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profileRobert R Edwards, Ph.D.

TitleAssociate Professor of Anaesthesia
InstitutionBrigham and Women's Hospital
DepartmentAnaesthesia
AddressBrigham and Women's Hospital
Pain Management Ctr
850 Boylston St
Chestnut Hill MA 02467
Phone617/732-9486
Fax617/732-9050
vCardDownload vCard (login for email)

Collapse Research 
Collapse research activities and funding
The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
Most Recent  |  List All
R21DA041020     (EDWARDS, ROBERT R)Aug 1, 2016 - Jul 31, 2018
NIH/NIDA
Opioid-induced change in pain sensitivity and modulation: Links to opioid misuse
Role: Principal Investigator
R01AR064367     (EDWARDS, ROBERT R)May 12, 2014 - Jul 31, 2019
NIH/NIAMS
Brain Mechanisms Underlying CBT-Related Reductions in Fibromyalgia
Role: Principal Investigator
R21CA171316     (BASARIA, SHEHZAD)Apr 1, 2013 - Mar 31, 2015
NIH/NCI
Hypogonadism and Pain Perception in Androgen-Deprived Men with Prostate Cancer
Role: Co-Principal Investigator
R13NS083322     (EDWARDS, ROBERT R)Apr 1, 2013 - Mar 31, 2014
NIH/NINDS
Young Investigator Travel Support for 2013 APS Annual Scientific Meeting
Role: Principal Investigator
R21AR057920     (EDWARDS, ROBERT R)Aug 1, 2010 - Jul 31, 2013
NIH/NIAMS
Catastrophizing and Cytokine Responses to Acute Pain in the Rheumatic Diseases
Role: Principal Investigator

Collapse Bibliographic 
Collapse selected publications
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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  1. Abrecht CR, Cornelius M, Wu A, Jamison RN, Janfaza D, Urman RD, Campbell C, Smith M, Haythornthwaite J, Edwards RR, Schreiber KL. Prediction of Pain and Opioid Utilization in the Perioperative Period in Patients Undergoing Primary Knee Arthroplasty: Psychophysical and Psychosocial Factors. Pain Med. 2018 Mar 07. PMID: 29522115.
    View in: PubMed
  2. Mariano TY, Urman RD, Hutchison CA, Jamison RN, Edwards RR. Cognitive Behavioral Therapy (CBT) for Subacute Low Back Pain: a Systematic Review. Curr Pain Headache Rep. 2018 Feb 23; 22(3):15. PMID: 29476270.
    View in: PubMed
  3. Lee YC, Bingham CO, Edwards RR, Marder W, Phillips K, Bolster MB, Clauw DJ, Moreland LW, Lu B, Wohlfahrt A, Zhang Z, Neogi T. Association Between Pain Sensitization and Disease Activity in Patients With Rheumatoid Arthritis: A Cross-Sectional Study. Arthritis Care Res (Hoboken). 2018 Feb; 70(2):197-204. PMID: 28437846.
    View in: PubMed
  4. Meints SM, Edwards RR. Evaluating psychosocial contributions to chronic pain outcomes. Prog Neuropsychopharmacol Biol Psychiatry. 2018 Jan 30. PMID: 29408484.
    View in: PubMed
  5. Gollub RL, Kirsch I, Maleki N, Wasan AD, Edwards RR, Tu Y, Kaptchuk TJ, Kong J. A Functional Neuroimaging Study of Expectancy Effects on Pain Response in Patients With Knee Osteoarthritis. J Pain. 2018 Jan 08. PMID: 29325883.
    View in: PubMed
  6. Chai PR, Carreiro S, Innes BJ, Chapman B, Schreiber KL, Edwards RR, Carrico AW, Boyer EW. Oxycodone Ingestion Patterns in Acute Fracture Pain With Digital Pills. Anesth Analg. 2017 12; 125(6):2105-2112. PMID: 29189367.
    View in: PubMed
  7. Gagliano-Jucá T, Travison TG, Nguyen PL, Kantoff PW, Taplin ME, Kibel AS, Manley R, Hally K, Bearup R, Beleva YM, Huang G, Edwards RR, Basaria S. Effects of Androgen Deprivation Therapy on Pain Perception, Quality of Life, and Depression in Men With Prostate Cancer. J Pain Symptom Manage. 2018 Feb; 55(2):307-317.e1. PMID: 28941963.
    View in: PubMed
  8. Jamison RN, Mei A, Edwards RR, Ross EL. Efficacy of Vibrating Gloves for Chronic Hand Pain due to Osteoarthritis. Pain Med. 2017 Sep 14. PMID: 29025096.
    View in: PubMed
  9. Tompkins DA, Huhn AS, Johnson PS, Smith MT, Strain EC, Edwards RR, Johnson MW. To take or not to take: the association between perceived addiction risk, expected analgesic response and likelihood of trying novel pain relievers in self-identified chronic pain patients. Addiction. 2018 Jan; 113(1):67-79. PMID: 28645137.
    View in: PubMed
  10. Garcia RG, Lin RL, Lee J, Kim J, Barbieri R, Sclocco R, Wasan AD, Edwards RR, Rosen BR, Hadjikhani N, Napadow V. Modulation of brainstem activity and connectivity by respiratory-gated auricular vagal afferent nerve stimulation in migraine patients. Pain. 2017 Aug; 158(8):1461-1472. PMID: 28541256.
    View in: PubMed
  11. Jamison RN, Jurcik DC, Edwards RR, Huang CC, Ross EL. A Pilot Comparison of a Smartphone App With or Without 2-Way Messaging Among Chronic Pain Patients: Who Benefits From a Pain App? Clin J Pain. 2017 Aug; 33(8):676-686. PMID: 27898460.
    View in: PubMed
  12. Sundararaman LV, Edwards RR, Ross EL, Jamison RN. Integration of Mobile Health Technology in the Treatment of Chronic Pain: A Critical Review. Reg Anesth Pain Med. 2017 Jul/Aug; 42(4):488-498. PMID: 28570436.
    View in: PubMed
  13. Berna C, Kirsch I, Zion SR, Lee YC, Jensen KB, Sadler P, Kaptchuk TJ, Edwards RR. Side effects can enhance treatment response through expectancy effects: an experimental analgesic randomized controlled trial. Pain. 2017 Jun; 158(6):1014-1020. PMID: 28178072.
