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Schwarzschild, Michael
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Michael A. Schwarzschild, M.D., Ph.D.
Title
Julieanne Dorn Professor of Neurology
Institution
Massachusetts General Hospital
Department
Neurology
Address
Massachusetts General Hospital
MassGeneral Inst. for Neurodegenerative Disease-Rm 3002
114 16th Street
Charlestown MA 02129
Phone
617/724-1480
Fax
617/726-4899
vCard
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awards and honors
|
keywords
|
webpage
|
research activities and funding
|
featured videos
|
selected publications
|
Biography
awards and honors
1985
Markey Fellowship award, HMS
1987 - 1988
Ryan Fellowship award, HMS
1994 - 1999
Clinical Investigator Development Award, NIH
1999 - 2002
George C. Cotzias Memorial Fellowship Award, APDA
2001
Fox Foundation inaugural research grant program award Awardee
2002 - 2005
Paul Beeson Faculty Scholar in Aging Research Program awardee, AFAR
2005 - 2006
Dorothy Dillon Eweson Lectureships, AFAR
2006
Partners in Excellence Award (mentoring)
2012 - 2018
Elected Chair, Executive Committee, Parkinson Study Group
2013
Member, Linked Clinical Trials Committee, Cure Parkinson's Trust
2018 - 2024
Elected Chair, Executive Committee, Parkinson Study Group
2017 - 2019
Scientific Advisory Board member, Michael J. Fox Foundation for Parkinson's Research
Overview
keywords
Parkinson's Disease
webpage
MGH/MIND Molecular Neurobiology Lab
Parkinson Study Group
Research
research activities and funding
The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can
login
to make corrections and additions.
Most Recent
|
List All
R01NS110879
(SCHWARZSCHILD, MICHAEL A)
Aug 1, 2019 - May 31, 2024
NIH
Urate-LRRK2 interactions in Parkinson's disease
Role: Principal Investigator
R13NS111953
(SCHWARZSCHILD, MICHAEL A)
Apr 1, 2019 - Mar 31, 2022
NIH
2019 Parkinson Study Group Symposium and Training
Role: Principal Investigator
U01NS107009
(SCHWARZSCHILD, MICHAEL A)
Jul 1, 2018 - Apr 30, 2023
NIH
Tele-Health Extension for Phase 3 Parkinson's Disease Trial Cohorts
Role: Principal Investigator
U13NS103523
(SCHWARZSCHILD, MICHAEL A)
Jul 1, 2017 - Jun 30, 2018
NIH
2017 Parkinson Study Group Symposium and Training
Role: Principal Investigator
R13NS098746
(SCHWARZSCHILD, MICHAEL A)
Aug 1, 2016 - Jul 31, 2017
NIH
2016 Parkinson Study Group Symposium and Training
Role: Principal Investigator
(Michael Schwarzschild)
Jan 1, 2016 - Dec 31, 2019
Michael J. Fox Foundation
Blood Sampling for Future Biomarker Research
U01NS090259
(SCHWARZSCHILD, MICHAEL A)
Sep 1, 2015 - Jun 30, 2020
NIH
Phase 3 trial of inosine for Parkinson's disease CCC
Role: Principal Investigator
(Michael Schwarzschild)
Nov 1, 2014 - Oct 31, 2017
Target ALS
Preclinical Foundation of Urate-Elevating Therapy for ALS
Role: Principal Investigator
R13NS090879
(SCHWARZSCHILD, MICHAEL A)
Sep 22, 2014 - Aug 31, 2015
NIH
2014 Parkinson Study Group Symposium and Training
Role: Principal Investigator
(Michael Schwarzschild)
Jun 14, 2014 - Jul 12, 2017
Michael J. Fox Foundation
Purine Biomarkers of LRRK2 PD
R13NS086328
(SCHWARZSCHILD, MICHAEL A)
Sep 23, 2013 - Aug 31, 2014
NIH
2013 Parkinson's Study Group Symposium
Role: Principal Investigator
PDF-APT-1407
(Michael Schwarzschild)
Jul 1, 2013 - Jun 30, 2017
Parkinson’s Disease Foundation
Parkinson Study Group (PSG) -- PDF’s Advancing Parkinson’s Therapies Innovations award
R21NS084710
(SCHWARZSCHILD, MICHAEL A)
Jul 1, 2013 - Jun 30, 2015
NIH
Role of urate in protecting mitochondrial function in the brain
Role: Principal Investigator
R21NS058324
(SCHWARZSCHILD, MICHAEL A)
Jun 15, 2009 - May 31, 2011
NIH
Uric Acid:novel therapeutic target for Parkinson's Disease
Role: Principal Investigator
K24NS060991
(SCHWARZSCHILD, MICHAEL A)
Sep 3, 2008 - Feb 28, 2014
NIH
Pursuing purine pathways to clinical trials for Parkinson's disease
Role: Principal Investigator
R13NS055597
(SCHWARZSCHILD, MICHAEL A)
Apr 3, 2006 - Mar 31, 2007
NIH
Targeting Adenosine A2A Receptors in Parkinson's Disease
Role: Principal Investigator
R01NS054978
(SCHWARZSCHILD, MICHAEL A)
