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Jeffrey S Smith, Ph.D., M.D.

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Duke UniversityMD/PhDMedicine, Biochemistry
University of WashingtonBSNeurobiology, Chemistry
Alpha Omega Alpha

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Jfri A, Smith JS, Larocca C. Diagnosis of mycosis fungoides or Sézary syndrome after dupilumab use: A systematic review. J Am Acad Dermatol. 2022 Dec 05. PMID: 36481378.
    Citations:    Fields:    
  2. Schunkert EM, Smith JS, Elman SA, Merola JF. Extension-elicited blanching of the dorsal phalanges in systemic sclerosis: A case series. JAAD Case Rep. 2022 Dec; 30:87-90. PMID: 36411842; PMCID: PMC9674863.
  3. Elmariah SB, Smith JS, Merola JF. JAK in the [Black] Box: A Dermatology Perspective on Systemic JAK Inhibitor Safety. Am J Clin Dermatol. 2022 Jul; 23(4):427-431. PMID: 35679017.
    Citations:    Fields:    
  4. DeWane ME, Smith JS, DeSimone MS, Mostaghimi A. A case of refractory verrucous varicella zoster virus in a patient with persistent pancytopenia after CAR-T therapy. Br J Dermatol. 2022 09; 187(3):e77. PMID: 35575472.
    Citations:    Fields:    
  5. Zheng K, Smith JS, Eiger DS, Warman A, Choi I, Honeycutt CC, Boldizsar N, Gundry JN, Pack TF, Inoue A, Caron MG, Rajagopal S. Biased agonists of the chemokine receptor CXCR3 differentially signal through Gai:ß-arrestin complexes. Sci Signal. 2022 03 22; 15(726):eabg5203. PMID: 35316095.
    Citations:    Fields:    Translation:Cells
  6. Smith JS, Aldeeri AA, Elman SA, Krier JB, Merola JF. A novel variant in the GNAS complex locus causes Albright hereditary osteodystrophy with pseudopseudohypoparathyroidism. JAAD Case Rep. 2022 Mar; 21:103-105. PMID: 35198712; PMCID: PMC8850575.
  7. Suwanpradid J, Lee MJ, Hoang P, Kwock J, Floyd LP, Smith JS, Yin Z, Atwater AR, Rajagopal S, Kedl RM, Corcoran DL, Zhang JY, MacLeod AS. IL-27 Derived From Macrophages Facilitates IL-15 Production and T Cell Maintenance Following Allergic Hypersensitivity Responses. Front Immunol. 2021; 12:713304. PMID: 34659203.
    Citations: 4     Fields:    Translation:HumansAnimalsCells
  8. Rrapi R, Chand S, Gaffney R, Lo JA, Smith JS, Xia FD, Chen ST, Duncan LM, Foreman RK, Hartman RI, Hoang MP, Piris A, Walls AC, Kroshinsky D. Cutaneous mucormycosis arising in the skin folds of immunocompromised patients: A case series. JAAD Case Rep. 2021 Nov; 17:92-95. PMID: 34746347; PMCID: PMC8551783.
    Citations: 1     
  9. Smith JS, Pack TF. Noncanonical interactions of G proteins and ß-arrestins: from competitors to companions. FEBS J. 2021 04; 288(8):2550-2561. PMID: 33539669.
    Citations:    Fields:    Translation:HumansCells
  10. Smith JS, Said JT, Elman SA, Smith CEP, Merola JF. Seroconversion of severe acute respiratory syndrome coronavirus 2-infected patients on immunosuppression: A retrospective analysis. J Am Acad Dermatol. 2021 05; 84(5):1409-1412. PMID: 33549649.
    Citations: 2     Fields:    Translation:Humans
  11. Smith JS, Pack TF, Inoue A, Lee C, Zheng K, Choi I, Eiger DS, Warman A, Xiong X, Ma Z, Viswanathan G, Levitan IM, Rochelle LK, Staus DP, Snyder JC, Kahsai AW, Caron MG, Rajagopal S. Noncanonical scaffolding of Gai and ß-arrestin by G protein-coupled receptors. Science. 2021 03 12; 371(6534). PMID: 33479120; PMCID: PMC8005335.
    Citations: 19     Fields:    Translation:HumansCells
  12. Smith JS, Hanseler H, Welle J, Rattray R, Campbell M, Brotherton T, Moudgil T, Pack TF, Wegmann K, Jensen S, Jin J, Bifulco CB, Prahl SA, Fox BA, Stucky NL. Effect of various decontamination procedures on disposable N95 mask integrity and SARS-CoV-2 infectivity. J Clin Transl Sci. 2020 Jun 11; 5(1):e10. PMID: 34192045; PMCID: PMC7605403.
    Citations: 23     
  13. Tsai CF, Smith JS, Krajewski K, Zhao R, Moghieb AM, Nicora CD, Xiong X, Moore RJ, Liu T, Smith RD, Jacobs JM, Rajagopal S, Shi T. Tandem Mass Tag Labeling Facilitates Reversed-Phase Liquid Chromatography-Mass Spectrometry Analysis of Hydrophilic Phosphopeptides. Anal Chem. 2019 09 17; 91(18):11606-11613. PMID: 31418558; PMCID: PMC7197904.
