Harvard Catalyst Profiles

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Natasha Y. Frank, M.D.

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Research
The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
  1. R24EY028767 (FRANK, NATASHA Y) Apr 1, 2018 - Jan 31, 2023
    NIH
    Multipotent ABCB5-positive cell therapeutics for corneal disease
    Role: Principal Investigator
  2. R01EY025794 (FRANK, MARKUS H.) Apr 1, 2016 - Mar 31, 2021
    NIH
    ABCB5-positive stem cells for LSCD therapy
    Role: Principal Investigator
  3. I01RX000989 (FRANK, NATASHA Y) Jul 1, 2013 - Jun 30, 2019
    NIH
    ABCB5+ Dermal Stem Cells In Regenerative Wound Healing
    Role: Principal Investigator
  4. I01BX000516 (FRANK, NATASHA Y) Oct 1, 2009 - Jun 30, 2021
    NIH
    Identification and targeting of colon cancer initiating cells
    Role: Principal Investigator
  5. K08NS051349 (FRANK, NATASHA Y) Jan 1, 2006 - Dec 31, 2011
    NIH
    Myoregenerative Potential of ABCB5+ Progenitors
    Role: Principal Investigator

Bibliographic
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Domdey M, Kluth MA, Maßlo C, Ganss C, Frank MH, Frank NY, Coroneo MT, Cursiefen C, Notara M. Consecutive dosing of UVB irradiation induces loss of ABCB5 expression and activation of EMT and fibrosis proteins in limbal epithelial cells similar to pterygium epithelium. Stem Cell Res. 2022 10; 64:102936. PMID: 36242878; PMCID: PMC9582195.
    Citations:    Fields:    
  2. Kerstan A, Dieter K, Niebergall-Roth E, Klingele S, Jünger M, Hasslacher C, Daeschlein G, Stemler L, Meyer-Pannwitt U, Schubert K, Klausmann G, Raab T, Goebeler M, Kraft K, Esterlechner J, Schröder HM, Sadeghi S, Ballikaya S, Gasser M, Waaga-Gasser AM, Murphy GF, Orgill DP, Frank NY, Ganss C, Scharffetter-Kochanek K, Frank MH, Kluth MA. Translational development of ABCB5+ dermal mesenchymal stem cells for therapeutic induction of angiogenesis in non-healing diabetic foot ulcers. Stem Cell Res Ther. 2022 09 05; 13(1):455. PMID: 36064604; PMCID: PMC9444095.
    Citations:    Fields:    
  3. Sasamoto Y, Lee CAA, Wilson BJ, Buerger F, Martin G, Mishra A, Kiritoshi S, Tran J, Gonzalez G, Hildebrandt F, Jo VY, Lian CG, Murphy GF, Ksander BR, Frank MH, Frank NY. Limbal BCAM expression identifies a proliferative progenitor population capable of holoclone formation and corneal differentiation. Cell Rep. 2022 08 09; 40(6):111166. PMID: 35947947; PMCID: PMC9480518.
    Citations:    Fields:    
  4. Kiritsi D, Dieter K, Niebergall-Roth E, Fluhr S, Daniele C, Esterlechner J, Sadeghi S, Ballikaya S, Erdinger L, Schauer F, Gewert S, Laimer M, Bauer JW, Hovnanian A, Zambruno G, El Hachem M, Bourrat E, Papanikolaou M, Petrof G, Kitzmüller S, Ebens CL, Frank MH, Frank NY, Ganss C, Martinez AE, McGrath JA, Tolar J, Kluth MA. Clinical trial of ABCB5+ mesenchymal stem cells for recessive dystrophic epidermolysis bullosa. JCI Insight. 2021 11 22; 6(22). PMID: 34665781; PMCID: PMC8663784.
