Harvard Catalyst Profiles

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Kun Hu, Ph.D.

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Research
The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
  1. RF1AG064312 (HU, KUN) Sep 1, 2019 - Mar 31, 2024
    NIH/NIA
    Integrative Motor Activity Biomarker for the Risk of Alzheimer's Risk
    Role: Principal Investigator
  2. R01AG059867 (HU, KUN) Aug 15, 2018 - Apr 30, 2023
    NIH/NIA
    Fractal motor activity regulation and the risk for Alzheimers disease in middle-to-old aged adults
    Role: Principal Investigator
  3. R01AG048108 (HU, KUN) Sep 1, 2015 - Apr 30, 2019
    NIH/NIA
    Neuropathology for disrupted multiscale activity control in Alzheimer's disease
    Role: Principal Investigator
  4. R00HL102241 (HU, KUN) Apr 1, 2010 - Mar 31, 2015
    NIH/NHLBI
    Fractal Regulatory Function of the Circadian System
    Role: Principal Investigator
  5. K99HL102241 (HU, KUN) Apr 1, 2010 - Mar 31, 2012
    NIH/NHLBI
    Fractal Regulatory Function of the Circadian System
    Role: Principal Investigator

Bibliographic
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Qian J, Scheer FA, Hu K, Shea SA. The circadian system modulates the rate of recovery of systolic blood pressure after exercise in humans. Sleep. 2020 Apr 15; 43(4). PMID: 31616941.
    Citations:    
  2. Li P, Lim ASP, Gao L, Hu C, Yu L, Bennett DA, Buchman AS, Hu K. More random motor activity fluctuations predict incident frailty, disability, and mortality. Sci Transl Med. 2019 10 30; 11(516). PMID: 31666398.
    Citations:    
  3. Li P, Yu L, Yang J, Lo MT, Hu C, Buchman AS, Bennett DA, Hu K. Interaction between the progression of Alzheimer's disease and fractal degradation. Neurobiol Aging. 2019 11; 83:21-30. PMID: 31585364.
    Citations:    
  4. Liu J, Chen L, Tu Y, Chen X, Hu K, Tu Y, Lin M, Xie G, Chen S, Huang J, Liu W, Wu J, Xiao T, Wilson G, Lang C, Park J, Tao J, Kong J. Different exercise modalities relieve pain syndrome in patients with knee osteoarthritis and modulate the dorsolateral prefrontal cortex: A multiple mode MRI study. Brain Behav Immun. 2019 Nov; 82:253-263. PMID: 31472246.
    Citations:    
  5. Liu J, Chen L, Chen X, Hu K, Tu Y, Lin M, Huang J, Liu W, Wu J, Qiu Z, Zhu J, Li M, Park J, Wilson G, Lang C, Xie G, Tao J, Kong J. Modulatory effects of different exercise modalities on the functional connectivity of the periaqueductal grey and ventral tegmental area in patients with knee osteoarthritis: a randomised multimodal magnetic resonance imaging study. Br J Anaesth. 2019 Oct; 123(4):506-518. PMID: 31395306.
    Citations:    
  6. Sun W, Li G, Lai Z, Lu Z, Lin Y, Peng J, Huang J, Hu K. Subacute Combined Degeneration of the Spinal Cord and Hydrocephalus Associated with Vitamin B12 Deficiency. World Neurosurg. 2019 Aug; 128:277-283. PMID: 31082549.
    Citations:    
  7. Gao L, Li P, Hu C, To T, Patxot M, Falvey B, Wong PM, Scheer FAJL, Lin C, Lo MT, Hu K. Nocturnal heart rate variability moderates the association between sleep-wake regularity and mood in young adults. Sleep. 2019 05 01; 42(5). PMID: 30722058.
    Citations:    
  8. Tang Y, Zhao ZZ, Hu K, Feng T, Li ZH, Chen HP, Liu JK. Irpexolidal Represents a Class of Triterpenoid from the Fruiting Bodies of the Medicinal Fungus Irpex lacteus. J Org Chem. 2019 02 15; 84(4):1845-1852. PMID: 30673259.
    Citations:    
  9. Scheer FAJL, Chellappa SL, Hu K, Shea SA. Impact of mental stress, the circadian system and their interaction on human cardiovascular function. Psychoneuroendocrinology. 2019 05; 103:125-129. PMID: 30682628.
    Citations:    Fields:    
  10. Wu JQ, Li P, Stavitsky Gilbert K, Hu K, Cronin-Golomb A. Circadian Rest-Activity Rhythms Predict Cognitive Function in Early Parkinson's Disease Independently of Sleep. Mov Disord Clin Pract. 2018 Nov-Dec; 5(6):614-619. PMID: 30637282.
    Citations:    
  11. Pittman-Polletta B, Hu K, Kocsis B. Subunit-specific NMDAR antagonism dissociates schizophrenia subtype-relevant oscillopathies associated with frontal hypofunction and hippocampal hyperfunction. Sci Rep. 2018 08 02; 8(1):11588. PMID: 30072757.
