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Robert R Edwards, Ph.D.

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Research
research activities and funding
The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
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  1. R21DA041020 (EDWARDS, ROBERT R) Aug 1, 2016 - Jul 31, 2018
    NIH/NIDA
    Opioid-induced change in pain sensitivity and modulation: Links to opioid misuse
    Role: Principal Investigator
  2. R01AR064367 (EDWARDS, ROBERT R) May 12, 2014 - Jul 31, 2019
    NIH/NIAMS
    Brain Mechanisms Underlying CBT-Related Reductions in Fibromyalgia
    Role: Principal Investigator
  3. R21CA171316 (BASARIA, SHEHZAD) Apr 1, 2013 - Mar 31, 2015
    NIH/NCI
    Hypogonadism and Pain Perception in Androgen-Deprived Men with Prostate Cancer
    Role: Co-Principal Investigator
  4. R13NS083322 (EDWARDS, ROBERT R) Apr 1, 2013 - Mar 31, 2014
    NIH/NINDS
    Young Investigator Travel Support for 2013 APS Annual Scientific Meeting
    Role: Principal Investigator
  5. R21AR057920 (EDWARDS, ROBERT R) Aug 1, 2010 - Jul 31, 2013
    NIH/NIAMS
    Catastrophizing and Cytokine Responses to Acute Pain in the Rheumatic Diseases
    Role: Principal Investigator

Bibliographic
selected publications
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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  1. Wideman TH, Edwards RR, Walton DM, Martel MO, Hudon A, Seminowicz DA. The Multi-modal Assessment Model of Pain: A Novel Framework for Further Integrating the Subjective Pain Experience within Research and Practice. Clin J Pain. 2018 Nov 15. PMID: 30444733.
    View in: PubMed
  2. Huhn AS, Strain EC, Bigelow GE, Smith MT, Edwards RR, Tompkins DA. Analgesic Effects of Hydromorphone versus Buprenorphine in Buprenorphine-maintained Individuals. Anesthesiology. 2018 Nov 02. PMID: 30418214.
    View in: PubMed
  3. Loggia ML, Edwards RR. Brain Structural Alterations in Chronic Knee Osteoarthritis: What Can Treatment Effects Teach Us? Pain Med. 2018 Nov 01; 19(11):2099-2100. PMID: 30137638.
    View in: PubMed
  4. Dorado K, Schreiber KL, Koulouris A, Edwards RR, Napadow V, Lazaridou A. Interactive effects of pain catastrophizing and mindfulness on pain intensity in women with fibromyalgia. Health Psychol Open. 2018 Jul-Dec; 5(2):2055102918807406. PMID: 30364853.
    View in: PubMed
  5. Gagliano-Jucá T, Pencina KM, Ganz T, Travison TG, Kantoff PW, Nguyen PL, Taplin ME, Kibel AS, Li Z, Huang G, Edwards RR, Nemeth E, Basaria S. Mechanisms Responsible for Reduced Erythropoiesis during Androgen Deprivation Therapy in Men with Prostate Cancer. Am J Physiol Endocrinol Metab. 2018 Oct 16. PMID: 30325657.
    View in: PubMed
  6. Gagliano-Jucá T, Burak MF, Pencina KM, Li Z, Edwards RR, Travison TG, Basaria S. Metabolic Changes in Androgen-Deprived Nondiabetic Men With Prostate Cancer Are Not Mediated by Cytokines or aP2. J Clin Endocrinol Metab. 2018 Oct 01; 103(10):3900-3908. PMID: 30032274.
    View in: PubMed
  7. Jamison RN, Xu X, Wan L, Edwards RR, Ross EL. Determining Pain Catastrophizing From Daily Pain App Assessment Data: Role of Computer-Based Classification. J Pain. 2018 Sep 29. PMID: 30273687.
    View in: PubMed
  8. Albrecht DS, Forsberg A, Sandström A, Bergan C, Kadetoff D, Protsenko E, Lampa J, Lee YC, Höglund CO, Catana C, Cervenka S, Akeju O, Lekander M, Cohen G, Halldin C, Taylor N, Kim M, Hooker JM, Edwards RR, Napadow V, Kosek E, Loggia ML. Brain glial activation in fibromyalgia - A multi-site positron emission tomography investigation. Brain Behav Immun. 2018 Sep 14. PMID: 30223011.
    View in: PubMed
  9. Meints SM, Wang V, Edwards RR. Sex and Race Differences in Pain Sensitization among Patients with Chronic Low Back Pain. J Pain. 2018 Jul 17. PMID: 30025944.
    View in: PubMed
  10. Spivey TL, Gutowski ED, Zinboonyahgoon N, King TA, Dominici L, Edwards RR, Golshan M, Schreiber KL. Chronic Pain After Breast Surgery: A Prospective, Observational Study. Ann Surg Oncol. 2018 Oct; 25(10):2917-2924. PMID: 30014456.
    View in: PubMed
  11. Lazaridou A, Martel MO, Cornelius M, Franceschelli O, Campbell C, Smith M, Haythornthwaite JA, Wright JR, Edwards RR. The Association Between Daily Physical Activity and Pain Among Patients with Knee Osteoarthritis: The Moderating Role of Pain Catastrophizing. Pain Med. 2018 Jul 16. PMID: 30016486.
    View in: PubMed
  12. Ellingsen DM, Napadow V, Protsenko E, Mawla I, Kowalski MH, Swensen D, O'Dwyer-Swensen D, Edwards RR, Kettner N, Loggia ML. Brain Mechanisms of Anticipated Painful Movements and Their Modulation by Manual Therapy in Chronic Low Back Pain. J Pain. 2018 Nov; 19(11):1352-1365. PMID: 30392530.
    View in: PubMed
  13. Cohen EM, Edwards RR, Bingham CO, Phillips K, Bolster MB, Moreland LW, Neogi T, Marder W, Wohlfahrt A, Clauw D, Lee YC. Pain and Catastrophizing in Patients With Rheumatoid Arthritis: A Prospective Observational Cohort Study. J Clin Rheumatol. 2018 Jun 22. PMID: 30035754.