    Citations: 2     Fields:    Translation:HumansAnimalsCells
  5. Singh K, Maity P, Koroma AK, Basu A, Pandey RK, Vander Beken S, Haas P, Krug L, Hainzl A, Sindrilaru A, Pfeiffer C, Wlaschek M, Frank NY, Frank MH, Ganss C, Bánvölgyi A, Wikonkál N, Eming S, Pastar I, Tomic-Canic M, Kluth MA, Scharffetter-Kochanek K. Angiogenin Released from ABCB5+ Stromal Precursors Improves Healing of Diabetic Wounds by Promoting Angiogenesis. J Invest Dermatol. 2022 06; 142(6):1725-1736.e10. PMID: 34808236.
    Citations: 3     Fields:    Translation:Animals
  6. Kerstan A, Dieter K, Niebergall-Roth E, Dachtler AK, Kraft K, Stücker M, Daeschlein G, Jünger M, Görge T, Meyer-Pannwitt U, Erfurt-Berge C, von Engelhardt C, Klare A, Pfeiffer C, Esterlechner J, Schröder HM, Gasser M, Waaga-Gasser AM, Goebeler M, Ballikaya S, Sadeghi S, Murphy GF, Orgill DP, Frank NY, Ganss C, Scharffetter-Kochanek K, Frank MH, Kluth MA. Allogeneic ABCB5+ mesenchymal stem cells for treatment-refractory chronic venous ulcers: a phase I/IIa clinical trial. JID Innov. 2022 Jan; 2(1). PMID: 34870260.
    Citations: 3     
  7. Sasamoto Y, Lee CAA, Yoshihara M, Martin G, Ksander BR, Frank MH, Frank NY. High expression of SARS-CoV2 viral entry-related proteins in human limbal stem cells. Ocul Surf. 2022 01; 23:197-200. PMID: 34653711; PMCID: PMC8511872.
    Citations: 4     Fields:    Translation:HumansCells
  8. Watanabe S, Hayashi R, Sasamoto Y, Tsujikawa M, Ksander BR, Frank MH, Quantock AJ, Frank NY, Nishida K. Human iPS cells engender corneal epithelial stem cells with holoclone-forming capabilities. iScience. 2021 Jun 25; 24(6):102688. PMID: 34195566.
    Citations: 2     
  9. Norrick A, Esterlechner J, Niebergall-Roth E, Dehio U, Sadeghi S, Schröder HM, Ballikaya S, Stemler N, Ganss C, Dieter K, Dachtler AK, Merz P, Sel S, Chodosh J, Cursiefen C, Frank NY, Auffarth GU, Ksander B, Frank MH, Kluth MA. Process development and safety evaluation of ABCB5+ limbal stem cells as advanced-therapy medicinal product to treat limbal stem cell deficiency. Stem Cell Res Ther. 2021 03 19; 12(1):194. PMID: 33741066; PMCID: PMC7980611.
    Citations: 7     Fields:    Translation:HumansAnimalsCells
  10. Riedl J, Pickett-Leonard M, Eide C, Kluth MA, Ganss C, Frank NY, Frank MH, Ebens CL, Tolar J. ABCB5+ dermal mesenchymal stromal cells with favorable skin homing and local immunomodulation for recessive dystrophic epidermolysis bullosa treatment. Stem Cells. 2021 07; 39(7):897-903. PMID: 33609408; PMCID: PMC8278965.
    Citations: 7     Fields:    Translation:AnimalsCells
  11. Frank MH, Wilson BJ, Gold JS, Frank NY. Clinical Implications of Colorectal Cancer Stem Cells in the Age of Single-Cell Omics and Targeted Therapies. Gastroenterology. 2021 05; 160(6):1947-1960. PMID: 33617889; PMCID: PMC8215897.
    Citations: 9     Fields:    Translation:HumansAnimalsCells
  12. Zu T, Wang D, Xu S, Lee CAA, Zhen E, Yoon CH, Abarzua P, Wang S, Frank NY, Wu X, Lian CG, Murphy GF. ATF-3 expression inhibits melanoma growth by downregulating ERK and AKT pathways. Lab Invest. 2021 05; 101(5):636-647. PMID: 33299127; PMCID: PMC8091967.
