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Xuesong He, Ph.D., D.D.S.

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Biography
Beijing University, Beijing, ChinaDDS1997Dentistry
Indiana University, Bloomington, IN, USAPhD2006Microbiology
UCLA, Los Angeles, CAPostdoc2010Oral Microbiology

Overview
Trained as a dentist, I am fascinated with the host-associated microbial world and amazed by their significant roles in the host health and disease. I have been in the oral microbiology research field for over 15 years. I have extensive expertise in bacterial inter-species interactions, biofilm, bacterial genetics, microbial ecology, microbiome and microbial host interaction. Particularly, I am interested in achieving comprehensive understanding of the fundamental principles governing microbial host homeostasis as well as the impact of microbiome on host health and diseases. The following are some of the key research interests in the lab:
1)Achieving better understanding of host associated microbial ‘dark matter".
2)Studying the cross-kingdom trafficking of host generated molecules, such as sRNA in mediating the microbial host interaction.
3)Combating oral disease, such as dental caries and periodontitis, via targeted microbial modulation.
4)Understanding the interactions bridging the microbiome (gut and/or oral) and other systemic conditions.

Research
The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
  1. R01DE030943 (HE, XUESONG) Apr 1, 2022 - Mar 31, 2027
    NIH/NICDCR
    Host tRNA-derived small RNAs (tsRNAs) mediate interactions between host and oral microbes
    Role: Principle Investigator
  2. R01DE029479 (SUN, JIRUN) Sep 1, 2021 - Aug 31, 2026
    NIH
    Preventing dental caries through targeted treatment of acid-producing bacteria
    Role: Co-Principal Investigator
  3. R13DE031170 (HE, XUESONG) Jul 1, 2021 - Jun 30, 2022
    NIH
    Oral Microbiome: Beyond Bacteria
    Role: Principal Investigator
  4. R21DE029925 (SUN, JIRUN) Sep 1, 2020 - Aug 31, 2022
    NIH
    pH-sensitive materials responding to metabolic activities of cariogenic plaque
    Role: Co-Principal Investigator
  5. R01DE023810 (HE, XUESONG) Mar 1, 2014 - Feb 29, 2024
    NIH
    Domestication and characterization of TM7-the most elusive oral phylum
    Role: Principal Investigator

Featured Content

Bibliographic
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Cen L, Chang Y, Bedree JK, Ma Y, Zhong Q, Utter DR, Dong PT, Lux R, Bor B, Liu J, McLean JS, Le S, He X. Exploitation of a Bacterium-Encoded Lytic Transglycosylase by a Human Oral Lytic Phage To Facilitate Infection. J Virol. 2022 09 14; 96(17):e0106322. PMID: 36000841; PMCID: PMC9472602.
    Citations:    Fields:    Translation:HumansCells
  2. Hendrickson EL, Bor B, Kerns KA, Lamont EI, Chang Y, Liu J, Cen L, Schulte F, Hardt M, Shi W, He X, McLean JS. Transcriptome of Epibiont Saccharibacteria Nanosynbacter lyticus Strain TM7x During the Establishment of Symbiosis. J Bacteriol. 2022 09 20; 204(9):e0011222. PMID: 35975994; PMCID: PMC9487520.
    Citations:    Fields:    Translation:HumansCells
  3. Liu J, Utter DR, Nie J, Kerns KA, Lamont EI, Hendrickson EL, Wang X, McLean JS, He X, Bor B. Draft Genome Sequences of Nine "Candidatus Nanosynbacter sp. HMT-352" Strains Cultured from the Human Oral Cavity. Microbiol Resour Announc. 2022 Aug 18; 11(8):e0040322. PMID: 35894623; PMCID: PMC9387224.
    Citations:    
  4. Dinis M, Traynor W, Agnello M, Sim MS, He X, Shi W, Lux R, Tran NC. Tooth-Specific Streptococcus mutans Distribution and Associated Microbiome. Microorganisms. 2022 May 31; 10(6). PMID: 35744648.
