Harvard Catalyst Profiles

Contact, publication, and social network information about Harvard faculty and fellows.

Wilma M. Wasco, Ph.D.

Co-Author

This page shows the publications co-authored by Wilma Wasco and Rudolph Tanzi.
Connection Strength

1.746
  1. Loss of Ataxin-1 Potentiates Alzheimer's Pathogenesis by Elevating Cerebral BACE1 Transcription. Cell. 2019 08 22; 178(5):1159-1175.e17.
    View in: PubMed
    Score: 0.217
  2. The gene defects responsible for familial Alzheimer's disease. Neurobiol Dis. 1996; 3(3):159-68.
    View in: PubMed
    Score: 0.168
  3. Genetic studies of Alzheimer's disease: lessons learned and future imperatives. Neurobiol Aging. 1994; 15 Suppl 2:S145-8.
    View in: PubMed
    Score: 0.147
  4. Search for the genes responsible for familial Alzheimer's disease. Ann N Y Acad Sci. 1993 Sep 24; 695:203-8.
    View in: PubMed
    Score: 0.144
  5. Isolation and characterization of APLP2 encoding a homologue of the Alzheimer's associated amyloid beta protein precursor. Nat Genet. 1993 Sep; 5(1):95-100.
    View in: PubMed
    Score: 0.143
  6. Silencing of the Drosophila ortholog of SOX5 in heart leads to cardiac dysfunction as detected by optical coherence tomography. Hum Mol Genet. 2013 Sep 15; 22(18):3798-806.
    View in: PubMed
    Score: 0.140
  7. The amyloid precursor-like protein (APLP) gene maps to the long arm of human chromosome 19. Genomics. 1993 Jan; 15(1):237-9.
    View in: PubMed
    Score: 0.137
  8. Genetic heterogeneity of gene defects responsible for familial Alzheimer disease. Genetica. 1993; 91(1-3):255-63.
    View in: PubMed
    Score: 0.137
  9. Reduced amyloidogenic processing of the amyloid beta-protein precursor by the small-molecule Differentiation Inducing Factor-1. Cell Signal. 2009 Apr; 21(4):567-76.
    View in: PubMed
    Score: 0.104
  10. A novel presenilin-1 mutation: increased beta-amyloid and neurofibrillary changes. Ann Neurol. 1997 Jun; 41(6):809-13.
    View in: PubMed
    Score: 0.046
  11. Endoproteolytic cleavage and proteasomal degradation of presenilin 2 in transfected cells. J Biol Chem. 1997 Apr 25; 272(17):11006-10.
    View in: PubMed
    Score: 0.046
  12. Alzheimer-associated presenilins 1 and 2: neuronal expression in brain and localization to intracellular membranes in mammalian cells. Nat Med. 1996 Feb; 2(2):224-9.
    View in: PubMed
    Score: 0.042
  13. The upstream stimulatory factor functionally interacts with the Alzheimer amyloid beta-protein precursor gene. Hum Mol Genet. 1995 Sep; 4(9):1527-33.
    View in: PubMed
    Score: 0.041
  14. The amyloid beta-protein precursor and its mammalian homologues. Evidence for a zinc-modulated heparin-binding superfamily. J Biol Chem. 1994 Oct 28; 269(43):26618-21.
    View in: PubMed
    Score: 0.039
  15. The Wilson disease gene is a copper transporting ATPase with homology to the Menkes disease gene. Nat Genet. 1993 Dec; 5(4):344-50.
    View in: PubMed
    Score: 0.036
  16. Identification of a mouse brain cDNA that encodes a protein related to the Alzheimer disease-associated amyloid beta protein precursor. Proc Natl Acad Sci U S A. 1992 Nov 15; 89(22):10758-62.
    View in: PubMed
    Score: 0.034
  17. Assessment of amyloid beta-protein precursor gene mutations in a large set of familial and sporadic Alzheimer disease cases. Am J Hum Genet. 1992 Aug; 51(2):273-82.
    View in: PubMed
    Score: 0.033
  18. Genomic structure, expression pattern, and chromosomal localization of the human calsenilin gene: no association between an exonic polymorphism and Alzheimer's disease. Neurosci Lett. 2000 Nov 24; 294(3):135-8.
    View in: PubMed
    Score: 0.015
  19. Immunohistochemical and in situ analysis of amyloid precursor-like protein-1 and amyloid precursor-like protein-2 expression in Alzheimer disease and aged control brains. Brain Res. 1998 Aug 31; 804(1):45-51.
    View in: PubMed
    Score: 0.013
  20. Phosphorylation of Alzheimer beta-amyloid precursor-like proteins. Biochemistry. 1997 Apr 15; 36(15):4643-9.
    View in: PubMed
    Score: 0.012
  21. Developmental regulation of presenilin mRNA expression parallels notch expression. J Neuropathol Exp Neurol. 1997 Jan; 56(1):40-4.
    View in: PubMed
    Score: 0.011
  22. Secreted amyloid beta-protein similar to that in the senile plaques of Alzheimer's disease is increased in vivo by the presenilin 1 and 2 and APP mutations linked to familial Alzheimer's disease. Nat Med. 1996 Aug; 2(8):864-70.
    View in: PubMed
    Score: 0.011
  23. A novel protein, amyloid precursor-like protein 2, is present in human brain, cerebrospinal fluid and conditioned media. Biochem J. 1995 Aug 15; 310 ( Pt 1):95-9.
    View in: PubMed
    Score: 0.010
  24. Selective localization of amyloid precursor-like protein 1 in the cerebral cortex postsynaptic density. Brain Res Mol Brain Res. 1995 Aug; 32(1):36-44.
    View in: PubMed
    Score: 0.010
  25. Isolation, characterization, and mapping of gene encoding dihydrolipoyl succinyltransferase (E2k) of human alpha-ketoglutarate dehydrogenase complex. Somat Cell Mol Genet. 1994 Mar; 20(2):99-105.
    View in: PubMed
    Score: 0.009
Connection Strength
The connection strength for co-authors is the sum of the scores for each of their shared publications.

Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.
Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.