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Michael Thorner, M.B.,B.S.

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Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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  1. Michael Besser G, Pfeiffer RF, Thorner MO. ANNIVERSARY REVIEW: 50 years since the discovery of bromocriptine. Eur J Endocrinol. 2018 Aug; 179(2):R69-R75. PMID: 29752299.
    Citations:    
  2. Gray SM, Thorner MO. Spatiotemporal Regulation of Insulin-Like Growth Factor-1 and Its Receptor in the Brain: Is There a Role for Growth Hormone? Endocrinology. 2017 02 01; 158(2):229-232. PMID: 28430923.
    Citations:    
  3. Yu M, Bruns DE, Jane JA, Nass RM, Oldfield EH, Vance ML, Thorner MO. Decrease of Serum IGF-I following Transsphenoidal Pituitary Surgery for Acromegaly. Clin Chem. 2017 Feb; 63(2):486-494. PMID: 27974387.
    Citations:    
  4. Oldfield EH, Jane JA, Thorner MO, Pledger CL, Sheehan JP, Vance ML. Correlation between GH and IGF-1 during treatment for acromegaly. J Neurosurg. 2017 Jun; 126(6):1959-1966. PMID: 27858572.
    Citations:    
  5. Christiansen JS, Backeljauw PF, Bidlingmaier M, Biller BM, Boguszewski MC, Casanueva FF, Chanson P, Chatelain P, Choong CS, Clemmons DR, Cohen LE, Cohen P, Frystyk J, Grimberg A, Hasegawa Y, Haymond MW, Ho K, Hoffman AR, Holly JM, Horikawa R, Höybye C, Jorgensen JO, Johannsson G, Juul A, Katznelson L, Kopchick JJ, Lee KO, Lee KW, Luo X, Melmed S, Miller BS, Misra M, Popovic V, Rosenfeld RG, Ross J, Ross RJ, Saenger P, Strasburger CJ, Thorner MO, Werner H, Yuen K. Growth Hormone Research Society perspective on the development of long-acting growth hormone preparations. Eur J Endocrinol. 2016 Jun; 174(6):C1-8. PMID: 27009113.
    Citations: 6     Fields:    Translation:Humans
  6. Allen DB, Backeljauw P, Bidlingmaier M, Biller BM, Boguszewski M, Burman P, Butler G, Chihara K, Christiansen J, Cianfarani S, Clayton P, Clemmons D, Cohen P, Darendeliler F, Deal C, Dunger D, Erfurth EM, Fuqua JS, Grimberg A, Haymond M, Higham C, Ho K, Hoffman AR, Hokken-Koelega A, Johannsson G, Juul A, Kopchick J, Lee P, Pollak M, Radovick S, Robison L, Rosenfeld R, Ross RJ, Savendahl L, Saenger P, Sorensen HT, Stochholm K, Strasburger C, Swerdlow A, Thorner M. GH safety workshop position paper: a critical appraisal of recombinant human GH therapy in children and adults. Eur J Endocrinol. 2016 02; 174(2):P1-9. PMID: 26563978.
    Citations: 22     Fields:    Translation:Humans
  7. Culver SA, Grober Y, Ornan DA, Patrie JT, Oldfield EH, Jane JA, Thorner MO. A Case for Conservative Management: Characterizing the Natural History of Radiographically Diagnosed Rathke Cleft Cysts. J Clin Endocrinol Metab. 2015 Oct; 100(10):3943-8. PMID: 26305621.
    Citations:    
  8. Gaylinn BD, Farhy LS, Nass R, Tong J, Thorner MO. Does des-acyl ghrelin improve glycemic control by decreasing acylated ghrelin levels? Eur J Endocrinol. 2015 Jul; 173(1):L1-2. PMID: 26026595.
    Citations:    
  9. Nass R, Nikolayev A, Liu J, Pezzoli SS, Farhy LS, Patrie J, Gaylinn BD, Heiman M, Thorner MO. The level of circulating octanoate does not predict ghrelin O-acyl transferase (GOAT)-mediated acylation of ghrelin during fasting. J Clin Endocrinol Metab. 2015 Jan; 100(1):E110-3. PMID: 25337923.
    Citations:    
  10. Nass R, Liu J, Patrie J, Pezzoli SS, Farhy LS, Gaylinn BD, Thorner MO. Four-hour infusion of hydrocortisone does not suppress the nocturnal increase of circulating acyl- or desacyl-ghrelin concentrations in healthy young adults. J Clin Endocrinol Metab. 2014 Sep; 99(9):E1696-700. PMID: 24963646.
    Citations:    
  11. Goldstone AP, Prechtl CG, Scholtz S, Miras AD, Chhina N, Durighel G, Deliran SS, Beckmann C, Ghatei MA, Ashby DR, Waldman AD, Gaylinn BD, Thorner MO, Frost GS, Bloom SR, Bell JD. Ghrelin mimics fasting to enhance human hedonic, orbitofrontal cortex, and hippocampal responses to food. Am J Clin Nutr. 2014 Jun; 99(6):1319-30. PMID: 24760977.
    Citations:    
  12. Conroy R, Febres G, McMahon DJ, Thorner MO, Gaylinn BD, Conwell I, Aronne L, Korner J. Recombinant human leptin does not alter gut hormone levels after gastric bypass but may attenuate sweet cravings. Int J Endocrinol. 2014; 2014:120286. PMID: 24987413.
    Citations:    
  13. Nass R, Farhy LS, Liu J, Pezzoli SS, Johnson ML, Gaylinn BD, Thorner MO. Age-dependent decline in acyl-ghrelin concentrations and reduced association of acyl-ghrelin and growth hormone in healthy older adults. J Clin Endocrinol Metab. 2014 Feb; 99(2):602-8. PMID: 24285677.
    Citations:    
  14. Tong J, Dave N, Mugundu GM, Davis HW, Gaylinn BD, Thorner MO, Tschöp MH, D'Alessio D, Desai PB. The pharmacokinetics of acyl, des-acyl, and total ghrelin in healthy human subjects. Eur J Endocrinol. 2013 Jun; 168(6):821-8. PMID: 23482590.
    Citations:    
  15. Kelly BN, Haverstick DM, Lee JK, Thorner MO, Vance ML, Xin W, Bruns DE. Circulating microRNA as a biomarker of human growth hormone administration to patients. Drug Test Anal. 2014 Mar; 6(3):234-8. PMID: 23495241.
    Citations:    
  16. Müller TD, Müller A, Yi CX, Habegger KM, Meyer CW, Gaylinn BD, Finan B, Heppner K, Trivedi C, Bielohuby M, Abplanalp W, Meyer F, Piechowski CL, Pratzka J, Stemmer K, Holland J, Hembree J, Bhardwaj N, Raver C, Ottaway N, Krishna R, Sah R, Sallee FR, Woods SC, Perez-Tilve D, Bidlingmaier M, Thorner MO, Krude H, Smiley D, DiMarchi R, Hofmann S, Pfluger PT, Kleinau G, Biebermann H, Tschöp MH. The orphan receptor Gpr83 regulates systemic energy metabolism via ghrelin-dependent and ghrelin-independent mechanisms. Nat Commun. 2013; 4:1968. PMID: 23744028.
    Citations:    
  17. Kelly BN, Haverstick DM, Vance ML, Thorner MO, Bruns DE. Quantification of growth hormone mRNA in blood. Clin Chim Acta. 2012 Dec 24; 414:206-10. PMID: 22985689.
    Citations:    
  18. Yi CX, Heppner KM, Kirchner H, Tong J, Bielohuby M, Gaylinn BD, Müller TD, Bartley E, Davis HW, Zhao Y, Joseph A, Kruthaupt T, Ottaway N, Kabra D, Habegger KM, Benoit SC, Bidlingmaier M, Thorner MO, Perez-Tilve D, Tschöp MH, Pfluger PT. The GOAT-ghrelin system is not essential for hypoglycemia prevention during prolonged calorie restriction. PLoS One. 2012; 7(2):e32100. PMID: 22363801.
    Citations:    
  19. Jane JA, Starke RM, Elzoghby MA, Reames DL, Payne SC, Thorner MO, Marshall JC, Laws ER, Vance ML. Endoscopic transsphenoidal surgery for acromegaly: remission using modern criteria, complications, and predictors of outcome. J Clin Endocrinol Metab. 2011 Sep; 96(9):2732-40. PMID: 21715544.
    Citations: 42     Fields:    Translation:Humans
  20. Nass R, Gaylinn BD, Thorner MO. The ghrelin axis in disease: potential therapeutic indications. Mol Cell Endocrinol. 2011 Jun 20; 340(1):106-10. PMID: 21356273.
    Citations:    
  21. Vestergaard ET, Buhl M, Gjedsted J, Madsen M, Jessen N, Nielsen S, Gaylinn BD, Liu J, Thorner MO, Moller N, Jorgensen JO. Acute peripheral metabolic effects of intraarterial ghrelin infusion in healthy young men. J Clin Endocrinol Metab. 2011 Feb; 96(2):468-77. PMID: 21084392.
    Citations:    
  22. Bush ZM, Longtine JA, Cunningham T, Schiff D, Jane JA, Vance ML, Thorner MO, Laws ER, Lopes MB. Temozolomide treatment for aggressive pituitary tumors: correlation of clinical outcome with O(6)-methylguanine methyltransferase (MGMT) promoter methylation and expression. J Clin Endocrinol Metab. 2010 Nov; 95(11):E280-90. PMID: 20668043.
    Citations: 43     Fields:    Translation:HumansCells
  23. Prudom C, Liu J, Patrie J, Gaylinn BD, Foster-Schubert KE, Cummings DE, Thorner MO, Geysen HM. Comparison of competitive radioimmunoassays and two-site sandwich assays for the measurement and interpretation of plasma ghrelin levels. J Clin Endocrinol Metab. 2010 May; 95(5):2351-8. PMID: 20194708.
    Citations:    
  24. Gaylinn BD, Thorner MO. Luminal influences to orchestrate gastroenterological hormone secretion: the fat, long-chain Fatty Acid, cholecystokinin, glucagon-like Peptide 1 axis. J Clin Endocrinol Metab. 2010 Feb; 95(2):503-4. PMID: 20133469.
    Citations:    
  25. Moller L, Norrelund H, Jessen N, Flyvbjerg A, Pedersen SB, Gaylinn BD, Liu J, Thorner MO, Moller N, Lunde Jorgensen JO. Impact of growth hormone receptor blockade on substrate metabolism during fasting in healthy subjects. J Clin Endocrinol Metab. 2009 Nov; 94(11):4524-32. PMID: 19820031.