    Citations:    
  5. Le S, He X, Tong Y. Editorial: Phage Biology and Phage Therapy. Front Microbiol. 2022; 13:891848. PMID: 35531290; PMCID: PMC9073083.
    Citations:    
  6. Nie J, Utter DR, Kerns KA, Lamont EI, Hendrickson EL, Liu J, Wu T, He X, McLean J, Bor B. Strain-Level Variation and Diverse Host Bacterial Responses in Episymbiotic Saccharibacteria. mSystems. 2022 Apr 26; 7(2):e0148821. PMID: 35343799; PMCID: PMC9040727.
    Citations:    
  7. Dinis M, Agnello M, Cen L, Shokeen B, He X, Shi W, Wong DTW, Lux R, Tran NC. Oral Microbiome: Streptococcus mutans/Caries Concordant-Discordant Children. Front Microbiol. 2022; 13:782825. PMID: 35250921; PMCID: PMC8891984.
    Citations: 3     
  8. Tian J, Utter DR, Cen L, Dong PT, Shi W, Bor B, Qin M, McLean JS, He X. Acquisition of the arginine deiminase system benefits epiparasitic Saccharibacteria and their host bacteria in a mammalian niche environment. Proc Natl Acad Sci U S A. 2022 01 11; 119(2). PMID: 34992141; PMCID: PMC8764695.
    Citations: 3     Fields:    Translation:HumansAnimalsCells
  9. Botelho Dinis M, Agnello M, He X, Shi W, Chaichanasakul Tran N. Pilot study on selective antimicrobial effect of a halitosis mouthrinse: monospecies and saliva-derived microbiome in an in vitro model system. J Oral Microbiol. 2021; 13(1):1996755. PMID: 34745444; PMCID: PMC8567964.
    Citations:    
  10. Chipashvili O, Utter DR, Bedree JK, Ma Y, Schulte F, Mascarin G, Alayyoubi Y, Chouhan D, Hardt M, Bidlack F, Hasturk H, He X, McLean JS, Bor B. Episymbiotic Saccharibacteria suppresses gingival inflammation and bone loss in mice through host bacterial modulation. Cell Host Microbe. 2021 11 10; 29(11):1649-1662.e7. PMID: 34637779; PMCID: PMC8595704.
    Citations: 5     Fields:    Translation:HumansAnimalsCells
  11. Yang F, Dinis M, Haghighi F, He X, Shi W, Chaichanasakul Tran N. Oral colonization of Candida albicans and Streptococcus mutans in children with or without fixed orthodontic appliances: A pilot study. J Dent Sci. 2022 Jan; 17(1):451-458. PMID: 35028070; PMCID: PMC8739723.
    Citations: 1     
  12. Lyu X, Zheng H, Wang X, Zhang H, Gao L, Xun Z, Zhang Q, He X, Hua H, Yan Z, Chen F. Oral Microbiota Composition and Function Changes During Chronic Erythematous Candidiasis. Front Cell Infect Microbiol. 2021; 11:691092. PMID: 34490138.
    Citations: 1     Fields:    Translation:HumansCells
  13. Lamont EI, Gadkari A, Kerns KA, To TT, Daubert D, Kotsakis G, Bor B, He X, McLean JS. Modified SHI medium supports growth of a disease-state subgingival polymicrobial community in vitro. Mol Oral Microbiol. 2021 02; 36(1):37-49. PMID: 33174294; PMCID: PMC7984074.
    Citations: 3     Fields:    Translation:Humans
  14. Utter DR, He X, Cavanaugh CM, McLean JS, Bor B. The saccharibacterium TM7x elicits differential responses across its host range. ISME J. 2020 12; 14(12):3054-3067. PMID: 32839546; PMCID: PMC7784981.