    Citations:    Fields:    
  12. Wang YH, Hu K, Lo MT. Uniform Phase Empirical Mode Decomposition: An Optimal Hybridization of Masking Signal and Ensemble Approaches. IEEE Access. 2018; 6:34819-34833. PMID: 31106103.
    Citations:    
  13. Li P, Yu L, Lim ASP, Buchman AS, Scheer FAJL, Shea SA, Schneider JA, Bennett DA, Hu K. Fractal regulation and incident Alzheimer's disease in elderly individuals. Alzheimers Dement. 2018 09; 14(9):1114-1125. PMID: 29733807.
    Citations:    Fields:    
  14. Hu K, Shen S, Zhang L. Herniation of crypts in hyperplastic polyp and sessile serrated adenoma: a prospective study. Am J Cancer Res. 2018; 8(1):144-153. PMID: 29416927.
    Citations:    
  15. Tao J, Chen X, Liu J, Egorova N, Xue X, Liu W, Zheng G, Li M, Wu J, Hu K, Wang Z, Chen L, Kong J. Tai Chi Chuan and Baduanjin Mind-Body Training Changes Resting-State Low-Frequency Fluctuations in the Frontal Lobe of Older Adults: A Resting-State fMRI Study. Front Hum Neurosci. 2017; 11:514. PMID: 29163096.
    Citations:    
  16. Zhang X, Li B, Hu K, Wan Q, Ding Y, Vanwanseele B. Adding an arch support to a heel lift improves stability and comfort during gait. Gait Posture. 2017 10; 58:94-97. PMID: 28763715.
    Citations:    Fields:    Translation:Humans
  17. Shen S, Lim G, You Z, Ding W, Huang P, Ran C, Doheny J, Caravan P, Tate S, Hu K, Kim H, McCabe M, Huang B, Xie Z, Kwon D, Chen L, Mao J. Gut microbiota is critical for the induction of chemotherapy-induced pain. Nat Neurosci. 2017 Sep; 20(9):1213-1216. PMID: 28714953.
    Citations: 4     Fields:    Translation:AnimalsCells
  18. Li P, Morris CJ, Patxot M, Yugay T, Mistretta J, Purvis TE, Scheer FAJL, Hu K. Reduced Tolerance to Night Shift in Chronic Shift Workers: Insight From Fractal Regulation. Sleep. 2017 07 01; 40(7). PMID: 28838129.
    Citations:    Fields:    Translation:Humans
  19. Morris CJ, Purvis TE, Mistretta J, Hu K, Scheer FAJL. Circadian Misalignment Increases C-Reactive Protein and Blood Pressure in Chronic Shift Workers. J Biol Rhythms. 2017 04; 32(2):154-164. PMID: 28347188.
    Citations: 5     Fields:    Translation:Humans
  20. Li P, To T, Chiang WY, Escobar C, Buijs RM, Hu K. Fractal Regulation in Temporal Activity Fluctuations: A Biomarker for Circadian Control and Beyond. JSM Biomark. 2017; 3(1). PMID: 28553673.
    Citations:    
  21. Tao J, Liu J, Liu W, Huang J, Xue X, Chen X, Wu J, Zheng G, Chen B, Li M, Sun S, Jorgenson K, Lang C, Hu K, Chen S, Chen L, Kong J. Tai Chi Chuan and Baduanjin Increase Grey Matter Volume in Older Adults: A Brain Imaging Study. J Alzheimers Dis. 2017; 60(2):389-400. PMID: 28869478.
    Citations:    
  22. Hu K, Sonti S, Glaser ST, Duclos RI, Gatley SJ. Brain uptake and metabolism of the endocannabinoid anandamide labeled in either the arachidonoyl or ethanolamine moiety. Nucl Med Biol. 2017 02; 45:43-50. PMID: 27889577.
    Citations:    Fields:    Translation:Animals
  23. Lin C, Chang YC, Cheng YC, Lai PJ, Yeh CH, Hsieh WH, Hu K, Wu JT, Lee HH, Lo MT, Ho YL. Probing the Fractal Pattern of Heartbeats in Drosophila Pupae by Visible Optical Recording System. Sci Rep. 2016 08 18; 6:31950. PMID: 27535299.
    Citations:    Fields:    Translation:AnimalsCells
  24. Yeh CH, Lo MT, Hu K. Spurious cross-frequency amplitude-amplitude coupling in nonstationary, nonlinear signals. Physica A. 2016 Jul 15; 454:143-150. PMID: 27103757.
    Citations: 3     
  25. Hu K, Riemersma-van der Lek RF, Patxot M, Li P, Shea SA, Scheer FA, Van Someren EJ. Progression of Dementia Assessed by Temporal Correlations of Physical Activity: Results From a 3.5-Year, Longitudinal Randomized Controlled Trial. Sci Rep. 2016 06 13; 6:27742. PMID: 27292543.