Apr 1, 2006 - Mar 31, 2012
NIH
Translational Foundation of Adenosine Antagonist Use for Dyskinesias
Role: Principal Investigator
R13NS044990
(SCHWARZSCHILD, MICHAEL A)
Sep 1, 2002 - Aug 31, 2003
NIH
Translating A2A Receptor Biology into Novel PD Therapy
Role: Principal Investigator
R01DA013508
(SCHWARZSCHILD, MICHAEL A)
Jul 25, 2001 - May 31, 2006
NIH
A2A Adenosine Receptors in Psychostimulant Sensitization
Role: Principal Investigator
R01ES010804
(SCHWARZSCHILD, MICHAEL A)
May 1, 2001 - Apr 30, 2006
NIH
Novel Neuroprotection by Caffeine in Parkinson's Disease
Role: Principal Investigator
R03AG018167
(SCHWARZSCHILD, MICHAEL A)
Sep 1, 2000 - Aug 31, 2001
NIH
A2A ADENOSINE RECEPTOR--A NOVEL ROLE IN NEUROPROTECTION
Role: Principal Investigator
K08NS001729
(SCHWARZSCHILD, MICHAEL A)
Jul 1, 1994 - Jun 30, 1999
NIH
RAS AND NEURONAL GENE REGULATION BY CNTF
Role: Principal Investigator
R01DA007496
(SCHWARZSCHILD, MICHAEL A)
Aug 1, 1992 - Aug 31, 2001
NIH
ADENOSINE A2 RECEPTORS AND PSYCHOSTIMULANT INTERACTIONS
Role: Principal Investigator
M01RR001066
(SLAVIN, PETER L)
Feb 1, 1978 - May 31, 2008
NIH
General Clinical Research Center
Role: Co-Principal Investigator
Featured Content
Featured Videos
Bibliographic
selected publications
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can
login
to make corrections and additions.
Newest
|
Oldest
|
Most Cited
|
Most Discussed
|
Timeline
|
Field Summary
|
Plain Text
PMC Citations
indicate the number of times the publication was cited by articles in PubMed Central, and the
Altmetric
score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.)
Fields
are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication.
Translation
tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
Walk D, Nicholson K, Locatelli E, Chan J,
Macklin EA
, Ferment V, Manousakis G, Chase M, Connolly M, Dagostino D, Hall M, Ostrow J, Pothier L, Lieberman C, Gelevski D, Randall R, Sherman AV, Steinhart E, Grasso Walker D, Walker J, Yu H, Wills AM,
Schwarzschild MA
, Beukenhorst AL, Onnela JP,
Berry JD
,
Cudkowicz ME
,
Paganoni S
. Randomized trial of inosine for urate elevation in amyotrophic lateral sclerosis. Muscle Nerve. 2023 Feb 25.
PMID:
36840949
.
Citations:
Fields:
Neu
Neurology
Phy
Physiology
Di Luca DG,
Macklin EA
, Hodgeman K, Lopez G, Pothier L, Callahan KF, Lowell J, Chan J,
Videnovic A
, Lungu C, Lang AE, Litvan I,
Schwarzschild MA
, Simuni T. Enrollment of Participants From Marginalized Racial and Ethnic Groups: A Comparative Assessment of the STEADY-PD III and SURE-PD3 Trials. Neurol Clin Pract. 2023 Feb; 13(1):e200113.
PMID:
36865634
; PMCID:
PMC9973288
.
Citations:
Liu G, Ni C, Zhan J, Li W, Luo J, Liao Z,
Locascio JJ
, Xian W, Chen L, Pei Z, Corvol JC, Maple-Grødem J, Campbell MC, Elbaz A, Lesage S, Brice A,
Hung AY
,
Schwarzschild MA
,
Hayes MT
, Wills AM, Ravina B, Shoulson I, Taba P, Kõks S, Beach TG, Cormier-Dequaire F, Alves G, Tysnes OB, Perlmutter JS, Heutink P, van Hilten JJ, Barker RA, Williams-Gray CH,
Scherzer CR
. Mitochondrial haplogroups and cognitive progression in Parkinson's disease. Brain. 2023 01 05; 146(1):42-49.
PMID:
36343661
.
Citations:
1
Fields:
Bra
Brain
Neu
Neurology
Translation:
Humans
Cells
Patterson CG, Joslin E, Gil AB, Spigle W, Nemet T, Chahine L, Christiansen CL, Melanson E, Kohrt WM, Mancini M, Josbeno D, Balfany K, Griffith G, Dunlap MK, Lamotte G, Suttman E, Larson D, Branson C, McKee KE, Goelz L, Poon C, Tilley B, Kang UJ, Tansey MG, Luthra N, Tanner CM, Haus JM, Fantuzzi G, McFarland NR, Gonzalez-Latapi P, Foroud T, Motl R,
Schwarzschild MA
, Simuni T, Marek K, Naito A, Lungu C, Corcos DM. Study in Parkinson's disease of exercise phase 3 (SPARX3): study protocol for a randomized controlled trial. Trials. 2022 Oct 06; 23(1):855.
PMID:
36203214
; PMCID:
PMC9535216
.
Citations:
1
Fields:
Med
Medicine (General)
The
Therapeutics
Translation:
Humans
CT
Clinical Trials
Crotty GF
,
Schwarzschild MA
. What to Test in Parkinson Disease Prevention Trials? Repurposed, Low-Risk, and Gene-Targeted Drugs. Neurology. 2022 08 16; 99(7 Suppl 1):34-41.
PMID:
35970592
.