    Citations:    
  26. Thorner MO. Statement by the Growth Hormone Research Society on the GH/IGF-I axis in extending health span. J Gerontol A Biol Sci Med Sci. 2009 Oct; 64(10):1039-44. PMID: 19587105.
    Citations:    
  27. Tham E, Liu J, Innis S, Thompson D, Gaylinn BD, Bogarin R, Haim A, Thorner MO, Chanoine JP. Acylated ghrelin concentrations are markedly decreased during pregnancy in mothers with and without gestational diabetes: relationship with cholinesterase. Am J Physiol Endocrinol Metab. 2009 May; 296(5):E1093-100. PMID: 19240252.
    Citations:    
  28. Johnson ML, Pipes L, Veldhuis PP, Farhy LS, Nass R, Thorner MO, Evans WS. AutoDecon: a robust numerical method for the quantification of pulsatile events. Methods Enzymol. 2009; 454:367-404. PMID: 19216935.
    Citations:    
  29. Kim DS, Itoh E, Iida K, Thorner MO. Growth hormone increases mRNA levels of PPARdelta and Foxo1 in skeletal muscle of growth hormone deficient lit/lit mice. Endocr J. 2009; 56(1):141-7. PMID: 18997443.
    Citations:    
  30. Nass R, Pezzoli SS, Oliveri MC, Patrie JT, Harrell FE, Clasey JL, Heymsfield SB, Bach MA, Vance ML, Thorner MO. Effects of an oral ghrelin mimetic on body composition and clinical outcomes in healthy older adults: a randomized trial. Ann Intern Med. 2008 Nov 04; 149(9):601-11. PMID: 18981485.
    Citations: 61     Fields:    Translation:Humans
  31. Nass R, Johannsson G, Christiansen JS, Kopchick JJ, Thorner MO. The aging population--is there a role for endocrine interventions? Growth Horm IGF Res. 2009 Apr; 19(2):89-100. PMID: 18977675.
    Citations:    
  32. Berryman DE, Christiansen JS, Johannsson G, Thorner MO, Kopchick JJ. Role of the GH/IGF-1 axis in lifespan and healthspan: lessons from animal models. Growth Horm IGF Res. 2008 Dec; 18(6):455-71. PMID: 18710818.
    Citations:    
  33. Jimenez C, Burman P, Abs R, Clemmons DR, Drake WM, Hutson KR, Messig M, Thorner MO, Trainer PJ, Gagel RF. Follow-up of pituitary tumor volume in patients with acromegaly treated with pegvisomant in clinical trials. Eur J Endocrinol. 2008 Nov; 159(5):517-23. PMID: 18708436.
    Citations:    
  34. Darzy KH, Thorner MO, Shalet SM. Cranially irradiated adult cancer survivors may have normal spontaneous GH secretion in the presence of discordant peak GH responses to stimulation tests (compensated GH deficiency). Clin Endocrinol (Oxf). 2009 Feb; 70(2):287-93. PMID: 18673465.
    Citations:    
  35. Chan JL, Williams CJ, Raciti P, Blakeman J, Kelesidis T, Kelesidis I, Johnson ML, Thorner MO, Mantzoros CS. Leptin does not mediate short-term fasting-induced changes in growth hormone pulsatility but increases IGF-I in leptin deficiency states. J Clin Endocrinol Metab. 2008 Jul; 93(7):2819-27. PMID: 18445667.
    Citations: 17     Fields:    Translation:Humans
  36. Liu J, Prudom CE, Nass R, Pezzoli SS, Oliveri MC, Johnson ML, Veldhuis P, Gordon DA, Howard AD, Witcher DR, Geysen HM, Gaylinn BD, Thorner MO. Novel ghrelin assays provide evidence for independent regulation of ghrelin acylation and secretion in healthy young men. J Clin Endocrinol Metab. 2008 May; 93(5):1980-7. PMID: 18349056.
    Citations:    
  37. Nass R, Farhy LS, Liu J, Prudom CE, Johnson ML, Veldhuis P, Pezzoli SS, Oliveri MC, Gaylinn BD, Geysen HM, Thorner MO. Evidence for acyl-ghrelin modulation of growth hormone release in the fed state. J Clin Endocrinol Metab. 2008 May; 93(5):1988-94. PMID: 18334589.
    Citations:    
  38. Foster-Schubert KE, Overduin J, Prudom CE, Liu J, Callahan HS, Gaylinn BD, Thorner MO, Cummings DE. Acyl and total ghrelin are suppressed strongly by ingested proteins, weakly by lipids, and biphasically by carbohydrates. J Clin Endocrinol Metab. 2008 May; 93(5):1971-9. PMID: 18198223.
    Citations:    
  39. Li G, Del Rincon JP, Jahn LA, Wu Y, Gaylinn B, Thorner MO, Liu Z. Growth hormone exerts acute vascular effects independent of systemic or muscle insulin-like growth factor I. J Clin Endocrinol Metab. 2008 Apr; 93(4):1379-85. PMID: 18182451.
    Citations:    
  40. Patil CG, Prevedello DM, Lad SP, Vance ML, Thorner MO, Katznelson L, Laws ER. Late recurrences of Cushing's disease after initial successful transsphenoidal surgery. J Clin Endocrinol Metab. 2008 Feb; 93(2):358-62. PMID: 18056770.
    Citations: 47     Fields:    Translation:Humans
  41. del Rincon JP, Iida K, Gaylinn BD, McCurdy CE, Leitner JW, Barbour LA, Kopchick JJ, Friedman JE, Draznin B, Thorner MO. Growth hormone regulation of p85alpha expression and phosphoinositide 3-kinase activity in adipose tissue: mechanism for growth hormone-mediated insulin resistance. Diabetes. 2007 Jun; 56(6):1638-46. PMID: 17363744.
    Citations:    
  42. Nass R, Park J, Thorner MO. Growth hormone supplementation in the elderly. Endocrinol Metab Clin North Am. 2007 Mar; 36(1):233-45. PMID: 17336743.
    Citations:    
  43. Darzy KH, Pezzoli SS, Thorner MO, Shalet SM. Cranial irradiation and growth hormone neurosecretory dysfunction: a critical appraisal. J Clin Endocrinol Metab. 2007 May; 92(5):1666-72. PMID: 17284618.
    Citations:    
  44. Darzy KH, Murray RD, Gleeson HK, Pezzoli SS, Thorner MO, Shalet SM. The impact of short-term fasting on the dynamics of 24-hour growth hormone (GH) secretion in patients with severe radiation-induced GH deficiency. J Clin Endocrinol Metab. 2006 Mar; 91(3):987-94. PMID: 16384844.
    Citations:    
  45. Melmed S, Casanueva F, Cavagnini F, Chanson P, Frohman LA, Gaillard R, Ghigo E, Ho K, Jaquet P, Kleinberg D, Lamberts S, Laws E, Lombardi G, Sheppard MC, Thorner M, Vance ML, Wass JA, Giustina A. Consensus statement: medical management of acromegaly. Eur J Endocrinol. 2005 Dec; 153(6):737-40. PMID: 16322377.
    Citations: 66     Fields:    Translation:Humans
  46. Iida K, Rosen CJ, Ackert-Bicknell C, Thorner MO. Genetic differences in the IGF-I gene among inbred strains of mice with different serum IGF-I levels. J Endocrinol. 2005 Sep; 186(3):481-9. PMID: 16135668.
    Citations:    
  47. Munafo A, Nguyen TX, Papasouliotis O, Lécuelle H, Priestley A, Thorner MO. Polyethylene glycol-conjugated growth hormone-releasing hormone is long acting and stimulates GH in healthy young and elderly subjects. Eur J Endocrinol. 2005 Aug; 153(2):249-56. PMID: 16061831.
    Citations:    
  48. Darzy KH, Pezzoli SS, Thorner MO, Shalet SM. The dynamics of growth hormone (GH) secretion in adult cancer survivors with severe GH deficiency acquired after brain irradiation in childhood for nonpituitary brain tumors: evidence for preserved pulsatility and diurnal variation with increased secretory disorderliness. J Clin Endocrinol Metab. 2005 May; 90(5):2794-803. PMID: 15728206.
    Citations:    
  49. Itoh E, Iida K, Kim DS, Del Rincon JP, Coschigano KT, Kopchick JJ, Thorner MO. Lack of contribution of 11betaHSD1 and glucocorticoid action to reduced muscle mass associated with reduced growth hormone action. Growth Horm IGF Res. 2004 Dec; 14(6):462-6. PMID: 15519255.
    Citations:    
  50. Itoh E, Iida K, del Rincon JP, Kim DS, Thorner MO. Diurnal variation in growth hormone receptor messenger ribonucleic acid in liver and skeletal muscle of lit/+ and lit/lit mice. Endocr J. 2004 Dec; 51(6):529-35. PMID: 15644570.
    Citations:    
  51. Iida K, Itoh E, Kim DS, del Rincon JP, Coschigano KT, Kopchick JJ, Thorner MO. Muscle mechano growth factor is preferentially induced by growth hormone in growth hormone-deficient lit/lit mice. J Physiol. 2004 Oct 15; 560(Pt 2):341-9. PMID: 15308683.
    Citations:    
  52. Leung GK, Lopes MB, Thorner MO, Vance ML, Laws ER. Primary hypophysitis: a single-center experience in 16 cases. J Neurosurg. 2004 Aug; 101(2):262-71. PMID: 15309917.
    Citations: 23     Fields:    Translation:Humans
  53. Nass R, Liu J, Hellmann P, Coschigano KT, Gaylinn B, Berryman DE, Kopchick JJ, Thorner MO. Chronic changes in peripheral growth hormone levels do not affect ghrelin stomach mRNA expression and serum ghrelin levels in three transgenic mouse models. J Neuroendocrinol. 2004 Aug; 16(8):669-75. PMID: 15271059.
    Citations:    
  54. Iida K, del Rincon JP, Kim DS, Itoh E, Coschigano KT, Kopchick JJ, Thorner MO. Regulation of full-length and truncated growth hormone (GH) receptor by GH in tissues of lit/lit or bovine GH transgenic mice. Am J Physiol Endocrinol Metab. 2004 Sep; 287(3):E566-73. PMID: 15165994.