    View in: PubMed
  14. Lee J, Protsenko E, Lazaridou A, Franceschelli O, Ellingsen DM, Mawla I, Isenburg K, Berry MP, Galenkamp L, Loggia ML, Wasan AD, Edwards RR, Napadow V. Encoding of Self-Referential Pain Catastrophizing in the Posterior Cingulate Cortex in Fibromyalgia. Arthritis Rheumatol. 2018 Aug; 70(8):1308-1318. PMID: 29579370.
    View in: PubMed
  15. Sieberg CB, Taras C, Gomaa A, Nickerson C, Wong C, Ward C, Baskozos G, Bennett DLH, Ramirez JD, Themistocleous AC, Rice ASC, Shillo PR, Tesfaye S, Edwards RR, Andrews NA, Berde C, Costigan M. Neuropathic pain drives anxiety behavior in mice, results consistent with anxiety levels in diabetic neuropathy patients. Pain Rep. 2018 May; 3(3):e651. PMID: 29922743.
    View in: PubMed
  16. Lee YC, Fine A, Protsenko E, Massarotti E, Edwards RR, Mawla I, Napadow V, Loggia ML. Brain Correlates of Continuous Pain in Rheumatoid Arthritis as Measured by Pulsed Arterial Spin Labeling. Arthritis Care Res (Hoboken). 2018 May 21. PMID: 29781581.
    View in: PubMed
  17. Price TJ, Basbaum AI, Bresnahan J, Chambers JF, De Koninck Y, Edwards RR, Ji RR, Katz J, Kavelaars A, Levine JD, Porter L, Schechter N, Sluka KA, Terman GW, Wager TD, Yaksh TL, Dworkin RH. Transition to chronic pain: opportunities for novel therapeutics. Nat Rev Neurosci. 2018 May 15. PMID: 29765159.
    View in: PubMed
  18. Jamison RN, Mei A, Edwards RR, Ross EL. Efficacy of Vibrating Gloves for Chronic Hand Pain due to Osteoarthritis. Pain Med. 2018 May 01; 19(5):1044-1057. PMID: 29025096.
    View in: PubMed
  19. Gagliano-Jucá T, Travison TG, Kantoff PW, Nguyen PL, Taplin ME, Kibel AS, Huang G, Bearup R, Schram H, Manley R, Beleva YM, Edwards RR, Basaria S. Androgen Deprivation Therapy Is Associated With Prolongation of QTc Interval in Men With Prostate Cancer. J Endocr Soc. 2018 May 01; 2(5):485-496. PMID: 29761176.
    View in: PubMed
  20. Lazaridou A, Martel MO, Cahalan CM, Cornelius MC, Franceschelli O, Campbell CM, Haythornthwaite JA, Smith M, Riley J, Edwards RR. The impact of anxiety and catastrophizing on interleukin-6 responses to acute painful stress. J Pain Res. 2018; 11:637-647. PMID: 29636630.
    View in: PubMed
  21. Abrecht CR, Cornelius M, Wu A, Jamison RN, Janfaza D, Urman RD, Campbell C, Smith M, Haythornthwaite J, Edwards RR, Schreiber KL. Prediction of Pain and Opioid Utilization in the Perioperative Period in Patients Undergoing Primary Knee Arthroplasty: Psychophysical and Psychosocial Factors. Pain Med. 2018 Mar 07. PMID: 29522115.
    View in: PubMed
  22. Mariano TY, Urman RD, Hutchison CA, Jamison RN, Edwards RR. Cognitive Behavioral Therapy (CBT) for Subacute Low Back Pain: a Systematic Review. Curr Pain Headache Rep. 2018 Feb 23; 22(3):15. PMID: 29476270.
    View in: PubMed
  23. Lee YC, Bingham CO, Edwards RR, Marder W, Phillips K, Bolster MB, Clauw DJ, Moreland LW, Lu B, Wohlfahrt A, Zhang Z, Neogi T. Association Between Pain Sensitization and Disease Activity in Patients With Rheumatoid Arthritis: A Cross-Sectional Study. Arthritis Care Res (Hoboken). 2018 Feb; 70(2):197-204. PMID: 28437846.
    View in: PubMed
  24. Meints SM, Edwards RR. Evaluating psychosocial contributions to chronic pain outcomes. Prog Neuropsychopharmacol Biol Psychiatry. 2018 Dec 20; 87(Pt B):168-182. PMID: 29408484.
    View in: PubMed
  25. Gollub RL, Kirsch I, Maleki N, Wasan AD, Edwards RR, Tu Y, Kaptchuk TJ, Kong J. A Functional Neuroimaging Study of Expectancy Effects on Pain Response in Patients With Knee Osteoarthritis. J Pain. 2018 May; 19(5):515-527. PMID: 29325883.
    View in: PubMed
  26. Chai PR, Carreiro S, Innes BJ, Chapman B, Schreiber KL, Edwards RR, Carrico AW, Boyer EW. Oxycodone Ingestion Patterns in Acute Fracture Pain With Digital Pills. Anesth Analg. 2017 12; 125(6):2105-2112. PMID: 29189367.
    View in: PubMed
  27. Gagliano-Jucá T, Travison TG, Nguyen PL, Kantoff PW, Taplin ME, Kibel AS, Manley R, Hally K, Bearup R, Beleva YM, Huang G, Edwards RR, Basaria S. Effects of Androgen Deprivation Therapy on Pain Perception, Quality of Life, and Depression in Men With Prostate Cancer. J Pain Symptom Manage. 2018 Feb; 55(2):307-317.e1. PMID: 28941963.
    View in: PubMed
  28. Tompkins DA, Huhn AS, Johnson PS, Smith MT, Strain EC, Edwards RR, Johnson MW. To take or not to take: the association between perceived addiction risk, expected analgesic response and likelihood of trying novel pain relievers in self-identified chronic pain patients. Addiction. 2018 Jan; 113(1):67-79. PMID: 28645137.
    View in: PubMed
  29. Garcia RG, Lin RL, Lee J, Kim J, Barbieri R, Sclocco R, Wasan AD, Edwards RR, Rosen BR, Hadjikhani N, Napadow V. Modulation of brainstem activity and connectivity by respiratory-gated auricular vagal afferent nerve stimulation in migraine patients. Pain. 2017 08; 158(8):1461-1472. PMID: 28541256.
