Harvard Catalyst Profiles

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Michael Thorner, M.B.,B.S.


Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Bright GM, Thorner MO. A GH Secretagogue Receptor Agonist (LUM-201) Elicits Greater GH Responses than Standard GH Secretagogues in Subjects of a Pediatric GH Deficiency Trial. Horm Res Paediatr. 2022; 95(1):76-81. PMID: 35354138; PMCID: PMC9227666.
    Citations:    Fields:    Translation:Humans
  2. Bright GM, Do MT, McKew JC, Blum WF, Thorner MO. Development of a Predictive Enrichment Marker for the Oral GH Secretagogue LUM-201 in Pediatric Growth Hormone Deficiency. J Endocr Soc. 2021 Jun 01; 5(6):bvab030. PMID: 33982679; PMCID: PMC8101275.
    Citations: 6     
  3. Michael Besser G, Pfeiffer RF, Thorner MO. ANNIVERSARY REVIEW: 50 years since the discovery of bromocriptine. Eur J Endocrinol. 2018 Aug; 179(2):R69-R75. PMID: 29752299.
    Citations: 4     Fields:    Translation:HumansAnimals
  4. Gray SM, Thorner MO. Spatiotemporal Regulation of Insulin-Like Growth Factor-1 and Its Receptor in the Brain: Is There a Role for Growth Hormone? Endocrinology. 2017 02 01; 158(2):229-232. PMID: 28430923; PMCID: PMC5413082.
    Citations: 2     Fields:    Translation:Humans
  5. Yu M, Bruns DE, Jane JA, Nass RM, Oldfield EH, Vance ML, Thorner MO. Decrease of Serum IGF-I following Transsphenoidal Pituitary Surgery for Acromegaly. Clin Chem. 2017 Feb; 63(2):486-494. PMID: 27974387.
    Citations: 2     Fields:    Translation:Humans
  6. Oldfield EH, Jane JA, Thorner MO, Pledger CL, Sheehan JP, Vance ML. Correlation between GH and IGF-1 during treatment for acromegaly. J Neurosurg. 2017 Jun; 126(6):1959-1966. PMID: 27858572.
    Citations: 9     Fields:    Translation:Humans
  7. Christiansen JS, Backeljauw PF, Bidlingmaier M, Biller BM, Boguszewski MC, Casanueva FF, Chanson P, Chatelain P, Choong CS, Clemmons DR, Cohen LE, Cohen P, Frystyk J, Grimberg A, Hasegawa Y, Haymond MW, Ho K, Hoffman AR, Holly JM, Horikawa R, Höybye C, Jorgensen JO, Johannsson G, Juul A, Katznelson L, Kopchick JJ, Lee KO, Lee KW, Luo X, Melmed S, Miller BS, Misra M, Popovic V, Rosenfeld RG, Ross J, Ross RJ, Saenger P, Strasburger CJ, Thorner MO, Werner H, Yuen K. Growth Hormone Research Society perspective on the development of long-acting growth hormone preparations. Eur J Endocrinol. 2016 Jun; 174(6):C1-8. PMID: 27009113; PMCID: PMC5081743.
    Citations: 35     Fields:    Translation:Humans
  8. Allen DB, Backeljauw P, Bidlingmaier M, Biller BM, Boguszewski M, Burman P, Butler G, Chihara K, Christiansen J, Cianfarani S, Clayton P, Clemmons D, Cohen P, Darendeliler F, Deal C, Dunger D, Erfurth EM, Fuqua JS, Grimberg A, Haymond M, Higham C, Ho K, Hoffman AR, Hokken-Koelega A, Johannsson G, Juul A, Kopchick J, Lee P, Pollak M, Radovick S, Robison L, Rosenfeld R, Ross RJ, Savendahl L, Saenger P, Sorensen HT, Stochholm K, Strasburger C, Swerdlow A, Thorner M. GH safety workshop position paper: a critical appraisal of recombinant human GH therapy in children and adults. Eur J Endocrinol. 2016 02; 174(2):P1-9. PMID: 26563978; PMCID: PMC4674592.
    Citations: 71     Fields:    Translation:Humans
  9. Culver SA, Grober Y, Ornan DA, Patrie JT, Oldfield EH, Jane JA, Thorner MO. A Case for Conservative Management: Characterizing the Natural History of Radiographically Diagnosed Rathke Cleft Cysts. J Clin Endocrinol Metab. 2015 Oct; 100(10):3943-8. PMID: 26305621; PMCID: PMC5399501.
    Citations: 9     Fields:    Translation:Humans
  10. Gaylinn BD, Farhy LS, Nass R, Tong J, Thorner MO. Does des-acyl ghrelin improve glycemic control by decreasing acylated ghrelin levels? Eur J Endocrinol. 2015 Jul; 173(1):L1-2. PMID: 26026595.
    Citations:    Fields:    Translation:Humans
  11. Nass R, Nikolayev A, Liu J, Pezzoli SS, Farhy LS, Patrie J, Gaylinn BD, Heiman M, Thorner MO. The level of circulating octanoate does not predict ghrelin O-acyl transferase (GOAT)-mediated acylation of ghrelin during fasting. J Clin Endocrinol Metab. 2015 Jan; 100(1):E110-3. PMID: 25337923; PMCID: PMC4283022.
    Citations: 2     Fields:    Translation:HumansCells
  12. Nass R, Liu J, Patrie J, Pezzoli SS, Farhy LS, Gaylinn BD, Thorner MO. Four-hour infusion of hydrocortisone does not suppress the nocturnal increase of circulating acyl- or desacyl-ghrelin concentrations in healthy young adults. J Clin Endocrinol Metab. 2014 Sep; 99(9):E1696-700. PMID: 24963646; PMCID: PMC4154104.
    Citations: 2     Fields:    Translation:HumansCTClinical Trials
  13. Goldstone AP, Prechtl CG, Scholtz S, Miras AD, Chhina N, Durighel G, Deliran SS, Beckmann C, Ghatei MA, Ashby DR, Waldman AD, Gaylinn BD, Thorner MO, Frost GS, Bloom SR, Bell JD. Ghrelin mimics fasting to enhance human hedonic, orbitofrontal cortex, and hippocampal responses to food. Am J Clin Nutr. 2014 Jun; 99(6):1319-30. PMID: 24760977; PMCID: PMC6410902.
    Citations: 51     Fields:    Translation:HumansCellsCTClinical Trials
  14. Conroy R, Febres G, McMahon DJ, Thorner MO, Gaylinn BD, Conwell I, Aronne L, Korner J. Recombinant human leptin does not alter gut hormone levels after gastric bypass but may attenuate sweet cravings. Int J Endocrinol. 2014; 2014:120286. PMID: 24987413.
    Citations: 4     
  15. Nass R, Farhy LS, Liu J, Pezzoli SS, Johnson ML, Gaylinn BD, Thorner MO. Age-dependent decline in acyl-ghrelin concentrations and reduced association of acyl-ghrelin and growth hormone in healthy older adults. J Clin Endocrinol Metab. 2014 Feb; 99(2):602-8. PMID: 24285677; PMCID: PMC3913814.
