Harvard Catalyst Profiles

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Wen Lu, M.D.

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Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Lu WJ, Bleeker JS. CYP2D6 and Tamoxifen: Lessons Learned. S D Med. 2017 Sep; 70(9):402-404. PMID: 28863251.
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  2. Lu WJ, Chavour S. Point-Counterpoint: Genotype-Guided Opioid Therapy. S D Med. 2017 May; 70(5):199-201. PMID: 28813750.
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  3. Lu WJ, Miller NJ. Point-Counterpoint: Genotype-Guided Warfarin Therapy. S D Med. 2017 Feb; 70(2):54-56. PMID: 28810086.
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  4. Liu J, Flockhart PJ, Lu D, Lv W, Lu WJ, Han X, Cushman M, Flockhart DA. Inhibition of cytochrome p450 enzymes by the e- and z-isomers of norendoxifen. Drug Metab Dispos. 2013 Sep; 41(9):1715-20. PMID: 23824607.
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  5. Lu WJ, Thong N, Flockhart DA. Reduced methadone clearance during aromatase inhibition. J Clin Psychopharmacol. 2012 Aug; 32(4):511-7. PMID: 22722506.
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  6. Lu WJ, Ferlito V, Xu C, Flockhart DA, Caccamese S. Enantiomers of naringenin as pleiotropic, stereoselective inhibitors of cytochrome P450 isoforms. Chirality. 2011 Nov; 23(10):891-6. PMID: 21953762.
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  7. Lu WJ, Xu C, Pei Z, Mayhoub AS, Cushman M, Flockhart DA. The tamoxifen metabolite norendoxifen is a potent and selective inhibitor of aromatase (CYP19) and a potential lead compound for novel therapeutic agents. Breast Cancer Res Treat. 2012 May; 133(1):99-109. PMID: 21814747.
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  8. Lu WJ, Desta Z, Flockhart DA. Tamoxifen metabolites as active inhibitors of aromatase in the treatment of breast cancer. Breast Cancer Res Treat. 2012 Jan; 131(2):473-81. PMID: 21390495.
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  9. Lu WJ, Bies R, Kamden LK, Desta Z, Flockhart DA. Methadone: a substrate and mechanism-based inhibitor of CYP19 (aromatase). Drug Metab Dispos. 2010 Aug; 38(8):1308-13. PMID: 20410453.
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.