Citations:
Fields:
Neu
Neurology
Translation:
Humans
Berg D,
Crotty GF
, Keavney JL,
Schwarzschild MA
, Simuni T, Tanner C. Path to Parkinson Disease Prevention: Conclusion and Outlook. Neurology. 2022 08 16; 99(7 Suppl 1):76-83.
PMID:
35970586
.
Citations:
1
Fields:
Neu
Neurology
Translation:
Humans
Crotty GF
, Keavney JL, Alcalay RN, Marek K,
Marshall GA
,
Rosas HD
,
Schwarzschild MA
. Planning for Prevention of Parkinson Disease: Now Is the Time. Neurology. 2022 08 16; 99(7 Suppl 1):1-9.
PMID:
36219787
.
Citations:
Fields:
Neu
Neurology
Translation:
Humans
Molsberry SA, Hughes KC,
Schwarzschild MA
,
Ascherio A
. Who to Enroll in Parkinson Disease Prevention Trials? The Case for Composite Prodromal Cohorts. Neurology. 2022 08 16; 99(7 Suppl 1):26-33.
PMID:
35970591
; PMCID:
PMC9259088
.
Citations:
Fields:
Neu
Neurology
Translation:
Humans
Zhang X, Molsberry SA,
Schwarzschild MA
,
Ascherio A
, Gao X. Association of Diet and Physical Activity With All-Cause Mortality Among Adults With Parkinson Disease. JAMA Netw Open. 2022 08 01; 5(8):e2227738.
PMID:
35984656
; PMCID:
PMC9391952
.
Citations:
Fields:
Med
Medicine (General)
Translation:
Humans
Luo S, Zou H, Stebbins GT,
Schwarzschild MA
,
Macklin EA
, Chan J, Oakes D, Simuni T, Goetz CG. Dissecting the Domains of Parkinson's Disease: Insights from Longitudinal Item Response Theory Modeling. Mov Disord. 2022 09; 37(9):1904-1914.
PMID:
35841312
; PMCID:
PMC9897939
.
Citations:
Fields:
Neu
Neurology
Cai W,
Srivastava P
, Feng D, Lin Y, Vanderburg CR, Xu Y, Mclean P,
Frosch MP
,
Fisher DE
,
Schwarzschild MA
, Chen X. Melanocortin 1 receptor activation protects against alpha-synuclein pathologies in models of Parkinson's disease. Mol Neurodegener. 2022 02 23; 17(1):16.
PMID:
35197079
; PMCID:
PMC8867846
.
Citations:
Fields:
Mol
Molecular Biology
Neu
Neurology
Translation:
Humans
Animals
Cells
Sanchez AV, Ison JM, Hemley H, Willis A, Siddiqi B,
Macklin EA
, Ulysse C, Reynolds M,
Schwarzschild MA
, Jackson JD. Designing the Fostering Inclusivity in Research Engagement for Underrepresented Populations in Parkinson's Disease study. Contemp Clin Trials. 2022 04; 115:106713.
PMID:
35202842
.
Citations:
Fields:
Med
Medicine (General)
The
Therapeutics
Translation:
Humans
Zhang X, Molsberry SA,
Yeh TS
,
Cassidy A
,
Schwarzschild MA
,
Ascherio A
, Gao X. Intake of Flavonoids and Flavonoid-Rich Foods and Mortality Risk Among Individuals With Parkinson Disease: A Prospective Cohort Study. Neurology. 2022 03 08; 98(10):e1064-e1076.
PMID:
35082171
; PMCID:
PMC8967390
.
Citations:
1
Fields:
Neu
Neurology
Translation:
Humans
Page A, Yung N, Auinger P, Venuto C, Glidden A,
Macklin E
, Omberg L,
Schwarzschild MA
, Dorsey ER. A Smartphone Application as an Exploratory Endpoint in a Phase 3 Parkinson's Disease Clinical Trial: A Pilot Study. Digit Biomark. 2022; 6(1):1-8.
PMID:
35224425
; PMCID:
PMC8832247
.
Citations:
Macklin EA
,
Ascherio A
,
Schwarzschild MA
. Effect of Urate-Elevating Inosine on Progression of Early Parkinson Disease-Reply. JAMA. 2022 01 04; 327(1):85-86.
PMID:
34982121
.
Citations:
Fields:
Med
Medicine (General)
Translation:
Humans
Darweesh SKL, De Vries NM, Helmich RC, Verbeek MM,
Schwarzschild MA
, Bloem BR. Inhibition of Neuroinflammation May Mediate the Disease-Modifying Effects of Exercise: Implications for Parkinson's Disease. J Parkinsons Dis. 2022; 12(5):1419-1422.
PMID:
35466957
; PMCID:
PMC9398068
.