    Citations: 17     Fields:    Translation:Humans
  16. Tong J, Dave N, Mugundu GM, Davis HW, Gaylinn BD, Thorner MO, Tschöp MH, D'Alessio D, Desai PB. The pharmacokinetics of acyl, des-acyl, and total ghrelin in healthy human subjects. Eur J Endocrinol. 2013 Jun; 168(6):821-8. PMID: 23482590.
    Citations: 30     Fields:    Translation:Humans
  17. Kelly BN, Haverstick DM, Lee JK, Thorner MO, Vance ML, Xin W, Bruns DE. Circulating microRNA as a biomarker of human growth hormone administration to patients. Drug Test Anal. 2014 Mar; 6(3):234-8. PMID: 23495241.
    Citations: 5     Translation:HumansPHPublic Health
  18. Müller TD, Müller A, Yi CX, Habegger KM, Meyer CW, Gaylinn BD, Finan B, Heppner K, Trivedi C, Bielohuby M, Abplanalp W, Meyer F, Piechowski CL, Pratzka J, Stemmer K, Holland J, Hembree J, Bhardwaj N, Raver C, Ottaway N, Krishna R, Sah R, Sallee FR, Woods SC, Perez-Tilve D, Bidlingmaier M, Thorner MO, Krude H, Smiley D, DiMarchi R, Hofmann S, Pfluger PT, Kleinau G, Biebermann H, Tschöp MH. The orphan receptor Gpr83 regulates systemic energy metabolism via ghrelin-dependent and ghrelin-independent mechanisms. Nat Commun. 2013; 4:1968. PMID: 23744028.
    Citations: 27     Fields:    Translation:HumansAnimalsCells
  19. Kelly BN, Haverstick DM, Vance ML, Thorner MO, Bruns DE. Quantification of growth hormone mRNA in blood. Clin Chim Acta. 2012 Dec 24; 414:206-10. PMID: 22985689.
    Citations: 1     Fields:    Translation:Humans
  20. Yi CX, Heppner KM, Kirchner H, Tong J, Bielohuby M, Gaylinn BD, Müller TD, Bartley E, Davis HW, Zhao Y, Joseph A, Kruthaupt T, Ottaway N, Kabra D, Habegger KM, Benoit SC, Bidlingmaier M, Thorner MO, Perez-Tilve D, Tschöp MH, Pfluger PT. The GOAT-ghrelin system is not essential for hypoglycemia prevention during prolonged calorie restriction. PLoS One. 2012; 7(2):e32100. PMID: 22363801.
    Citations: 24     Fields:    Translation:Animals
  21. Jane JA, Starke RM, Elzoghby MA, Reames DL, Payne SC, Thorner MO, Marshall JC, Laws ER, Vance ML. Endoscopic transsphenoidal surgery for acromegaly: remission using modern criteria, complications, and predictors of outcome. J Clin Endocrinol Metab. 2011 Sep; 96(9):2732-40. PMID: 21715544.
    Citations: 72     Fields:    Translation:Humans
  22. Nass R, Gaylinn BD, Thorner MO. The ghrelin axis in disease: potential therapeutic indications. Mol Cell Endocrinol. 2011 Jun 20; 340(1):106-10. PMID: 21356273.
    Citations: 13     Fields:    Translation:HumansAnimals
  23. Vestergaard ET, Buhl M, Gjedsted J, Madsen M, Jessen N, Nielsen S, Gaylinn BD, Liu J, Thorner MO, Moller N, Jorgensen JO. Acute peripheral metabolic effects of intraarterial ghrelin infusion in healthy young men. J Clin Endocrinol Metab. 2011 Feb; 96(2):468-77. PMID: 21084392; PMCID: PMC5393419.
    Citations: 12     Fields:    Translation:HumansCells
  24. Bush ZM, Longtine JA, Cunningham T, Schiff D, Jane JA, Vance ML, Thorner MO, Laws ER, Lopes MB. Temozolomide treatment for aggressive pituitary tumors: correlation of clinical outcome with O(6)-methylguanine methyltransferase (MGMT) promoter methylation and expression. J Clin Endocrinol Metab. 2010 Nov; 95(11):E280-90. PMID: 20668043; PMCID: PMC5393383.
    Citations: 51     Fields:    Translation:HumansCells
  25. Prudom C, Liu J, Patrie J, Gaylinn BD, Foster-Schubert KE, Cummings DE, Thorner MO, Geysen HM. Comparison of competitive radioimmunoassays and two-site sandwich assays for the measurement and interpretation of plasma ghrelin levels. J Clin Endocrinol Metab. 2010 May; 95(5):2351-8. PMID: 20194708; PMCID: PMC2869544.
    Citations: 24     Fields:    Translation:Humans
  26. Gaylinn BD, Thorner MO. Luminal influences to orchestrate gastroenterological hormone secretion: the fat, long-chain Fatty Acid, cholecystokinin, glucagon-like Peptide 1 axis. J Clin Endocrinol Metab. 2010 Feb; 95(2):503-4. PMID: 20133469.
    Citations: 4     Fields:    Translation:Humans
  27. Moller L, Norrelund H, Jessen N, Flyvbjerg A, Pedersen SB, Gaylinn BD, Liu J, Thorner MO, Moller N, Lunde Jorgensen JO. Impact of growth hormone receptor blockade on substrate metabolism during fasting in healthy subjects. J Clin Endocrinol Metab. 2009 Nov; 94(11):4524-32. PMID: 19820031; PMCID: PMC2775657.
    Citations: 17     Fields:    Translation:Humans
  28. Thorner MO. Statement by the Growth Hormone Research Society on the GH/IGF-I axis in extending health span. J Gerontol A Biol Sci Med Sci. 2009 Oct; 64(10):1039-44. PMID: 19587105.
    Citations: 22     Fields:    Translation:HumansAnimals
  29. Tham E, Liu J, Innis S, Thompson D, Gaylinn BD, Bogarin R, Haim A, Thorner MO, Chanoine JP. Acylated ghrelin concentrations are markedly decreased during pregnancy in mothers with and without gestational diabetes: relationship with cholinesterase. Am J Physiol Endocrinol Metab. 2009 May; 296(5):E1093-100. PMID: 19240252.
    Citations: 12     Fields:    Translation:HumansCells
  30. Johnson ML, Pipes L, Veldhuis PP, Farhy LS, Nass R, Thorner MO, Evans WS. AutoDecon: a robust numerical method for the quantification of pulsatile events. Methods Enzymol. 2009; 454:367-404. PMID: 19216935.
    Citations: 18     Fields:    
  31. Kim DS, Itoh E, Iida K, Thorner MO. Growth hormone increases mRNA levels of PPARdelta and Foxo1 in skeletal muscle of growth hormone deficient lit/lit mice. Endocr J. 2009; 56(1):141-7. PMID: 18997443.