    Citations: 12     Fields:    Translation:Cells
  15. Lamont EI, Hendrickson EL, McLean JS, He X, Bor B. Complete Genome Sequence of Strain BB001, a Novel Epibiont Bacterium from the Candidate Phylum Saccharibacteria (TM7). Microbiol Resour Announc. 2020 Aug 20; 9(34). PMID: 32816985.
    Citations: 1     
  16. McLean JS, Bor B, Kerns KA, Liu Q, To TT, Solden L, Hendrickson EL, Wrighton K, Shi W, He X. Acquisition and Adaptation of Ultra-small Parasitic Reduced Genome Bacteria to Mammalian Hosts. Cell Rep. 2020 07 21; 32(3):107939. PMID: 32698001.
    Citations: 20     Fields:    Translation:HumansAnimalsCellsPHPublic Health
  17. Liu T, Liu J, Liu J, Yang R, Lu X, He X, Shi W, Guo L. Interspecies Interactions Between Streptococcus Mutans and Streptococcus Agalactiae in vitro. Front Cell Infect Microbiol. 2020; 10:344. PMID: 32733820.
    Citations: 2     Fields:    Translation:HumansCells
  18. Tian J, Shi W, Xu H, Wang G, He X, Chen F, Qin M. Differences in Sole Carbon Source Utilization of the Dental Plaque Microbiota Between Caries-Free and Caries-Affected Children. Front Microbiol. 2020; 11:458. PMID: 32265883.
    Citations:    
  19. Yang Y, Shen W, Zhong Q, Chen Q, He X, Baker JL, Xiong K, Jin X, Wang J, Hu F, Le S. Development of a Bacteriophage Cocktail to Constrain the Emergence of Phage-Resistant Pseudomonas aeruginosa. Front Microbiol. 2020; 11:327. PMID: 32194532.
    Citations: 29     
  20. Lin J, Dinis M, Tseng CH, Agnello M, He X, Silva DR, Tran NC. Effectiveness of the GumChucks flossing system compared to string floss for interdental plaque removal in children: a randomized clinical trial. Sci Rep. 2020 02 20; 10(1):3052. PMID: 32080218.
    Citations: 1     Fields:    Translation:HumansPHPublic Health
  21. Chen Y, Agnello M, Dinis M, Chien KC, Wang J, Hu W, Shi W, He X, Zou J. Lollipop containing Glycyrrhiza uralensis extract reduces Streptococcus mutans colonization and maintains oral microbial diversity in Chinese preschool children. PLoS One. 2019; 14(8):e0221756. PMID: 31442287.
    Citations: 5     Fields:    Translation:HumansAnimalsCellsCTClinical Trials
  22. Baker JL, Hendrickson EL, Tang X, Lux R, He X, Edlund A, McLean JS, Shi W. Klebsiella and Providencia emerge as lone survivors following long-term starvation of oral microbiota. Proc Natl Acad Sci U S A. 2019 04 23; 116(17):8499-8504. PMID: 30975748.
    Citations: 16     Fields:    Translation:HumansCells
  23. Edlund A, Yang Y, Yooseph S, He X, Shi W, McLean JS. Uncovering complex microbiome activities via metatranscriptomics during 24?hours of oral biofilm assembly and maturation. Microbiome. 2018 12 06; 6(1):217. PMID: 30522530.
    Citations: 13     Fields:    Translation:HumansCells
  24. Bor B, McLean JS, Foster KR, Cen L, To TT, Serrato-Guillen A, Dewhirst FE, Shi W, He X. Rapid evolution of decreased host susceptibility drives a stable relationship between ultrasmall parasite TM7x and its bacterial host. Proc Natl Acad Sci U S A. 2018 11 27; 115(48):12277-12282. PMID: 30442671.