    View in: PubMed
  14. Huang G, Travison TG, Edwards RR, Basaria S. Effects of Testosterone Replacement on Pain Catastrophizing and Sleep Quality in Men with Opioid-Induced Androgen Deficiency. Pain Med. 2017 Jun 01; 18(6):1070-1076. PMID: 27550959.
    View in: PubMed
  15. Riley JL, Cruz-Almeida Y, Dasilva Ribeiro MC, Simon CB, Eckert NR, Aguirre M, Sorenson HL, Tighe PJ, Edwards RR, Wallet SM. Age Differences in the Time Course and Magnitude of Changes in Circulating Neuropeptides After Pain Evocation in Humans. J Pain. 2017 Sep; 18(9):1078-1086. PMID: 28461253.
    View in: PubMed
  16. Zghoul N, Ross EL, Edwards RR, Ahmed A, Jamison RN. Prevalence of chronic pain with neuropathic characteristics: a randomized telephone survey among medical center patients in Kuwait. J Pain Res. 2017; 10:679-687. PMID: 28435312.
    View in: PubMed
  17. Schreiber KL, Loggia ML, Kim J, Cahalan CM, Napadow V, Edwards RR. Painful After-Sensations in Fibromyalgia are Linked to Catastrophizing and Differences in Brain Response in the Medial Temporal Lobe. J Pain. 2017 Jul; 18(7):855-867. PMID: 28300650.
    View in: PubMed
  18. Jamison RN, Dorado K, Mei A, Edwards RR, Martel MO. Influence of opioid-related side effects on disability, mood, and opioid misuse risk among patients with chronic pain in primary care. Pain Rep. 2017 Mar; 2(2):e589. PMID: 29392205.
    View in: PubMed
  19. Lazaridou A, Kim J, Cahalan CM, Loggia ML, Franceschelli O, Berna C, Schur P, Napadow V, Edwards RR. Effects of Cognitive-Behavioral Therapy (CBT) on Brain Connectivity Supporting Catastrophizing in Fibromyalgia. Clin J Pain. 2017 Mar; 33(3):215-221. PMID: 27518491.
    View in: PubMed
  20. Smith SM, Dworkin RH, Turk DC, Baron R, Polydefkis M, Tracey I, Borsook D, Edwards RR, Harris RE, Wager TD, Arendt-Nielsen L, Burke LB, Carr DB, Chappell A, Farrar JT, Freeman R, Gilron I, Goli V, Haeussler J, Jensen T, Katz NP, Kent J, Kopecky EA, Lee DA, Maixner W, Markman JD, McArthur JC, McDermott MP, Parvathenani L, Raja SN, Rappaport BA, Rice ASC, Rowbotham MC, Tobias JK, Wasan AD, Witter J. The Potential Role of Sensory Testing, Skin Biopsy, and Functional Brain Imaging as Biomarkers in Chronic Pain Clinical Trials: IMMPACT Considerations. J Pain. 2017 Jul; 18(7):757-777. PMID: 28254585.
    View in: PubMed
  21. Dworkin RH, Edwards RR. Phenotypes and treatment response: it's difficult to make predictions, especially about the future. Pain. 2017 02; 158(2):187-189. PMID: 28092645.
    View in: PubMed
  22. Mathur VA, Kiley KB, Haywood C, Bediako SM, Lanzkron S, Carroll CP, Buenaver LF, Pejsa M, Edwards RR, Haythornthwaite JA, Campbell CM. Multiple Levels of Suffering: Discrimination in Health-Care Settings is Associated With Enhanced Laboratory Pain Sensitivity in Sickle Cell Disease. Clin J Pain. 2016 Dec; 32(12):1076-1085. PMID: 26889615.
    View in: PubMed
  23. Chen X, Spaeth RB, Freeman SG, Scarborough DM, Hashmi JA, Wey HY, Egorova N, Vangel M, Mao J, Wasan AD, Edwards RR, Gollub RL, Kong J. The Modulation Effect of Longitudinal Acupuncture on Resting State Functional Connectivity in Knee Osteoarthritis Patients. Mol Pain. 2015 01; 11. PMID: 27655921.
    View in: PubMed
  24. Edwards RR, Dworkin RH, Turk DC, Angst MS, Dionne R, Freeman R, Hansson P, Haroutounian S, Arendt-Nielsen L, Attal N, Baron R, Brell J, Bujanover S, Burke LB, Carr D, Chappell AS, Cowan P, Etropolski M, Fillingim RB, Gewandter JS, Katz NP, Kopecky EA, Markman JD, Nomikos G, Porter L, Rappaport BA, Rice AS, Scavone JM, Scholz J, Simon LS, Smith SM, Tobias J, Tockarshewsky T, Veasley C, Versavel M, Wasan AD, Wen W, Yarnitsky D. Patient phenotyping in clinical trials of chronic pain treatments: IMMPACT recommendations. Pain. 2016 Sep; 157(9):1851-71. PMID: 27152687.
    View in: PubMed
  25. Fillingim RB, Loeser JD, Baron R, Edwards RR. Assessment of Chronic Pain: Domains, Methods, and Mechanisms. J Pain. 2016 Sep; 17(9 Suppl):T10-20. PMID: 27586827.
    View in: PubMed
  26. Edwards RR, Dworkin RH, Sullivan MD, Turk DC, Wasan AD. The Role of Psychosocial Processes in the Development and Maintenance of Chronic Pain. J Pain. 2016 Sep; 17(9 Suppl):T70-92. PMID: 27586832; PMCID: PMC5012303 [Available on 09/01/17].
    View in: PubMed, PubMed Central
  27. Mathur VA, Kiley KB, Carroll CP, Edwards RR, Lanzkron S, Haythornthwaite JA, Campbell CM. Disease-Related, Nondisease-Related, and Situational Catastrophizing in Sickle Cell Disease and Its Relationship With Pain. J Pain. 2016 11; 17(11):1227-1236. PMID: 27555427.