    Citations: 3     Fields:    Translation:AnimalsCells
  32. Nass R, Pezzoli SS, Oliveri MC, Patrie JT, Harrell FE, Clasey JL, Heymsfield SB, Bach MA, Vance ML, Thorner MO. Effects of an oral ghrelin mimetic on body composition and clinical outcomes in healthy older adults: a randomized trial. Ann Intern Med. 2008 Nov 04; 149(9):601-11. PMID: 18981485; PMCID: PMC2757071.
    Citations: 77     Fields:    Translation:Humans
  33. Nass R, Johannsson G, Christiansen JS, Kopchick JJ, Thorner MO. The aging population--is there a role for endocrine interventions? Growth Horm IGF Res. 2009 Apr; 19(2):89-100. PMID: 18977675.
    Citations: 18     Fields:    Translation:Humans
  34. Berryman DE, Christiansen JS, Johannsson G, Thorner MO, Kopchick JJ. Role of the GH/IGF-1 axis in lifespan and healthspan: lessons from animal models. Growth Horm IGF Res. 2008 Dec; 18(6):455-71. PMID: 18710818.
    Citations: 112     Fields:    Translation:HumansAnimalsCells
  35. Jimenez C, Burman P, Abs R, Clemmons DR, Drake WM, Hutson KR, Messig M, Thorner MO, Trainer PJ, Gagel RF. Follow-up of pituitary tumor volume in patients with acromegaly treated with pegvisomant in clinical trials. Eur J Endocrinol. 2008 Nov; 159(5):517-23. PMID: 18708436.
    Citations: 15     Fields:    Translation:Humans
  36. Darzy KH, Thorner MO, Shalet SM. Cranially irradiated adult cancer survivors may have normal spontaneous GH secretion in the presence of discordant peak GH responses to stimulation tests (compensated GH deficiency). Clin Endocrinol (Oxf). 2009 Feb; 70(2):287-93. PMID: 18673465.
    Citations: 2     Fields:    Translation:Humans
  37. Chan JL, Williams CJ, Raciti P, Blakeman J, Kelesidis T, Kelesidis I, Johnson ML, Thorner MO, Mantzoros CS. Leptin does not mediate short-term fasting-induced changes in growth hormone pulsatility but increases IGF-I in leptin deficiency states. J Clin Endocrinol Metab. 2008 Jul; 93(7):2819-27. PMID: 18445667; PMCID: PMC2453057.
    Citations: 23     Fields:    Translation:Humans
  38. Liu J, Prudom CE, Nass R, Pezzoli SS, Oliveri MC, Johnson ML, Veldhuis P, Gordon DA, Howard AD, Witcher DR, Geysen HM, Gaylinn BD, Thorner MO. Novel ghrelin assays provide evidence for independent regulation of ghrelin acylation and secretion in healthy young men. J Clin Endocrinol Metab. 2008 May; 93(5):1980-7. PMID: 18349056; PMCID: PMC2386282.
    Citations: 102     Fields:    Translation:HumansCells
  39. Nass R, Farhy LS, Liu J, Prudom CE, Johnson ML, Veldhuis P, Pezzoli SS, Oliveri MC, Gaylinn BD, Geysen HM, Thorner MO. Evidence for acyl-ghrelin modulation of growth hormone release in the fed state. J Clin Endocrinol Metab. 2008 May; 93(5):1988-94. PMID: 18334589; PMCID: PMC2386275.
    Citations: 31     Fields:    Translation:HumansCells
  40. Foster-Schubert KE, Overduin J, Prudom CE, Liu J, Callahan HS, Gaylinn BD, Thorner MO, Cummings DE. Acyl and total ghrelin are suppressed strongly by ingested proteins, weakly by lipids, and biphasically by carbohydrates. J Clin Endocrinol Metab. 2008 May; 93(5):1971-9. PMID: 18198223; PMCID: PMC2386677.
    Citations: 106     Fields:    Translation:HumansCells
  41. Li G, Del Rincon JP, Jahn LA, Wu Y, Gaylinn B, Thorner MO, Liu Z. Growth hormone exerts acute vascular effects independent of systemic or muscle insulin-like growth factor I. J Clin Endocrinol Metab. 2008 Apr; 93(4):1379-85. PMID: 18182451; PMCID: PMC2291494.
    Citations: 12     Fields:    Translation:HumansCells
  42. Patil CG, Prevedello DM, Lad SP, Vance ML, Thorner MO, Katznelson L, Laws ER. Late recurrences of Cushing's disease after initial successful transsphenoidal surgery. J Clin Endocrinol Metab. 2008 Feb; 93(2):358-62. PMID: 18056770.
    Citations: 72     Fields:    Translation:Humans
  43. del Rincon JP, Iida K, Gaylinn BD, McCurdy CE, Leitner JW, Barbour LA, Kopchick JJ, Friedman JE, Draznin B, Thorner MO. Growth hormone regulation of p85alpha expression and phosphoinositide 3-kinase activity in adipose tissue: mechanism for growth hormone-mediated insulin resistance. Diabetes. 2007 Jun; 56(6):1638-46. PMID: 17363744.
    Citations: 60     Fields:    Translation:AnimalsCells
  44. Nass R, Park J, Thorner MO. Growth hormone supplementation in the elderly. Endocrinol Metab Clin North Am. 2007 Mar; 36(1):233-45. PMID: 17336743.
    Citations: 7     Fields:    Translation:Humans
  45. Darzy KH, Pezzoli SS, Thorner MO, Shalet SM. Cranial irradiation and growth hormone neurosecretory dysfunction: a critical appraisal. J Clin Endocrinol Metab. 2007 May; 92(5):1666-72. PMID: 17284618.
    Citations: 9     Fields:    Translation:Humans
  46. Darzy KH, Murray RD, Gleeson HK, Pezzoli SS, Thorner MO, Shalet SM. The impact of short-term fasting on the dynamics of 24-hour growth hormone (GH) secretion in patients with severe radiation-induced GH deficiency. J Clin Endocrinol Metab. 2006 Mar; 91(3):987-94. PMID: 16384844.
    Citations: 2     Fields:    Translation:Humans
  47. Melmed S, Casanueva F, Cavagnini F, Chanson P, Frohman LA, Gaillard R, Ghigo E, Ho K, Jaquet P, Kleinberg D, Lamberts S, Laws E, Lombardi G, Sheppard MC, Thorner M, Vance ML, Wass JA, Giustina A. Consensus statement: medical management of acromegaly. Eur J Endocrinol. 2005 Dec; 153(6):737-40. PMID: 16322377.
    Citations: 73     Fields:    Translation:Humans
  48. Iida K, Rosen CJ, Ackert-Bicknell C, Thorner MO. Genetic differences in the IGF-I gene among inbred strains of mice with different serum IGF-I levels. J Endocrinol. 2005 Sep; 186(3):481-9. PMID: 16135668.
    Citations: 5     Fields:    Translation:AnimalsCells
  49. Munafo A, Nguyen TX, Papasouliotis O, Lécuelle H, Priestley A, Thorner MO. Polyethylene glycol-conjugated growth hormone-releasing hormone is long acting and stimulates GH in healthy young and elderly subjects. Eur J Endocrinol. 2005 Aug; 153(2):249-56. PMID: 16061831.
