Harvard Catalyst Profiles

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Nirmal Shyam Sharma, M.D.

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Stanley Medical College, IndiaMedicine
NEOMED, OHInternshipInternal Medicine
Albert Einstein College of Medicine, NYResidencyInternal Medicine
University of Alabama at Birmingham, ALFellowship Pulmonary and Critical Care Medicine
University of Alabama at Birmingham, ALInstructorLung Transplantation & Mechanical Circulatory Support

The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
  1. 1R01HL161620-01A1 (Sharma, Nirmal) Jul 1, 2022 - Jun 30, 2027
    Microbial Dysbiosis in Chronic Lung Allograft Dysfunction
    Role: PI

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Maron BA, Kleiner DE, Arons E, Wertheim BM, Sharma NS, Haley KJ, Samokhin AO, Rowin EJ, Maron MS, Rosing DR, Maron BJ. Evidence of Advanced Pulmonary Vascular Remodeling in Obstructive Hypertrophic Cardiomyopathy With Pulmonary Hypertension. Chest. 2022 Oct 13. PMID: 36243062.
    Citations:    Fields:    
    Citations:    Fields:    
  3. Smirnova NF, Riemondy K, Bueno M, Collins S, Suresh P, Wang X, Patel KN, Cool C, Königshoff M, Sharma NS, Eickelberg O. Single-cell transcriptome mapping identifies a local, innate B cell population driving chronic rejection after lung transplantation. JCI Insight. 2022 09 22; 7(18). PMID: 36134664; PMCID: PMC9675462.
    Citations:    Fields:    Translation:HumansAnimalsCells
  4. Fukumoto J, Lin M, Banday MM, Patil SS, Krishnamurthy S, Breitzig M, Soundararajan R, Galam L, Narala VR, Johns C, Patel K, Dunning J, Lockey RF, Sharma NS, Kolliputi N. Aberrant Expression of ACO1 in Vasculatures Parallels Progression of Idiopathic Pulmonary Fibrosis. Front Pharmacol. 2022; 13:890380. PMID: 35910393.
  5. Roesel MJ, Sharma NS, Schroeter A, Matsunaga T, Xiao Y, Zhou H, Tullius SG. Primary Graft Dysfunction: The Role of Aging in Lung Ischemia-Reperfusion Injury. Front Immunol. 2022; 13:891564. PMID: 35686120; PMCID: PMC9170999.
    Citations:    Fields:    Translation:Humans
  6. Hayes D, Board A, Calfee CS, Ellington S, Pollack LA, Kathuria H, Eakin MN, Weissman DN, Callahan SJ, Esper AM, Crotty Alexander LE, Sharma NS, Meyer NJ, Smith LS, Novosad S, Evans ME, Goodman AB, Click ES, Robinson RT, Ewart G, Twentyman E. Pulmonary and Critical Care Considerations for e-Cigarette, or Vaping, Product Use-Associated Lung Injury. Chest. 2022 07; 162(1):256-264. PMID: 35257738.
    Citations:    Fields:    Translation:Humans
  7. Hayes D, Sharma NS. A growing trend: CFTR modulators for cystic fibrosis lung transplant recipients. J Heart Lung Transplant. 2022 02; 41(2):127-128. PMID: 34924264.
    Citations:    Fields:    Translation:Humans
  8. Margaroli C, Benson P, Sharma NS, Madison MC, Robison SW, Arora N, Ton K, Liang Y, Zhang L, Patel RP, Gaggar A. Spatial mapping of SARS-CoV-2 and H1N1 lung injury identifies differential transcriptional signatures. Cell Rep Med. 2021 04 20; 2(4):100242. PMID: 33778787; PMCID: PMC7985929.
    Citations: 9     Fields:    Translation:HumansCells
  9. Payne GA, Sharma NS, Lal CV, Song C, Guo L, Margaroli C, Viera L, Kumar S, Li J, Xing D, Bosley M, Xu X, Wells JM, George JF, Tallaj J, Leesar M, Blalock JE, Gaggar A. Prolyl endopeptidase contributes to early neutrophilic inflammation in acute myocardial transplant rejection. JCI Insight. 2021 03 22; 6(6). PMID: 33571164; PMCID: PMC8026194.
    Citations:    Fields:    Translation:HumansAnimalsCells
  10. Banday MM, Kumar A, Vestal G, Sethi J, Patel KN, O'Neill EB, Finan J, Cheng F, Lin M, Davis NM, Goldberg H, Coppolino A, Mallidi HR, Dunning J, Visner G, Gaggar A, Seyfang A, Sharma NS. N-myc-interactor mediates microbiome induced epithelial to mesenchymal transition and is associated with chronic lung allograft dysfunction. J Heart Lung Transplant. 2021 06; 40(6):447-457. PMID: 33781665.
