Harvard Catalyst Profiles

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Randall Mazzarino, Ph.D.


Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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  1. Sandberg AA, Manning E, Wilkins HM, Mazzarino R, Minckley T, Swerdlow RH, Patterson D, Qin Y, Linseman DA. Mitochondrial Targeting of Amyloid-ß Protein Precursor Intracellular Domain Induces Hippocampal Cell Death via a Mechanism Distinct from Amyloid-ß. J Alzheimers Dis. 2022; 86(4):1727-1744. PMID: 35253745.
    Citations: 1     Fields:    Translation:HumansCells
  2. Mazzarino RC, Baresova V, Zikánová M, Duval N, Wilkinson TG, Patterson D, Vacano GN. Transcriptome and metabolome analysis of crGART, a novel cell model of de novo purine synthesis deficiency: Alterations in CD36 expression and activity. PLoS One. 2021; 16(7):e0247227. PMID: 34283828.
    Citations:    Fields:    Translation:HumansCells
  3. Mazzarino RC. Targeting Future Pandemics, a Case for De Novo Purine Synthesis and Basic Research. Front Immunol. 2021; 12:694300. PMID: 34177959.
    Citations: 1     Fields:    Translation:HumansAnimalsCellsPHPublic Health
  4. Stepanova V, Moczulska KE, Vacano GN, Kurochkin I, Ju X, Riesenberg S, Macak D, Maricic T, Dombrowski L, Schörnig M, Anastassiadis K, Baker O, Naumann R, Khrameeva E, Vanushkina A, Stekolshchikova E, Egorova A, Tkachev A, Mazzarino R, Duval N, Zubkov D, Giavalisco P, Wilkinson TG, Patterson D, Khaitovich P, Pääbo S. Reduced purine biosynthesis in humans after their divergence from Neandertals. Elife. 2021 05 04; 10. PMID: 33942714.
    Citations:    Fields:    Translation:HumansAnimalsCells
  5. Mazzarino RC, Baresova V, Zikánová M, Duval N, Wilkinson TG, Patterson D, Vacano GN. The CRISPR-Cas9 crATIC HeLa transcriptome: Characterization of a novel cellular model of ATIC deficiency and ZMP accumulation. Mol Genet Metab Rep. 2020 Dec; 25:100642. PMID: 32939338; PMCID: PMC7479443.
    Citations: 4     
  6. Koza LA, Winter AN, Holsopple J, Baybayon-Grandgeorge AN, Pena C, Olson JR, Mazzarino RC, Patterson D, Linseman DA. Protocatechuic Acid Extends Survival, Improves Motor Function, Diminishes Gliosis, and Sustains Neuromuscular Junctions in the hSOD1G93A Mouse Model of Amyotrophic Lateral Sclerosis. Nutrients. 2020 Jun 18; 12(6). PMID: 32570926.
    Citations: 4     Fields:    Translation:AnimalsCells
  7. Mazzarino RC, Baresova V, Zikánová M, Duval N, Wilkinson TG, Patterson D, Vacano GN. The CRISPR-Cas9 crADSL HeLa transcriptome: A first step in establishing a model for ADSL deficiency and SAICAR accumulation. Mol Genet Metab Rep. 2019 Dec; 21:100512. PMID: 31516833; PMCID: PMC6731210.
    Citations: 7     
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.