    View in: PubMed
  28. Lee J, Lin RL, Garcia RG, Kim J, Kim H, Loggia ML, Mawla I, Wasan AD, Edwards RR, Rosen BR, Hadjikhani N, Napadow V. Reduced insula habituation associated with amplification of trigeminal brainstem input in migraine. Cephalalgia. 2017 Oct; 37(11):1026-1038. PMID: 27521844.
    View in: PubMed
  29. Tompkins DA, Johnson PS, Smith MT, Strain EC, Edwards RR, Johnson MW. Temporal preference in individuals reporting chronic pain: discounting of delayed pain-related and monetary outcomes. Pain. 2016 08; 157(8):1724-32. PMID: 27075431.
    View in: PubMed
  30. Edwards RR, Dolman AJ, Martel MO, Finan PH, Lazaridou A, Cornelius M, Wasan AD. Variability in conditioned pain modulation predicts response to NSAID treatment in patients with knee osteoarthritis. BMC Musculoskelet Disord. 2016 07 13; 17:284. PMID: 27412526; PMCID: PMC4944243.
    View in: PubMed, PubMed Central
  31. Tsui JI, Lira MC, Cheng DM, Winter MR, Alford DP, Liebschutz JM, Edwards RR, Samet JH. Chronic pain, craving, and illicit opioid use among patients receiving opioid agonist therapy. Drug Alcohol Depend. 2016 09 01; 166:26-31. PMID: 27422763; PMCID: PMC4983520 [Available on 09/01/17].
    View in: PubMed, PubMed Central
  32. Huang G, Travison T, Maggio M, Edwards RR, Basaria S. Effects of testosterone replacement on metabolic and inflammatory markers in men with opioid-induced androgen deficiency. Clin Endocrinol (Oxf). 2016 Aug; 85(2):232-8. PMID: 26928845.
    View in: PubMed
  33. McHugh RK, Weiss RD, Cornelius M, Martel MO, Jamison RN, Edwards RR. Distress Intolerance and Prescription Opioid Misuse Among Patients With Chronic Pain. J Pain. 2016 07; 17(7):806-14. PMID: 27058161; PMCID: PMC4925301 [Available on 07/01/17].
    View in: PubMed, PubMed Central
  34. Campbell CM, Carroll CP, Kiley K, Han D, Haywood C, Lanzkron S, Swedberg L, Edwards RR, Page GG, Haythornthwaite JA. Quantitative sensory testing and pain-evoked cytokine reactivity: comparison of patients with sickle cell disease to healthy matched controls. Pain. 2016 Apr; 157(4):949-56. PMID: 26713424; PMCID: PMC4932897 [Available on 04/01/17].
    View in: PubMed, PubMed Central
  35. Basaria S, Edwards RR, Travison TG. Reply. Pain. 2016 Apr; 157(4):990-1. PMID: 26982516.
    View in: PubMed
  36. Wideman TH, Edwards RR, Finan PH, Haythornthwaite JA, Smith MT. Comparing the Predictive Value of Task Performance and Task-Specific Sensitivity During Physical Function Testing Among People With Knee Osteoarthritis. J Orthop Sports Phys Ther. 2016 May; 46(5):346-56. PMID: 26999411.
    View in: PubMed
  37. Martel MO, Finan PH, McHugh RK, Issa M, Edwards RR, Jamison RN, Wasan AD. Day-to-day pain symptoms are only weakly associated with opioid craving among patients with chronic pain prescribed opioid therapy. Drug Alcohol Depend. 2016 May 01; 162:130-6. PMID: 27021805; PMCID: PMC4833606 [Available on 05/01/17].
    View in: PubMed, PubMed Central
  38. Edwards RR, Dolman AJ, Michna E, Katz JN, Nedeljkovic SS, Janfaza D, Isaac Z, Martel MO, Jamison RN, Wasan AD. Changes in Pain Sensitivity and Pain Modulation During Oral Opioid Treatment: The Impact of Negative Affect. Pain Med. 2016 Oct; 17(10):1882-1891. PMID: 26933094.
    View in: PubMed
  39. Martel MO, Olesen AE, Jørgensen D, Nielsen LM, Brock C, Edwards RR, Drewes AM. Does catastrophic thinking enhance oesophageal pain sensitivity? An experimental investigation. Eur J Pain. 2016 Sep; 20(8):1214-22. PMID: 26919233.
    View in: PubMed
  40. Campbell CM, Moscou-Jackson G, Carroll CP, Kiley K, Haywood C, Lanzkron S, Hand M, Edwards RR, Haythornthwaite JA. An Evaluation of Central Sensitization in Patients With Sickle Cell Disease. J Pain. 2016 05; 17(5):617-27. PMID: 26892240; PMCID: PMC4851873 [Available on 05/01/17].
    View in: PubMed, PubMed Central
  41. Lazaridou A, Edwards RR. Getting personal: the role of individual patient preferences and characteristics in shaping pain treatment outcomes. Pain. 2016 Jan; 157(1):1-2. PMID: 26447708.
    View in: PubMed
  42. Jamison RN, Martel MO, Huang CC, Jurcik D, Edwards RR. Efficacy of the Opioid Compliance Checklist to Monitor Chronic Pain Patients Receiving Opioid Therapy in Primary Care. J Pain. 2016 Apr; 17(4):414-23. PMID: 26705974.
    View in: PubMed
  43. Lee YC, Massarotti E, Edwards RR, Lu B, Liu C, Lo Y, Wohlfahrt A, Kim ND, Clauw DJ, Solomon DH. Effect of Milnacipran on Pain in Patients with Rheumatoid Arthritis with Widespread Pain: A Randomized Blinded Crossover Trial. J Rheumatol. 2016 Jan; 43(1):38-45. PMID: 26628607; PMCID: PMC4698221.
    View in: PubMed, PubMed Central
  44. Chen X, Spaeth RB, Freeman SG, Scarborough DM, Hashmi JA, Wey HY, Egorova N, Vangel M, Mao J, Wasan AD, Edwards RR, Gollub RL, Kong J. The modulation effect of longitudinal acupuncture on resting state functional connectivity in knee osteoarthritis patients. Mol Pain. 2015 Oct 29; 11:67. PMID: 26511911; PMCID: PMC4625557.