    Citations: 2     Fields:    Translation:HumansAnimalsCells
  13. Kerstan A, Niebergall-Roth E, Esterlechner J, Schröder HM, Gasser M, Waaga-Gasser AM, Goebeler M, Rak K, Schrüfer P, Endres S, Hagenbusch P, Kraft K, Dieter K, Ballikaya S, Stemler N, Sadeghi S, Tappenbeck N, Murphy GF, Orgill DP, Frank NY, Ganss C, Scharffetter-Kochanek K, Frank MH, Kluth MA. Ex vivo-expanded highly pure ABCB5+ mesenchymal stromal cells as Good Manufacturing Practice-compliant autologous advanced therapy medicinal product for clinical use: process validation and first in-human data. Cytotherapy. 2021 02; 23(2):165-175. PMID: 33011075.
    Citations: 11     Fields:    Translation:HumansCells
  14. Lee CAA, Banerjee P, Wilson BJ, Wu S, Guo Q, Berg G, Karpova S, Mishra A, Lian JW, Tran J, Emmerich M, Murphy GF, Frank MH, Frank NY. Targeting the ABC transporter ABCB5 sensitizes glioblastoma to temozolomide-induced apoptosis through a cell-cycle checkpoint regulation mechanism. J Biol Chem. 2020 05 29; 295(22):7774-7788. PMID: 32317280.
    Citations: 9     Fields:    Translation:HumansAnimalsCells
  15. Li F, Yuan CW, Xu S, Zu T, Woappi Y, Lee CAA, Abarzua P, Wells M, Ramsey MR, Frank NY, Wu X, Mandinova A, Frank MH, Lian CG, Murphy GF. Loss of the Epigenetic Mark 5-hmC in Psoriasis: Implications for Epidermal Stem Cell Dysregulation. J Invest Dermatol. 2020 06; 140(6):1266-1275.e3. PMID: 31837302; PMCID: PMC7931370.
    Citations: 7     Fields:    Translation:HumansAnimalsCells
  16. Sasamoto Y, Sasamoto N, Tran J, Mishra A, Ksander BR, Frank MH, Frank NY. Investigation of factors associated with ABCB5-positive limbal stem cell isolation yields from human donors. Ocul Surf. 2020 01; 18(1):114-120. PMID: 31655212.
    Citations: 4     Fields:    Translation:HumansCells
  17. Vander Beken S, de Vries JC, Meier-Schiesser B, Meyer P, Jiang D, Sindrilaru A, Ferreira FF, Hainzl A, Schatz S, Muschhammer J, Scheurmann NJ, Kampilafkos P, Seitz AM, Dürselen L, Ignatius A, Kluth MA, Ganss C, Wlaschek M, Singh K, Maity P, Frank NY, Frank MH, Scharffetter-Kochanek K. Newly Defined ATP-Binding Cassette Subfamily B Member 5 Positive Dermal Mesenchymal Stem Cells Promote Healing of Chronic Iron-Overload Wounds via Secretion of Interleukin-1 Receptor Antagonist. Stem Cells. 2019 08; 37(8):1057-1074. PMID: 31002437.
    Citations: 18     Fields:    Translation:HumansAnimalsCells
  18. Tappenbeck N, Schröder HM, Niebergall-Roth E, Hassinger F, Dehio U, Dieter K, Kraft K, Kerstan A, Esterlechner J, Frank NY, Scharffetter-Kochanek K, Murphy GF, Orgill DP, Beck J, Frank MH, Ganss C, Kluth MA. In vivo safety profile and biodistribution of GMP-manufactured human skin-derived ABCB5-positive mesenchymal stromal cells for use in clinical trials. Cytotherapy. 2019 05; 21(5):546-560. PMID: 30878384; PMCID: PMC6513723.
    Citations: 24     Fields:    Translation:HumansAnimalsCells
  19. Velilla J, Marchetti MM, Toth-Petroczy A, Grosgogeat C, Bennett AH, Carmichael N, Estrella E, Darras BT, Frank NY, Krier J, Gaudet R, Gupta VA. Homozygous TRPV4 mutation causes congenital distal spinal muscular atrophy and arthrogryposis. Neurol Genet. 2019 Apr; 5(2):e312. PMID: 31041394; PMCID: PMC6454305.