    Citations: 1     Fields:    Translation:HumansCTClinical Trials
  50. Darzy KH, Pezzoli SS, Thorner MO, Shalet SM. The dynamics of growth hormone (GH) secretion in adult cancer survivors with severe GH deficiency acquired after brain irradiation in childhood for nonpituitary brain tumors: evidence for preserved pulsatility and diurnal variation with increased secretory disorderliness. J Clin Endocrinol Metab. 2005 May; 90(5):2794-803. PMID: 15728206.
    Citations: 8     Fields:    Translation:Humans
  51. Itoh E, Iida K, del Rincon JP, Kim DS, Thorner MO. Diurnal variation in growth hormone receptor messenger ribonucleic acid in liver and skeletal muscle of lit/+ and lit/lit mice. Endocr J. 2004 Dec; 51(6):529-35. PMID: 15644570.
    Citations: 2     Fields:    Translation:Animals
  52. Itoh E, Iida K, Kim DS, Del Rincon JP, Coschigano KT, Kopchick JJ, Thorner MO. Lack of contribution of 11betaHSD1 and glucocorticoid action to reduced muscle mass associated with reduced growth hormone action. Growth Horm IGF Res. 2004 Dec; 14(6):462-6. PMID: 15519255.
    Citations: 2     Fields:    Translation:Animals
  53. Iida K, Itoh E, Kim DS, del Rincon JP, Coschigano KT, Kopchick JJ, Thorner MO. Muscle mechano growth factor is preferentially induced by growth hormone in growth hormone-deficient lit/lit mice. J Physiol. 2004 Oct 15; 560(Pt 2):341-9. PMID: 15308683; PMCID: PMC1665252.
    Citations: 10     Fields:    Translation:Animals
  54. Nass R, Liu J, Hellmann P, Coschigano KT, Gaylinn B, Berryman DE, Kopchick JJ, Thorner MO. Chronic changes in peripheral growth hormone levels do not affect ghrelin stomach mRNA expression and serum ghrelin levels in three transgenic mouse models. J Neuroendocrinol. 2004 Aug; 16(8):669-75. PMID: 15271059.
    Citations: 5     Fields:    Translation:Animals
  55. Leung GK, Lopes MB, Thorner MO, Vance ML, Laws ER. Primary hypophysitis: a single-center experience in 16 cases. J Neurosurg. 2004 Aug; 101(2):262-71. PMID: 15309917.
    Citations: 37     Fields:    Translation:Humans
  56. Iida K, del Rincon JP, Kim DS, Itoh E, Coschigano KT, Kopchick JJ, Thorner MO. Regulation of full-length and truncated growth hormone (GH) receptor by GH in tissues of lit/lit or bovine GH transgenic mice. Am J Physiol Endocrinol Metab. 2004 Sep; 287(3):E566-73. PMID: 15165994.
    Citations: 1     Fields:    Translation:AnimalsCells
  57. Hoffman AR, Kuntze JE, Baptista J, Baum HB, Baumann GP, Biller BM, Clark RV, Cook D, Inzucchi SE, Kleinberg D, Klibanski A, Phillips LS, Ridgway EC, Robbins RJ, Schlechte J, Sharma M, Thorner MO, Vance ML. Growth hormone (GH) replacement therapy in adult-onset gh deficiency: effects on body composition in men and women in a double-blind, randomized, placebo-controlled trial. J Clin Endocrinol Metab. 2004 May; 89(5):2048-56. PMID: 15126520.
    Citations: 44     Fields:    Translation:HumansCTClinical Trials
  58. Iida K, Del Rincon JP, Kim DS, Itoh E, Nass R, Coschigano KT, Kopchick JJ, Thorner MO. Tissue-specific regulation of growth hormone (GH) receptor and insulin-like growth factor-I gene expression in the pituitary and liver of GH-deficient (lit/lit) mice and transgenic mice that overexpress bovine GH (bGH) or a bGH antagonist. Endocrinology. 2004 Apr; 145(4):1564-70. PMID: 14726438.
    Citations: 9     Fields:    Translation:Animals
  59. Clemmons DR, Chihara K, Freda PU, Ho KK, Klibanski A, Melmed S, Shalet SM, Strasburger CJ, Trainer PJ, Thorner MO. Optimizing control of acromegaly: integrating a growth hormone receptor antagonist into the treatment algorithm. J Clin Endocrinol Metab. 2003 Oct; 88(10):4759-67. PMID: 14557452.
    Citations: 15     Fields:    Translation:Humans
  60. Thorner MO. Controversy: radiotherapy for acromegaly. Clin Endocrinol (Oxf). 2003 Feb; 58(2):136-7. PMID: 12580926.
    Citations: 3     Fields:    Translation:Humans
  61. Nass R, Pezzoli SS, Chapman IM, Patrie J, Hintz RL, Hartman ML, Thorner MO. IGF-I does not affect the net increase in GH release in response to arginine. Am J Physiol Endocrinol Metab. 2002 Oct; 283(4):E702-10. PMID: 12217887.
    Citations: 3     Fields:    Translation:HumansCTClinical Trials
  62. Nass R, Thorner MO. Impact of the GH-cortisol ratio on the age-dependent changes in body composition. Growth Horm IGF Res. 2002 Jun; 12(3):147-61. PMID: 12162996.
    Citations: 15     Fields:    Translation:HumansAnimalsCells
  63. Maheshwari HG, Pezzoli SS, Rahim A, Shalet SM, Thorner MO, Baumann G. Pulsatile growth hormone secretion persists in genetic growth hormone-releasing hormone resistance. Am J Physiol Endocrinol Metab. 2002 Apr; 282(4):E943-51. PMID: 11882517.
    Citations: 9     Fields:    Translation:Humans
  64. Simpson H, Savine R, Sönksen P, Bengtsson BA, Carlsson L, Christiansen JS, Clemmons D, Cohen P, Hintz R, Ho K, Mullis P, Robinson I, Strasburger C, Tanaka T, Thorner M. Growth hormone replacement therapy for adults: into the new millennium. Growth Horm IGF Res. 2002 Feb; 12(1):1-33. PMID: 12127299.
    Citations: 20     Fields:    Translation:Humans
  65. van der Lely AJ, Hutson RK, Trainer PJ, Besser GM, Barkan AL, Katznelson L, Klibanski A, Herman-Bonert V, Melmed S, Vance ML, Freda PU, Stewart PM, Friend KE, Clemmons DR, Johannsson G, Stavrou S, Cook DM, Phillips LS, Strasburger CJ, Hackett S, Zib KA, Davis RJ, Scarlett JA, Thorner MO. Long-term treatment of acromegaly with pegvisomant, a growth hormone receptor antagonist. Lancet. 2001 Nov 24; 358(9295):1754-9. PMID: 11734231.
    Citations: 123     Fields:    Translation:HumansCTClinical Trials
  66. Clasey JL, Weltman A, Patrie J, Weltman JY, Pezzoli S, Bouchard C, Thorner MO, Hartman ML. Abdominal visceral fat and fasting insulin are important predictors of 24-hour GH release independent of age, gender, and other physiological factors. J Clin Endocrinol Metab. 2001 Aug; 86(8):3845-52. PMID: 11502822.