    View in: PubMed, PubMed Central
  45. Wasan AD, Michna E, Edwards RR, Katz JN, Nedeljkovic SS, Dolman AJ, Janfaza D, Isaac Z, Jamison RN. Psychiatric Comorbidity Is Associated Prospectively with Diminished Opioid Analgesia and Increased Opioid Misuse in Patients with Chronic Low Back Pain. Anesthesiology. 2015 Oct; 123(4):861-72. PMID: 26375824; PMCID: PMC4573512 [Available on 10/01/16].
    View in: PubMed, PubMed Central
  46. Campbell CM, Buenaver LF, Finan P, Bounds SC, Redding M, McCauley L, Robinson M, Edwards RR, Smith MT. Sleep, Pain Catastrophizing, and Central Sensitization in Knee Osteoarthritis Patients With and Without Insomnia. Arthritis Care Res (Hoboken). 2015 Oct; 67(10):1387-96. PMID: 26041510; PMCID: PMC4580506 [Available on 10/01/16].
    View in: PubMed, PubMed Central
  47. Deeny MC, Al Hamdan E, Ross EL, Edwards RR, Huang CC, Jamison RN. Chronic Pain, Comorbid Medical Conditions, and Associated Risk Factors in Kuwait: Gender and Nationality Differences. Pain Med. 2015 Nov; 16(11):2204-11. PMID: 26118589.
    View in: PubMed
  48. Martel MO, Finan PH, Dolman AJ, Subramanian S, Edwards RR, Wasan AD, Jamison RN. Self-reports of medication side effects and pain-related activity interference in patients with chronic pain: a longitudinal cohort study. Pain. 2015 Jun; 156(6):1092-100. PMID: 25782367; PMCID: PMC4431924.
    View in: PubMed, PubMed Central
  49. Tsui JI, Lira MC, Cheng DM, Winter MR, Alford DP, Liebschutz JM, Mao J, Edwards RR, Samet JH. Hepatitis C virus infection and pain sensitivity in patients on methadone or buprenorphine maintenance therapy for opioid use disorders. Drug Alcohol Depend. 2015 Aug 01; 153:286-92. PMID: 26048638; PMCID: PMC4509826.
    View in: PubMed, PubMed Central
  50. Kim J, Loggia ML, Cahalan CM, Harris RE, Beissner F, Garcia RG, Kim H, Wasan AD, Edwards RR, Napadow V. The somatosensory link in fibromyalgia: functional connectivity of the primary somatosensory cortex is altered by sustained pain and is associated with clinical/autonomic dysfunction. Arthritis Rheumatol. 2015 May; 67(5):1395-1405. PMID: 25622796; PMCID: PMC4414820.
    View in: PubMed, PubMed Central
  51. Loggia ML, Berna C, Kim J, Cahalan CM, Martel MO, Gollub RL, Wasan AD, Napadow V, Edwards RR. The lateral prefrontal cortex mediates the hyperalgesic effects of negative cognitions in chronic pain patients. J Pain. 2015 Aug; 16(8):692-9. PMID: 25937162.
    View in: PubMed
  52. Kim H, Kim J, Loggia ML, Cahalan C, Garcia RG, Vangel MG, Wasan AD, Edwards RR, Napadow V. Fibromyalgia is characterized by altered frontal and cerebellar structural covariance brain networks. Neuroimage Clin. 2015; 7:667-77. PMID: 25844321; PMCID: PMC4379388.
    View in: PubMed, PubMed Central
  53. Katz NP, Paillard FC, Edwards RR. Review of the performance of quantitative sensory testing methods to detect hyperalgesia in chronic pain patients on long-term opioids. Anesthesiology. 2015 Mar; 122(3):677-85. PMID: 25437498.
    View in: PubMed
  54. Smith SM, Paillard F, McKeown A, Burke LB, Edwards RR, Katz NP, Papadopoulos EJ, Rappaport BA, Slagle A, Strain EC, Wasan AD, Turk DC, Dworkin RH. Instruments to Identify Prescription Medication Misuse, Abuse, and Related Events in Clinical Trials: An ACTTION Systematic Review. J Pain. 2015 May; 16(5):389-411. PMID: 25660826.
    View in: PubMed
  55. Basaria S, Travison TG, Alford D, Knapp PE, Teeter K, Cahalan C, Eder R, Lakshman K, Bachman E, Mensing G, Martel MO, Le D, Stroh H, Bhasin S, Wasan AD, Edwards RR. Effects of testosterone replacement in men with opioid-induced androgen deficiency: a randomized controlled trial. Pain. 2015 Feb; 156(2):280-8. PMID: 25599449.
    View in: PubMed
  56. Loggia ML, Chonde DB, Akeju O, Arabasz G, Catana C, Edwards RR, Hill E, Hsu S, Izquierdo-Garcia D, Ji RR, Riley M, Wasan AD, Zürcher NR, Albrecht DS, Vangel MG, Rosen BR, Napadow V, Hooker JM. Evidence for brain glial activation in chronic pain patients. Brain. 2015 Mar; 138(Pt 3):604-15. PMID: 25582579.
    View in: PubMed
  57. Schreiber KL, Campbell C, Martel MO, Greenbaum S, Wasan AD, Borsook D, Jamison RN, Edwards RR. Distraction analgesia in chronic pain patients: the impact of catastrophizing. Anesthesiology. 2014 Dec; 121(6):1292-301. PMID: 25264596.
    View in: PubMed
  58. Dolman AJ, Loggia ML, Edwards RR, Gollub RL, Kong J, Napadow V, Wasan AD. Phenotype matters: the absence of a positive association between cortical thinning and chronic low back pain when controlling for salient clinical variables. Clin J Pain. 2014 Oct; 30(10):839-45. PMID: 24135900; PMCID: PMC4103969.
    View in: PubMed, PubMed Central
  59. Hsieh C, Kong J, Kirsch I, Edwards RR, Jensen KB, Kaptchuk TJ, Gollub RL. Well-loved music robustly relieves pain: a randomized, controlled trial. PLoS One. 2014; 9(9):e107390. PMID: 25211164; PMCID: PMC4161415.