    Citations: 7     
  20. Haghighi A, Krier JB, Toth-Petroczy A, Cassa CA, Frank NY, Carmichael N, Fieg E, Bjonnes A, Mohanty A, Briere LC, Lincoln S, Lucia S, Gupta VA, Söylemez O, Sutti S, Kooshesh K, Qiu H, Fay CJ, Perroni V, Valerius J, Hanna M, Frank A, Ouahed J, Snapper SB, Pantazi A, Chopra SS, Leshchiner I, Stitziel NO, Feldweg A, Mannstadt M, Loscalzo J, Sweetser DA, Liao E, Stoler JM, Nowak CB, Sanchez-Lara PA, Klein OD, Perry H, Patsopoulos NA, Raychaudhuri S, Goessling W, Green RC, Seidman CE, MacRae CA, Sunyaev SR, Maas RL, Vuzman D. An integrated clinical program and crowdsourcing strategy for genomic sequencing and Mendelian disease gene discovery. NPJ Genom Med. 2018; 3:21. PMID: 30131872; PMCID: PMC6089983.
    Citations: 7     
  21. Guo Q, Grimmig T, Gonzalez G, Giobbie-Hurder A, Berg G, Carr N, Wilson BJ, Banerjee P, Ma J, Gold JS, Nandi B, Huang Q, Waaga-Gasser AM, Lian CG, Murphy GF, Frank MH, Gasser M, Frank NY. ATP-binding cassette member B5 (ABCB5) promotes tumor cell invasiveness in human colorectal cancer. J Biol Chem. 2018 07 13; 293(28):11166-11178. PMID: 29789423; PMCID: PMC6052213.
    Citations: 18     Fields:    Translation:HumansAnimalsCells
  22. Sasamoto Y, Ksander BR, Frank MH, Frank NY. Repairing the corneal epithelium using limbal stem cells or alternative cell-based therapies. Expert Opin Biol Ther. 2018 05; 18(5):505-513. PMID: 29471701; PMCID: PMC6317528.
    Citations: 16     Fields:    Translation:HumansCells
  23. Gonzalez G, Sasamoto Y, Ksander BR, Frank MH, Frank NY. Limbal stem cells: identity, developmental origin, and therapeutic potential. Wiley Interdiscip Rev Dev Biol. 2018 03; 7(2). PMID: 29105366.
    Citations: 35     Fields:    Translation:HumansAnimalsCells
  24. Webber BR, O'Connor KT, McElmurry RT, Durgin EN, Eide CR, Lees CJ, Riddle MJ, Mathews WE, Frank NY, Kluth MA, Ganss C, Moriarity BS, Frank MH, Osborn MJ, Tolar J. Rapid generation of Col7a1-/- mouse model of recessive dystrophic epidermolysis bullosa and partial rescue via immunosuppressive dermal mesenchymal stem cells. Lab Invest. 2017 10; 97(10):1218-1224. PMID: 28892093; PMCID: PMC5623156.
    Citations: 13     Fields:    Translation:AnimalsCells
  25. Joseph K, Constantino-Silva RN, Grumach AS, Feldweg A, Wright L, Frank N, Vuzman D, Sharma R, Suffritti C, Cicardi M, Varga L, Farkas H, Bork K, Kaplan AP. Reply. J Allergy Clin Immunol. 2017 05; 139(5):1720-1721. PMID: 28318557.
    Citations:    Fields:    Translation:Humans
  26. O'Donnell-Luria AH, Lin AP, Merugumala SK, Rohr F, Waisbren SE, Lynch R, Tchekmedyian V, Goldberg AD, Bellinger A, McFaline-Figueroa JR, Simon T, Gershanik EF, Levy BD, Cohen DE, Samuels MA, Berry GT, Frank NY. Brain MRS glutamine as a biomarker to guide therapy of hyperammonemic coma. Mol Genet Metab. 2017 05; 121(1):9-15. PMID: 28408159.