    Citations: 2     Fields:    Translation:Humans
  26. Lo MT, Chiang WY, Hsieh WH, Escobar C, Buijs RM, Hu K. Interactive Effects of Dorsomedial Hypothalamic Nucleus and Time-Restricted Feeding on Fractal Motor Activity Regulation. Front Physiol. 2016; 7:174. PMID: 27242548.
    Citations: 2     
  27. Huang NE, Hu K, Yang AC, Chang HC, Jia D, Liang WK, Yeh JR, Kao CL, Juan CH, Peng CK, Meijer JH, Wang YH, Long SR, Wu Z. On Holo-Hilbert spectral analysis: a full informational spectral representation for nonlinear and non-stationary data. Philos Trans A Math Phys Eng Sci. 2016 Apr 13; 374(2065):20150206. PMID: 26953180.
    Citations: 4     Fields:    
  28. Morris CJ, Purvis TE, Hu K, Scheer FA. Circadian misalignment increases cardiovascular disease risk factors in humans. Proc Natl Acad Sci U S A. 2016 Mar 08; 113(10):E1402-11. PMID: 26858430.
    Citations: 39     Fields:    Translation:Humans
  29. Chen MC, Chiang WY, Yugay T, Patxot M, Özçivit IB, Hu K, Lu J. Anterior Insula Regulates Multiscale Temporal Organization of Sleep and Wake Activity. J Biol Rhythms. 2016 Apr; 31(2):182-93. PMID: 26825619.
    Citations:    Fields:    Translation:Animals
  30. Gong YS, Guo J, Hu K, Gao YQ, Xie BJ, Sun ZD, Yang EN, Hou FL. Ameliorative effect of lotus seedpod proanthocyanidins on cognitive impairment and brain aging induced by D-galactose. Exp Gerontol. 2016 Feb; 74:21-8. PMID: 26657492.
    Citations: 3     Fields:    Translation:AnimalsCells
  31. Yeh CH, Hung CY, Wang YH, Hsu WT, Chang YC, Yeh JR, Lee PL, Hu K, Kang JH, Lo MT. Novel application of a Wii remote to measure spasticity with the pendulum test: Proof of concept. Gait Posture. 2016 Jan; 43:70-5. PMID: 26669955.
    Citations: 2     Fields:    Translation:HumansCTClinical Trials
  32. Holmes ML, Manor B, Hsieh WH, Hu K, Lipsitz LA, Li L. Tai Chi training reduced coupling between respiration and postural control. Neurosci Lett. 2016 Jan 01; 610:60-5. PMID: 26518241.
    Citations: 1     Fields:    Translation:Humans
  33. Wang JL, Lim AS, Chiang WY, Hsieh WH, Lo MT, Schneider JA, Buchman AS, Bennett DA, Hu K, Saper CB. Suprachiasmatic neuron numbers and rest-activity circadian rhythms in older humans. Ann Neurol. 2015 Aug; 78(2):317-22. PMID: 25921596.
    Citations: 25     Fields:    Translation:HumansCells
  34. Lo MT, Chang YC, Lin C, Young HW, Lin YH, Ho YL, Peng CK, Hu K. Outlier-resilient complexity analysis of heartbeat dynamics. Sci Rep. 2015 Mar 06; 5:8836. PMID: 25744292.
    Citations: 5     Fields:    Translation:Humans
  35. Gu C, Coomans CP, Hu K, Scheer FA, Stanley HE, Meijer JH. Lack of exercise leads to significant and reversible loss of scale invariance in both aged and young mice. Proc Natl Acad Sci U S A. 2015 Feb 24; 112(8):2320-4. PMID: 25675516.
    Citations: 9     Fields:    Translation:HumansAnimals
  36. Hsieh WH, Escobar C, Yugay T, Lo MT, Pittman-Polletta B, Salgado-Delgado R, Scheer FA, Shea SA, Buijs RM, Hu K. Simulated shift work in rats perturbs multiscale regulation of locomotor activity. J R Soc Interface. 2014 Jul 06; 11(96). PMID: 24829282.
    Citations: 10     Fields:    Translation:Animals
  37. Kaufman J, Lessler J, Harry A, Edlund S, Hu K, Douglas J, Thoens C, Appel B, Käsbohrer A, Filter M. A likelihood-based approach to identifying contaminated food products using sales data: performance and challenges. PLoS Comput Biol. 2014 Jul; 10(7):e1003692. PMID: 24992565.
    Citations: 1     Fields:    Translation:HumansPHPublic Health
  38. Hu K, Cheng G, Zhang H, Wang H, Ruan J, Chen L, Fang W, Yang X. Relationship between permeability glycoprotein (P-gp) gene expression and enrofloxacin metabolism in Nile Tilapia. J Aquat Anim Health. 2014 Jun; 26(2):59-65. PMID: 24895858.