    View in: PubMed
  30. Jamison RN, Jurcik DC, Edwards RR, Huang CC, Ross EL. A Pilot Comparison of a Smartphone App With or Without 2-Way Messaging Among Chronic Pain Patients: Who Benefits From a Pain App? Clin J Pain. 2017 Aug; 33(8):676-686. PMID: 27898460.
    View in: PubMed
  31. Sundararaman LV, Edwards RR, Ross EL, Jamison RN. Integration of Mobile Health Technology in the Treatment of Chronic Pain: A Critical Review. Reg Anesth Pain Med. 2017 Jul/Aug; 42(4):488-498. PMID: 28570436.
    View in: PubMed
  32. Berna C, Kirsch I, Zion SR, Lee YC, Jensen KB, Sadler P, Kaptchuk TJ, Edwards RR. Side effects can enhance treatment response through expectancy effects: an experimental analgesic randomized controlled trial. Pain. 2017 06; 158(6):1014-1020. PMID: 28178072.
    View in: PubMed
  33. Huang G, Travison TG, Edwards RR, Basaria S. Effects of Testosterone Replacement on Pain Catastrophizing and Sleep Quality in Men with Opioid-Induced Androgen Deficiency. Pain Med. 2017 06 01; 18(6):1070-1076. PMID: 27550959.
    View in: PubMed
  34. Riley JL, Cruz-Almeida Y, Dasilva Ribeiro MC, Simon CB, Eckert NR, Aguirre M, Sorenson HL, Tighe PJ, Edwards RR, Wallet SM. Age Differences in the Time Course and Magnitude of Changes in Circulating Neuropeptides After Pain Evocation in Humans. J Pain. 2017 Sep; 18(9):1078-1086. PMID: 28461253.
    View in: PubMed
  35. Zghoul N, Ross EL, Edwards RR, Ahmed A, Jamison RN. Prevalence of chronic pain with neuropathic characteristics: a randomized telephone survey among medical center patients in Kuwait. J Pain Res. 2017; 10:679-687. PMID: 28435312.
    View in: PubMed
  36. Schreiber KL, Loggia ML, Kim J, Cahalan CM, Napadow V, Edwards RR. Painful After-Sensations in Fibromyalgia are Linked to Catastrophizing and Differences in Brain Response in the Medial Temporal Lobe. J Pain. 2017 Jul; 18(7):855-867. PMID: 28300650.
    View in: PubMed
  37. Jamison RN, Dorado K, Mei A, Edwards RR, Martel MO. Influence of opioid-related side effects on disability, mood, and opioid misuse risk among patients with chronic pain in primary care. Pain Rep. 2017 Mar; 2(2):e589. PMID: 29392205.
    View in: PubMed
  38. Lazaridou A, Kim J, Cahalan CM, Loggia ML, Franceschelli O, Berna C, Schur P, Napadow V, Edwards RR. Effects of Cognitive-Behavioral Therapy (CBT) on Brain Connectivity Supporting Catastrophizing in Fibromyalgia. Clin J Pain. 2017 03; 33(3):215-221. PMID: 27518491.
    View in: PubMed
  39. Smith SM, Dworkin RH, Turk DC, Baron R, Polydefkis M, Tracey I, Borsook D, Edwards RR, Harris RE, Wager TD, Arendt-Nielsen L, Burke LB, Carr DB, Chappell A, Farrar JT, Freeman R, Gilron I, Goli V, Haeussler J, Jensen T, Katz NP, Kent J, Kopecky EA, Lee DA, Maixner W, Markman JD, McArthur JC, McDermott MP, Parvathenani L, Raja SN, Rappaport BA, Rice ASC, Rowbotham MC, Tobias JK, Wasan AD, Witter J. The Potential Role of Sensory Testing, Skin Biopsy, and Functional Brain Imaging as Biomarkers in Chronic Pain Clinical Trials: IMMPACT Considerations. J Pain. 2017 Jul; 18(7):757-777. PMID: 28254585.
    View in: PubMed
  40. Dworkin RH, Edwards RR. Phenotypes and treatment response: it's difficult to make predictions, especially about the future. Pain. 2017 02; 158(2):187-189. PMID: 28092645.
    View in: PubMed
  41. Mathur VA, Kiley KB, Haywood C, Bediako SM, Lanzkron S, Carroll CP, Buenaver LF, Pejsa M, Edwards RR, Haythornthwaite JA, Campbell CM. Multiple Levels of Suffering: Discrimination in Health-Care Settings is Associated With Enhanced Laboratory Pain Sensitivity in Sickle Cell Disease. Clin J Pain. 2016 12; 32(12):1076-1085. PMID: 26889615.
    View in: PubMed
  42. Chen X, Spaeth RB, Freeman SG, Scarborough DM, Hashmi JA, Wey HY, Egorova N, Vangel M, Mao J, Wasan AD, Edwards RR, Gollub RL, Kong J. The Modulation Effect of Longitudinal Acupuncture on Resting State Functional Connectivity in Knee Osteoarthritis Patients. Mol Pain. 2015 01; 11. PMID: 27655921.
    View in: PubMed
  43. Edwards RR, Dworkin RH, Turk DC, Angst MS, Dionne R, Freeman R, Hansson P, Haroutounian S, Arendt-Nielsen L, Attal N, Baron R, Brell J, Bujanover S, Burke LB, Carr D, Chappell AS, Cowan P, Etropolski M, Fillingim RB, Gewandter JS, Katz NP, Kopecky EA, Markman JD, Nomikos G, Porter L, Rappaport BA, Rice AS, Scavone JM, Scholz J, Simon LS, Smith SM, Tobias J, Tockarshewsky T, Veasley C, Versavel M, Wasan AD, Wen W, Yarnitsky D. Patient phenotyping in clinical trials of chronic pain treatments: IMMPACT recommendations. Pain. 2016 Sep; 157(9):1851-71. PMID: 27152687.
    View in: PubMed
  44. Fillingim RB, Loeser JD, Baron R, Edwards RR. Assessment of Chronic Pain: Domains, Methods, and Mechanisms. J Pain. 2016 09; 17(9 Suppl):T10-20. PMID: 27586827.
    View in: PubMed
  45. Edwards RR, Dworkin RH, Sullivan MD, Turk DC, Wasan AD. The Role of Psychosocial Processes in the Development and Maintenance of Chronic Pain. J Pain. 2016 09; 17(9 Suppl):T70-92. PMID: 27586832.