    Citations: 4     Fields:    Translation:Humans
  27. Hermanns C, Hampl V, Holzer K, Aigner A, Penkava J, Frank N, Martin DE, Maier KC, Waldburger N, Roessler S, Goppelt-Struebe M, Akrap I, Thavamani A, Singer S, Nordheim A, Gudermann T, Muehlich S. The novel MKL target gene myoferlin modulates expansion and senescence of hepatocellular carcinoma. Oncogene. 2017 06 15; 36(24):3464-3476. PMID: 28114277.
    Citations: 20     Fields:    Translation:HumansAnimalsCells
  28. Gasser M, Kim M, Rehder R, Frank N, Frank M, Grimmig T, Moench R, Ribas C, Illert B, Germer CT, Rosenwald A, Waaga-Gasser AM. Clinical Significance of Disseminated Pluripotent Tumor Cell Signature Expression in the Bone Marrow from Patients with Colorectal Cancer. J Cancer Sci Ther. 2017; 9(10):669-674. PMID: 34221246; PMCID: PMC8248589.
    Citations:    
  29. Shapiro M, Nandi B, Gonzalez G, Prabhala RH, Mashimo H, Huang Q, Frank NY, Munshi NC, Gold JS. Deficiency of the immunostimulatory cytokine IL-21 promotes intestinal neoplasia via dysregulation of the Th1/Th17 axis. Oncoimmunology. 2017; 6(1):e1261776. PMID: 28197386.
    Citations: 5     Fields:    
  30. Casey J, Vaidya A, Frank NY, Beckman JA, Miller A. Dissecting a Case of Abdominal Pain. N Engl J Med. 2016 10 27; 375(17):e35. PMID: 27783920.
    Citations:    Fields:    Translation:Humans
  31. Siemeni T, Knöfel AK, Madrahimov N, Sommer W, Avsar M, Salman J, Ius F, Frank N, Büchler G, Jonigk D, Jansson K, Maus U, Tudorache I, Falk CS, Haverich A, Warnecke G. In Vivo Development of Transplant Arteriosclerosis in Humanized Mice Reflects Alloantigen Recognition and Peripheral Treg Phenotype of Lung Transplant Recipients. Am J Transplant. 2016 11; 16(11):3150-3162. PMID: 27273729.
    Citations: 4     Fields:    Translation:HumansAnimalsCells
  32. Lee VS, Halabi CM, Hoffman EP, Carmichael N, Leshchiner I, Lian CG, Bierhals AJ, Vuzman D, Mecham RP, Frank NY, Stitziel NO. Loss of function mutation in LOX causes thoracic aortic aneurysm and dissection in humans. Proc Natl Acad Sci U S A. 2016 08 02; 113(31):8759-64. PMID: 27432961; PMCID: PMC4978273.
    Citations: 70     Fields:    Translation:HumansAnimalsCells
  33. Jiang D, Muschhammer J, Qi Y, Kügler A, de Vries JC, Saffarzadeh M, Sindrilaru A, Beken SV, Wlaschek M, Kluth MA, Ganss C, Frank NY, Frank MH, Preissner KT, Scharffetter-Kochanek K. Suppression of Neutrophil-Mediated Tissue Damage-A Novel Skill of Mesenchymal Stem Cells. Stem Cells. 2016 09; 34(9):2393-406. PMID: 27299700.
    Citations: 66     Fields:    Translation:HumansAnimalsCells
  34. Nandi B, Shapiro M, Samur MK, Pai C, Frank NY, Yoon C, Prabhala RH, Munshi NC, Gold JS. Stromal CCR6 drives tumor growth in a murine transplantable colon cancer through recruitment of tumor-promoting macrophages. Oncoimmunology. 2016 Aug; 5(8):e1189052. PMID: 27622061.
    Citations: 33     Fields:    
  35. Cassa CA, Smith SE, Docken W, Hoffman E, McLaughlin H, Chun S, Leshchiner I, Miraoui H, Raychaudhuri S, Frank NY, Wilson BJ, Sunyaev SR, Maas RL, Vuzman D. An argument for early genomic sequencing in atypical cases: a WISP3 variant leads to diagnosis of progressive pseudorheumatoid arthropathy of childhood. Rheumatology (Oxford). 2016 Mar; 55(3):586-9. PMID: 26493744; PMCID: PMC5009447.