    View in: PubMed, PubMed Central
  60. Jamison RN, Martel MO, Edwards RR, Qian J, Sheehan KA, Ross EL. Validation of a brief Opioid Compliance Checklist for patients with chronic pain. J Pain. 2014 Nov; 15(11):1092-101. PMID: 25092233.
    View in: PubMed
  61. Issa MA, Narang S, Jamison RN, Michna E, Edwards RR, Penetar DM, Wasan AD. The subjective psychoactive effects of oral dronabinol studied in a randomized, controlled crossover clinical trial for pain. Clin J Pain. 2014 Jun; 30(6):472-8. PMID: 24281276; PMCID: PMC4013220.
    View in: PubMed, PubMed Central
  62. Loggia ML, Edwards RR, Harris RE, Napadow V. Reply: To PMID 24449585. Arthritis Rheumatol. 2014 Jun; 66(6):1684-5. PMID: 24515749; PMCID: PMC4195441.
    View in: PubMed, PubMed Central
  63. Martel MO, Jamison RN, Wasan AD, Edwards RR. The association between catastrophizing and craving in patients with chronic pain prescribed opioid therapy: a preliminary analysis. Pain Med. 2014 Oct; 15(10):1757-64. PMID: 24612286; PMCID: PMC4160420.
    View in: PubMed, PubMed Central
  64. Fillingim RB, Bruehl S, Dworkin RH, Dworkin SF, Loeser JD, Turk DC, Widerstrom-Noga E, Arnold L, Bennett R, Edwards RR, Freeman R, Gewandter J, Hertz S, Hochberg M, Krane E, Mantyh PW, Markman J, Neogi T, Ohrbach R, Paice JA, Porreca F, Rappaport BA, Smith SM, Smith TJ, Sullivan MD, Verne GN, Wasan AD, Wesselmann U. The ACTTION-American Pain Society Pain Taxonomy (AAPT): an evidence-based and multidimensional approach to classifying chronic pain conditions. J Pain. 2014 Mar; 15(3):241-9. PMID: 24581634; PMCID: PMC4454364.
    View in: PubMed, PubMed Central
  65. Schreiber KL, Kehlet H, Belfer I, Edwards RR. Predicting, preventing and managing persistent pain after breast cancer surgery: the importance of psychosocial factors. Pain Manag. 2014; 4(6):445-59. PMID: 25494696.
    View in: PubMed
  66. Loggia ML, Berna C, Kim J, Cahalan CM, Gollub RL, Wasan AD, Harris RE, Edwards RR, Napadow V. Disrupted brain circuitry for pain-related reward/punishment in fibromyalgia. Arthritis Rheumatol. 2014 Jan; 66(1):203-12. PMID: 24449585; PMCID: PMC4516215.
    View in: PubMed, PubMed Central
  67. Wideman TH, Finan PH, Edwards RR, Quartana PJ, Buenaver LF, Haythornthwaite JA, Smith MT. Increased sensitivity to physical activity among individuals with knee osteoarthritis: relation to pain outcomes, psychological factors, and responses to quantitative sensory testing. Pain. 2014 Apr; 155(4):703-11. PMID: 24378879.
    View in: PubMed
  68. Martel MO, Dolman AJ, Edwards RR, Jamison RN, Wasan AD. The association between negative affect and prescription opioid misuse in patients with chronic pain: the mediating role of opioid craving. J Pain. 2014 Jan; 15(1):90-100. PMID: 24295876; PMCID: PMC3877217.
    View in: PubMed, PubMed Central
  69. Campbell CM, Bounds SC, Kuwabara H, Edwards RR, Campbell JN, Haythornthwaite JA, Smith MT. individual variation in sleep quality and duration is related to cerebral mu opioid receptor binding potential during tonic laboratory pain in healthy subjects. Pain Med. 2013 Dec; 14(12):1882-92. PMID: 24102962; PMCID: PMC4104524.
    View in: PubMed, PubMed Central
  70. Martel MO, Wasan AD, Edwards RR. Sex differences in the stability of conditioned pain modulation (CPM) among patients with chronic pain. Pain Med. 2013 Nov; 14(11):1757-68. PMID: 23924369; PMCID: PMC3833959.
    View in: PubMed, PubMed Central
  71. Belfer I, Schreiber KL, Shaffer JR, Shnol H, Blaney K, Morando A, Englert D, Greco C, Brufsky A, Ahrendt G, Kehlet H, Edwards RR, Bovbjerg DH. Persistent postmastectomy pain in breast cancer survivors: analysis of clinical, demographic, and psychosocial factors. J Pain. 2013 Oct; 14(10):1185-95. PMID: 23890847.
    View in: PubMed
  72. Spaeth RB, Camhi S, Hashmi JA, Vangel M, Wasan AD, Edwards RR, Gollub RL, Kong J. A longitudinal study of the reliability of acupuncture deqi sensations in knee osteoarthritis. Evid Based Complement Alternat Med. 2013; 2013:204259. PMID: 23935656; PMCID: PMC3713327.
    View in: PubMed, PubMed Central
  73. Smith SM, Dart RC, Katz NP, Paillard F, Adams EH, Comer SD, Degroot A, Edwards RR, Haddox JD, Jaffe JH, Jones CM, Kleber HD, Kopecky EA, Markman JD, Montoya ID, O'Brien C, Roland CL, Stanton M, Strain EC, Vorsanger G, Wasan AD, Weiss RD, Turk DC, Dworkin RH. Classification and definition of misuse, abuse, and related events in clinical trials: ACTTION systematic review and recommendations. Pain. 2013 Nov; 154(11):2287-96. PMID: 23792283.
    View in: PubMed
  74. Wideman TH, Asmundson GG, Smeets RJ, Zautra AJ, Simmonds MJ, Sullivan MJ, Haythornthwaite JA, Edwards RR. Rethinking the fear avoidance model: toward a multidimensional framework of pain-related disability. Pain. 2013 Nov; 154(11):2262-5. PMID: 23748115; PMCID: PMC4078976.