    Citations: 23     Fields:    Translation:HumansCells
  25. Bedree JK, Bor B, Cen L, Edlund A, Lux R, McLean JS, Shi W, He X. Quorum Sensing Modulates the Epibiotic-Parasitic Relationship Between Actinomyces odontolyticus and Its Saccharibacteria epibiont, a Nanosynbacter lyticus Strain, TM7x. Front Microbiol. 2018; 9:2049. PMID: 30319555.
    Citations: 12     
  26. Xu H, Tian J, Hao W, Zhang Q, Zhou Q, Shi W, Qin M, He X, Chen F. Oral Microbiome Shifts From Caries-Free to Caries-Affected Status in 3-Year-Old Chinese Children: A Longitudinal Study. Front Microbiol. 2018; 9:2009. PMID: 30210479.
    Citations: 21     
  27. Shen M, Yang Y, Shen W, Cen L, McLean JS, Shi W, Le S, He X. A Linear Plasmid-Like Prophage of Actinomyces odontolyticus Promotes Biofilm Assembly. Appl Environ Microbiol. 2018 09 01; 84(17). PMID: 29915115.
    Citations: 12     Fields:    Translation:HumansCells
  28. Shen M, Zhang H, Shen W, Zou Z, Lu S, Li G, He X, Agnello M, Shi W, Hu F, Le S. Pseudomonas aeruginosa MutL promotes large chromosomal deletions through non-homologous end joining to prevent bacteriophage predation. Nucleic Acids Res. 2018 05 18; 46(9):4505-4514. PMID: 29514250.
    Citations: 22     Fields:    Translation:Cells
  29. Yang Y, Reipa V, Liu G, Meng Y, Wang X, Mineart KP, Prabhu VM, Shi W, Lin NJ, He X, Sun J. pH-Sensitive Compounds for Selective Inhibition of Acid-Producing Bacteria. ACS Appl Mater Interfaces. 2018 Mar 14; 10(10):8566-8573. PMID: 29436821.
    Citations: 6     Fields:    Translation:Cells
  30. Edlund A, Garg N, Mohimani H, Gurevich A, He X, Shi W, Dorrestein PC, McLean JS. Metabolic Fingerprints from the Human Oral Microbiome Reveal a Vast Knowledge Gap of Secreted Small Peptidic Molecules. mSystems. 2017 Jul-Aug; 2(4). PMID: 28761934.
    Citations: 14     
  31. Zhao X, Shen M, Jiang X, Shen W, Zhong Q, Yang Y, Tan Y, Agnello M, He X, Hu F, Le S. Transcriptomic and Metabolomics Profiling of Phage-Host Interactions between Phage PaP1 and Pseudomonas aeruginosa. Front Microbiol. 2017; 8:548. PMID: 28421049.
    Citations: 16     
  32. Guo L, Shokeen B, He X, Shi W, Lux R. Streptococcus mutans SpaP binds to RadD of Fusobacterium nucleatum ssp. polymorphum. Mol Oral Microbiol. 2017 10; 32(5):355-364. PMID: 27976528.
    Citations: 20     Fields:    Translation:HumansCells
  33. Baker JL, Bor B, Agnello M, Shi W, He X. Ecology of the Oral Microbiome: Beyond Bacteria. Trends Microbiol. 2017 05; 25(5):362-374. PMID: 28089325.
    Citations: 94     Fields:    Translation:HumansAnimalsCells
  34. Shi B, Wu T, McLean J, Edlund A, Young Y, He X, Lv H, Zhou X, Shi W, Li H, Lux R. The Denture-Associated Oral Microbiome in Health and Stomatitis. mSphere. 2016 Nov-Dec; 1(6). PMID: 28066812; PMCID: PMC5196032.
    Citations: 19     Fields:    
  35. Bor B, Cen L, Agnello M, Shi W, He X. Morphological and physiological changes induced by contact-dependent interaction between Candida albicans and Fusobacterium nucleatum. Sci Rep. 2016 06 14; 6:27956. PMID: 27295972.