    Citations: 38     Fields:    Translation:Humans
  67. Horikawa R, Gaylinn BD, Lyons CE, Thorner MO. Molecular cloning of ovine and bovine growth hormone-releasing hormone receptors: the ovine receptor is C-terminally truncated. Endocrinology. 2001 Jun; 142(6):2660-8. PMID: 11356717.
    Citations: 1     Fields:    Translation:HumansAnimalsCells
  68. Peacey SR, Toogood AA, Veldhuis JD, Thorner MO, Shalet SM. The relationship between 24-hour growth hormone secretion and insulin-like growth factor I in patients with successfully treated acromegaly: impact of surgery or radiotherapy. J Clin Endocrinol Metab. 2001 Jan; 86(1):259-66. PMID: 11232010.
    Citations: 14     Fields:    Translation:Humans
  69. Murray RD, Peacey SR, Rahim A, Toogood AA, Thorner MO, Shalet SM. The diagnosis of growth hormone deficiency (GHD) in successfully treated acromegalic patients. Clin Endocrinol (Oxf). 2001 Jan; 54(1):37-44. PMID: 11167924.
    Citations: 7     Fields:    Translation:Humans
  70. Nass R, Toogood AA, Hellmann P, Bissonette E, Gaylinn B, Clark R, Thorner MO. Intracerebroventricular administration of the rat growth hormone (GH) receptor antagonist G118R stimulates GH secretion: evidence for the existence of short loop negative feedback of GH. J Neuroendocrinol. 2000 Dec; 12(12):1194-9. PMID: 11106977.
    Citations: 13     Fields:    Translation:Animals
  71. Meij BP, Lopes MB, Vance ML, Thorner MO, Laws ER. Double pituitary lesions in three patients with Cushing's disease. Pituitary. 2000 Nov; 3(3):159-68. PMID: 11383480.
    Citations: 22     Fields:    Translation:Humans
  72. Nass R, Gilrain J, Anderson S, Gaylinn B, Dalkin A, Day R, Peruggia M, Thorner MO. High plasma growth hormone (GH) levels inhibit expression of GH secretagogue receptor messenger ribonucleic acid levels in the rat pituitary. Endocrinology. 2000 Jun; 141(6):2084-9. PMID: 10830294.
    Citations: 9     Fields:    Translation:AnimalsCells
  73. Trainer PJ, Drake WM, Katznelson L, Freda PU, Herman-Bonert V, van der Lely AJ, Dimaraki EV, Stewart PM, Friend KE, Vance ML, Besser GM, Scarlett JA, Thorner MO, Parkinson C, Klibanski A, Powell JS, Barkan AL, Sheppard MC, Malsonado M, Rose DR, Clemmons DR, Johannsson G, Bengtsson BA, Stavrou S, Kleinberg DL, Cook DM, Phillips LS, Bidlingmaier M, Strasburger CJ, Hackett S, Zib K, Bennett WF, Davis RJ. Treatment of acromegaly with the growth hormone-receptor antagonist pegvisomant. N Engl J Med. 2000 Apr 20; 342(16):1171-7. PMID: 10770982.
    Citations: 154     Fields:    Translation:HumansCTClinical Trials
  74. Thorner MO. The discovery of growth hormone-releasing hormone. J Clin Endocrinol Metab. 1999 Dec; 84(12):4671-6. PMID: 10599736.
    Citations: 6     Fields:    Translation:Humans
  75. Pincus SM, Hartman ML, Roelfsema F, Thorner MO, Veldhuis JD. Hormone pulsatility discrimination via coarse and short time sampling. Am J Physiol. 1999 11; 277(5):E948-57. PMID: 10567024.
    Citations: 29     Fields:    Translation:Humans
  76. Gaylinn BD, Dealmeida VI, Lyons CE, Wu KC, Mayo KE, Thorner MO. The mutant growth hormone-releasing hormone (GHRH) receptor of the little mouse does not bind GHRH. Endocrinology. 1999 Nov; 140(11):5066-74. PMID: 10537133.
    Citations: 13     Fields:    Translation:HumansAnimalsCells
  77. Thorner MO, Strasburger CJ, Wu Z, Straume M, Bidlingmaier M, Pezzoli SS, Zib K, Scarlett JC, Bennett WF. Growth hormone (GH) receptor blockade with a PEG-modified GH (B2036-PEG) lowers serum insulin-like growth factor-I but does not acutely stimulate serum GH. J Clin Endocrinol Metab. 1999 Jun; 84(6):2098-103. PMID: 10372717.
    Citations: 16     Fields:    Translation:HumansCTClinical Trials
  78. Skinner MM, Nass R, Lopes B, Laws ER, Thorner MO. Growth hormone secretagogue receptor expression in human pituitary tumors. J Clin Endocrinol Metab. 1998 Dec; 83(12):4314-20. PMID: 9851770.
    Citations: 6     Fields:    Translation:Humans
  79. Chapman IM, Hartman ML, Pieper KS, Skiles EH, Pezzoli SS, Hintz RL, Thorner MO. Recovery of growth hormone release from suppression by exogenous insulin-like growth factor I (IGF-I): evidence for a suppressive action of free rather than bound IGF-I. J Clin Endocrinol Metab. 1998 Aug; 83(8):2836-42. PMID: 9709956.
    Citations: 8     Fields:    Translation:HumansCTClinical Trials
  80. Thorner MO. Citation for the 1998 Monsanto Clinical Investigator Award of the Endocrine Society to Dr. Cyril Y. Bowers. Endocr Rev. 1998 Aug; 19(4):511. PMID: 9841200.
    Citations:    Fields:    Translation:HumansAnimals
  81. Iranmanesh A, South S, Liem AY, Clemmons D, Thorner MO, Weltman A, Veldhuis JD. Unequal impact of age, percentage body fat, and serum testosterone concentrations on the somatotrophic, IGF-I, and IGF-binding protein responses to a three-day intravenous growth hormone-releasing hormone pulsatile infusion in men. Eur J Endocrinol. 1998 Jul; 139(1):59-71. PMID: 9703380.
    Citations: 13     Fields:    Translation:HumansCTClinical Trials
  82. Gill MS, Toogood AA, O'Neill PA, Thorner MO, Shalet SM, Clayton PE. Urinary growth hormone (GH), insulin-like growth factor I (IGF-I), and IGF-binding protein-3 measurements in the diagnosis of adult GH deficiency. J Clin Endocrinol Metab. 1998 Jul; 83(7):2562-5. PMID: 9661643.
    Citations: 2     Fields:    Translation:Humans
  83. Toogood AA, Jones J, O'Neill PA, Thorner MO, Shalet SM. The diagnosis of severe growth hormone deficiency in elderly patients with hypothalamic-pituitary disease. Clin Endocrinol (Oxf). 1998 May; 48(5):569-76. PMID: 9666868.
