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Kunpeng Pang, Ph.D.

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Overview
Dr. Pang is an Ophthalmologist, and devotes to the study of bioengineered cornea substitute with stem cells and biomaterials as well as the molecular and cellular regulation of corneal stroma scar formation. During his postgraduate studies (2006- 2011), he focused on the study of the development of the tissue engineering cornea, and first constructed the rabbit anterior corneal lamella substitute using acellular porcine cornea matrix with in vitro expanded cornea epithelial and stromal cells under the guidance of Dr. Wu (Biomaterials 2010). Next, he has been working in Qilu Hospital of Shandong University to be an Ophthalmologist and cooperated with his group to successfully obtain the human embryonic stem cells (hESCs) derived corneal epithelial like (CEpi) and endothelial (CEndo) like cells that for three-dimensional construction of full-thickness cornea substitute(Stem Cells Dev 2014; Biomaterials 2017; PLoS One 2017; Stem cells 2020).Recently, they have remodified the acellular porcine corneal matrix with enhance biological activity for deep lamellar transplantation of rabbit cornea (J Biomater Appl 2020). Next, they will continue to do further research in cornea regenerative medicine and apply for grants to support this study.
In clinic, Dr Pang treats a variety of patients with ocular surface, cataract, and refractive conditions at Qilu Hospital of Shandong University. His clinical expertise includes the treatment of patients with complex corneal diseases (infections, immune problems, trauma, scarring), dry eye, and refractive conditions. He performs surgeries of partial or full thickness corneal transplantation, and first perform the surgery of the small incision lenticule extraction (SMILE) for myopia treatment in Qilu hospital. Moreover, he is also specialized in cataract surgeries, LASIK and LASEK. In addition, he is doing the clinical research for the treatment and prevention of corneal neovascularization as well as the strategy for the treatment of fungal keratitis.

Bibliographic
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Wang Q, Zhou H, Sun Y, Cao C, Pang K. Modified acellular porcine corneal matrix in deep lamellar transplantation of rabbit cornea. J Biomater Appl. 2020 03; 34(8):1092-1104. PMID: 31896290.
    Citations:    Fields:    
  2. Zhu J, Wang LY, Li CY, Wu JY, Zhang YT, Pang KP, Wei Y, Du LQ, Liu M, Wu XY. SPARC promotes self-renewal of limbal epithelial stem cells and ocular surface restoration through JNK and p38-MAPK signaling pathways. Stem Cells. 2020 01; 38(1):134-145. PMID: 31644832.
    Citations: 2     Fields:    Translation:HumansAnimalsCells
  3. Wang J, He Y, Pang K, Zeng Q, Zhang X, Ren F, Guo H. Changes in milk yield and composition of colostrum and regular milk from four buffalo breeds in China during lactation. J Sci Food Agric. 2019 Oct; 99(13):5799-5807. PMID: 31177544.
    Citations: 1     Fields:    Translation:Animals
  4. Zhang C, Du L, Pang K, Wu X. Differentiation of human embryonic stem cells into corneal epithelial progenitor cells under defined conditions. PLoS One. 2017; 12(8):e0183303. PMID: 28813511.
    Citations: 6     Fields:    Translation:HumansCells
  5. Zhang C, Du L, Sun P, Shen L, Zhu J, Pang K, Wu X. Construction of tissue-engineered full-thickness cornea substitute using limbal epithelial cell-like and corneal endothelial cell-like cells derived from human embryonic stem cells. Biomaterials. 2017 04; 124:180-194. PMID: 28199886.
    Citations: 10     Fields:    Translation:HumansAnimalsCells
  6. Pang K, Du L, Zhang K, Dai C, Ju C, Zhu J, Wu X. Three-Dimensional Construction of a Rabbit Anterior Corneal Replacement for Lamellar Keratoplasty. PLoS One. 2016; 11(12):e0168084. PMID: 27930708.
    Citations: 1     Fields:    Translation:Animals
  7. Pang KP, Pan H, Wu XY. [Regulatory analysis of hypoxia on innate immunity of human corneal epithelium]. Zhonghua Yi Xue Za Zhi. 2016 Nov 15; 96(42):3408-3411. PMID: 27866535.
    Citations:    Fields:    Translation:HumansCells
  8. Pang KP, Pan H. [Study on the susceptibility of human corneal epithelial cells to Acanthamoeba in a hypoxia condition]. Zhonghua Yi Xue Za Zhi. 2016 Nov 01; 96(40):3242-3245. PMID: 27852393.
    Citations:    Fields:    Translation:AnimalsCells
  9. Guo H, Pang K, Wei Y, Yi C, Wu X. Herpes virus entry mediator in human corneal epithelial cells modulates the production of inflammatory cytokines in response to HSV type 1 challenge. Ophthalmic Res. 2015; 54(3):128-34. PMID: 26328884.
    Citations: 6     Fields:    Translation:HumansAnimalsCells
  10. Zhang K, Pang K, Wu X. Isolation and transplantation of corneal endothelial cell-like cells derived from in-vitro-differentiated human embryonic stem cells. Stem Cells Dev. 2014 Jun 15; 23(12):1340-54. PMID: 24499373.
    Citations: 28     Fields:    Translation:HumansAnimalsCells
  11. Ju C, Gao L, Wu X, Pang K. A human corneal endothelium equivalent constructed with acellular porcine corneal matrix. Indian J Med Res. 2012 Jun; 135(6):887-94. PMID: 22825608.
    Citations: 8     Fields:    Translation:HumansAnimalsCells
  12. Du L, Wu X, Pang K, Yang Y. Histological evaluation and biomechanical characterisation of an acellular porcine cornea scaffold. Br J Ophthalmol. 2011 Mar; 95(3):410-4. PMID: 20956275.
    Citations: 26     Fields:    Translation:AnimalsCells
  13. Pang K, Du L, Wu X. A rabbit anterior cornea replacement derived from acellular porcine cornea matrix, epithelial cells and keratocytes. Biomaterials. 2010 Oct; 31(28):7257-65. PMID: 20598368.
    Citations: 36     Fields:    Translation:AnimalsCells
  14. Pang K, Wu X. [Identification, purification and culture of limbal epithelial stem cells]. Sheng Wu Yi Xue Gong Cheng Xue Za Zhi. 2009 Apr; 26(2):452-6. PMID: 19499824.
    Citations:    Fields:    Translation:HumansCells
  15. Du LQ, Wu XY, Li MC, Wang SG, Pang KP. Effect of different biomedical membranes on alkali-burned cornea. Ophthalmic Res. 2008 Oct; 40(6):282-90. PMID: 18463426.
    Citations: 2     Fields:    Translation:Animals
  16. Zheng LM, Zhang LD, Guo HY, Pang K, Zhang WJ, Ren FZ. [Optimizing spectral region in using near-infrared spectroscopy for donkey milk analysis]. Guang Pu Xue Yu Guang Pu Fen Xi. 2007 Nov; 27(11):2224-7. PMID: 18260400.
    Citations:    Fields:    Translation:Animals
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.