    View in: PubMed, PubMed Central
  75. Backonja MM, Attal N, Baron R, Bouhassira D, Drangholt M, Dyck PJ, Edwards RR, Freeman R, Gracely R, Haanpaa MH, Hansson P, Hatem SM, Krumova EK, Jensen TS, Maier C, Mick G, Rice AS, Rolke R, Treede RD, Serra J, Toelle T, Tugnoli V, Walk D, Walalce MS, Ware M, Yarnitsky D, Ziegler D. Value of quantitative sensory testing in neurological and pain disorders: NeuPSIG consensus. Pain. 2013 Sep; 154(9):1807-19. PMID: 23742795.
    View in: PubMed
  76. Martel MO, Wasan AD, Jamison RN, Edwards RR. Catastrophic thinking and increased risk for prescription opioid misuse in patients with chronic pain. Drug Alcohol Depend. 2013 Sep 01; 132(1-2):335-41. PMID: 23618767; PMCID: PMC3745790.
    View in: PubMed, PubMed Central
  77. Belfer I, Segall SK, Lariviere WR, Smith SB, Dai F, Slade GD, Rashid NU, Mogil JS, Campbell CM, Edwards RR, Liu Q, Bair E, Maixner W, Diatchenko L. Pain modality- and sex-specific effects of COMT genetic functional variants. Pain. 2013 Aug; 154(8):1368-76. PMID: 23701723; PMCID: PMC3700530.
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  81. Lee YC, Lu B, Edwards RR, Wasan AD, Nassikas NJ, Clauw DJ, Solomon DH, Karlson EW. The role of sleep problems in central pain processing in rheumatoid arthritis. Arthritis Rheum. 2013 Jan; 65(1):59-68. PMID: 23124650; PMCID: PMC3535519.
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  82. Schreiber KL, Martel MO, Shnol H, Shaffer JR, Greco C, Viray N, Taylor LN, McLaughlin M, Brufsky A, Ahrendt G, Bovbjerg D, Edwards RR, Belfer I. Persistent pain in postmastectomy patients: comparison of psychophysical, medical, surgical, and psychosocial characteristics between patients with and without pain. Pain. 2013 May; 154(5):660-8. PMID: 23290256; PMCID: PMC3863788.
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  84. Campbell CM, McCauley L, Bounds SC, Mathur VA, Conn L, Simango M, Edwards RR, Fontaine KR. Changes in pain catastrophizing predict later changes in fibromyalgia clinical and experimental pain report: cross-lagged panel analyses of dispositional and situational catastrophizing. Arthritis Res Ther. 2012 Oct 25; 14(5):R231. PMID: 23098173; PMCID: PMC3580543.
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  85. Jamison RN, Edwards RR. Risk factor assessment for problematic use of opioids for chronic pain. Clin Neuropsychol. 2013; 27(1):60-80. PMID: 22935011.
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  87. Jamison RN, Edwards RR, Liu X, Ross EL, Michna E, Warnick M, Wasan AD. Relationship of negative affect and outcome of an opioid therapy trial among low back pain patients. Pain Pract. 2013 Mar; 13(3):173-81. PMID: 22681407; PMCID: PMC3869183.
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  88. Napadow V, Edwards RR, Cahalan CM, Mensing G, Greenbaum S, Valovska A, Li A, Kim J, Maeda Y, Park K, Wasan AD. Evoked pain analgesia in chronic pelvic pain patients using respiratory-gated auricular vagal afferent nerve stimulation. Pain Med. 2012 Jun; 13(6):777-89. PMID: 22568773; PMCID: PMC3376238.
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  89. Goodin BR, Quinn NB, King CD, Page GG, Haythornthwaite JA, Edwards RR, Stapleton LM, McGuire L. Enhanced cortisol increase upon awakening is associated with greater pain ratings but not salivary cortisol or soluble tumor necrosis factor-a receptor II responses to acute pain. Clin J Pain. 2012 May; 28(4):291-9. PMID: 21904196; PMCID: PMC3237812.
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  90. Campbell CM, Edwards RR. Ethnic differences in pain and pain management. Pain Manag. 2012 May; 2(3):219-230. PMID: 23687518.
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  91. King CD, Goodin B, Kindler LL, Caudle RM, Edwards RR, Gravenstein N, Riley JL, Fillingim RB. Reduction of conditioned pain modulation in humans by naltrexone: an exploratory study of the effects of pain catastrophizing. J Behav Med. 2013 Jun; 36(3):315-27. PMID: 22534819.
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  93. Buenaver LF, Quartana PJ, Grace EG, Sarlani E, Simango M, Edwards RR, Haythornthwaite JA, Smith MT. Evidence for indirect effects of pain catastrophizing on clinical pain among myofascial temporomandibular disorder participants: the mediating role of sleep disturbance. Pain. 2012 Jun; 153(6):1159-66. PMID: 22417656.
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  95. Goodin BR, Quinn NB, Kronfli T, King CD, Page GG, Haythornthwaite JA, Edwards RR, Stapleton LM, McGuire L. Experimental pain ratings and reactivity of cortisol and soluble tumor necrosis factor-a receptor II following a trial of hypnosis: results of a randomized controlled pilot study. Pain Med. 2012 Jan; 13(1):29-44. PMID: 22233394; PMCID: PMC3257832.
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  96. Loggia ML, Jensen K, Gollub RL, Wasan AD, Edwards RR, Kong J. The catechol-O-methyltransferase (COMT) val158met polymorphism affects brain responses to repeated painful stimuli. PLoS One. 2011; 6(11):e27764. PMID: 22132136.
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  99. Cohen LA, Bonito AJ, Eicheldinger C, Manski RJ, Edwards RR, Khanna N. Health literacy impact on patient-provider interactions involving the treatment of dental problems. J Dent Educ. 2011 Sep; 75(9):1218-24. PMID: 21890851; PMCID: PMC3303161.
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  100. Lucey BP, Clifford DB, Creighton J, Edwards RR, McArthur JC, Haythornthwaite J. Relationship of depression and catastrophizing to pain, disability, and medication adherence in patients with HIV-associated sensory neuropathy. AIDS Care. 2011 Aug; 23(8):921-8. PMID: 21500021; PMCID: PMC4418482.
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  102. McCann UD, Edwards RR, Smith MT, Kelley K, Wilson M, Sgambati F, Ricaurte G. Altered pain responses in abstinent (±)3,4-methylenedioxymethamphetamine (MDMA, "ecstasy") users. Psychopharmacology (Berl). 2011 Oct; 217(4):475-84. PMID: 21603895.