    Citations: 6     Fields:    Translation:Humans
  84. Moreno-Reyes R, Kerkhofs M, L'Hermite-Balériaux M, Thorner MO, Van Cauter E, Copinschi G. Evidence against a role for the growth hormone-releasing peptide axis in human slow-wave sleep regulation. Am J Physiol. 1998 05; 274(5):E779-84. PMID: 9612233.
    Citations: 1     Fields:    Translation:HumansCTClinical Trials
  85. Chapman IM, Pescovitz OH, Murphy G, Treep T, Cerchio KA, Krupa D, Gertz B, Polvino WJ, Skiles EH, Pezzoli SS, Thorner MO. Oral administration of growth hormone (GH) releasing peptide-mimetic MK-677 stimulates the GH/insulin-like growth factor-I axis in selected GH-deficient adults. J Clin Endocrinol Metab. 1997 Oct; 82(10):3455-63. PMID: 9329386.
    Citations: 12     Fields:    Translation:HumansCTClinical Trials
  86. Thapar K, Kovacs K, Stefaneanu L, Scheithauer B, Killinger DW, Lioyd RV, Smyth HS, Barr A, Thorner MO, Gaylinn B, Laws ER. Overexpression of the growth-hormone-releasing hormone gene in acromegaly-associated pituitary tumors. An event associated with neoplastic progression and aggressive behavior. Am J Pathol. 1997 Sep; 151(3):769-84. PMID: 9284826; PMCID: PMC1857857.
    Citations: 21     Fields:    Translation:Humans
  87. Chapman IM, Hartman ML, Pezzoli SS, Harrell FE, Hintz RL, Alberti KG, Thorner MO. Effect of aging on the sensitivity of growth hormone secretion to insulin-like growth factor-I negative feedback. J Clin Endocrinol Metab. 1997 Sep; 82(9):2996-3004. PMID: 9284733.
    Citations: 12     Fields:    Translation:Humans
  88. Gill MS, Toogood AA, O'Neill PA, Adams JE, Thorner MO, Shalet SM, Clayton PE. Relationship between growth hormone (GH) status, serum leptin and body composition in healthy and GH deficient elderly subjects. Clin Endocrinol (Oxf). 1997 Aug; 47(2):161-7. PMID: 9302388.
    Citations: 9     Fields:    Translation:Humans
  89. Toogood AA, Nass RM, Pezzoli SS, O'Neill PA, Thorner MO, Shalet SM. Preservation of growth hormone pulsatility despite pituitary pathology, surgery, and irradiation. J Clin Endocrinol Metab. 1997 Jul; 82(7):2215-21. PMID: 9215297.
    Citations: 4     Fields:    Translation:Humans
  90. Lopes MB, Gaylinn BD, Thorner MO, Stoler MH. Growth hormone-releasing hormone receptor mRNA in acromegalic pituitary tumors. Am J Pathol. 1997 Jun; 150(6):1885-91. PMID: 9176381; PMCID: PMC1858316.
    Citations: 6     Fields:    Translation:Humans
  91. Kirk SE, Gertz BJ, Schneider SH, Hartman ML, Pezzoli SS, Wittreich JM, Krupa DA, Seibold JR, Thorner MO. Effect of obesity and feeding on the growth hormone (GH) response to the GH secretagogue L-692,429 in young men. J Clin Endocrinol Metab. 1997 Apr; 82(4):1154-9. PMID: 9100588.
    Citations: 2     Fields:    Translation:HumansCTClinical Trials
  92. Molitch ME, Thorner MO, Wilson C. Management of prolactinomas. J Clin Endocrinol Metab. 1997 Apr; 82(4):996-1000. PMID: 9100563.
    Citations: 16     Fields:    Translation:Humans
  93. Thorner MO, Chapman IM, Gaylinn BD, Pezzoli SS, Hartman ML. Growth hormone-releasing hormone and growth hormone-releasing peptide as therapeutic agents to enhance growth hormone secretion in disease and aging. Recent Prog Horm Res. 1997; 52:215-44; discussion 244-6. PMID: 9238854.
    Citations: 7     Fields:    Translation:Humans
  94. Thorner MO. Theodore R. Woodward Award. Age-related decline in growth hormone secretion: clinical significance and potential reversibility. Trans Am Clin Climatol Assoc. 1997; 108:99-105; discussion 105-8. PMID: 9108670; PMCID: PMC2376584.
    Citations:    Fields:    Translation:Humans
  95. Chapman IM, Bach MA, Van Cauter E, Farmer M, Krupa D, Taylor AM, Schilling LM, Cole KY, Skiles EH, Pezzoli SS, Hartman ML, Veldhuis JD, Gormley GJ, Thorner MO. Stimulation of the growth hormone (GH)-insulin-like growth factor I axis by daily oral administration of a GH secretogogue (MK-677) in healthy elderly subjects. J Clin Endocrinol Metab. 1996 Dec; 81(12):4249-57. PMID: 8954023.
    Citations: 39     Fields:    Translation:HumansCTClinical Trials
  96. Chapman IM, Hartman ML, Pezzoli SS, Thorner MO. Enhancement of pulsatile growth hormone secretion by continuous infusion of a growth hormone-releasing peptide mimetic, L-692,429, in older adults--a clinical research center study. J Clin Endocrinol Metab. 1996 Aug; 81(8):2874-80. PMID: 8768844.
    Citations: 5     Fields:    Translation:Humans
  97. Copinschi G, Van Onderbergen A, L'Hermite-Balériaux M, Mendel CM, Caufriez A, Leproult R, Bolognese JA, De Smet M, Thorner MO, Van Cauter E. Effects of a 7-day treatment with a novel, orally active, growth hormone (GH) secretagogue, MK-677, on 24-hour GH profiles, insulin-like growth factor I, and adrenocortical function in normal young men. J Clin Endocrinol Metab. 1996 Aug; 81(8):2776-82. PMID: 8768828.
    Citations: 3     Fields:    Translation:HumansCTClinical Trials
  98. Laws ER, Thorner MO, Vance ML. Bromocriptine therapy for prolactin-secreting pituitary adenomas. Neurosurg Focus. 1996 Jul 15; 1(1):e4; discussion 1p following e6. PMID: 15095998.
    Citations: 2     Fields:    
  99. Hartman ML, Pezzoli SS, Hellmann PJ, Suratt PM, Thorner MO. Pulsatile growth hormone secretion in older persons is enhanced by fasting without relationship to sleep stages. J Clin Endocrinol Metab. 1996 Jul; 81(7):2694-701. PMID: 8675598.
    Citations: 5     Fields:    Translation:Humans
  100. Friend KE, Hartman ML, Pezzoli SS, Clasey JL, Thorner MO. Both oral and transdermal estrogen increase growth hormone release in postmenopausal women--a clinical research center study. J Clin Endocrinol Metab. 1996 Jun; 81(6):2250-6. PMID: 8964860.
    Citations: 35     Fields:    Translation:Humans
  101. Thorner M, Rochiccioli P, Colle M, Lanes R, Grunt J, Galazka A, Landy H, Eengrand P, Shah S. Once daily subcutaneous growth hormone-releasing hormone therapy accelerates growth in growth hormone-deficient children during the first year of therapy. Geref International Study Group. J Clin Endocrinol Metab. 1996 Mar; 81(3):1189-96. PMID: 8772599.