    View in: PubMed
  46. Mathur VA, Kiley KB, Carroll CP, Edwards RR, Lanzkron S, Haythornthwaite JA, Campbell CM. Disease-Related, Nondisease-Related, and Situational Catastrophizing in Sickle Cell Disease and Its Relationship With Pain. J Pain. 2016 11; 17(11):1227-1236. PMID: 27555427.
    View in: PubMed
  47. Lee J, Lin RL, Garcia RG, Kim J, Kim H, Loggia ML, Mawla I, Wasan AD, Edwards RR, Rosen BR, Hadjikhani N, Napadow V. Reduced insula habituation associated with amplification of trigeminal brainstem input in migraine. Cephalalgia. 2017 Oct; 37(11):1026-1038. PMID: 27521844.
    View in: PubMed
  48. Tompkins DA, Johnson PS, Smith MT, Strain EC, Edwards RR, Johnson MW. Temporal preference in individuals reporting chronic pain: discounting of delayed pain-related and monetary outcomes. Pain. 2016 08; 157(8):1724-32. PMID: 27075431.
    View in: PubMed
  49. Edwards RR, Dolman AJ, Martel MO, Finan PH, Lazaridou A, Cornelius M, Wasan AD. Variability in conditioned pain modulation predicts response to NSAID treatment in patients with knee osteoarthritis. BMC Musculoskelet Disord. 2016 07 13; 17:284. PMID: 27412526; PMCID: PMC4944243.
    View in: PubMed, PubMed Central
  50. Tsui JI, Lira MC, Cheng DM, Winter MR, Alford DP, Liebschutz JM, Edwards RR, Samet JH. Chronic pain, craving, and illicit opioid use among patients receiving opioid agonist therapy. Drug Alcohol Depend. 2016 09 01; 166:26-31. PMID: 27422763; PMCID: PMC4983520 [Available on 09/01/17].
    View in: PubMed, PubMed Central
  51. Huang G, Travison T, Maggio M, Edwards RR, Basaria S. Effects of testosterone replacement on metabolic and inflammatory markers in men with opioid-induced androgen deficiency. Clin Endocrinol (Oxf). 2016 08; 85(2):232-8. PMID: 26928845.
    View in: PubMed
  52. McHugh RK, Weiss RD, Cornelius M, Martel MO, Jamison RN, Edwards RR. Distress Intolerance and Prescription Opioid Misuse Among Patients With Chronic Pain. J Pain. 2016 07; 17(7):806-14. PMID: 27058161; PMCID: PMC4925301 [Available on 07/01/17].
    View in: PubMed, PubMed Central
  53. Campbell CM, Carroll CP, Kiley K, Han D, Haywood C, Lanzkron S, Swedberg L, Edwards RR, Page GG, Haythornthwaite JA. Quantitative sensory testing and pain-evoked cytokine reactivity: comparison of patients with sickle cell disease to healthy matched controls. Pain. 2016 Apr; 157(4):949-56. PMID: 26713424; PMCID: PMC4932897 [Available on 04/01/17].
    View in: PubMed, PubMed Central
  54. Basaria S, Edwards RR, Travison TG. Reply. Pain. 2016 Apr; 157(4):990-1. PMID: 26982516.
    View in: PubMed
  55. Wideman TH, Edwards RR, Finan PH, Haythornthwaite JA, Smith MT. Comparing the Predictive Value of Task Performance and Task-Specific Sensitivity During Physical Function Testing Among People With Knee Osteoarthritis. J Orthop Sports Phys Ther. 2016 May; 46(5):346-56. PMID: 26999411.
    View in: PubMed
  56. Martel MO, Finan PH, McHugh RK, Issa M, Edwards RR, Jamison RN, Wasan AD. Day-to-day pain symptoms are only weakly associated with opioid craving among patients with chronic pain prescribed opioid therapy. Drug Alcohol Depend. 2016 May 01; 162:130-6. PMID: 27021805; PMCID: PMC4833606 [Available on 05/01/17].
    View in: PubMed, PubMed Central
  57. Edwards RR, Dolman AJ, Michna E, Katz JN, Nedeljkovic SS, Janfaza D, Isaac Z, Martel MO, Jamison RN, Wasan AD. Changes in Pain Sensitivity and Pain Modulation During Oral Opioid Treatment: The Impact of Negative Affect. Pain Med. 2016 10; 17(10):1882-1891. PMID: 26933094.
    View in: PubMed
  58. Martel MO, Olesen AE, Jørgensen D, Nielsen LM, Brock C, Edwards RR, Drewes AM. Does catastrophic thinking enhance oesophageal pain sensitivity? An experimental investigation. Eur J Pain. 2016 09; 20(8):1214-22. PMID: 26919233.
    View in: PubMed
  59. Campbell CM, Moscou-Jackson G, Carroll CP, Kiley K, Haywood C, Lanzkron S, Hand M, Edwards RR, Haythornthwaite JA. An Evaluation of Central Sensitization in Patients With Sickle Cell Disease. J Pain. 2016 05; 17(5):617-27. PMID: 26892240; PMCID: PMC4851873 [Available on 05/01/17].
    View in: PubMed, PubMed Central
  60. Lazaridou A, Edwards RR. Getting personal: the role of individual patient preferences and characteristics in shaping pain treatment outcomes. Pain. 2016 Jan; 157(1):1-2. PMID: 26447708.
    View in: PubMed
  61. Jamison RN, Martel MO, Huang CC, Jurcik D, Edwards RR. Efficacy of the Opioid Compliance Checklist to Monitor Chronic Pain Patients Receiving Opioid Therapy in Primary Care. J Pain. 2016 Apr; 17(4):414-23. PMID: 26705974.
    View in: PubMed
  62. Lee YC, Massarotti E, Edwards RR, Lu B, Liu C, Lo Y, Wohlfahrt A, Kim ND, Clauw DJ, Solomon DH. Effect of Milnacipran on Pain in Patients with Rheumatoid Arthritis with Widespread Pain: A Randomized Blinded Crossover Trial. J Rheumatol. 2016 Jan; 43(1):38-45. PMID: 26628607; PMCID: PMC4698221.