    Citations:    
  55. Hoffman AR, Kuntze JE, Baptista J, Baum HB, Baumann GP, Biller BM, Clark RV, Cook D, Inzucchi SE, Kleinberg D, Klibanski A, Phillips LS, Ridgway EC, Robbins RJ, Schlechte J, Sharma M, Thorner MO, Vance ML. Growth hormone (GH) replacement therapy in adult-onset gh deficiency: effects on body composition in men and women in a double-blind, randomized, placebo-controlled trial. J Clin Endocrinol Metab. 2004 May; 89(5):2048-56. PMID: 15126520.
    Citations: 31     Fields:    Translation:HumansCTClinical Trials
  56. Iida K, Del Rincon JP, Kim DS, Itoh E, Nass R, Coschigano KT, Kopchick JJ, Thorner MO. Tissue-specific regulation of growth hormone (GH) receptor and insulin-like growth factor-I gene expression in the pituitary and liver of GH-deficient (lit/lit) mice and transgenic mice that overexpress bovine GH (bGH) or a bGH antagonist. Endocrinology. 2004 Apr; 145(4):1564-70. PMID: 14726438.
    Citations:    
  57. Clemmons DR, Chihara K, Freda PU, Ho KK, Klibanski A, Melmed S, Shalet SM, Strasburger CJ, Trainer PJ, Thorner MO. Optimizing control of acromegaly: integrating a growth hormone receptor antagonist into the treatment algorithm. J Clin Endocrinol Metab. 2003 Oct; 88(10):4759-67. PMID: 14557452.
    Citations: 13     Fields:    Translation:Humans
  58. Thorner MO. Controversy: radiotherapy for acromegaly. Clin Endocrinol (Oxf). 2003 Feb; 58(2):136-7. PMID: 12580926.
    Citations:    
  59. Nass R, Pezzoli SS, Chapman IM, Patrie J, Hintz RL, Hartman ML, Thorner MO. IGF-I does not affect the net increase in GH release in response to arginine. Am J Physiol Endocrinol Metab. 2002 Oct; 283(4):E702-10. PMID: 12217887.
    Citations:    
  60. Nass R, Thorner MO. Impact of the GH-cortisol ratio on the age-dependent changes in body composition. Growth Horm IGF Res. 2002 Jun; 12(3):147-61. PMID: 12162996.
    Citations:    
  61. Maheshwari HG, Pezzoli SS, Rahim A, Shalet SM, Thorner MO, Baumann G. Pulsatile growth hormone secretion persists in genetic growth hormone-releasing hormone resistance. Am J Physiol Endocrinol Metab. 2002 Apr; 282(4):E943-51. PMID: 11882517.
    Citations:    
  62. Simpson H, Savine R, Sönksen P, Bengtsson BA, Carlsson L, Christiansen JS, Clemmons D, Cohen P, Hintz R, Ho K, Mullis P, Robinson I, Strasburger C, Tanaka T, Thorner M. Growth hormone replacement therapy for adults: into the new millennium. Growth Horm IGF Res. 2002 Feb; 12(1):1-33. PMID: 12127299.
    Citations:    
  63. van der Lely AJ, Hutson RK, Trainer PJ, Besser GM, Barkan AL, Katznelson L, Klibanski A, Herman-Bonert V, Melmed S, Vance ML, Freda PU, Stewart PM, Friend KE, Clemmons DR, Johannsson G, Stavrou S, Cook DM, Phillips LS, Strasburger CJ, Hackett S, Zib KA, Davis RJ, Scarlett JA, Thorner MO. Long-term treatment of acromegaly with pegvisomant, a growth hormone receptor antagonist. Lancet. 2001 Nov 24; 358(9295):1754-9. PMID: 11734231.
    Citations: 96     Fields:    Translation:HumansCTClinical Trials
  64. Clasey JL, Weltman A, Patrie J, Weltman JY, Pezzoli S, Bouchard C, Thorner MO, Hartman ML. Abdominal visceral fat and fasting insulin are important predictors of 24-hour GH release independent of age, gender, and other physiological factors. J Clin Endocrinol Metab. 2001 Aug; 86(8):3845-52. PMID: 11502822.
    Citations:    
  65. Horikawa R, Gaylinn BD, Lyons CE, Thorner MO. Molecular cloning of ovine and bovine growth hormone-releasing hormone receptors: the ovine receptor is C-terminally truncated. Endocrinology. 2001 Jun; 142(6):2660-8. PMID: 11356717.
    Citations:    
  66. Murray RD, Peacey SR, Rahim A, Toogood AA, Thorner MO, Shalet SM. The diagnosis of growth hormone deficiency (GHD) in successfully treated acromegalic patients. Clin Endocrinol (Oxf). 2001 Jan; 54(1):37-44. PMID: 11167924.
    Citations:    
  67. Peacey SR, Toogood AA, Veldhuis JD, Thorner MO, Shalet SM. The relationship between 24-hour growth hormone secretion and insulin-like growth factor I in patients with successfully treated acromegaly: impact of surgery or radiotherapy. J Clin Endocrinol Metab. 2001 Jan; 86(1):259-66. PMID: 11232010.
    Citations:    
  68. Nass R, Toogood AA, Hellmann P, Bissonette E, Gaylinn B, Clark R, Thorner MO. Intracerebroventricular administration of the rat growth hormone (GH) receptor antagonist G118R stimulates GH secretion: evidence for the existence of short loop negative feedback of GH. J Neuroendocrinol. 2000 Dec; 12(12):1194-9. PMID: 11106977.
    Citations:    
  69. Meij BP, Lopes MB, Vance ML, Thorner MO, Laws ER. Double pituitary lesions in three patients with Cushing's disease. Pituitary. 2000 Nov; 3(3):159-68. PMID: 11383480.
    Citations: 19     Fields:    Translation:Humans
  70. Nass R, Gilrain J, Anderson S, Gaylinn B, Dalkin A, Day R, Peruggia M, Thorner MO. High plasma growth hormone (GH) levels inhibit expression of GH secretagogue receptor messenger ribonucleic acid levels in the rat pituitary. Endocrinology. 2000 Jun; 141(6):2084-9. PMID: 10830294.
    Citations:    
  71. Trainer PJ, Drake WM, Katznelson L, Freda PU, Herman-Bonert V, van der Lely AJ, Dimaraki EV, Stewart PM, Friend KE, Vance ML, Besser GM, Scarlett JA, Thorner MO, Parkinson C, Klibanski A, Powell JS, Barkan AL, Sheppard MC, Malsonado M, Rose DR, Clemmons DR, Johannsson G, Bengtsson BA, Stavrou S, Kleinberg DL, Cook DM, Phillips LS, Bidlingmaier M, Strasburger CJ, Hackett S, Zib K, Bennett WF, Davis RJ. Treatment of acromegaly with the growth hormone-receptor antagonist pegvisomant. N Engl J Med. 2000 Apr 20; 342(16):1171-7. PMID: 10770982.
    Citations: 108     Fields:    Translation:HumansCTClinical Trials
  72. Thorner MO. The discovery of growth hormone-releasing hormone. J Clin Endocrinol Metab. 1999 Dec; 84(12):4671-6. PMID: 10599736.
    Citations:    
  73. Pincus SM, Hartman ML, Roelfsema F, Thorner MO, Veldhuis JD. Hormone pulsatility discrimination via coarse and short time sampling. Am J Physiol. 1999 11; 277(5):E948-57. PMID: 10567024.
    Citations:    
  74. Gaylinn BD, Dealmeida VI, Lyons CE, Wu KC, Mayo KE, Thorner MO. The mutant growth hormone-releasing hormone (GHRH) receptor of the little mouse does not bind GHRH. Endocrinology. 1999 Nov; 140(11):5066-74. PMID: 10537133.
    Citations:    
  75. Thorner MO, Strasburger CJ, Wu Z, Straume M, Bidlingmaier M, Pezzoli SS, Zib K, Scarlett JC, Bennett WF. Growth hormone (GH) receptor blockade with a PEG-modified GH (B2036-PEG) lowers serum insulin-like growth factor-I but does not acutely stimulate serum GH. J Clin Endocrinol Metab. 1999 Jun; 84(6):2098-103. PMID: 10372717.
    Citations:    
  76. Skinner MM, Nass R, Lopes B, Laws ER, Thorner MO. Growth hormone secretagogue receptor expression in human pituitary tumors. J Clin Endocrinol Metab. 1998 Dec; 83(12):4314-20. PMID: 9851770.
    Citations: 6     Fields:    Translation:Humans
  77. Chapman IM, Hartman ML, Pieper KS, Skiles EH, Pezzoli SS, Hintz RL, Thorner MO. Recovery of growth hormone release from suppression by exogenous insulin-like growth factor I (IGF-I): evidence for a suppressive action of free rather than bound IGF-I. J Clin Endocrinol Metab. 1998 Aug; 83(8):2836-42. PMID: 9709956.
    Citations:    
  78. Thorner MO. Citation for the 1998 Monsanto Clinical Investigator Award of the Endocrine Society to Dr. Cyril Y. Bowers. Endocr Rev. 1998 Aug; 19(4):511. PMID: 9841200.
    Citations:    
  79. Iranmanesh A, South S, Liem AY, Clemmons D, Thorner MO, Weltman A, Veldhuis JD. Unequal impact of age, percentage body fat, and serum testosterone concentrations on the somatotrophic, IGF-I, and IGF-binding protein responses to a three-day intravenous growth hormone-releasing hormone pulsatile infusion in men. Eur J Endocrinol. 1998 Jul; 139(1):59-71. PMID: 9703380.
    Citations:    
  80. Gill MS, Toogood AA, O'Neill PA, Thorner MO, Shalet SM, Clayton PE. Urinary growth hormone (GH), insulin-like growth factor I (IGF-I), and IGF-binding protein-3 measurements in the diagnosis of adult GH deficiency. J Clin Endocrinol Metab. 1998 Jul; 83(7):2562-5. PMID: 9661643.
    Citations:    
  81. Moreno-Reyes R, Kerkhofs M, L'Hermite-Balériaux M, Thorner MO, Van Cauter E, Copinschi G. Evidence against a role for the growth hormone-releasing peptide axis in human slow-wave sleep regulation. Am J Physiol. 1998 05; 274(5):E779-84. PMID: 9612233.
