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Anna Feeney

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Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Barajas-Mora EM, Feeney AJ. Enhancers as regulators of antigen receptor loci three-dimensional chromatin structure. Transcription. 2020 Feb; 11(1):37-51. PMID: 31829768.
    Citations: 1     Fields:    
  2. Arends T, Dege C, Bortnick A, Danhorn T, Knapp JR, Jia H, Harmacek L, Fleenor CJ, Straign D, Walton K, Leach SM, Feeney AJ, Murre C, O'Connor BP, Hagman JR. CHD4 is essential for transcriptional repression and lineage progression in B lymphopoiesis. Proc Natl Acad Sci U S A. 2019 05 28; 116(22):10927-10936. PMID: 31085655.
    Citations: 3     Fields:    Translation:AnimalsCells
  3. Kenter AL, Feeney AJ. New insights emerge as antibody repertoire diversification meets chromosome conformation. F1000Res. 2019; 8. PMID: 30984378.
    Citations: 4     Fields:    Translation:Cells
  4. Voss JE, Gonzalez-Martin A, Andrabi R, Fuller RP, Murrell B, McCoy LE, Porter K, Huang D, Li W, Sok D, Le K, Briney B, Chateau M, Rogers G, Hangartner L, Feeney AJ, Nemazee D, Cannon P, Burton DR. Reprogramming the antigen specificity of B cells using genome-editing technologies. Elife. 2019 01 17; 8. PMID: 30648968.
    Citations: 8     Fields:    Translation:HumansCells
  5. Barajas-Mora EM, Kleiman E, Xu J, Carrico NC, Lu H, Oltz EM, Murre C, Feeney AJ. A B-Cell-Specific Enhancer Orchestrates Nuclear Architecture to Generate a Diverse Antigen Receptor Repertoire. Mol Cell. 2019 01 03; 73(1):48-60.e5. PMID: 30449725.
    Citations: 7     Fields:    Translation:HumansAnimalsCells
  6. Kleiman E, Loguercio S, Feeney AJ. Epigenetic Enhancer Marks and Transcription Factor Binding Influence V? Gene Rearrangement in Pre-B Cells and Pro-B Cells. Front Immunol. 2018; 9:2074. PMID: 30271408.
    Citations: 3     Fields:    Translation:AnimalsCells
  7. Kleiman E, Xu J, Feeney AJ. Cutting Edge: Proper Orientation of CTCF Sites in Cer Is Required for Normal J?-Distal and J?-Proximal V? Gene Usage. J Immunol. 2018 09 15; 201(6):1633-1638. PMID: 30076197.
    Citations: 6     Fields:    Translation:AnimalsCells
  8. Loguercio S, Barajas-Mora EM, Shih HY, Krangel MS, Feeney AJ. Variable Extent of Lineage-Specificity and Developmental Stage-Specificity of Cohesin and CCCTC-Binding Factor Binding Within the Immunoglobulin and T Cell Receptor Loci. Front Immunol. 2018; 9:425. PMID: 29593713.
    Citations: 11     Fields:    Translation:AnimalsCells
  9. Kleiman E, Jia H, Loguercio S, Su AI, Feeney AJ. YY1 plays an essential role at all stages of B-cell differentiation. Proc Natl Acad Sci U S A. 2016 07 05; 113(27):E3911-20. PMID: 27335461.
    Citations: 17     Fields:    Translation:AnimalsCells
  10. Gerasimova T, Guo C, Ghosh A, Qiu X, Montefiori L, Verma-Gaur J, Choi NM, Feeney AJ, Sen R. A structural hierarchy mediated by multiple nuclear factors establishes IgH locus conformation. Genes Dev. 2015 Aug 15; 29(16):1683-95. PMID: 26302788.
    Citations: 18     Fields:    Translation:AnimalsCells
  11. Choi NM, Feeney AJ. CTCF and ncRNA Regulate the Three-Dimensional Structure of Antigen Receptor Loci to Facilitate V(D)J Recombination. Front Immunol. 2014; 5:49. PMID: 24575097.
    Citations: 11     Fields:    
  12. Predeus AV, Gopalakrishnan S, Huang Y, Tang J, Feeney AJ, Oltz EM, Artyomov MN. Targeted chromatin profiling reveals novel enhancers in Ig H and Ig L chain Loci. J Immunol. 2014 Feb 01; 192(3):1064-70. PMID: 24353267.
    Citations: 9     Fields:    Translation:AnimalsCells
  13. Kumar S, Wuerffel R, Achour I, Lajoie B, Sen R, Dekker J, Feeney AJ, Kenter AL. Flexible ordering of antibody class switch and V(D)J joining during B-cell ontogeny. Genes Dev. 2013 Nov 15; 27(22):2439-44. PMID: 24240234.
    Citations: 20     Fields:    Translation:AnimalsCells
  14. Gopalakrishnan S, Majumder K, Predeus A, Huang Y, Koues OI, Verma-Gaur J, Loguercio S, Su AI, Feeney AJ, Artyomov MN, Oltz EM. Unifying model for molecular determinants of the preselection Vß repertoire. Proc Natl Acad Sci U S A. 2013 Aug 20; 110(34):E3206-15. PMID: 23918392.