Citations:
Fields:
Neu
Neurology
Translation:
Humans
Schwarzschild MA
,
Ascherio A
, Casaceli C,
Curhan GC
, Fitzgerald R, Kamp C, Lungu C,
Macklin EA
, Marek K, Mozaffarian D, Oakes D, Rudolph A, Shoulson I,
Videnovic A
, Scott B, Gauger L, Aldred J, Bixby M, Ciccarello J, Gunzler SA, Henchcliffe C, Brodsky M, Keith K, Hauser RA, Goetz C, LeDoux MS, Hinson V, Kumar R, Espay AJ, Jimenez-Shahed J, Hunter C, Christine C, Daley A, Leehey M, de Marcaida JA, Friedman JH,
Hung A
, Bwala G, Litvan I,
Simon DK
, Simuni T, Poon C, Schiess MC, Chou K, Park A, Bhatti D, Peterson C, Criswell SR, Rosenthal L, Durphy J, Shill HA, Mehta SH, Ahmed A, Deik AF, Fang JY, Stover N, Zhang L, Dewey RB, Gerald A, Boyd JT, Houston E, Suski V, Mosovsky S, Cloud L, Shah BB, Saint-Hilaire M, James R, Zauber SE, Reich S, Shprecher D, Pahwa R, Langhammer A, LaFaver K, LeWitt PA, Kaminski P, Goudreau J, Russell D, Houghton DJ, Laroche A, Thomas K, McGraw M, Mari Z, Serrano C, Blindauer K, Rabin M, Kurlan R, Morgan JC, Soileau M, Ainslie M, Bodis-Wollner I, Schneider RB, Waters C, Ratel AS, Beck CA, Bolger P, Callahan KF,
Crotty GF
, Klements D, Kostrzebski M,
McMahon GM
, Pothier L,
Waikar SS
, Lang A, Mestre T. Effect of Urate-Elevating Inosine on Early Parkinson Disease Progression: The SURE-PD3 Randomized Clinical Trial. JAMA. 2021 09 14; 326(10):926-939.
PMID:
34519802
; PMCID:
PMC8441591
.
Citations:
7
Fields:
Med
Medicine (General)
Translation:
Humans
CT
Clinical Trials
Lungu C, Cedarbaum JM, Dawson TM, Dorsey ER, Faraco C, Federoff HJ, Fiske B, Fox R, Goldfine AM, Kieburtz K,
Macklin EA
, Matthews H, Rafaloff G, Saunders-Pullman R, Schor NF,
Schwarzschild MA
, Sieber BA, Simuni T, Surmeier DJ, Tamiz A, Werner MH, Wright CB, Wyse R. Seeking progress in disease modification in Parkinson disease. Parkinsonism Relat Disord. 2021 09; 90:134-141.
PMID:
34561166
.
Citations:
1
Fields:
Neu
Neurology
Translation:
Humans
Bjornevik K
, O'Reilly EJ, Molsberry S, Kolonel LN, Le Marchand L,
Paganoni S
,
Schwarzschild MA
, Benkert P, Kuhle J,
Ascherio A
. Prediagnostic Neurofilament Light Chain Levels in Amyotrophic Lateral Sclerosis. Neurology. 2021 Aug 11.
PMID:
34380747
; PMCID:
PMC8575132
.
Citations:
Fields:
Neu
Neurology
Flores-Torres MH, Hughes KC, Molsberry S, Gao X,
Kang JH
,
Schwarzschild MA
,
Ascherio A
. Cognitive function in men with non-motor features of Parkinson's disease. BMJ Neurol Open. 2021; 3(1):e000112.
PMID:
34250483
; PMCID:
PMC8217956
.
Citations:
Liu G, Peng J, Liao Z,
Locascio JJ
, Corvol JC, Zhu F,
Dong X
, Maple-Grødem J, Campbell MC, Elbaz A, Lesage S, Brice A, Mangone G,
Growdon JH
,
Hung AY
,
Schwarzschild MA
,
Hayes MT
, Wills AM,
Herrington TM
, Ravina B, Shoulson I, Taba P, Kõks S, Beach TG, Cormier-Dequaire F, Alves G, Tysnes OB, Perlmutter JS, Heutink P,
Amr SS
, van Hilten JJ, Kasten M, Mollenhauer B, Trenkwalder C, Klein C, Barker RA, Williams-Gray CH, Marinus J,
Scherzer CR
. Genome-wide survival study identifies a novel synaptic locus and polygenic score for cognitive progression in Parkinson's disease. Nat Genet. 2021 06; 53(6):787-793.
PMID:
33958783
; PMCID:
PMC8459648
.
Citations:
11
Fields:
Gen
Genetics
Translation:
Humans
Cells
Mestre TA,
Macklin EA
,
Ascherio A
, Ferreira JJ, Lang AE,
Schwarzschild MA
. Expectations of Benefit in a Trial of a Candidate Disease-Modifying Treatment for Parkinson Disease. Mov Disord. 2021 08; 36(8):1964-1967.
PMID:
33942376
.
Citations:
1
Fields:
Neu
Neurology
Translation:
Humans
Peters OM, Weiss A, Metterville J, Song L, Logan R, Smith GA,
Schwarzschild MA
, Mueller C, Brown RH, Freeman M. Genetic diversity of axon degenerative mechanisms in models of Parkinson's disease. Neurobiol Dis. 2021 07; 155:105368.
PMID:
33892050
; PMCID:
PMC8292971
.
Citations:
3
Fields:
Neu
Neurology
Translation:
Animals
Cells
Zhang X, Molsberry SA,
Pavlova M
,
Schwarzschild MA
,
Ascherio A
, Gao X. Association of Sleepwalking and REM Sleep Behavior Disorder With Parkinson Disease in Men. JAMA Netw Open. 2021 04 01; 4(4):e215713.
PMID:
33847749
.
Citations:
3
Fields:
Med
Medicine (General)
Translation:
Humans
Tanner CM, Cummings SR,
Schwarzschild MA
, Brown EG, Dorsey ER, Espay AJ, Galifianakis NB, Goldman SM, Litvan I, Luthra N, McFarland NR, Mitchell KT, Standaert DG, Bauer DC, Greenspan SL, Beck JC, Lyles KW. The TOPAZ study: a home-based trial of zoledronic acid to prevent fractures in neurodegenerative parkinsonism. NPJ Parkinsons Dis. 2021 Mar 01; 7(1):16.
