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Raphael Knaier, Ph.D.

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University of Basel, Basel, SwitzerlandPhD10/2017Exercise Physiology
University of Leipzig, Leipzig, GermanyM.Sc.03/2013Sport Science
University of Bremen, Bremen, GermanyB.A.09/2009Sport Science
Dissertation award, Faculty of Medicine, University of Basel, Switzerland

Raphael Knaier is a Research Fellow at Harvard Medical School in the Division of Sleep and Circadian Disorders at Brigham and Women's Hospital in Boston, MA.
Dr. Knaier is an exercise physiologist who completed his M.Sc. at the University of Leipzig, Germany. He earned his PhD at the University of Basel, Switzerland under the supervision of Prof. Arno Schmidt-Trucksaess and Prof. Christian Cajochen. In his PhD project he investigated the impact of bright light and monochromatic blue light exposures on cycling performance in athletes and obese individuals. He continued his work at the University of Basel for the first phase of his postdoctoral training. During this period he mainly investigated the physical functional capacity in healthy individuals and cardiac patients.
For the second phase of his postdoctoral training Dr. Knaier joined the Medical Chronobiology Program under the supervision of Dr. Frank A.J.L. Scheer to investigate the impact of pre-surgical physical fitness on the weight loss after bariatric surgery and to receive training on how to perform highly controlled in-lab studies in humans.
Dr. Knaier's research interests also lie in understanding how human behavior such as sleep, nutrition, and especially physical activity affect the circadian rhythm and how the timing of exercise affects human health.