    Citations: 1     Fields:    Translation:HumansCells
  11. Sethi J, Bugajski A, Patel KN, Davis NM, Wille KM, Qureshi MR, Banday MM, Lin M, Emani V, Weill D, Tumin D, Hayes D, Sharma NS. Recipient Age Impacts Long-Term Survival in Adult Subjects with Cystic Fibrosis after Lung Transplantation. Ann Am Thorac Soc. 2021 01; 18(1):44-50. PMID: 32795188.
    Citations: 2     Fields:    Translation:Humans
  12. Rinewalt D, Coppolino A, Seethala R, Sharma N, Salim A, Keller S, Mallidi HR. COVID-19 patient bridged to recovery with veno-venous extracorporeal membrane oxygenation. J Card Surg. 2020 Oct; 35(10):2869-2871. PMID: 32668041; PMCID: PMC7405208.
    Citations: 2     Fields:    Translation:HumansCellsPHPublic Health
  13. Sharma NS, Vestal G, Wille K, Patel KN, Cheng F, Tipparaju S, Tousif S, Banday MM, Xu X, Wilson L, Nair VS, Morrow C, Hayes D, Seyfang A, Barnes S, Deshane JS, Gaggar A. Differences in airway microbiome and metabolome of single lung transplant recipients. Respir Res. 2020 May 06; 21(1):104. PMID: 32375889; PMCID: PMC7201609.
    Citations: 8     Fields:    Translation:Humans
  14. Sutariya V, Kelly SJ, Weigel RG, Tur J, Halasz K, Sharma NS, Tipparaju SM. Nanoparticle drug delivery characterization for fluticasone propionate and in vitro testing 1. Can J Physiol Pharmacol. 2019 Jul; 97(7):675-684. PMID: 31100204.
    Citations:    Fields:    Translation:AnimalsCells
  15. Fukumoto J, Leung J, Cox R, Czachor A, Parthasarathy PT, Lagishetty V, Mandry M, Hosseinian N, Patel P, Perry B, Breitzig MT, Alleyn M, Failla A, Cho Y, Cooke AJ, Galam L, Soundararajan R, Sharma N, Lockey RF, Kolliputi N. Oxidative stress induces club cell proliferation and pulmonary fibrosis in Atp8b1 mutant mice. Aging (Albany NY). 2019 01 13; 11(1):209-229. PMID: 30636723; PMCID: PMC6339797.
    Citations: 6     Fields:    Translation:AnimalsCells
  16. Sharma NS, Lal CV, Li JD, Lou XY, Viera L, Abdallah T, King RW, Sethi J, Kanagarajah P, Restrepo-Jaramillo R, Sales-Conniff A, Wei S, Jackson PL, Blalock JE, Gaggar A, Xu X. The neutrophil chemoattractant peptide proline-glycine-proline is associated with acute respiratory distress syndrome. Am J Physiol Lung Cell Mol Physiol. 2018 11 01; 315(5):L653-L661. PMID: 30091378; PMCID: PMC6295514.
    Citations: 7     Fields:    Translation:HumansAnimalsCells
  17. Hough KP, Wilson LS, Trevor JL, Strenkowski JG, Maina N, Kim YI, Spell ML, Wang Y, Chanda D, Dager JR, Sharma NS, Curtiss M, Antony VB, Dransfield MT, Chaplin DD, Steele C, Barnes S, Duncan SR, Prasain JK, Thannickal VJ, Deshane JS. Unique Lipid Signatures of Extracellular Vesicles from the Airways of Asthmatics. Sci Rep. 2018 07 09; 8(1):10340. PMID: 29985427; PMCID: PMC6037776.
    Citations: 48     Fields:    Translation:HumansCellsPHPublic Health
  18. Lal CV, Olave N, Travers C, Rezonzew G, Dolma K, Simpson A, Halloran B, Aghai Z, Das P, Sharma N, Xu X, Genschmer K, Russell D, Szul T, Yi N, Blalock JE, Gaggar A, Bhandari V, Ambalavanan N. Exosomal microRNA predicts and protects against severe bronchopulmonary dysplasia in extremely premature infants. JCI Insight. 2018 03 08; 3(5). PMID: 29515035.
    Citations: 37     Fields:    Translation:HumansAnimalsCells
  19. Garcia B, Sharma N, Johnson K, Salgado J, Wille K. Clinical Outcomes of Paramyxovirus Infections in Lung Transplant Recipients Treated With Oral Ribavirin: A Two-Center Case Series. Exp Clin Transplant. 2019 06; 17(3):393-397. PMID: 29108516.
    Citations: 3     Fields:    Translation:Humans
  20. Sharma NS, Wille KM, Athira S, Zhi D, Hough KP, Diaz-Guzman E, Zhang K, Kumar R, Rangarajan S, Eipers P, Wang Y, Srivastava RK, Rodriguez Dager JV, Athar M, Morrow C, Hoopes CW, Chaplin DD, Thannickal VJ, Deshane JS. Distal airway microbiome is associated with immunoregulatory myeloid cell responses in lung transplant recipients. J Heart Lung Transplant. 2017 Jul 15. PMID: 28756121; PMCID: PMC5893420.