    Citations: 4     Fields:    Translation:Humans
  36. Schatton T, Yang J, Kleffel S, Uehara M, Barthel SR, Schlapbach C, Zhan Q, Dudeney S, Mueller H, Lee N, de Vries JC, Meier B, Vander Beken S, Kluth MA, Ganss C, Sharpe AH, Waaga-Gasser AM, Sayegh MH, Abdi R, Scharffetter-Kochanek K, Murphy GF, Kupper TS, Frank NY, Frank MH. ABCB5 Identifies Immunoregulatory Dermal Cells. Cell Rep. 2015 Sep 08; 12(10):1564-74. PMID: 26321644.
    Citations: 29     Fields:    Translation:HumansAnimalsCells
  37. Sheu J, Divito SJ, Hoffman EP, Frank NY, Merola JF. Mosaic focal dermal hypoplasia caused by a novel somatic mutation in PORCN detected in affected skin. Br J Dermatol. 2015 Aug; 173(2):568-70. PMID: 25640089.
    Citations: 3     Fields:    Translation:Humans
  38. de Waard NE, Kolovou PE, McGuire SP, Cao J, Frank NY, Frank MH, Jager MJ, Ksander BR. Expression of Multidrug Resistance Transporter ABCB5 in a Murine Model of Human Conjunctival Melanoma. Ocul Oncol Pathol. 2015 Apr; 1(3):182-189. PMID: 25960995; PMCID: PMC4423550.
    Citations: 5     
  39. Frank MH, Frank NY. Restoring the cornea from limbal stem cells. Regen Med. 2015; 10(1):1-4. PMID: 25562345; PMCID: PMC4293634.
    Citations: 10     Fields:    Translation:HumansCells
  40. Böhm E, Lippold J, Gutjahr M, Frank M, Blaser P, Antz B, Fohlmeister J, Frank N, Andersen MB, Deininger M. Strong and deep Atlantic meridional overturning circulation during the last glacial cycle. Nature. 2015 Jan 01; 517(7532):73-6. PMID: 25517093.
    Citations: 29     Fields:    Translation:Animals
  41. Ksander BR, Kolovou PE, Wilson BJ, Saab KR, Guo Q, Ma J, McGuire SP, Gregory MS, Vincent WJ, Perez VL, Cruz-Guilloty F, Kao WW, Call MK, Tucker BA, Zhan Q, Murphy GF, Lathrop KL, Alt C, Mortensen LJ, Lin CP, Zieske JD, Frank MH, Frank NY. ABCB5 is a limbal stem cell gene required for corneal development and repair. Nature. 2014 Jul 17; 511(7509):353-7. PMID: 25030174.
    Citations: 101     Fields:    Translation:HumansAnimalsCells
  42. Wilson BJ, Saab KR, Ma J, Schatton T, Pütz P, Zhan Q, Murphy GF, Gasser M, Waaga-Gasser AM, Frank NY, Frank MH. ABCB5 maintains melanoma-initiating cells through a proinflammatory cytokine signaling circuit. Cancer Res. 2014 Aug 01; 74(15):4196-207. PMID: 24934811.
    Citations: 62     Fields:    Translation:HumansAnimalsCells
  43. Volpicelli ER, Lezcano C, Zhan Q, Girouard SD, Kindelberger DW, Frank MH, Frank NY, Crum CP, Murphy GF. The multidrug-resistance transporter ABCB5 is expressed in human placenta. Int J Gynecol Pathol. 2014 Jan; 33(1):45-51. PMID: 24300535.
    Citations: 7     Fields:    Translation:HumansCells
  44. Timerman D, Frank NY. Novel double heterozygous mutations in MEFV and NLRP3 genes in a patient with familial Mediterranean fever. J Clin Rheumatol. 2013 Dec; 19(8):452-3. PMID: 24263150.