PMID:
33649343
.
Citations:
1
Simuni T, Fiske B, Merchant K, Coffey CS, Klingner E, Caspell-Garcia C, Lafontant DE, Matthews H, Wyse RK, Brundin P,
Simon DK
,
Schwarzschild M
, Weiner D, Adams J, Venuto C, Dawson TM, Baker L, Kostrzebski M, Ward T, Rafaloff G. Efficacy of Nilotinib in Patients With Moderately Advanced Parkinson Disease: A Randomized Clinical Trial. JAMA Neurol. 2021 03 01; 78(3):312-320.
PMID:
33315105
; PMCID:
PMC7737147
.
Citations:
24
Fields:
Neu
Neurology
Translation:
Humans
Hughes KC, Gao X, Baker JM,
Stephen CD
, Kim IY,
Valeri L
,
Schwarzschild MA
,
Ascherio A
. Non-Motor Features of Parkinson's Disease in Women. J Parkinsons Dis. 2021; 11(3):1237-1246.
PMID:
33935102
.
Citations:
Fields:
Neu
Neurology
Translation:
Humans
Schneider RB, Omberg L,
Macklin EA
, Daeschler M, Bataille L, Anthwal S, Myers TL, Baloga E, Duquette S, Snyder P, Amodeo K, Tarolli CG, Adams JL, Callahan KF, Gottesman J, Kopil CM, Lungu C,
Ascherio A
, Beck JC, Biglan K, Espay AJ, Tanner C, Oakes D, Shoulson I, Novak D, Kayson E, Ray Dorsey E, Mangravite L,
Schwarzschild MA
, Simuni T. Design of a virtual longitudinal observational study in Parkinson's disease (AT-HOME PD). Ann Clin Transl Neurol. 2021 02; 8(2):308-320.
PMID:
33350601
.
Citations:
4
Fields:
Neu
Neurology
Translation:
Humans
Cells
Chen JF,
Schwarzschild MA
. Do caffeine and more selective adenosine A2A receptor antagonists protect against dopaminergic neurodegeneration in Parkinson's disease? Parkinsonism Relat Disord. 2020 11; 80 Suppl 1:S45-S53.
PMID:
33349580
.
Citations:
4
Fields:
Neu
Neurology
Translation:
Humans
Animals
Andronesi OC
, Nicholson K, Jafari-Khouzani K, Bogner W, Wang J, Chan J,
Macklin EA
, Levine-Weinberg M, Breen C,
Schwarzschild MA
,
Cudkowicz M
,
Rosen BR
,
Paganoni S
,
Ratai EM
. Imaging Neurochemistry and Brain Structure Tracks Clinical Decline and Mechanisms of ALS in Patients. Front Neurol. 2020; 11:590573.
PMID:
33343494
.
Citations:
5
Hung AY
,
Schwarzschild MA
. Approaches to Disease Modification for Parkinson's Disease: Clinical Trials and Lessons Learned. Neurotherapeutics. 2020 10; 17(4):1393-1405.
PMID:
33205384
; PMCID:
PMC7851299
.
Citations:
5
Fields:
Neu
Neurology
Translation:
Humans
Crotty GF
, Lo RY,
Schwarzschild MA
. If LRRK2 Set the Fire, Can Nonsteroidal Anti-inflammatory Drugs Wet the Flames? Mov Disord. 2020 10; 35(10):1727-1730.
PMID:
33068466
.
Citations:
2
Fields:
Neu
Neurology
Translation:
Humans
Ma C
, Molsberry S, Li Y,
Schwarzschild M
,
Ascherio A
, Gao X. Dietary nicotine intake and risk of Parkinson disease: a prospective study. Am J Clin Nutr. 2020 10 01; 112(4):1080-1087.
PMID:
32725131
; PMCID:
PMC7528555
.
Citations:
1
Fields:
Nut
Nutritional Sciences
Translation:
Humans
PH
Public Health
Crotty GF
, Maciuca R,
Macklin EA
, Wang J, Montalban M, Davis SS, Alkabsh JI,
Bakshi R
, Chen X,
Ascherio A
, Astarita G, Huntwork-Rodriguez S,
Schwarzschild MA
. Association of caffeine and related analytes with resistance to Parkinson disease among LRRK2 mutation carriers: A metabolomic study. Neurology. 2020 12 15; 95(24):e3428-e3437.
PMID:
32999056
; PMCID:
PMC7836665
.
Citations:
10
Fields:
Neu
Neurology
Translation:
Humans
Bjornevik K
, O'Reilly ÉJ,
Cortese M
,
Furtado JD
, Kolonel LN, Le Marchand L, Mccullough ML,
Paganoni S
,
Schwarzschild MA
, Shadyab AH,
Manson JE
,
Ascherio A
. Pre-diagnostic plasma lipid levels and the risk of amyotrophic lateral sclerosis. Amyotroph Lateral Scler Frontotemporal Degener. 2021 02; 22(1-2):133-143.
PMID:
32985910
; PMCID:
PMC8004541
.
