Harvard Catalyst Profiles

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George Sorescu, B.S.

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Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Hawkins F, Ebel N, Sorescu GP, McMahon L, Sprinz P, Klings ES. Keeping it in the family: three relatives with HbSC disease and simultaneous acute pulmonary emboli. Am J Hematol. 2012 Jan; 87(1):101-4. PMID: 21953788.
    Citations:    Fields:    Translation:Humans
  2. Arita T, Sorescu GP, Schuler BT, Schmarkey LS, Merlino JD, Vinten-Johansen J, Leon AR, Martin RP, Sorescu D. Speckle-tracking strain echocardiography for detecting cardiac dyssynchrony in a canine model of dyssynchrony and heart failure. . 2007 Jul; 293(1):H735-42. PMID: 17449554.
    Citations: 8     Translation:HumansAnimals
  3. Clempus RE, Sorescu D, Dikalova AE, Pounkova L, Jo P, Sorescu GP, Schmidt HH, Lassègue B, Griendling KK. Nox4 is required for maintenance of the differentiated vascular smooth muscle cell phenotype. Arterioscler Thromb Vasc Biol. 2007 Jan; 27(1):42-8. PMID: 17082491.
    Citations: 139     Fields:    Translation:AnimalsCells
  4. Butcher JT, Tressel S, Johnson T, Turner D, Sorescu G, Jo H, Nerem RM. Transcriptional profiles of valvular and vascular endothelial cells reveal phenotypic differences: influence of shear stress. Arterioscler Thromb Vasc Biol. 2006 Jan; 26(1):69-77. PMID: 16293796.
    Citations: 58     Fields:    Translation:AnimalsCells
  5. Pardo SJ, Patel MJ, Sykes MC, Platt MO, Boyd NL, Sorescu GP, Xu M, van Loon JJ, Wang MD, Jo H. Simulated microgravity using the Random Positioning Machine inhibits differentiation and alters gene expression profiles of 2T3 preosteoblasts. . 2005 Jun; 288(6):C1211-21. PMID: 15689415.
    Citations: 38     Translation:AnimalsCells
  6. Sorescu GP, Song H, Tressel SL, Hwang J, Dikalov S, Smith DA, Boyd NL, Platt MO, Lassègue B, Griendling KK, Jo H. Bone morphogenic protein 4 produced in endothelial cells by oscillatory shear stress induces monocyte adhesion by stimulating reactive oxygen species production from a nox1-based NADPH oxidase. Circ Res. 2004 Oct 15; 95(8):773-9. PMID: 15388638.
    Citations: 142     Fields:    Translation:HumansAnimalsCells
  7. Mohan S, Hamuro M, Koyoma K, Sorescu GP, Jo H, Natarajan M. High glucose induced NF-kappaB DNA-binding activity in HAEC is maintained under low shear stress but inhibited under high shear stress: role of nitric oxide. Atherosclerosis. 2003 Dec; 171(2):225-34. PMID: 14644391.
    Citations: 6     Fields:    Translation:HumansAnimalsCells
  8. Boo YC, Sorescu GP, Bauer PM, Fulton D, Kemp BE, Harrison DG, Sessa WC, Jo H. Endothelial NO synthase phosphorylated at SER635 produces NO without requiring intracellular calcium increase. Free Radic Biol Med. 2003 Oct 01; 35(7):729-41. PMID: 14583337.
    Citations: 30     Fields:    Translation:HumansAnimalsCells
  9. Hwang J, Saha A, Boo YC, Sorescu GP, McNally JS, Holland SM, Dikalov S, Giddens DP, Griendling KK, Harrison DG, Jo H. Oscillatory shear stress stimulates endothelial production of O2- from p47phox-dependent NAD(P)H oxidases, leading to monocyte adhesion. J Biol Chem. 2003 Nov 21; 278(47):47291-8. PMID: 12958309.
    Citations: 107     Fields:    Translation:AnimalsCells
  10. Sorescu GP, Sykes M, Weiss D, Platt MO, Saha A, Hwang J, Boyd N, Boo YC, Vega JD, Taylor WR, Jo H. Bone morphogenic protein 4 produced in endothelial cells by oscillatory shear stress stimulates an inflammatory response. J Biol Chem. 2003 Aug 15; 278(33):31128-35. PMID: 12766166.
    Citations: 96     Fields:    Translation:HumansAnimalsCells
  11. Boyd NL, Park H, Yi H, Boo YC, Sorescu GP, Sykes M, Jo H. Chronic shear induces caveolae formation and alters ERK and Akt responses in endothelial cells. . 2003 Sep; 285(3):H1113-22. PMID: 12763750.
    Citations: 52     Translation:AnimalsCells
  12. Mohan S, Hamuro M, Sorescu GP, Koyoma K, Sprague EA, Jo H, Valente AJ, Prihoda TJ, Natarajan M. IkappaBalpha-dependent regulation of low-shear flow-induced NF-kappa B activity: role of nitric oxide. . 2003 Apr; 284(4):C1039-47. PMID: 12620896.
    Citations: 7     Translation:HumansCells
  13. Xiao K, Allison DF, Kottke MD, Summers S, Sorescu GP, Faundez V, Kowalczyk AP. Mechanisms of VE-cadherin processing and degradation in microvascular endothelial cells. J Biol Chem. 2003 May 23; 278(21):19199-208. PMID: 12626512.
    Citations: 67     Fields:    Translation:HumansAnimalsCells
  14. Bauer PM, Fulton D, Boo YC, Sorescu GP, Kemp BE, Jo H, Sessa WC. Compensatory phosphorylation and protein-protein interactions revealed by loss of function and gain of function mutants of multiple serine phosphorylation sites in endothelial nitric-oxide synthase. J Biol Chem. 2003 Apr 25; 278(17):14841-9. PMID: 12591925.
    Citations: 79     Fields:    Translation:AnimalsCells
  15. Sorescu D, Weiss D, Lassègue B, Clempus RE, Szöcs K, Sorescu GP, Valppu L, Quinn MT, Lambeth JD, Vega JD, Taylor WR, Griendling KK. Superoxide production and expression of nox family proteins in human atherosclerosis. Circulation. 2002 Mar 26; 105(12):1429-35. PMID: 11914250.
    Citations: 238     Fields:    Translation:HumansCells
  16. Boo YC, Sorescu G, Boyd N, Shiojima I, Walsh K, Du J, Jo H. Shear stress stimulates phosphorylation of endothelial nitric-oxide synthase at Ser1179 by Akt-independent mechanisms: role of protein kinase A. J Biol Chem. 2002 Feb 01; 277(5):3388-96. PMID: 11729190.
    Citations: 129     Fields:    Translation:AnimalsCells
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.