    Citations:    
  82. Toogood AA, Jones J, O'Neill PA, Thorner MO, Shalet SM. The diagnosis of severe growth hormone deficiency in elderly patients with hypothalamic-pituitary disease. Clin Endocrinol (Oxf). 1998 May; 48(5):569-76. PMID: 9666868.
    Citations:    
  83. Chapman IM, Pescovitz OH, Murphy G, Treep T, Cerchio KA, Krupa D, Gertz B, Polvino WJ, Skiles EH, Pezzoli SS, Thorner MO. Oral administration of growth hormone (GH) releasing peptide-mimetic MK-677 stimulates the GH/insulin-like growth factor-I axis in selected GH-deficient adults. J Clin Endocrinol Metab. 1997 Oct; 82(10):3455-63. PMID: 9329386.
    Citations:    
  84. Thapar K, Kovacs K, Stefaneanu L, Scheithauer B, Killinger DW, Lioyd RV, Smyth HS, Barr A, Thorner MO, Gaylinn B, Laws ER. Overexpression of the growth-hormone-releasing hormone gene in acromegaly-associated pituitary tumors. An event associated with neoplastic progression and aggressive behavior. Am J Pathol. 1997 Sep; 151(3):769-84. PMID: 9284826.
    Citations: 20     Fields:    Translation:Humans
  85. Chapman IM, Hartman ML, Pezzoli SS, Harrell FE, Hintz RL, Alberti KG, Thorner MO. Effect of aging on the sensitivity of growth hormone secretion to insulin-like growth factor-I negative feedback. J Clin Endocrinol Metab. 1997 Sep; 82(9):2996-3004. PMID: 9284733.
    Citations:    
  86. Gill MS, Toogood AA, O'Neill PA, Adams JE, Thorner MO, Shalet SM, Clayton PE. Relationship between growth hormone (GH) status, serum leptin and body composition in healthy and GH deficient elderly subjects. Clin Endocrinol (Oxf). 1997 Aug; 47(2):161-7. PMID: 9302388.
    Citations:    
  87. Toogood AA, Nass RM, Pezzoli SS, O'Neill PA, Thorner MO, Shalet SM. Preservation of growth hormone pulsatility despite pituitary pathology, surgery, and irradiation. J Clin Endocrinol Metab. 1997 Jul; 82(7):2215-21. PMID: 9215297.
    Citations:    
  88. Lopes MB, Gaylinn BD, Thorner MO, Stoler MH. Growth hormone-releasing hormone receptor mRNA in acromegalic pituitary tumors. Am J Pathol. 1997 Jun; 150(6):1885-91. PMID: 9176381.
    Citations:    
  89. Molitch ME, Thorner MO, Wilson C. Management of prolactinomas. J Clin Endocrinol Metab. 1997 Apr; 82(4):996-1000. PMID: 9100563.
    Citations:    
  90. Kirk SE, Gertz BJ, Schneider SH, Hartman ML, Pezzoli SS, Wittreich JM, Krupa DA, Seibold JR, Thorner MO. Effect of obesity and feeding on the growth hormone (GH) response to the GH secretagogue L-692,429 in young men. J Clin Endocrinol Metab. 1997 Apr; 82(4):1154-9. PMID: 9100588.
    Citations:    
  91. Thorner MO. Theodore R. Woodward Award. Age-related decline in growth hormone secretion: clinical significance and potential reversibility. Trans Am Clin Climatol Assoc. 1997; 108:99-105; discussion 105-8. PMID: 9108670.
    Citations:    
  92. Thorner MO, Chapman IM, Gaylinn BD, Pezzoli SS, Hartman ML. Growth hormone-releasing hormone and growth hormone-releasing peptide as therapeutic agents to enhance growth hormone secretion in disease and aging. Recent Prog Horm Res. 1997; 52:215-44; discussion 244-6. PMID: 9238854.
    Citations:    
  93. Chapman IM, Bach MA, Van Cauter E, Farmer M, Krupa D, Taylor AM, Schilling LM, Cole KY, Skiles EH, Pezzoli SS, Hartman ML, Veldhuis JD, Gormley GJ, Thorner MO. Stimulation of the growth hormone (GH)-insulin-like growth factor I axis by daily oral administration of a GH secretogogue (MK-677) in healthy elderly subjects. J Clin Endocrinol Metab. 1996 Dec; 81(12):4249-57. PMID: 8954023.
    Citations:    
  94. Chapman IM, Hartman ML, Pezzoli SS, Thorner MO. Enhancement of pulsatile growth hormone secretion by continuous infusion of a growth hormone-releasing peptide mimetic, L-692,429, in older adults--a clinical research center study. J Clin Endocrinol Metab. 1996 Aug; 81(8):2874-80. PMID: 8768844.
    Citations:    
  95. Copinschi G, Van Onderbergen A, L'Hermite-Balériaux M, Mendel CM, Caufriez A, Leproult R, Bolognese JA, De Smet M, Thorner MO, Van Cauter E. Effects of a 7-day treatment with a novel, orally active, growth hormone (GH) secretagogue, MK-677, on 24-hour GH profiles, insulin-like growth factor I, and adrenocortical function in normal young men. J Clin Endocrinol Metab. 1996 Aug; 81(8):2776-82. PMID: 8768828.
    Citations:    
  96. Laws ER, Thorner MO, Vance ML. Bromocriptine therapy for prolactin-secreting pituitary adenomas. Neurosurg Focus. 1996 Jul 15; 1(1):e4; discussion 1p following e6. PMID: 15095998.
    Citations: 2     Fields:    
  97. Hartman ML, Pezzoli SS, Hellmann PJ, Suratt PM, Thorner MO. Pulsatile growth hormone secretion in older persons is enhanced by fasting without relationship to sleep stages. J Clin Endocrinol Metab. 1996 Jul; 81(7):2694-701. PMID: 8675598.
    Citations:    
  98. Friend KE, Hartman ML, Pezzoli SS, Clasey JL, Thorner MO. Both oral and transdermal estrogen increase growth hormone release in postmenopausal women--a clinical research center study. J Clin Endocrinol Metab. 1996 Jun; 81(6):2250-6. PMID: 8964860.
    Citations:    
  99. Thorner M, Rochiccioli P, Colle M, Lanes R, Grunt J, Galazka A, Landy H, Eengrand P, Shah S. Once daily subcutaneous growth hormone-releasing hormone therapy accelerates growth in growth hormone-deficient children during the first year of therapy. Geref International Study Group. J Clin Endocrinol Metab. 1996 Mar; 81(3):1189-96. PMID: 8772599.
    Citations:    
  100. Bergendahl M, Vance ML, Iranmanesh A, Thorner MO, Veldhuis JD. Fasting as a metabolic stress paradigm selectively amplifies cortisol secretory burst mass and delays the time of maximal nyctohemeral cortisol concentrations in healthy men. J Clin Endocrinol Metab. 1996 Feb; 81(2):692-9. PMID: 8636290.
    Citations:    
  101. Melmed S, Ho K, Klibanski A, Reichlin S, Thorner M. Clinical review 75: Recent advances in pathogenesis, diagnosis, and management of acromegaly. J Clin Endocrinol Metab. 1995 Dec; 80(12):3395-402. PMID: 8530571.
    Citations: 37     Fields:    Translation:Humans
  102. Thorner MO, Bengtsson BA, Ho KY, Albertsson-Wikland K, Christiansen JS, Faglia G, Irie M, Isaksson O, Jörgensen JO, Ranke M, et al. The diagnosis of growth hormone deficiency (GHD) in adults. J Clin Endocrinol Metab. 1995 Oct; 80(10):3097-8. PMID: 7559905.
    Citations:    
  103. Thorner MO, Hartman ML, Vance ML, Pezzoli SS, Ampleford EJ. Neuroendocrine regulation of growth hormone secretion. Neurosci Biobehav Rev. 1995; 19(3):465-8. PMID: 7566747.
    Citations:    
  104. Silva CM, Lu H, Weber MJ, Thorner MO. Differential tyrosine phosphorylation of JAK1, JAK2, and STAT1 by growth hormone and interferon-gamma in IM-9 cells. J Biol Chem. 1994 Nov 04; 269(44):27532-9. PMID: 7525556.
    Citations:    
  105. Aloi JA, Gertz BJ, Hartman ML, Huhn WC, Pezzoli SS, Wittreich JM, Krupa DA, Thorner MO. Neuroendocrine responses to a novel growth hormone secretagogue, L-692,429, in healthy older subjects. J Clin Endocrinol Metab. 1994 Oct; 79(4):943-9. PMID: 7962302.
    Citations:    
  106. Clayton PE, Day RN, Silva CM, Hellmann P, Day KH, Thorner MO. Growth hormone induces tyrosine phosphorylation but does not alter insulin-like growth factor-I gene expression in human IM9 lymphocytes. J Mol Endocrinol. 1994 Oct; 13(2):127-36. PMID: 7848524.
    Citations:    
  107. Hartman ML, Pincus SM, Johnson ML, Matthews DH, Faunt LM, Vance ML, Thorner MO, Veldhuis JD. Enhanced basal and disorderly growth hormone secretion distinguish acromegalic from normal pulsatile growth hormone release. J Clin Invest. 1994 Sep; 94(3):1277-88. PMID: 8083369.
    Citations:    
  108. Gaylinn BD, Lyons CE, Zysk JR, Clarke IJ, Thorner MO. Photoaffinity cross-linking to the pituitary receptor for growth hormone-releasing factor. Endocrinology. 1994 Sep; 135(3):950-5. PMID: 8070391.
    Citations:    
  109. Chapman IM, Hartman ML, Straume M, Johnson ML, Veldhuis JD, Thorner MO. Enhanced sensitivity growth hormone (GH) chemiluminescence assay reveals lower postglucose nadir GH concentrations in men than women. J Clin Endocrinol Metab. 1994 Jun; 78(6):1312-9. PMID: 8200931.
    Citations:    
  110. Gaylinn BD, von Kap-Herr C, Golden WL, Thorner MO. Assignment of the human growth hormone-releasing hormone receptor gene (GHRHR) to 7p14 by in situ hybridization. Genomics. 1994 Jan 01; 19(1):193-5. PMID: 8188233.
    Citations:    
  111. Silva CM, Day RN, Weber MJ, Thorner MO. Human growth hormone (GH) receptor is characterized as the 134-kilodalton tyrosine-phosphorylated protein activated by GH treatment in IM-9 cells. Endocrinology. 1993 Nov; 133(5):2307-12. PMID: 7691587.