    View in: PubMed, PubMed Central
  63. Chen X, Spaeth RB, Freeman SG, Scarborough DM, Hashmi JA, Wey HY, Egorova N, Vangel M, Mao J, Wasan AD, Edwards RR, Gollub RL, Kong J. The modulation effect of longitudinal acupuncture on resting state functional connectivity in knee osteoarthritis patients. Mol Pain. 2015 Oct 29; 11:67. PMID: 26511911; PMCID: PMC4625557.
    View in: PubMed, PubMed Central
  64. Wasan AD, Michna E, Edwards RR, Katz JN, Nedeljkovic SS, Dolman AJ, Janfaza D, Isaac Z, Jamison RN. Psychiatric Comorbidity Is Associated Prospectively with Diminished Opioid Analgesia and Increased Opioid Misuse in Patients with Chronic Low Back Pain. Anesthesiology. 2015 Oct; 123(4):861-72. PMID: 26375824; PMCID: PMC4573512 [Available on 10/01/16].
    View in: PubMed, PubMed Central
  65. Campbell CM, Buenaver LF, Finan P, Bounds SC, Redding M, McCauley L, Robinson M, Edwards RR, Smith MT. Sleep, Pain Catastrophizing, and Central Sensitization in Knee Osteoarthritis Patients With and Without Insomnia. Arthritis Care Res (Hoboken). 2015 Oct; 67(10):1387-96. PMID: 26041510; PMCID: PMC4580506 [Available on 10/01/16].
    View in: PubMed, PubMed Central
  66. Deeny MC, Al Hamdan E, Ross EL, Edwards RR, Huang CC, Jamison RN. Chronic Pain, Comorbid Medical Conditions, and Associated Risk Factors in Kuwait: Gender and Nationality Differences. Pain Med. 2015 Nov; 16(11):2204-11. PMID: 26118589.
    View in: PubMed
  67. Martel MO, Finan PH, Dolman AJ, Subramanian S, Edwards RR, Wasan AD, Jamison RN. Self-reports of medication side effects and pain-related activity interference in patients with chronic pain: a longitudinal cohort study. Pain. 2015 Jun; 156(6):1092-100. PMID: 25782367; PMCID: PMC4431924.
    View in: PubMed, PubMed Central
  68. Tsui JI, Lira MC, Cheng DM, Winter MR, Alford DP, Liebschutz JM, Mao J, Edwards RR, Samet JH. Hepatitis C virus infection and pain sensitivity in patients on methadone or buprenorphine maintenance therapy for opioid use disorders. Drug Alcohol Depend. 2015 Aug 01; 153:286-92. PMID: 26048638; PMCID: PMC4509826.
    View in: PubMed, PubMed Central
  69. Kim J, Loggia ML, Cahalan CM, Harris RE, Beissner F, Garcia RG, Kim H, Wasan AD, Edwards RR, Napadow V. The somatosensory link in fibromyalgia: functional connectivity of the primary somatosensory cortex is altered by sustained pain and is associated with clinical/autonomic dysfunction. Arthritis Rheumatol. 2015 May; 67(5):1395-1405. PMID: 25622796; PMCID: PMC4414820.
    View in: PubMed, PubMed Central
  70. Loggia ML, Berna C, Kim J, Cahalan CM, Martel MO, Gollub RL, Wasan AD, Napadow V, Edwards RR. The lateral prefrontal cortex mediates the hyperalgesic effects of negative cognitions in chronic pain patients. J Pain. 2015 Aug; 16(8):692-9. PMID: 25937162.
    View in: PubMed
  71. Kim H, Kim J, Loggia ML, Cahalan C, Garcia RG, Vangel MG, Wasan AD, Edwards RR, Napadow V. Fibromyalgia is characterized by altered frontal and cerebellar structural covariance brain networks. Neuroimage Clin. 2015; 7:667-77. PMID: 25844321; PMCID: PMC4379388.
    View in: PubMed, PubMed Central
  72. Katz NP, Paillard FC, Edwards RR. Review of the performance of quantitative sensory testing methods to detect hyperalgesia in chronic pain patients on long-term opioids. Anesthesiology. 2015 Mar; 122(3):677-85. PMID: 25437498.
    View in: PubMed
  73. Smith SM, Paillard F, McKeown A, Burke LB, Edwards RR, Katz NP, Papadopoulos EJ, Rappaport BA, Slagle A, Strain EC, Wasan AD, Turk DC, Dworkin RH. Instruments to Identify Prescription Medication Misuse, Abuse, and Related Events in Clinical Trials: An ACTTION Systematic Review. J Pain. 2015 May; 16(5):389-411. PMID: 25660826.
    View in: PubMed
  74. Basaria S, Travison TG, Alford D, Knapp PE, Teeter K, Cahalan C, Eder R, Lakshman K, Bachman E, Mensing G, Martel MO, Le D, Stroh H, Bhasin S, Wasan AD, Edwards RR. Effects of testosterone replacement in men with opioid-induced androgen deficiency: a randomized controlled trial. Pain. 2015 Feb; 156(2):280-8. PMID: 25599449.
    View in: PubMed
  75. Loggia ML, Chonde DB, Akeju O, Arabasz G, Catana C, Edwards RR, Hill E, Hsu S, Izquierdo-Garcia D, Ji RR, Riley M, Wasan AD, Zürcher NR, Albrecht DS, Vangel MG, Rosen BR, Napadow V, Hooker JM. Evidence for brain glial activation in chronic pain patients. Brain. 2015 Mar; 138(Pt 3):604-15. PMID: 25582579.
    View in: PubMed
  76. Schreiber KL, Campbell C, Martel MO, Greenbaum S, Wasan AD, Borsook D, Jamison RN, Edwards RR. Distraction analgesia in chronic pain patients: the impact of catastrophizing. Anesthesiology. 2014 Dec; 121(6):1292-301. PMID: 25264596.
    View in: PubMed
  77. Dolman AJ, Loggia ML, Edwards RR, Gollub RL, Kong J, Napadow V, Wasan AD. Phenotype matters: the absence of a positive association between cortical thinning and chronic low back pain when controlling for salient clinical variables. Clin J Pain. 2014 Oct; 30(10):839-45. PMID: 24135900; PMCID: PMC4103969.