    Citations:    
  39. Pittman-Polletta B, Hsieh WH, Kaur S, Lo MT, Hu K. Detecting phase-amplitude coupling with high frequency resolution using adaptive decompositions. J Neurosci Methods. 2014 Apr 15; 226:15-32. PMID: 24452055.
    Citations: 8     Fields:    Translation:Animals
  40. Zhong N, Gui Z, Xu L, Huang J, Hu K, Gao Y, Zhang X, Xu Z, Su J, Li B. Solvent-free enzymatic synthesis of 1, 3-diacylglycerols by direct esterification of glycerol with saturated fatty acids. Lipids Health Dis. 2013 May 08; 12:65. PMID: 23656739.
    Citations:    
  41. Zhou J, Manor B, Liu D, Hu K, Zhang J, Fang J. The complexity of standing postural control in older adults: a modified detrended fluctuation analysis based upon the empirical mode decomposition algorithm. PLoS One. 2013; 8(5):e62585. PMID: 23650518.
    Citations: 4     Fields:    Translation:Humans
  42. Pittman-Polletta BR, Scheer FA, Butler MP, Shea SA, Hu K. The role of the circadian system in fractal neurophysiological control. Biol Rev Camb Philos Soc. 2013 Nov; 88(4):873-94. PMID: 23573942.
    Citations: 14     Fields:    Translation:Animals
  43. Hu K, Harper DG, Shea SA, Stopa EG, Scheer FA. Noninvasive fractal biomarker of clock neurotransmitter disturbance in humans with dementia. Sci Rep. 2013; 3:2229. PMID: 23863985.
    Citations: 12     Fields:    Translation:HumansCells
  44. Hu K, Meijer JH, Shea SA, vanderLeest HT, Pittman-Polletta B, Houben T, van Oosterhout F, Deboer T, Scheer FA. Fractal patterns of neural activity exist within the suprachiasmatic nucleus and require extrinsic network interactions. PLoS One. 2012; 7(11):e48927. PMID: 23185285.
    Citations: 11     Fields:    Translation:AnimalsCells
  45. Aoi MC, Hu K, Lo MT, Selim M, Olufsen MS, Novak V. Impaired cerebral autoregulation is associated with brain atrophy and worse functional status in chronic ischemic stroke. PLoS One. 2012; 7(10):e46794. PMID: 23071639.
    Citations: 9     Fields:    Translation:Humans
  46. Hu K, Lo MT, Peng CK, Liu Y, Novak V. A nonlinear dynamic approach reveals a long-term stroke effect on cerebral blood flow regulation at multiple time scales. PLoS Comput Biol. 2012; 8(7):e1002601. PMID: 22807666.
    Citations: 10     Fields:    Translation:Humans
  47. Manor BD, Hu K, Peng CK, Lipsitz LA, Novak V. Posturo-respiratory synchronization: effects of aging and stroke. Gait Posture. 2012 Jun; 36(2):254-9. PMID: 22475726.
    Citations: 4     Fields:    Translation:HumansCells
  48. Jeyaraj D, Haldar SM, Wan X, McCauley MD, Ripperger JA, Hu K, Lu Y, Eapen BL, Sharma N, Ficker E, Cutler MJ, Gulick J, Sanbe A, Robbins J, Demolombe S, Kondratov RV, Shea SA, Albrecht U, Wehrens XH, Rosenbaum DS, Jain MK. Circadian rhythms govern cardiac repolarization and arrhythmogenesis. Nature. 2012 Feb 22; 483(7387):96-9. PMID: 22367544.
    Citations: 95     Fields:    Translation:AnimalsCells
  49. Rissanen SM, Kankaanpää M, Tarvainen MP, Novak V, Novak P, Hu K, Manor B, Airaksinen O, Karjalainen PA. Analysis of EMG and acceleration signals for quantifying the effects of deep brain stimulation in Parkinson's disease. IEEE Trans Biomed Eng. 2011 Sep; 58(9):2545-53. PMID: 21672674.
    Citations: 5     Fields:    Translation:Humans
  50. Shea SA, Hilton MF, Hu K, Scheer FA. Existence of an endogenous circadian blood pressure rhythm in humans that peaks in the evening. Circ Res. 2011 Apr 15; 108(8):980-4. PMID: 21474818.
    Citations: 33     Fields:    Translation:Humans
  51. Hu K, Scheer FA, Laker M, Smales C, Shea SA. Endogenous circadian rhythm in vasovagal response to head-up tilt. Circulation. 2011 Mar 08; 123(9):961-70. PMID: 21339480.
    Citations: 19     Fields:    Translation:Humans
  52. Scheer FA, Hu K, Evoniuk H, Kelly EE, Malhotra A, Hilton MF, Shea SA. Impact of the human circadian system, exercise, and their interaction on cardiovascular function. Proc Natl Acad Sci U S A. 2010 Nov 23; 107(47):20541-6. PMID: 21059915.
