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Neil Gupta, M.D.

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Biography
University of Pennsylvania, PhiladelphiaMD05/2007Medicine
Harvard School of Public Health, BostonMPH05/2012Public Health
Duke University, Durham, NCBS05/2002Neuroscience

Overview
Dr. Gupta is an internist, pediatrician, and public health specialist, and currently serves as Clinical Director for the NCD Synergies Project and the Lancet Commission for Reframing NCDs and Injuries for the Poorest Billion. He has previously worked as Chief Medical Officer for Partners In Health in Rwanda, where he was responsible for the strategy, design, and implementation of clinical programs provided in collaboration with the Ministry of Health. Dr. Gupta is Primary Investigator for the Simplifying Hepatitis C Antiviral Therapy for Elsewhere in the Developing World study, which aims to demonstrated safety and effectiveness of direct-acting antiviral treatment for Hepatitis C in Rwanda and develop treatment models for care. Previously, he served as Primary Investigator for the Population Health Implementation & Training grant, which implemented and then measured the impact of a comprehensive clinical and training program in rural Rwanda. Dr. Gupta is a graduate of University of Pennsylvania School of Medicine and Harvard School of Public Health, and he completed his residency training at Brigham & Women’s and Boston Children’s Hospitals. He is currently based in Addis Ababa, Ethiopia.

Dr. Gupta’s research focus is on the treatment outcomes of chronic hepatitis C infection in Rwanda. Through the Simplifying Hepatitis C Antiviral Therapy for Elsewhere in the Developing World (SHARED) study, Dr. Gupta’s team is evaluating the safety and efficacy of direct-acting antiviral (DAA) treatment in Rwanda. The study will also evaluate the epidemiology of hepatitis C infection in Rwanda, qualitatively explore the treatment experience of individual patients, and determine risk factors for treatment failure. The study will use outcomes of the study to develop simplified models for decentralized hepatitis C care delivery and promote greater access to DAAs in low-income countries. Dr. Gupta also studies the state of health service delivery for non-communicable diseases and injuries (NCDIs) in several countries throughout sub-Saharan Africa and South Asia supporting national NCD policy, planning, and advocacy. Through the Program in Global Noncommunicable Disease and Social Change, he has led the establishment and coordination of national NCDI Poverty Commissions to research the links between NCDIs and poverty and to plan for health sector interventions to address these challenges. Dr. Gupta has previously led operational research of outcomes of a large community-based HIV care and treatment program in rural Rwanda.

Bibliographic
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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  1. Rutayisire R, Mutabazi F, Bayingana A, Miller AC, Gupta N, Ngoga G, Ngabireyimana E, Borg R, Rusingiza E, Bavuma C, Bigirimana B, Nkikabahizi F, Muhimpundu MA, Bukhman G, Park PH. Integration of Chronic Oncology Services in Noncommunicable Disease Clinic in Rural Rwanda. Ann Glob Health. 2020 Mar 23; 86(1):33. PMID: 32257833.
    Citations:    
  2. Grant P, Shumbusho F, Van Nuil JI, Kateera F, Mukherjee J, Kabahizi J, Ntaganda F, Nsanzimana S, Mbituyumuremyi A, Damascene MJ, Muvunyi CM, Mukabatsinda C, Musabeyezu E, Ntirenganya C, Gupta N. Safety and Efficacy of Limited Laboratory Monitoring for Hepatitis C Treatment: A Blinded Clinical Trial in Rwanda. Hepatol Commun. 2020 Apr; 4(4):569-576. PMID: 32258951.
    Citations:    
  3. Gupta N, Kateera F, Desalegn H, Ocama P, Njouom R, Lacombe K. Is resistance to direct-acting antivirals in sub-Saharan Africa a threat to HCV elimination? Recommendations for action. J Hepatol. 2020 Mar; 72(3):583-584. PMID: 31836263.
    Citations:    
  4. Makuza JD, Liu CY, Ntihabose CK, Dushimiyimana D, Umuraza S, Nisingizwe MP, Umutesi J, Serumondo J, Mugeni SD, Semakula M, Gupta N, Hellard M, Nsanzimana S. Risk factors for viral hepatitis C infection in Rwanda: results from a nationwide screening program. BMC Infect Dis. 2019 Aug 05; 19(1):688. PMID: 31382901.
    Citations:    
  5. Umutesi J, Liu CY, Penkunas MJ, Makuza JD, Ntihabose CK, Umuraza S, Niyikora J, Serumondo J, Gupta N, Nsanzimana S. Screening a nation for hepatitis C virus elimination: a cross-sectional study on prevalence of hepatitis C and associated risk factors in the Rwandan general population. BMJ Open. 2019 07 03; 9(7):e029743. PMID: 31272986.