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  103. Edwards RR, Quartana PJ, Allen RP, Greenbaum S, Earley CJ, Smith MT. Alterations in pain responses in treated and untreated patients with restless legs syndrome: associations with sleep disruption. Sleep Med. 2011 Jun; 12(6):603-9. PMID: 21570347; PMCID: PMC3433041.
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  104. Edwards RR, Cahalan C, Calahan C, Mensing G, Smith M, Haythornthwaite JA. Pain, catastrophizing, and depression in the rheumatic diseases. Nat Rev Rheumatol. 2011 Apr; 7(4):216-24. PMID: 21283147.
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  105. Cohen LA, Bonito AJ, Eicheldinger C, Manski RJ, Macek MD, Edwards RR, Khanna N. Behavioral and socioeconomic correlates of dental problem experience and patterns of health care-seeking. J Am Dent Assoc. 2011 Feb; 142(2):137-49. PMID: 21282679.
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  106. Cohen LA, Bonito AJ, Eicheldinger C, Manski RJ, Macek MD, Edwards RR, Khanna N. Comparison of patient visits to emergency departments, physician offices, and dental offices for dental problems and injuries. J Public Health Dent. 2011; 71(1):13-22. PMID: 20726944.
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  107. Merry B, Campbell CM, Buenaver LF, McGuire L, Haythornthwaite JA, Doleys DM, Edwards RR. Ethnic Group Differences in the Outcomes of Multidisciplinary Pain Treatment. J Musculoskelet Pain. 2011 Jan; 19(1):24-30. PMID: 21731407.
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  108. Campbell CM, Bounds SC, Simango MB, Witmer KR, Campbell JN, Edwards RR, Haythornthwaite JA, Smith MT. Self-reported sleep duration associated with distraction analgesia, hyperemia, and secondary hyperalgesia in the heat-capsaicin nociceptive model. Eur J Pain. 2011 Jul; 15(6):561-7. PMID: 21194997; PMCID: PMC3076523.
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  109. Fabian LA, McGuire L, Goodin BR, Edwards RR. Ethnicity, catastrophizing, and qualities of the pain experience. Pain Med. 2011 Feb; 12(2):314-21. PMID: 21143756; PMCID: PMC3575103.
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  110. Coughlin JW, Edwards RR, Redgrave GW, Guarda AS. Pain severity in eating disorders predicts longer inpatient hospitalization. Int J Eat Disord. 2010 Dec; 43(8):737-42. PMID: 19842161.
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  111. Lee YC, Lu B, Bathon JM, Haythornthwaite JA, Smith MT, Page GG, Edwards RR. Pain sensitivity and pain reactivity in osteoarthritis. Arthritis Care Res (Hoboken). 2011 Mar; 63(3):320-7. PMID: 20957660; PMCID: PMC3030930.
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  112. Campbell CM, Quartana PJ, Buenaver LF, Haythornthwaite JA, Edwards RR. Changes in situation-specific pain catastrophizing precede changes in pain report during capsaicin pain: a cross-lagged panel analysis among healthy, pain-free participants. J Pain. 2010 Sep; 11(9):876-84. PMID: 20488760.
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  114. Berna C, Leknes S, Holmes EA, Edwards RR, Goodwin GM, Tracey I. Induction of depressed mood disrupts emotion regulation neurocircuitry and enhances pain unpleasantness. Biol Psychiatry. 2010 Jun 01; 67(11):1083-90. PMID: 20303069.
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  115. Yarnitsky D, Arendt-Nielsen L, Bouhassira D, Edwards RR, Fillingim RB, Granot M, Hansson P, Lautenbacher S, Marchand S, Wilder-Smith O. Recommendations on terminology and practice of psychophysical DNIC testing. Eur J Pain. 2010 Apr; 14(4):339. PMID: 20227310.
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  117. Campbell CM, Witmer K, Simango M, Carteret A, Loggia ML, Campbell JN, Haythornthwaite JA, Edwards RR. Catastrophizing delays the analgesic effect of distraction. Pain. 2010 May; 149(2):202-7. PMID: 20188470; PMCID: PMC2860661.
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  118. Cohen LA, Bonito AJ, Eicheldinger C, Manski RJ, Macek MD, Edwards RR, Khanna N. Comparison of patient centeredness of visits to emergency departments, physicians, and dentists for dental problems and injuries. J Am Coll Dent. 2010; 77(4):49-58. PMID: 21485343.
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  120. Lee YC, Chibnik LB, Lu B, Wasan AD, Edwards RR, Fossel AH, Helfgott SM, Solomon DH, Clauw DJ, Karlson EW. The relationship between disease activity, sleep, psychiatric distress and pain sensitivity in rheumatoid arthritis: a cross-sectional study. Arthritis Res Ther. 2009; 11(5):R160. PMID: 19874580; PMCID: PMC2787262.
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  122. Goodin BR, McGuire LM, Stapleton LM, Quinn NB, Fabian LA, Haythornthwaite JA, Edwards RR. Pain catastrophizing mediates the relationship between self-reported strenuous exercise involvement and pain ratings: moderating role of anxiety sensitivity. Psychosom Med. 2009 Nov; 71(9):1018-25. PMID: 19779141; PMCID: PMC2784988.
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  123. Backonja MM, Walk D, Edwards RR, Sehgal N, Moeller-Bertram T, Wasan A, Irving G, Argoff C, Wallace M. Quantitative sensory testing in measurement of neuropathic pain phenomena and other sensory abnormalities. Clin J Pain. 2009 Sep; 25(7):641-7. PMID: 19692807.
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  126. Smith MT, Wickwire EM, Grace EG, Edwards RR, Buenaver LF, Peterson S, Klick B, Haythornthwaite JA. Sleep disorders and their association with laboratory pain sensitivity in temporomandibular joint disorder. Sleep. 2009 Jun; 32(6):779-90. PMID: 19544755; PMCID: PMC2690566.