    Citations: 4     Fields:    Translation:Humans
  45. Murphy GF, Wilson BJ, Girouard SD, Frank NY, Frank MH. Stem cells and targeted approaches to melanoma cure. Mol Aspects Med. 2014 Oct; 39:33-49. PMID: 24145241.
    Citations: 27     Fields:    Translation:HumansAnimalsCells
  46. Lin JY, Zhang M, Schatton T, Wilson BJ, Alloo A, Ma J, Qureshi AA, Frank NY, Han J, Frank MH. Genetically determined ABCB5 functionality correlates with pigmentation phenotype and melanoma risk. Biochem Biophys Res Commun. 2013 Jul 05; 436(3):536-42. PMID: 23770371.
    Citations: 8     Fields:    Translation:HumansCells
  47. Wilson BJ, Schatton T, Zhan Q, Gasser M, Ma J, Saab KR, Schanche R, Waaga-Gasser AM, Gold JS, Huang Q, Murphy GF, Frank MH, Frank NY. ABCB5 identifies a therapy-refractory tumor cell population in colorectal cancer patients. Cancer Res. 2011 Aug 01; 71(15):5307-16. PMID: 21652540.
    Citations: 62     Fields:    Translation:HumansAnimals
  48. Wilson BJ, Schatton T, Frank MH, Frank NY. Colorectal Cancer Stem Cells: Biology and Therapeutic Implications. Curr Colorectal Cancer Rep. 2011 Jun; 7(2):128-135. PMID: 21552371.
    Citations: 22     
  49. Frank NY, Schatton T, Kim S, Zhan Q, Wilson BJ, Ma J, Saab KR, Osherov V, Widlund HR, Gasser M, Waaga-Gasser AM, Kupper TS, Murphy GF, Frank MH. VEGFR-1 expressed by malignant melanoma-initiating cells is required for tumor growth. Cancer Res. 2011 Feb 15; 71(4):1474-85. PMID: 21212411.
    Citations: 86     Fields:    Translation:HumansAnimalsCells
  50. Ma J, Lin JY, Alloo A, Wilson BJ, Schatton T, Zhan Q, Murphy GF, Waaga-Gasser AM, Gasser M, Stephen Hodi F, Frank NY, Frank MH. Isolation of tumorigenic circulating melanoma cells. Biochem Biophys Res Commun. 2010 Nov 26; 402(4):711-7. PMID: 20977885.
    Citations: 32     Fields:    Translation:HumansAnimalsCells
  51. Izawa A, Schatton T, Frank NY, Ueno T, Yamaura K, Pendse SS, Margaryan A, Grimm M, Gasser M, Waaga-Gasser AM, Sayegh MH, Frank MH. A novel in vivo regulatory role of P-glycoprotein in alloimmunity. Biochem Biophys Res Commun. 2010 Apr 09; 394(3):646-52. PMID: 20230790; PMCID: PMC3756468.
    Citations: 5     Fields:    Translation:AnimalsCells
  52. Schatton T, Schütte U, Frank NY, Zhan Q, Hoerning A, Robles SC, Zhou J, Hodi FS, Spagnoli GC, Murphy GF, Frank MH. Modulation of T-cell activation by malignant melanoma initiating cells. Cancer Res. 2010 Jan 15; 70(2):697-708. PMID: 20068175.
    Citations: 138     Fields:    Translation:HumansAnimalsCells
  53. Frank NY, Schatton T, Frank MH. The therapeutic promise of the cancer stem cell concept. J Clin Invest. 2010 Jan; 120(1):41-50. PMID: 20051635; PMCID: PMC2798700.
    Citations: 298     Fields:    Translation:HumansAnimalsCells
  54. Schatton T, Frank NY, Frank MH. Identification and targeting of cancer stem cells. Bioessays. 2009 Oct; 31(10):1038-49. PMID: 19708024.
    Citations: 72     Fields:    Translation:HumansAnimalsCells
  55. Frank NY, Frank MH. ABCB5 gene amplification in human leukemia cells. Leuk Res. 2009 Oct; 33(10):1303-5. PMID: 19477512.