    View in: PubMed, PubMed Central
  78. Hsieh C, Kong J, Kirsch I, Edwards RR, Jensen KB, Kaptchuk TJ, Gollub RL. Well-loved music robustly relieves pain: a randomized, controlled trial. PLoS One. 2014; 9(9):e107390. PMID: 25211164; PMCID: PMC4161415.
    View in: PubMed, PubMed Central
  79. Jamison RN, Martel MO, Edwards RR, Qian J, Sheehan KA, Ross EL. Validation of a brief Opioid Compliance Checklist for patients with chronic pain. J Pain. 2014 Nov; 15(11):1092-1101. PMID: 25092233.
    View in: PubMed
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  84. Schreiber KL, Kehlet H, Belfer I, Edwards RR. Predicting, preventing and managing persistent pain after breast cancer surgery: the importance of psychosocial factors. Pain Manag. 2014; 4(6):445-59. PMID: 25494696.
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  86. Wideman TH, Finan PH, Edwards RR, Quartana PJ, Buenaver LF, Haythornthwaite JA, Smith MT. Increased sensitivity to physical activity among individuals with knee osteoarthritis: relation to pain outcomes, psychological factors, and responses to quantitative sensory testing. Pain. 2014 Apr; 155(4):703-11. PMID: 24378879.
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  88. Campbell CM, Bounds SC, Kuwabara H, Edwards RR, Campbell JN, Haythornthwaite JA, Smith MT. individual variation in sleep quality and duration is related to cerebral mu opioid receptor binding potential during tonic laboratory pain in healthy subjects. Pain Med. 2013 Dec; 14(12):1882-92. PMID: 24102962; PMCID: PMC4104524.
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  90. Belfer I, Schreiber KL, Shaffer JR, Shnol H, Blaney K, Morando A, Englert D, Greco C, Brufsky A, Ahrendt G, Kehlet H, Edwards RR, Bovbjerg DH. Persistent postmastectomy pain in breast cancer survivors: analysis of clinical, demographic, and psychosocial factors. J Pain. 2013 Oct; 14(10):1185-95. PMID: 23890847.
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  91. Spaeth RB, Camhi S, Hashmi JA, Vangel M, Wasan AD, Edwards RR, Gollub RL, Kong J. A longitudinal study of the reliability of acupuncture deqi sensations in knee osteoarthritis. Evid Based Complement Alternat Med. 2013; 2013:204259. PMID: 23935656; PMCID: PMC3713327.
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  92. Smith SM, Dart RC, Katz NP, Paillard F, Adams EH, Comer SD, Degroot A, Edwards RR, Haddox JD, Jaffe JH, Jones CM, Kleber HD, Kopecky EA, Markman JD, Montoya ID, O'Brien C, Roland CL, Stanton M, Strain EC, Vorsanger G, Wasan AD, Weiss RD, Turk DC, Dworkin RH. Classification and definition of misuse, abuse, and related events in clinical trials: ACTTION systematic review and recommendations. Pain. 2013 Nov; 154(11):2287-96. PMID: 23792283.
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  94. Backonja MM, Attal N, Baron R, Bouhassira D, Drangholt M, Dyck PJ, Edwards RR, Freeman R, Gracely R, Haanpaa MH, Hansson P, Hatem SM, Krumova EK, Jensen TS, Maier C, Mick G, Rice AS, Rolke R, Treede RD, Serra J, Toelle T, Tugnoli V, Walk D, Walalce MS, Ware M, Yarnitsky D, Ziegler D. Value of quantitative sensory testing in neurological and pain disorders: NeuPSIG consensus. Pain. 2013 Sep; 154(9):1807-19. PMID: 23742795.
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  98. Finan PH, Buenaver LF, Bounds SC, Hussain S, Park RJ, Haque UJ, Campbell CM, Haythornthwaite JA, Edwards RR, Smith MT. Discordance between pain and radiographic severity in knee osteoarthritis: findings from quantitative sensory testing of central sensitization. Arthritis Rheum. 2013 Feb; 65(2):363-72. PMID: 22961435; PMCID: PMC3863776.
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  99. Campbell CM, Jamison RN, Edwards RR. Psychological screening/phenotyping as predictors for spinal cord stimulation. Curr Pain Headache Rep. 2013 Jan; 17(1):307. PMID: 23247806; PMCID: PMC3601592.
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  100. Lee YC, Lu B, Edwards RR, Wasan AD, Nassikas NJ, Clauw DJ, Solomon DH, Karlson EW. The role of sleep problems in central pain processing in rheumatoid arthritis. Arthritis Rheum. 2013 Jan; 65(1):59-68. PMID: 23124650; PMCID: PMC3535519.
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  108. Goodin BR, Quinn NB, King CD, Page GG, Haythornthwaite JA, Edwards RR, Stapleton LM, McGuire L. Enhanced cortisol increase upon awakening is associated with greater pain ratings but not salivary cortisol or soluble tumor necrosis factor-a receptor II responses to acute pain. Clin J Pain. 2012 May; 28(4):291-9. PMID: 21904196; PMCID: PMC3237812.
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  118. Cohen LA, Bonito AJ, Eicheldinger C, Manski RJ, Edwards RR, Khanna N. Health literacy impact on patient-provider interactions involving the treatment of dental problems. J Dent Educ. 2011 Sep; 75(9):1218-24. PMID: 21890851; PMCID: PMC3303161.
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  119. Lucey BP, Clifford DB, Creighton J, Edwards RR, McArthur JC, Haythornthwaite J. Relationship of depression and catastrophizing to pain, disability, and medication adherence in patients with HIV-associated sensory neuropathy. AIDS Care. 2011 Aug; 23(8):921-8. PMID: 21500021; PMCID: PMC4418482.
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  121. McCann UD, Edwards RR, Smith MT, Kelley K, Wilson M, Sgambati F, Ricaurte G. Altered pain responses in abstinent (±)3,4-methylenedioxymethamphetamine (MDMA, "ecstasy") users. Psychopharmacology (Berl). 2011 Oct; 217(4):475-84. PMID: 21603895.
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  123. Edwards RR, Cahalan C, Calahan C, Mensing G, Smith M, Haythornthwaite JA. Pain, catastrophizing, and depression in the rheumatic diseases. Nat Rev Rheumatol. 2011 Apr; 7(4):216-24. PMID: 21283147.