Citations:
4
Fields:
Neu
Neurology
Translation:
Humans
Molsberry S,
Bjornevik K
, Hughes KC,
Healy B
,
Schwarzschild M
,
Ascherio A
. Diet pattern and prodromal features of Parkinson disease. Neurology. 2020 10 13; 95(15):e2095-e2108.
PMID:
32817391
; PMCID:
PMC7713746
.
Citations:
6
Fields:
Neu
Neurology
Translation:
Humans
Crotty GF
,
Schwarzschild MA
. Chasing Protection in Parkinson's Disease: Does Exercise Reduce Risk and Progression? Front Aging Neurosci. 2020; 12:186.
PMID:
32636740
.
Citations:
4
Huh YE, Chiang MSR,
Locascio JJ
, Liao Z, Liu G, Choudhury K, Kuras YI, Tuncali I,
Videnovic A
,
Hunt AL
,
Schwarzschild MA
,
Hung AY
,
Herrington TM
,
Hayes MT
,
Hyman BT
, Wills AM,
Gomperts SN
,
Growdon JH
, Sardi SP,
Scherzer CR
. ß-Glucocerebrosidase activity in GBA-linked Parkinson disease: The type of mutation matters. Neurology. 2020 08 11; 95(6):e685-e696.
PMID:
32540937
; PMCID:
PMC7455354
.
Citations:
11
Fields:
Neu
Neurology
Translation:
Humans
Espay AJ, Kalia LV, Gan-Or Z, Williams-Gray CH, Bedard PL, Rowe SM, Morgante F, Fasano A, Stecher B, Kauffman MA, Farrer MJ, Coffey CS,
Schwarzschild MA
, Sherer T, Postuma RB, Strafella AP, Singleton AB, Barker RA, Kieburtz K, Olanow CW, Lozano A, Kordower JH, Cedarbaum JM, Brundin P, Standaert DG, Lang AE. Disease modification and biomarker development in Parkinson disease: Revision or reconstruction? Neurology. 2020 03 17; 94(11):481-494.
PMID:
32102975
; PMCID:
PMC7220234
.
Citations:
28
Fields:
Neu
Neurology
Translation:
Humans
Alcalay RN, Kehoe C, Shorr E, Battista R, Hall A, Simuni T, Marder K, Wills AM, Naito A, Beck JC,
Schwarzschild MA
, Nance M. Correction: Genetic testing for Parkinson disease: current practice, knowledge, and attitudes among US and Canadian movement disorders specialists. Genet Med. 2020 Feb; 22(2):448.
PMID:
31772350
; PMCID:
PMC7000320
.
Citations:
Fields:
Gen
Genetics
Palacios N, O'Reilly ÉJ,
Schwarzschild MA
,
Ascherio A
. Long-Term Use of Antibiotics and Risk of Parkinson's Disease in the Nurses' Health Study. Parkinsons Dis. 2020; 2020:4038375.
PMID:
32399169
; PMCID:
PMC7201469
.
Citations:
1
Bjornevik K
,
Schwarzschild MA
,
Ascherio A
. Big health data and Parkinson's disease epidemiology: Challenges and opportunities. Parkinsonism Relat Disord. 2020 02; 71:58-59.
PMID:
31948788
.
Citations:
Fields:
Neu
Neurology
Translation:
Humans
Schootemeijer S, van der Kolk NM, Ellis T, Mirelman A, Nieuwboer A, Nieuwhof F,
Schwarzschild MA
, de Vries NM, Bloem BR. Barriers and Motivators to Engage in Exercise for Persons with Parkinson's Disease. J Parkinsons Dis. 2020; 10(4):1293-1299.
PMID:
32925106
.
Citations:
17
Fields:
Neu
Neurology
Translation:
Humans
Hasimoglu YG, Chen X,
Bakshi R
,
Schwarzschild MA
,
Macklin EA
. Does Serum Urate Change as Parkinson's Disease Progresses? J Parkinsons Dis. 2020; 10(4):1571-1576.
PMID:
32773396
.
Citations:
Fields:
Neu
Neurology
Translation:
Humans
Molsberry S,
Bjornevik K
, Hughes KC, Zhang ZJ, Jeanfavre S, Clish C,
Healy B
,
Schwarzschild M
,
Ascherio A
. Plasma Metabolomic Markers of Insulin Resistance and Diabetes and Rate of Incident Parkinson's Disease. J Parkinsons Dis. 2020; 10(3):1011-1021.
PMID:
32250318
.
Citations:
1
Fields:
Neu
Neurology
Translation:
Humans
Bakshi R
,
Macklin EA
,
Hung AY
,
Hayes MT
,
Hyman BT
, Wills AM,
Gomperts SN
,
Growdon JH
,
Ascherio A
,
Scherzer CR
,
Schwarzschild MA
. Associations of Lower Caffeine Intake and Plasma Urate Levels with Idiopathic Parkinson's Disease in the Harvard Biomarkers Study. J Parkinsons Dis. 2020; 10(2):505-510.
PMID:
32250320
.
Citations:
10
Fields:
Neu
Neurology
Translation:
Humans
Shen Y, Li J,
Schwarzschild M
,
Pavlova M
, He S,
Ascherio A
, Wu S, Cui L, Gao X. Plasma urate concentrations and possible REM sleep behavior disorder. Ann Clin Transl Neurol. 2019 12; 6(12):2368-2376.
PMID:
31714690
; PMCID:
PMC6917330
.