    Citations: 29     Fields:    Translation:AnimalsCells
  36. Liu L, Zhang Q, Lin J, Ma L, Zhou Z, He X, Jia Y, Chen F. Investigating Oral Microbiome Profiles in Children with Cleft Lip and Palate for Prognosis of Alveolar Bone Grafting. PLoS One. 2016; 11(5):e0155683. PMID: 27191390.
    Citations: 2     Fields:    Translation:Humans
  37. Deriu E, Boxx GM, He X, Pan C, Benavidez SD, Cen L, Rozengurt N, Shi W, Cheng G. Influenza Virus Affects Intestinal Microbiota and Secondary Salmonella Infection in the Gut through Type I Interferons. PLoS Pathog. 2016 05; 12(5):e1005572. PMID: 27149619.
    Citations: 112     Fields:    Translation:Animals
  38. Ren W, Xun Z, Wang Z, Zhang Q, Liu X, Zheng H, Zhang Q, Zhang Y, Zhang L, Wu C, Zheng S, Qin N, Ehrlich SD, Li Y, He X, Xu T, Chen T, Chen F. Tongue Coating and the Salivary Microbial Communities Vary in Children with Halitosis. Sci Rep. 2016 Apr 15; 6:24481. PMID: 27080513.
    Citations: 14     Fields:    Translation:Humans
  39. Edlund A, Liu Q, Watling M, To TT, Bumgarner RE, He X, Shi W, McLean JS. High-Quality Draft Genome Sequence of Low-pH-Active Veillonella parvula Strain SHI-1, Isolated from Human Saliva within an In Vitro Oral Biofilm Model. Genome Announc. 2016 Feb 18; 4(1). PMID: 26893419.
    Citations: 1     
  40. McLean JS, Liu Q, Bor B, Bedree JK, Cen L, Watling M, To TT, Bumgarner RE, He X, Shi W. Draft Genome Sequence of Actinomyces odontolyticus subsp. actinosynbacter Strain XH001, the Basibiont of an Oral TM7 Epibiont. Genome Announc. 2016 Feb 04; 4(1). PMID: 26847892.
    Citations: 11     
  41. Guo L, McLean JS, Lux R, He X, Shi W. The well-coordinated linkage between acidogenicity and aciduricity via insoluble glucans on the surface of Streptococcus mutans. Sci Rep. 2015 Dec 10; 5:18015. PMID: 26657939.
    Citations: 29     Fields:    Translation:Cells
  42. Bor B, Poweleit N, Bois JS, Cen L, Bedree JK, Zhou ZH, Gunsalus RP, Lux R, McLean JS, He X, Shi W. Phenotypic and Physiological Characterization of the Epibiotic Interaction Between TM7x and Its Basibiont Actinomyces. Microb Ecol. 2016 Jan; 71(1):243-55. PMID: 26597961.
    Citations: 27     Fields:    Translation:HumansCells
  43. Guo L, McLean JS, Yang Y, Eckert R, Kaplan CW, Kyme P, Sheikh O, Varnum B, Lux R, Shi W, He X. Precision-guided antimicrobial peptide as a targeted modulator of human microbial ecology. Proc Natl Acad Sci U S A. 2015 Jun 16; 112(24):7569-74. PMID: 26034276.
    Citations: 60     Fields:    Translation:HumansCells
  44. Edlund A, Yang Y, Yooseph S, Hall AP, Nguyen DD, Dorrestein PC, Nelson KE, He X, Lux R, Shi W, McLean JS. Meta-omics uncover temporal regulation of pathways across oral microbiome genera during in vitro sugar metabolism. ISME J. 2015 Dec; 9(12):2605-19. PMID: 26023872.
    Citations: 34     Fields:    Translation:HumansCells
  45. Wu T, He X, Lu H, Bradshaw DJ, Axe A, Loewy Z, Liu H, Shi W, Lux R. Development of In Vitro Denture Biofilm Models for Halitosis Related Bacteria and their Application in Testing the Efficacy of Antimicrobial Agents. Open Dent J. 2015; 9:125-31. PMID: 25926895.
