Associate Professor in the Department of Biostatistics
Harvard T.H. Chan School of Public Health
Harvard School of Public Health
655 Huntington Ave
Boston MA 02115
Member of the Faculty of Pediatrics
Boston Children's Hospital
Post-Doctoral Fellow in Statistics
Faculty of Arts & Sciences
2008 - 2010
Claudia Adams Barr Award
2010 - 2011
Career Incubator Award
We develop computational method to analyze and integrate various data-types. Our long-term goal is to characterize the structure and dynamics of gene regulatory networks in order to mechanistic insights into the maintenance of cell-type identity. We apply this knowledge to investigate the etiology of cancer and other diseases.
Current research topics involving new statistical methodologies include: 1) targeting mechanisms for epigenetic factors; 2) multi-level spatial organization of chromatin states; 3) gene regulatory network reconstruction; 4) single cell level gene expression;.
Application areas include: 1) role of epigenetics in cancer and other diseases. 2) cancer pathways and networks; 3) stem cells maintenance and cell differentiation
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