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Rodrigo Benedetti Gassen, Ph.D.


Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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  1. Gassen RB, Borges TJ, Pérez-Sáez MJ, Zhang H, Al Jurdi A, Llinàs-Mallol L, Aoyama B, Lima M, Pascual J, Sage PT, Murakami N, Riella LV. T cell depletion increases humoral response by favoring T follicular helper cells expansion. Am J Transplant. 2022 07; 22(7):1766-1778. PMID: 35320600; PMCID: PMC9262847.
    Citations:    Fields:    Translation:AnimalsCells
  2. Al Jurdi A, Gassen RB, Borges TJ, Lape IT, Morena L, Efe O, Solhjou Z, El Fekih R, Deban C, Bohan B, Pattanayak V, Kotton CN, Azzi JR, Riella LV. Suboptimal antibody response against SARS-CoV-2 Omicron variant after third dose of mRNA vaccine in kidney transplant recipients. Kidney Int. 2022 06; 101(6):1282-1286. PMID: 35429496; PMCID: PMC9006415.
    Citations:    Fields:    Translation:HumansCells
  3. Borges TJ, Abarzua P, Gassen RB, Kollar B, Lima-Filho M, Aoyama BT, Gluhova D, Clark RA, Islam SA, Pomahac B, Murphy GF, Lian CG, Talbot SG, Riella LV. T cell-attracting CCL18 chemokine is a dominant rejection signal during limb transplantation. Cell Rep Med. 2022 03 15; 3(3):100559. PMID: 35492875; PMCID: PMC9040185.
    Citations:    Fields:    Translation:Humans
  4. Al Jurdi A, Gassen RB, Borges TJ, Solhjou Z, Hullekes FE, Lape IT, Efe O, Alghamdi A, Patel P, Choi JY, Mohammed MT, Bohan B, Pattanayak V, Rosales I, Cravedi P, Kotton CN, Azzi JR, Riella LV. Non-Invasive Monitoring for Rejection in Kidney Transplant Recipients After SARS-CoV-2 mRNA Vaccination. Front Immunol. 2022; 13:838985. PMID: 35281011; PMCID: PMC8913529.
    Citations: 1     Fields:    Translation:HumansCellsPHPublic Health
  5. Borges TJ, Murakami N, Lape IT, Gassen RB, Liu K, Cai S, Daccache J, Safa K, Shimizu T, Ohori S, Paterson AM, Cravedi P, Azzi J, Sage PT, Sharpe AH, Li XC, Riella LV. Overexpression of PD-1 on T cells promotes tolerance in cardiac transplantation via ICOS-dependent mechanisms. JCI Insight. 2021 12 22; 6(24). PMID: 34752418; PMCID: PMC8783692.
    Citations: 1     Fields:    Translation:HumansAnimalsCells
  6. Fazolo T, Lima K, Fontoura JC, de Souza PO, Hilario G, Zorzetto R, Júnior LR, Pscheidt VM, de Castilhos Ferreira Neto J, Haubert AF, Gambin I, Oliveira AC, Mello RS, de Bastos Balbe E Gutierres M, Gassen RB, Coimbra LD, Borin A, Marques RE, Sartor ITS, Zavaglia GO, Fernandes IR, Nakaya HI, Varela FH, Polese-Bonatto M, Borges TJ, Callegari-Jacques SM, da Costa MSC, de Araujo Schwartz J, Scotta MC, Stein RT, Bonorino C. Pediatric COVID-19 patients in South Brazil show abundant viral mRNA and strong specific anti-viral responses. Nat Commun. 2021 11 25; 12(1):6844. PMID: 34824230.
    Citations: 5     Fields:    Translation:HumansCells
  7. de Freitas DDN, Marinho Franceschina C, Muller D, Hilario GT, Gassen RB, Fazolo T, de Lima Kaminski V, Bogo Chies JA, Maito F, Antunes KH, Zanin RF, Rodrigues LC, Duarte de Souza AP. RvD1 treatment during primary infection modulates memory response increasing viral load during respiratory viral reinfection. Immunobiology. 2021 11; 226(6):152151. PMID: 34742024.
    Citations:    Fields:    Translation:HumansAnimalsCells
  8. Gassen RB, Fazolo T, Nascimento de Freitas D, Borges TJ, Lima K, Antunes GL, Maito F, Bueno Mendes DA, Báfica A, Rodrigues LC, Stein R, Duarte de Souza AP, Bonorino C. IL-21 treatment recovers follicular helper T cells and neutralizing antibody production in respiratory syncytial virus infection. Immunol Cell Biol. 2021 03; 99(3):309-322. PMID: 33068449.
    Citations: 4     Fields:    Translation:AnimalsCells
  9. da Silva EFG, Lima KG, Krause GC, Haute GV, Pedrazza L, Catarina AV, Gassen RB, de Souza Basso B, Dias HB, Luft C, Garcia MCR, Costa BP, Antunes GL, Basso LA, Donadio MVF, Machado P, de Oliveira JR. CPBMF65, a synthetic human uridine phosphorylase-1 inhibitor, reduces HepG2 cell proliferation through cell cycle arrest and senescence. Invest New Drugs. 2020 12; 38(6):1653-1663. PMID: 32367200.
    Citations:    Fields:    Translation:HumansCells
  10. Zhao Y, Lee CK, Lin CH, Gassen RB, Xu X, Huang Z, Xiao C, Bonorino C, Lu LF, Bui JD, Hui E. PD-L1:CD80 Cis-Heterodimer Triggers the Co-stimulatory Receptor CD28 While Repressing the Inhibitory PD-1 and CTLA-4 Pathways. Immunity. 2019 12 17; 51(6):1059-1073.e9. PMID: 31757674.