    Citations: 3     Fields:    Translation:HumansCTClinical Trials
  102. Bergendahl M, Vance ML, Iranmanesh A, Thorner MO, Veldhuis JD. Fasting as a metabolic stress paradigm selectively amplifies cortisol secretory burst mass and delays the time of maximal nyctohemeral cortisol concentrations in healthy men. J Clin Endocrinol Metab. 1996 Feb; 81(2):692-9. PMID: 8636290.
    Citations: 16     Fields:    Translation:HumansCTClinical Trials
  103. Melmed S, Ho K, Klibanski A, Reichlin S, Thorner M. Clinical review 75: Recent advances in pathogenesis, diagnosis, and management of acromegaly. J Clin Endocrinol Metab. 1995 Dec; 80(12):3395-402. PMID: 8530571.
    Citations: 37     Fields:    Translation:Humans
  104. Thorner MO, Bengtsson BA, Ho KY, Albertsson-Wikland K, Christiansen JS, Faglia G, Irie M, Isaksson O, Jörgensen JO, Ranke M, et al. The diagnosis of growth hormone deficiency (GHD) in adults. J Clin Endocrinol Metab. 1995 Oct; 80(10):3097-8. PMID: 7559905.
    Citations: 10     Fields:    Translation:Humans
  105. Thorner MO, Hartman ML, Vance ML, Pezzoli SS, Ampleford EJ. Neuroendocrine regulation of growth hormone secretion. Neurosci Biobehav Rev. 1995; 19(3):465-8. PMID: 7566747.
    Citations: 1     Fields:    Translation:HumansAnimals
  106. Silva CM, Lu H, Weber MJ, Thorner MO. Differential tyrosine phosphorylation of JAK1, JAK2, and STAT1 by growth hormone and interferon-gamma in IM-9 cells. J Biol Chem. 1994 Nov 04; 269(44):27532-9. PMID: 7525556.
    Citations: 6     Fields:    Translation:HumansCells
  107. Aloi JA, Gertz BJ, Hartman ML, Huhn WC, Pezzoli SS, Wittreich JM, Krupa DA, Thorner MO. Neuroendocrine responses to a novel growth hormone secretagogue, L-692,429, in healthy older subjects. J Clin Endocrinol Metab. 1994 Oct; 79(4):943-9. PMID: 7962302.
    Citations: 11     Fields:    Translation:HumansCTClinical Trials
  108. Clayton PE, Day RN, Silva CM, Hellmann P, Day KH, Thorner MO. Growth hormone induces tyrosine phosphorylation but does not alter insulin-like growth factor-I gene expression in human IM9 lymphocytes. J Mol Endocrinol. 1994 Oct; 13(2):127-36. PMID: 7848524.
    Citations: 1     Fields:    Translation:HumansCells
  109. Hartman ML, Pincus SM, Johnson ML, Matthews DH, Faunt LM, Vance ML, Thorner MO, Veldhuis JD. Enhanced basal and disorderly growth hormone secretion distinguish acromegalic from normal pulsatile growth hormone release. J Clin Invest. 1994 Sep; 94(3):1277-88. PMID: 8083369; PMCID: PMC295213.
    Citations: 39     Fields:    Translation:Humans
  110. Gaylinn BD, Lyons CE, Zysk JR, Clarke IJ, Thorner MO. Photoaffinity cross-linking to the pituitary receptor for growth hormone-releasing factor. Endocrinology. 1994 Sep; 135(3):950-5. PMID: 8070391.
    Citations: 1     Fields:    Translation:AnimalsCells
  111. Chapman IM, Hartman ML, Straume M, Johnson ML, Veldhuis JD, Thorner MO. Enhanced sensitivity growth hormone (GH) chemiluminescence assay reveals lower postglucose nadir GH concentrations in men than women. J Clin Endocrinol Metab. 1994 Jun; 78(6):1312-9. PMID: 8200931.
    Citations: 21     Fields:    Translation:Humans
  112. Gaylinn BD, von Kap-Herr C, Golden WL, Thorner MO. Assignment of the human growth hormone-releasing hormone receptor gene (GHRHR) to 7p14 by in situ hybridization. Genomics. 1994 Jan 01; 19(1):193-5. PMID: 8188233.
    Citations: 1     Fields:    Translation:HumansAnimalsCells
  113. Silva CM, Day RN, Weber MJ, Thorner MO. Human growth hormone (GH) receptor is characterized as the 134-kilodalton tyrosine-phosphorylated protein activated by GH treatment in IM-9 cells. Endocrinology. 1993 Nov; 133(5):2307-12. PMID: 7691587.
    Citations: 3     Fields:    Translation:HumansCells
  114. Hartman ML, Clayton PE, Johnson ML, Celniker A, Perlman AJ, Alberti KG, Thorner MO. A low dose euglycemic infusion of recombinant human insulin-like growth factor I rapidly suppresses fasting-enhanced pulsatile growth hormone secretion in humans. J Clin Invest. 1993 Jun; 91(6):2453-62. PMID: 8514857; PMCID: PMC443305.
    Citations: 22     Fields:    Translation:Humans
  115. Huhn WC, Hartman ML, Pezzoli SS, Thorner MO. Twenty-four-hour growth hormone (GH)-releasing peptide (GHRP) infusion enhances pulsatile GH secretion and specifically attenuates the response to a subsequent GHRP bolus. J Clin Endocrinol Metab. 1993 May; 76(5):1202-8. PMID: 8496311.
    Citations: 9     Fields:    Translation:Humans
  116. Kerkhofs M, Van Cauter E, Van Onderbergen A, Caufriez A, Thorner MO, Copinschi G. Sleep-promoting effects of growth hormone-releasing hormone in normal men. Am J Physiol. 1993 Apr; 264(4 Pt 1):E594-8. PMID: 8476038.
    Citations: 18     Fields:    Translation:Humans
  117. Veldhuis JD, Iranmanesh A, Evans WS, Lizarralde G, Thorner MO, Vance ML. Amplitude suppression of the pulsatile mode of immunoradiometric luteinizing hormone release in fasting-induced hypoandrogenemia in normal men. J Clin Endocrinol Metab. 1993 Mar; 76(3):587-93. PMID: 8445014.
    Citations: 15     Fields:    Translation:Humans
  118. Gaylinn BD, Harrison JK, Zysk JR, Lyons CE, Lynch KR, Thorner MO. Molecular cloning and expression of a human anterior pituitary receptor for growth hormone-releasing hormone. Mol Endocrinol. 1993 Jan; 7(1):77-84. PMID: 7680413.
    Citations: 28     Fields:    Translation:HumansAnimalsCells
  119. Van Cauter E, Kerkhofs M, Caufriez A, Van Onderbergen A, Thorner MO, Copinschi G. A quantitative estimation of growth hormone secretion in normal man: reproducibility and relation to sleep and time of day. J Clin Endocrinol Metab. 1992 Jun; 74(6):1441-50. PMID: 1592892.
