Harvard Catalyst Profiles

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Tadashi Imafuku, Ph.D.

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Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Tanaka S, Watanabe H, Nakano T, Imafuku T, Kato H, Tokumaru K, Arimura N, Enoki Y, Maeda H, Tanaka M, Matsushita K, Fukagawa M, Maruyama T. Indoxyl Sulfate Contributes to Adipose Tissue Inflammation through the Activation of NADPH Oxidase. Toxins (Basel). 2020 08 05; 12(8). PMID: 32764271.
    Citations:    Fields:    Translation:AnimalsCells
  2. Watanabe H, Bi J, Murata R, Fujimura R, Nishida K, Imafuku T, Nakamura Y, Maeda H, Mukunoki A, Takeo T, Nakagata N, Kurauchi Y, Katsuki H, Tanaka M, Matsushita K, Fukagawa M, Maruyama T. A synthetic retinoic acid receptor agonist Am80 ameliorates renal fibrosis via inducing the production of alpha-1-acid glycoprotein. Sci Rep. 2020 07 10; 10(1):11424. PMID: 32651445.
    Citations:    Fields:    Translation:HumansAnimalsCells
  3. Tanaka R, Imafuku T, Suzuki Y, Nishida K, Matsusaka K, Shin T, Sato Y, Ishima Y, Watanabe H, Mimata H, Maruyama T, Itoh H. Changes in redox state of albumin before and after kidney transplantation in patients with end-stage renal disease. Clin Biochem. 2020 Jul; 81:20-26. PMID: 32380091.
    Citations:    Fields:    Translation:HumansCells
  4. Oniki K, Nohara H, Nakashima R, Obata Y, Muto N, Sakamoto Y, Ueno-Shuto K, Imafuku T, Ishima Y, Watanabe H, Maruyama T, Otake K, Ogata Y, Suico MA, Kai H, Shuto T, Saruwatari J. The DsbA-L gene is associated with respiratory function of the elderly via its adiponectin multimeric or antioxidant properties. Sci Rep. 2020 04 06; 10(1):5973. PMID: 32249844.
    Citations:    Fields:    Translation:HumansCells
  5. Oniki K, Kawakami T, Nakashima A, Miyata K, Watanabe T, Fujikawa H, Nakashima R, Nasu A, Eto Y, Takahashi N, Nohara H, Suico MA, Kotani S, Obata Y, Sakamoto Y, Seguchi Y, Saruwatari J, Imafuku T, Watanabe H, Maruyama T, Kai H, Shuto T. Melinjo seed extract increases adiponectin multimerization in physiological and pathological conditions. Sci Rep. 2020 03 09; 10(1):4313. PMID: 32152335.
    Citations:    Fields:    Translation:HumansAnimalsCellsCTClinical Trials
  6. Imafuku T, Tanaka M, Tokunaga K, Miyamura S, Kato H, Tanaka S, Nakano T, Hirata K, Kadowaki D, Maeda H, Matsushita K, Otagiri M, Komaba H, Fukagawa M, Watanabe H, Maruyama T. Effect of Cinacalcet on the Redox Status of Albumin in Secondary Hyperparathyroidism Patients Receiving Hemodialysis. Biol Pharm Bull. 2020; 43(10):1583-1590. PMID: 32999168.
    Citations:    Fields:    
  7. Hirata K, Watanabe H, Toyoda M, Sugimoto R, Ikegami K, Imafuku T, Matsuzaka K, Ichimizu S, Maeda H, Uekihara S, Jingami S, Maruyama T. Effect of Serum Parathyroid Hormone on Tacrolimus Therapy in Kidney Transplant Patients: A Possible Biomarker for a Tacrolimus Dosage Schedule. Biol Pharm Bull. 2019; 42(5):786-791. PMID: 31061321.
    Citations:    Fields:    Translation:Humans
  8. Bi J, Watanabe H, Fujimura R, Nishida K, Nakamura R, Oshiro S, Imafuku T, Komori H, Miyahisa M, Tanaka M, Matsushita K, Maruyama T. A downstream molecule of 1,25-dihydroxyvitamin D3, alpha-1-acid glycoprotein, protects against mouse model of renal fibrosis. Sci Rep. 2018 11 26; 8(1):17329. PMID: 30478350.
    Citations: 1     Fields:    Translation:HumansAnimalsCells
  9. Oniki K, Watanabe T, Kudo M, Izuka T, Ono T, Matsuda K, Sakamoto Y, Nagaoka K, Imafuku T, Ishima Y, Watanabe H, Maruyama T, Otake K, Ogata Y, Saruwatari J. Modeling of the Weight Status and Risk of Nonalcoholic Fatty Liver Disease in Elderly Individuals: The Potential Impact of the Disulfide Bond-Forming Oxidoreductase A-Like Protein (DsbA-L) Polymorphism on the Weight Status. CPT Pharmacometrics Syst Pharmacol. 2018 06; 7(6):384-393. PMID: 29569850.
    Citations: 1     Fields:    Translation:HumansPHPublic Health
  10. Oshiro S, Ishima Y, Maeda H, Honda N, Bi J, Kinoshita R, Ikeda M, Iwao Y, Imafuku T, Nishida K, Miyamura S, Watanabe H, Otagiri M, Maruyama T. Dual Therapeutic Effects of an Albumin-Based Nitric Oxide Donor on 2 Experimental Models of Chronic Kidney Disease. J Pharm Sci. 2018 03; 107(3):848-855. PMID: 29074377.
