Harvard Catalyst Profiles

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Ian Roundtree, M.D., Ph.D.


Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Fei Q, Zou Z, Roundtree IA, Sun HL, He C. YTHDF2 promotes mitotic entry and is regulated by cell cycle mediators. PLoS Biol. 2020 04; 18(4):e3000664. PMID: 32267835.
    Citations: 17     Fields:    Translation:HumansCells
  2. Zhang Z, Chen LQ, Zhao YL, Yang CG, Roundtree IA, Zhang Z, Ren J, Xie W, He C, Luo GZ. Single-base mapping of m6A by an antibody-independent method. Sci Adv. 2019 07; 5(7):eaax0250. PMID: 31281898.
    Citations: 76     Fields:    Translation:HumansAnimals
  3. Zhao BS, Roundtree IA, He C. Publisher Correction: Post-transcriptional gene regulation by mRNA modifications. Nat Rev Mol Cell Biol. 2018 Dec; 19(12):808. PMID: 30341428.
    Citations: 9     Fields:    
  4. Zhao BS, Nachtergaele S, Roundtree IA, He C. Our views of dynamic N6-methyladenosine RNA methylation. RNA. 2018 03; 24(3):268-272. PMID: 29222116.
    Citations: 26     Fields:    Translation:Cells
  5. Roundtree IA, Luo GZ, Zhang Z, Wang X, Zhou T, Cui Y, Sha J, Huang X, Guerrero L, Xie P, He E, Shen B, He C. YTHDC1 mediates nuclear export of N6-methyladenosine methylated mRNAs. Elife. 2017 10 06; 6. PMID: 28984244.
    Citations: 339     Fields:    Translation:HumansCells
  6. Roundtree IA, Evans ME, Pan T, He C. Dynamic RNA Modifications in Gene Expression Regulation. Cell. 2017 Jun 15; 169(7):1187-1200. PMID: 28622506.
    Citations: 858     Fields:    Translation:HumansAnimalsCells
  7. Zhao BS, Roundtree IA, He C. Post-transcriptional gene regulation by mRNA modifications. Nat Rev Mol Cell Biol. 2017 01; 18(1):31-42. PMID: 27808276.
    Citations: 658     Fields:    Translation:HumansAnimalsCells
  8. Roundtree IA, He C. Nuclear m(6)A Reader YTHDC1 Regulates mRNA Splicing. Trends Genet. 2016 06; 32(6):320-321. PMID: 27050931.
    Citations: 51     Fields:    Translation:AnimalsCells
  9. Roundtree IA, He C. RNA epigenetics--chemical messages for posttranscriptional gene regulation. Curr Opin Chem Biol. 2016 Feb; 30:46-51. PMID: 26625014.
    Citations: 57     Fields:    Translation:HumansAnimalsCells
  10. Xu C, Wang X, Liu K, Roundtree IA, Tempel W, Li Y, Lu Z, He C, Min J. Corrigendum: Structural basis for selective binding of m(6)A RNA by the YTHDC1 YTH domain. Nat Chem Biol. 2015 Oct; 11(10):815. PMID: 26379027.
    Citations: 3     Fields:    
  11. Wang X, Zhao BS, Roundtree IA, Lu Z, Han D, Ma H, Weng X, Chen K, Shi H, He C. N(6)-methyladenosine Modulates Messenger RNA Translation Efficiency. Cell. 2015 Jun 04; 161(6):1388-99. PMID: 26046440.
    Citations: 1079     Fields:    Translation:HumansCells
  12. Zhu T, Roundtree IA, Wang P, Wang X, Wang L, Sun C, Tian Y, Li J, He C, Xu Y. Crystal structure of the YTH domain of YTHDF2 reveals mechanism for recognition of N6-methyladenosine. Cell Res. 2014 Dec; 24(12):1493-6. PMID: 25412661.
    Citations: 130     Fields:    Translation:HumansCells
  13. Xu C, Wang X, Liu K, Roundtree IA, Tempel W, Li Y, Lu Z, He C, Min J. Structural basis for selective binding of m6A RNA by the YTHDC1 YTH domain. Nat Chem Biol. 2014 Nov; 10(11):927-9. PMID: 25242552.
    Citations: 272     Fields:    Translation:HumansCells
  14. Ferris GE, Hong K, Roundtree IA, Morken JP. A catalytic enantioselective tandem allylation strategy for rapid terpene construction: application to the synthesis of pumilaside aglycon. J Am Chem Soc. 2013 Feb 20; 135(7):2501-4. PMID: 23390951.
    Citations: 10     Fields:    Translation:Cells
  15. Zhang P, Roundtree IA, Morken JP. Ni- and Pd-catalyzed synthesis of substituted and functionalized allylic boronates. Org Lett. 2012 Mar 16; 14(6):1416-9. PMID: 22375950.
    Citations: 10     Fields:    Translation:Cells
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.