Citations:
2
Fields:
Neu
Neurology
Translation:
Humans
CT
Clinical Trials
Hughes KC, Gao X, Molsberry S,
Valeri L
,
Schwarzschild MA
,
Ascherio A
. Physical activity and prodromal features of Parkinson disease. Neurology. 2019 12 03; 93(23):e2157-e2169.
PMID:
31719136
.
Citations:
7
Fields:
Neu
Neurology
Translation:
Humans
Alcalay RN, Kehoe C, Shorr E, Battista R, Hall A, Simuni T, Marder K, Wills AM, Naito A, Beck JC,
Schwarzschild MA
, Nance M. Genetic testing for Parkinson disease: current practice, knowledge, and attitudes among US and Canadian movement disorders specialists. Genet Med. 2020 03; 22(3):574-580.
PMID:
31680121
; PMCID:
PMC7056638
.
Citations:
8
Fields:
Gen
Genetics
Translation:
Humans
Schwarzschild MA
,
Macklin EA
,
Bakshi R
, Battacharyya S, Logan R, Espay AJ,
Hung AY
, Bwala G, Goetz CG, Russell DS, Goudreau JL, Parashos SA, Saint-Hilaire MH, Rudolph A, Hare JM,
Curhan GC
,
Ascherio A
. Sex differences by design and outcome in the Safety of Urate Elevation in PD (SURE-PD) trial. Neurology. 2019 10 01; 93(14):e1328-e1338.
PMID:
31484712
; PMCID:
PMC6814412
.
Citations:
13
Fields:
Neu
Neurology
Translation:
Humans
Bakshi R
,
Macklin EA
,
Schwarzschild MA
. Reply to "Mitochondrial DNA deletions discriminate affected from unaffected LRRK2 mutation carriers". Ann Neurol. 2019 08; 86(2):326-327.
PMID:
31148194
.
Citations:
Fields:
Neu
Neurology
Translation:
Humans
Bjornevik K
, Zhang Z, O'Reilly ÉJ,
Berry JD
, Clish CB, Deik A, Jeanfavre S, Kato I,
Kelly RS
, Kolonel LN, Liang L, Marchand LL, McCullough ML,
Paganoni S
, Pierce KA,
Schwarzschild MA
, Shadyab AH, Wactawski-Wende J, Wang DD, Wang Y,
Manson JE
,
Ascherio A
. Prediagnostic plasma metabolomics and the risk of amyotrophic lateral sclerosis. Neurology. 2019 04 30; 92(18):e2089-e2100.
PMID:
30926684
.
Citations:
15
Fields:
Neu
Neurology
Translation:
Humans
Bakshi R
,
Macklin EA
, Logan R, Zorlu MM,
Xia N
,
Crotty GF
, Zhang E, Chen X,
Ascherio A
,
Schwarzschild MA
. Higher urate in LRRK2 mutation carriers resistant to Parkinson disease. Ann Neurol. 2019 04; 85(4):593-599.
PMID:
30761591
.
Citations:
18
Fields:
Neu
Neurology
Translation:
Humans
Espay AJ, Vizcarra JA, Marsili L, Lang AE,
Simon DK
, Merola A, Josephs KA, Fasano A, Morgante F, Savica R, Greenamyre JT, Cambi F, Yamasaki TR, Tanner CM, Gan-Or Z, Litvan I, Mata IF, Zabetian CP, Brundin P, Fernandez HH, Standaert DG, Kauffman MA,
Schwarzschild MA
, Sardi SP, Sherer T, Perry G, Leverenz JB. Revisiting protein aggregation as pathogenic in sporadic Parkinson and Alzheimer diseases. Neurology. 2019 02 12; 92(7):329-337.
PMID:
30745444
; PMCID:
PMC6382364
.
Citations:
56
Fields:
Neu
Neurology
Translation:
Humans
Ascherio A
,
Schwarzschild MA
. Lifestyle and Parkinson's disease progression. Mov Disord. 2019 01; 34(1):7-8.
PMID:
30653733
.
Citations:
1
Fields:
Neu
Neurology
Translation:
Humans
Bjornevik K
, O'Reilly ÉJ,
Berry JD
, Clish CB, Jeanfavre S, Kato I, Kolonel LN, Le Marchand L, McCullough ML,
Paganoni S
,
Schwarzschild MA
, Talbott EO, Wallace RB, Zhang Z,
Manson JE
,
Ascherio A
. Prediagnostic plasma branched-chain amino acids and the risk of amyotrophic lateral sclerosis. Neurology. 2019 04 30; 92(18):e2081-e2088.
PMID:
30429276
.
Citations:
4
Fields:
Neu
Neurology
Translation:
Humans
Chen X, Umeh CC, Tainsh RE, Feng DD, Maguire M, Zuo F,
Rahimian M
, Logan R, Wang X,
Ascherio A
,
Macklin EA
, Buys ES,
Schwarzschild MA
. Dissociation between urate and blood pressure in mice and in people with early Parkinson's disease. EBioMedicine. 2018 Nov; 37:259-268.
PMID:
30415890
.
Citations:
4
Fields:
Gen
Genetics
Med
Medicine (General)
Translation:
Humans
Animals
Nicholson K, Chan J,
Macklin EA
, Levine-Weinberg M, Breen C,
Bakshi R
, Grasso DL, Wills AM, Jahandideh S, Taylor AA, Beaulieu D, Ennist DL,
Andronesi O
,
Ratai EM
,
Schwarzschild MA
,
Cudkowicz M
,
Paganoni S
. Pilot trial of inosine to elevate urate levels in amyotrophic lateral sclerosis. Ann Clin Transl Neurol. 2018 Dec; 5(12):1522-1533.