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  128. Celestin J, Edwards RR, Jamison RN. Pretreatment psychosocial variables as predictors of outcomes following lumbar surgery and spinal cord stimulation: a systematic review and literature synthesis. Pain Med. 2009 May-Jun; 10(4):639-53. PMID: 19638142.
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  131. Cohen LA, Bonito AJ, Akin DR, Manski RJ, Macek MD, Edwards RR, Cornelius LJ. Toothache pain: behavioral impact and self-care strategies. Spec Care Dentist. 2009 Mar-Apr; 29(2):85-95. PMID: 19284508.
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  133. Paller CJ, Campbell CM, Edwards RR, Dobs AS. Sex-based differences in pain perception and treatment. Pain Med. 2009 Mar; 10(2):289-99. PMID: 19207233; PMCID: PMC2745644.
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  134. Cohen LA, Harris SL, Bonito AJ, Manski RJ, Macek MD, Edwards RR, Khanna N, Plowden KO. Low-income and minority patient satisfaction with visits to emergency departments and physician offices for dental problems. J Am Coll Dent. 2009; 76(3):23-31. PMID: 19928365; PMCID: PMC2819232.
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  136. Cohen LA, Bonito AJ, Akin DR, Manski RJ, Macek MD, Edwards RR, Cornelius LJ. Role of pharmacists in consulting with the underserved regarding toothache pain. J Am Pharm Assoc (2003). 2009 Jan-Feb; 49(1):38-42. PMID: 19196595.
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  169. Edwards RR, Fillingim RB. Styles of pain coping predict cardiovascular function following a cold pressor test. Pain Res Manag. 2005; 10(4):219-22. PMID: 16341309.
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  171. Edwards RR, Haythornthwaite J. Mood swings: variability in the use of the Profile of Mood States. J Pain Symptom Manage. 2004 Dec; 28(6):534. PMID: 15589077.
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  172. Edwards RR, Ness TJ, Fillingim RB. Endogenous opioids, blood pressure, and diffuse noxious inhibitory controls: a preliminary study. Percept Mot Skills. 2004 Oct; 99(2):679-87. PMID: 15560360.
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  173. Edwards RR, Haythornthwaite JA, Sullivan MJ, Fillingim RB. Catastrophizing as a mediator of sex differences in pain: differential effects for daily pain versus laboratory-induced pain. Pain. 2004 Oct; 111(3):335-41. PMID: 15363877.
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  174. Smith MT, Edwards RR, Robinson RC, Dworkin RH. Suicidal ideation, plans, and attempts in chronic pain patients: factors associated with increased risk. Pain. 2004 Sep; 111(1-2):201-8. PMID: 15327824.
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  175. Edwards RR, Fillingim RB, Maixner W, Sigurdsson A, Haythornthwaite J. Catastrophizing predicts changes in thermal pain responses after resolution of acute dental pain. J Pain. 2004 Apr; 5(3):164-70. PMID: 15106129.
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  176. Edwards RR, Doleys DM, Lowery D, Fillingim RB. Pain tolerance as a predictor of outcome following multidisciplinary treatment for chronic pain: differential effects as a function of sex. Pain. 2003 Dec; 106(3):419-26. PMID: 14659525.
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  177. Edwards RR, Ness TJ, Weigent DA, Fillingim RB. Individual differences in diffuse noxious inhibitory controls (DNIC): association with clinical variables. Pain. 2003 Dec; 106(3):427-37. PMID: 14659526.
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  178. Fillingim RB, Doleys DM, Edwards RR, Lowery D. Spousal responses are differentially associated with clinical variables in women and men with chronic pain. Clin J Pain. 2003 Jul-Aug; 19(4):217-24. PMID: 12840615.
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  179. Fillingim RB, Doleys DM, Edwards RR, Lowery D. Clinical characteristics of chronic back pain as a function of gender and oral opioid use. Spine (Phila Pa 1976). 2003 Jan 15; 28(2):143-50. PMID: 12544931.
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  180. Edwards RR, Fillingim RB, Ness TJ. Age-related differences in endogenous pain modulation: a comparison of diffuse noxious inhibitory controls in healthy older and younger adults. Pain. 2003 Jan; 101(1-2):155-65. PMID: 12507710.
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  181. Fillingim RB, Edwards RR, Doleys DM. Re: McCraken et al., A comparison of blacks and whites seeking treatment for chronic pain. Clin J Pain 2001;17:249-55. Clin J Pain. 2002 Mar-Apr; 18(2):136-7. PMID: 11882779.
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  182. Edwards RR, Fillingim RB. Effects of age on temporal summation and habituation of thermal pain: clinical relevance in healthy older and younger adults. J Pain. 2001 Dec; 2(6):307-17. PMID: 14622810.
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  183. Fillingim RB, Edwards RR. The association of hormone replacement therapy with experimental pain responses in postmenopausal women. Pain. 2001 May; 92(1-2):229-34. PMID: 11323144.
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  184. Edwards RR, Doleys DM, Fillingim RB, Lowery D. Ethnic differences in pain tolerance: clinical implications in a chronic pain population. Psychosom Med. 2001 Mar-Apr; 63(2):316-23. PMID: 11292281.
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  185. Edwards RR, Fillingim RB. Age-associated differences in responses to noxious stimuli. J Gerontol A Biol Sci Med Sci. 2001 Mar; 56(3):M180-5. PMID: 11253160.
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  186. Fillingim RB, Edwards RR, Powell T. Sex-dependent effects of reported familial pain history on recent pain complaints and experimental pain responses. Pain. 2000 May; 86(1-2):87-94. PMID: 10779665.
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  187. Fillingim RB, Edwards RR, Powell T. The relationship of sex and clinical pain to experimental pain responses. Pain. 1999 Dec; 83(3):419-25. PMID: 10568849.
    View in: PubMed
  188. Edwards RR, Fillingim RB, Yamauchi S, Sigurdsson A, Bunting S, Mohorn SG, Maixner W. Effects of gender and acute dental pain on thermal pain responses. Clin J Pain. 1999 Sep; 15(3):233-7. PMID: 10524477.
    View in: PubMed
  189. Edwards RR, Fillingim RB. Ethnic differences in thermal pain responses. Psychosom Med. 1999 May-Jun; 61(3):346-54. PMID: 10367615.
    View in: PubMed
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