    Citations: 31     Fields:    Translation:Humans
  120. Van Cauter E, Caufriez A, Kerkhofs M, Van Onderbergen A, Thorner MO, Copinschi G. Sleep, awakenings, and insulin-like growth factor-I modulate the growth hormone (GH) secretory response to GH-releasing hormone. J Clin Endocrinol Metab. 1992 Jun; 74(6):1451-9. PMID: 1592893.
    Citations: 11     Fields:    Translation:Humans
  121. Hartman ML, Farello G, Pezzoli SS, Thorner MO. Oral administration of growth hormone (GH)-releasing peptide stimulates GH secretion in normal men. J Clin Endocrinol Metab. 1992 Jun; 74(6):1378-84. PMID: 1592884.
    Citations: 7     Fields:    Translation:HumansCTClinical Trials
  122. Hartman ML, Veldhuis JD, Johnson ML, Lee MM, Alberti KG, Samojlik E, Thorner MO. Augmented growth hormone (GH) secretory burst frequency and amplitude mediate enhanced GH secretion during a two-day fast in normal men. J Clin Endocrinol Metab. 1992 Apr; 74(4):757-65. PMID: 1548337.
    Citations: 33     Fields:    Translation:Humans
  123. Goth MI, Lyons CE, Canny BJ, Thorner MO. Pituitary adenylate cyclase activating polypeptide, growth hormone (GH)-releasing peptide and GH-releasing hormone stimulate GH release through distinct pituitary receptors. Endocrinology. 1992 Feb; 130(2):939-44. PMID: 1346381.
    Citations: 28     Fields:    Translation:AnimalsCells
  124. Press M, Caprio S, Tamborlane WV, Bhushan R, Thorner M, Vale W, Rivier J, Sherwin RS. Pituitary response to growth hormone-releasing hormone in IDDM. Abnormal responses to insulin and hyperglycemia. Diabetes. 1992 Jan; 41(1):17-21. PMID: 1727733.
    Citations: 5     Fields:    Translation:Humans
  125. Vance ML, Hartman ML, Thorner MO. Growth hormone and nutrition. Horm Res. 1992; 38 Suppl 1:85-8. PMID: 1295819.
    Citations: 7     Fields:    Translation:HumansCells
  126. Painson JC, Thorner MO, Krieg RJ, Tannenbaum GS. Short-term adult exposure to estradiol feminizes the male pattern of spontaneous and growth hormone-releasing factor-stimulated growth hormone secretion in the rat. Endocrinology. 1992 Jan; 130(1):511-9. PMID: 1345780.
    Citations: 11     Fields:    Translation:Animals
  127. Barth RJ, Constant RB, Parker MW, Mueller GL, Kovacs K, Thorner MO. Preoperative diagnosis of acromegaly by growth hormone-releasing factor radioimmunoassay. Mil Med. 1991 Jul; 156(7):375-8. PMID: 1922854.
    Citations: 2     Fields:    Translation:Humans
  128. DeBell WK, Pezzoli SS, Thorner MO. Growth hormone (GH) secretion during continuous infusion of GH-releasing peptide: partial response attenuation. J Clin Endocrinol Metab. 1991 Jun; 72(6):1312-6. PMID: 2026752.
    Citations: 8     Fields:    Translation:Humans
  129. Leong DA, Thorner MO. A potential code of luteinizing hormone-releasing hormone-induced calcium ion responses in the regulation of luteinizing hormone secretion among individual gonadotropes. J Biol Chem. 1991 May 15; 266(14):9016-22. PMID: 2026609.
    Citations: 13     Fields:    Translation:AnimalsCells
  130. Holl RW, Hartman ML, Veldhuis JD, Taylor WM, Thorner MO. Thirty-second sampling of plasma growth hormone in man: correlation with sleep stages. J Clin Endocrinol Metab. 1991 Apr; 72(4):854-61. PMID: 2005213.
    Citations: 24     Fields:    Translation:Humans
  131. Hartman ML, Faria AC, Vance ML, Johnson ML, Thorner MO, Veldhuis JD. Temporal structure of in vivo growth hormone secretory events in humans. Am J Physiol. 1991 Jan; 260(1 Pt 1):E101-10. PMID: 1987784.
    Citations: 35     Fields:    Translation:Humans
  132. Thorner MO, Vance ML, Hartman ML, Holl RW, Evans WS, Veldhuis JD, Van Cauter E, Copinschi G, Bowers CY. Physiological role of somatostatin on growth hormone regulation in humans. Metabolism. 1990 Sep; 39(9 Suppl 2):40-2. PMID: 1976218.
    Citations: 11     Fields:    Translation:HumansCells
  133. Baumann G, Vance ML, Shaw MA, Thorner MO. Plasma transport of human growth hormone in vivo. J Clin Endocrinol Metab. 1990 Aug; 71(2):470-3. PMID: 2380341.
    Citations: 1     Fields:    Translation:Humans
  134. Hartman ML, Veldhuis JD, Vance ML, Faria AC, Furlanetto RW, Thorner MO. Somatotropin pulse frequency and basal concentrations are increased in acromegaly and are reduced by successful therapy. J Clin Endocrinol Metab. 1990 May; 70(5):1375-84. PMID: 2335577.
    Citations: 22     Fields:    Translation:Humans
  135. Bowers CY, Reynolds GA, Durham D, Barrera CM, Pezzoli SS, Thorner MO. Growth hormone (GH)-releasing peptide stimulates GH release in normal men and acts synergistically with GH-releasing hormone. J Clin Endocrinol Metab. 1990 Apr; 70(4):975-82. PMID: 2108187.
    Citations: 33     Fields:    Translation:HumansCTClinical Trials
  136. Martha PM, Blizzard RM, Thorner MO, Rogol AD. Atenolol enhances nocturnal growth hormone (GH) release in GH-deficient children during long term GH-releasing hormone therapy. J Clin Endocrinol Metab. 1990 Jan; 70(1):56-61. PMID: 2104629.
    Citations: 2     Fields:    Translation:Humans
  137. Thorner MO, Vance ML, Rogol AD, Blizzard RM, Veldhuis JD, Cauter EV, Copinschi G, Bowers CY. Growth hormone-releasing hormone and growth hormone-releasing peptide as potential therapeutic modalities. Acta Paediatr Scand Suppl. 1990; 367:29-32. PMID: 1977276.
    Citations: 1     Fields:    Translation:Humans
  138. Nemeroff CB, Krishnan KR, Belkin BM, Ritchie JC, Clark C, Vale WW, Rivier JE, Thorner MO. Growth hormone response to growth hormone releasing factor in Alzheimer's disease. Neuroendocrinology. 1989 Dec; 50(6):663-6. PMID: 2515465.
    Citations: 4     Fields:    Translation:Humans
  139. Vance ML, Thorner MO. Fasting alters pulsatile and rhythmic cortisol release in normal man. J Clin Endocrinol Metab. 1989 Jun; 68(6):1013-8. PMID: 2723024.
    Citations: 12