    Citations:    
  112. Hartman ML, Clayton PE, Johnson ML, Celniker A, Perlman AJ, Alberti KG, Thorner MO. A low dose euglycemic infusion of recombinant human insulin-like growth factor I rapidly suppresses fasting-enhanced pulsatile growth hormone secretion in humans. J Clin Invest. 1993 Jun; 91(6):2453-62. PMID: 8514857.
    Citations:    
  113. Huhn WC, Hartman ML, Pezzoli SS, Thorner MO. Twenty-four-hour growth hormone (GH)-releasing peptide (GHRP) infusion enhances pulsatile GH secretion and specifically attenuates the response to a subsequent GHRP bolus. J Clin Endocrinol Metab. 1993 May; 76(5):1202-8. PMID: 8496311.
    Citations:    
  114. Kerkhofs M, Van Cauter E, Van Onderbergen A, Caufriez A, Thorner MO, Copinschi G. Sleep-promoting effects of growth hormone-releasing hormone in normal men. Am J Physiol. 1993 Apr; 264(4 Pt 1):E594-8. PMID: 8476038.
    Citations:    
  115. Veldhuis JD, Iranmanesh A, Evans WS, Lizarralde G, Thorner MO, Vance ML. Amplitude suppression of the pulsatile mode of immunoradiometric luteinizing hormone release in fasting-induced hypoandrogenemia in normal men. J Clin Endocrinol Metab. 1993 Mar; 76(3):587-93. PMID: 8445014.
    Citations:    
  116. Gaylinn BD, Harrison JK, Zysk JR, Lyons CE, Lynch KR, Thorner MO. Molecular cloning and expression of a human anterior pituitary receptor for growth hormone-releasing hormone. Mol Endocrinol. 1993 Jan; 7(1):77-84. PMID: 7680413.
    Citations:    
  117. Hartman ML, Farello G, Pezzoli SS, Thorner MO. Oral administration of growth hormone (GH)-releasing peptide stimulates GH secretion in normal men. J Clin Endocrinol Metab. 1992 Jun; 74(6):1378-84. PMID: 1592884.
    Citations:    
  118. Van Cauter E, Kerkhofs M, Caufriez A, Van Onderbergen A, Thorner MO, Copinschi G. A quantitative estimation of growth hormone secretion in normal man: reproducibility and relation to sleep and time of day. J Clin Endocrinol Metab. 1992 Jun; 74(6):1441-50. PMID: 1592892.
    Citations:    
  119. Van Cauter E, Caufriez A, Kerkhofs M, Van Onderbergen A, Thorner MO, Copinschi G. Sleep, awakenings, and insulin-like growth factor-I modulate the growth hormone (GH) secretory response to GH-releasing hormone. J Clin Endocrinol Metab. 1992 Jun; 74(6):1451-9. PMID: 1592893.
    Citations:    
  120. Hartman ML, Veldhuis JD, Johnson ML, Lee MM, Alberti KG, Samojlik E, Thorner MO. Augmented growth hormone (GH) secretory burst frequency and amplitude mediate enhanced GH secretion during a two-day fast in normal men. J Clin Endocrinol Metab. 1992 Apr; 74(4):757-65. PMID: 1548337.
    Citations:    
  121. Goth MI, Lyons CE, Canny BJ, Thorner MO. Pituitary adenylate cyclase activating polypeptide, growth hormone (GH)-releasing peptide and GH-releasing hormone stimulate GH release through distinct pituitary receptors. Endocrinology. 1992 Feb; 130(2):939-44. PMID: 1346381.
    Citations:    
  122. Painson JC, Thorner MO, Krieg RJ, Tannenbaum GS. Short-term adult exposure to estradiol feminizes the male pattern of spontaneous and growth hormone-releasing factor-stimulated growth hormone secretion in the rat. Endocrinology. 1992 Jan; 130(1):511-9. PMID: 1345780.
    Citations:    
  123. Vance ML, Hartman ML, Thorner MO. Growth hormone and nutrition. Horm Res. 1992; 38 Suppl 1:85-8. PMID: 1295819.
    Citations:    
  124. Press M, Caprio S, Tamborlane WV, Bhushan R, Thorner M, Vale W, Rivier J, Sherwin RS. Pituitary response to growth hormone-releasing hormone in IDDM. Abnormal responses to insulin and hyperglycemia. Diabetes. 1992 Jan; 41(1):17-21. PMID: 1727733.
    Citations:    
  125. Barth RJ, Constant RB, Parker MW, Mueller GL, Kovacs K, Thorner MO. Preoperative diagnosis of acromegaly by growth hormone-releasing factor radioimmunoassay. Mil Med. 1991 Jul; 156(7):375-8. PMID: 1922854.
    Citations:    
  126. DeBell WK, Pezzoli SS, Thorner MO. Growth hormone (GH) secretion during continuous infusion of GH-releasing peptide: partial response attenuation. J Clin Endocrinol Metab. 1991 Jun; 72(6):1312-6. PMID: 2026752.
    Citations:    
  127. Leong DA, Thorner MO. A potential code of luteinizing hormone-releasing hormone-induced calcium ion responses in the regulation of luteinizing hormone secretion among individual gonadotropes. J Biol Chem. 1991 May 15; 266(14):9016-22. PMID: 2026609.
    Citations:    
  128. Holl RW, Hartman ML, Veldhuis JD, Taylor WM, Thorner MO. Thirty-second sampling of plasma growth hormone in man: correlation with sleep stages. J Clin Endocrinol Metab. 1991 Apr; 72(4):854-61. PMID: 2005213.
    Citations:    
  129. Hartman ML, Faria AC, Vance ML, Johnson ML, Thorner MO, Veldhuis JD. Temporal structure of in vivo growth hormone secretory events in humans. Am J Physiol. 1991 Jan; 260(1 Pt 1):E101-10. PMID: 1987784.
    Citations:    
  130. Thorner MO, Vance ML, Hartman ML, Holl RW, Evans WS, Veldhuis JD, Van Cauter E, Copinschi G, Bowers CY. Physiological role of somatostatin on growth hormone regulation in humans. Metabolism. 1990 Sep; 39(9 Suppl 2):40-2. PMID: 1976218.
    Citations:    
  131. Baumann G, Vance ML, Shaw MA, Thorner MO. Plasma transport of human growth hormone in vivo. J Clin Endocrinol Metab. 1990 Aug; 71(2):470-3. PMID: 2380341.
    Citations:    
  132. Hartman ML, Veldhuis JD, Vance ML, Faria AC, Furlanetto RW, Thorner MO. Somatotropin pulse frequency and basal concentrations are increased in acromegaly and are reduced by successful therapy. J Clin Endocrinol Metab. 1990 May; 70(5):1375-84. PMID: 2335577.
    Citations:    
  133. Bowers CY, Reynolds GA, Durham D, Barrera CM, Pezzoli SS, Thorner MO. Growth hormone (GH)-releasing peptide stimulates GH release in normal men and acts synergistically with GH-releasing hormone. J Clin Endocrinol Metab. 1990 Apr; 70(4):975-82. PMID: 2108187.
    Citations:    
  134. Thorner MO, Vance ML, Rogol AD, Blizzard RM, Veldhuis JD, Cauter EV, Copinschi G, Bowers CY. Growth hormone-releasing hormone and growth hormone-releasing peptide as potential therapeutic modalities. Acta Paediatr Scand Suppl. 1990; 367:29-32. PMID: 1977276.
    Citations:    
  135. Martha PM, Blizzard RM, Thorner MO, Rogol AD. Atenolol enhances nocturnal growth hormone (GH) release in GH-deficient children during long term GH-releasing hormone therapy. J Clin Endocrinol Metab. 1990 Jan; 70(1):56-61. PMID: 2104629.
    Citations:    
  136. Nemeroff CB, Krishnan KR, Belkin BM, Ritchie JC, Clark C, Vale WW, Rivier JE, Thorner MO. Growth hormone response to growth hormone releasing factor in Alzheimer's disease. Neuroendocrinology. 1989 Dec; 50(6):663-6. PMID: 2515465.
    Citations:    
  137. Vance ML, Thorner MO. Fasting alters pulsatile and rhythmic cortisol release in normal man. J Clin Endocrinol Metab. 1989 Jun; 68(6):1013-8. PMID: 2723024.
    Citations:    
  138. Faria AC, Veldhuis JD, Thorner MO, Vance ML. Half-time of endogenous growth hormone (GH) disappearance in normal man after stimulation of GH secretion by GH-releasing hormone and suppression with somatostatin. J Clin Endocrinol Metab. 1989 Mar; 68(3):535-41. PMID: 2563734.
    Citations:    
  139. Moller DE, Moses AC, Jones K, Thorner MO, Vance ML. Octreotide suppresses both growth hormone (GH) and GH-releasing hormone (GHRH) in acromegaly due to ectopic GHRH secretion. J Clin Endocrinol Metab. 1989 Feb; 68(2):499-504. PMID: 2493033.
    Citations:    
  140. Vance ML, Kaiser DL, Martha PM, Furlanetto R, Rivier J, Vale W, Thorner MO. Lack of in vivo somatotroph desensitization or depletion after 14 days of continuous growth hormone (GH)-releasing hormone administration in normal men and a GH-deficient boy. J Clin Endocrinol Metab. 1989 Jan; 68(1):22-8. PMID: 2491864.
    Citations:    
  141. Ho KY, Thorner MO, Krieg RJ, Lau SK, Sinha YN, Johnson ML, Leong DA, Evans WS. Effects of gonadal steroids on somatotroph function in the rat: analysis by the reverse hemolytic plaque assay. Endocrinology. 1988 Sep; 123(3):1405-11. PMID: 3136007.
    Citations:    
  142. Martha PM, Blizzard RM, McDonald JA, Thorner MO, Rogol AD. A persistent pattern of varying pituitary responsivity to exogenous growth hormone (GH)-releasing hormone in GH-deficient children: evidence supporting periodic somatostatin secretion. J Clin Endocrinol Metab. 1988 Sep; 67(3):449-54. PMID: 2900843.
    Citations:    
  143. Thorner MO, Vance ML. Growth hormone, 1988. J Clin Invest. 1988 Sep; 82(3):745-7. PMID: 3047168.
    Citations:    
  144. Thorner MO, Rogol AD, Blizzard RM, Klingensmith GJ, Najjar J, Misra R, Burr I, Chao G, Martha P, Mcdonald J, et al. Acceleration of growth rate in growth hormone-deficient children treated with human growth hormone-releasing hormone. Pediatr Res. 1988 Aug; 24(2):145-51. PMID: 3141891.