    Citations: 67     Fields:    Translation:Humans
  53. Manor B, Costa MD, Hu K, Newton E, Starobinets O, Kang HG, Peng CK, Novak V, Lipsitz LA. Physiological complexity and system adaptability: evidence from postural control dynamics of older adults. J Appl Physiol (1985). 2010 Dec; 109(6):1786-91. PMID: 20947715.
    Citations: 48     Fields:    Translation:Humans
  54. Lin LY, Lo MT, Ko PC, Lin C, Chiang WC, Liu YB, Hu K, Lin JL, Chen WJ, Ma MH. Detrended fluctuation analysis predicts successful defibrillation for out-of-hospital ventricular fibrillation cardiac arrest. Resuscitation. 2010 Mar; 81(3):297-301. PMID: 20071067.
    Citations: 11     Fields:    Translation:Humans
  55. Novak V, Hu K, Desrochers L, Novak P, Caplan L, Lipsitz L, Selim M. Cerebral flow velocities during daily activities depend on blood pressure in patients with chronic ischemic infarctions. Stroke. 2010 Jan; 41(1):61-6. PMID: 19959536.
    Citations: 9     Fields:    Translation:Humans
  56. Lo MT, Novak V, Peng CK, Liu Y, Hu K. Nonlinear phase interaction between nonstationary signals: a comparison study of methods based on Hilbert-Huang and Fourier transforms. Phys Rev E Stat Nonlin Soft Matter Phys. 2009 Jun; 79(6 Pt 1):061924. PMID: 19658541.
    Citations: 21     Fields:    Translation:HumansAnimalsCells
  57. Lo M-T, Novak V, Peng CK, Liu Y, Hu K. Assessment of nonlinear phase interaction between nonstationary signals: A comparison study of methods based on Hilbert-Huang and Fourier transforms. Phys Rev E. 2009; in press.
  58. Hu K, Van Someren E,JW Shea SA, Scheer FAJL. Reduction of scale-invariance of activity fluctuations with aging and Alzheimer's disease: involvement of the circadian pacemaker. Proc Natl Acad Sci. 2009; 106(8):2490-2494.
  59. Novak V, Haertle M, Zhao P, Hu K, Munshi M, Novak P, Abduljalil A, Alsop D. White matter hyperintensities and dynamics of postural control. Magn Reson Imaging. 2009 Jul; 27(6):752-9. PMID: 19250785.
    Citations: 14     Fields:    Translation:HumansCells
  60. Zhao P, Alsop DC, Abduljalil A, Selim M, Lipsitz L, Novak P, Caplan L, Hu K, Novak V. Vasoreactivity and peri-infarct hyperintensities in stroke. Neurology. 2009 Feb 17; 72(7):643-9. PMID: 19221298.
    Citations: 20     Fields:    Translation:Humans
  61. Hu K, Lo MT, Peng CK, Novak V, Schmidt EA, Kumar A, Czosnyka M. Nonlinear pressure-flow relationship is able to detect asymmetry of brain blood circulation associated with midline shift. J Neurotrauma. 2009 Feb 11; 26(2):227-33. PMID: 19196074.
    Citations: 10     Fields:    Translation:Humans
  62. Hu K, Van Someren EJ, Shea SA, Scheer FA. Reduction of scale invariance of activity fluctuations with aging and Alzheimer's disease: Involvement of the circadian pacemaker. Proc Natl Acad Sci U S A. 2009 Feb 24; 106(8):2490-4. PMID: 19202078.
    Citations: 54     Fields:    Translation:Humans
  63. Shea SA, Hu K, Scheer FA. Endogenous circadian rhythm of activity in humans. Sleep. 2008; 31:A46.
  64. Hu K, Van Someren E, Shea SA, Scheer FA. Reduction of scale-invariant activity control with aging and Alzheimer's disease: Possible involvement of the circadian pacemaker in multiscale regulation of human activity. Sleep. 2008; 31:A46-A47.
  65. Hu K, Scheer FA, Buijs RM, Shea SA. The circadian pacemaker generates similar circadian rhythms in the fractal structure of heart rate in humans and rats. Cardiovasc Res. 2008 Oct 01; 80(1):62-8. PMID: 18539630.
    Citations: 11     Fields:    Translation:HumansAnimals
  66. Scheer FA, Hu K, Evoniuk H, Kelly EE, Malhotra A, Doamekpor LA, Laker MD, Patel Y, Smales C, Shea SA . Additive influences of the endogenous circadian system and mental stress on cardiovascular risk factors. Sleep. 2008; 31:A51-A52.
  67. Hu K, Scheer FA, Evoniuk H, Kelly E, Laker M, Smales C, Shea SA. Influences of postural tilt stress and the circadian system on cardiovascular risk factors. Sleep. 2008; 31:A25.
  68. Scheer FA, Hu K, Evoniuk H, Kelly EE, Malhotra A, Hahn M, Laker MD, Patel Y, Smales C, Shea SA. Influence of endogenous circadian system, physical exercise, and their interaction on cardiovascular risk factors. Sleep. 2008; 31:A46.