    Citations: 4     
  46. He X, McLean JS, Edlund A, Yooseph S, Hall AP, Liu SY, Dorrestein PC, Esquenazi E, Hunter RC, Cheng G, Nelson KE, Lux R, Shi W. Cultivation of a human-associated TM7 phylotype reveals a reduced genome and epibiotic parasitic lifestyle. Proc Natl Acad Sci U S A. 2015 Jan 06; 112(1):244-9. PMID: 25535390; PMCID: PMC4291631.
    Citations: 176     Fields:    Translation:HumansAnimalsCells
  47. Guo L, He X, Shi W. Intercellular communications in multispecies oral microbial communities. Front Microbiol. 2014; 5:328. PMID: 25071741.
    Citations: 23     
  48. Le S, Yao X, Lu S, Tan Y, Rao X, Li M, Jin X, Wang J, Zhao Y, Wu NC, Lux R, He X, Shi W, Hu F. Chromosomal DNA deletion confers phage resistance to Pseudomonas aeruginosa. Sci Rep. 2014 Apr 28; 4:4738. PMID: 24770387.
    Citations: 40     Fields:    Translation:AnimalsCells
  49. Kaplan A, Kaplan CW, He X, McHardy I, Shi W, Lux R. Characterization of aid1, a novel gene involved in Fusobacterium nucleatum interspecies interactions. Microb Ecol. 2014 Aug; 68(2):379-87. PMID: 24643713.
    Citations: 28     Fields:    Translation:Cells
  50. He X, McLean JS, Guo L, Lux R, Shi W. The social structure of microbial community involved in colonization resistance. ISME J. 2014 Mar; 8(3):564-574. PMID: 24088624.
    Citations: 42     Fields:    Translation:AnimalsCells
  51. Edlund A, Yang Y, Hall AP, Guo L, Lux R, He X, Nelson KE, Nealson KH, Yooseph S, Shi W, McLean JS. An in vitro biofilm model system maintaining a highly reproducible species and metabolic diversity approaching that of the human oral microbiome. Microbiome. 2013 Oct 02; 1(1):25. PMID: 24451062.
    Citations: 66     Fields:    
  52. Le S, He X, Tan Y, Huang G, Zhang L, Lux R, Shi W, Hu F. Mapping the tail fiber as the receptor binding protein responsible for differential host specificity of Pseudomonas aeruginosa bacteriophages PaP1 and JG004. PLoS One. 2013; 8(7):e68562. PMID: 23874674.
    Citations: 51     Fields:    Translation:Cells
  53. Pan H, He X, Lux R, Luan J, Shi W. Killing of Escherichia coli by Myxococcus xanthus in aqueous environments requires exopolysaccharide-dependent physical contact. Microb Ecol. 2013 Oct; 66(3):630-8. PMID: 23828520.
    Citations: 7     Fields:    Translation:Cells
  54. Guo L, Hu W, He X, Lux R, McLean J, Shi W. investigating acid production by Streptococcus mutans with a surface-displayed pH-sensitive green fluorescent protein. PLoS One. 2013; 8(2):e57182. PMID: 23468929.
    Citations: 23     Fields:    Translation:HumansCells
  55. Hu W, Li L, Sharma S, Wang J, McHardy I, Lux R, Yang Z, He X, Gimzewski JK, Li Y, Shi W. DNA builds and strengthens the extracellular matrix in Myxococcus xanthus biofilms by interacting with exopolysaccharides. PLoS One. 2012; 7(12):e51905. PMID: 23300576.
    Citations: 28     Fields:    Translation:Cells
  56. Pan H, Luan J, He X, Lux R, Shi W. The clpB gene is involved in the stress response of Myxococcus xanthus during vegetative growth and development. Microbiology (Reading). 2012 Sep; 158(Pt 9):2336-2343. PMID: 22790397.