    Citations:    
  145. Ramsay JA, Kovacs K, Asa SL, Pike MJ, Thorner MO. Reversible sellar enlargement due to growth hormone-releasing hormone production by pancreatic endocrine tumors in a acromegalic patient with multiple endocrine neoplasia type I syndrome. Cancer. 1988 Jul 15; 62(2):445-50. PMID: 2898285.
    Citations:    
  146. Holl RW, Thorner MO, Mandell GL, Sullivan JA, Sinha YN, Leong DA. Spontaneous oscillations of intracellular calcium and growth hormone secretion. J Biol Chem. 1988 Jul 15; 263(20):9682-5. PMID: 2454918.
    Citations:    
  147. Ho KY, Thorner MO. Therapeutic applications of bromocriptine in endocrine and neurological diseases. Drugs. 1988 Jul; 36(1):67-82. PMID: 3063495.
    Citations:    
  148. Holl RW, Thorner MO, Leong DA. Intracellular calcium concentration and growth hormone secretion in individual somatotropes: effects of growth hormone-releasing factor and somatostatin. Endocrinology. 1988 Jun; 122(6):2927-32. PMID: 2453353.
    Citations:    
  149. Ho KY, Veldhuis JD, Johnson ML, Furlanetto R, Evans WS, Alberti KG, Thorner MO. Fasting enhances growth hormone secretion and amplifies the complex rhythms of growth hormone secretion in man. J Clin Invest. 1988 Apr; 81(4):968-75. PMID: 3127426.
    Citations:    
  150. Krishnan KR, Manepalli AN, Ritchie JC, Rayasam K, Melville ML, Thorner MO, Rivier JE, Vale WW, Nemeroff CB. Growth hormone response to growth hormone-releasing factor in depression. Peptides. 1988; 9 Suppl 1:113-6. PMID: 2856637.
    Citations:    
  151. Veldhuis JD, Faria A, Vance ML, Evans WS, Thorner MO, Johnson ML. Contemporary tools for the analysis of episodic growth hormone secretion and clearance in vivo. Acta Paediatr Scand Suppl. 1988; 347:63-82. PMID: 3075841.
    Citations:    
  152. Krishnan KR, Manepalli AN, Ritchie JC, Rayasam K, Melville ML, Daughtry G, Thorner MO, Rivier JE, Vale WW, Nemeroff CB, et al. Growth hormone-releasing factor stimulation test in depression. Am J Psychiatry. 1988 Jan; 145(1):90-2. PMID: 2827532.
    Citations:    
  153. Weiss J, Cronin MJ, Thorner MO. Periodic interactions of GH-releasing factor and somatostatin can augment GH release in vitro. Am J Physiol. 1987 Nov; 253(5 Pt 1):E508-14. PMID: 2891301.
    Citations:    
  154. Vance ML, Thorner MO. Prolactinomas. Endocrinol Metab Clin North Am. 1987 Sep; 16(3):731-53. PMID: 3319600.
    Citations:    
  155. Goldman JA, Molitch ME, Thorner MO, Vale W, Rivier J, Reichlin S. Growth hormone and prolactin responses to bolus and sustained infusions of GRH-1-40-OH in man. J Endocrinol Invest. 1987 Aug; 10(4):397-406. PMID: 3119697.
    Citations:    
  156. Koritnik DR, Cronin MJ, Orth DN, Evans WS, Thorner MO. Pituitary response to intravenous hypothalamic releasing peptides in cynomolgus monkeys treated with contraceptive steroids. J Clin Endocrinol Metab. 1987 Jul; 65(1):37-45. PMID: 3034957.
    Citations:    
  157. Vance ML, Kaiser DL, Frohman LA, Rivier J, Vale WW, Thorner MO. Role of dopamine in the regulation of growth hormone secretion: dopamine and bromocriptine augment growth hormone (GH)-releasing hormone-stimulated GH secretion in normal man. J Clin Endocrinol Metab. 1987 Jun; 64(6):1136-41. PMID: 3553220.
    Citations:    
  158. Evans WS, Faria AC, Christiansen E, Ho KY, Weiss J, Rogol AD, Johnson ML, Blizzard RM, Veldhuis JD, Thorner MO. Impact of intensive venous sampling on characterization of pulsatile GH release. Am J Physiol. 1987 Apr; 252(4 Pt 1):E549-56. PMID: 3565563.
    Citations:    
  159. Mauras N, Blizzard RM, Thorner MO, Rogol AD. Selective beta 1-adrenergic receptor-blockade with atenolol enhances growth hormone releasing hormone and mediated growth hormone release in man. Metabolism. 1987 Apr; 36(4):369-72. PMID: 2882405.
    Citations:    
  160. Ho KY, Evans WS, Blizzard RM, Veldhuis JD, Merriam GR, Samojlik E, Furlanetto R, Rogol AD, Kaiser DL, Thorner MO. Effects of sex and age on the 24-hour profile of growth hormone secretion in man: importance of endogenous estradiol concentrations. J Clin Endocrinol Metab. 1987 Jan; 64(1):51-8. PMID: 3782436.
    Citations:    
  161. Zysk JR, Cronin MJ, Anderson JM, Thorner MO. Cross-linking of a growth hormone releasing factor-binding protein in anterior pituitary cells. J Biol Chem. 1986 Dec 25; 261(36):16781-4. PMID: 3023363.
    Citations:    
  162. Vance ML, Evans WS, Kaiser DL, Burke RL, Rivier J, Vale W, Thorner MO. The effect of intravenous, subcutaneous, and intranasal GH-RH analog, [Nle27]GHRH(1-29)-NH2, on growth hormone secretion in normal men: dose-response relationships. Clin Pharmacol Ther. 1986 Dec; 40(6):627-33. PMID: 3096623.
    Citations:    
  163. Vance ML, Thorner MO. Growth-hormone-releasing hormone: a clinical update. Ann Intern Med. 1986 Sep; 105(3):447-9. PMID: 3090921.
    Citations:    
  164. Smith PJ, Brook CG, Rivier J, Vale W, Thorner MO. Nocturnal pulsatile growth hormone releasing hormone treatment in growth hormone deficiency. Clin Endocrinol (Oxf). 1986 Jul; 25(1):35-44. PMID: 3098459.
    Citations:    
  165. Chalew SA, Armour KM, Levin PA, Thorner MO, Kowarski AA. Growth hormone (GH) response to GH-releasing hormone in children with subnormal integrated concentrations of GH. J Clin Endocrinol Metab. 1986 Jun; 62(6):1110-5. PMID: 3084533.
    Citations:    
  166. Ho KY, Leong DA, Sinha YN, Johnson ML, Evans WS, Thorner MO. Sex-related differences in GH secretion in rat using reverse hemolytic plaque assay. Am J Physiol. 1986 Jun; 250(6 Pt 1):E650-4. PMID: 3087216.
    Citations:    
  167. Vance ML, Kaiser DL, Rivier J, Vale W, Thorner MO. Dual effects of growth hormone (GH)-releasing hormone infusion in normal men: somatotroph desensitization and increase in releasable GH. J Clin Endocrinol Metab. 1986 Mar; 62(3):591-4. PMID: 3080467.
    Citations:    
  168. Thorner MO, Vance ML, Evans WS, Blizzard RM, Rogol AD, Ho K, Leong DA, Borges JL, Cronin MJ, MacLeod RM, et al. Physiological and clinical studies of GRF and GH. Recent Prog Horm Res. 1986; 42:589-640. PMID: 3090660.
    Citations:    
  169. Thorner MO, Vance ML, Evans WS, Rogol AD, Rivier J, Vale W, Blizzard RM. Clinical studies with GHRH in man. Horm Res. 1986; 24(2-3):91-8. PMID: 3093355.
    Citations:    
  170. Thorner MO, Vance ML, Evans WS, Ho K, Rogol AD, Blizzard RM, Furlanetto R, Rivier J, Vale W. Growth hormone releasing factor and somatomedin C production: extrahypothalamic localization and possible functional significance. Acta Endocrinol Suppl (Copenh). 1986; 276:34-40. PMID: 3092530.
    Citations:    
  171. Perkins SN, Evans WS, Thorner MO, Gibbs DM, Cronin MJ. Beta-adrenergic binding and secretory responses of the anterior pituitary. Endocrinology. 1985 Nov; 117(5):1818-25. PMID: 2864235.
    Citations:    
  172. Evans WS, Vance ML, Kaiser DL, Sellers RP, Borges JL, Downs TR, Frohman LA, Rivier J, Vale W, Thorner MO. Effects of intravenous, subcutaneous, and intranasal administration of growth hormone (GH)-releasing hormone-40 on serum GH concentrations in normal men. J Clin Endocrinol Metab. 1985 Nov; 61(5):846-50. PMID: 3930551.
    Citations:    
  173. Veldhuis JD, Evans WS, Demers LM, Thorner MO, Wakat D, Rogol AD. Altered neuroendocrine regulation of gonadotropin secretion in women distance runners. J Clin Endocrinol Metab. 1985 Sep; 61(3):557-63. PMID: 3926810.
    Citations:    
  174. Cronin MJ, Anderson JM, Rogol AD, Koritnik DR, Thorner MO, Evans WS. Calcium channel agonist BAY k8644 enhances anterior pituitary secretion in rat and monkey. Am J Physiol. 1985 Sep; 249(3 Pt 1):E326-9. PMID: 2412450.
    Citations:    
  175. Evans WS, Krieg RJ, Limber ER, Kaiser DL, Thorner MO. Effects of in vivo gonadal hormone environment on in vitro hGRF-40-stimulated GH release. Am J Physiol. 1985 Sep; 249(3 Pt 1):E276-80. PMID: 3929617.
    Citations:    
  176. Williams T, Maxon H, Thorner MO, Frohman LA. Blunted growth hormone (GH) response to GH-releasing hormone in hypothyroidism resolves in the euthyroid state. J Clin Endocrinol Metab. 1985 Sep; 61(3):454-6. PMID: 3926807.
    Citations:    
  177. Vance ML, Ridgway EC, Thorner MO. Follicle-stimulating hormone- and alpha-subunit-secreting pituitary tumor treated with bromocriptine. J Clin Endocrinol Metab. 1985 Sep; 61(3):580-4. PMID: 2410444.