    Citations: 24     Fields:    Translation:AnimalsCells
  15. Choi NM, Loguercio S, Verma-Gaur J, Degner SC, Torkamani A, Su AI, Oltz EM, Artyomov M, Feeney AJ. Deep sequencing of the murine IgH repertoire reveals complex regulation of nonrandom V gene rearrangement frequencies. J Immunol. 2013 Sep 01; 191(5):2393-402. PMID: 23898036.
    Citations: 41     Fields:    Translation:AnimalsCells
  16. Shih HY, Verma-Gaur J, Torkamani A, Feeney AJ, Galjart N, Krangel MS. Tcra gene recombination is supported by a Tcra enhancer- and CTCF-dependent chromatin hub. Proc Natl Acad Sci U S A. 2012 Dec 11; 109(50):E3493-502. PMID: 23169622.
    Citations: 29     Fields:    Translation:AnimalsCells
  17. Verma-Gaur J, Torkamani A, Schaffer L, Head SR, Schork NJ, Feeney AJ. Noncoding transcription within the Igh distal V(H) region at PAIR elements affects the 3D structure of the Igh locus in pro-B cells. Proc Natl Acad Sci U S A. 2012 Oct 16; 109(42):17004-9. PMID: 23027941.
    Citations: 42     Fields:    Translation:Cells
  18. Corcoran AE, Feeney AJ. Editorial overview. Lymphocyte development. Curr Opin Immunol. 2012 Apr; 24(2):129-31. PMID: 22440337.
    Citations:    Fields:    Translation:HumansAnimalsCells
  19. Volpi SA, Verma-Gaur J, Hassan R, Ju Z, Roa S, Chatterjee S, Werling U, Hou H, Will B, Steidl U, Scharff M, Edelman W, Feeney AJ, Birshtein BK. Germline deletion of Igh 3' regulatory region elements hs 5, 6, 7 (hs5-7) affects B cell-specific regulation, rearrangement, and insulation of the Igh locus. J Immunol. 2012 Mar 15; 188(6):2556-66. PMID: 22345664.
    Citations: 22     Fields:    Translation:AnimalsCells
  20. Feeney AJ, Verma-Gaur J. CTCF-cohesin complex: architect of chromatin structure regulates V(D)J rearrangement. Cell Res. 2012 Feb; 22(2):280-2. PMID: 22105486.
    Citations: 6     Fields:    Translation:AnimalsCells
  21. Degner SC, Verma-Gaur J, Wong TP, Bossen C, Iverson GM, Torkamani A, Vettermann C, Lin YC, Ju Z, Schulz D, Murre CS, Birshtein BK, Schork NJ, Schlissel MS, Riblet R, Murre C, Feeney AJ. CCCTC-binding factor (CTCF) and cohesin influence the genomic architecture of the Igh locus and antisense transcription in pro-B cells. Proc Natl Acad Sci U S A. 2011 Jun 07; 108(23):9566-71. PMID: 21606361.
    Citations: 103     Fields:    Translation:AnimalsCells
  22. Feeney AJ. Epigenetic regulation of antigen receptor gene rearrangement. Curr Opin Immunol. 2011 Apr; 23(2):171-7. PMID: 21216580.
    Citations: 8     Fields:    Translation:HumansCells
  23. Degner-Leisso SC, Feeney AJ. Epigenetic and 3-dimensional regulation of V(D)J rearrangement of immunoglobulin genes. Semin Immunol. 2010 Dec; 22(6):346-52. PMID: 20833065.
    Citations: 24     Fields:    Translation:HumansAnimalsCells
  24. Lukin K, Fields S, Lopez D, Cherrier M, Ternyak K, Ramírez J, Feeney AJ, Hagman J. Compound haploinsufficiencies of Ebf1 and Runx1 genes impede B cell lineage progression. Proc Natl Acad Sci U S A. 2010 Apr 27; 107(17):7869-74. PMID: 20385820.
    Citations: 28     Fields:    Translation:AnimalsCells
  25. Xu CR, Feeney AJ. The epigenetic profile of Ig genes is dynamically regulated during B cell differentiation and is modulated by pre-B cell receptor signaling. J Immunol. 2009 Feb 01; 182(3):1362-9. PMID: 19155482.
    Citations: 22     Fields:    Translation:AnimalsCells
  26. Feeney AJ. Genetic and epigenetic control of V gene rearrangement frequency. Adv Exp Med Biol. 2009; 650:73-81. PMID: 19731802.
    Citations: 10     Fields:    Translation:HumansAnimalsCells
  27. Degner SC, Wong TP, Jankevicius G, Feeney AJ. Cutting edge: developmental stage-specific recruitment of cohesin to CTCF sites throughout immunoglobulin loci during B lymphocyte development. J Immunol. 2009 Jan 01; 182(1):44-8. PMID: 19109133.