    Citations: 4     Fields:    Translation:Cells
  57. Wang R, Kaplan A, Guo L, Shi W, Zhou X, Lux R, He X. The influence of iron availability on human salivary microbial community composition. Microb Ecol. 2012 Jul; 64(1):152-61. PMID: 22318873.
    Citations: 16     Fields:    Translation:HumansCells
  58. He X, Hu W, Kaplan CW, Guo L, Shi W, Lux R. Adherence to streptococci facilitates Fusobacterium nucleatum integration into an oral microbial community. Microb Ecol. 2012 Apr; 63(3):532-42. PMID: 22202886.
    Citations: 23     Fields:    Translation:HumansAnimalsCells
  59. Hu W, Yang Z, Lux R, Zhao M, Wang J, He X, Shi W. Direct visualization of the interaction between pilin and exopolysaccharides of Myxococcus xanthus with eGFP-fused PilA protein. FEMS Microbiol Lett. 2012 Jan; 326(1):23-30. PMID: 22092602.
    Citations: 11     Fields:    Translation:Cells
  60. Chugal N, Wang JK, Wang R, He X, Kang M, Li J, Zhou X, Shi W, Lux R. Molecular characterization of the microbial flora residing at the apical portion of infected root canals of human teeth. J Endod. 2011 Oct; 37(10):1359-64. PMID: 21924182.
    Citations: 8     Fields:    Translation:HumansCells
  61. Wang J, Hu W, Lux R, He X, Li Y, Shi W. Natural transformation of Myxococcus xanthus. J Bacteriol. 2011 May; 193(9):2122-32. PMID: 21378184.
    Citations: 11     Fields:    Translation:Cells
  62. He X, Tian Y, Guo L, Lux R, Zusman DR, Shi W. Oral-derived bacterial flora defends its domain by recognizing and killing intruders--a molecular analysis using Escherichia coli as a model intestinal bacterium. Microb Ecol. 2010 Oct; 60(3):655-64. PMID: 20625713.
    Citations: 19     Fields:    Translation:AnimalsCells
  63. He X, Tian Y, Guo L, Ano T, Lux R, Zusman DR, Shi W. In vitro communities derived from oral and gut microbial floras inhibit the growth of bacteria of foreign origins. Microb Ecol. 2010 Oct; 60(3):665-76. PMID: 20625712.
    Citations: 16     Fields:    Translation:AnimalsCells
  64. He X, Wu C, Yarbrough D, Sim L, Niu G, Merritt J, Shi W, Qi F. The cia operon of Streptococcus mutans encodes a unique component required for calcium-mediated autoregulation. Mol Microbiol. 2008 Oct; 70(1):112-26. PMID: 18681938.
    Citations: 24     Fields:    Translation:HumansCells
  65. Kuramitsu HK, He X, Lux R, Anderson MH, Shi W. Interspecies interactions within oral microbial communities. Microbiol Mol Biol Rev. 2007 Dec; 71(4):653-70. PMID: 18063722; PMCID: PMC2168648.
    Citations: 210     Fields:    Translation:HumansCells
  66. He X, Bhateja M, Fuqua C. Promoter-probe cassettes with the gusA (beta-glucuronidase) reporter gene and several different antibiotic resistance markers. J Microbiol Methods. 2005 Feb; 60(2):281-3. PMID: 15590103.
    Citations: 1     Fields:    Translation:Cells
  67. He X, Chang W, Pierce DL, Seib LO, Wagner J, Fuqua C. Quorum sensing in Rhizobium sp. strain NGR234 regulates conjugal transfer (tra) gene expression and influences growth rate. J Bacteriol. 2003 Feb; 185(3):809-22. PMID: 12533456.
    Citations: 46     Fields:    Translation:Cells
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.