    Citations:    
  178. Rogol AD, Blizzard RM, Foley TP, Furlanetto R, Selden R, Mayo K, Thorner MO. Growth hormone releasing hormone and growth hormone: genetic studies in familial growth hormone deficiency. Pediatr Res. 1985 May; 19(5):489-92. PMID: 3923425.
    Citations:    
  179. Vance ML, Kaiser DL, Evans WS, Furlanetto R, Vale W, Rivier J, Thorner MO. Pulsatile growth hormone secretion in normal man during a continuous 24-hour infusion of human growth hormone releasing factor (1-40). Evidence for intermittent somatostatin secretion. J Clin Invest. 1985 May; 75(5):1584-90. PMID: 2860126.
    Citations:    
  180. Thorner MO, Reschke J, Chitwood J, Rogol AD, Furlanetto R, Rivier J, Vale W, Blizzard RM. Development of antibody to growth hormone-releasing factor. N Engl J Med. 1985 Apr 11; 312(15):994. PMID: 3919301.
    Citations:    
  181. Molitch ME, Elton RL, Blackwell RE, Caldwell B, Chang RJ, Jaffe R, Joplin G, Robbins RJ, Tyson J, Thorner MO. Bromocriptine as primary therapy for prolactin-secreting macroadenomas: results of a prospective multicenter study. J Clin Endocrinol Metab. 1985 Apr; 60(4):698-705. PMID: 3882737.
    Citations:    
  182. Sheldon WR, DeBold CR, Evans WS, DeCherney GS, Jackson RV, Island DP, Thorner MO, Orth DN. Rapid sequential intravenous administration of four hypothalamic releasing hormones as a combined anterior pituitary function test in normal subjects. J Clin Endocrinol Metab. 1985 Apr; 60(4):623-30. PMID: 2982903.
    Citations:    
  183. Asa SL, Kovacs K, Thorner MO, Leong DA, Rivier J, Vale W. Immunohistological localization of growth hormone-releasing hormone in human tumors. J Clin Endocrinol Metab. 1985 Mar; 60(3):423-7. PMID: 3919041.
    Citations:    
  184. Ho KY, Evans WS, Thorner MO. Disorders of prolactin and growth hormone secretion. Clin Endocrinol Metab. 1985 Feb; 14(1):1-32. PMID: 3926353.
    Citations:    
  185. Vance ML, Kaiser DL, Evans WS, Thorner MO, Furlanetto R, Rivier J, Vale W, Perisutti G, Frohman LA. Evidence for a limited growth hormone (GH)-releasing hormone (GHRH)-releasable quantity of GH: effects of 6-hour infusions of GHRH on GH secretion in normal man. J Clin Endocrinol Metab. 1985 Feb; 60(2):370-5. PMID: 3917460.
    Citations:    
  186. Thorner MO, Reschke J, Chitwood J, Rogol AD, Furlanetto R, Rivier J, Vale W, Blizzard RM. Acceleration of growth in two children treated with human growth hormone-releasing factor. N Engl J Med. 1985 Jan 03; 312(1):4-9. PMID: 3917299.
    Citations:    
  187. Veldhuis JD, Borges JL, Drake CR, Rogol AD, Kaiser DL, Thorner MO. Divergent influences of the structurally dissimilar calcium entry blockers, diltiazem and verapamil, on thyrotropin- and gonadotropin-releasing hormone-stimulated anterior pituitary hormone secretion in man. J Clin Endocrinol Metab. 1985 Jan; 60(1):144-9. PMID: 3880562.
    Citations:    
  188. Thorner MO, Evans WS, Vance M, Borges JL, Blizzard RM, Rogol AD, MacLeod RM, Cronin MJ, Frohman LA, Thominet JL, et al. Human pancreatic tumor GH-releasing factor. Acta Neurochir (Wien). 1985; 75(1-4):72-80. PMID: 2986423.
    Citations:    
  189. Williams T, Berelowitz M, Joffe SN, Thorner MO, Rivier J, Vale W, Frohman LA. Impaired growth hormone responses to growth hormone-releasing factor in obesity. A pituitary defect reversed with weight reduction. N Engl J Med. 1984 Nov 29; 311(22):1403-7. PMID: 6436706.
    Citations: 60     Fields:    Translation:Humans
  190. Evans WS, Borges JL, Vance ML, Kaiser DL, Rogol AD, Furlanetto R, Rivier J, Vale W, Thorner MO. Effects of human pancreatic growth hormone-releasing factor-40 on serum growth hormone, prolactin, luteinizing hormone, follicle-stimulating hormone, and somatomedin-C concentrations in normal women throughout the menstrual cycle. J Clin Endocrinol Metab. 1984 Nov; 59(5):1006-10. PMID: 6434583.
    Citations:    
  191. Thorner MO, Frohman LA, Leong DA, Thominet J, Downs T, Hellmann P, Chitwood J, Vaughan JM, Vale W. Extrahypothalamic growth-hormone-releasing factor (GRF) secretion is a rare cause of acromegaly: plasma GRF levels in 177 acromegalic patients. J Clin Endocrinol Metab. 1984 Nov; 59(5):846-9. PMID: 6434585.
    Citations:    
  192. Rogol AD, Blizzard RM, Johanson AJ, Furlanetto RW, Evans WS, Rivier J, Vale WW, Thorner MO. Growth hormone release in response to human pancreatic tumor growth hormone-releasing hormone-40 in children with short stature. J Clin Endocrinol Metab. 1984 Oct; 59(4):580-6. PMID: 6434572.
    Citations:    
  193. Schettini G, Cronin MJ, Hewlett EL, Thorner MO, MacLeod RM. Human pancreatic tumor growth hormone-releasing factor stimulates anterior pituitary adenylate cyclase activity, adenosine 3',5'-monophosphate accumulation, and growth hormone release in a calmodulin-dependent manner. Endocrinology. 1984 Oct; 115(4):1308-14. PMID: 6148231.
    Citations:    
  194. Veldhuis JD, Evans WS, Rogol AD, Drake CR, Thorner MO, Merriam GR, Johnson ML. Performance of LH pulse-detection algorithms at rapid rates of venous sampling in humans. Am J Physiol. 1984 Oct; 247(4 Pt 1):E554-63. PMID: 6496672.
    Citations:    
  195. Stolar MW, Baumann G, Vance ML, Thorner MO. Circulating growth hormone forms after stimulation of pituitary secretion with growth hormone-releasing factor in man. J Clin Endocrinol Metab. 1984 Aug; 59(2):235-9. PMID: 6429181.
    Citations:    
  196. Press M, Tamborlane WV, Thorner MO, Vale W, Rivier J, Gertner JM, Sherwin RS. Pituitary response to growth hormone-releasing factor in diabetes. Failure of glucose-mediated suppression. Diabetes. 1984 Aug; 33(8):804-6. PMID: 6430738.
    Citations:    
  197. Carey RM, Varma SK, Drake CR, Thorner MO, Kovacs K, Rivier J, Vale W. Ectopic secretion of corticotropin-releasing factor as a cause of Cushing's syndrome. A clinical, morphologic, and biochemical study. N Engl J Med. 1984 Jul 05; 311(1):13-20. PMID: 6328303.
    Citations:    
  198. Veldhuis JD, Evans WS, Rogol AD, Drake CR, Thorner MO, Merriam GR, Johnson ML. Intensified rates of venous sampling unmask the presence of spontaneous, high-frequency pulsations of luteinizing hormone in man. J Clin Endocrinol Metab. 1984 Jul; 59(1):96-102. PMID: 6725529.
    Citations:    
  199. Webb CB, Vance ML, Thorner MO, Perisutti G, Thominet J, Rivier J, Vale W, Frohman LA. Plasma growth hormone responses to constant infusions of human pancreatic growth hormone releasing factor. Intermittent secretion or response attenuation. J Clin Invest. 1984 Jul; 74(1):96-103. PMID: 6429198.
    Citations:    
  200. Borges JL, Blizzard RM, Evans WS, Furlanetto R, Rogol AD, Kaiser DL, Rivier J, Vale W, Thorner MO. Stimulation of growth hormone (GH) and somatomedin C in idiopathic GH-deficient subjects by intermittent pulsatile administration of synthetic human pancreatic tumor GH-releasing factor. J Clin Endocrinol Metab. 1984 Jul; 59(1):1-6. PMID: 6427267.
    Citations:    
  201. Frohman LA, Thominet JL, Webb CB, Vance ML, Uderman H, Rivier J, Vale W, Thorner MO. Metabolic clearance and plasma disappearance rates of human pancreatic tumor growth hormone releasing factor in man. J Clin Invest. 1984 May; 73(5):1304-11. PMID: 6425363.
    Citations:    
  202. Borges JL, Ridgway EC, Kovacs K, Rogol AD, Thorner MO. Follicle-stimulating hormone-secreting pituitary tumor with concomitant elevation of serum alpha-subunit levels. J Clin Endocrinol Metab. 1984 May; 58(5):937-41. PMID: 6200493.
    Citations:    
  203. Cronin MJ, Hewlett EL, Evans WS, Thorner MO, Rogol AD. Human pancreatic tumor growth hormone (GH) - releasing factor and cyclic adenosine 3',5'- monophosphate evoke GH release from anterior pituitary cells: the effects of pertussis toxin, cholera toxin, forskolin, and cycloheximide. Endocrinology. 1984 Mar; 114(3):904-13. PMID: 6141934.
    Citations:    
  204. Kovacs K, Horvath E, Thorner MO, Rogol AD. Mammosomatotroph hyperplasia associated with acromegaly and hyperprolactinemia in a patient with the McCune-Albright syndrome. A histologic, immunocytologic and ultrastructural study of the surgically-removed adenohypophysis. Virchows Arch A Pathol Anat Histopathol. 1984; 403(1):77-86. PMID: 6426154.
    Citations:    
  205. Vance ML, Evans WS, Thorner MO. Drugs five years later. Bromocriptine. Ann Intern Med. 1984 Jan; 100(1):78-91. PMID: 6229205.
    Citations:    
  206. Evans WS, Borges JL, Kaiser DL, Vance ML, Sellers RP, MacLeod RM, Vale W, Rivier J, Thorner MO. Intranasal administration of human pancreatic tumor GH-releasing factor-40 stimulates GH release in normal men. J Clin Endocrinol Metab. 1983 Nov; 57(5):1081-3. PMID: 6413525.