    Citations: 3     Fields:    Translation:HumansAnimalsCells
  11. Watanabe H, Sugimoto R, Ikegami K, Enoki Y, Imafuku T, Fujimura R, Bi J, Nishida K, Sakaguchi Y, Murata M, Maeda H, Hirata K, Jingami S, Ishima Y, Tanaka M, Matsushita K, Komaba H, Fukagawa M, Otagiri M, Maruyama T. Parathyroid hormone contributes to the down-regulation of cytochrome P450 3A through the cAMP/PI3K/PKC/PKA/NF-?B signaling pathway in secondary hyperparathyroidism. Biochem Pharmacol. 2017 12 01; 145:192-201. PMID: 28843775.
    Citations:    Fields:    Translation:HumansAnimalsCells
  12. Enoki Y, Watanabe H, Arake R, Fujimura R, Ishiodori K, Imafuku T, Nishida K, Sugimoto R, Nagao S, Miyamura S, Ishima Y, Tanaka M, Matsushita K, Komaba H, Fukagawa M, Otagiri M, Maruyama T. Potential therapeutic interventions for chronic kidney disease-associated sarcopenia via indoxyl sulfate-induced mitochondrial dysfunction. J Cachexia Sarcopenia Muscle. 2017 Oct; 8(5):735-747. PMID: 28608457.
    Citations: 20     Fields:    Translation:HumansAnimalsCells
  13. Watanabe H, Imafuku T, Otagiri M, Maruyama T. Clinical Implications Associated With the Posttranslational Modification-Induced Functional Impairment of Albumin in Oxidative Stress-Related Diseases. J Pharm Sci. 2017 09; 106(9):2195-2203. PMID: 28302542.
    Citations: 6     Fields:    Translation:HumansAnimalsCells
  14. Sugimoto R, Watanabe H, Ikegami K, Enoki Y, Imafuku T, Sakaguchi Y, Murata M, Nishida K, Miyamura S, Ishima Y, Tanaka M, Matsushita K, Komaba H, Fukagawa M, Otagiri M, Maruyama T. Down-regulation of ABCG2, a urate exporter, by parathyroid hormone enhances urate accumulation in secondary hyperparathyroidism. Kidney Int. 2017 03; 91(3):658-670. PMID: 27988213.
    Citations: 5     Fields:    Translation:HumansAnimalsCells
  15. Shibata A, Ishima Y, Ikeda M, Sato H, Imafuku T, Chuang VTG, Ouchi Y, Abe T, Watanabe H, Ishida T, Otagiri M, Maruyama T. Human serum albumin hydropersulfide is a potent reactive oxygen species scavenger in oxidative stress conditions such as chronic kidney disease. Biochem Biophys Res Commun. 2016 Oct 21; 479(3):578-583. PMID: 27666483.
    Citations: 2     Fields:    Translation:HumansAnimals
  16. Enoki Y, Watanabe H, Arake R, Sugimoto R, Imafuku T, Tominaga Y, Ishima Y, Kotani S, Nakajima M, Tanaka M, Matsushita K, Fukagawa M, Otagiri M, Maruyama T. Indoxyl sulfate potentiates skeletal muscle atrophy by inducing the oxidative stress-mediated expression of myostatin and atrogin-1. Sci Rep. 2016 08 23; 6:32084. PMID: 27549031.
    Citations: 29     Fields:    Translation:AnimalsCells
  17. Miyamura S, Imafuku T, Anraku M, Taguchi K, Yamasaki K, Tominaga Y, Maeda H, Ishima Y, Watanabe H, Otagiri M, Maruyama T. Comparison of Posttranslational Modification and the Functional Impairment of Human Serum Albumin in Commercial Preparations. J Pharm Sci. 2016 Mar; 105(3):1043-9. PMID: 26928399.
    Citations: 5     Fields:    Translation:HumansCells
  18. Tanaka M, Miyamura S, Imafuku T, Tominaga Y, Maeda H, Anraku M, Yamasaki K, Kadowaki D, Ishima Y, Watanabe H, Okuda T, Itoh K, Matsushita K, Fukagawa M, Otagiri M, Maruyama T. Effect of a Ferric Citrate Formulation, a Phosphate Binder, on Oxidative Stress in Chronic Kidney Diseases-Mineral and Bone Disorder Patients Receiving Hemodialysis: A Pilot Study. Biol Pharm Bull. 2016; 39(6):1000-6. PMID: 27251502.
    Citations:    Fields:    Translation:Humans
  19. Nishida K, Watanabe H, Ogaki S, Kodama A, Tanaka R, Imafuku T, Ishima Y, Chuang VT, Toyoda M, Kondoh M, Wu Q, Fukagawa M, Otagiri M, Maruyama T. Renoprotective effect of long acting thioredoxin by modulating oxidative stress and macrophage migration inhibitory factor against rhabdomyolysis-associated acute kidney injury. Sci Rep. 2015 Sep 28; 5:14471. PMID: 26412311.
    Citations: 8     Fields:    Translation:AnimalsCells
  20. Anraku M, Tanaka M, Hiraga A, Nagumo K, Imafuku T, Maezaki Y, Iohara D, Uekama K, Watanabe H, Hirayama F, Maruyama T, Otagiri M. Effects of chitosan on oxidative stress and related factors in hemodialysis patients. Carbohydr Polym. 2014 Nov 04; 112:152-7. PMID: 25129729.
    Citations: 4     Fields:    Translation:HumansCTClinical Trials
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.