    Citations: 84     Fields:    Translation:AnimalsCells
  28. Carey JB, Moffatt-Blue CS, Watson LC, Gavin AL, Feeney AJ. Repertoire-based selection into the marginal zone compartment during B cell development. J Exp Med. 2008 Sep 01; 205(9):2043-52. PMID: 18710933.
    Citations: 50     Fields:    Translation:AnimalsCells
  29. Xu CR, Schaffer L, Head SR, Feeney AJ. Reciprocal patterns of methylation of H3K36 and H3K27 on proximal vs. distal IgVH genes are modulated by IL-7 and Pax5. Proc Natl Acad Sci U S A. 2008 Jun 24; 105(25):8685-90. PMID: 18562282.
    Citations: 20     Fields:    Translation:AnimalsCells
  30. Lamoureux JL, Watson LC, Cherrier M, Skog P, Nemazee D, Feeney AJ. Reduced receptor editing in lupus-prone MRL/lpr mice. J Exp Med. 2007 Nov 26; 204(12):2853-64. PMID: 17967905.
    Citations: 17     Fields:    Translation:AnimalsCells
  31. Espinoza CR, Feeney AJ. Chromatin accessibility and epigenetic modifications differ between frequently and infrequently rearranging VH genes. Mol Immunol. 2007 Apr; 44(10):2675-85. PMID: 17218014.
    Citations: 6     Fields:    Translation:AnimalsCells
  32. Espinoza CR, Feeney AJ. Quantifying chromatin accessibility of individual gene family members by combining ligation-mediated PCR with real-time PCR. Biotechniques. 2006 Oct; 41(4):404, 406, 408. PMID: 17068954.
    Citations: 3     Fields:    Translation:AnimalsCells
  33. Watson LC, Moffatt-Blue CS, McDonald RZ, Kompfner E, Ait-Azzouzene D, Nemazee D, Theofilopoulos AN, Kono DH, Feeney AJ. Paucity of V-D-D-J rearrangements and VH replacement events in lupus prone and nonautoimmune TdT-/- and TdT+/+ mice. J Immunol. 2006 Jul 15; 177(2):1120-8. PMID: 16818769.
    Citations: 14     Fields:    Translation:AnimalsCells
  34. Zhang Z, Espinoza CR, Yu Z, Stephan R, He T, Williams GS, Burrows PD, Hagman J, Feeney AJ, Cooper MD. Transcription factor Pax5 (BSAP) transactivates the RAG-mediated V(H)-to-DJ(H) rearrangement of immunoglobulin genes. Nat Immunol. 2006 Jun; 7(6):616-24. PMID: 16680144.
    Citations: 24     Fields:    Translation:HumansAnimalsCells
  35. Espinoza CR, Feeney AJ. The extent of histone acetylation correlates with the differential rearrangement frequency of individual VH genes in pro-B cells. J Immunol. 2005 Nov 15; 175(10):6668-75. PMID: 16272322.
    Citations: 13     Fields:    Translation:AnimalsCells
  36. Li L, Salido E, Zhou Y, Bhattacharyya S, Yannone SM, Dunn E, Meneses J, Feeney AJ, Cowan MJ. Targeted disruption of the Artemis murine counterpart results in SCID and defective V(D)J recombination that is partially corrected with bone marrow transplantation. J Immunol. 2005 Feb 15; 174(4):2420-8. PMID: 15699179.
    Citations: 16     Fields:    Translation:HumansAnimalsCells
  37. Feeney AJ, Goebel P, Espinoza CR. Many levels of control of V gene rearrangement frequency. Immunol Rev. 2004 Aug; 200:44-56. PMID: 15242395.
    Citations: 12     Fields:    Translation:HumansCells
  38. Robey IF, Peterson M, Horwitz MS, Kono DH, Stratmann T, Theofilopoulos AN, Sarvetnick N, Teyton L, Feeney AJ. Terminal deoxynucleotidyltransferase deficiency decreases autoimmune disease in diabetes-prone nonobese diabetic mice and lupus-prone MRL-Fas(lpr) mice. J Immunol. 2004 Apr 01; 172(7):4624-9. PMID: 15034081.
    Citations: 11     Fields:    Translation:AnimalsCells
  39. Montalbano A, Ogwaro KM, Tang A, Matthews AG, Larijani M, Oettinger MA, Feeney AJ. V(D)J recombination frequencies can be profoundly affected by changes in the spacer sequence. J Immunol. 2003 Nov 15; 171(10):5296-304. PMID: 14607931.
    Citations: 8     Fields:    Translation:HumansCells
  40. Goebel P, Montalbano A, Ayers N, Kompfner E, Dickinson L, Webb CF, Feeney AJ. High frequency of matrix attachment regions and cut-like protein x/CCAAT-displacement protein and B cell regulator of IgH transcription binding sites flanking Ig V region genes. J Immunol. 2002 Sep 01; 169(5):2477-87. PMID: 12193717.
    Citations: 15     Fields:    Translation:HumansAnimalsCells
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.