  69. Hu K, Scheer FA, Buijs RM, Shea SA. The endogenous circadian pacemaker imparts a scale-invariant pattern of heart rate fluctuations across time scales spanning minutes to 24 hours. J Biol Rhythms. 2008 Jun; 23(3):265-73. PMID: 18487418.
    Citations: 13     Fields:    Translation:Animals
  70. Hu K, Peng CK, Huang NE, Wu Z, Lipsitz LA, Cavallerano J, Novak V. Altered Phase Interactions between Spontaneous Blood Pressure and Flow Fluctuations in Type 2 Diabetes Mellitus: Nonlinear Assessment of Cerebral Autoregulation. Physica A. 2008 Apr 01; 387(10):2279-2292. PMID: 18432311.
    Citations: 22     
  71. Hu K, Peng CK, Czosnyka M, Zhao P, Novak V. Nonlinear assessment of cerebral autoregulation from spontaneous blood pressure and cerebral blood flow fluctuations. Cardiovasc Eng. 2008 Mar; 8(1):60-71. PMID: 18080758.
    Citations: 28     Fields:    Translation:Humans
  72. Hu K, Scheer FAJL, Buijs RM, Shea SA. The Circadian Pacemaker Generates an Endogenous Circadian Rhythm in the Fractal Structure of Heart Rate in Nocturnal Rats. Cardiovascular Research. 2008; in press.
  73. Lo M-T, Hu K., Liu Y, Peng CK, Novak V. Multimodal Pressure Flow Analysis Enables Assessment of Cerebral Autoregulation Dynamics During Baseline Resting Conditions. Journal on Advances in Signal Processing. 2008; Accepted..
  74. Hu K, Peng CK, Huang NE, Wu Z, Lipsitz LA, Cavallerano J, Novak V. Altered Phase Interactions between Spontaneous Blood Pressure and Flow Fluctuations in Type 2 Diabetes Mellitus: Nonlinear Assessment of Cerebral Autoregulation. Physica A. 2008; 387(10):2279-2292.
  75. Lo MT, Hu K, Liu Y, Peng CK, Novak V. Multimodal Pressure Flow Analysis: Application of Hilbert Huang Transform in Cerebral Blood Flow Regulation. EURASIP J Adv Signal Process. 2008; 2008:785243. PMID: 18725996.
    Citations: 16     
  76. Ivanov PCh, Hu K, Hilton MF, Shea SA, Stanley HE. Endogenous circadian rhythms in human motor activity uncoupled from circadian influences on cardiac dynamics. Proc Natl Acad Sci. 2007; 104(52):20702-20707.
  77. Ivanov PCh, Hu K, Hilton MF, Shea SA, Stanley HE. Endogenous circadian rhythm in human motor activity uncoupled from circadian influences on cardiac dynamics. Proc Natl Acad Sci U S A. 2007 Dec 26; 104(52):20702-7. PMID: 18093917.
    Citations: 33     Fields:    Translation:Humans
  78. Hu K, Scheer FA, Ivanov PCh, Buijs RM, Shea SA. The suprachiasmatic nucleus functions beyond circadian rhythm generation. Neuroscience. 2007 Nov 09; 149(3):508-17. PMID: 17920204.
    Citations: 30     Fields:    Translation:HumansAnimals
  79. Last D, Alsop DC, Abduljalil AM, Marquis RP, de Bazelaire C, Hu K, Cavallerano J, Novak V. Global and regional effects of type 2 diabetes on brain tissue volumes and cerebral vasoreactivity. Diabetes Care. 2007 May; 30(5):1193-9. PMID: 17290035.
    Citations: 69     Fields:    Translation:Humans
  80. Selim MH, Jones RN, Hu K, Novak P, Novak V. Gender differences in cerebral hemodynamics in patients with diabetes, hypertension, and stroke: A transcranial Doppler ultrasound study. Stroke. 2007; 38:567.
  81. Hu K, Peng CK, Czosnyka M, Novak V . Assessment of impairment of dynamic cerebral autoregulation after traumatic brain injury using multimodal pressure flow analysis. Neurology. 2007; 68(12):A392 Suppl.1.
  82. Hu K, Scheer FAJL, Buijs RM, Shea SA. Effect of lesioning the suprachiasmatic nucleus on fractal pattern of heart rate fluctuations. SLEEP. 2007; 30:A64 186 Suppl. S.
  83. Hu K, Peng CK, Huang N, Wu Z, Lipsitz LA, Novak V. Assessment Of Impaired Cerebral Blood Flow Regulation in Type 2 Diabetes Mellitus Using Multimodal Pressure Flow Analysis. Diabetes. 2007; 56:A585 Suppl. 1.
  84. Shea SA, Hu K, Buijs RM, Scheer FAJL. Lesioning the suprachiasmatic nucleus abolishes ultradian rhythms of locomotor activity in rats. SLEEP. 2007; 30:A58 168 Suppl. S.