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  129. Coughlin JW, Edwards RR, Redgrave GW, Guarda AS. Pain severity in eating disorders predicts longer inpatient hospitalization. Int J Eat Disord. 2010 Dec; 43(8):737-42. PMID: 19842161.
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  139. Lee YC, Chibnik LB, Lu B, Wasan AD, Edwards RR, Fossel AH, Helfgott SM, Solomon DH, Clauw DJ, Karlson EW. The relationship between disease activity, sleep, psychiatric distress and pain sensitivity in rheumatoid arthritis: a cross-sectional study. Arthritis Res Ther. 2009; 11(5):R160. PMID: 19874580; PMCID: PMC2787262.
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  147. Celestin J, Edwards RR, Jamison RN. Pretreatment psychosocial variables as predictors of outcomes following lumbar surgery and spinal cord stimulation: a systematic review and literature synthesis. Pain Med. 2009 May-Jun; 10(4):639-53. PMID: 19638142.
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  165. Edwards RR, Smith MT, Klick B, Magyar-Russell G, Haythornthwaite JA, Holavanahalli R, Patterson DR, Blakeney P, Lezotte D, McKibben J, Fauerbach JA. Symptoms of depression and anxiety as unique predictors of pain-related outcomes following burn injury. Ann Behav Med. 2007 Nov-Dec; 34(3):313-22. PMID: 18020941.
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  166. Kudel I, Edwards RR, Kozachik S, Block BM, Agarwal S, Heinberg LJ, Haythornthwaite J, Raja SN. Predictors and consequences of multiple persistent postmastectomy pains. J Pain Symptom Manage. 2007 Dec; 34(6):619-27. PMID: 17629668.
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  167. Smith MT, Edwards RR, McCann UD, Haythornthwaite JA. The effects of sleep deprivation on pain inhibition and spontaneous pain in women. Sleep. 2007 Apr; 30(4):494-505. PMID: 17520794.
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  168. Cohen LA, Harris SL, Bonito AJ, Manski RJ, Macek MD, Edwards RR, Cornelius LJ. Coping with toothache pain: a qualitative study of low-income persons and minorities. J Public Health Dent. 2007; 67(1):28-35. PMID: 17436976.
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  169. Edwards RR, Klick B, Buenaver L, Max MB, Haythornthwaite JA, Keller RB, Atlas SJ. Symptoms of distress as prospective predictors of pain-related sciatica treatment outcomes. Pain. 2007 Jul; 130(1-2):47-55. PMID: 17156925.
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  170. Edwards RR. Genetic predictors of acute and chronic pain. Curr Rheumatol Rep. 2006 Dec; 8(6):411-7. PMID: 17092439.
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  171. Edwards RR, Fillingim RB. Self-reported pain sensitivity: lack of correlation with pain threshold and tolerance. Eur J Pain. 2007 Jul; 11(5):594-8. PMID: 17118681; PMCID: PMC1974872.
    View in: PubMed, PubMed Central
  172. Buenaver LF, Edwards RR, Haythornthwaite JA. Pain-related catastrophizing and perceived social responses: Inter-relationships in the context of chronic pain. Pain. 2007 Feb; 127(3):234-42. PMID: 17011706; PMCID: PMC1866270.
    View in: PubMed, PubMed Central
  173. Edwards RR, Smith MT, Stonerock G, Haythornthwaite JA. Pain-related catastrophizing in healthy women is associated with greater temporal summation of and reduced habituation to thermal pain. Clin J Pain. 2006 Oct; 22(8):730-7. PMID: 16988570.
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  174. Edwards RR, Goble L, Kwan A, Kudel I, McGuire L, Heinberg L, Wigley F, Haythornthwaite J. Catastrophizing, pain, and social adjustment in scleroderma: relationships with educational level. Clin J Pain. 2006 Sep; 22(7):639-46. PMID: 16926580.
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  175. Edwards RR, Smith MT, Kudel I, Haythornthwaite J. Pain-related catastrophizing as a risk factor for suicidal ideation in chronic pain. Pain. 2006 Dec 15; 126(1-3):272-9. PMID: 16926068.
    View in: PubMed
  176. Edwards RR, Haythornthwaite JA, Tella P, Max MB, Raja S. Basal heat pain thresholds predict opioid analgesia in patients with postherpetic neuralgia. Anesthesiology. 2006 Jun; 104(6):1243-8. PMID: 16732096.
    View in: PubMed
  177. Max MB, Wu T, Atlas SJ, Edwards RR, Haythornthwaite JA, Bollettino AF, Hipp HS, McKnight CD, Osman IA, Crawford EN, Pao M, Nejim J, Kingman A, Aisen DC, Scully MA, Keller RB, Goldman D, Belfer I. A clinical genetic method to identify mechanisms by which pain causes depression and anxiety. Mol Pain. 2006 Apr 19; 2:14. PMID: 16623937; PMCID: PMC1488826.
    View in: PubMed, PubMed Central
  178. Edwards RR, Bingham CO, Bathon J, Haythornthwaite JA. Catastrophizing and pain in arthritis, fibromyalgia, and other rheumatic diseases. Arthritis Rheum. 2006 Apr 15; 55(2):325-32. PMID: 16583384.
    View in: PubMed
  179. Edwards RR. Age differences in the correlates of physical functioning in patients with chronic pain. J Aging Health. 2006 Feb; 18(1):56-69. PMID: 16470966.
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  180. Edwards RR, Raja S. The laterality of long-term pain following mastectomy. J Pain Symptom Manage. 2006 Feb; 31(2):98-9. PMID: 16488342.
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  181. Fillingim RB, Edwards RR. Is self-reported childhood abuse history associated with pain perception among healthy young women and men? Clin J Pain. 2005 Sep-Oct; 21(5):387-97. PMID: 16093744.
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  182. Edwards RR. Individual differences in endogenous pain modulation as a risk factor for chronic pain. Neurology. 2005 Aug 09; 65(3):437-43. PMID: 16087910.
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  183. Smith MT, Edwards RR, Stonerock GL, McCann UD. Individual variation in rapid eye movement sleep is associated with pain perception in healthy women: preliminary data. Sleep. 2005 Jul; 28(7):809-12. PMID: 16124658.