    Citations: 4     Fields:    Translation:HumansCells
  14. Antonia AL, Gibbs KD, Trahair ED, Pittman KJ, Martin AT, Schott BH, Smith JS, Rajagopal S, Thompson JW, Reinhardt RL, Ko DC. Pathogen Evasion of Chemokine Response Through Suppression of CXCL10. Front Cell Infect Microbiol. 2019; 9:280. PMID: 31440475; PMCID: PMC6693555.
    Citations: 10     Fields:    Translation:HumansAnimalsCells
  15. Smith JS, Nicholson LT, Suwanpradid J, Glenn RA, Knape NM, Alagesan P, Gundry JN, Wehrman TS, Atwater AR, Gunn MD, MacLeod AS, Rajagopal S. Biased agonists of the chemokine receptor CXCR3 differentially control chemotaxis and inflammation. Sci Signal. 2018 11 06; 11(555). PMID: 30401786; PMCID: PMC6329291.
    Citations: 15     Fields:    Translation:HumansAnimalsCells
  16. Luttrell LM, Wang J, Plouffe B, Smith JS, Yamani L, Kaur S, Jean-Charles PY, Gauthier C, Lee MH, Pani B, Kim J, Ahn S, Rajagopal S, Reiter E, Bouvier M, Shenoy SK, Laporte SA, Rockman HA, Lefkowitz RJ. Manifold roles of ß-arrestins in GPCR signaling elucidated with siRNA and CRISPR/Cas9. Sci Signal. 2018 09 25; 11(549). PMID: 30254056; PMCID: PMC6369040.
    Citations: 75     Fields:    Translation:HumansCells
  17. Smith JS, Rajagopal S, Atwater AR. Chemokine Signaling in Allergic Contact Dermatitis: Toward Targeted Therapies. Dermatitis. 2018 Jul/Aug; 29(4):179-186. PMID: 29939854; PMCID: PMC6689816.
    Citations: 5     Fields:    Translation:HumansCells
  18. Smith JS, Suwanpradid J, MacLeod AS, Atwater AR. T Cells Expressing the Chemokine Receptor CXCR3 Localize to Positive Patch Test Reaction Sites. Dermatitis. 2018 Jul/Aug; 29(4):228-229. PMID: 29698357.
    Citations: 1     Fields:    Translation:HumansCells
  19. Smith JS, Lefkowitz RJ, Rajagopal S. Biased signalling: from simple switches to allosteric microprocessors. Nat Rev Drug Discov. 2018 04; 17(4):243-260. PMID: 29302067; PMCID: PMC5936084.
    Citations: 184     Fields:    Translation:HumansAnimalsCells
  20. Smith JS, Alagesan P, Desai NK, Pack TF, Wu JH, Inoue A, Freedman NJ, Rajagopal S. C-X-C Motif Chemokine Receptor 3 Splice Variants Differentially Activate Beta-Arrestins to Regulate Downstream Signaling Pathways. Mol Pharmacol. 2017 08; 92(2):136-150. PMID: 28559424; PMCID: PMC5508197.
    Citations: 25     Fields:    Translation:HumansCells
  21. Smith JS, Rajagopal S. The ß-Arrestins: Multifunctional Regulators of G Protein-coupled Receptors. J Biol Chem. 2016 Apr 22; 291(17):8969-77. PMID: 26984408.
    Citations: 104     Fields:    Translation:HumansAnimalsCells
  22. Smith JS, Angel TE, Chavkin C, Orton DJ, Moore RJ, Smith RD. Characterization of individual mouse cerebrospinal fluid proteomes. Proteomics. 2014 May; 14(9):1102-6. PMID: 24677814.
    Citations: 15     Fields:    Translation:Animals
  23. Schindler AG, Messinger DI, Smith JS, Shankar H, Gustin RM, Schattauer SS, Lemos JC, Chavkin NW, Hagan CE, Neumaier JF, Chavkin C. Stress produces aversion and potentiates cocaine reward by releasing endogenous dynorphins in the ventral striatum to locally stimulate serotonin reuptake. J Neurosci. 2012 Dec 05; 32(49):17582-96. PMID: 23223282.
    Citations: 52     Fields:    Translation:AnimalsCells
  24. Lemos JC, Wanat MJ, Smith JS, Reyes BA, Hollon NG, Van Bockstaele EJ, Chavkin C, Phillips PE. Severe stress switches CRF action in the nucleus accumbens from appetitive to aversive. Nature. 2012 Oct 18; 490(7420):402-6. PMID: 22992525.
    Citations: 121     Fields:    Translation:AnimalsCells
  25. Smith JS, Schindler AG, Martinelli E, Gustin RM, Bruchas MR, Chavkin C. Stress-induced activation of the dynorphin/?-opioid receptor system in the amygdala potentiates nicotine conditioned place preference. J Neurosci. 2012 Jan 25; 32(4):1488-95. PMID: 22279233.
    Citations: 50     Fields:    Translation:Animals
  26. Laskin A, Smith JS, Laskin J. Molecular characterization of nitrogen-containing organic compounds in biomass burning aerosols using high-resolution mass spectrometry. Environ Sci Technol. 2009 May 15; 43(10):3764-71. PMID: 19544885.
    Citations: 5     Fields:    
  27. Smith JS, Laskin A, Laskin J. Molecular characterization of biomass burning aerosols using high-resolution mass spectrometry. Anal Chem. 2009 Feb 15; 81(4):1512-21. PMID: 19115879.
    Citations: 4     Fields:    
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.