  85. Novak V, Hu K, Vyas M, Lipsitz LA. Cardio-Locomotor Coupling in Young and Old. Journals of Gerontology. 2007; 62:86-92..
  86. Hu K, Peng CK, Czosnyka M, Zhao P, Novak V. Nonlinear Assessment of Cerebral Autoregulation from Spontaneous Blood Pressure and Cerebral Perfusion Pressure Fluctuations. Cardiovascular Engineering. 2007; in Press..
  87. Hu K, Scheer FAJL, Buijs RM, Shea SA. The endogenous circadian pacemaker imparts a scale-invariant pattern of heart rate fluctuations across time scales spanning minutes to 24 hours. J Biol Rhythms. 2007; Accepted..
  88. Zhao P, Haertle M, Hu K, Larose S, Abdulajlil A, Alsop D, Novak V. Effects of white matter hyperintensities on balance in elderly with type 2 diabetes and hypertension. Diabetes. 2007; 56:A171 Suppl. 1.
  89. Novak V, Hu K, Vyas M, Lipsitz LA. Cardiolocomotor coupling in young and elderly people. J Gerontol A Biol Sci Med Sci. 2007 Jan; 62(1):86-92. PMID: 17301044.
    Citations: 8     Fields:    Translation:Humans
  90. Novak V, Last D, Alsop DC, Abduljalil AM, Hu K, Lepicovsky L, Cavallerano J, Lipsitz LA. Cerebral blood flow velocity and periventricular white matter hyperintensities in type 2 diabetes. Diabetes Care. 2006 Jul; 29(7):1529-34. PMID: 16801574.
    Citations: 55     Fields:    Translation:Humans
  91. Xu L, Chen Z, Hu K, Stanley HE, Ivanov PCh. Spurious detection of phase synchronization in coupled nonlinear oscillators. Phys Rev E Stat Nonlin Soft Matter Phys. 2006 Jun; 73(6 Pt 2):065201. PMID: 16906897.
    Citations: 14     Fields:    
  92. Chen Z, Hu K, Stanley HE, Novak V, Ivanov PCh. Cross-correlation of instantaneous phase increments in pressure-flow fluctuations: applications to cerebral autoregulation. Phys Rev E Stat Nonlin Soft Matter Phys. 2006 Mar; 73(3 Pt 1):031915. PMID: 16605566.
    Citations: 14     Fields:    Translation:HumansCTClinical Trials
  93. Novak V, Last D, Alsop DC, Abduljalil AM, Hu K, Lepicovaky L, Cavallerano J, Lipsitz LA. Cerebral Blood Flow and White Matter Hyperintensities in Type 2 Diabetes Mellitus. Diabetes Care. 2006; 29:1529-34..
  94. Chen Z, Hu K, Stanley HE, Novak V, Ivanov PCh. Cross-correlation of instantaneous phase increments in pressure-flow fluctuations: Applications to cerebral autoregulation. Phys Rev E. 2006; 73:031915..
  95. Hu K, Scheer FAJL, Ivanov PCh, Buijs RM, Shea SA. Intrinsic scale-invariant patterns of locomotor activity: Influence of the circadian pacemaker across a wide range of time scales - Spanning 4-24 hours. Sleep. 2006; 29:A64 190 Suppl. S.
  96. Hu K, Hilton MF, Ayers R, Ivanov PCh, Shea SA. An endogenous circadian rhythm in an index of cardiac vulnerability confirmed with a constant routine protocol. Sleep. 2006; 29:A68 202 Suppl. S.
  97. Hu K, Peng CK, Last D, Novak V. Age and gender effects on postural control dynamics assessed by stabilogram-diffusion analysis. Diabetes. 2006; 55:A579.
  98. Xu L, Chen Z, Hu K, Stanley HE, Ivanov PCh. Spurious detection of phase synchronization in coupled nonlinear oscillators. Phys Rev E. 2006; 74:065201..
  99. Robles CA, Hu K, Last D, Lepicovsky L, Novak P, Novak V. Effects of type 2 diabetes mellitus on foot pressure distribution during walking. Diabetes. 2006; 55:A543..
  100. Hessert MJ, Vyas M, Leach J, Hu K, Lipsitz LA, Novak V. Foot pressure distribution during walking in young and old adults. BMC Geriatr. 2005 May 19; 5:8. PMID: 15943881.
    Citations: 18     Fields:    Translation:Humans
  101. Xu L, Ivanov PCh, Hu K, Chen Z, Carbone A, Stanley HE. Quantifying signals with power-law correlations: a comparative study of detrended fluctuation analysis and detrended moving average techniques. Phys Rev E Stat Nonlin Soft Matter Phys. 2005 May; 71(5 Pt 1):051101. PMID: 16089515.