    Citations: 6     Fields:    
  21. Sharma NS, Hartwig MG, Hayes D. Extracorporeal membrane oxygenation in the pre and post lung transplant period. Ann Transl Med. 2017 Feb; 5(4):74. PMID: 28275619; PMCID: PMC5337201.
    Citations: 4     
  22. Chanda D, Kurundkar A, Rangarajan S, Locy M, Bernard K, Sharma NS, Logsdon NJ, Liu H, Crossman DK, Horowitz JC, De Langhe S, Thannickal VJ. Developmental Reprogramming in Mesenchymal Stromal Cells of Human Subjects with Idiopathic Pulmonary Fibrosis. Sci Rep. 2016 11 21; 6:37445. PMID: 27869174; PMCID: PMC5116673.
    Citations: 20     Fields:    Translation:HumansCells
  23. Diaz-Guzman E, Sharma NS, Wille K, Hoopes CW. Use of a novel pulmonary artery cannula to provide extracorporeal membrane oxygenation as a bridge to lung transplantation. J Heart Lung Transplant. 2016 08; 35(8):1051-3. PMID: 27377218.
    Citations: 4     Fields:    Translation:Humans
  24. Kulkarni T, Sharma NS, Diaz-Guzman E. Extracorporeal membrane oxygenation in adults: A practical guide for internists. Cleve Clin J Med. 2016 May; 83(5):373-84. PMID: 27168514.
    Citations: 7     Fields:    Translation:Humans
  25. Sharma NS, Wille KM, Bellot SC, Diaz-Guzman E. Automated Rotational Percussion Bed and Bronchoscopy Improves Respiratory Mechanics and Oxygenation in ARDS Patients Supported with Extracorporeal Membrane Oxygenation. ASAIO J. 2016 May-Jun; 62(3):e27-9. PMID: 26771392.
    Citations: 1     Fields:    Translation:Humans
  26. Sharma NS, Peters T, Kulkarni T, Hoopes CW, Bellot SC, Wille KM, Diaz-Guzman E. Flexible Bronchoscopy Is Safe and Effective in Adult Subjects Supported With Extracorporeal Membrane Oxygenation. Respir Care. 2016 May; 61(5):646-51. PMID: 26814220.
    Citations: 2     Fields:    Translation:Humans
  27. Sharma NS, Wille KM, Zhi D, Thannickal VJ, Brodie DM, Hoopes CW, Diaz-Guzman E. Use of ECMO in the Management of Severe Acute Respiratory Distress Syndrome: A Survey of Academic Medical Centers in the United States. ASAIO J. 2015 Sep-Oct; 61(5):556-63. PMID: 25914957.
    Citations: 2     Fields:    Translation:Humans
  28. Teerapuncharoen K, Sharma NS, Barker AB, Wille KM, Diaz-Guzman E. Successful Treatment of Severe Carbon Monoxide Poisoning and Refractory Shock Using Extracorporeal Membrane Oxygenation. Respir Care. 2015 Sep; 60(9):e155-60. PMID: 25922545.
    Citations: 3     Fields:    Translation:Humans
  29. Sharma NS, Wille KM, Diaz Guzman E. Extracorporeal membrane oxygenation after liver transplantation in a patient with hepatopulmonary syndrome and an atrial septal defect. Int J Artif Organs. 2015 Mar; 38(3):170-2. PMID: 25837880.
    Citations: 3     Fields:    Translation:Humans
  30. Sharma NS, Wille KM, Bellot SC, Diaz-Guzman E. Modern use of extracorporeal life support in pregnancy and postpartum. ASAIO J. 2015 Jan-Feb; 61(1):110-4. PMID: 25248040.
    Citations: 27     Fields:    Translation:Humans
  31. Wille KM, Sharma NS, Kulkarni T, Lammi MR, Barney JB, Bellot SC, Cantor RS, Naftel DC, Diaz-Guzman E, McGiffin DC. Characteristics of patients with pulmonary venoocclusive disease awaiting transplantation. Ann Am Thorac Soc. 2014 Nov; 11(9):1411-8. PMID: 25296345.
    Citations: 4     Fields:    Translation:Humans
  32. Sharma N, Venado A, Morrison J. Protocol-based treatment of septic shock, fibrinolysis for submassive pulmonary embolism, and use of corticosteroids in acute exacerbations of chronic obstructive pulmonary disease requiring mechanical ventilation. Am J Respir Crit Care Med. 2014 10 01; 190(7):827-8. PMID: 25271746.
    Citations: 2     Fields:    Translation:Humans
  33. Sharma NS, Wille KM, Hoopes CW, Diaz-Guzman E. Acute demyelinating polyneuropathy after lung transplantation: guillain-barré syndrome or tacrolimus toxicity? Case Rep Transplant. 2014; 2014:685010. PMID: 25184071.
    Citations: 1     
  34. Chopra A, Shim C, Sharma N, Gordon D, Tibb A. Primary salivary type lung tumor: Mucoepidermoid carcinoma. Respir Med Case Rep. 2013; 9:18-20. PMID: 26029623; PMCID: PMC3949550.
    Citations: 9     
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.