    Citations:    
  6. Roder-DeWan S, Gupta N, Kagabo DM, Habumugisha L, Nahimana E, Mugeni C, Bucyana T, Hirschhorn LR. Four delays of child mortality in Rwanda: a mixed methods analysis of verbal social autopsies. BMJ Open. 2019 05 27; 9(5):e027435. PMID: 31133592.
    Citations:    
  7. Umutesi G, Shumbusho F, Kateera F, Serumondo J, Kabahizi J, Musabeyezu E, Ngwije A, Gupta N, Nsanzimana S. Rwanda launches a 5-year national hepatitis C elimination plan: A landmark in sub-Saharan Africa. J Hepatol. 2019 06; 70(6):1043-1045. PMID: 30948269.
    Citations:    
  8. Gupta N, Hirschhorn LR, Rwabukwisi FC, Drobac P, Sayinzoga F, Mugeni C, Nkikabahizi F, Bucyana T, Magge H, Kagabo DM, Nahimana E, Rouleau D, VanderZanden A, Murray M, Amoroso C. Causes of death and predictors of childhood mortality in Rwanda: a matched case-control study using verbal social autopsy. BMC Public Health. 2018 Dec 17; 18(1):1378. PMID: 30558586.
    Citations:    Fields:    
  9. Gupta N, Mbituyumuremyi A, Kabahizi J, Ntaganda F, Muvunyi CM, Shumbusho F, Musabeyezu E, Mukabatsinda C, Ntirenganya C, Van Nuil JI, Kateera F, Camus G, Damascene MJ, Nsanzimana S, Mukherjee J, Grant PM. Treatment of chronic hepatitis C virus infection in Rwanda with ledipasvir-sofosbuvir (SHARED): a single-arm trial. Lancet Gastroenterol Hepatol. 2019 02; 4(2):119-126. PMID: 30552056.
    Citations:    Fields:    
  10. Nyishime M, Borg R, Ingabire W, Hedt-Gauthier B, Nahimana E, Gupta N, Hansen A, Labrecque M, Nkikabahizi F, Mutaganzwa C, Biziyaremye F, Mukayiranga C, Mwamini F, Magge H. A retrospective study of neonatal case management and outcomes in rural Rwanda post implementation of a national neonatal care package for sick and small infants. BMC Pediatr. 2018 11 12; 18(1):353. PMID: 30419867.
    Citations:    Fields:    
  11. Dusengimana JMV, Hategekimana V, Borg R, Hedt-Gauthier B, Gupta N, Troyan S, Shulman LN, Nzayisenga I, Fadelu T, Mpunga T, Pace LE. Pregnancy-associated breast cancer in rural Rwanda: the experience of the Butaro Cancer Center of Excellence. BMC Cancer. 2018 Jun 05; 18(1):634. PMID: 29866062.
    Citations:    Fields:    
  12. Gupta N, Nsanzimana S. Is hepatitis C elimination possible in sub-Saharan Africa? The case of Rwanda. Lancet Gastroenterol Hepatol. 2018 May; 3(5):302-303. PMID: 29644975.
    Citations:    
  13. Abimpaye M, Kirk CM, Iyer HS, Gupta N, Remera E, Mugwaneza P, Law MR. The impact of "Option B" on HIV transmission from mother to child in Rwanda: An interrupted time series analysis. PLoS One. 2018; 13(2):e0192910. PMID: 29451925.
    Citations:    Fields:    Translation:HumansCells
  14. Kagabo DM, Kirk CM, Bakundukize B, Hedt-Gauthier BL, Gupta N, Hirschhorn LR, Ingabire WC, Rouleau D, Nkikabahizi F, Mugeni C, Sayinzoga F, Amoroso CL. Care-seeking patterns among families that experienced under-five child mortality in rural Rwanda. PLoS One. 2018; 13(1):e0190739. PMID: 29320556.
    Citations: 1     Fields:    Translation:Humans
  15. Rothman J, Kayigamba F, Hills V, Gupta N, Machara F, Niyigena P, Franke MF. The Impact of a Community-Based Intervention Including a Monthly Food Ration on Food Insecurity Among HIV-Positive Adults During the First Year of Antiretroviral Therapy. AIDS Behav. 2018 01; 22(1):154-163. PMID: 28849289.