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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  1. Streese L, Lona G, Wagner J, Knaier R, Burri A, Nève G, Infanger D, Vilser W, Schmidt-Trucksäss A, Hanssen H. Normative data and standard operating procedures for static and dynamic retinal vessel analysis as biomarker for cardiovascular risk. Sci Rep. 2021 Jul 08; 11(1):14136. PMID: 34238996.
    Citations:    Fields:    
  2. Königstein K, Wagner J, Frei M, Knaier R, Klenk C, Carrard J, Schwarz A, Hinrichs T, Schmidt-Trucksäss A. Endothelial function of healthy adults from 20 to 91 years of age: prediction of cardiovascular risk by vasoactive range. J Hypertens. 2021 Jul 01; 39(7):1361-1369. PMID: 33470736.
    Citations:    Fields:    
  3. Carrard J, Gallart-Ayala H, Infanger D, Teav T, Wagner J, Knaier R, Colledge F, Streese L, Königstein K, Hinrichs T, Hanssen H, Ivanisevic J, Schmidt-Trucksäss A. Metabolic View on Human Healthspan: A Lipidome-Wide Association Study. Metabolites. 2021 Apr 30; 11(5). PMID: 33946321.
  4. Niemeyer M, Knaier R, Beneke R. The Oxygen Uptake Plateau-A Critical Review of the Frequently Misunderstood Phenomenon. Sports Med. 2021 Apr 29. PMID: 33914281.
    Citations:    Fields:    
  5. Wagner J, Niemeyer M, Infanger D, Hinrichs T, Guerra C, Klenk C, Königstein K, Cajochen C, Schmidt-Trucksäss A, Knaier R. Verification-phase tests show low reliability and add little value in determining [Formula: see text]O2max in young trained adults. PLoS One. 2021; 16(1):e0245306. PMID: 33428687.
    Citations: 1     Fields:    Translation:HumansCTClinical Trials
  6. Wagner J, Knaier R, Infanger D, Königstein K, Klenk C, Carrard J, Hanssen H, Hinrichs T, Seals D, Schmidt-Trucksäss A. Novel CPET Reference Values in Healthy Adults: Associations with Physical Activity. Med Sci Sports Exerc. 2021 01; 53(1):26-37. PMID: 32826632.
    Citations: 1     Fields:    Translation:Humans
  7. Wagner J, Knaier R, Königstein K, Klenk C, Carrard J, Lichtenstein E, Scharnagl H, März W, Hanssen H, Hinrichs T, Schmidt-Trucksäss A, Arbeev K. Composite Measures of Physical Fitness to Discriminate Between Healthy Aging and Heart Failure: The COmPLETE Study. Front Physiol. 2020; 11:596240. PMID: 33384610.
  8. Wagner J, Niemeyer M, Infanger D, Hinrichs T, Streese L, Hanssen H, Myers J, Schmidt-Trucksäss A, Knaier R. New Data-based Cutoffs for Maximal Exercise Criteria across the Lifespan. Med Sci Sports Exerc. 2020 09; 52(9):1915-1923. PMID: 32224715.
    Citations: 4     Fields:    Translation:Humans
  9. Höchsmann C, Knaier R, Infanger D, Schmidt-Trucksäss A. Validity of smartphones and activity trackers to measure steps in a free-living setting over three consecutive days. Physiol Meas. 2020 01 30; 41(1):015001. PMID: 31851949.
    Citations: 3     Fields:    Translation:Humans
  10. Knaier R, Infanger D, Cajochen C, Schmidt-Trucksaess A, Faude O, Roth R. Diurnal and day-to-day variations in isometric and isokinetic strength. Chronobiol Int. 2019 11; 36(11):1537-1549. PMID: 31476879.
    Citations: 1     Fields:    Translation:Humans
  11. Wagner J, Knaier R, Infanger D, Arbeev K, Briel M, Dieterle T, Hanssen H, Faude O, Roth R, Hinrichs T, Schmidt-Trucksäss A. Functional aging in health and heart failure: the COmPLETE Study. BMC Cardiovasc Disord. 2019 07 30; 19(1):180. PMID: 31362698.
    Citations: 4     Fields:    Translation:Humans
  12. Knaier R, Niemeyer M, Wagner J, Infanger D, Hinrichs T, Klenk C, Frutig S, Cajochen C, Schmidt-TRUCKSäSS A. Which Cutoffs for Secondary V?O2max Criteria Are Robust to Diurnal Variations? Med Sci Sports Exerc. 2019 05; 51(5):1006-1013. PMID: 30550515.
    Citations: 7     Fields:    Translation:Humans
  13. Knaier R, Infanger D, Niemeyer M, Cajochen C, Schmidt-Trucksäss A. In Athletes, the Diurnal Variations in Maximum Oxygen Uptake Are More Than Twice as Large as the Day-to-Day Variations. Front Physiol. 2019; 10:219. PMID: 30936835.
    Citations: 5     
  14. Knaier R, Höchsmann C, Infanger D, Hinrichs T, Schmidt-Trucksäss A. Validation of automatic wear-time detection algorithms in a free-living setting of wrist-worn and hip-worn ActiGraph GT3X. BMC Public Health. 2019 Feb 28; 19(1):244. PMID: 30819148.
    Citations: 11     Fields:    Translation:Humans
  15. Höchsmann C, Knaier R, Eymann J, Hintermann J, Infanger D, Schmidt-Trucksäss A. Validity of activity trackers, smartphones, and phone applications to measure steps in various walking conditions. Scand J Med Sci Sports. 2018 Jul; 28(7):1818-1827. PMID: 29460319.
    Citations: 24     Fields:    Translation:Humans
  16. Knaier R, Klenk C, Königstein K, Hinrichs T, Rossmeissl A, Infanger D, Cajochen C, Schmidt-Trucksäss A. Morning bright light exposure has no influence on self-chosen exercise intensity and mood in overweight individuals - A randomized controlled trial. Chronobiol Int. 2018 04; 35(4):477-485. PMID: 29260907.
    Citations: 1     Fields:    Translation:Humans
  17. Knaier R, Schäfer J, Rossmeissl A, Klenk C, Hanssen H, Höchsmann C, Cajochen C, Schmidt-Trucksäss A. Effects of bright and blue light on acoustic reaction time and maximum handgrip strength in male athletes: a randomized controlled trial. Eur J Appl Physiol. 2017 Aug; 117(8):1689-1696. PMID: 28597081.
    Citations: 1     Fields:    Translation:Humans
  18. Knaier R, Schäfer J, Rossmeissl A, Klenk C, Hanssen H, Höchsmann C, Cajochen C, Schmidt-Trucksäss A. Prime Time Light Exposures Do Not Seem to Improve Maximal Physical Performance in Male Elite Athletes, but Enhance End-Spurt Performance. Front Physiol. 2017; 8:264. PMID: 28507521.
    Citations: 3     
  19. Knaier R, Meister S, Aeschbacher T, Gemperle D, Rossmeissl A, Cajochen C, Schmidt-Trucksäss A. Dose-response relationship between light exposure and cycling performance. Scand J Med Sci Sports. 2016 Jul; 26(7):794-801. PMID: 26271769.
    Citations: 4     Fields:    Translation:Humans
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.