    Citations: 9     Fields:    Translation:HumansCells
  56. Schatton T, Frank NY, Frank MH. . Solid tumor stem cells – implications for cancer therapy. Regulatory Networks in Stem Cells. Ed. by V.K. Rajasekhar and M.C. Vemuri. 2009.
  57. Schatton T, Murphy GF, Frank NY, Yamaura K, Waaga-Gasser AM, Gasser M, Zhan Q, Jordan S, Duncan LM, Weishaupt C, Fuhlbrigge RC, Kupper TS, Sayegh MH, Frank MH. Identification of cells initiating human melanomas. Nature. 2008 Jan 17; 451(7176):345-9. PMID: 18202660.
    Citations: 574     Fields:    Translation:HumansAnimalsCells
  58. Frank NY, Kho AT, Schatton T, Murphy GF, Molloy MJ, Zhan Q, Ramoni MF, Frank MH, Kohane IS, Gussoni E. Regulation of myogenic progenitor proliferation in human fetal skeletal muscle by BMP4 and its antagonist Gremlin. J Cell Biol. 2006 Oct 09; 175(1):99-110. PMID: 17015616; PMCID: PMC2064502.
    Citations: 33     Fields:    Translation:HumansCells
  59. Muskiewicz KR, Frank NY, Flint AF, Gussoni E. Myogenic potential of muscle side and main population cells after intravenous injection into sub-lethally irradiated mdx mice. J Histochem Cytochem. 2005 Jul; 53(7):861-73. PMID: 15995145.
    Citations: 14     Fields:    Translation:AnimalsCellsPHPublic Health
  60. Frank NY, Margaryan A, Huang Y, Schatton T, Waaga-Gasser AM, Gasser M, Sayegh MH, Sadee W, Frank MH. ABCB5-mediated doxorubicin transport and chemoresistance in human malignant melanoma. Cancer Res. 2005 May 15; 65(10):4320-33. PMID: 15899824.
    Citations: 211     Fields:    Translation:HumansCells
  61. Rigol N, Frank NY, Margaryan A, Schatton T, Frank MH. . Differential expression of ABCB5 multidrug resistance P-glycoprotein in human breast cancer cell lines. June 8-11, Abstract P66-7. 2005; 467.
  62. Frank, NY, Tishler P. . Chapter 16: Congentinal, metabolic and neuromuscular disorders in Respiratory Genetics. Ed. By Silverman, Weiss & Shapiro. 2005.
  63. Frank NY, Margaryan A, Huang Y, Waaga-Gasser AM, Gasser M, Sayegh MH, Sadee W, Frank MH. . ABCB5-mediated doxorubicin transport and chemoresistance in human malignant melanoma. American Association for Cancer Research 96th Annual Meeting, April 16-20,. 2005.
  64. Frank N, Frank MH, Gussoni E. . ABCB5 P-glycoprotein is a molecular marker of the Hoechst 33342 side population phenotype among human fetal skeletal muscle cells. The FASEB Journal (oral presentation). 2004; 18(4):A183.
  65. Frank NY, Pendse SS, Lapchak PH, Margaryan A, Shlain D, Doeing C, Sayegh MH, Frank MH. Regulation of progenitor cell fusion by ABCB5 P-glycoprotein, a novel human ATP-binding cassette transporter. J Biol Chem. 2003 Nov 21; 278(47):47156-65. PMID: 12960149.
    Citations: 98     Fields:    Translation:HumansCells
  66. Frank NY, Pendse S, Lapchak PH, Doeing C, Sayegh MH, Frank MH. . Regulation of progenitor cell fusion by ABCB5 P-glycoprotein, a novel human ATP-binding cassette transporter. American Journal of Human Genetics. 2003; 73(5 Supplement):327.
  67. Melnik (Frank) N, Yutzey KE, Gannon M, Bader D. . Commitment, differentiation, and diversification of avian cardiac progenitor cells. Ann N Y Acad Sci. 1995; (752):1-8.
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.