    Citations:    Fields:    
  16. Munyaneza F, Ntaganira J, Nyirazinyoye L, Birru E, Nisingizwe MP, Gupta N, Amoroso CL, Neza G, Hirschhorn LR, Hedt-Gauthier BL. Community-Based Accompaniment and the Impact of Distance for HIV Patients Newly Initiated on Antiretroviral Therapy: Early Outcomes and Clinic Visit Adherence in Rural Rwanda. AIDS Behav. 2018 01; 22(1):77-85. PMID: 28025738.
    Citations: 1     Fields:    
  17. Mbituyumuremyi A, Van Nuil JI, Umuhire J, Mugabo J, Mwumvaneza M, Makuza JD, Umutesi J, Nsanzimana S, Gupta N. Controlling hepatitis C in Rwanda: a framework for a national response. Bull World Health Organ. 2018 Jan 01; 96(1):51-58. PMID: 29403100.
    Citations:    Fields:    Translation:HumansPHPublic Health
  18. Navale S, Habumugisha L, Amoroso C, Sayinzoga F, Gupta N, Hirschhorn LR. Exploring Drivers of Infant Deaths in Rural Rwanda Through Verbal Social Autopsy. Ann Glob Health. 2017 Sep - Dec; 83(5-6):756-766. PMID: 29248092.
    Citations:    Fields:    Translation:Humans
  19. Gupta N, Kabahizi J, Mukabatsinda C, Walker TD, Musabeyezu E, Kiromera A, Van Nuil JI, Steiner K, Mukherjee J, Nsanzimana S, Mbituyumuremyi A. "Waiting for DAAs": A retrospective chart review of patients with untreated hepatitis C in Rwanda. PLoS One. 2017; 12(3):e0174148. PMID: 28323868.
    Citations:    Fields:    Translation:HumansCells
  20. Mutagoma M, Samuel MS, Kayitesi C, Gasasira AR, Chitou B, Boer K, Hedt-Gauthier B, Gupta N, Ntaganira J, Nsanzimana S. High HIV prevalence and associated risk factors among female sex workers in Rwanda. Int J STD AIDS. 2017 Oct; 28(11):1082-1089. PMID: 28081683.
    Citations: 2     Fields:    Translation:Humans
  21. Guillaine N, Mwizerwa W, Odhiambo J, Hedt-Gauthier BL, Hirschhorn LR, Mugwaneza P, Umugisha JP, Cyamatare FR, Mutaganzwa C, Gupta N. A Novel Combined Mother-Infant Clinic to Optimize Post-Partum Maternal Retention, Service Utilization, and Linkage to Services in HIV Care in Rural Rwanda. Int J MCH AIDS. 2017; 6(1):36-45. PMID: 28798892.
    Citations:    
  22. Nahimana E, McBain R, Manzi A, Iyer H, Uwingabiye A, Gupta N, Muzungu G, Drobac P, Hirschhorn LR. Race to the Top: evaluation of a novel performance-based financing initiative to promote healthcare delivery in rural Rwanda. Glob Health Action. 2016; 9:32943. PMID: 27900933.
    Citations: 4     Fields:    
  23. Cyamatare Rwabukwisi F, Hedt-Gauthier BL, Ribakare M, Mukamana J, Gatesi Y, Stulac S, Drobac P, Amoroso CL, Gupta N. Five-year Outcomes Among Children Receiving Antiretroviral Therapy in a Community-based Accompaniment Program in Rural Rwanda. Pediatr Infect Dis J. 2016 Nov; 35(11):1222-1224. PMID: 27753767.
    Citations:    Fields:    
  24. Nkurunziza T, Toma G, Odhiambo J, Maine R, Riviello R, Gupta N, Habiyakare C, Mpunga T, Bonane A, Hedt-Gauthier B. Referral patterns and predictors of referral delays for patients with traumatic injuries in rural Rwanda. Surgery. 2016 12; 160(6):1636-1644. PMID: 27743716.
    Citations: 3     Fields:    Translation:Humans
  25. Muhirwa E, Habiyakare C, Hedt-Gauthier BL, Odhiambo J, Maine R, Gupta N, Toma G, Nkurunziza T, Mpunga T, Mukankusi J, Riviello R. Non-Obstetric Surgical Care at Three Rural District Hospitals in Rwanda: More Human Capacity and Surgical Equipment May Increase Operative Care. World J Surg. 2016 Sep; 40(9):2109-16. PMID: 27098541.
    Citations: 4     Fields:    Translation:Humans
  26. Mutagoma M, Balisanga H, Remera E, Gupta N, Malamba SS, Riedel DJ, Nsanzimana S. Ten-year trends of syphilis in sero-surveillance of pregnant women in Rwanda and correlates of syphilis-HIV co-infection. Int J STD AIDS. 2017 01; 28(1):45-53. PMID: 26692548.
