Harvard Catalyst Profiles

Contact, publication, and social network information about Harvard faculty and fellows.

Kun Hu, Ph.D.

Profile Picture

Sun Yat-sen University , Guangzhou, PRCBS07/1995Material Science, Physics
University of Rhode Island, Kingston, RI, USAMS05/1999Quantum Physics
Boston University, Boston, MA, USAPhD02/2005Statistical Physics, Nonlinear Dynamics)
Beth Israel Deaconess Medical Center, Boston, MA, USAPostdoctoral11/2007Gerontology, Cardiovascular Physiology
Brigham & Women's Hospital, Boston, MA, USAPostdoctoral11/2007Circadian Physiology
B.S. Thesis award
Travel Award for Annual Meeting
Travel Award for Annual Meeting
Research Merit Trainee Travel Award
Travel Grant for Workshop "Short-term Cardiovascular-Respiratory Control Mechanisms"
Honorable Mention Abstract award
Investigator Award
Young Investigator
Chair's Research Award (Department of Medicine)
The Thousand Plan for Young Scholars (Selected but withdrawn)
Innovation Discovery Award

I obtained my doctoral training in statistical physics with a specific focus on nonlinear dynamic analysis and fractal physiology. During the first 5 years of my postdoctoral training, I have essentially involved in human experimental studies in two laboratories: Medical Chronobiology Program under the supervision of Dr. Steven Shea and Dr. Frank Scheer in the Division of Sleep and Circadian Disorders at BWH (sleep/circadian physiology); and SAFE (Syncope and Falls in the Elderly) Laboratory under the supervision of Dr. Vera Novak in the Division of Gerontology at Beth Israel Deaconess Medical Center (BIDMC) (for aging research). Between 2009-2011, I continued my advanced training in sleep/circadian physiology at BWH while learning about animal models involving neural lesions and gene knockouts in Dr. Clifford Saper’s lab in the Department of Neurology at BIDMC and in system biology under the guidance of Prof. Walter Fontana in the Department of System Biology at Harvard University.

With my multidisciplinary training, I have been promoting the application of the concepts/methods derived from statistical physics and nonlinear dynamics in medicine during the last 16 years. To foster such translational research in sleep medicine, I established Medical Biodynamics Program (MBP) in the Division of Sleep Medicine at HMS (https://sleep.hms.harvard.edu/research/labs-divisions/medical-biodynamics-program-mbp). My research over the last decade years has been continuously funded by the NIH (K99 HL102241, R00 HL102241, R01AG048108, RF1AG059867, RF1AG064312). The on-going projects in our group are aimed to understand the physiological impacts of Alzheimer's disease, and to develop cost-efficient, non-invasive biomarkers for predicting and monitoring the progression of the disease.

The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
  1. R01AG083799 (HU, KUN) Sep 15, 2023 - Jun 30, 2028
    Circadian disturbance and dementia in Latin America
    Role: Principal Investigator
  2. 290-FP-22 (Gao, Chenlu) Dec 16, 2022 - Dec 15, 2023
    American Academy of Sleep Medicine Foundation
    Daytime napping and Alzheimer's disease in middle-to-older aged adults: Timing, irregularity, and interaction with genetic risks
    Role Description: The goal of this project is to determine the changes of nap characteristics with age and the interaction effects of napping and genetics on cognitive decline and risk for Alzheimer’s dementia.
    Role: Co-mentor
  3. NA (Yuan, Robin) Dec 16, 2022 - Dec 15, 2023
    American Academy of Sleep Medicine Foundation
    Changes in heart rate variability in response to chronic circadian disruption with and without sleep restriction
    Role Description: The goal of this project is to examine the impact of chronic circadian disruption on autonomic control and sympathovagal balance
    Role: Mentor
  4. AARFD-22-928372 (Chenlu Gao) May 1, 2022 - Apr 30, 2023
    Alzheimer's Association
    Timing and irregularity of daytime napping and Alzheimer’s disease
    Role Description: The goal of this project is to determine the effects of timing and regularity of daytime napping on cognitive decline and the development/progression of Alzheimer’s disease
    Role: Co-mentor
  5. R33AG067069-01 HIV/Aging Pilot Award (Peng Li) Apr 21, 2021 - Mar 31, 2022
    Association between rest activity rhythm and cognition in PLWH
    Role Description: The goal of this pilot study is to examine alterations in the rest-activity circadian rhythm in people living with HIV infection using nonlinear rhythmicity analysis, determine the links between the rhythm to cognition, and explore the potential mechanisms underlying their association in terms of multimorbidity
    Role: Other Significant Contributor

Featured Content

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
Newest   |   Oldest   |   Most Cited   |   Most Discussed   |   Timeline   |   Field Summary   |   Plain Text
PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
This operation might take several minutes to complete. Please do not close your browser.
Local representatives can answer questions about the Profiles website or help with editing a profile or issues with profile data. For assistance with this profile: HMS/HSDM faculty should contact contactcatalyst.harvard.edu. For faculty or fellow appointment updates and changes, please ask your appointing department to contact HMS. For fellow personal and demographic information, contact HMS Human Resources at human_resourceshms.harvard.edu. For faculty personal and demographic information, contact HMS Office for Faculty Affairs at facappthms.harvard.edu.
Hu's Networks
Click the
buttons for more information and interactive visualizations!
Concepts (269)
Co-Authors (33)
Similar People (60)
Same Department 
Physical Neighbors
Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.