 2015. View Publication.
  39. Khadka N, Truong DQ, Bikson M. Principles of within electrode current steering. 2015; 9(2). View Publication.
  40. Khadka N, Rahman A, Sarantos C, Truong DQ, Bikson M. Methods for specific electrode resistance measurement during transcranial direct current stimulation. Brain Stimul. 2015 Jan-Feb; 8(1):150-9. PMID: 25456981.
    Citations: 3     Fields:    Translation:Humans
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.