    Citations: 22     Fields:    
  102. Hu K, Ivanov PCh, Chen Z, Stanley HE, Hilton MF, Shea SA. Circadian rhythms and fractal fluctuations in forearm motion. APS March Meeting, March 24, 2005; Los Angeles, CA. APS March Meeting, Los Angeles, CA. 2005; V22.00008.
  103. Chen Z, Hu K, Carpena P, Bernaola-Galvan P, Stanley HE, Ivanov PCh. Effect of nonlinear filters on detrended fluctuation analysis. Phys Rev E Stat Nonlin Soft Matter Phys. 2005 Jan; 71(1 Pt 1):011104. PMID: 15697577.
    Citations: 15     Fields:    Translation:HumansAnimals
  104. Hu Kun. Statistical physics approaches to understanding physiological fluctuations. 2005.
  105. Xu L, Ivanov PCh, Hu K, Chen Z, Carbone A, Stanley HE. Quantifying signals with power-law correlations: A comparative study of detrended fluctuation analysis and detrended moving average techniques. Phys Rev E. 2005; 71:851101..
  106. Chen Z, Hu K, Carpena P, Bernaola-Galvan P, Stanley HE, Ivanov PCh. Effect of nonlinearity on detrended fluctuation analysis. Physical Review E. 2005; 71:011104.
  107. Hu K, Ivanov PCh, Hilton MF, Chen Z, Ayers RT, Stanley HE, Shea SA. Endogenous circadian rhythm in an index of cardiac vulnerability independent of changes in behavior. Proc Natl Acad Sci U S A. 2004 Dec 28; 101(52):18223-7. PMID: 15611476.
    Citations: 34     Fields:    Translation:Humans
  108. Angelini L, de Tommaso M, Guido M, Hu K, Ivanov PCh, Marinazzo D, Nardulli G, Nitti L, Pellicoro M, Pierro C, Stramaglia S. Steady-state visual evoked potentials and phase synchronization in migraine patients. Phys Rev Lett. 2004 Jul 16; 93(3):038103. PMID: 15323876.
    Citations: 16     Fields:    Translation:Humans
  109. Hu K, Ivanov PCh, Chen Z, Hilton MF, Stanley HE, Shea SA. Non-random fluctuations and multi-scale dynamics regulation of human activity. Physica A. 2004 Jun; 337(1-2):307-18. PMID: 15759365.
    Citations: 38     Translation:Humans
  110. Stramaglia S, Angelini L, Pellicoro M, Hu K, Ivanov PCh. EEG synchronization and migraine. APS March Meeting; Montreal, Quebec, Canada. 2004; W9.001.
  111. Ivanov PCh, Chen Z, Hu K, Stanley HE. Multiscale aspects of cardiac control. Physica A. 2004; 344:685-704..
  112. Hu K, Ivanov PCh, Hilton MF, Chen Z, Ayers RT, Stanley HE, Shea SA. Endogenous circadian rhythms in an index of cardiac vulnerability independent of changes in behavior. Proc Natl Acad Sci. 2004; 101:18223-7..
  113. Shi ZX, Wang HL, Hu K, Feng EL, Yao X, Su GF, Huang PT, Huang LY. Identification of alkA gene related to virulence of Shigella flexneri 2a by mutational analysis. World J Gastroenterol. 2003 Dec; 9(12):2720-5. PMID: 14669321.
    Citations: 3     Fields:    Translation:AnimalsCells
  114. Ivanov PCh, Hu K, Dammers J, Fieseler T, Tass PA. Detection of hierarchies and complex networks in cerebral synchronization patterns. APS March Meeting, Austin, TX. 2003; N15.012.
  115. Chen Z, Ivanov PCh, Hu K, Stanley HE, Novak V. Synchronization patterns in cerebral blood flow and peripheral blood pressure after a minor stroke. Noise in Complex Systems and Stochastic Dynamics. 2003; 5114:498-506.
  116. Hu K, Ivanov PCh, Chen Z, Hilton MF, Stanley HE, Shea SA. Novel multiscale regulation in human motor activity. Noise in Complex Systems and Stochastic Dynamics. 2003; 5110:235-43.
  117. Chen Z, Ivanov PCh, Hu K, Stanley HE. Effect of nonstationarities on detrended fluctuation analysis. Physical Review E. 2002; 65:041107..
  118. Hu K, Ivanov PCh, Chen Z, Carpena P, Stanley HE. Effect of trends on detrended fluctuation analysis. Physical Review E. 2001; 64:011114..
  119. Karbach M, Hu K, Muller G, Tobochnik J. Computer simulations ---Introduction to the Bethe ansatz II. Computers in Physics. 1998; 12(6):565-73..
  120. Xu XH, Fu RT, Hu K, Sun X, Yonemitsu K. Off-diagonal interactions and spin-density waves in polymers. Physical Review B. 1998; 58(14):9039-46..
  121. Sun X, Xu XH, Hu K, Yonemitsu K. Effect of electron correlation on competition between BOW and SDW in polymer. Physics Letters A. 1998; 239(3):191-5..
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.