PMID:
30564619
; PMCID:
PMC6292193
.
Citations:
7
Fields:
Neu
Neurology
Bhattacharyya S
,
Macklin EA
,
Schwarzschild MA
. Cardiovascular Safety of Febuxostat. N Engl J Med. 2018 10 18; 379(16):1582.
PMID:
30338966
.
Citations:
Fields:
Med
Medicine (General)
Translation:
Humans
Palacios N, Hughes KC, Cereda E,
Schwarzschild MA
,
Ascherio A
. Appendectomy and risk of Parkinson's disease in two large prospective cohorts of men and women. Mov Disord. 2018 09; 33(9):1492-1496.
PMID:
30218460
.
Citations:
14
Fields:
Neu
Neurology
Translation:
Humans
Iwaki H, Hughes KC, Gao X,
Schwarzschild MA
,
Ascherio A
. The association between restless legs syndrome and premotor symptoms of Parkinson's disease. J Neurol Sci. 2018 11 15; 394:41-44.
PMID:
30212740
.
Citations:
5
Fields:
Neu
Neurology
Translation:
Humans
Hughes KC, Gao X, Baker JM,
Stephen C
, Kim IY,
Valeri L
,
Schwarzschild MA
,
Ascherio A
. Non-motor features of Parkinson's disease in a nested case-control study of US men. J Neurol Neurosurg Psychiatry. 2018 12; 89(12):1288-1295.
PMID:
30076266
.
Citations:
8
Fields:
Neu
Neurology
Neu
Neurosurgery
Psy
Psychiatry
Translation:
Humans
Bakshi R
, Xu Y, Mueller KA, Chen X, Granucci E,
Paganoni S
,
Sadri-Vakili G
,
Schwarzschild MA
. Urate mitigates oxidative stress and motor neuron toxicity of astrocytes derived from ALS-linked SOD1G93A mutant mice. Mol Cell Neurosci. 2018 10; 92:12-16.
PMID:
29928993
.
Citations:
10
Fields:
Cel
Cell Biology
Mol
Molecular Biology
Neu
Neurology
Translation:
Animals
Cells
Hughes KC, Gao X, O'Reilly EJ, Kim IY,
Wang M
,
Weisskopf MG
,
Schwarzschild MA
,
Ascherio A
. Genetic variants related to urate and risk of Parkinson's disease. Parkinsonism Relat Disord. 2018 08; 53:4-9.
PMID:
29789205
.
Citations:
2
Fields:
Neu
Neurology
Translation:
Humans
Kim IY, O'Reilly ÉJ, Hughes KC, Gao X,
Schwarzschild MA
,
Hannan MT
,
Betensky RA
,
Ascherio A
. Integration of risk factors for Parkinson disease in 2 large longitudinal cohorts. Neurology. 2018 05 08; 90(19):e1646-e1653.
PMID:
29643081
.
Citations:
8
Fields:
Neu
Neurology
Translation:
Humans
Cai W, Feng D,
Schwarzschild MA
, McLean PJ, Chen X. Bimolecular Fluorescence Complementation of Alpha-synuclein Demonstrates its Oligomerization with Dopaminergic Phenotype in Mice. EBioMedicine. 2018 Mar; 29:13-22.
PMID:
29433982
.
Citations:
10
Fields:
Gen
Genetics
Med
Medicine (General)
Translation:
Humans
Animals
Cells
Kim IY, O'Reilly ÉJ, Hughes KC, Gao X,
Schwarzschild MA
, McCullough ML,
Hannan MT
,
Betensky RA
,
Ascherio A
. Interaction between caffeine and polymorphisms of glutamate ionotropic receptor NMDA type subunit 2A (GRIN2A) and cytochrome P450 1A2 (CYP1A2) on Parkinson's disease risk. Mov Disord. 2018 03; 33(3):414-420.
PMID:
29318639
; PMCID:
PMC5839986
.
Citations:
6
Fields:
Neu
Neurology
Translation:
Humans
O'Reilly ÉJ,
Bjornevik K
,
Schwarzschild MA
, McCullough ML, Kolonel LN, Le Marchand L,
Manson JE
,
Ascherio A
. Pre-diagnostic plasma urate and the risk of amyotrophic lateral sclerosis. Amyotroph Lateral Scler Frontotemporal Degener. 2018 05; 19(3-4):194-200.
PMID:
29277115
; PMCID:
PMC6423442
.
Citations:
7
Fields:
Neu
Neurology
Translation:
Humans
Ascherio A
,
Schwarzschild MA
. Dietary antioxidants and Parkinson's disease. Mov Disord. 2017 11; 32(11):1501-1503.
PMID:
28976040
.
Citations:
2
Fields:
Neu
Neurology
Translation:
Humans
Palacios N, Fitzgerald KC, Hart JE,
Weisskopf M
,
Schwarzschild MA
,
Ascherio A
,
Laden F
. Air Pollution and Risk of Parkinson's Disease in a Large Prospective Study of Men. Environ Health Perspect. 2017 08 18; 125(8):087011.
PMID:
28886605
; PMCID:
PMC5783632
.
Citations:
10
Fields:
Env
Environmental Health
Translation:
Humans
PH
Public Health
Crotty GF
,
Ascherio A<