    Citations:    
  207. Borges JL, Uskavitch DR, Kaiser DL, Cronin MJ, Evans WS, Thorner MO. Human pancreatic growth hormone-releasing factor-40 (hpGRF-40) allows stimulation of GH release by TRH. Endocrinology. 1983 Oct; 113(4):1519-21. PMID: 6413195.
    Citations:    
  208. Borges JL, Scott D, Kaiser DL, Evans WS, Thorner MO. Ca+2 dependence of gonadotropin-releasing hormone-stimulated luteinizing hormone secretion: in vitro studies using continuously perifused dispersed rat anterior pituitary cells. Endocrinology. 1983 Aug; 113(2):557-62. PMID: 6347661.
    Citations:    
  209. Borges JL, Blizzard RM, Gelato MC, Furlanetto R, Rogol AD, Evans WS, Vance ML, Kaiser DL, MacLeod RM, Merriam GR, Loriaux DL, Spiess J, Rivier J, Vale W, Thorner MO. Effects of human pancreatic tumour growth hormone releasing factor on growth hormone and somatomedin C levels in patients with idiopathic growth hormone deficiency. Lancet. 1983 Jul 16; 2(8342):119-24. PMID: 6134978.
    Citations:    
  210. Cronin MJ, Rogol AD, MacLeod RM, Keefer DA, Login IS, Borges JL, Thorner MO. Biological activity of a growth hormone-releasing factor secreted by a human tumor. Am J Physiol. 1983 Apr; 244(4):E346-53. PMID: 6404176.
    Citations:    
  211. Evans WS, Boykin BJ, Kaiser DL, Borges JL, Thorner MO. Biphasic luteinizing hormone secretion in response to gonadotropin-releasing hormone during continuous perifusion of dispersed rat anterior pituitary cells: changes in total release and the phasic components during the estrous cycle. Endocrinology. 1983 Feb; 112(2):535-42. PMID: 6336694.
    Citations:    
  212. Thorner MO, Rivier J, Spiess J, Borges JL, Vance ML, Bloom SR, Rogol AD, Cronin MJ, Kaiser DL, Evans WS, Webster JD, MacLeod RM, Vale W. Human pancreatic growth-hormone-releasing factor selectively stimulates growth-hormone secretion in man. Lancet. 1983 Jan 01; 1(8314-5):24-8. PMID: 6129370.
    Citations:    
  213. Tindall GT, Kovacs K, Horvath E, Thorner MO. Human prolactin-producing adenomas and bromocriptine: a histological, immunocytochemical, ultrastructural, and morphometric study. J Clin Endocrinol Metab. 1982 Dec; 55(6):1178-83. PMID: 6752167.
    Citations:    
  214. Login IS, Judd AM, Thorner MO, MacLeod RM. Reserpine inhibits rat anterior pituitary hormone secretion in vitro: effects on GH, TSH, and LH. . 1982 Dec; 171(3):247-50. PMID: 6294674.
    Citations:    
  215. Esch FS, Böhlen P, Ling NC, Brazeau PE, Wehrenberg WB, Thorner MO, Cronin MJ, Guillemin R. Characterization of a 40 residue peptide from a human pancreatic tumor with growth hormone releasing activity. Biochem Biophys Res Commun. 1982 Nov 16; 109(1):152-8. PMID: 7159418.
    Citations:    
  216. Thorner MO, Perryman RL, Cronin MJ, Rogol AD, Draznin M, Johanson A, Vale W, Horvath E, Kovacs K. Somatotroph hyperplasia. Successful treatment of acromegaly by removal of a pancreatic islet tumor secreting a growth hormone-releasing factor. J Clin Invest. 1982 Nov; 70(5):965-77. PMID: 6290540.
    Citations:    
  217. Cronin MJ, Rogol AD, Dabney LG, Thorner MO. Selective growth hormone and cyclic AMP stimulating activity is present in human pancreatic islet cell tumor. J Clin Endocrinol Metab. 1982 Aug; 55(2):381-3. PMID: 6123522.
    Citations:    
  218. Borges JL, Kaiser DL, Evans WS, Thorner MO. A model system for the study of luteinizing hormone (LH) secretion: lack of effect of fetal calf serum on gonadotropin-releasing hormone stimulated LH release. . 1982 May; 170(1):82-88. PMID: 7043472.
    Citations:    
  219. Thorner MO, Martin WH, Ragan GE, MacLeod RM, Feldman PS, Bruni C, Williamson BR, Orth DN. A case of ectopic ACTH syndrome: diagnostic difficulties caused by intermittent hormone secretion. Acta Endocrinol (Copenh). 1982 Mar; 99(3):364-70. PMID: 6280427.
    Citations:    
  220. Thorner MO, Perryman RL, Cronin MJ, Draznin MB, Johanson AJ, Rogol AD, Jane JA, Rudolf LE, Horvath E, Kovacs K, Vale W. Somatotroph hyperplasia: successful treatment of acromegaly by removal of a pancreatic islet tumor secreting a growth hormone-releasing factor. Trans Assoc Am Physicians. 1982; 95:177-87. PMID: 6304974.
    Citations:    
  221. Perryman RL, Rogol AD, Kaiser DL, MacLeod RM, Thorner MO. Pergolide mesylate: its effects on circulating anterior pituitary hormones in man. J Clin Endocrinol Metab. 1981 Oct; 53(4):772-8. PMID: 6793609.
    Citations:    
  222. Thorner MO, Perryman RL, Rogol AD, Conway BP, Macleod RM, Login IS, Morris JL. Rapid changes of prolactinoma volume after withdrawal and reinstitution of bromocriptine. J Clin Endocrinol Metab. 1981 Sep; 53(3):480-3. PMID: 7263835.
    Citations:    
  223. Martin WH, Rogol AD, Kaiser DL, Thorner MO. Dopaminergic mechanisms and luteinizing hormone (LH) secretion. II. Differential effects of dopamine and bromocriptine on LH release in normal women. J Clin Endocrinol Metab. 1981 Apr; 52(4):650-6. PMID: 7204538.
    Citations:    
  224. Thorner MO, Martin WH, Rogol AD, Morris JL, Perryman RL, Conway BP, Howards SS, Wolfman MG, MacLeod RM. Rapid regression of pituitary prolactinomas during bromocriptine treatment. J Clin Endocrinol Metab. 1980 Sep; 51(3):438-45. PMID: 6773972.
    Citations:    
  225. Thorner MO, Schran HF, Evans WS, Rogol AD, Morris JL, MacLeod RM. A broad spectrum of prolactin suppression by bromocriptine in hyperprolactinemic women: a study of serum prolactin and bromocriptine levels after acute and chronic admknistration of bromocriptine. J Clin Endocrinol Metab. 1980 Jun; 50(6):1026-33. PMID: 7189523.
    Citations:    
  226. Besser GM, Wass JA, Thorner MO. Bromocriptine in the medical management of acromegaly. Adv Biochem Psychopharmacol. 1980; 23:191-8. PMID: 6249090.
    Citations:    
  227. Evans WS, Rogol AD, MacLeod RM, Thorner MO. Dopaminergic mechanisms and luteinizing hormone secretion. I. Acute administration of the dopamine agonist bromocriptine does not inhibit luteinizing hormone release in hyperprolactinemic women. J Clin Endocrinol Metab. 1980 Jan; 50(1):103-7. PMID: 7188612.
    Citations:    
  228. Wass JA, Moult PJ, Thorner MO, Dacie JE, Charlesworth M, Jones AE, Besser GM. Reduction of pituitary-tumour size in patients with prolactinomas and acromegaly treated with bromocriptine with or without radiotherapy. Lancet. 1979 Jul 14; 2(8133):66-9. PMID: 87966.
    Citations:    
  229. Gomez-Pan A, Scanlon MF, Thorner MO, Rees LH, Schally AV, Hall R, Besser GM. Effect of somatostatin on abnormal growth hormone and prolactin secretion in patients with the carcinoid syndrome. Clin Endocrinol (Oxf). 1979 Jun; 10(6):575-81. PMID: 476984.
    Citations:    
  230. Thorner MO, Ryan SM, Wass JA, Jones A, Bouloux P, Williams S, Besser GM. Effect of the dopamine agonist, lergotrile mesylate, on circulating anterior pituitary hormones in man. J Clin Endocrinol Metab. 1978 Aug; 47(2):372-8. PMID: 45463.
    Citations:    
  231. Besser GM, Wass JA, Thorner MO. Acromegaly--results of long term treatment with bromocriptine. Acta Endocrinol Suppl (Copenh). 1978; 216:187-98. PMID: 347861.
    Citations:    
  232. Wass JA, Thorner MO, Morris DV, Rees LH, Mason AS, Jones AE, Besser GM. Long-term treatment of acromegaly with bromocriptine. Br Med J. 1977 Apr 02; 1(6065):875-8. PMID: 576843.
    Citations:    
  233. Thorner MO, Besser GM. Successful treatment of acromegaly with bromocriptine. Postgrad Med J. 1976; 52suppl 1:71-4. PMID: 959128.
    Citations:    
  234. Thorner MO, Chait A, Aitken M, Benker G, Bloom SR, Mortimer CH, Sanders P, Mason AS, Besser GM. Bromocriptine treatment of acromegaly. Br Med J. 1975 Feb 08; 1(5953):299-303. PMID: 1111790.
    Citations:    
  235. Besser GM, Mortimer CH, McNeilly AS, Thorner MO, Batistoni GA, Bloom SR, Kastrup KW, Hanssen KF, Hall R, Coy DH, Kastin AJ, Schally AV. Long-term infusion of growth hormone release inhibiting hormone in acromegaly: effects on pituitary and pancreatic hormones. Br Med J. 1974 Dec 14; 4(5945):622-7. PMID: 4374289.
    Citations:    
  236. Bloom SR, Mortimer CH, Thorner MO, Besser GM, Hall R, Gomez-Pan A, Roy VM, Russell RC, Coy DH, Kastin AJ, Schally AV. Inhibition of gastrin and gastric-acid secretion by growth-hormone release-inhibiting hormone. Lancet. 1974 Nov 09; 2(7889):1106-9. PMID: 4139406.
    Citations:    
  237. Besser GM, Mortimer CH, Carr D, Schally AV, Coy DH, Evered D, Kastin AJ, Tunbridge WM, Thorner MO, Hall R. Growth hormone release inhibiting hormone in acromegaly. Br Med J. 1974 Mar 02; 1(5904):352-5. PMID: 4594581.
    Citations:    
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.