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  184. Kudel I, Edwards RR, Moric M. The role of neuroticism, pain catastrophizing and pain-related fear in vigilance to pain: a structural equations approach. A comment on Goubert et al. (2004). Pain. 2005 May; 115(1-2):214-6; author reply 216-7. PMID: 15836987.
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  185. Edwards RR, Campbell CM, Fillingim RB. Catastrophizing and experimental pain sensitivity: only in vivo reports of catastrophic cognitions correlate with pain responses. J Pain. 2005 May; 6(5):338-9. PMID: 15890636.
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  186. Edwards RR, Sarlani E, Wesselmann U, Fillingim RB. Quantitative assessment of experimental pain perception: multiple domains of clinical relevance. Pain. 2005 Apr; 114(3):315-9. PMID: 15777856.
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  187. Campbell CM, Edwards RR, Fillingim RB. Ethnic differences in responses to multiple experimental pain stimuli. Pain. 2005 Jan; 113(1-2):20-6. PMID: 15621360.
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  188. Edwards RR, Fillingim RB. Styles of pain coping predict cardiovascular function following a cold pressor test. Pain Res Manag. 2005; 10(4):219-22. PMID: 16341309.
    View in: PubMed
  189. Edwards RR, Moric M, Husfeldt B, Buvanendran A, Ivankovich O. Ethnic similarities and differences in the chronic pain experience: a comparison of african american, Hispanic, and white patients. Pain Med. 2005 Jan-Feb; 6(1):88-98. PMID: 15669954.
    View in: PubMed
  190. Edwards RR, Haythornthwaite J. Mood swings: variability in the use of the Profile of Mood States. J Pain Symptom Manage. 2004 Dec; 28(6):534. PMID: 15589077.
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  191. Edwards RR, Ness TJ, Fillingim RB. Endogenous opioids, blood pressure, and diffuse noxious inhibitory controls: a preliminary study. Percept Mot Skills. 2004 Oct; 99(2):679-87. PMID: 15560360.
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  192. Edwards RR, Haythornthwaite JA, Sullivan MJ, Fillingim RB. Catastrophizing as a mediator of sex differences in pain: differential effects for daily pain versus laboratory-induced pain. Pain. 2004 Oct; 111(3):335-41. PMID: 15363877.
    View in: PubMed
  193. Smith MT, Edwards RR, Robinson RC, Dworkin RH. Suicidal ideation, plans, and attempts in chronic pain patients: factors associated with increased risk. Pain. 2004 Sep; 111(1-2):201-8. PMID: 15327824.
    View in: PubMed
  194. Edwards RR, Fillingim RB, Maixner W, Sigurdsson A, Haythornthwaite J. Catastrophizing predicts changes in thermal pain responses after resolution of acute dental pain. J Pain. 2004 Apr; 5(3):164-70. PMID: 15106129.
    View in: PubMed
  195. Edwards RR, Doleys DM, Lowery D, Fillingim RB. Pain tolerance as a predictor of outcome following multidisciplinary treatment for chronic pain: differential effects as a function of sex. Pain. 2003 Dec; 106(3):419-26. PMID: 14659525.
    View in: PubMed
  196. Edwards RR, Ness TJ, Weigent DA, Fillingim RB. Individual differences in diffuse noxious inhibitory controls (DNIC): association with clinical variables. Pain. 2003 Dec; 106(3):427-37. PMID: 14659526.
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  197. Fillingim RB, Doleys DM, Edwards RR, Lowery D. Spousal responses are differentially associated with clinical variables in women and men with chronic pain. Clin J Pain. 2003 Jul-Aug; 19(4):217-24. PMID: 12840615.
    View in: PubMed
  198. Fillingim RB, Doleys DM, Edwards RR, Lowery D. Clinical characteristics of chronic back pain as a function of gender and oral opioid use. Spine (Phila Pa 1976). 2003 Jan 15; 28(2):143-50. PMID: 12544931.
    View in: PubMed
  199. Edwards RR, Fillingim RB, Ness TJ. Age-related differences in endogenous pain modulation: a comparison of diffuse noxious inhibitory controls in healthy older and younger adults. Pain. 2003 Jan; 101(1-2):155-65. PMID: 12507710.
    View in: PubMed
  200. Fillingim RB, Edwards RR, Doleys DM. Re: McCraken et al., A comparison of blacks and whites seeking treatment for chronic pain. Clin J Pain 2001;17:249-55. Clin J Pain. 2002 Mar-Apr; 18(2):136-7. PMID: 11882779.
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  201. Edwards RR, Fillingim RB. Effects of age on temporal summation and habituation of thermal pain: clinical relevance in healthy older and younger adults. J Pain. 2001 Dec; 2(6):307-17. PMID: 14622810.
    View in: PubMed
  202. Fillingim RB, Edwards RR. The association of hormone replacement therapy with experimental pain responses in postmenopausal women. Pain. 2001 May; 92(1-2):229-34. PMID: 11323144.
    View in: PubMed
  203. Edwards RR, Doleys DM, Fillingim RB, Lowery D. Ethnic differences in pain tolerance: clinical implications in a chronic pain population. Psychosom Med. 2001 Mar-Apr; 63(2):316-23. PMID: 11292281.
    View in: PubMed
  204. Edwards RR, Fillingim RB. Age-associated differences in responses to noxious stimuli. J Gerontol A Biol Sci Med Sci. 2001 Mar; 56(3):M180-5. PMID: 11253160.
    View in: PubMed
  205. Fillingim RB, Edwards RR, Powell T. Sex-dependent effects of reported familial pain history on recent pain complaints and experimental pain responses. Pain. 2000 May; 86(1-2):87-94. PMID: 10779665.
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  206. Fillingim RB, Edwards RR, Powell T. The relationship of sex and clinical pain to experimental pain responses. Pain. 1999 Dec; 83(3):419-25. PMID: 10568849.
    View in: PubMed
  207. Edwards RR, Fillingim RB, Yamauchi S, Sigurdsson A, Bunting S, Mohorn SG, Maixner W. Effects of gender and acute dental pain on thermal pain responses. Clin J Pain. 1999 Sep; 15(3):233-7. PMID: 10524477.
    View in: PubMed
  208. Edwards RR, Fillingim RB. Ethnic differences in thermal pain responses. Psychosom Med. 1999 May-Jun; 61(3):346-54. PMID: 10367615.
    View in: PubMed
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