    Citations:    Fields:    Translation:HumansPHPublic Health
  27. Cyamatare FR, Hedt-Gauthier BL, Ribakare M, Mukamana J, Gatesi Y, Stulac S, Drobac P, Amoroso CL, Gupta N. Five-Year Outcomes Among Children Receiving Antiretroviral Therapy in a Community-Based Accompaniment Program in Rural Rwanda. Pediatr Infect Dis J. 2016 Jun 16. PMID: 27314824.
    Citations:    Fields:    
  28. Gupta N, Munyaburanga C, Mutagoma M, Niyigena JW, Kayigamba F, Franke MF, Hedt-Gauthier B. Community-Based Accompaniment Mitigates Predictors of Negative Outcomes for Adults on Antiretroviral Therapy in Rural Rwanda. AIDS Behav. 2016 05; 20(5):1009-16. PMID: 26346334.
    Citations: 4     Fields:    Translation:HumansCells
  29. Nahimana E, McBain R, Manzi A, Iyer H, Uwingabiye A, Gupta N, Muzungu G, Drobac P, Hirschhorn LR. Race to the Top: evaluation of a novel performance-based financing initiative to promote healthcare delivery in rural Rwanda. Glob Health Action. 2016 Jan; 9(1):32943. PMID: 28156995.
    Citations:    
  30. Gupta N, Bukhman G. Leveraging the lessons learned from HIV/AIDS for coordinated chronic care delivery in resource-poor settings. Healthc (Amst). 2015 Dec; 3(4):215-20. PMID: 26699346.
    Citations: 5     Fields:    Translation:Humans
  31. Bukhman G, Bavuma C, Gishoma C, Gupta N, Kwan GF, Laing R, Beran D. Endemic diabetes in the world's poorest people. Lancet Diabetes Endocrinol. 2015 Jun; 3(6):402-403. PMID: 26003752.
    Citations: 3     Fields:    Translation:HumansPHPublic Health
  32. Karema N, Manzi A, Gaju E, Kayiganwa M, Remera E, Nshimyiryo A, Niyibizi G, Dukuze A, Gupta N, Amoroso C. Using Electronic Medical Record Data to Improve HIV Patient Monitoring, Clinical Decision-Making, and Quality Improvement: Lessons from Rwanda. Stud Health Technol Inform. 2015; 216:880. PMID: 26262182.
    Citations: 1     Fields:    Translation:Humans
  33. Mutagoma M, Kayitesi C, Gwiza A, Ruton H, Koleros A, Gupta N, Balisanga H, Riedel DJ, Nsanzimana S. Estimation of the size of the female sex worker population in Rwanda using three different methods. Int J STD AIDS. 2015 Oct; 26(11):810-4. PMID: 25336306.
    Citations: 1     Fields:    Translation:Humans
  34. Vasan A, Ellner A, Lawn SD, Gove S, Anatole M, Gupta N, Drobac P, Nicholson T, Seung K, Mabey DC, Farmer PE. Integrated care as a means to improve primary care delivery for adults and adolescents in the developing world: a critical analysis of Integrated Management of Adolescent and Adult Illness (IMAI). BMC Med. 2014 Jan 14; 12:6. PMID: 24423387.
    Citations: 9     Fields:    Translation:Humans
  35. Vasan A, Anatole M, Mezzacappa C, Hedt-Gauthier BL, Hirschhorn LR, Nkikabahizi F, Hagenimana M, Ndayisaba A, Cyamatare FR, Nzeyimana B, Drobac P, Gupta N. Baseline assessment of adult and adolescent primary care delivery in Rwanda: an opportunity for quality improvement. BMC Health Serv Res. 2013 Dec 17; 13:518. PMID: 24344805.
    Citations: 3     Fields:    Translation:Humans
  36. Vasan A, Ellner A, Lawn SD, Gupta N, Anatole M, Drobac P, Nicholson T, Gove S, Seung K, Mabey D, Farmer P. Strengthening of primary-care delivery in the developing world: IMAI and the need for integrated models of care. Lancet Glob Health. 2013 Dec; 1(6):e321-3. PMID: 25104589.
    Citations: 2     Fields:    Translation:Humans
  37. Gupta N, Cyamatare FR, Niyigena P, Niyigena JW, Stulac S, Mugwaneza P, Drobac P, Rich M, Franke MF. Clinical outcomes of a comprehensive integrated program for HIV-exposed infants: a 3-year experience promoting HIV-free survival in rural Rwanda. J Acquir Immune Defic Syndr. 2013 Apr 01; 62(4):e109-14. PMID: 23202811.
    Citations: 3     Fields:    Translation:Humans
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