    Citations: 82     Fields:    Translation:HumansAnimalsCells
  11. Silveira JS, Antunes GL, Gassen RB, Breda RV, Stein RT, Pitrez PM, da Cunha AA. Respiratory syncytial virus increases eosinophil extracellular traps in a murine model of asthma. Asia Pac Allergy. 2019 Oct; 9(4):e32. PMID: 31720243; PMCID: PMC6826116.
    Citations: 7     
  12. Krause GC, Lima KG, Levorse V, Haute GV, Gassen RB, Garcia MC, Pedrazza L, Donadio MVF, Luft C, de Oliveira JR. Exenatide induces autophagy and prevents the cell regrowth in HepG2 cells. EXCLI J. 2019; 18:540-548. PMID: 31611738; PMCID: PMC6785771.
    Citations: 4     
  13. Silveira JS, Antunes GL, Kaiber DB, da Costa MS, Ferreira FS, Marques EP, Schmitz F, Gassen RB, Breda RV, Wyse ATS, Stein RT, Pitrez PM, da Cunha AA. Autophagy induces eosinophil extracellular traps formation and allergic airway inflammation in a murine asthma model. J Cell Physiol. 2020 01; 235(1):267-280. PMID: 31206674.
    Citations: 18     Fields:    Translation:AnimalsCells
  14. Silveira JS, Antunes GL, Kaiber DB, da Costa MS, Marques EP, Ferreira FS, Gassen RB, Breda RV, Wyse ATS, Pitrez P, da Cunha AA. Reactive oxygen species are involved in eosinophil extracellular traps release and in airway inflammation in asthma. J Cell Physiol. 2019 12; 234(12):23633-23646. PMID: 31180592.
    Citations: 10     Fields:    Translation:AnimalsCells
  15. Fazolo T, Gassen RB, de Freitas DN, Borges TJ, Rigo MM, da Silva RD, Maito F, Cunha A, Gasparin Bueno Mendes DA, Báfica A, Vargas JE, de Souza APD, Bonorino C. Vaccination with RSV M209-223 peptide promotes a protective immune response associated with reduced pulmonary inflammation. Antiviral Res. 2018 09; 157:102-110. PMID: 29990516.
    Citations:    Fields:    Translation:AnimalsCells
  16. Lima KG, Krause GC, da Silva EFG, Xavier LL, Martins LAM, Alice LM, da Luz LB, Gassen RB, Filippi-Chiela EC, Haute GV, Garcia MCR, Funchal GA, Pedrazza L, Reghelin CK, de Oliveira JR. Octyl gallate reduces ATP levels and Ki67 expression leading HepG2 cells to cell cycle arrest and mitochondria-mediated apoptosis. Toxicol In Vitro. 2018 Apr; 48:11-25. PMID: 29288082.
    Citations: 8     Fields:    Translation:HumansCells
  17. da Luz Dias R, Basso B, Donadio MVF, Pujol FV, Bartrons R, Haute GV, Gassen RB, Bregolin HD, Krause G, Viau C, Saffi J, Nunes FB, Rosa JL, de Oliveira JR. Leucine reduces the proliferation of MC3T3-E1 cells through DNA damage and cell senescence. Toxicol In Vitro. 2018 Apr; 48:1-10. PMID: 29278758.
    Citations: 3     Fields:    Translation:AnimalsCells
  18. Krause GC, Lima KG, Dias HB, da Silva EFG, Haute GV, Basso BS, Gassen RB, Marczak ES, Nunes RSB, de Oliveira JR. Liraglutide, a glucagon-like peptide-1 analog, induce autophagy and senescence in HepG2 cells. Eur J Pharmacol. 2017 Aug 15; 809:32-41. PMID: 28501576.
    Citations: 8     Fields:    Translation:HumansAnimalsCells
  19. Pedrazza L, Cunha AA, Luft C, Nunes NK, Schimitz F, Gassen RB, Breda RV, Donadio MV, de Souza Wyse AT, Pitrez PMC, Rosa JL, de Oliveira JR. Mesenchymal stem cells improves survival in LPS-induced acute lung injury acting through inhibition of NETs formation. J Cell Physiol. 2017 12; 232(12):3552-3564. PMID: 28112391.
    Citations: 42     Fields:    Translation:AnimalsCells
  20. do Nascimento de Freitas D, Gassen RB, Fazolo T, Souza APD. Rapamycin increases RSV RNA levels and survival of RSV-infected dendritic cell depending on T cell contact. Toxicol In Vitro. 2016 Oct; 36:114-119. PMID: 27466155.
    Citations: 4     Fields:    Translation:AnimalsCells
  21. Gassen RB, Romão PR, Freitas DN, Rodrigues Junior LC. Construction and Functional Characterization of a Fusion Protein Interleukin-21/Immunoglobulin for Long-Term In Vivo Biodisponibility. DNA Cell Biol. 2016 Mar; 35(3):146-55. PMID: 26720885.
    Citations:    Fields:    Translation:HumansAnimalsCells
  22. Freitas DN, Isaía HA, Henzel A, Simão E, Gassen RB, Rodrigues Junior LC. Comparative study of lymphocytes from individuals that were vaccinated and unvaccinated against the pandemic 2009-2011 H1N1 influenza virus in Southern Brazil. Rev Soc Bras Med Trop. 2015 Sep-Oct; 48(5):514-23. PMID: 26516959.
    Citations: 1     Fields:    Translation:HumansCellsPHPublic Health
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.