Harvard Catalyst Profiles

Contact, publication, and social network information about Harvard faculty and fellows.

Miranda Machacek, M.D.


Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Machacek ME, Gogakos T, Fletcher MC, Lunderville KA, Swoboda KJ, Sohani AR. Unusual inclusions in cerebrospinal fluid macrophages of spinal muscular atrophy patients treated with nusinersen. Int J Lab Hematol. 2021 06; 43(3):e104-e106. PMID: 33201586.
    Citations: 3     Fields:    Translation:HumansCells
  2. Machacek M, Fields PE, Slawson C. A proteolytic method for evaluating O-GlcNAcylation on proteins of similar molecular weight to antibody heavy chain after immunoprecipitation. Anal Biochem. 2020 12 15; 611:114001. PMID: 33129762.
    Citations:    Fields:    Translation:HumansCells
  3. Machacek M, Saunders H, Zhang Z, Tan EP, Li J, Li T, Villar MT, Artigues A, Lydic T, Cork G, Slawson C, Fields PE. Elevated O-GlcNAcylation enhances pro-inflammatory Th17 function by altering the intracellular lipid microenvironment. J Biol Chem. 2019 05 31; 294(22):8973-8990. PMID: 31010828.
    Citations: 18     Fields:    Translation:HumansAnimalsCells
  4. Machacek M, Slawson C, Fields PE. O-GlcNAc: a novel regulator of immunometabolism. J Bioenerg Biomembr. 2018 06; 50(3):223-229. PMID: 29404877; PMCID: PMC6408937.
    Citations: 8     Fields:    Translation:HumansAnimalsCells
  5. Tan EP, McGreal SR, Graw S, Tessman R, Koppel SJ, Dhakal P, Zhang Z, Machacek M, Zachara NE, Koestler DC, Peterson KR, Thyfault JP, Swerdlow RH, Krishnamurthy P, DiTacchio L, Apte U, Slawson C. Sustained O-GlcNAcylation reprograms mitochondrial function to regulate energy metabolism. J Biol Chem. 2017 09 08; 292(36):14940-14962. PMID: 28739801.
    Citations: 32     Fields:    Translation:HumansAnimalsCells
  6. Lanza C, Tan EP, Zhang Z, Machacek M, Brinker AE, Azuma M, Slawson C. Reduced O-GlcNAcase expression promotes mitotic errors and spindle defects. Cell Cycle. 2016 05 18; 15(10):1363-75. PMID: 27070276; PMCID: PMC4889296.
    Citations: 14     Fields:    Translation:HumansCells
  7. Ethen CM, Machacek M, Prather B, Tatge T, Yu H, Wu ZL. Nonradioactive glycosyltransferase and sulfotransferase assay to study glycosaminoglycan biosynthesis. Methods Mol Biol. 2015; 1229:431-41. PMID: 25325970.
    Citations: 1     Fields:    Translation:HumansAnimals
  8. Prather B, Ethen CM, Machacek M, Wu ZL. Golgi-resident PAP-specific 3'-phosphatase-coupled sulfotransferase assays. Anal Biochem. 2012 Apr 01; 423(1):86-92. PMID: 22289690.
    Citations: 4     Fields:    Translation:HumansCells
  9. Wu ZL, Ethen CM, Prather B, Machacek M, Jiang W. Universal phosphatase-coupled glycosyltransferase assay. Glycobiology. 2011 Jun; 21(6):727-33. PMID: 21081508.
    Citations: 35     Fields:    Translation:Humans
  10. Xiao Y, Machacek M, Lee K, Kuzuyama T, Liu P. Prenyltransferase substrate binding pocket flexibility and its application in isoprenoid profiling. Mol Biosyst. 2009 Sep; 5(9):913-7. PMID: 19668852.
    Citations: 3     Fields:    Translation:Cells
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.